Jens Lykkesfeldt
Professor
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Inner histopathologic changes and disproportionate zone volumes in foetal growth plates following gestational hypoglycaemia in rats
Jensen, Vivi Flou Hjorth, Mølck, A., Bøgh, I. B., Nowak, J., Viuff, B. M., Rasmussen, C. L. M., Voetmann, Louise Marie, Fels, J. J., Madsen, S. H., McGuigan, F. E., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Akesson, K. E., 2020, In: Scientific Reports. 10, 1, 13 p., 5609.Research output: Contribution to journal › Journal article › Research › peer-review
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Toxicological Effects during and following Persistent Insulin-Induced Hypoglycaemia in Healthy Euglycaemic Rats
Jensen, Vivi Flou Hjorth, Molck, A., Berthelsen, L. O., Alifrangis, L., Andersen, L., Chapman, M., Lykkesfeldt, Jens & Bogh, I. B., Jul 2017, In: Basic & Clinical Pharmacology & Toxicology. 121, 1, p. 53-66Research output: Contribution to journal › Journal article › Research › peer-review
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Chronic Hyperinsulinaemic Hypoglycaemia in Rats Is Accompanied by Increased Body Weight, Hyperleptinaemia, and Decreased Neuronal Glucose Transporter Levels in the Brain
Jensen, Vivi Flou Hjorth, Molck, A., Chapman, M., Alifrangis, L., Andersen, L., Lykkesfeldt, Jens & Bogh, I. B., 2017, In: International Journal of Endocrinology. 2017, 14 p., 7861236.Research output: Contribution to journal › Journal article › Research › peer-review
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Proximal Neuropathy and Associated Skeletal Muscle Changes Resembling Denervation Atrophy in Hindlimbs of Chronic Hypoglycaemic Rats
Jensen, Vivi Flou Hjorth, Molck, A. M., Soeborg, H., Nowak, J., Chapman, M., Lykkesfeldt, Jens & Bogh, I. B., Jan 2018, In: Basic & Clinical Pharmacology & Toxicology. 122, 1, p. 165-175Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of maternal hypoglycaemia during gestation on materno-foetal nutrient transfer and embryo-foetal development: Evidence from experimental studies focused primarily on the rat
Jensen, Vivi Flou Hjorth, Mølck, A. M., Lykkesfeldt, Jens & Bøgh, I. B., Apr 2018, In: Reproductive Toxicology. 77, p. 1-24 24 p.Research output: Contribution to journal › Review › Research › peer-review
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Prolonged insulin-induced hypoglycaemia reduces ß-cell activity rather than number in pancreatic islets in non-diabetic rats
Jensen, Vivi Flou Hjorth, Mølck, A. M., Nowak, J., Fels, J. J., Lykkesfeldt, Jens & Bøgh, I. B., 2022, In: Scientific Reports. 12, 14113.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of insulin-induced hypoglycaemia on the peripheral nervous system: focus on adaptive mechanisms, pathogenesis and histopathological changes
Jensen, Vivi Flou Hjorth, Mølck, A., Bøgh, I. B. & Lykkesfeldt, Jens, 2014, In: Journal of Neuroendocrinology. 26, 8, p. 482-496 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Importance of gestational hypoglycaemia for foetal malformations and skeletal development in rats
Jensen, Vivi Flou Hjorth, Mølck, A. M., Lykkesfeldt, Jens, Fels, J. J., Andersen, L., Renaut, R., McGuigan, F., Åkesson, K. E. & Bøgh, I. B., 2020, In: Reproductive Toxicology. 91, p. 14-26 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of insulin-induced hypoglycaemia on the central nervous system: evidence from experimental studies
Jensen, Vivi Flou Hjorth, Bøgh, I. B. & Lykkesfeldt, Jens, 2014, In: Journal of Neuroendocrinology. 26, 3, p. 123-150 28 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Histopathological nerve and skeletal muscle changes in rats subjected to persistent insulin-induced hypoglycemia
Jensen, Vivi Flou Hjorth, Mølck, A., Heydenreich, A., Jensen, K. J., Bertelsen, L. O., Alifrangis, L., Andersen, L., Søeborg, H., Chapman, M., Lykkesfeldt, Jens & Bøgh, I. B., Jan 2016, In: Toxicologic Pathology. 29, 1, p. 17-30 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Assessment of implantable infusion pumps for continuous infusion of human insulin in rats: potential for group housing
Jensen, Vivi Flou Hjorth, Molck, A., Martensson, M., Strid, M. A., Chapman, M., Lykkesfeldt, Jens & Bogh, I. B., 2017, In: Laboratory Animals. 51, 3, p. 273-283Research output: Contribution to journal › Journal article › Research › peer-review
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Gamma-tocopherol supplementation inhibits protein nitration and ascorbate oxidation in rats with inflammation
Jiang, Q., Lykkesfeldt, Jens, Shigenaga, M. K., Shigeno, E. T., Christen, S. & Ames, B. N., 2002, In: Free Radical Biology & Medicine. 33, 11, p. 1534-1542 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oxidative costs of reproduction in mouse strains selected for different levels of food intake and which differ in reproductive performance
Jothery, A. H. A., Vaanholt, L. M., Mody, N., Arnous, A., Lykkesfeldt, Jens, Bunger, L., Hill, W. G., Mitchell, S. E., Allison, D. B. & Speakman, J. R., 14 Nov 2016, In: Scientific Reports. 6, 12 p., 36353 .Research output: Contribution to journal › Journal article › Research › peer-review
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Is Diabetes Associated with Lower Vitamin C Status in Pregnant Women? A Prospective Study
Juhl, B., Lauszus, F. F. & Lykkesfeldt, Jens, Oct 2016, In: International Journal for Vitamin and Nutrition Research. 86, 5-6, p. 184-189Research output: Contribution to journal › Journal article › Research › peer-review
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Poor vitamin C status late in pregnancy is associated with increased risk of complications in type 1 diabetic women: A cross-sectional study
Juhl, B., Lauszus, F. F. & Lykkesfeldt, Jens, 2017, In: Nutrients. 9, 3, 9 p., 186.Research output: Contribution to journal › Journal article › Research › peer-review
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Glycemic control during pregnancy — A predictor of vitamin C status at labor in type 1 diabeticwomen?
Juhl, B., Lauszus, F. F. & Lykkesfeldt, Jens, 2019, In: Antioxidants. 8, 6, 153.Research output: Contribution to journal › Journal article › Research › peer-review
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Asymmetric dimethylarginine in somatically healthy schizophrenia patients treated with atypical antipsychotics: a case-control study
Jørgensen, Anders, Knorr, Ulla Benedichte Søsted, Soendergaard, M. G., Lykkesfeldt, Jens, Fink-Jensen, Anders, Poulsen, Henrik Enghusen, Jørgensen, Martin Balslev, Olsen, N. V. & Staalsø, J. M., 2015, In: B M C Psychiatry. 15, 8 p., 67.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased systemic oxidatively generated DNA and RNA damage in schizophrenia
Jørgensen, A., Brødbæk, K., Fink-Jensen, Anders, Knorr, U., Greisen Søndergaard, M., Henriksen, T., Weimann, A., Jepsen, P., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen & Jørgensen, Martin Balslev, 2013, In: Psychiatry Research. 209, 3, p. 417–423 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dietary Intervention Accelerates NASH Resolution Depending on Inflammatory Status with Minor Additive Effects on Hepatic Injury by Vitamin E Supplementation
Klaebel, J. H., Rakipovski, G., Andersen, B., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2020, In: Antioxidants. 9, 9, 808.Research output: Contribution to journal › Journal article › Research › peer-review
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Atorvastatin and vitamin e accelerates NASH resolution by dietary intervention in a preclinical guinea pig model
Klaebel, J. H., Skjødt, M., Skat-Rørdam, Josephine, Rakipovski, G., Ipsen, David Højland, Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Nutrients. 11, 11, 20 p., 2834.Research output: Contribution to journal › Journal article › Research › peer-review
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Efficacy of fibroblast growth factor 21 in non-alcoholic fatty liver disease in guinea pigs
Klaebel, J. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2022, In: Basic & Clinical Pharmacology & Toxicology. 130, 3, p. 385-393Research output: Contribution to journal › Journal article › Research › peer-review
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Differential toxicological response to positively and negatively charged nanoparticles in the rat brain
Knudsen, K. B., Northeved, H., Ek, P. K., Permin, A., Andresen, T. L., Larsen, S., Wegener, K. M., Lam, H. R. & Lykkesfeldt, Jens, 2014, In: Nanotoxicology. 8, 7, p. 764-774 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats
Knudsen, K. B., Northeved, H., Gjetting, T., Permin, A., Andresen, T. L., Wegener, K. M., Rye Lam, H. & Lykkesfeldt, Jens, 2014, In: Journal of Nanoparticle Research. 16, 1, 11 p., 2221.Research output: Contribution to journal › Journal article › Research › peer-review
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In vivo toxicity of cationic micelles and liposomes
Knudsen, K. B., Northeved, H., Kumar Ek, P., Permin, A., Gjetting, T., Andresen, T. L., Larsen, S., Wegener, K. M., Lykkesfeldt, Jens, Jantzen, K., Loft, Steffen, Møller, Peter & Roursgaard, Martin, 25 Feb 2015, In: Nanomedicine: Nanotechnology, Biology and Medicine. 11, 2, p. 467-477 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Expression of endothelin type B receptors (EDNRB) on smooth muscle cells is controlled by ternary complex factors and the actin cytoskeleton
Krawczyk, K. K., Skovsted, Gry Freja, Perisic, L., Rippe, C., Dreier, R., Berg, J. O., Lykkesfeldt, Jens, Hedin, U. & Sward, K., Apr 2018.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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No effect of melatonin on oxidative stress after laparoscopic cholecystectomy: a randomized placebo-controlled trial
Kücükakin, B., Klein, M., Lykkesfeldt, Jens, Reiter, R. J., Rosenberg, J. & Gögenür, I., 2010, In: Acta Anaesthesiologica Scandinavica. 54, 9, p. 1121-1127 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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No effect of melatonin to modify surgical-stress response after major vascular surgery: a randomised placebo-controlled trial
Kücükakin, B., Wilhelmsen, M., Lykkesfeldt, Jens, Reiter, R. J., Rosenberg, J. & Gögenur, I., 2010, In: European Journal of Vascular and Endovascular Surgery. 40, 4, p. 461-467 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Storage-induced increase in biomarkers of oxidative stress and inflammation in red blood cell components
Kücükakin, B., Kocak, V., Lykkesfeldt, Jens, Nielsen, H. J., Magnussen, K., Rosenberg, Jacob & Gögenür, I., 2011, In: Scandinavian Journal of Clinical & Laboratory Investigation. 71, 4, p. 299-303 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Utility of melatonin to treat surgical stress after major vascular surgery - a safety study
Kücükakin, B., Lykkesfeldt, Jens, Nielsen, H. J., Reiter, R. J., Rosenberg, Jacob & Gögenur, Ismail, 2008, In: Journal of Pineal Research. 44, 4, p. 426-431 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of two- and twelve-weeks sodium-glucose cotransporter 2 inhibition on DNA and RNA oxidation: two randomized, placebo-controlled trials
Larsen, E. L., Andersen, A., Kjær, L. K., Eickhoff, M. K., Frimodt-Møller, M., Persson, F., Rossing, Peter, Lykkesfeldt, Jens, Knop, Filip Krag, Vilsbøll, Tina, Rungby, Jørgen & Poulsen, Henrik Enghusen, 2023, In: Free Radical Research. 57, 2, p. 140-151Research output: Contribution to journal › Journal article › Research › peer-review
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Clarithromycin, trimethoprim, and penicillin and oxidative nucleic acid modifications in humans: randomised, controlled trials
Larsen, E. L., Cejvanovic, V., Kjær, L. K., Pedersen, M. T., Popik, S. D., Hansen, L. K., Andersen, Jon Thor Trærup, Solem, Espen Victor Jimenez, Broedbaek, K., Petersen, M., Weimann, A., Henriksen, T., Lykkesfeldt, Jens, Torp-Pedersen, C. & Poulsen, Henrik Enghusen, Aug 2017, In: British Journal of Clinical Pharmacology. 83, 8, p. 1643-1653Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of High Inspiratory Oxygen Fraction on Endothelial Dysfunction in Healthy Volunteers: A Randomized Controlled Cross-over Pilot Study
Larsen, M. H. H., Ekeløf, S., Kokotovic, D., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Gögenur, I., 2017, In: Anesthesia and Analgesia. 125, 5, p. 1793–1796Research output: Contribution to journal › Journal article › Research › peer-review
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Biochemical markers as indicators of the efficiency of antibiotic treatment of Actinobacillus pleuropneumoniae infection in pigs
Lauritsen, B., Lykkesfeldt, Jens, Angen, Ø. & Friis, C., 2000. 1 p.Research output: Contribution to conference › Paper › Research
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Evaluation of a single dose versus a divided dose regimen of danofloxacin in treatment of Actinobacillus pleuropneumoniae infection in pigs
Lauritzen, B., Lykkesfeldt, Jens & Friis, C., 2003, In: Research in Veterinary Science. 74, 3, p. 271-277 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Putative biomarkers for evaluating antibiotic treatment: an experimental model of porcine Actinobacillus pleuropneumoniae infection
Lauritzen, B., Lykkesfeldt, Jens, Skaanild, M. T., Angen, Ø., Nielsen, Jens Peter & Friis, C., 2003, In: Research in Veterinary Science. 74, 3, p. 261-270 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evaluation of a single dose and a split-dose regimen of danofloxacin against Actinobacillus pleuropneumoniae infection in pigs
Lauritzen, B., Lykkesfeldt, Jens & Friis, C., 2002.Research output: Contribution to conference › Paper › Research
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Evaluation of a single dose versus a divided dose regimen of amoxycillin in treatment of Actinobacillus pleuropneumoniae infection in pigs
Lauritzen, B., Lykkesfeldt, Jens & Friis, C., 2005, In: Research in Veterinary Science. 79, 1, p. 61-67 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biomarkers in evaluation of antibiotic treatment: an experimental model of porcine Actinobacillus pleuropneumoniae infection
Lauritzen, B., Lykkesfeldt, Jens, Angen, Ø., Nielsen, Jens Peter & Friis, C., 2002.Research output: Contribution to conference › Paper › Research
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Effects of heparin-binding protein (CAP37/azurocidin) in a porcine model of Actinobacillus pleuropneumoniae-induced pneumonia
Lauritzen, B., Lykkesfeldt, Jens, Djurup, R., Flodgaard, H. & Svendsen, O., 2005, In: Pharmacological Research. 51, 6, p. 509-514 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pasteurization Procedures for Donor Human Milk Affect Body Growth, Intestinal Structure, and Resistance against Bacterial Infections in Preterm Pigs
Li, Yanqi, Nguyen, Duc Ninh, de Waard, M., Christensen, Lars, Zhou, P., Jiang, Pingping, Sun, Jing, Bojesen, Anders Miki, Lauridsen, C., Lykkesfeldt, Jens, Dalsgaard, T. K., Bering, S. B. & Sangild, Per Torp, Jun 2017, In: Journal of Nutrition. 147, 6, p. 1121-1130Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation of vitamin C homeostasis during deficiency
Lindblad, M. M., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Nutrients. 5, 8, p. 2860-2879 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Validation of computed tomography as a diagnostic tool in guinea pigs with non-alcoholic fatty liver disease
Lintrup, K., Ipsen, David Højland, Skat-Rørdam, Josephine, Lykkesfeldt, Jens, Tveden-Nyborg, Pernille & Buelund, Lene Elisabeth, 2024, (E-pub ahead of print) In: Laboratory Animals.Research output: Contribution to journal › Journal article › Research › peer-review
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Göttingen minipig model of diet-induced atherosclerosis: influence of mild streptozotocin-induced diabetes on lesion severity and markers of inflammation evaluated in obese, obese and diabetic, and lean control animals
Ludvigsen, Trine Pagh, Kirk, R. K., Christoffersen, B. Ø., Pedersen, H. D., Martinussen, Torben, Kildegaard, J., Heegaard, P. M. H., Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2015, In: Journal of Translational Medicine. 13, 12 p., 312.Research output: Contribution to journal › Journal article › Research › peer-review
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Morphine concentration in plasma andcerebrospinal fluid in the anaesthetised pig after a single intravenous administration
Lykkegaard, K., Lykkesfeldt, Jens & Svendsen, O., 2000. 1 p.Research output: Contribution to conference › Paper › Research
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Morphine reduces spinal c-fos expression dose-dependently during experimental laparotomy in pigs: a combined pharmacokinetic and surgical study
Lykkegaard, K., Lykkesfeldt, Jens, Lauritzen, B. & Svendsen, O., 2008, In: Research in Veterinary Science. 84, 3, p. 457-464 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of smoking cessation on plasma ascorbic acid concentration
Lykkesfeldt, Jens, Priemé, H., Loft, Steffen & Poulsen, Henrik Enghusen, 13 Jul 1996, In: B M J (Clinical Research Edition). 313, 7049, p. 91Research output: Contribution to journal › Journal article › Research › peer-review
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Determination of ascorbic acid and dehydroascorbic acid in biological samples by high-performance liquid chromatography using subtraction methods: reliable reduction with tris[2-carboxyethyl]phosphine hydrochloride
Lykkesfeldt, Jens, 2000, In: Analytical Biochemistry. 282, p. 89-93 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Measurement of ascorbic acid and dehydroascorbic acid in biological samples
Lykkesfeldt, Jens, 2002, Current protocols in toxicology. Maines, M., Costa, L. G., Hodson, E., Reed, D. J. & Sipes, I. G. (eds.). New York: Wiley, p. 7.6.1-7.6.15 15 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Ascorbic acid recycling in human erythrocytes is induced by smoking in vivo
Lykkesfeldt, Jens, Viscovich, M. & Poulsen, H. E., 2003, In: Free Radical Biology & Medicine. 11, 11, p. 1439-1447 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma malondialdehyde is induced by smoking: a study with balanced antioxidant profiles
Lykkesfeldt, Jens, Viscovich, M. & Poulsen, H. E., 2004, In: British Journal of Nutrition. 92, 2, p. 203-206 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbic acid recycling in rat hepatocytes as measurement of antioxidant capacity: decline with age
Lykkesfeldt, Jens & Ames, B. N., 1999, Oxidants and antioxidants part A. Packer, L. (ed.). San Diego: Academic Press, Vol. 299. p. 83-88 6 p. (Methods in Enzymology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Increased oxidative damage in vitamin C deficiency is accompanied by induction of ascorbic acid recycling capacity in young but not mature guinea pigs
Lykkesfeldt, Jens, 2002, In: Free Radical Research. 36, 5, p. 567-574 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Determination of malondialdehyde as dithiobarbituric acid adduct in biological samples by HPLC with fluorescence detection: comparison with ultraviolet-visible spectrophotometry
Lykkesfeldt, Jens, 2001, In: Clinical Chemistry. 47, 9, p. 1725-1727 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbic acid recycling in rat hepatocytes as measurement of antioxidant capacity: decline with age
Lykkesfeldt, Jens & Ames, B. N., 1999, In: Methods in Enzymology. 299, p. 83-88 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbate is depleted by smoking and repleted by moderate supplementation: a study in male smokers and nonsmokers with matched dietary antioxidant intakes
Lykkesfeldt, Jens, Christen, S., Wallock, L. M., Chang, H. H., Jacob, R. A. & Ames, B. N., 2000, In: American Journal of Clinical Nutrition. 71, p. 530-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nitrosamindannende håndkøbspraeparater?
Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 13 Dec 1993, In: Ugeskrift for Laeger. 155, 50, p. 4106-4107 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Age-associated decline in ascorbic acid concentration, recycling, and biosynthesis in rat hepatocytes: reversal with (R)-alfa-lipoic acid supplementation
Lykkesfeldt, Jens, Hagen, T. M., Vinarsky, V. & Ames, B. N., 1998, In: The FASEB Journal. 12, p. 1183-1189 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Simultaneous determination of urinary free cortisol and 6*Gb-hydroxycortisol by high-performance liquid chromatography to measure human CYP3A activity
Lykkesfeldt, Jens, Loft, Steffen & Poulsen, Henrik Enghusen, 1994, In: Journal of Chromatography B: Biomedical Sciences and Applications. 660, p. 23-29Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbate and dehydroascorbic acid as reliable biomarkers of oxidative stress: analytical reproducibility and long-term stability of plasma samples subjected to acidic deproteinization
Lykkesfeldt, Jens, 2007, In: Cancer Epidemiology, Biomarkers & Prevention. 16, 11, p. 2513-2516 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Vitamin C
Lykkesfeldt, Jens & Carr, A. C., Jan 2024, In: Advances in Nutrition. 15, 1, 100155.Research output: Contribution to journal › Journal article › Research › peer-review
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Reply to Hemilä by Lykkesfeldt and Poulsen
Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2011, In: British Journal of Nutrition. 105, 3, p. 488 1 p.Research output: Contribution to journal › Letter › Research › peer-review
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Vitamin C: as biomarker and treatment of oxidative stress caused by smoking : methodological and clinical studies
Lykkesfeldt, Jens, 2005, Copenhagen: Center for Skov, Landskab og Planlægning/Københavns Universitet. 59 p.Research output: Book/Report › Doctoral thesis › Research
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Effect of smoking on erythorbic acid pharmacokinetics
Lykkesfeldt, Jens, Bolbjerg, M. L. & Poulsen, H. E., 2003, In: British Journal of Nutrition. 89, 5, p. 667-671 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbic acid and dehydroascorbic acid as biomarkers of oxidative stress caused by smoking, 1-3
Lykkesfeldt, Jens, Loft, Steffen, Nielsen, J. B. & Poulsen, Henrik Enghusen, 1997, In: American Journal of Clinical Nutrition. 65, p. 959-963Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxidative stress and damage in liver, but not in brain, of Fischer 344 rats subjected to dietary iron supplementation with lipid-soluble[(3,5,5-Trimethylhexanoyl)ferrocene]
Lykkesfeldt, Jens, Morgan, E., Christen, S., Skovgaard, L. T. & Moos, T., 2007, In: Journal of Biochemical and Molecular Toxicology (Print Edition). 21, 3, p. 145-155 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Simultaneous determination of urinary free cortisol and 6β-hydroxycortisol by high-performance liquid chromatography to measure human CYP3A activity
Lykkesfeldt, Jens, Loft, Steffen & Poulsen, Henrik Enghusen, 3 Oct 1994, In: Journal of Chromatography B: Biomedical Sciences and Applications. 660, 1, p. 23-29 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Determination of Ascorbic Acid and Dehydroascorbic Acid in Plasma by High-Performance Liquid Chromatography with Coulometric Detection - Are They Reliable Biomarkers of Oxidative Stress?
Lykkesfeldt, Jens, Loft, Steffen & Poulsen, Henrik Enghusen, 1995, In: Analytical Biochemistry. 229, p. 329-335Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ascorbate and dehydroascorbic acid as biomarkers of oxidative stress: validity of clinical data depends on vacutainer system used
Lykkesfeldt, Jens, 2012, In: Nutrition Research. 32, 1, p. 66-69 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxidants and antioxidants in disease: oxidative stress in farm animals
Lykkesfeldt, Jens & Svendsen, O., 2007, In: Veterinary Journal. 173, 3, p. 502-511 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Malondialdehyde as biomarker of oxidative damage to lipids caused by smoking: invited critical review
Lykkesfeldt, Jens, 2007, In: Clinica Chimica Acta. 380, 1-2, p. 50-58 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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On the effect of vitamin C intake on human health: How to (mis)interprete the clinical evidence
Lykkesfeldt, Jens, 2020, In: Redox Biology. 34, 13 p., 101532.Research output: Contribution to journal › Review › Research › peer-review
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The Pharmacokinetics of Vitamin C
Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Nutrients. 11, 10, 20 p., 2412.Research output: Contribution to journal › Review › Research › peer-review
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Synthesis of benzylglucosinolate in Tropaeolum majus L. Isothiocyanates as potent enzyme inhibitors
Lykkesfeldt, Jens & Møller, Birger Lindberg, 1 Jan 1993, In: Plant Physiology. 102, 2, p. 609-613 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Is vitamin C supplementation beneficial? lessons learned from randomised controlled trials
Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2010, In: British Journal of Nutrition. 103, 9, p. 1251-1259 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vitamin C
Lykkesfeldt, Jens, Michels, A. J. & Frei, B., 2014, In: Advances in Nutrition. 5, 1, p. 16-18 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Strategies for Using Plagiarism Software in the Screening of Incoming Journal Manuscripts: Recommendations Based on a Recent Literature Survey
Lykkesfeldt, Jens, Aug 2016, In: Basic & Clinical Pharmacology & Toxicology. 119, 2, p. 161-164Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vitamin C deficiency in weanling guinea pigs: differential expression of oxidative stress and DNA repair in liver and brain
Lykkesfeldt, Jens, Trueba, G. P., Poulsen, H. E. & Christen, S., 2007, In: British Journal of Nutrition. 98, 6, p. 1116-1119 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Age-dependent change in Vitamin C status: a phenomenon of matruration rather than of ageing
Lykkesfeldt, Jens & Moos, T., 2005, In: Mechanisms of Ageing and Development. 126, 8, p. 892-898 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does vitamin C matter? A quest for in vivo effects of vitamin C deficiency
Lykkesfeldt, Jens, 2008, In: Free Radical Research. 42, S1, p. s23 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Vitamin C pharmacokinetics*
Lykkesfeldt, Jens, 1 Jan 2020, Vitamin C: New Biochemical and Functional Insights. CRC Press, p. 55-70 16 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Vitamin C
Lykkesfeldt, Jens & Carr, A. C., Jan 2024, In: Advances in nutrition (Bethesda, Md.). 15, 1, p. 100155Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vitamin C – a scoping review for Nordic Nutrition Recommendations 2023
Lykkesfeldt, Jens & Carr, A. C., 2023, In: Food and Nutrition Research. 67, 19 p., 10300.Research output: Contribution to journal › Review › Research › peer-review
- Published
Ascorbic acid recycling in rat hepatocytes as measurement of antioxidant capacity: Decline with age
Lykkesfeldt, Jens & Ames, B. N., 3 Nov 1998, In: Methods in Enzymology. 299, p. 83-88 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Smoking depletes vitamin C: should smokers be recommended to take supplements?
Lykkesfeldt, Jens, 2006, Cigarette smoke and oxidative stress. Halliwell, B. B. & Poulsen, H. E. (eds.). Berlin: Kluwer Academic Publishers, p. 236-258 23 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Oxidative stress response after laparoscopic versus conventional sigmoid resection: a randomized, double-blind clinical trial
Madsen, M. T., Kücükakin, B., Lykkesfeldt, Jens, Rosenberg, J. & Gögenur, I., 2012, In: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques. 22, 3, p. 215-219 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Animal models in pharmacology and toxicology
Meyer, O. A., Svendsen, O. & Lykkesfeldt, Jens, 2011, Handbook of laboratory animal science: volume II: Animal models. Hau, J. & J. Schapiro, S. (eds.). 3. ed. ed. CRC Press, Vol. 2. p. 149-184 36 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
The role of vitamin C in epigenetic cancer therapy
Mikkelsen, Stine Ulrik, Gillberg, Linn, Lykkesfeldt, Jens & Grønbæk, Kirsten, 2021, In: Free Radical Biology and Medicine. 170, p. 179-193 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies
Mortensen, A. & Lykkesfeldt, Jens, 2014, In: Nitric Oxide: Biology and Chemistry. 36, p. 51-57 7 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Guinea pig ascorbate status predicts tetrahydrobiopterin plasma concentration and oxidation ratio in vivo
Mortensen, A., Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Nutrition Research. 33, 10, p. 859-867 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinetics of acid-induced degradation of tetra- and dihydrobiopterin in relation to their relevance as biomarkers of endothelial function
Mortensen, A. & Lykkesfeldt, Jens, 2013, In: Biomarkers. 18, 1, p. 55-62 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lower Vitamin C Levels Are Associated With Less Improvement in Negative Symptoms in Initially Antipsychotic-Naïve Patients With First-Episode Psychosis
Myken, A. N., Ebdrup, Bjørn, Sørensen, M. E., Broberg, B. V., Skjerbæk, M. W., Glenthøj, Birte Yding, Lykkesfeldt, Jens & Nielsen, Mette Ødegaard, 2022, In: The international journal of neuropsychopharmacology. 25, 8, p. 613-618 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vitamin C supplementation decreases oxidative DNA damage in mononuclear bood cells of smokers
Møller, P., Viscovich, M., Lykkesfeldt, Jens, Loft, S., Jensen, A. & Poulsen, H. E., 2004, In: European Journal of Nutrition. 43, p. 267-274 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Positive charge, negative effect: the impact of cationic nanoparticles in the brain
Møller, Peter & Lykkesfeldt, Jens, Jul 2014, In: Nanomedicine. 9, 10, p. 1441-3 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Heterozygous mutations in GTP-cyclohydrolase-1 reduce BH4 biosynthesis but not pain sensitivity
Nasser, A., Møller, A. T., Hellmund, V., Thorborg, S. S., Jespersgaard, C., Bjerrum, Ole Jannik, Dupontd, E., Nachman, G., Lykkesfeldt, Jens, Jensen, T. S. & Møller, L. B., 2018, In: Pain. 159, 6, p. 1012-1024 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Weekly ascorbic acid infusion in castration-resistant prostate cancer patients: A single-arm phase II trial
Nielsen, Torben Kjær, Højgaard, M., Andersen, Jon Thor Trærup, Jørgensen, N. R., Zerahn, B., Kristensen, B., Henriksen, T., Lykkesfeldt, Jens, Mikines, K. J. & Poulsen, Henrik Enghusen, 2017, In: Translational Andrology and Urology. 6, 3, p. 517-528 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elimination of ascorbic acid after high-dose infusion in prostate cancer patients: a pharmacokinetic evaluation
Nielsen, Torben Kjær, Højgaard, M., Andersen, J. T. T., Poulsen, Henrik Enghusen, Lykkesfeldt, Jens & Mikines, K. J., 2015, In: Basic & Clinical Pharmacology & Toxicology. 116, 4, p. 343-348 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Translational aspects of rectal evoked potentials: a comparative study in rats and humans
Nissen, T. D., Brock, C., Graversen, C., J. Coen, S., Hultin, L., Aziz, Q., Lykkesfeldt, Jens & Drewes, A. M., 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 305, p. G119-G128 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacological modulation of colorectal distension evoked potentials in conscious rats
Nissen, T. D., Brock, C., Lykkesfeldt, Jens, Lindström, E. & Hultin, L., 2018, In: Neuropharmacology. 140, p. 193-200 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Poor vitamin C status is associated with increased carotid intima-media thickness, decreased microvascular function, and delayed myocardial repolarization in young patients with type 1 diabetes
Odermarsky, M., Lykkesfeldt, Jens & Liuba, P., 2009, In: American Journal of Clinical Nutrition. 90, 2, p. 447-452 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Carotid Artery Intima-Media Thickness and Cutaneous Microvascular Function are Associated With Vitamin C Levels in Young Patients With Type 1 Diabetes
Odermarsky, M., Lykkesfeldt, Jens & Liuba, P., 2008, Scientific Sessions 2008.Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research
ID: 4231856
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Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats
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Increased systemic oxidatively generated DNA and RNA damage in schizophrenia
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Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies
Research output: Contribution to journal › Review › Research › peer-review
Published