Jens Lykkesfeldt
Professor
- 2014
- Published
Melatonin does not affect oxidative/inflammatory biomarkers in a closed-chest porcine model of acute myocardial infarction
Halladin, N. L., Busch, S. V. E., Jensen, S. E., Aarøe, J., Kjærgaard, B., Heegaard, P. M. H., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 2014, In: In Vivo. 28, p. 483-488 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does vitamin C deficiency affect cognitive development and function?
Hansen, S. N., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2014, In: Nutrients. 6, 9, p. 3818-3846 29 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does vitamin C deficiency promote fatty liver disease development?
Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2014, In: Nutrients. 6, 12, p. 5473-5499 27 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Effect of insulin-induced hypoglycaemia on the central nervous system: evidence from experimental studies
Jensen, Vivi Flou Hjorth, Bøgh, I. B. & Lykkesfeldt, Jens, 2014, In: Journal of Neuroendocrinology. 26, 3, p. 123-150 28 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of insulin-induced hypoglycaemia on the peripheral nervous system: focus on adaptive mechanisms, pathogenesis and histopathological changes
Jensen, Vivi Flou Hjorth, Mølck, A., Bøgh, I. B. & Lykkesfeldt, Jens, 2014, In: Journal of Neuroendocrinology. 26, 8, p. 482-496 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats
Knudsen, K. B., Northeved, H., Gjetting, T., Permin, A., Andresen, T. L., Wegener, K. M., Rye Lam, H. & Lykkesfeldt, Jens, 2014, In: Journal of Nanoparticle Research. 16, 1, 11 p., 2221.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential toxicological response to positively and negatively charged nanoparticles in the rat brain
Knudsen, K. B., Northeved, H., Ek, P. K., Permin, A., Andresen, T. L., Larsen, S., Wegener, K. M., Lam, H. R. & Lykkesfeldt, Jens, 2014, In: Nanotoxicology. 8, 7, p. 764-774 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vitamin C
Lykkesfeldt, Jens, Michels, A. J. & Frei, B., 2014, In: Advances in Nutrition. 5, 1, p. 16-18 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies
Mortensen, A. & Lykkesfeldt, Jens, 2014, In: Nitric Oxide: Biology and Chemistry. 36, p. 51-57 7 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Positive charge, negative effect: the impact of cationic nanoparticles in the brain
Møller, Peter & Lykkesfeldt, Jens, Jul 2014, In: Nanomedicine. 9, 10, p. 1441-3 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Chronic vitamin C deficiency promotes redox imbalance in the brain but does not alter sodium-dependent vitamin C transporter 2 expression
Paidi, M. D., Schjoldager, J. G., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Nutrients. 6, 5, p. 1809-1822 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prenatal vitamin C deficiency results in differential levels of oxidative stress during late gestation in foetal guinea pig brains
Paidi, M. D., Schjoldager, J. G., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Redox Biology. 2, p. 361-367 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biopterin status in dogs with myxomatous mitral valve disease is associated with disease severity and cardiovascular risk factors
Reimann, Maria Josefine, Häggström, J., Mortensen, A., Lykkesfeldt, Jens, Møller, J. E., Falk, B. T. & Olsen, Lisbeth Høier, 2014, In: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. 28, 5, p. 1520-1526 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo vitamin C deficiency in guinea pigs increases ascorbate transporters in liver but not kidney and brain
Søgaard, D., Lindblad, M. M., Paidi, M. D., Andersen, S. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Nutrition Research. 34, 7, p. 639-645 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The kidneys play an important role in the clearance of rFVIIa in rats
Vestergaard, Bill, Appa, R. S., Lykkesfeldt, Jens & Agersø, H., 2014, In: Thrombosis Research. 133, 6, p. 1124-1129 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Circadian Variation in the Response to Experimental Endotoxemia and Modulatory Effects of Exogenous Melatonin
Alamili, M., Klein, M., Lykkesfeldt, Jens, Rosenberg, J. & Gögenur, I., 2013, In: Chronobiology International. 30, 9, p. 1174-1180 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whey protein reduces early life weight gain in mice fed a high-fat diet
Christensen, B. T., Hellgren, L., Lykkesfeldt, Jens, Sejrsen, K., Jeamet, A., Rune, Ida, Ellekilde, M., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2013, In: PLOS ONE. 8, 8, 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased systemic oxidatively generated DNA and RNA damage in schizophrenia
Jørgensen, A., Brødbæk, K., Fink-Jensen, Anders, Knorr, U., Greisen Søndergaard, M., Henriksen, T., Weimann, A., Jepsen, P., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen & Jørgensen, Martin Balslev, 2013, In: Psychiatry Research. 209, 3, p. 417–423 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of vitamin C homeostasis during deficiency
Lindblad, M. M., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Nutrients. 5, 8, p. 2860-2879 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Guinea pig ascorbate status predicts tetrahydrobiopterin plasma concentration and oxidation ratio in vivo
Mortensen, A., Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Nutrition Research. 33, 10, p. 859-867 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinetics of acid-induced degradation of tetra- and dihydrobiopterin in relation to their relevance as biomarkers of endothelial function
Mortensen, A. & Lykkesfeldt, Jens, 2013, In: Biomarkers. 18, 1, p. 55-62 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Translational aspects of rectal evoked potentials: a comparative study in rats and humans
Nissen, T. D., Brock, C., Graversen, C., J. Coen, S., Hultin, L., Aziz, Q., Lykkesfeldt, Jens & Drewes, A. M., 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 305, p. G119-G128 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prolonged effect of a new O-glycoPEGylated FVIII (N8-GP) in a murine saphenous vein bleeding model
Pastoft, A. E., Ezban, M., Tranholm, M., Lykkesfeldt, Jens & Lauritzen, B., 2013, In: Haemophilia Online. 19, 6, p. 913-919 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ampicillin-improved glucose tolerance in diet-induced obese C57BL/6NTac mice is age dependent
Rune, Ida, Hansen, Camilla Hartmann Friis, Ellekilde, M., Nielsen, Dennis Sandris, Skovgaard, K., Rolin, B. C., Lykkesfeldt, Jens, Josefsen, K., Christensen, B. T., Kihl, Pernille & Hansen, Axel Kornerup, 2013, In: Experimental Diabetes Research. 2013, 13 p., 319321.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prolonged maternal vitamin C deficiency overrides preferential fetal ascorbate transport but does not influence perinatal survival in guinea pigs
Schjoldager, J. G., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: British Journal of Nutrition. 110, 9, p. 1573-1579 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does vitamin C deficiency increase lifestyle-associated vascular disease progression? evidence based on experimental and clinical studies
Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Antioxidants & Redox Signaling. 19, 17, p. 2084-2104 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nephrectomized and hepatectomized animal models as tools in preclinical pharmacokinetics
Vestergaard, Bill, Agersø, H. & Lykkesfeldt, Jens, 2013, In: Basic & Clinical Pharmacology & Toxicology Online. 113, 2, p. 75-86 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Vitamin C and its role in brain development and cognition
Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2012, Nutrition and mental performance: a develomental perspective. Riby, L., Smith, M. & Foster, J. (eds.). Palgrave Macmillan, p. 29-52 24 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Ascorbate status modulates reticuloendothelial iron stores and response to deferasirox iron chelation in ascorbate-deficient rats
Brewer, C., Otto-Duessel, M., Lykkesfeldt, Jens, Nick, H. & Wood, J. C., 2012, In: Experimental Hematology. 40, 10, p. 820-827 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
What is the optimum intake of vitamin C in humans?
Frei, B., Birlouez-Aragon, I. & Lykkesfeldt, Jens, 2012, In: Critical Reviews in Food Science and Nutrition. 52, 9, p. 815-829 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Poor antioxidant status exacerbates oxidative stress and inflammatory response to Pseudomonas aeruginosa lung infection in Guinea Pigs
Jensen, Peter Østrup, Lykkesfeldt, Jens, Bjarnsholt, Thomas, Hougen, H. P., Høiby, Niels & Ciofu, Oana, 2012, In: Basic & Clinical Pharmacology & Toxicology. 110, 4, p. 353-358 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ascorbate and dehydroascorbic acid as biomarkers of oxidative stress: validity of clinical data depends on vacutainer system used
Lykkesfeldt, Jens, 2012, In: Nutrition Research. 32, 1, p. 66-69 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxidative stress response after laparoscopic versus conventional sigmoid resection: a randomized, double-blind clinical trial
Madsen, M. T., Kücükakin, B., Lykkesfeldt, Jens, Rosenberg, J. & Gögenur, I., 2012, In: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques. 22, 3, p. 215-219 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A sensitive venous bleeding model in haemophilia A mice: effects of two recombinant FVIII products (N8 and Advate®)
Pastoft, A. E., Lykkesfeldt, Jens, Ezban, M., Tranholm, M., Whinna, H. C. & Lauritzen, B., 2012, In: Haemophilia. 18, 5, p. 782-788 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chronic vitamin C deficiency does not accelerate oxidative stress in ageing brains of guinea pigs
Tveden-Nyborg, Pernille, Andersen, S. H., Miyashita, N., Moos, T., Poulsen, Henrik Enghusen & Lykkesfeldt, Jens, 2012, In: Basic & Clinical Pharmacology & Toxicology Online. 110, 6, p. 524-529 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal vitamin C deficiency during pregnancy persistently impairs hippocampal neurogenesis in offspring of guinea pigs
Tveden-Nyborg, Pernille, Vogt, L., Schjoldager, J. G., Jeannet, N., Andersen, S. H., Paidi, M. D., Christen, S. & Lykkesfeldt, Jens, 2012, In: P L o S One. 7, 10, 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of vitamin C and E supplementation on IL-6 in response to training
Yfanti, C., Fischer, C. P., Nielsen, S., Åkerström, T., Nielsen, A. R., Veskoukis, A. S., Kouretas, D., Lykkesfeldt, Jens, Pilegaard, Henriette & Pedersen, Bente Klarlund, 2012, In: Journal of Applied Physiology. 112, 6, p. 990-1000 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Vitamin C - ascorbic acid
Frikke-Schmidt, H., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens, Drake, V. J. & Frei, B., 28 Feb 2011, Vitamins in the Prevention of Human Diseases. Walter de Gruyter GmbH and Co. KG, p. 323-362 40 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Effect of vitamin C and iron chelation on diesel exhaust particle and carbon black induced oxidative damage and cell adhesion molecule expression in human endothelial cells
Frikke-Schmidt, H. R., Roursgaard, Martin, Lykkesfeldt, Jens, Loft, Steffen, Nøjgaard, J. K. & Møller, Peter, 2011, In: Toxicology Letters. 203, 3, p. 181-189 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High dietary fat and cholesterol exacerbates chronic vitamin C deficiency in guinea pigs
Frikke-Schmidt, H. R., Tveden-Nyborg, Pernille, Birck, M. M. & Lykkesfeldt, Jens, 2011, In: British Journal of Nutrition. 105, 1, p. 54-61 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vitamin C in human nutrition
Frikke-Schmidt, H. R., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2011, Vitamins in the prevention of human diseases. Herrmann, W. & Obeid, R. (eds.). De Gruyter, p. 323-362 40 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Storage-induced increase in biomarkers of oxidative stress and inflammation in red blood cell components
Kücükakin, B., Kocak, V., Lykkesfeldt, Jens, Nielsen, H. J., Magnussen, K., Rosenberg, Jacob & Gögenür, I., 2011, In: Scandinavian Journal of Clinical & Laboratory Investigation. 71, 4, p. 299-303 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reply to Hemilä by Lykkesfeldt and Poulsen
Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2011, In: British Journal of Nutrition. 105, 3, p. 488 1 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Animal models in pharmacology and toxicology
Meyer, O. A., Svendsen, O. & Lykkesfeldt, Jens, 2011, Handbook of laboratory animal science: volume II: Animal models. Hau, J. & J. Schapiro, S. (eds.). 3. ed. ed. CRC Press, Vol. 2. p. 149-184 36 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Fluctuating hyperglycaemia increases oxidative stress response in lean rats compared to sustained hyperglycaemia despite lower glycaemic exposure
Rakipovski, G., Raun, K. & Lykkesfeldt, Jens, 2011, In: Diabetes and Vascular Disease Research. 8, 4, p. 295-298 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of antioxidant supplementation on insulin sensitivity in response to endurance exercise training
Yfanti, C., Nielsen, A. R., Åkerström, T., Nielsen, S., Rose, A. J., Richter, Erik A., Lykkesfeldt, Jens, Fischer, C. P. & Pedersen, Bente Klarlund, 2011, In: American Journal of Physiology: Endocrinology and Metabolism. 300, 5, p. E761-E770 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Obese Prone Rats on high- and low-fat diets gain weight equally
Christensen, B. T., Hellgren, L., Sejrsen, K., Lykkesfeldt, Jens & Hansen, Axel Kornerup, 2010.Research output: Contribution to conference › Poster › Research
- Published
Keeping the intracellular vitamin C at a physiologically relevant level in endothelial cell culture
Frikke-Schmidt, H. R. & Lykkesfeldt, Jens, 2010, In: Analytical Biochemistry. 397, 1, p. 135-137 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4231856
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Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
5764
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Increased systemic oxidatively generated DNA and RNA damage in schizophrenia
Research output: Contribution to journal › Journal article › Research › peer-review
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4601
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Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies
Research output: Contribution to journal › Review › Research › peer-review
Published