Lars Hviid
Professor
Centre for Medical Parasitology
CMP
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-11-TR4
Member of:
SURFACE team
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Unraveling the impact of malaria exposure before birth
Hviid, Lars, 2009, In: PLoS Medicine. 6, 7, p. e1000117Research output: Contribution to journal › Journal article › Research › peer-review
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No sweet deal: the antibody-mediated immune response to malaria
Hviid, Lars, Lopez-Perez, Mary, Larsen, M. D. & Vidarsson, G., 2022, In: Trends in Parasitology. 38, 6, p. 428-434Research output: Contribution to journal › Review › Research › peer-review
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Biochemical characterization, localization and immunostimulating properties of a soluble glycoprotein, Ag1, isolated from in vitro cultures of Plasmodium falciparum
Jakobsen, P. H., Jepsen, S., Riley, E. M., Theander, Thor Grundtvig, Grellier, P., Lihme, A., Hviid, Lars, Dziegiel, Morten Hanefeld & Schrevel, J., 1990, In: Parasitology Reseach. 76, 8, p. 657-61 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased plasma levels of soluble IL-2R are associated with severe Plasmodium falciparum malaria
Jakobsen, P. H., Morris-Jones, S., Theander, Thor Grundtvig, Hviid, Lars, Hansen, M. B., Bendtzen, K., Ridley, R. G. & Greenwood, B. M., 1994, In: Clinical and Experimental Immunology. 96, 1, p. 98-103 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Soluble haemoglobin is a marker of recent Plasmodium falciparum infections
Jakobsen, P. H., Bygbjerg, Ib Christian, Theander, Thor Grundtvig, Hviid, Lars, Fujioka, H., Aikawa, M., Bayoumi, R. A. & Koch, C., 1997, In: Immunology Letters. 59, 1, p. 35-42 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibody reactivities to glutamate-rich peptides of Plasmodium falciparum parasites in humans from areas of different malaria endemicity
Jakobsen, P. H., Theander, Thor Grundtvig, Hviid, Lars, Morris-Jones, S., Jensen, J. B., Bayoumi, R. A., Greenwood, B. M., Bygbjerg, Ib Christian & Heegaard, P. M., 1996, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 104, 10, p. 734-40 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibody responses to Rhoptry-Associated Protein-1 (RAP-1) of Plasmodium falciparum parasites in humans from areas of different malaria endemicity
Jakobsen, P. H., Kurtzhals, Jørgen, Riley, E. M., Hviid, Lars, Theander, Thor Grundtvig, Morris-Jones, S., Jensen, J. B., Bayoumi, R. A., Ridley, R. G. & Greenwood, B. M., 1997, In: Parasite Immunology. 19, 9, p. 387-93 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Specific T-cell recognition of the merozoite proteins rhoptry-associated protein 1 and erythrocyte-binding antigen 1 of Plasmodium falciparum
Jakobsen, P. H., Hviid, Lars, Theander, Thor Grundtvig, Afare, E. A., Ridley, R. G., Heegaard, P. M., Stuber, D., Dalsgaard, K. & Nkrumah, F. K., 1993, In: Infection and Immunity. 61, 1, p. 268-73 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Isolation and characterization of a soluble antigen complex of Plasmodium falciparum with pyrogenic properties
Jakobsen, P. H., Hviid, Lars, Theander, Thor Grundtvig, Riley, E. M., Grellier, P., Bruun, L. S., Dalsgaard, K., Schrevel, J. & Jepsen, S., 1991, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 99, 1, p. 21-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased plasma concentrations of sICAM-1, sVCAM-1 and sELAM-1 in patients with Plasmodium falciparum or P. vivax malaria and association with disease severity
Jakobsen, P. H., Morris-Jones, S., Rønn, A., Hviid, Lars, Theander, Thor Grundtvig, Elhassan, I. M., Bygbjerg, Ib Christian & Greenwood, B. M., 1994, In: Immunology. 83, 4, p. 665-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Anti-phospholipid antibodies in patients with Plasmodium falciparum malaria
Jakobsen, P. H., Morris-Jones, S. D., Hviid, Lars, Theander, Thor Grundtvig, Høier-Madsen, M., Bayoumi, R. A. & Greenwood, B. M., 1993, In: Immunology. 79, 4, p. 653-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Malaria immunology: Targeting the surface of infected erythrocytes
Jensen, Anja Ramstedt (ed.) & Hviid, Lars (ed.), 2022, Humana Press. 796 p. (Methods in Molecular Biology, Vol. 2470).Research output: Book/Report › Book › Research › peer-review
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Cerebral Plasmodium falciparum malaria: The role of PfEMP1 in its pathogenesis and immunity, and PfEMP1-based vaccines to prevent it
Jensen, Anja Ramstedt, Adams, Yvonne & Hviid, Lars, 2020, In: Immunological Reviews. 293, 1, p. 230-252Research output: Contribution to journal › Review › Research › peer-review
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Lack of gender-specific antibody recognition of products from domains of a var gene implicated in pregnancy-associated Plasmodium falciparum malaria
Jensen, Anja Ramstedt, Zornig, H. D., Buhmann, Cæcilie Christine Böck, Salanti, Ali, Koram, K. A., Riley, E. M., Theander, Thor Grundtvig, Hviid, Lars & Staalsoe, T., 2003, In: Infection and Immunity. 71, 7, p. 4193-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes
Jensen, Anja Ramstedt, Magistrado, P., Sharp, S., Joergensen, L., Lavstsen, Thomas, Chiucchiuini, A., Salanti, Ali, Vestergaard, L. S., Lusingu, J. P., Hermsen, R., Sauerwein, R., Christensen, J., Nielsen, Morten Agertoug, Hviid, Lars, Sutherland, C., Staalsoe, T. & Theander, Thor Grundtvig, 2004, In: Journal of Experimental Medicine. 199, 9, p. 1179-90 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multiple Plasmodium falciparum erythrocyte membrane protein 1 variants per genome can bind IgM via its Fc fragment Fcμ
Jeppesen, A., Ditlev, S. B., Soroka, V., Stevenson, E. K., Turner, Louise, Dzikowski, R., Hviid, Lars & Barfod, Lea Klingenberg, 2015, In: Infection and Immunity. 83, 10, p. 3972-81 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dansk malariaforskning fra spæd begyndelse til international styrkeposition
Jepsen, M. P. G., Jepsen, S., Kurtzhals, Jørgen & Hviid, Lars, 2017, In: Ugeskrift for Laeger. 179, 20, p. 866-869 V10160756.Research output: Contribution to journal › Journal article › Research › peer-review
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CCR3 expression induced by IL-2 and IL-4 functioning as a death receptor for B cells
Jinquan, T., Jacobi, H. H., Jing, C., Millner, A., Sten, E., Hviid, Lars, Anting, L., Ryder, L. P., Glue, C., Skov, P. S., Jarman, E., Lamberth, K., Malling, H. & Poulsen, Lars K., 2003, In: Journal of Immunology. 171, 4, p. 1722-31 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The kinetics of antibody binding to Plasmodium falciparum VAR2CSA PfEMP1 antigen and modelling of PfEMP1 antigen packing on the membrane knobs
Joergensen, L. M., Salanti, Ali, Dobrilovic, T., Barfod, Lea Klingenberg, Hassenkam, Tue, Theander, Thor Grundtvig, Hviid, Lars & Arnot, D. E., 2010, In: Malaria Journal. 9, 1, p. 100Research output: Contribution to journal › Journal article › Research › peer-review
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Frequency of electrocardiographic alterations and pericardial effusion in patients with uncomplicated malaria
Kaagaard, M. D., Matos, L. O., Holm, A. E., Gomes, L. C., Wegener, A., Lima, K. O., Vieira, I. V. M., de Souza, R. M., Marinho, C. R. F., Hviid, Lars, Vestergaard, L. S., Dominguez, Helena, Biering-Sørensen, Tor, Silvestre, O. M. & Brainin, P., 2022, In: American Journal of Cardiology. 165, p. 116-123Research output: Contribution to journal › Journal article › Research › peer-review
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Aligned hemozoin crystals in curved clusters in malarial red blood cells revealed by nanoprobe X-ray Fe fluorescence and diffraction
Kapishnikov, S., Berthing, T., Hviid, Lars, Dierolf, M., Menzel, A., Pfeiffer, F., Als-Nielsen, Jens & Leiserowitz, L., 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 28, p. 11184-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interferon-¿- and tumour necrosis factor-a-producing cells in humans who are immune to cutaneous leishmaniasis
Kemp, K., Theander, Thor Grundtvig, Hviid, Lars, Garfar, A., Kharazmi, A. & Kemp, M., 1999, In: Scandinavian Journal of Immunology. 49, 6, p. 655-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Leishmania-specific T cells expressing interferon-¿(IFN-¿) and IL-10 upon activation are expanded in individuals cured of visceral leishmaniasis
Kemp, K., Kemp, M., Kharazmi, A., Ismail, A., Kurtzhals, Jørgen, Hviid, Lars & Theander, Thor Grundtvig, 1999, In: Clinical and Experimental Immunology. 116, 3, p. 500-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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West African donors have high percentages of activated cytokine producing T cells that are prone to apoptosis
Kemp, K., Akanmori, B. D. & Hviid, Lars, 2001, In: Clinical and Experimental Immunology. 126, 1, p. 69-75 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cytokine production and apoptosis among T cells from patients under treatment for Plasmodium falciparum malaria
Kemp, K., Akanmori, B. D., Adabayeri, V., Goka, B. Q., Kurtzhals, Jørgen, Behr, C. & Hviid, Lars, 2002, In: Clinical and Experimental Immunology. 127, 1, p. 151-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interferon-¿ production by human T cells and natural killer cells in vitro in response to antigens from the two intracellular pathogens Mycobacterium tuberculosis and Leishmania major
Kemp, K., Hviid, Lars, Kharazmi, A. & Kemp, M., 1997, In: Scandinavian Journal of Immunology. 46, 5, p. 495-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased levels of soluble CD30 in plasma of patients with Plasmodium falciparum malaria
Kemp, K., Kurtzhals, Jørgen, Akanmori, B. D., Adabayeri, V., Goka, B. Q., Behr, C. & Hviid, Lars, 2002, In: Clinical and Vaccine Immunology. 9, 3, p. 720-2 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Acute P. falciparum malaria induces a loss of CD28- T IFN-¿ producing cells
Kemp, K., Akanmori, B. D., Kurtzhals, J. A. L., Adabayeri, V., Goka, B. Q. & Hviid, Lars, 2002, In: Parasite Immunology. 24, 11-12, p. 545-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Activation of human T lymphocytes by Leishmania lipophosphoglycan
Kemp, M., Theander, Thor Grundtvig, Handman, E., Hey, A. S., Kurtzhals, Jørgen, Hviid, Lars, Sørensen, A. L., Were, J. O., Koech, D. K. & Kharazmi, A., 1991, In: Scandinavian Journal of Immunology. 33, 2, p. 219-24 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of IgG with specificity for variant surface antigens expressed by placental Plasmodium falciparum isolates
Khattab, A., Reinhardt, C., Staalsoe, T., Fievet, N., Kremsner, P. G., Deloron, P., Hviid, Lars & Klinkert, M., 2004, In: Malaria Journal. 3, p. 21Research output: Contribution to journal › Journal article › Research › peer-review
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Reversible suppression of bone marrow response to erythropoietin in Plasmodium falciparum malaria
Kurtzhals, Jørgen, Rodrigues, O., Addae, M., Commey, J. O., Nkrumah, F. K. & Hviid, Lars, 1997, In: British Journal of Haematology. 97, 1, p. 169-74 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The importance of strict patient definition in studies of malaria pathogenesis
Kurtzhals, Jørgen, Goka, B. Q., Akanmori, B. D. & Hviid, Lars, 2001, In: Trends in Parasitology. 17, 7, p. 313-4 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased eosinophil activity in acute Plasmodium falciparum infection - association with cerebral malaria
Kurtzhals, Jørgen, Reimert, C. M., Tette, E., Dunyo, S. K., Koram, K. A., Akanmori, B. D., Nkrumah, F. K. & Hviid, Lars, 1998, In: Clinical and Experimental Immunology. 112, 2, p. 303-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Low plasma concentrations of interleukin 10 in severe malarial anaemia compared with cerebral and uncomplicated malaria
Kurtzhals, Jørgen, Adabayeri, V., Goka, B. Q., Akanmori, B. D., Oliver-Commey, J. O., Nkrumah, F. K., Behr, C. & Hviid, Lars, 1998, In: Lancet. 351, 9118, p. 1768-72 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Anaemia caused by asymptomatic Plasmodium falciparum infection in semi-immune African schoolchildren
Kurtzhals, Jørgen, Addae, M. M., Akanmori, B. D., Dunyo, S., Koram, K. A., Appawu, M. A., Nkrumah, F. K. & Hviid, Lars, 1999, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 93, 6, p. 623-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The cytokine balance in severe malarial anemia
Kurtzhals, Jørgen, Akanmori, B. D., Goka, B. Q., Adabayeri, V., Nkrumah, F. K., Behr, C. & Hviid, Lars, 1999, In: Journal of Infectious Diseases. 180, 5, p. 1753-5 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Suitability of IgG responses to multiple Plasmodium falciparum antigens as markers of transmission intensity and pattern
Kyei-Baafour, E., Oppong, M., Kusi, K. A., Frempong, A. F., Aculley, B., Arthur, F. K. N., Tiendrebeogo, R. W., Singh, S. K., Theisen, Michael, Kweku, M., Adu, B., Hviid, Lars & Ofori, M. F., 2021, In: PLoS ONE. 16, 4, e0249936.Research output: Contribution to journal › Journal article › Research › peer-review
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Enzyme-linked immunosorbent assay for activation of the classical complement pathway by Plasmodium falciparum-infected erythrocyte surface antigen-specific antibodies
Larsen, M. D., Bayarri-Olmos, R., Garred, Peter & Hviid, Lars, 2022, In: Methods in Molecular Biology. 2470, p. 673-678 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination
Larsen, M. D., Lopez-Perez, Mary, Dickson, E. K., Ampomah, P., Tuikue Ndam, N., Nouta, J., Koeleman, C. A. M., Ederveen, A. L. H., Mordmüller, B., Salanti, Ali, Nielsen, Morten Agertoug, Massougbodji, A., van der Schoot, C. E., Ofori, M. F., Wuhrer, M., Hviid, Lars & Vidarsson, G., 2021, In: Nature Communications. 12, 5838.Research output: Contribution to journal › Journal article › Research › peer-review
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Malaria parasite evasion of classical complement pathway attack
Larsen, M. D., Ditlev, S., Olmos, R. B., Ampomah, P., Ofori, M. F., Garred, Peter & Hviid, Lars, 2017, In: Molecular Immunology. 89, p. 159-159Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Evasion of classical complement pathway activation on Plasmodium falciparum-infected erythrocytes opsonized by PfEMP1-specific IgG
Larsen, M. D., Quintana Varon, Maria del Pilar, Ditlev, S. B., Bayarri-Olmos, R., Ofori, M. F., Hviid, Lars & Garred, Peter, 2019, In: Frontiers in Immunology. 9, 3088.Research output: Contribution to journal › Journal article › Research › peer-review
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Expression of Plasmodium falciparum erythrocyte membrane protein 1 in experimentally infected humans
Lavstsen, Thomas, Magistrado, P., Hermsen, C. C., Salanti, Ali, Jensen, Anja Ramstedt, Sauerwein, R., Hviid, Lars, Theander, Thor Grundtvig & Staalsoe, T., 2005, In: Malaria Journal. 4, 1, p. 21Research output: Contribution to journal › Journal article › Research › peer-review
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Structure-guided identification of a family of dual receptor-binding PfEMP1 that is associated with cerebral malaria
Lennartz, F., Adams, Y., Bengtsson, A., Olsen, R. W., Turner, L., Ndam, N. T., Ecklu-Mensah, G. D., Moussiliou, A., Ofori, M. F., Gamain, B., Lusingu, J. P., Petersen, J. E. V., Wang, C. W., Nunes-Silva, S., Jespersen, J. S., Lau, C. K. Y., Theander, T. G., Lavstsen, T., Hviid, L., Higgins, M. K. & 1 others, , 8 Mar 2017, In: Cell Host & Microbe. 21, 3, p. 403-414 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Vß profiles in African children with acute cerebral or uncomplicated malaria: very focused changes among a remarkable global stability
Loizon, S., Boeuf, P., Tetteh, J. K. A., Goka, B., Obeng-Adjei, G., Kurtzhals, J. A. L., Rogier, C., Akanmori, B. D., Mercereau-Puijalon, O., Hviid, Lars & Behr, C., 2007, In: Microbes and Infection. 9, 11, p. 1252-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biomarker of Anopheles exposure in Ghanaian children with hemoglobin S and C
Londono-Renteria, B., Seidu, Zakaria, Lamptey, H., Ofori, M. F., Hviid, Lars & Lopez-Perez, Mary, 2024, In: Acta Tropica. 249, 8 p., 107043.Research output: Contribution to journal › Journal article › Research › peer-review
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PfEMP1-specific immunoglobulin G reactivity among Beninese pregnant women with sickle cell trait
Lopez-Perez, Mary, Viwami, F., Seidu, Zakaria, Jensen, Anja Ramstedt, Doritchamou, J., Ndam, N. T. & Hviid, Lars, 2021, In: Open Forum Infectious Diseases. 8, 12, ofab527.Research output: Contribution to journal › Journal article › Research › peer-review
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Binding of human serum proteins to Plasmodium falciparum-infected erythrocytes and its association with malaria clinical presentation
Lopez-Perez, Mary, van der Puije, W., Castberg, F. C., Ofori, M. F. & Hviid, Lars, 2020, In: Malaria Journal. 19, 1, 362.Research output: Contribution to journal › Journal article › Research › peer-review
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IgG responses to the Plasmodium falciparum antigen VAR2CSA in Colombia are restricted to pregnancy and are not induced by exposure to Plasmodium vivax
Lopez-Perez, Mary, Larsen, M. D., Bayarri-Olmos, R., Ampomah, P., Stevenson, L., Arévalo-Herrera, M., Herrera, S. & Hviid, Lars, 2018, In: Infection and Immunity. 86, 8, e00136-18.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural acquired immunity to malaria antigens among pregnant women with hemoglobin C trait
Lopez-Perez, Mary, Viwami, F., Doritchamou, J., Ndam, N. T. & Hviid, Lars, 2022, In: American Journal of Tropical Medicine and Hygiene. 106, 3, p. 853–856Research output: Contribution to journal › Journal article › Research › peer-review
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Levels of plasma immunoglobulin G with specificity against the cysteine-rich interdomain regions of a semiconserved Plasmodium falciparum erythrocyte membrane protein 1, VAR4, predict protection against malarial anemia and febrile episodes
Lusingu, J. P. A., Jensen, Anja Ramstedt, Vestergaard, L. S., Minja, D. T., Dalgaard, M. B., Gesase, S., Mmbando, B. P., Kitua, A. Y., Lemnge, M. M., Cavanagh, D., Hviid, Lars & Theander, Thor Grundtvig, 2006, In: Infection and Immunity. 74, 5, p. 2867-75 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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VAR2CSA expression on the surface of placenta-derived Plasmodium falciparum-infected erythrocytes
Magistrado, P., Salanti, Ali, Tuikue Ndam, N. G., Mwakalinga, S. B., Resende, M., Dahlbäck, M., Hviid, Lars, Lusingu, J., Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2008, In: Journal of Infectious Diseases.Research output: Contribution to journal › Journal article › Research › peer-review
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CD36 selection of 3D7 Plasmodium falciparum associated with severe childhood malaria results in reduced VAR4 expression
Magistrado, P., Staalsoe, T., Theander, Thor Grundtvig, Hviid, Lars & Jensen, Anja Ramstedt, 2008, In: Malaria Journal. 7, 1, p. 204Research output: Contribution to journal › Journal article › Research › peer-review
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Immunoglobulin G antibody reactivity to a group A Plasmodium falciparum erythrocyte membrane protein 1 and protection from P. falciparum malaria
Magistrado, P. A., Lusingu, J., Vestergaard, L. S., Lemnge, M., Lavstsen, Thomas, Turner, Louise, Hviid, Lars, Jensen, Anja Ramstedt & Theander, Thor Grundtvig, 2007, In: Infection and Immunity. 75, 5, p. 2415-20 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Variant-specific immunity to Plasmodium berghei in pregnant mice
Megnekou, R., Hviid, Lars & Staalsoe, T., 2009, In: Infection and Immunity. 77, 5, p. 1827-34 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cytokine response to pregnancy-associated recrudescence of Plasmodium berghei infection in mice with pre-existing immunity to malaria
Megnekou, R., Staalsø, Trine & Hviid, Lars, 1 Nov 2013, In: Malaria Journal. 12, 1, p. 387Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of pregnancy and intensity of Plasmodium falciparum transmission on immunoglobulin G subclass responses to variant surface antigens
Megnekou, R., Staalsoe, T., Taylor, D. W., Leke, R. & Hviid, Lars, 2005, In: Infection and Immunity. 73, 7, p. 4112-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Geographical and temporal conservation of antibody recognition of Plasmodium falciparum variant surface antigens
Nielsen, Morten Agertoug, Vestergaard, L. S., Lusingu, J., Kurtzhals, Jørgen, Giha, H. A., Grevstad, B., Goka, B. Q., Lemnge, M. M., Jensen, J. B., Akanmori, B. D., Theander, Thor Grundtvig, Staalsoe, T. & Hviid, Lars, 2004, In: Infection and Immunity. 72, 6, p. 3531-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential induction of immunoglobulin G to Plasmodium falciparum variant surface antigens during the transmission season in Daraweesh, Sudan
Nielsen, Morten Agertoug, Grevstad, B., A-Elgadir, T. M. E., Kurtzhals, Jørgen, Giha, H., Staalsoe, T., Hviid, Lars & Theander, Thor Grundtvig, 2005, In: Journal of Infectious Diseases. 192, 3, p. 520-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum: VAR2CSA expressed during pregnancy-associated malaria is partially resistant to proteolytic cleavage by trypsin
Nielsen, Morten Agertoug, Resende, M., Alifrangis, Michael, Turner, Louise, Hviid, Lars, Theander, Thor Grundtvig & Salanti, Ali, 2007, In: Experimental Parasitology. 117, 1, p. 1-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum variant surface antigen expression varies between isolates causing severe and nonsevere malaria and is modified by acquired immunity
Nielsen, Morten Agertoug, Staalsoe, T., Kurtzhals, Jørgen, Goka, B. Q., Dodoo, D., Alifrangis, Michael, Theander, Thor Grundtvig, Akanmori, B. D. & Hviid, Lars, 2002, In: Journal of Immunology. 168, 7, p. 3444-50 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pregnancy-associated malaria in a rural community of Ghana
Ofori, M., Ansah, E., Agyepong, I., Ofori-Adjei, D., Hviid, Lars & Akanmori, B., 2009, In: Ghana Medical Journal. 43, 1, p. 13-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Etiology of placental Plasmodium falciparum malaria in African women
Ofori, M. F., Lamptey, H., Dickson, E. K., Kyei-Baafour, E. & Hviid, Lars, 2018, In: The Journal of Infectious Diseases. 218, 2, p. 277-281 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Expression of variant surface antigens by Plasmodium falciparum parasites in the peripheral blood of clinically immune pregnant women indicates ongoing placental infection
Ofori, M. F., Staalsoe, T., Bam, V., Lundquist, M., David, K. P., Browne, E. N. L., Akanmori, B. D. & Hviid, Lars, 2003, In: Infection and Immunity. 71, 3, p. 1584-6 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Malaria-induced acquisition of antibodies to Plasmodium falciparum variant surface antigens
Ofori, M. F., Dodoo, D., Staalsoe, T., Kurtzhals, Jørgen, Koram, K., Theander, Thor Grundtvig, Akanmori, B. D. & Hviid, Lars, 2002, In: Infection and Immunity. 70, 6, p. 2982-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Profiling the Plasmodium falciparum erythrocyte membrane protein 1-specific immununoglobulin G response among Ghanaian children with hemoglobin S and C
Oleinikov, A. V., Seidu, Zakaria, Oleinikov, I. V., Tetteh, M., Lamptey, H., Ofori, M. F., Hviid, Lars & Lopez-Perez, Mary, 2024, In: The Journal of Infectious Diseases. 229, 1, p. 203-213Research output: Contribution to journal › Journal article › Research › peer-review
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Natural and vaccine-induced acquisition of cross-reactive IgG inhibiting ICAM-1-specific binding of a Plasmodium falciparum PfEMP1 subtype associated specifically with cerebral malaria
Olsen, Rebecca Wendelboe, Ecklu-Mensah, G., Bengtsson, A., Ofori, M. F., Lusingu, J. P. A., Castberg, F. C., Hviid, Lars, Adams, Yvonne & Jensen, Anja Ramstedt, 2018, In: Infection and Immunity. 86, 4, 17 p., e00622-17.Research output: Contribution to journal › Journal article › Research › peer-review
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Acquisition of IgG to ICAM-1-Binding DBLβ Domains in the Plasmodium falciparum erythrocyte membrane protein 1 antigen family varies between Groups A, B, and C
Olsen, Rebecca Wendelboe, Ecklu-Mensah, G., Bengtsson, A., Ofori, M. F., Kusi, K. A., Koram, K. A., Hviid, Lars, Adams, Yvonne & Jensen, Anja Ramstedt, 2019, In: Infection and Immunity. 87, 10, e00224-19.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinetics of antibody responses to PfRH5-complex antigens in Ghanaian children with Plasmodium falciparum malaria
Partey, Frederica Dedo, Castberg, F. C., Sarbah, E. W., Silk, S. E., Awandare, G. A., Draper, S. J., Opoku, N., Kweku, M., Ofori, M. F., Hviid, Lars & Barfod, Lea Klingenberg, 2018, In: PLOS ONE. 13, 6, 14 p., e0198371.Research output: Contribution to journal › Journal article › Research › peer-review
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Immunoglobulin M: restrainer of inflammation and mediator of immune evasion by Plasmodium falciparum malaria
Pleass, R. J., Moore, S. C., Stevenson, L. & Hviid, Lars, Feb 2016, In: Trends in Parasitology. 32, 2, p. 108-119 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The density of knobs on Plasmodium falciparum-infected erythrocytes depends on developmental age and varies among isolates
Quadt, K. A., Barfod, Lea Klingenberg, Andersen, D., Bruun, J., Gyan, B., Hassenkam, Tue, Ofori, M. F. & Hviid, Lars, 2012, In: P L o S One. 7, 9, p. e45658Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Haptoglobin 1-1 is associated with susceptibility to severe Plasmodium falciparum malaria
Quaye, I. K., Ekuban, F. A., Goka, B. Q., Adabayeri, V., Kurtzhals, Jørgen, Gyan, B., Ankrah, N. A., Hviid, Lars & Akanmori, B. D., 2000, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 94, 2, p. 216-9 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Measuring naturally acquired phagocytosis-inducing antibodies to Plasmodium falciparum parasites by a flow cytometry-based assay
Quintana Varon, Maria del Pilar, Anabire, N. G. & Hviid, Lars, 6 Aug 2020, In: Journal of visualized experiments : JoVE. 162, e61538.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comprehensive analysis of Fc-mediated IgM binding to the Plasmodium falciparum erythrocyte membrane protein 1 family in three parasite clones
Quintana Varon, Maria del Pilar, Ecklu-Mensah, G., Tcherniuk, S. O., Ditlev, S. B., Oleinikov, A. V., Hviid, Lars & Lopez-Perez, Mary, 2019, In: Scientific Reports. 9, 1, 11 p., 6050.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endemic Burkitt lymphoma - an aggressive childhood cancer linked to Plasmodium falciparum exposure, but not to exposure to other malaria parasites
Quintana Varon, Maria del Pilar, Smith-Togobo, C., Moormann, A. & Hviid, Lars, 2020, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 128, 2, p. 129-135Research output: Contribution to journal › Review › Research › peer-review
- Published
Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA
Raghavan, Sai Sundar Rajan, Dagil, Robert, Lopez-Perez, Mary, Conrad, J., Bassi, Maria Rosaria, Quintana Varon, Maria del Pilar, Choudhary, Swati, Gustavsson, Tobias, Wang, Y., Gourdon, Pontus Emanuel, Ofori, M. F., Christensen, S. B., Minja, D. T. R., Schmiegelow, Christentze, Nielsen, Morten Agertoug, Barfod, Lea Klingenberg, Hviid, Lars, Salanti, Ali, Lavstsen, Thomas & Wang, Kaituo, 2022, In: PLoS Pathogens. 18, 11, e1010924.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma antibodies from malaria-exposed pregnant women recognize variant surface antigens on Plasmodium falciparum-infected erythrocytes in a parity-dependent manner and block parasite adhesion to chondroitin sulfate A
Ricke, C. H., Staalsoe, T., Koram, K., Akanmori, B. D., Riley, E. M., Theander, Thor Grundtvig & Hviid, Lars, 2000, In: Journal of Immunology. 165, 6, p. 3309-16 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Malaria
Riley, E. M., Hviid, Lars & Theander, Thor Grundtvig, 1994, Parasitic infections and the immune system. San Diego: Academic Press, p. 119-143Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Malaria
Riley, E. M., Hviid, Lars & Theander, Thor Grundtvig, 22 Oct 2013, Parasitic Infections and the Immune System. Elsevier Science Inc., p. 119-143 25 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Malaria in pregnancy: pathogenesis and immunity
Rogerson, S. J., Hviid, Lars, Duffy, P. E., Leke, R. F. G. & Taylor, D. W., 2007, In: Lancet Infectious Diseases. 7, 2, p. 105-17 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Detection of very low level Plasmodium falciparum infections using the nested polymerase chain reaction and a reassessment of the epidemiology of unstable malaria in Sudan
Roper, C., Elhassan, I. M., Hviid, Lars, Giha, H., Richardson, W., Babiker, H., Satti, G. M., Theander, Thor Grundtvig & Arnot, D. E., 1996, In: American Journal of Tropical Medicine and Hygiene. 54, 4, p. 325-31 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Seasonal changes in the Plasmodium falciparum population in individuals and their relationship to clinical malaria: a longitudinal study in a Sudanese village
Roper, C., Richardson, W., Elhassan, I. M., Giha, H., Hviid, Lars, Satti, G. M., Theander, Thor Grundtvig & Arnot, D. E., 1998, In: Parasitology. 116 ( Pt 6), p. 501-10 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria
Salanti, Ali, Staalsoe, T., Lavstsen, Thomas, Jensen, Anja Ramstedt, Sowa, M. P. K., Arnot, D. E., Hviid, Lars & Theander, Thor Grundtvig, 2003, In: Molecular Microbiology. 49, 1, p. 179-91 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A sub-family of common and highly conserved Plasmodium falciparum var genes
Salanti, Ali, Jensen, Anja Ramstedt, Zornig, H. D., Staalsoe, T., Joergensen, L., Nielsen, Morten Agertoug, Khattab, A., Arnot, D. E., Klinkert, M. Q., Hviid, Lars & Theander, Thor Grundtvig, 2002, In: Molecular and Biochemical Parasitology. 122, 1, p. 111-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evidence for the involvement of VAR2CSA in pregnancy-associated malaria
Salanti, Ali, Dahlbäck, M., Turner, Louise, Nielsen, Morten Agertoug, Barfod, Lea Klingenberg, Magistrado, P., Jensen, Anja Ramstedt, Lavstsen, Thomas, Ofori, M. F., Marsh, K., Hviid, Lars & Theander, Thor Grundtvig, 2004, In: Journal of Experimental Medicine. 200, 9, p. 1197-203 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Clinical and laboratory characteristics of children with sickle cell disease on hydroxyurea treated with artemether-lumefantrine for acute uncomplicated malaria
Segbefia, C., Amponsah, S. K., Afrane, A. K. A., Nyarko, M. Y., Brew, Y., Salifu, N., Ahorhorlu, S. Y., Sulley, A. M., Hviid, Lars, Ofori, M. F. & Adjei, G. O., 2023, In: Frontiers in Medicine. 10, p. 1291330Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum infection and naturally acquired immunity to malaria antigens among Ghanaian children in northern Ghana
Seidu, Zakaria, Lamptey, H., Lopez-Perez, Mary, Whittle, N. O., Oppong, S. K., Kyei-Baafour, E., Pobee, A. N. A., Adjei, G. O., Hviid, Lars & Ofori, M. F., 2023, In: Parasite Epidemiology and Control. 22, p. e00317Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-activity studies: in vitro antileishmanial and antimalarial activities of anthraquinones from Morinda lucida
Sittie, A. A., Lemmich, E., Olsen, C. E., Hviid, Lars, Kharazmi, A., Nkrumah, F. K. & Christensen, Søren Brøgger, 1999, In: Planta Medica. 65, 3, p. 259-61 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Alkamides from Phyllanthus fraternus
Sittie, A. A., Lemmich, E., Olsen, C. E., Hviid, Lars & Christensen, Søren Brøgger, 1998, In: Planta Medica. 64, 2, p. 192-3 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites
Sleebs, B. E., Lopaticki, S., Marapana, D. S., O'Neill, M. T., Rajasekaran, P., Gazdik, M., Günther, S., Whitehead, L. W., Lowes, K. N., Barfod, Lea Klingenberg, Hviid, Lars, Shaw, P. J., Hodder, A. N., Smith, B. J., Cowman, A. F. & Boddey, J. A., 2014, In: P L o S Biology. 12, 7, p. e1001897Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reliable cell and tissue morphology-based diagnosis of endemic Burkitt lymphoma in resource-constrained settings in Ghana
Smith-Togobo, C., Pedersen, Mette Ølgod, Jensen, S. G., Duduyemi, B., Gyasi, R. K., Ofori, M. F., Paintsil, V., Renner, L., Nørgaard, P. & Hviid, Lars, 2019, In: BMC Cancer. 19, 7 p., 1270.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High frequencies of tumor-infiltrating and circulating γδ T cells in endemic Burkitt lymphoma patients
Smith-Togobo, C., Quintana Varon, Maria del Pilar, Ofori, M. F. & Hviid, Lars, 2019, In: American Journal of Tropical Medicine and Hygiene. 101, S5, p. 563-563 1830.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Human monoclonal IgG selection of Plasmodium falciparum for the expression of placental malaria-specific variant surface antigens
Soerli, J., Barfod, Lea Klingenberg, Lavstsen, Thomas, Bernasconi, N. L., Lanzavecchia, A. & Hviid, Lars, 2009, In: Parasite Immunology. 31, 6, p. 341-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of variant-specific immunity in asymptomatic malaria infections: maintaining a fine balance
Staalsoe, T. & Hviid, Lars, 1998, In: Trends in Parasitology. 14, 5, p. 177-8 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acquisition and decay of antibodies to pregnancy-associated variant antigens on the surface of Plasmodium falciparum-infected erythrocytes that protect against placental parasitemia
Staalsoe, T., Megnekou, R., Fievét, N., Ricke, C. H., Zornig, H. D., Leke, R., Taylor, D. W., Deloron, P. & Hviid, Lars, 2001, In: Journal of Infectious Diseases. 184, 5, p. 618-26 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection of antibodies to variant antigens on Plasmodium falciparum-infected erythrocytes by flow cytometry
Staalsoe, T., Giha, H. A., Dodoo, D., Theander, Thor Grundtvig & Hviid, Lars, 1999, In: Cytometry. Part B: Clinical Cytometry. 35, 4, p. 329-36 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel Plasmodium falciparum malaria vaccines: evidence-based searching for variant surface antigens as candidates for vaccination against pregnancy-associated malaria
Staalsoe, T., Jensen, Anja Ramstedt, Theander, Thor Grundtvig & Hviid, Lars, 2002, In: Immunology Letters. 84, 2, p. 133-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intermittent preventive sulfadoxine-pyrimethamine treatment of primigravidae reduces levels of plasma immunoglobulin G, which protects against pregnancy-associated Plasmodium falciparum malaria
Staalsoe, T., Shulman, C. E., Dorman, E. K., Kawuondo, K., Marsh, K. & Hviid, Lars, 2004, In: Infection and Immunity. 72, 9, p. 5027-30 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro selection of Plasmodium falciparum 3D7 for expression of variant surface antigens associated with severe malaria in African children
Staalsoe, T., Nielsen, Morten Agertoug, Vestergaard, L. S., Jensen, Anja Ramstedt, Theander, Thor Grundtvig & Hviid, Lars, 2003, In: Parasite Immunology. 25, 8-9, p. 421-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variant surface antigen-specific IgG and protection against clinical consequences of pregnancy-associated Plasmodium falciparum malaria
Staalsoe, T., Shulman, C. E., Bulmer, J. N., Kawuondo, K., Marsh, K. & Hviid, Lars, 2004, In: Lancet. 363, 9405, p. 283-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo switching between variant surface antigens in human Plasmodium falciparum infection
Staalsoe, T., Hamad, A. A., Hviid, Lars, Elhassan, I. M., Arnot, D. E. & Theander, Thor Grundtvig, 2002, In: Journal of Infectious Diseases. 186, 5, p. 719-22 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Kinetics of B Cell responses to Plasmodium falciparum erythrocyte membrane protein 1 in Ghanaian women naturally exposed to malaria parasites
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Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites
Research output: Contribution to journal › Journal article › Research › peer-review
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B-cell responses to pregnancy-restricted and -unrestricted Plasmodium falciparum erythrocyte membrane protein 1 antigens in Ghanaian women naturally exposed to malaria parasites
Research output: Contribution to journal › Journal article › Research › peer-review
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