Leila Lo Leggio

Leila Lo Leggio

Professor


  1. 2024
  2. Published

    A frontier-orbital view of the initial steps of lytic polysaccharide monooxygenase reactions

    Wieduwilt, E. K., Lo Leggio, Leila & Hedegård, E. D., 2024, In: Dalton Transactions (Online). 53, 13, p. 5796-5807 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    CI:Mor interactions in the lysogeny switches of Lactococcus lactis TP901-1 and Staphylococcus aureus φ13 bacteriophages

    Varming, A. K., Huang, Zhiyu, Hamad, G. M., Rasmussen, K. K., Ingmer, Hanne, Kilstrup, M. & Lo Leggio, Leila, 2024, In: Microbiome Research Reports. 3, 2, 16 p., 15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Chemoenzymatic indican for light-driven denim dyeing

    Bidart, G. N., Teze, D., Jansen, C. U., Pasutto, E., Putkaradze, N., Sesay, A. M., Fredslund, F., Lo Leggio, Leila, Ögmundarson, O., Sukumara, S., Qvortrup, K. & Welner, D. H., 2024, In: Nature Communications. 15, 1, 11 p., 1489.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Polysaccharide utilization loci from Bacteroidota encode CE15 enzymes with possible roles in cleaving pectin-lignin bonds

    Seveso, A., Mazurkewich, S., Banerjee, S., Poulsen, Jens-Christian Navarro, Lo Leggio, Leila & Larsbrink, J., 2024, In: Applied and Environmental Microbiology. 90, 1, 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2023
  7. Published

    AA16 Oxidoreductases Boost Cellulose-Active AA9 Lytic Polysaccharide Monooxygenases from Myceliophthora thermophila

    Sun, P., Huang, Zhiyu, Banerjee, S., Kadowaki, M. A. S., Veersma, R. J., Magri, S., Hilgers, R., Muderspach, Sebastian Jannick, Laurent, C. V. F. P., Ludwig, R., Cannella, D., Lo Leggio, Leila, van Berkel, W. J. H. & Kabel, M. A., 2023, In: ACS Catalysis. 13, 7, p. 4454-4467 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Glucuronoyl esterases – enzymes to decouple lignin and carbohydrates and enable better utilization of renewable plant biomass

    Larsbrink, J. & Lo Leggio, Leila, 2023, In: Essays in Biochemistry. 67, 3, p. 493-503 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  9. Published

    Joint X-ray/neutron structure of Lentinus similis AA9_A at room temperature

    Tandrup, T., Lo Leggio, Leila & Meilleur, F., 2023, In: Acta crystallographica. Section F, Structural biology communications. 79, 1, p. 1-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Structural and functional investigation of a fungal member of carbohydrate esterase family 15 with potential specificity for rare xylans

    Mazurkewich, S., Scholzen, K. C., Brusch, R. H., Poulsen, Jens-Christian Navarro, Theibich, Yusuf, Hüttner, S., Olsson, L., Larsbrink, J. & Lo Leggio, Leila, 2023, In: Acta crystallographica. Section D, Structural biology. 79, 6, p. 545-555 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Structure, function, and protein engineering of GH53 β-1,4-galactanases

    Muderspach, Sebastian Jannick, Jensen, K., Krogh, K. B. R. M. & Lo Leggio, Leila, 2023, Glycoside Hydrolases: Biochemistry, Biophysics, and Biotechnology. Elsevier, p. 295-322 28 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  12. 2022
  13. Published

    Mechanism and biomass association of glucuronoyl esterase: an α/β hydrolase with potential in biomass conversion

    Zong, Z., Mazurkewich, S., Pereira, C. S., Fu, H., Cai, W., Shao, X., Skaf, M. S., Larsbrink, J. & Lo Leggio, Leila, Dec 2022, In: Nature Communications. 13, 1, 10 p., 1449.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Changes in active-site geometry on X-ray photo-reduction of a lytic polysaccharide monooxygenase active-site copper and saccharide binding

    Tandrup, T., Muderspach, Sebastian Jannick, Banerjee, S., Santoni, G., Ipsen, J. O., Hernandez Rollan, Cristina, Norholm, M. H. H., Johansen, Katja Salomon, Meilleur, F. & Lo Leggio, Leila, Sep 2022, In: IUCrJ. 9, 5, p. 666-681 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Flexible linker modulates the binding affinity of the TP901-1 CI phage repressor to DNA

    Varming, A. K., Rasmussen, K. K., Zong, Z., Thulstrup, Peter Waaben, Kilstrup, M. & Lo Leggio, Leila, 2022, In: FEBS Journal. 289, 4, p. 1135-1148 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Protonation State of an Important Histidine from High Resolution Structures of Lytic Polysaccharide Monooxygenases

    Banerjee, S., Muderspach, Sebastian Jannick, Tandrup, T., Frandsen, Kristian Erik Høpfner, Singh, R. K., Ipsen, J. O., Hernandez Rollan, Cristina, Nørholm, M. H. H., Bjerrum, Morten Jannik, Johansen, Katja Salomon & Lo Leggio, Leila, 2022, In: Biomolecules. 12, 2, 15 p., 194.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2021
  18. Published

    Engineering the substrate binding site of the hyperthermostable archaeal endo-β-1,4-galactanase from Ignisphaera aggregans

    Muderspach, Sebastian Jannick, Fredslund, F., Volf, V., Poulsen, Jens-Christian Navarro, Blicher, T. H., Clausen, M. H., Rasmussen, K. K., Krogh, K. B. R. M., Jensen, K. & Lo Leggio, Leila, 1 Dec 2021, In: Biotechnology for Biofuels. 14, 1, 16 p., 183.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Characterization of the genetic switch from phage ɸ13 important for Staphylococcus aureus colonization in humans

    Kristensen, C. S., Varming, A. K., Leinweber, H. A. K., Hammer, K., Lo Leggio, Leila, Ingmer, Hanne & Kilstrup, M., 1 Oct 2021, In: MicrobiologyOpen. 10, 5, 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Structural and Functional Analysis of a Multimodular Hyperthermostable Xylanase-Glucuronoyl Esterase from Caldicellulosiruptor kristjansonii

    Krska, D., Mazurkewich, S., Brown, H. A., Theibich, Yusuf, Poulsen, Jens-Christian Navarro, Morris, A. L., Koropatkin, N. M., Lo Leggio, Leila & Larsbrink, J., 13 Jul 2021, In: Biochemistry. 60, 27, p. 2206-2220 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Crystal structures of Val58Ile tryptophan repressor in a domain-swapped array in the presence and absence of L-tryptophan

    Sprenger, J., Lawson, C. L., Von Wachenfeldt, C., Lo Leggio, Leila & Carey, J., 1 Jul 2021, In: Acta Crystallographica Section F: Structural Biology Communications. 77, 7, p. 215-225 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Probing the determinants of the transglycosylation/hydrolysis partition in a retaining α-L-arabinofuranosidase

    Zhao, J., Tandrup, T., Bissaro, B., Barbe, S., Poulsen, Jens-Christian Navarro, André, I., Dumon, C., Lo Leggio, Leila, O'Donohue, M. J. & Fauré, R., 25 May 2021, In: New Biotechnology. 62, p. 68-78 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Estimating the accuracy of calculated electronparamagnetic resonance hyperfine couplings for alytic polysaccharide monooxygenase

    Theibich, Y. A., Sauer, Stephan P. A., Lo Leggio, Leila & Hedegård, E. D., 12 Jan 2021, In: Computational and Structural Biotechnology Journal. 19, p. 555-567 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Identification of the molecular determinants driving the substrate specificity of fungal lytic polysaccharide monooxygenases (LPMOs)

    Frandsen, Kristian Erik Høpfner, Haon, M., Grisel, S., Henrissat, B., Lo Leggio, Leila & Berrin, J., 1 Jan 2021, In: Journal of Biological Chemistry. 296, 11 p., 100086.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Calmodulin complexes with brain and muscle creatine kinase peptides

    Sprenger, J., Trifan, A., Patel, N., Vanderbeck, A., Bredfelt, J., Tajkhorshid, E., Rowlett, R., Lo Leggio, Leila, Åkerfeldt, K. S. & Linse, S., 2021, In: Current Research in Structural Biology. 3, p. 121-132 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Controlling the fractal dimension in self-assembly of terpyridine modified insulin by Fe2+ and Eu3+ to direct in vivo effects

    Mishra, N. K., Østergaard, M., Midtgaard, S. R., Strindberg, S. S., Winkler, S., Wu, S., Sørensen, Thomas Just, Hassenkam, Tue, Poulsen, Jens-Christian Navarro, Lo Leggio, Leila, Nielsen, Hanne Mørck, Arleth, Lise, Christensen, Niels Johan, Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2021, In: Nanoscale. 13, 18, p. 8467–8473 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Copper binding and reactivity at the histidine brace motif: insights from mutational analysis of the Pseudomonas fluorescens copper chaperone CopC

    Ipsen, J. Ø., Hernández‐Rollán, C., Muderspach, Sebastian Jannick, Brander, Søren, Bertelsen, A. B., Jensen, Poul Erik, Nørholm, M. H. H., Lo Leggio, Leila, Johansen, Katja Salomon & Ferguson, S. (ed.), 2021, In: FEBS Letters. 595, 12, p. 1708-1720 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Guest-protein incorporation into solvent channels of a protein host crystal (hostal)

    Sprenger, J., Carey, J., Schulz, Alexander, Drouard, F., Lawson, C. L., Von Wachenfeldt, C., Linse, S. & Lo Leggio, Leila, 2021, In: Acta crystallographica Section D: Structural biology . 77, p. 471-485 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Inhibition of lytic polysaccharide monooxygenase by natural plant extracts

    Tokin, Radina, Frandsen, Kristian Erik Høpfner, Ipsen, J. Ø., Lo Leggio, Leila, Poojary, Mahesha Manjunatha, Berrin, J., Grisel, S., Brander, Søren, Jensen, Poul Erik & Johansen, Katja Salomon, 2021, In: New Phytologist. 232, 3, p. 1337–1349 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Lytic polysaccharide monooxygenases and other histidine-brace copper proteins: structure, oxygen activation and biotechnological applications

    Ipsen, J., Hallas-Møller, Magnus, Brander, Søren, Lo Leggio, Leila & Johansen, Katja Salomon, 2021, In: Biochemical Society Transactions. 49, 1, p. 531-540 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  31. Published

    Scission of Glucosidic Bonds by a Lentinus similis Lytic Polysaccharide Monooxygenases Is Strictly Dependent on H2O2while the Oxidation of Saccharide Products Depends on O2

    Brander, Søren, Tokin, Radina, Ipsen, J., Jensen, Poul Erik, Hernández-Rollán, C., Nørholm, M. H. H., Lo Leggio, Leila, Dupree, P. & Johansen, Katja Salomon, 2021, In: ACS Catalysis. 11, 22, p. 13848-13859

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2020
  33. Published

    Biochemical evidence of both copper chelation and oxygenase activity at the histidine brace

    Brander, Søren, Horvath, I., Ipsen, J. Ø., Peciulyte, A., Olsson, L., Hernández-rollán, C., Nørholm, M. H. H., Mossin, S., Lo Leggio, Leila, Probst, C., Thiele, D. J. & Johansen, Katja Salomon, 1 Dec 2020, In: Scientific Reports. 10, 1, 11 p., 16369.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Revealing the mechanism of repressor inactivation during switching of a temperate bacteriophage

    Rasmussen, K. K., Palencia, A., Varming, A. K., El-Wali, H., Erba, E. B., Blackledge, M., Hammer, K., Herrmann, T., Kilstrup, M., Lo Leggio, Leila & Jensen, M. R., 25 Aug 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 34, p. 20576-20585 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Repression of the lysogenic PR promoter in bacteriophage TP901-1 through binding of a CI-MOR complex to a composite OM-OR operator

    Pedersen, M., Neergaard, J. T., Cassias, J., Rasmussen, K. K., Lo Leggio, Leila, Sneppen, Kim, Hammer, K. & Kilstrup, M., 26 May 2020, In: Scientific Reports. 10, 1, 13 p., 8659.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    An 1,4-α-Glucosyltransferase Defines a New Maltodextrin Catabolism Scheme in Lactobacillus acidophilus

    Andersen, S., Møller, M. S., Poulsen, Jens-Christian Navarro, Pichler, M. J., Svensson, B., Lo Leggio, Leila, Goh, Y. J. & Abou Hachem, M., 22 May 2020, In: Applied and Environmental Microbiology. 86, 15, 14 p., e00661-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    A fungal family of lytic polysaccharide monooxygenase-like copper proteins

    Labourel, A., Frandsen, Kristian Erik Høpfner, Zhang, F., Brouilly, N., Grisel, S., Haon, M., Ciano, L., Ropartz, D., Fanuel, M., Martin, F., Navarro, D., Rosso, M., Tandrup, T., Bissaro, B., Johansen, Katja Salomon, Zerva, A., Walton, P. H., Henrissat, B., Lo Leggio, Leila & Berrin, J., 2020, In: Nature Chemical Biology. 16, p. 345-350 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    A lytic polysaccharide monooxygenase-like protein functions in fungal copper import and meningitis

    Garcia-Santamarina, S., Probst, C., Festa, R. A., Ding, C., Smith, A. D., Conklin, S. E., Brander, Søren, Kinch, L. N., Grishin, N. V., Franz, K. J., Riggs-Gelasco, P., Lo Leggio, Leila, Johansen, Katja Salomon & Thiele, D. J., 2020, In: Nature Chemical Biology. 16, p. 337-344 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Oligosaccharide Binding and Thermostability of Two Related AA9 Lytic Polysaccharide Monooxygenases

    Tandrup, T., Tryfona, T., Frandsen, Kristian Erik Høpfner, Johansen, Katja Salomon, Dupree, P. & Lo Leggio, Leila, 2020, In: Biochemistry. 59, 36, p. 3347-3358 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. 2019
  41. Published

    Structural studies of temperate phage genetic switches

    Varming, A., Rasmussen, K. K., Kilstrup, M., Hammer, K., Ringkjøbing Jensen, M., Ingmer, Hanne & Lo Leggio, Leila, 18 Aug 2019, p. e105-e105. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  42. Published

    Evolutionary adaptation in fucosyllactose uptake systems supports bifidobacteria-infant symbiosis

    Sakanaka, M., Hansen, M. E., Gotoh, A., Katoh, T., Yoshida, K., Odamaki, T., Yachi, H., Sugiyama, Y., Kurihara, S., Hirose, J., Urashima, T., Xiao, J., Kitaoka, M., Fukiya, S., Yokota, A., Lo Leggio, Leila, Abou Hachem, M. & Katayama, T., 2019, In: Science Advances. 5, 8, p. 1-15 15 p., eaaw7696.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Further structural studies of the lytic polysaccharide monooxygenase AoAA13 belonging to the starch-active AA13 family

    Muderspach, Sebastian Jannick, Tandrup, T., Frandsen, Kristian Erik Høpfner, Santoni, G., Poulsen, Jens-Christian Navarro & Lo Leggio, Leila, 2019, In: Amylase. 3, 1, p. 41-54 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Insights into an unusual Auxiliary Activity 9 family member lacking the histidine brace motif of lytic polysaccharide monooxygenases

    Frandsen, Kristian Erik Høpfner, Tovborg, M., Jørgensen, C. I., Spodsberg, N., Rosso, M., Hemsworth, G. R., Garman, E. F., Grime, G. W., Poulsen, Jens-Christian Navarro, Batth, T. S., Miyauchi, S., Lipzen, A., Daum, C., Grigoriev, I. V., Johansen, Katja Salomon, Henrissat, B., Berrin, J. & Lo Leggio, Leila, 2019, In: The Journal of Biological Chemistry. 294, p. 17117-17130 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Structural and biochemical studies of the glucuronoyl esterase OtCE15A illuminate its interaction with lignocellulosic components

    Mazurkewich, S., Poulsen, Jens-Christian Navarro, Lo Leggio, Leila & Larsbrink, J., 2019, In: Journal of Biological Chemistry. 294, 52, p. 19978-19987

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Structure and Dynamics of a Promiscuous Xanthan Lyase from Paenibacillus nanensis and the Design of Variants with Increased Stability and Activity

    Jensen, P. F., Kadziola, Anders, Comamala, G., Segura, D. R., Anderson, L., Poulsen, Jens-Christian Navarro, Rasmussen, K. K., Agarwal, S., Sainathan, R. K., Monrad, R. N., Svendsen, A., Nielsen, J. E., Lo Leggio, Leila & Rand, Kasper Dyrberg, 2019, In: Cell Chemical Biology. 26, 2, p. 191-202.e1-e6 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Structure of Aspergillus aculeatus β-1,4-galactanase in complex with galactobiose

    Torpenholt, S., Poulsen, Jens-Christian Navarro, Muderspach, Sebastian Jannick, De Maria, L. & Lo Leggio, Leila, 2019, In: Acta Crystallographica Section F: Structural Biology Communications. 75, 6, p. 399-404 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Structure–function analyses reveal that a glucuronoyl esterase from Teredinibacter turnerae interacts with carbohydrates and aromatic compounds

    Arnling Bååth, J., Mazurkewich, S., Poulsen, Jens-Christian Navarro, Olsson, L., Lo Leggio, Leila & Larsbrink, J., 2019, In: Journal of Biological Chemistry. 294, 16, p. 6635-6644 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Substrate preference of an ABC importer corresponds to selective growth on β-(1,6)-galactosides in Bifidobacterium animalis subsp. lactis

    Theilmann, M. C., Fredslund, F., Svensson, B., Lo Leggio, Leila & Abou Hachem, M., 2019, In: Journal of Biological Chemistry. 294, 31, p. 11701-11711 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. 2018
  51. Published

    Biochemical and structural features of diverse bacterial glucuronoyl esterases facilitating recalcitrant biomass conversion

    Baath, J. A., Mazurkewich, S., Knudsen, R. M., Poulsen, Jens-Christian Navarro, Olsson, L., Lo Leggio, Leila & Larsbrink, J., 2018, In: Biotechnology for Biofuels. 11, 14 p., 213.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    NCAM2 Fibronectin type-III domains form a rigid structure that binds and activates the Fibroblast Growth Factor Receptor

    Rasmussen, K. K., Falkesgaard, M. H., Winther, M., Roed, N. K., Quistgaard, C. L. A., Teisen, M. N., Edslev, S. M., Petersen, D. L., Aljubouri, A., Christensen, C., Thulstrup, Peter Waaben, Lo Leggio, Leila, Teilum, Kaare & Walmod, P. S., 2018, In: Scientific Reports. 8, 13 p., 8957 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Recent insights into lytic polysaccharide monooxygenases (LPMOs)

    Tandrup, T., Frandsen, Kristian Erik Høpfner, Johansen, Katja Salomon, Berrin, J. & Lo Leggio, Leila, 2018, In: Biochemical Society Transactions. 46, 6, p. 1431-1447 17 p.

    Research output: Contribution to journalReviewResearchpeer-review

  54. Published

    Structural basis of the bacteriophage TP901‐1 CI repressor dimerization and interaction with DNA

    Rasmussen, K. K., Varming, A. K., Schmidt, S. N., Frandsen, Kristian Erik Høpfner, Thulstrup, Peter Waaben, Jensen, M. R. & Lo Leggio, Leila, 2018, In: F E B S Letters. 592, 10, p. 1738-1750 13 p.

    Research output: Contribution to journalLetterResearchpeer-review

  55. Published

    Structure of a hyperthermostable carbonic anhydrase identified from an active hydrothermal vent chimney

    Fredslund, F., Borchert, M. S., Poulsen, Jens-Christian Navarro, Mortensen, S. B., Perner, M., Streit, W. R. & Lo Leggio, Leila, 2018, In: Enzyme and Microbial Technology. 114, p. 48-54 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Structure of a lytic polysaccharide monooxygenase from Aspergillus fumigatus and an engineered thermostable variant

    Lo Leggio, Leila, Weihe, C. D., Poulsen, Jens-Christian Navarro, Sweeney, M., Rasmussen, F., Lin, J., De Maria, L. & Wogulis, M., 2018, In: Carbohydrate Research. 469, p. 55-59 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016)

    Kryshtafovych, A., Albrecht, R., Basle, A., Bule, P., Caputo, A. T., Carvalho, A. L., Chao, K. L., Diskin, R., Fidelis, K., Fontes, C. M. G. A., Fredslund, F., Gilbert, H. J., Goulding, C. W., Hartmann, M. D., Hayes, C. S., Herzberg, O., Hill, J. C., Joachimiak, A., Kohring, G-W., Koning, R. I. & 19 others, Lo Leggio, Leila, Mangiagalli, M., Michalska, K., Moult, J., Najmudin, S., Nardini, M., Nardone, V., Ndeh, D., Nguyen, T., Pintacuda, G., Postel, S., van Raaij, M. J., Roversi, P., Shimon, A., Singh, A. K., Sundberg, E. J., Tars, K., Zitzmann, N. & Schwede, T., 2018, In: Proteins: Structure, Function, and Bioinformatics. 86, S1, p. 27-50 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. 2017
  59. Published

    Discovery of α-L-arabinopyranosidases from human gut microbiome expands the diversity within glycoside hydrolase family 42

    Viborg, A. H., Katayama, T., Arakawa, T., Abou Hachem, M., Lo Leggio, Leila, Kitaoka, M., Svensson, B. & Fushinobu, S., 2017, In: Journal of Biological Chemistry. 292, 51, p. 21092-21101 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Expression, refolding and spectroscopic characterization of fibronectin type III (FnIII)-homology domains derived from human fibronectin leucine rich transmembrane protein (FLRT)-1,-2, and-3

    Yang, L., Falkesgaard, M. H., Thulstrup, Peter Waaben, Walmod, P. S., Lo Leggio, Leila & Rasmussen, K. K., 2017, In: PeerJ. 5, 16 p., e3550.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Learning from oligosaccharide soaks of crystals of an AA13 lytic polysaccharide monooxygenase: crystal packing, ligand binding and active-site disorder

    Frandsen, Kristian Erik Høpfner, Poulsen, Jens-Christian Navarro, Tovborg, M., Johansen, Katja Salomon & Lo Leggio, Leila, 2017, In: Acta crystallographica Section D: Structural biology . 73, p. 64-76 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Structural and electronic determinants of lytic polysaccharide monooxygenase reactivity on polysaccharide substrates

    Simmons, T. J., Frandsen, Kristian Erik Høpfner, Ciano, L., Tryfona, T., Lenfant, N., Poulsen, Jens-Christian Navarro, Wilson, L. F. L., Tandrup, T., Tovborg, M., Schnorr, K., Johansen, Katja Salomon, Henrissat, B., Walton, P. H., Lo Leggio, Leila & Dupree, P., 2017, In: Nature Communications. 8, 12 p., 1064.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Unliganded and substrate bound structures of the cellooligosaccharide active lytic polysaccharide monooxygenase LsAA9A at low pH

    Frandsen, Kristian Erik Høpfner, Poulsen, Jens-Christian Navarro, Tandrup, T. & Lo Leggio, Leila, 2017, In: Carbohydrate Research. 448, p. 187-190 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. 2016
  65. Published

    Enzymatisk nedbrydning af polysaccharider

    Lo Leggio, Leila, Tovborg, M. & Johansen, K. S., 2016, In: Dansk Kemi. 97, 4, p. 23-25 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Lytic polysaccharide monooxygenases: a crystallographer's view on a new class of biomass-degrading enzymes

    Frandsen, Kristian Erik Høpfner & Lo Leggio, Leila, 2016, In: IUCrJ. 3, Part 6, p. 448-467 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    NAC transcription factors: from structure to function in stress-associated networks

    Welner, D. H., Deeba, F., Lo Leggio, Leila & Skriver, Karen, 2016, Plant transcription factors: evolutionary, structural and functional aspects. Gonzalez, D. H. (ed.). Academic Press, p. 199-212 14 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  68. Published

    Structural and dynamics studies of a truncated variant of CI repressor from bacteriophage TP901-1

    Rasmussen, K. K., Frandsen, Kristian Erik Høpfner, Boeri Erba, E., Pedersen, M., Varming, A. K., Hammer, K., Kilstrup, M., Thulstrup, Peter Waaben, Blackledge, M., Jensen, M. R. & Lo Leggio, Leila, 2016, In: Scientific Reports. 6, 12 p., 29574.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Structural characterization of the thermostable Bradyrhizobium japonicum D-sorbitol dehydrogenase

    Fredslund, F., Otten, H., Gemperlein, S., Poulsen, Jens-Christian Navarro, Carius, Y., Kohring, G. & Lo Leggio, Leila, 2016, In: Acta Crystallographica Section F. 72, 11, p. 846-852 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    The molecular basis of polysaccharide cleavage by lytic polysaccharide monooxygenases

    Frandsen, K. E. H., Simmons, T. J., Dupree, P., Poulsen, J-C. N., Hemsworth, G. R., Ciano, L., Johnston, E. M., Tovborg, M., Johansen, K. S., von Freiesleben, P., Marmuse, L., Fort, S., Cottaz, S., Driguez, H., Henrissat, B., Lenfant, N., Tuna, F., Baldansuren, A., Davies, G. J., Lo Leggio, L. & 1 others, Walton, P. H., 2016, In: Nature Chemical Biology. 12, 4, p. 298-303 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. 2015
  72. Published

    Effect of mutations on the thermostability of Aspergillus aculeatus β-1,4-galactanase

    Torpenholt, S. K., De Maria, L., Olsson, M. H. M., Christensen, L. H., Skjøt, M., Westh, P., Jensen, Jan Halborg & Lo Leggio, Leila, 2015, In: Computational and Structural Biotechnology Journal. 13, p. 256-264 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Structural diversity of lytic polysaccharide monooxygenases

    Lo Leggio, Leila, Frandsen, Kristian Erik Høpfner, Poulsen, Jens-Christian Navarro, Tovborg, M., De Maria, L. & Johansen, K. S., 2015, Proceedings of "Mie Bioforum 2014 - Lignocellulose Degradation and Biorefinery". Sakka, K., Kimura, T., Tamaru, Y., Karita, S. & Sakka, M. (eds.). UNI Publishers Co., Ltd, p. 148-156 9 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  74. Published

    Structure and boosting activity of a starch-degrading lytic polysaccharide monooxygenase

    Lo Leggio, Leila, Simmons, T. J., Poulsen, Jens-Christian Navarro, Frandsen, Kristian Erik Høpfner, Hemsworth, G. R., Stringer, M. A., von Freiesleben, P., Tovborg, M., Johansen, Katja Salomon, De Maria, L., Harris, P. V., Soong, C., Dupree, P., Tryfona, T., Lenfant, N., Henrissat, B., Davies, G. J. & Walton, P. H., 2015, In: Nature Communications. 6, 9 p., 5961.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Structure of dimeric, recombinant Sulfolobus solfataricus phosphoribosyl diphosphate synthase: a bent dimer defining the adenine specificity of the substrate ATP

    Andersen, R. W., Lo Leggio, Leila, Hove-Jensen, B. & Kadziola, Anders, 2015, In: Extremophiles. 19, 2, p. 407-415 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. 2014
  77. Published

    A β1-6/β1-3 galactosidase from Bifidobacterium animalis subsp. lactis Bl-04 gives insight into sub-specificities of β-galactoside catabolism within Bifidobacterium

    Viborg, A. H., Fredslund, F., Katayama, T., Nielsen, S. K., Svensson, B., Kitaoka, M., Lo Leggio, Leila & Abou Hachem, M., 2014, In: Molecular Microbiology. 94, 5, p. 1024-1040 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    An L-glucitol oxidizing dehydrogenase from Bradyrhizobium japonicum USDA 110 for production of D-sorbose with enzymatic or electrochemical cofactor regeneration

    Gauer, S., Wang, Z., Otten, H., Etienne, M., Bjerrum, Morten Jannik, Lo Leggio, Leila, Walcarius, A., Giffhorn, F. & Kohring, G., 2014, In: Applied Microbiology and Biotechnology. 98, 7, p. 3023-3032 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Polysaccharide lyase family 4

    Lo Leggio, Leila & Larsen, Sine, 2014, Cazypedia.

    Research output: Chapter in Book/Report/Conference proceedingEncyclopedia chapterResearch

  80. Published

    Purification, crystal structure determination and functional characterization of type III antifreeze proteins from the European eelpout Zoarces viviparus

    Wilkens, C., Poulsen, Jens-Christian Navarro, Ramløv, H. & Lo Leggio, Leila, 2014, In: Cryobiology. 69, 1, p. 163-168 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. 2013
  82. Published

    A snapshot into the metabolism of isomalto-oligosaccharides in probiotic bacteria

    Abou Hachem, M., Møller, M. S., Andersen, J. M., Fredslund, F., Majumder, A., Nakai, H., Lo Leggio, Leila, Goh, Y., Barrangou, R., Klaenhammer, T. R. & Svensson, B., 2013, In: Journal of Applied Glycoscience. 60, 2, p. 95-100 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Binding of the N-terminal domain of the lactococcal bacteriophage TP901-1 CI repressor to its target DNA: a crystallography, small angle scattering, and nuclear magnetic resonance study

    Frandsen, Kristian Erik Høpfner, Rasmussen, K. K., Jensen, M. R., Hammer, K., Pedersen, M., Poulsen, Jens-Christian Navarro, Arleth, Lise & Lo Leggio, Leila, 2013, In: Biochemistry. 52, 39, p. 6892-6904 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Crystallization and preliminary crystallographic analysis of an Escherichia coli-selected mutant of the nuclease domain of the metallonuclease colicin E7

    Czene, A., Toth, E., Gyurcsik, B., Otten, H., Poulsen, Jens-Christian Navarro, Lo Leggio, Leila, Larsen, Sine, Christensen, H. E. M. & Nagata, K., 2013, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 69, p. 551-554 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Recent insight into oligosaccharide uptake and metabolism in probiotic bacteria

    Abou Hachem, M., Andersen, J. M., Barrangou, R., Møller, M. S., Fredslund, F., Majumder, A., Hansen, M. E., Lahtinen, S. J., Jacobsen, S., Lo Leggio, Leila, Goh, Y. J., Klaenhammer, T. R. & Svensson, B., 2013, In: Biocatalysis and Biotransformation. 31, 4, p. 226-235 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. 2012
  87. Published

    A structural overview of GH61proteins – fungal cellulose degrading polysaccharide monooxygenases

    Lo Leggio, Leila, Welner, D. H. & De Maria, L., 2012, In: Computational and Structural Biotechnology Journal. 2, 3, p. 1-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    DNA binding by the plant-specific NAC transcription factors in crystal and solution: a firm link to WRKY and GCM transcription factors

    Welner, D. H., Lindemose, Søren, Grossmann, J. G., Møllegaard, Niels Erik, Olsen, A. N., Helgstrand, C., Skriver, Karen & Lo Leggio, Leila, 2012, In: Biochemical Journal. 444, p. 395-404 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Enzymology and structure of the GH13_31 glucan 1,6-a-glucosidase that confers isomaltooligosaccharide utilization in the probiotic Lactobacillus acidophilus NCFM

    Møller, M. S., Fredslund, F., Majumder, A., Nakai, H., Poulsen, Jens-Christian Navarro, Lo Leggio, Leila, Svensson, B. & Abou Hachem, M., 2012, In: Journal of Bacteriology. 194, 16, p. 4249-4259 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Glycoside hydrolase family 53 - CAZYpedia entry

    Lo Leggio, Leila, 2012

    Research output: Other contributionNet publication - Internet publicationCommunication

  91. Published

    Raffinose family oligosaccharide utilisation by probiotic bacteria: insight into substrate recognition, molecular architecture and diversity of GH36 a-galactosidases

    Abou Hachem, M., Fredslund, F., Andersen, J. M., Larsen, R. J., Majumder, A., Hansen, M. E., van Zanten, G. C., Lahtinen, S. J., Barrangou, R., Klaenhammer, T., Jacobsen, S., Coutinho, P. M., Lo Leggio, Leila & Svensson, B., 2012, In: Biocatalysis and Biotransformation. 30, 3, p. 316-325 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Structure-based engineering of glucose specificity in a family 10 xylanase from Streptomyces olivaceoviridis E-86

    Ichinose, H., Diertavitian, S. W. S., Fujimoto, Z., Kuno, A., Lo Leggio, Leila & Kaneko, S., 2012, In: Process Biochemistry. 47, 3, p. 358-365 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. 2011
  94. Published

    Activity of three ß-1,4-galactanases on small chromogenic substrates

    Torpenholt, S. K., Le Nours, J., Christensen, U., Jahn, M., Withers, S., Østergaard, P., Borchert, T. V., Poulsen, Jens-Christian Navarro & Lo Leggio, Leila, 2011, In: Carbohydrate Research. 346, p. 2028-2033

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Crystal structure of a-galactosidase from Lactobacillus acidophilus NCFM: insight into tetramer formation and substrate binding

    Fredslund, F., Abou Hachem, M., Larsen, R. J., Sørensen, P. G., Pedro, C., Lo Leggio, Leila & Svensson, B., 2011, In: Journal of Molecular Biology. 412, 466-480, p. 466–480

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Insights into the oxidative degradation of cellulose by a copper metalloenzyme that exploits biomass components to cleave cellulose

    Quinlan, R. J., Sweeney, M. D., Lo Leggio, Leila, Otten, H., Poulsen, Jens-Christian Navarro, Johansen, K. S., Krogh, K. B. R. M., Jørgensen, C. I., Tovborg, M., Anthonsen, A., Tryfona, T., Tryfona, T., Walter, C. P., Dupree, P., Xu, F., Davies, G. J. & Walton, P. H., 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, p. 15079-15084

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Structure of a fungal dimeric a-type carbonic anhydrase

    Cuesta Seijo, J. A., Borchert, M. S., Poulsen, Jens-Christian Navarro, Schnorr, K. M., Mortensen, S. B. & Lo Leggio, Leila, 2011, In: F E B S Letters. 585, p. 1042-1048

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. 2010
  99. Published

    Rational engineering of mannosyl binding in the distal glycone subsites of Cellulomonas fimi endo-ß-1,4-mannanase: mannosyl binding promoted at subsite -2 and demoted at subsite -3

    Hekmat, O., Lo Leggio, Leila, Rosengren, A., Kamarauskaite, J., Kolenova, K. & Stålbrand, H., 2010, In: Biochemistry. 49

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Rational engineering of mannosyl binding in the distal glycone subsites of Cellulomonas fimi endo-β-1,4-mannanase: mannosyl binding promoted at subsite -2 and demoted at subsite -3

    Hekmat, O., Lo Leggio, Leila, Rosengren, A., Kamarauskaite, J., Kolenova, K. & Stålbrand, H., 2010, In: Biochemistry. 49, 23, p. 4884-4896 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Stimulation of lignocellulosic biomass hydrolysis by proteins of glycoside hydrolase family 61: Structure and function of a large, enigmatic family

    Harris, P. V., Welner, D. H., McFarland, K., Re, E., Poulsen, Jens-Christian Navarro, Brown, K., Salbo, R., Ding, H., Vlasenko, E., Marino, S., Xu, F., Cherry, J., Larsen, Sine & Lo Leggio, Leila, 2010, In: Biochemistry. 49, p. 3305-3316

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    Structural and biochemical studies elucidate the mechanism of rhamnogalacturonan lyase from Aspergillus aculeatus

    Jensen, M. H., Otten, H., Christensen, U., Borchert, T. V., Christensen, L. L. H., Larsen, Sine & Lo Leggio, Leila, 2010, In: Journal of Molecular Biology. 404, p. 100-111

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. 2009
  104. Published

    Crystal structure of A. acidocaldarius Endoglucanase Cel9A in complex with cello-oligosaccharides: strong -1 and -2 subsites mimic cellobiohydrolase activity

    Eckert, K., Vigouroux, A., Lo Leggio, Leila & Morera, S., 2009, In: Journal of Molecular Biology. 394, 1, p. 61-70

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. Published

    Investigating the binding of beta-1,4-galactan to Bacillus licheniformis beta-1,4-galactanase by crystallography and computational modeling

    Le Nours, J., De Maria, L., Welner, D. H., Jørgensen, C. T., Borchert, T. V., Christensen, L. L., Larsen, Sine & Lo Leggio, Leila, 2009, In: Proteins - Structure Function and Bioinformatics. 75, p. 977-989

    Research output: Contribution to journalJournal articleResearchpeer-review

  106. 2008
  107. Published

    Kinetics and stereochemistry of the Cellulomonas fimi β-mannanase studied using 1 H-NMR

    Anderson, L., Hägglund, Per Mårten, Stoll, D., Lo Leggio, Leila, Drakenberg, T. & Stålbrand, H., 1 Jan 2008, In: Biocatalysis and Biotransformation. 26, 1-2, p. 86-95

    Research output: Contribution to journalJournal articleResearchpeer-review

  108. Published

    Identification of Quaternary Structure and functional domains of the CI repressor from Bacteriophage TP901-1

    Pedersen, M., Lo Leggio, Leila, Grossmann, J. G., Larsen, Sine & Hammer, K., 2008, In: Journal of Molecular Biology. 373, p. 983-996

    Research output: Contribution to journalJournal articleResearchpeer-review

  109. Published

    Kinetics and stereochemistry of the Cellulomonas fimi ß-mannanase studied using 1H-NMR

    Anderson, L., Hägglund, P., Stoll, D., Lo Leggio, Leila, Drakenberg, T. & Stålbrand, H., 2008, In: Biocatalysis and Biotransformation. 26, p. 86-95

    Research output: Contribution to journalJournal articleResearchpeer-review

  110. Published

    Short strong hydrogen bonds in proteins: a case study of rhamnogalacturonan acetylesterase

    Langkilde, Annette Eva, Kristensen, S. M., Lo Leggio, Leila, Mølgaard, A., Jensen, Jan Halborg, Houk, A. R., Poulsen, Jens-Christian Navarro, Larsen, Sine & Kauppinen, S., 2008, In: Acta Crystallographica. Section D: Biological Crystallography. 64, p. 851-863

    Research output: Contribution to journalJournal articleResearchpeer-review

  111. Published

    Structure and function of enzymes in biomass degradation

    Welner, D. H., Jensen, M. H., McFarland, K. C., Poulsen, Jens-Christian Navarro, Otten, H., Salbo, R., Christensen, U., Harris, P., Larsen, Sine, Borchert, T., Christensen, L. L. H., Friis, E. P. & Lo Leggio, Leila, 2008, Biotechnology of lignocellulose degradation and Biomass Utilization - Mie Bioforum 2008. p. 349-355

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  112. 2007
  113. Published

    Alpha-Amylase from mung beans (Vigna radiata) - Correlation of biochemical properties and tertiary structure by homology modelling

    Tripathi, P., Lo Leggio, Leila, Mansfeld, J., Ulbrich-Hofmann, R. & Kayastha, A. M., 2007, In: Phytochemistry. 68, p. 1623-1631

    Research output: Contribution to journalJournal articleResearchpeer-review

  114. 2006
  115. Published

    Mapping of an Internal Protease Cleavage Site in the Ssy5p Component of the Amino Acid Sensor of Saccharomyces cerevisiae and Functional Characterization of the Resulting Pro- and Protease Domains by Gain-of-Function Genetics

    Poulsen, P., Lo Leggio, Leila & Kielland-Brandt, M. C., 2006, In: Eukaryotic Cell. 5, p. 601-608

    Research output: Contribution to journalJournal articleResearchpeer-review

  116. Published

    Structure of the Sulfolobus solfataricus alpha-glucosidase: Implications for domain conservation and substrate recognition in GH31

    Ernst, H. A., Lo Leggio, Leila, Willemoës, Martin, Leonard, G. A., Blum, P. & Larsen, Sine, 2006, In: Journal of Molecular Biology. 358, 4, p. 1106-24

    Research output: Contribution to journalJournal articleResearchpeer-review

  117. 2005
  118. Published

    Characterization of different crystal forms of the a-glucosidase MalA from Sulfolobus solfataricus

    Ernst, H. A., Willemoës, Martin, Lo Leggio, Leila, Leonard, G., Blum, P. & Larsen, Sine, 2005, In: Acta Crystallographica Section F. 61, p. 1039-1042

    Research output: Contribution to journalJournal articleResearchpeer-review

  119. Published

    Characterization of different crystal forms of the alpha-glucosidase MalA from Sulfolobus solfataricus

    Ernst, H. A., Willemoës, Martin, Lo Leggio, Leila, Leonard, G., Blum, P. & Larsen, Sine, 2005, In: Acta Crystallographica. Section F : Structural Biology and Crystallization Communications. 61, Pt 12, p. 1039-42 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  120. Published

    DNA-binding specificity and molecular functions of NAC transcription factors

    Olsen, A. N., Ernst, H. A., Lo Leggio, Leila & Skriver, Karen, 2005, In: Plant Science. 169, 4, p. 785-797

    Research output: Contribution to journalJournal articleResearchpeer-review

  121. Published

    NAC transcription factors: structurally distinct, functionally diverse

    Olsen, A. N., Ernst, H. A., Lo Leggio, Leila & Skriver, Karen, 2005, In: Trends in Plant Science. 10, 2, p. 79-87 8 p.

    Research output: Contribution to journalReviewResearch

  122. Published

    Probing the structure of glucan lyases by sequence analysis, circular dichroism and proteolysis

    Ernst, H. A., Lo Leggio, Leila, Yu, S., Finnie, C., Svensson, B. & Larsen, Sine, 2005, In: Biologia. 60, Suppl. 16, p. 149-159

    Research output: Contribution to journalJournal articleResearchpeer-review

  123. Published

    The Structure and Characterization of a Modular Endo-ß-1,4-mannanase from Cellulomonas fimi

    Le Nours, J., Anderson, L., Stoll, D., Stålbrand, H. & Lo Leggio, Leila, 2005, In: Biochemistry. 44, p. 12700-12708

    Research output: Contribution to journalJournal articleResearchpeer-review

  124. 2004
  125. Published

    Preliminary crystallographic analysis of the NAC domain of ANAC, a member of the plant-specific NAC transcription factor family

    Olsen, A. N., Ernst, H. A., Lo Leggio, Leila, Johansson, E. H., Larsen, Sine & Skriver, Karen, 2004, In: Acta Crystallographica. Section D: Biological Crystallography. 60, p. 112-115

    Research output: Contribution to journalJournal articleResearchpeer-review

  126. Published

    Structure and specificity of polysaccharidases belonging to clan GH-A

    Lo Leggio, Leila, Le Nours, J., Ryttersgaard, C., Kaneko, S., Fujimoto, Z., Kuno, A., Diertavitian, S. & Larsen, Sine, 2004, Biotechnology of Lignocellulose Degradation and Biomass Utilization. Ohmiya, K., Sakka, K., Karita, S., Kimura, T., Sakka, M. & Onishi, Y. (eds.). UNI Publishers Co., Ltd, p. 27-33

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  127. Published

    Structure of the conserved domain of ANAC, a member of the NAC family of transcription factors

    Ernst, H. A., Olsen, A. N., Skriver, Karen, Larsen, Sine & Lo Leggio, Leila, 2004, In: EMBO Reports. 5, p. 297-303

    Research output: Contribution to journalJournal articleResearchpeer-review

  128. Published

    The Structure of Endo-ß-1,4-galactanase from Bacillius licheniformis in Complex with Two Oligosaccharide Products

    Ryttersgaard, C., Le Nours, J., Lo Leggio, Leila, Thea Jørgensen, C., Lehmann Hylling Christensen, L., Bjørnvad, M. & Larsen, Sine, 2004, In: Journal of Molecular Biology. 341, p. 107-117

    Research output: Contribution to journalJournal articleResearchpeer-review

  129. 2003
  130. Published

    Crystallization and preliminary X-ray analysis of Alicyclobacillus acidocaldarius endoglucanase CelA

    Eckert, K., Ernst, H. A., Schneider, E., Larsen, Sine & Lo Leggio, Leila, 2003, In: Acta Crystallographica. Section D: Biological Crystallography. 51, p. 139-141

    Research output: Contribution to journalJournal articleResearchpeer-review

  131. Published

    Structures of two fungal ß-galactanases: Searching for the basis for temperature and pH optimum

    Le Nours, J., Ryttersgaard, C., Lo Leggio, Leila, Østergaard, P. R., Vedel Borchert, T., Lehmann Hylling Christensen, L. & Larsen, Sine, 2003, In: Protein Science. 12, p. 1195-1204

    Research output: Contribution to journalJournal articleResearchpeer-review

  132. Published

    The Structure and Specificity of Escherichia coli Maltose Acetyltransferase Give New Insight into the LacA Family of Acyltransferases

    Lo Leggio, Leila, Dal Degan, F., Poulsen, P., Møller Andersen, S. & Larsen, Sine, 2003, In: Biochemistry. 42, p. 5225-5235

    Research output: Contribution to journalJournal articleResearchpeer-review

  133. 2002
  134. Published

    Aspergillus aculeatus ß-1,4-Galactanase: Substrate Recognition and Relations to Other Glycoside Hydrolases in Clan GH-A

    Ryttersgaard, C., Lo Leggio, Leila, Coutinho, P. M., Henrissat, B. & Larsen, Sine, 2002, In: Biochemistry. 41, p. 15135-15143

    Research output: Contribution to journalJournal articleResearchpeer-review

  135. Published

    A structural model for the N-terminal N1 module of E. coli glycogen branching enzyme

    Lo Leggio, Leila, Ernst, H. A., Hilden, I. & Larsen, Sine, 2002, In: Biologia. 57, Suppl. 11, p. 109-118

    Research output: Contribution to journalJournal articleResearchpeer-review

  136. Published

    Crystallization and preliminary X-ray characterization of a thermostable pectate lyase from Thermotoga maritima

    Mc Donough, M. A., Ryttersgaard, C., Eskelund Bjørnvad, M., Lo Leggio, Leila, Schülein, M., Schrøder Glad, S. O. & Larsen, Sine, 2002, In: Acta Crystallographica. Section D: Biological Crystallography. 58, p. 709-711

    Research output: Contribution to journalJournal articleResearchpeer-review

  137. Published

    Gene cloning, sequencing, and characterization of a family 9 endoglucanase (CelA) with an unusual pattern of activity from the thermoacidophile Alicyclobacillus acidocaldarius ATCC27009

    Eckert, K., Zielinski, F., Lo Leggio, Leila & Schneider, E., 2002, In: Applied Microbiology and Biotechnology. 60, p. 428-436

    Research output: Contribution to journalJournal articleResearchpeer-review

  138. Published

    The 1.62 Å structure of Thermoascus aurantiacus endoglucanase: completing the structural picture of subfamilies in glycoside hydrolase family 5

    Lo Leggio, Leila & Larsen, Sine, 2002, In: FEBS Letters. 523, p. 103-108

    Research output: Contribution to journalJournal articleResearchpeer-review

  139. 2001
  140. Published

    Anisotropic refinement of the structure of Thermoascus aurantiacus xylanase I

    Teixeira, S., Lo Leggio, Leila, Pickersgill, R. W. & Cardin, C., 2001, In: Acta Crystallographica. Section D: Biological Crystallography. D57, p. 385-392

    Research output: Contribution to journalJournal articleResearchpeer-review

  141. Published

    Crystallization and preliminary X-ray analysis of maltose O-acetyltransferase

    Lo Leggio, Leila, Dal Degan, F., Poulsen, P., Oxenbøll Sørensen, S., Harlow, K. W., Harris, P. H. & Larsen, Sine, 2001, In: Acta Cryst.. D57, p. 1915-1918

    Research output: Contribution to journalJournal articleResearchpeer-review

  142. Published

    Substrate specificity and subsite mobility in T. aurantiacus xylanase 10A

    Lo Leggio, Leila, Kalogiannis, S., Eckert, K., Teixeira, S. C. M., Mahalingeswara, K. B., Andrei, C., Pickersgill, R. W. & Larsen, Sine, 2001, In: FEBS Letters. 509, p. 303-308

    Research output: Contribution to journalJournal articleResearchpeer-review

  143. 2000
  144. Published

    Characterisation and Crystallisation of an Active N-terminally Truncated Form of the Escherichia coli Glycogen Branching Enzyme

    Hilden, I., Lo Leggio, Leila, Larsen, Sine & Poulsen, P., 2000, In: European Journal of Biochemistry. 267, p. 2150-2155

    Research output: Contribution to journalJournal articleResearchpeer-review

  145. Published

    X-Ray Crystallographic Study of Xylopentaose Binding to Pseudomonas fluorescens Xylanase A.

    Lo Leggio, Leila, Jenkins, J., Harris, G. W. & Pickersgill, R. W., 2000, In: Proteins - Structure Function and Bioinformatics. 41, p. 362-373

    Research output: Contribution to journalJournal articleResearchpeer-review

  146. 1999
  147. Published

    High Resolution Structure and Sequence of T. aurantiacus Xylanase I: Implications for the Evolution of Thermostability in Family 10 Xylanases and Enzymes With ßa-Barrel Architecture

    Lo Leggio, Leila, Kalogiannis, S., Bhat, M. K. & Pickersgill, R. W., 1999, In: Proteins: Structure, Functions, and Genetics. 36, p. 295-306

    Research output: Contribution to journalJournal articleResearchpeer-review

  148. Published

    Xylanase-oligosaccharide interactions studied by a competitive enzyme assay

    Lo Leggio, Leila & Pickersgill, R. W., 1999, In: Enzyme and Microbial Technology. 25, p. 701-709

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 13810