Ole Haagen Nielsen

Ole Haagen Nielsen

Clinical Professor

Member of:

  • Internal Medicine: Gastroenterology and Hepatology


  1. 2021
  2. Published

    Biologics During Pregnancy in Women With Inflammatory Bowel Disease and Risk of Infantile Infections: A Systematic Review and Meta-Analysis

    Gubatan, J. M., Nielsen, Ole Haagen, Levitte, S., Juhl, C. B., Maxwell, C., Streett, S. E. & Habtezion, A., 2021, In: Am J Gastroenterol. 116, 2, p. 243-253

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    IBD metabonomics predicts phenotype, disease course, and treatment response

    Bjerrum, Jakob Tveiten , Wang, Y. L., Seidelin, Jakob Benedict & Nielsen, Ole Haagen, 2021, In: EBioMedicine. 71, 103551.

    Research output: Contribution to journalReviewResearchpeer-review

  4. Published

    Telomere dysfunction instigates inflammation in inflammatory bowel disease

    Chakravarti, D., Lee, R., Multani, A. S., Santoni, A., Keith, Z., Hsu, W. H., Chang, K., Reyes, L., Rashid, A., Wu, C. J., Li, J., Zhang, J., Shim, H. S., Chandra, K., Deng, P., Spring, D. J., Nielsen, O. H., Riis, L. B., Mayigegowda, K. K., Blutt, S. E. & 9 others, Zhang, J., Younes, M., DuPont, A., Thirumurthi, S., Vilar, E., Estes, M. K., Colla, S., Shroyer, N. F. & DePinho, R. A., 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 29, e2024853118.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2020
  6. Published

    Efficacy and safety of methotrexate in the management of inflammatory bowel disease: A systematic review and meta-analysis of randomized, controlled trials

    Nielsen, Ole Haagen, Steenholdt, C., Juhl, C. B. & Rogler, G., Mar 2020, In: EClinicalMedicine. 20, 10 p., 100271.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A fully defined 3D matrix for ex vivo expansion of human colonic organoids from biopsy tissue

    Bergenheim, F., Fregni, G., Buchanan, C. F., Riis, Lene Buhl, Heulot, M., Touati, J., Seidelin, Jakob Benedict, Rizzi, S. C. & Nielsen, Ole Haagen, 2020, In: Biomaterials. 262, 11 p., 120248.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Immune Profiling of Human Gut-Associated Lymphoid Tissue Identifies a Role for Isolated Lymphoid Follicles in Priming of Region-Specific Immunity

    Fenton, T. M., Jørgensen, P. B., Niss, K., Rubin, S. J. S., Mörbe, U. M., Riis, Lene Buhl, Da Silva, C., Plumb, A., Vandamme, J., Jakobsen, H. L., Brunak, Søren, Habtezion, A., Nielsen, Ole Haagen, Johansson-Lindbom, B. & Agace, W. W., 2020, In: Immunity. 52, 3, p. 557-570, e1-e6

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Mucosal vitamin D signaling in inflammatory bowel disease

    Kellermann, L., Jensen, Kim Bak, Bergenheim, F., Gubatan, J., Chou, N. D., Moss, A. & Nielsen, Ole Haagen, 2020, In: Autoimmunity Reviews. 19, 11, 102672.

    Research output: Contribution to journalReviewResearchpeer-review

  10. Published

    SMAC mimetics and RIPK inhibitors as therapeutics for chronic inflammatory diseases

    Jensen, S., Seidelin, Jakob Benedict, LaCasse, E. C. & Nielsen, Ole Haagen, 2020, In: Science Signaling. 13, 619, 18 p., eaax8295.

    Research output: Contribution to journalReviewResearchpeer-review

  11. Published

    Telomere dysfunction activates YAP1 to drive tissue inflammation

    Chakravarti, D., Hu, B., Mao, X., Rashid, A., Li, J., Li, J., Liao, W. T., Whitley, E. M., Dey, P., Hou, P., LaBella, K. A., Chang, A., Wang, G., Spring, D. J., Deng, P., Zhao, D., Liang, X., Lan, Z., Lin, Y., Sarkar, S. & 16 others, Terranova, C., Deribe, Y. L., Blutt, S. E., Okhuysen, P., Zhang, J., Vilar, E., Nielsen, Ole Haagen, Dupont, A., Younes, M., Patel, K. R., Shroyer, N. F., Rai, K., Estes, M. K., Wang, Y. A., Bertuch, A. A. & DePinho, R. A., 2020, In: Nature Communications. 11, 13 p., 4766.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2019
  13. Published

    Metabonomics in gastroenterology and hepatology

    Bjerrum, Jakob Tveiten & Nielsen, Ole Haagen, 1 Aug 2019, In: International Journal of Molecular Sciences. 20, 15, 3638.

    Research output: Contribution to journalEditorialResearchpeer-review

  14. Published

    Biosimilars for management of Crohn disease

    Nielsen, Ole Haagen & Ainsworth, M. A., 2019, In: Annals of Internal Medicine. 170, 2, p. 129-130 2 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  15. Published

    Fluorescence-based tracing of transplanted intestinal epithelial cells using confocal laser endomicroscopy

    Bergenheim, F., Seidelin, Jakob Benedict, Pedersen, M. T., Mead, B. E., Jensen, Kim Bak, Karp, J. M. & Nielsen, Ole Haagen, 2019, In: Stem Cell Research & Therapy. 10, 1, p. 1-12 12 p., 148.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Managing vitamin D deficiency in inflammatory bowel disease

    Nielsen, Ole Haagen, Hansen, T. I., Gubatan, J. M., Jensen, Kim Bak & Rejnmark, L., 2019, In: Frontline Gastroenterology. 10, 4, p. 394-400 7 p., 31656565.

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    Methotrexate for inflammatory bowel disease: time for reconsideration

    Nielsen, Ole Haagen, Ainsworth, M. A. & Steenholdt, Casper, 2019, In: Expert Review of Gastroenterology and Hepatology. 13, 5, p. 407-409 3 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  18. Published

    Systematic review with meta-analysis: association of vitamin D status with clinical outcomes in adult patients with inflammatory bowel disease

    Gubatan, J., Chou, N. D., Nielsen, Ole Haagen & Moss, A. C., 2019, In: Alimentary Pharmacology and Therapeutics. 50, 11-12, p. 1146-1158 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  19. 2018
  20. Published

    Intestinal barrier integrity and inflammatory bowel disease: Stem cell-based approaches to regenerate the barrier

    Holmberg, F. E. O., Pedersen, J., Jørgensen, P., Soendergaard, C., Jensen, Kim Bak & Nielsen, Ole Haagen, Apr 2018, In: Journal of Tissue Engineering and Regenerative Medicine. 12, 4

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration

    Yui, S., Azzolin, L., Maimets, Martti, Pedersen, M. T., Fordham, R. P., Hansen, Stine Lind, Larsen, Hjalte List, Guiu, J., Alves, M. R. P., Friis, Carsten, Johansen, Jens Vilstrup, Li, Yuan, Madsen, C. D., Nakamura, T., Watanabe, M., Nielsen, Ole Haagen, Schweiger, P. J., Piccolo, S. & Jensen, Kim Bak, 1 Jan 2018, In: Cell Stem Cell. 22, 1, p. 35-49. e7 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    COX-2-PGE2 Signaling Impairs Intestinal Epithelial Regeneration and Associates with TNF Inhibitor Responsiveness in Ulcerative Colitis

    Li, Yuan, Soendergaard, C., Bergenheim, F. H., Aronoff, D. M., Milne, G., Riis, Lene Buhl, Seidelin, Jakob Benedict, Jensen, Kim Bak & Nielsen, Ole Haagen, 2018, In: EBioMedicine. 36, p. 497-507

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies

    Boyd, M., Thodberg, M., Vitezic, M., Lange, J. B., Vitting-Seerup, K., Chen, Y., Coskun, M., Li, Y., Lo, B. Z. S., Klausen, P., Schweiger, P., Pedersen, A. G., Rapin, N. P. J-P., Skovgaard, K., Dahlgaard, K., Andersson, R., Terkelsen, T. B., Lilje, B., Troelsen, J. T., Petersen, A. M. & 7 others, Jensen, Kim Bak, Gögenur, Ismail, Thielsen, P., Seidelin, Jakob Benedict, Nielsen, Ole Haagen, Bjerrum, Jakob Tveiten & Sandelin, Albin Gustav, 2018, In: Nature Communications. 9, 19 p., 1661.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Impact of red and processed meat and fibre intake on treatment outcomes among patients with chronic inflammatory diseases: protocol for a prospective cohort study of prognostic factors and personalised medicine

    Christensen, R., Heitmann, B. L., Andersen, K. W., Nielsen, O. H., Sørensen, S. B., Jawhara, M., Bygum, A., Hvid, L., Grauslund, J., Wied, J., Glerup, H., Fredberg, U., Villadsen, J. A., Kjær, S. G., Fallingborg, J., Moghadd, S. A. G. R., Knudsen, T., Brodersen, J., Frøjk, J., Dahlerup, J. F. & 21 others, Bojesen, A. B., Sørensen, G. L., Thiel, S., Færgeman, N. J., Brandslund, I., Bennike, T. B., Stensballe, A., Schmidt, E. B., Franke, A., Ellinghaus, D., Rosenstiel, P., Raes, J., Boye, M., Werner, L., Nielsen, C. L., Munk, H. L., Nexoe, A. B., Ellingsen, T., Holmskov, U., Kjeldsen, J. & Andersen, V., 2018, In: BMJ Open. 8, 2, 15 p., :e018166.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Inflammatory bowel disease with primary sclerosing cholangitis: A Danish population-based cohort study 1977-2011

    Sørensen, J. Ø., Nielsen, Ole Haagen, Andersson, M., Ainsworth, M. A., Ytting, H., Bélard, E. & Jess, T., 2018, In: Liver International. 38, 3, p. 532-541

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Putative biomarkers of vedolizumab resistance and underlying inflammatory pathways involved in IBD

    Soendergaard, C., Seidelin, Jakob Benedict, Steenholdt, C. & Nielsen, Ole Haagen, 2018, In: B M J Open Gastroenterology. 5, 1, e000208.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Rational Management of Iron-Deficiency Anaemia in Inflammatory Bowel Disease

    Nielsen, Ole Haagen, Soendergaard, C., Vikner, M. E. & Weiss, G., 2018, In: Nutrients. 10, 1, 25 p., 82.

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    Role of Vitamin D in the Natural History of Inflammatory Bowel Disease

    Nielsen, Ole Haagen, Rejnmark, L. & Moss, A. C., 2018, In: Journal of Crohn's and Colitis. 12, 6, p. 742-752 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  29. Published

    Targeting JAK-STAT signal transduction in IBD

    Soendergaard, C., Bergenheim, F. H., Bjerrum, Jakob Tveiten & Nielsen, Ole Haagen, 2018, In: Pharmacology & Therapeutics. 192, p. 100-111

    Research output: Contribution to journalJournal articleResearchpeer-review

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