Thor Grundtvig Theander
Professor
Centre for Medical Parasitology
Blegdamsvej 3, 2200 København N, Building: 07-11-17
CMP
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-11-TR4
Member of:
CMP-BIOENGINEERING
- Published
Molecular and immunological characterisation of the glucose regulated protein 78 of Leishmania donovani
Jensen, Anja Ramstedt, Curtis, J., Montgomery, J., Handman, E. & Theander, Thor Grundtvig, 2001, In: BBA General Subjects. 1549, 1, p. 73-87 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lack of gender-specific antibody recognition of products from domains of a var gene implicated in pregnancy-associated Plasmodium falciparum malaria
Jensen, Anja Ramstedt, Zornig, H. D., Buhmann, Cæcilie Christine Böck, Salanti, Ali, Koram, K. A., Riley, E. M., Theander, Thor Grundtvig, Hviid, Lars & Staalsoe, T., 2003, In: Infection and Immunity. 71, 7, p. 4193-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes
Jensen, Anja Ramstedt, Magistrado, P., Sharp, S., Joergensen, L., Lavstsen, Thomas, Chiucchiuini, A., Salanti, Ali, Vestergaard, L. S., Lusingu, J. P., Hermsen, R., Sauerwein, R., Christensen, J., Nielsen, Morten Agertoug, Hviid, Lars, Sutherland, C., Staalsoe, T. & Theander, Thor Grundtvig, 2004, In: Journal of Experimental Medicine. 199, 9, p. 1179-90 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Humoral and cellular immune responses to glucose regulated protein 78 - a novel Leishmania donovani antigen
Jensen, Anja Ramstedt, Ismail, A., Gaafar, A., El Hassan, A. M. & Theander, Thor Grundtvig, 2002, In: Tropical Medicine & International Health. 7, 5, p. 471-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum var genes expressed in children with severe malaria encode CIDRα1 domains
Jespersen, Jakob Schmidt, Wang, Christian William, Mkumbaye, S. I., Minja, D. T., Petersen, Bent, Turner, Louise, Petersen, J. E., Lusingu, J. P., Theander, Thor Grundtvig & Lavstsen, Thomas, 2016, In: EMBO Molecular Medicine. 8, 8, p. 839-850 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum
Jiang, L., Mu, J., Zhang, Q., Ni, T., Srinivasan, P., Rayavara, K., Yang, W., Turner, L., Lavstsen, T., Theander, T. G., Peng, W., Wei, G., Jing, Q., Wakabayashi, Y., Bansal, A., Luo, Y., Ribeiro, J. M. C., Scherf, A., Aravind, L., Zhu, J. & 2 others, , 11 Jul 2013, In: Nature. 499, 7457, p. 223-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The kinetics of antibody binding to Plasmodium falciparum VAR2CSA PfEMP1 antigen and modelling of PfEMP1 antigen packing on the membrane knobs
Joergensen, L. M., Salanti, Ali, Dobrilovic, T., Barfod, Lea Klingenberg, Hassenkam, Tue, Theander, Thor Grundtvig, Hviid, Lars & Arnot, D. E., 2010, In: Malaria Journal. 9, 1, p. 100Research output: Contribution to journal › Journal article › Research › peer-review
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Surface co-expression of two different PfEMP1 antigens on single Plasmodium falciparum-infected erythrocytes facilitates binding to ICAM1 and PECAM1
Joergensen, L., Bengtsson, D. C., Bengtsson, A., Ronander, E., Berger, S. S., Turner, Louise, Dalgaard, M. B., Cham, G. K. K., Victor, M. E., Lavstsen, Thomas, Theander, Thor Grundtvig, Arnot, D. E. & Jensen, Anja Ramstedt, 2010, In: PLoS Pathogens. 6, 9, p. e1001083Research output: Contribution to journal › Journal article › Research › peer-review
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3D7-derived Plasmodium falciparum erythrocyte membrane protein 1 is a frequent target of naturally acquired antibodies recognizing protein domains in a particular pattern independent of malaria transmission intensity
Joergensen, L., Vestergaard, L. S., Turner, Louise, Magistrado, P., Lusingu, J. P., Lemnge, M., Theander, Thor Grundtvig & Jensen, Anja Ramstedt, 2007, In: Journal of Immunology. 178, 1, p. 428-35 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Limited cross-reactivity among domains of the Plasmodium falciparum clone 3D7 erythrocyte membrane protein 1 family
Joergensen, L., Turner, Louise, Magistrado, P., Dahlbäck, M. A., Vestergaard, L. S., Lusingu, J. P., Lemnge, M., Salanti, Ali, Theander, Thor Grundtvig & Jensen, Anja Ramstedt, 2006, In: Infection and Immunity. 74, 12, p. 6778-84 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interferon-¿- and tumour necrosis factor-a-producing cells in humans who are immune to cutaneous leishmaniasis
Kemp, K., Theander, Thor Grundtvig, Hviid, Lars, Garfar, A., Kharazmi, A. & Kemp, M., 1999, In: Scandinavian Journal of Immunology. 49, 6, p. 655-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Leishmania-specific T cells expressing interferon-¿(IFN-¿) and IL-10 upon activation are expanded in individuals cured of visceral leishmaniasis
Kemp, K., Kemp, M., Kharazmi, A., Ismail, A., Kurtzhals, Jørgen, Hviid, Lars & Theander, Thor Grundtvig, 1999, In: Clinical and Experimental Immunology. 116, 3, p. 500-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dichotomy of the human T cell response to Leishmania antigens. I. Th1-like response to Leishmania major promastigote antigens in individuals recovered from cutaneous leishmaniasis
Kemp, M., Hey, A. S., Kurtzhals, Jørgen, Christensen, C. B., Gaafar, A., Mustafa, M. D., Kordofani, A. A., Ismail, A., Kharazmi, A. & Theander, Thor Grundtvig, 1994, In: Clinical and Experimental Immunology. 96, 3, p. 410-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The contrasting roles of CD4+ T cells in intracellular infections in humans: leishmaniasis as an example
Kemp, M., Theander, Thor Grundtvig & Kharazmi, A., 1996, In: Trends in Immunology. 17, 1, p. 13-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dichotomy in the human CD4+ T-cell response to Leishmania parasites
Kemp, M., Kurtzhals, Jørgen, Kharazmi, A. & Theander, Thor Grundtvig, 1994, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 102, 2, p. 81-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Activation of human T lymphocytes by Leishmania lipophosphoglycan
Kemp, M., Theander, Thor Grundtvig, Handman, E., Hey, A. S., Kurtzhals, Jørgen, Hviid, Lars, Sørensen, A. L., Were, J. O., Koech, D. K. & Kharazmi, A., 1991, In: Scandinavian Journal of Immunology. 33, 2, p. 219-24 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Leishmania donovani-reactive Th1- and Th2-like T-cell clones from individuals who have recovered from visceral leishmaniasis
Kemp, M., Kurtzhals, Jørgen, Bendtzen, K., Poulsen, L. K., Hansen, M. B., Koech, D. K., Kharazmi, A. & Theander, Thor Grundtvig, 1993, In: Infection and Immunity. 61, 3, p. 1069-73 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Leishmaniasis
Kemp, M. & Theander, Thor Grundtvig, 2000, In: Ugeskrift for læger. 162, 46, p. 6203-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Production of interferon-¿ and interleukin-4 by human T cells recognizing Leishmania lipophosphoglycan-associated protein
Kemp, M., Kurtzhals, Jørgen, Christensen, C. B., Kharazmi, A., Jardim, A., Bendtzen, K., Gachihi, G. S., Olafson, R. W. & Theander, Thor Grundtvig, 1993, In: Immunology Letters. 38, 2, p. 137-44 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Th1-like human T-cell clones recognizing Leishmania gp63 inhibit Leishmania major in human macrophages
Kemp, M., Hey, A. S., Bendtzen, K., Kharazmi, A. & Theander, Thor Grundtvig, 1994, In: Scandinavian Journal of Immunology. 40, 6, p. 629-35 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human infektionsimmunologi. Basalvidenskabelige opdagelser og kliniske konsekvenser
Kemp, M., Pedersen, Bente Klarlund & Theander, Thor Grundtvig, 2000, In: Ugeskrift for læger. 162, 21, p. 3020-3 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interferon-¿ and interleukin-4 in human Leishmania donovani infections
Kemp, M., Kurtzhals, Jørgen, Kharazmi, A. & Theander, Thor Grundtvig, 1993, In: Immunology and Cell Biology. 71 ( Pt 6), p. 583-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Leishmania promastigote surface antigen-2 (PSA-2) is specifically recognised by Th1 cells in humans with naturally acquired immunity to L. major
Kemp, M., Handman, E., Kemp, K., Ismail, A., Mustafa, M. D., Kordofani, A. Y., Bendtzen, K., Kharazmi, A. & Theander, Thor Grundtvig, 1998, In: FEMS Immunology and Medical Microbiology. 20, 3, p. 209-18 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Recognition of Leishmania antigens by T lymphocytes from nonexposed individuals
Kemp, M., Hansen, M. B. & Theander, Thor Grundtvig, 1992, In: Infection and Immunity. 60, 6, p. 2246-51 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Limonoids from Khaya senegalensis
Khalid, S., Friedrichsen, G., Kharazmi, A., Theander, Thor Grundtvig, Olsen, C. & Christensen, Søren Brøgger, 1998, In: Phytochemistry. 49, 6, p. 1769-1772 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The roles of the pfcrt 76T and pfmdr1 86Y mutations, immunity and the initial level of parasitaemia, in predicting the outcome of chloroquine treatment in two areas with different transmission intensities
Khalil, I. F., Alifrangis, Michael, Tarimo, D. S., Staalsø, T., Satti, G. M. H., Theander, Thor Grundtvig, Rønn, A. M. & Bygbjerg, Ib Christian, 2005, In: Annals of Tropical Medicine and Parasitology. 99, 5, p. 441-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Measurement of lumefantrine and its metabolite in plasma by high performance liquid chromatography with ultraviolet detection
Khalil, I. F., Abildrup, U., Alifrangis, L. H., Maiga, D., Alifrangis, Michael, Hoegberg, L., Vestergaard, L. S., Persson, O. P., Nyagonde, N., Lemnge, M. M., Theander, Thor Grundtvig & Bygbjerg, Ib Christian, 5 Jan 2011, In: Journal of Pharmaceutical and Biomedical Analysis. 54, 1, p. 168-72 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pseudomonas aeruginosa septicaemia in a patient with severe Plasmodium falciparum
Kharazmi, A., Høiby, Niels & Theander, Thor Grundtvig, 1987, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 81, 1, p. 49-50 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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T-cell response in human leishmaniasis
Kharazmi, A., Kemp, K., Ismail, A., Gasim, S., Gaafar, A., Kurtzhals, Jørgen, El Hassan, A. M., Theander, Thor Grundtvig & Kemp, M., 1999, In: Immunology Letters. 65, 1-2, p. 105-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Discovery of oxygentade chalcones as novel antimalarial agents
Kharazmi, A., Chen, M., Theander, Thor Grundtvig & Christensen, Søren Brøgger, 1997, In: Annals of Tropical Medicine and Parasitology. 91, SUPPL. 1, p. S91-S95Research output: Contribution to journal › Journal article › Research › peer-review
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Discovery of oxygenated chalcoes as novel antimalarial agents
Kharazmi, A., Chen, M., Theander, Thor Grundtvig & Christensen, Søren Brøgger, 1997, In: Annals of Tropical Medicine and Parasitology. 91, p. S91-S95 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Full-length recombinant Plasmodium falciparum VAR2CSA binds specifically to CSPG and induces potent parasite adhesion blocking antibodies
Khunrae, P., Dahlbäck, M., Nielsen, Morten Agertoug, Andersen, G., Ditlev, S. B., Resende, M., Pinto, V. V., Theander, Thor Grundtvig, Higgins, M. K. & Salanti, Ali, 2010, In: Journal of Molecular Biology. 397, p. 826-834Research output: Contribution to journal › Journal article › Research › peer-review
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Depressed natural killer cell activity in acute myocardial infarction
Klarlund, K., Pedersen, Bente Klarlund, Theander, Thor Grundtvig & Andersen, V., 1987, In: Clinical and Experimental Immunology. 70, 1, p. 209-16 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dichotomy of the human T cell response to Leishmania antigens. II. Absent or Th2-like response to gp63 and Th1-like response to lipophosphoglycan-associated protein in cells from cured visceral leishmaniasis patients
Kurtzhals, Jørgen, Hey, A. S., Jardim, A., Kemp, M., Schaefer, K. U., Odera, E. O., Christensen, C. B., Githure, J. I., Olafson, R. W. & Theander, Thor Grundtvig, 1994, In: Clinical and Experimental Immunology. 96, 3, p. 416-21 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interleukin-4 and interferon-¿ production by Leishmania stimulated peripheral blood mononuclear cells from nonexposed individuals
Kurtzhals, Jørgen, Kemp, M., Poulsen, L. K., Hansen, M. B., Kharazmi, A. & Theander, Thor Grundtvig, 1995, In: Scandinavian Journal of Immunology. 41, 4, p. 343-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cellular and humoral immune responses in a population from the Baringo District, Kenya to Leishmania promastigote lipophosphoglycan
Kurtzhals, Jørgen, Hey, A. S., Theander, Thor Grundtvig, Odera, E., Christensen, C. B., Githure, J. I., Koech, D. K., Schaefer, K. U., Handman, E. & Kharazmi, A., 1992, In: American Journal of Tropical Medicine and Hygiene. 46, 4, p. 480-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structural Conservation Despite Huge Sequence Diversity Allows EPCR Binding by the PfEMP1 Family Implicated in Severe Childhood Malaria
Lau, C. K. Y., Turner, Louise, Jespersen, Jakob Schmidt, Lowe, E. D., Petersen, Bent, Wang, Christian William, Petersen, J. E. V., Lusingu, J., Theander, Thor Grundtvig, Lavstsen, Thomas & Higgins, M. K., 14 Jan 2015, In: Cell Host & Microbe. 17, 1, p. 118-29 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sub-grouping of Plasmodium falciparum 3D7 var genes based on sequence analysis of coding and non-coding regions
Lavstsen, Thomas, Salanti, Ali, Jensen, Anja Ramstedt, Arnot, D. E. & Theander, Thor Grundtvig, 2003, In: Malaria Journal. 2, p. 27Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children
Lavstsen, Thomas, Turner, Louise, Saguti, F., Magistrado, P. A., Rask, T. S., Jespersen, Jakob Schmidt, Wang, Christian William, Berger, S. S., Baraka, V., Marquard, A. M., Seguin-Orlando, A., Willerslev, Eske, Gilbert, M Thomas P, Lusingu, J. P. A. & Theander, Thor Grundtvig, 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 26, p. E1791-E1800 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Expression of Plasmodium falciparum erythrocyte membrane protein 1 in experimentally infected humans
Lavstsen, Thomas, Magistrado, P., Hermsen, C. C., Salanti, Ali, Jensen, Anja Ramstedt, Sauerwein, R., Hviid, Lars, Theander, Thor Grundtvig & Staalsoe, T., 2005, In: Malaria Journal. 4, 1, p. 21Research output: Contribution to journal › Journal article › Research › peer-review
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Structure-guided identification of a family of dual receptor-binding PfEMP1 that is associated with cerebral malaria
Lennartz, F., Adams, Y., Bengtsson, A., Olsen, R. W., Turner, L., Ndam, N. T., Ecklu-Mensah, G. D., Moussiliou, A., Ofori, M. F., Gamain, B., Lusingu, J. P., Petersen, J. E. V., Wang, C. W., Nunes-Silva, S., Jespersen, J. S., Lau, C. K. Y., Theander, T. G., Lavstsen, T., Hviid, L., Higgins, M. K. & 1 others, , 8 Mar 2017, In: Cell Host & Microbe. 21, 3, p. 403-414 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Malaria morbidity and immunity among residents of villages with different Plasmodium falciparum transmission intensity in North-Eastern Tanzania
Lusingu, J. P. A., Vestergaard, L. S., Mmbando, B. P., Drakeley, C. J., Jones, C., Akida, J., Savaeli, Z. X., Kitua, A. Y., Lemnge, M. M. & Theander, Thor Grundtvig, 2004, In: Malaria Journal. 3, p. 26Research output: Contribution to journal › Journal article › Research › peer-review
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Cytophilic antibodies to Plasmodium falciparum glutamate rich protein are associated with malaria protection in an area of holoendemic transmission
Lusingu, J. P. A., Vestergaard, L. S., Alifrangis, Michael, Mmbando, B. P., Theisen, M., Kitua, A. Y., Lemnge, M. M. & Theander, Thor Grundtvig, 2005, In: Malaria Journal. 4, p. 48Research output: Contribution to journal › Journal article › Research › peer-review
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Levels of plasma immunoglobulin G with specificity against the cysteine-rich interdomain regions of a semiconserved Plasmodium falciparum erythrocyte membrane protein 1, VAR4, predict protection against malarial anemia and febrile episodes
Lusingu, J. P. A., Jensen, Anja Ramstedt, Vestergaard, L. S., Minja, D. T., Dalgaard, M. B., Gesase, S., Mmbando, B. P., Kitua, A. Y., Lemnge, M. M., Cavanagh, D., Hviid, Lars & Theander, Thor Grundtvig, 2006, In: Infection and Immunity. 74, 5, p. 2867-75 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vivo imaging of the buccal mucosa shows loss of the endothelial glycocalyx and perivascular hemorrhages in pediatric Plasmodium falciparum malaria
Lyimo, E., Haslund, L. E., Ramsing, T., Wang, Christian William, Efunshile, A. M., Manjurano, A., Makene, V., Lusingu, J., Theander, Thor Grundtvig, Kurtzhals, Jørgen, Paulsen, R. & Hempel, C., 2020, In: Infection and Immunity. 88, 3, e00679-19.Research output: Contribution to journal › Journal article › Research › peer-review
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VAR2CSA expression on the surface of placenta-derived Plasmodium falciparum-infected erythrocytes
Magistrado, P., Salanti, Ali, Tuikue Ndam, N. G., Mwakalinga, S. B., Resende, M., Dahlbäck, M., Hviid, Lars, Lusingu, J., Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2008, In: Journal of Infectious Diseases.Research output: Contribution to journal › Journal article › Research › peer-review
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CD36 selection of 3D7 Plasmodium falciparum associated with severe childhood malaria results in reduced VAR4 expression
Magistrado, P., Staalsoe, T., Theander, Thor Grundtvig, Hviid, Lars & Jensen, Anja Ramstedt, 2008, In: Malaria Journal. 7, 1, p. 204Research output: Contribution to journal › Journal article › Research › peer-review
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Immunoglobulin G antibody reactivity to a group A Plasmodium falciparum erythrocyte membrane protein 1 and protection from P. falciparum malaria
Magistrado, P. A., Lusingu, J., Vestergaard, L. S., Lemnge, M., Lavstsen, Thomas, Turner, Louise, Hviid, Lars, Jensen, Anja Ramstedt & Theander, Thor Grundtvig, 2007, In: Infection and Immunity. 75, 5, p. 2415-20 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High efficacy of anti DBL4e-VAR2CSA antibodies in inhibition of CSA-binding Plasmodium falciparum-infected erythrocytes from pregnant women
Magistrado, P. A., Minja, D., Doritchamou, J., Ndam, N. T., John, D., Schmiegelow, Christentze, Massougbodji, A., Dahlbäck, M., Ditlev, S. B., Pinto, V. V., Resende, M., Lusingu, J., Theander, Thor Grundtvig, Salanti, Ali & Nielsen, Morten Agertoug, 2011, In: Vaccine. 29, 3, p. 437-43 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The use of nominal group technique in identifying community health priorities in Moshi rural district, northern Tanzania
Makundi, E. A., Manongi, R., Mushi, A. K., Alilio, M. S., Theander, Thor Grundtvig, Rønn, A. M. & Bygbjerg, Ib Christian, 2005, In: Tanzania Health Research Bulletin. 7, 3, p. 133-41 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 11256
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Real-time and label free determination of ligand binding-kinetics to primary cancer tissue specimens; a novel tool for the assessment of biomarker targeting
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Bacterial superglue enables easy development of efficient virus-like particle based vaccines
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Placental sequestration of Plasmodium falciparum malaria parasites is mediated by the interaction between VAR2CSA and chondroitin sulfate A on syndecan-1
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