Jonas Thue Treebak

Jonas Thue Treebak

Associate Professor

ORCID: 0000-0003-1488-7012

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  1. Published

    Age-dependent transition from islet insulin hypersecretion to hyposecretion in mice with the long QT-syndrome loss-of-function mutation Kcnq1-A340V

    Lubberding, Anniek Frederike, Zhang, J., Lundh, M., Nielsen, Thomas Svava, Søndergaard, M. S., Villadsen, M., Skovhøj, E. Z., Boer, G. A., Hansen, J. B., Thomsen, Morten Bækgaard, Treebak, Jonas Thue, Holst, Jens Juul, Kanters, Jørgen K., Mandrup-Poulsen, Thomas, Jespersen, Thomas, Emanuelli, Brice & Torekov, Signe Sørensen, 2021, In: Scientific Reports. 11, 1, 14 p., 12253.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Sucrose counteracts the anti-inflammatory effect of fish oil in adipose tissue and increases obesity development in mice

    Ma, Tao, Liaset, B., Hao, Q., Petersen, R. K., Fjære, E., Ngo, H. T., Lillefosse, H. H., Jørgensen, Stine Ringholm, Sonne, Si Brask, Treebak, Jonas Thue, Pilegaard, Henriette, Frøyland, L., Kristiansen, Karsten & Madsen, L., 2011, In: P L o S One. 6, 6, 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Genetic impairment of AMPK{alpha}2 signaling does not reduce muscle glucose uptake during treadmill exercise in mice

    Maarbjerg, S. J., Jørgensen, S. B., Rose, A. J., Jeppesen, J., Jensen, Thomas Elbenhardt, Treebak, Jonas Thue, Birk, Jesper Bratz, Schjerling, Peter, Wojtaszewski, Jørgen F P & Richter, Erik A., 2009, In: American Journal of Physiology: Endocrinology and Metabolism. 297, 4, p. E924-E934 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p

    Madsen, C. T., Sylvestersen, K. B., Young, C., Buch-Larsen, Sara Charlotte, Poulsen, J. W., Andersen, M. A., Palmqvist, E. A., Hey-Mogensen, M., Jensen, P. B., Treebak, Jonas Thue, Lisby, Michael & Nielsen, Michael Lund, 2015, In: Nature Communications. 6, 12 p., 7726.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia

    Membrez, M., Migliavacca, E., Christen, S., Yaku, K., Trieu, J., Lee, A. K., Morandini, F., Giner, M. P., Stiner, J., Makarov, M. V., Garratt, E. S., Vasiloglou, M. F., Chanvillard, L., Dalbram, E., Ehrlich, A. M., Sanchez-Garcia, J. L., Canto, C., Karagounis, L. G., Treebak, J. T., Migaud, M. E. & 15 others, Heshmat, R., Razi, F., Karnani, N., Ostovar, A., Farzadfar, F., Tay, S. K. H., Sanders, M. J., Lillycrop, K. A., Godfrey, K. M., Nakagawa, T., Moco, S., Koopman, R., Lynch, G. S., Sorrentino, V. & Feige, J. N., 2024, In: Nature Metabolism. 6, 3, p. 433–447

    Research output: Contribution to journal › Letter › Research › peer-review

  6. Published

    Insulin stimulation regulates AS160 and TBC1D1 phosphorylation sites in human skeletal muscle

    Middelbeek, R. J. W., Chambers, M. A., Tantiwong, P., Treebak, Jonas Thue, An, D., Hirshman, M. F., Musi, N. & Goodyear, L. J., Jun 2013, In: Nutrition and Diabetes. 3, 74, p. e74

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    ARDD 2020: from aging mechanisms to interventions

    Mkrtchyan, G. V., Abdelmohsen, K., Andreux, P., Bagdonaite, I., Barzilai, N., Brunak, S., Cabreiro, F., Cabo, R. D., Campisi, J., Cuervo, A. M., Demaria, M., Ewald, C. Y., Fang, E. F., Faragher, R., Ferrucci, L., Freund, A., Silva-García, C. G., Georgievskaya, A., Gladyshev, V. N., Glass, D. J. & 46 others, Gorbunova, V., Grey, A. D., He, W. W., Hoeijmakers, J., Hoffmann, Eva, Horvath, S., Houtkooper, R. H., Jensen, Majken Karoline, Jensen, M. B., Kane, A., Kassem, Moustapha Saad El-Deen, Keizer, P. D., Kennedy, B., Karsenty, G., Lamming, D. W., Lee, K. F., MacAulay, Nanna, Mamoshina, P., Mellon, J., Molenaars, M., Moskalev, A., Mund, Andreas, Niedernhofer, L., Osborne, Brenna, Pak, H. H., Parkhitko, A., Raimundo, N., Rando, T. A., Rasmussen, Lene Juel, Reis, C., Riedel, C. G., Franco-Romero, A., Schumacher, B., Sinclair, D. A., Suh, Y., Taub, P. R., Toiber, D., Treebak, Jonas Thue, Valenzano, D. R., Verdin, E., Vijg, J., Young, S., Zhang, L., Bakula, Daniela Janina, Zhavoronkov, A. & Scheibye-Knudsen, Morten, 2020, In: Aging. 12, 24, p. 24486-24503 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes

    Moltke, I., Grarup, N., Jørgensen, M. E., Bjerregaard, P., Treebak, J. T., Fumagalli, M., Korneliussen, T. S., Andersen, M. A., Nielsen, T. S., Krarup, N. T., Gjesing, A. M. P., Zierath, J. R., Linneberg, A., Wu, X., Sun, G., Jin, X., Al-Aama, J., Wang, J., Borch-Johnsen, K., Pedersen, O. & 3 others, Nielsen, R., Albrechtsen, Anders & Hansen, Torben, 2014, In: Nature. 512, 7513, p. 190-193 4 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  9. Published

    NAMPT-mediated NAD+ biosynthesis is indispensable for adipose tissue plasticity and development of obesity

    Nielsen, K. N., Peics, J., Ma, Tao, Karavaeva, Iuliia, Dall, M., Chubanava, Sabina, Basse, A. L., Dmytriyeva, O., Treebak, Jonas Thue & Gerhart-Hines, Zach, May 2018, In: Molecular Metabolism. 11, p. 178-188 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    From trainee to trainer: lessons Learned through implementation of a dual-catheter model in mice

    Nielsen, Thomas Svava & Treebak, Jonas Thue, 2022, In: Laboratory Animals. 56, S1, p. 105 1 p., S5C1.2.

    Research output: Contribution to journal › Conference abstract in journal › Research

  11. Published

    Effect of resveratrol on insulin action in primary myotubes from lean individuals and individuals with severe obesity

    Park, S., Jevtovic, F., Krassovskaia, P. M., Chaves, A. B., Zheng, D., Treebak, Jonas Thue & Houmard, J. A., 2024, In: American Journal of Physiology - Endocrinology and Metabolism. 326, 3, p. E398-E406 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Electrical pulse stimulation induces differential responses in insulin action in myotubes from severely obese individuals

    Park, S., Turner, K. D., Zheng, D., Brault, J. J., Zou, K., Chaves, A. B., Nielsen, Thomas Svava, Tanner, C. J., Treebak, Jonas Thue & Houmard, J. A., 2019, In: The Journal of Physiology. 597, 2, p. 449-466

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Fiber type-specific effects of acute exercise on insulin-stimulated AS160 phosphorylation in insulin-resistant rat skeletal muscle

    Pataky, M. W., Van Acker, S. L., Dhingra, R., Freeburg, M. M., Arias, E. B., Oki, K., Wang, H., Treebak, Jonas Thue & Cartee, G. D., 2019, In: American Journal of Physiology: Endocrinology and Metabolism. 317, 6, p. E984-E998

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Effects of Exercise on Lipid-Induced Insulin Resistance in Human Skeletal Muscle-Signaling at the Level of TBC1D4

    Pehmoller, C., Brandt, N., Birk, Jesper Bratz, Treebak, Jonas Thue, Hoeg, L. D., Sjoberg, K. A., Kiens, Bente, Richter, Erik A. & Wojtaszewski, Jørgen F P, 2010, In: Diabetes.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Genetic disruption of AMPK signaling abolishes both contraction- and insulin-stimulated TBC1D1 phosphorylation and 14-3-3 binding in mouse skeletal muscle

    Pehmøller, C., Treebak, Jonas Thue, Birk, Jesper Bratz, Chen, S., Mackintosh, C., Hardie, D. G., Richter, Erik A. & Wojtaszewski, Jørgen F P, 2009, In: American Journal of Physiology: Endocrinology and Metabolism. 297, 3, p. E665-E675 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Oral supplementation of nicotinamide riboside alters intestinal microbial composition in rats and mice, but not humans

    Peluso, A. A., Lundgaard, A. T., Babaei, P., Mousovich-Neto, F., Rocha, A. L., Damgaard, M. V., Bak, E. G., Gnanasekaran, T., Dollerup, O. L., Trammell, S. A. J., Nielsen, T. S., Kern, T., Abild, C. B., Sulek, K., Ma, T., Gerhart-Hines, Z., Gillum, M. P., Arumugam, M., Ørskov, C., McCloskey, D. & 4 others, Jessen, N., Herrgård, M. J., Mori, M. A. S. & Treebak, Jonas Thue, 2023, In: npj Aging. 9, 21 p., 7.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Age‐dependent decline of NAD+ - universal truth or confounded consensus?

    Peluso, A. A., Damgaard, Mads Vargas, Mori, M. A. S. & Treebak, Jonas Thue, 2021, In: Nutrients. 14, 1, 101.

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    Metabolic plasticity and obesity-associated changes in diurnal postexercise metabolism in mice

    Pendergrast, L. A., Ashcroft, Stephen Paul, Ehrlich, Amy M, Treebak, Jonas Thue, Krook, A., Dollet, L. & Zierath, Juleen R, 2024, In: Metabolism: Clinical and Experimental. 155, 12 p., 155834.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Time of day determines postexercise metabolism in mouse adipose tissue

    Pendergrast, L. A., Lundell, L. S., Ehrlich, Amy M, Ashcroft, Stephen Paul, Schönke, M., Basse, A. L., Krook, A., Treebak, Jonas Thue, Dollet, L. & Zierath, Juleen R, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 8, e2218510120.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Hepatic NAD salvage pathway is enhanced in mice on a high-fat diet

    Penke, M., Larsen, P. S., Schuster, S., Dall, M., Jensen, Benjamin Anderschou Holbech, Gorski, T., Meusel, A., Richter, S., Vienberg, S. G., Treebak, Jonas Thue, Kiess, W. & Garten, A., 2015, In: Molecular and Cellular Endocrinology. 412, p. 65-72 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Hepatic NAD Metabolism Is Dysregulated By an Excessive Supply of Lipids

    Penke, M., Treebak, Jonas Thue, Schuster, S., Gorski, T., Garten, A. & Kiess, W., 2014, In: Endocrine Reviews.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Genes controlling the activation of natural killer lymphocytes are epigenetically remodeled in intestinal cells from germ-free mice

    Poupeau, A., Garde, C., Sulek, K., Citirikkaya, K., Treebak, Jonas Thue, Arumugam, Mani, Simar, D., Olofsson, L. E., Bäckhed, F. & Barrès, Romain, 2019, In: F A S E B Journal. 33, 2, p. 2719-2731 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Perturbations in the p53/miR-34a/SIRT1 pathway in the R6/2 Huntington's disease model

    Reynolds, R. H., Petersen, M. H., Willert, C. W., Heinrich, M., Nymann, N., Dall, M., Treebak, Jonas Thue, Björkqvist, M., Silahtaroglu, Asli, Hasholt, Lis Frydenreich & Nørremølle, Anne, 2018, In: Molecular and Cellular Neuroscience. 88, p. 118-129

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Compound- and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle

    Rhein, P., Desjardins, E. M., Rong, P., Ahwazi, D., Bonhoure, N., Stolte, J., Santos, M. D., Ovens, A. J., Ehrlich, A. M., Sanchez Garcia, J. L., Ouyang, Q., Yabut, J. M., Kjolby, M., Membrez, M., Jessen, N., Oakhill, J. S., Treebak, J. T., Maire, P., Scott, J. W., Sanders, M. J. & 4 others, Descombes, P., Chen, S., Steinberg, G. R. & Sakamoto, Kei, 2021, In: Molecular Metabolism. 51, 18 p., 101228.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    The aromatic amino acid sensor GPR142 controls metabolism through balanced regulation of pancreatic and gut hormones

    Rudenko, Olga, Shang, J., Munk, A., Ekberg, J. P., Petersen, N., Engelstoft, M. S., Egerod, Kristoffer Lihme, Hjorth, Siv Annegrethe, Wu, M., Feng, Y., Zhou, Y., Mokrosinski, J., Thams, P., Reimann, F., Gribble, F., Rehfeld, Jens Frederik, Holst, Jens Juul, Treebak, Jonas Thue, Howard, A. D. & Schwartz, Thue W., 2019, In: Molecular Metabolism. 19, p. 49-64 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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