Yen-Hsi Chen

Yen-Hsi Chen

Guest Researcher


Publication year:
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1 - 10 out of 17Page size: 10
  1. 2024
  2. Published

    Tumor-agnostic cancer therapy using antibodies targeting oncofetal chondroitin sulfate

    Vidal-Calvo, E. E., Martin-Salazar, A., Choudhary, S., Dagil, R., Raghavan, S. S. R., Duvnjak, L., Nordmaj, M. A., Clausen, T. M., Skafte, A., Oberkofler, J., Wang, K., Agerbæk, M. Ø., Løppke, C., Jørgensen, A. M., Ropac, D., Mujollari, J., Willis, S., Garcias López, A., Miller, R. L., Karlsson, R. T. G. & 21 others, Goerdeler, Felix Tobias Reinhard, Chen, Yen-Hsi, Colaço, A. R., Wang, Y., Lavstsen, Thomas, Martowicz, A., Nelepcu, I., Marzban, M., Oo, H. Z., Ørum-Madsen, M. S., Wang, Y., Nielsen, Morten Agertoug, Clausen, Henrik, Wierer, M., Wolf, D., Gögenur, Ismail, Theander, Thor Grundtvig, Al-Nakouzi, N., Gustavsson, Tobias, Daugaard, M. & Salanti, Ali, 2024, In: Nature Communications. 15, 1, 20 p., 7553.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2023
  4. Published

    A universal GlycoDesign for lysosomal replacement enzymes to improve circulation time and biodistribution

    Chen, Yen-Hsi, Tian, W., Yasuda, M., Ye, Z., Song, Ming, Mandel, Ulla, Kristensen, C., Povolo, Lorenzo, Marques, A. R. A., Čaval, T., Heck, A. J. R., Sampaio, J. L., Johannes, L., Tsukimura, T., Desnick, R., Vakhrushev, Sergey, Yang, Zhang & Clausen, Henrik, 2023, In: Frontiers in Bioengineering and Biotechnology. 11, 1128371.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Glycoengineered keratinocyte library reveals essential functions of specific glycans for all stages of HSV-1 infection

    Bagdonaite, Ieva , Marinova, I. N., Levann, Asha Maria Rudjord, Pallesen, E. M. H., King-Smith, S. L., Karlsson, R., Rømer, T. B., Chen, Yen-Hsi, Miller, Rebecca Louise, Olofsson, S., Nordén, R., Bergström, T., Dabelsteen, Sally & Wandall, Hans H., 2023, In: Nature Communications. 14, 19 p., 7000.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2022
  7. Published

    Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 by Disrupting the Spike-ACE2 Interaction

    Guimond, S. E., Mycroft-West, C. J., Gandhi, N. S., Tree, J. A., Le, T. T., Spalluto, C. M., Humbert, M. V., Buttigieg, K. R., Coombes, N., Elmore, M. J., Wand, M., Nyström, K., Said, J., Setoh, Y. X., Amarilla, A. A., Modhiran, N., Sng, J. D. J., Chhabra, M., Young, P. R., Rawle, D. J. & 22 others, Lima, M. A., Yates, E. A., Karlsson, R., Miller, Rebecca Louise, Chen, Yen-Hsi, Bagdonaite, Ieva , Yang, Zhang, Stewart, J., Nguyen, D., Laidlaw, S., Hammond, E., Dredge, K., Wilkinson, T. M. A., Watterson, D., Khromykh, A. A., Suhrbier, A., Carroll, M. W., Trybala, E., Bergström, T., Ferro, V., Skidmore, M. A. & Turnbull, Jeremy Ewan, 2022, In: ACS Central Science. 8, 5, p. 527-545 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 2021
  9. Published

    Dissecting structure-function of 3-O-sulfated heparin and engineered heparan sulfates

    Karlsson, R., Chopra, P., Joshi, A., Yang, Zhang, Vakhrushev, Sergey, Clausen, Thomas Mandel, Painter, C. D., Szekeres, G. P., Chen, Yen-Hsi, Sandoval, D. R., Hansen, Lars, Esko, J. D., Pagel, K., Dyer, D. P., Turnbull, Jeremy Ewan, Clausen, Henrik, Boons, G. J. & Miller, Rebecca Louise, 2021, In: Science Advances. 7, 52, eabl6026.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Evidence of a putative glycosaminoglycan binding site on the glycosylated SARS-CoV-2 spike protein N-terminal domain

    Schuurs, Z. P., Hammond, E., Elli, S., Rudd, T. R., Mycroft-West, C. J., Lima, M. A., Skidmore, M. A., Karlsson, R., Chen, Yen-Hsi, Bagdonaite, Ieva , Yang, Zhang, Ahmed, Y. A., Richard, D. J., Turnbull, Jeremy Ewan, Ferro, V., Coombe, D. R. & Gandhi, N. S., 2021, In: Computational and Structural Biotechnology Journal. 19, p. 2806-2818 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Genetic glycoengineering in mammalian cells

    Narimatsu, Yoshiki, Büll, C., Chen, Yen-Hsi, Wandall, Hans H., Yang, Zhang & Clausen, Henrik, 2021, In: Journal of Biological Chemistry. 296, 25 p., 100448.

    Research output: Contribution to journal › Review › Research › peer-review

  12. Published

    The C-terminal peptide of CCL21 drastically augments CCL21 activity through the dendritic cell lymph node homing receptor CCR7 by interaction with the receptor N-terminus

    Jørgensen, Astrid Sissel, Brandum, E. P., Mikkelsen, J. M., Orfin, K. A., Boilesen, D. R., Egerod, Kristoffer Lihme, Moussouras, N. A., Vilhardt, Frederik, Kalinski, P., Basse, P., Chen, Yen-Hsi, Yang, Zhang, Dwinell, M. B., Volkman, B. F., Veldkamp, C. T., Holst, Peter Johannes, Lahl, K., Goth, C. K., Rosenkilde, Mette & Hjortø, Gertrud Malene, 2021, In: Cellular and Molecular Life Sciences. 78, p. 6963-6978 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The Hyperlipidaemic Drug Fenofibrate Significantly Reduces Infection by SARS-CoV-2 in Cell Culture Models

    Davies, S. P., Mycroft-West, C. J., Pagani, I., Hill, H. J., Chen, Yen-Hsi, Karlsson, R., Bagdonaite, Ieva , Guimond, S. E., Stamataki, Z., De Lima, M. A., Turnbull, Jeremy Ewan, Yang, Zhang, Vicenzi, E., Skidmore, M. A., Khanim, F. L. & Richardson, A., 2021, In: Frontiers in Pharmacology. 12, 660490.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Unfractionated heparin inhibits live wild type SARS-CoV-2 cell infectivity at therapeutically relevant concentrations

    Tree, J. A., Turnbull, Jeremy Ewan, Buttigieg, K. R., Elmore, M. J., Coombes, N., Hogwood, J., Mycroft-West, C. J., Lima, M. A., Skidmore, M. A., Karlsson, R., Chen, Yen-Hsi, Yang, Zhang, Spalluto, C. M., Staples, K. J., Yates, E. A., Gray, E., Singh, D., Wilkinson, T., Page, C. P. & Carroll, M. W., 2021, In: British Journal of Pharmacology. 178, 3, p. 626-635 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 126195133