Jens Lykkesfeldt
Professor
- 2017
- Published
Assessment of implantable infusion pumps for continuous infusion of human insulin in rats: potential for group housing
Jensen, Vivi Flou Hjorth, Molck, A., Martensson, M., Strid, M. A., Chapman, M., Lykkesfeldt, Jens & Bogh, I. B., 2017, In: Laboratory Animals. 51, 3, p. 273-283Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chronic Hyperinsulinaemic Hypoglycaemia in Rats Is Accompanied by Increased Body Weight, Hyperleptinaemia, and Decreased Neuronal Glucose Transporter Levels in the Brain
Jensen, Vivi Flou Hjorth, Molck, A., Chapman, M., Alifrangis, L., Andersen, L., Lykkesfeldt, Jens & Bogh, I. B., 2017, In: International Journal of Endocrinology. 2017, 14 p., 7861236.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of High Inspiratory Oxygen Fraction on Endothelial Dysfunction in Healthy Volunteers: A Randomized Controlled Cross-over Pilot Study
Larsen, M. H. H., Ekeløf, S., Kokotovic, D., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Gögenur, I., 2017, In: Anesthesia and Analgesia. 125, 5, p. 1793–1796Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Markers of Oxidative Stress in Dogs with Myxomatous Mitral Valve Disease are Influenced by Sex, Neuter Status, and Serum Cholesterol Concentration
Reimann, Maria Josefine, Haggstrom, J., Moller, J. E., Lykkesfeldt, Jens, Falk, T. & Olsen, Lisbeth Høier, 2017, In: Journal of Veterinary Internal Medicine. 31, 2, p. 295-302 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Poor vitamin C status late in pregnancy is associated with increased risk of complications in type 1 diabetic women: A cross-sectional study
Juhl, B., Lauszus, F. F. & Lykkesfeldt, Jens, 2017, In: Nutrients. 9, 3, 9 p., 186.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vitamin C deficiency reduces muscarinic receptor coronary artery vasoconstriction and plasma tetrahydrobiopterin concentration in guinea pigs
Skovsted, Gry Freja, Tveden-Nyborg, Pernille, Lindblad, M. M., Hansen, S. N. & Lykkesfeldt, Jens, 2017, In: Nutrients. 9, 7, 14 p., 691.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Weekly ascorbic acid infusion in castration-resistant prostate cancer patients: A single-arm phase II trial
Nielsen, Torben Kjær, Højgaard, M., Andersen, Jon Thor Trærup, Jørgensen, N. R., Zerahn, B., Kristensen, B., Henriksen, T., Lykkesfeldt, Jens, Mikines, K. J. & Poulsen, Henrik Enghusen, 2017, In: Translational Andrology and Urology. 6, 3, p. 517-528 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Dyslipidemia: Obese or Not Obese-That Is Not the Question
Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, Dec 2016, In: Current Obesity Reports. 5, 4, p. 405-412Research output: Contribution to journal › Review › Research › peer-review
- Published
Oxidative costs of reproduction in mouse strains selected for different levels of food intake and which differ in reproductive performance
Jothery, A. H. A., Vaanholt, L. M., Mody, N., Arnous, A., Lykkesfeldt, Jens, Bunger, L., Hill, W. G., Mitchell, S. E., Allison, D. B. & Speakman, J. R., 14 Nov 2016, In: Scientific Reports. 6, 12 p., 36353 .Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro toxicity of cationic micelles and liposomes in cultured human hepatocyte (HepG2) and lung epithelial (A549) cell lines
Roursgaard, Martin, Knudsen, K. B., Northeved, H., Persson, M., Christensen, T., Kumar, P. E. K., Permin, A., Andresen, T. L., Gjetting, T., Lykkesfeldt, Jens, Vesterdal, L. K., Loft, Steffen & Møller, Peter, Oct 2016, In: Toxicology in Vitro. 36, p. 164-171 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is Diabetes Associated with Lower Vitamin C Status in Pregnant Women? A Prospective Study
Juhl, B., Lauszus, F. F. & Lykkesfeldt, Jens, Oct 2016, In: International Journal for Vitamin and Nutrition Research. 86, 5-6, p. 184-189Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cardiovascular health effects of oral and pulmonary exposure to multi-walled carbon nanotubes in ApoE-deficient mice
Christophersen, D. V., Raun Jacobsen, N., Guerra Andersen, M. H., Connell, S. P., Barfod, K. K., Thomsen, Morten Bækgaard, Miller, M. R., Duffin, R., Lykkesfeldt, Jens, Vogel, U. B., Wallin, E. H. R., Loft, Steffen, Roursgaard, Martin & Møller, Peter, 14 Sep 2016, In: Toxicology. 371, p. 29-40 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rodent model choice has major impact on variability of standard preclinical readouts associated with diabetes and obesity research
Jensen, Victoria Svop, Porsgaard, T., Lykkesfeldt, Jens & Hvid, H., 15 Aug 2016, In: American Journal of Translational Research. 8, 8, p. 3574-3584Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simultaneous quantification of monoamine neurotransmitters and their biogenic metabolites intracellularly and extracellularly in primary neuronal cell cultures and in sub-regions of guinea pig brain
Schou-Pedersen, A. M. V., Hansen, S. N., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 15 Aug 2016, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1028, p. 222-230 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Strategies for Using Plagiarism Software in the Screening of Incoming Journal Manuscripts: Recommendations Based on a Recent Literature Survey
Lykkesfeldt, Jens, Aug 2016, In: Basic & Clinical Pharmacology & Toxicology. 119, 2, p. 161-164Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal vitamin C deficiency does not reduce hippocampal volume and beta-tubulin III intensity in prenatal Guinea pigs
Hansen, S. N., Schjoldager, J. G., Paidi, M. D., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, Jul 2016, In: Nutrition Research. 36, 7, p. 696-702Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The kidneys play a central role in the clearance of rhGH in rats
Vestergaard, Bill, Thygesen, P., Kreilgaard, M., Fels, J. J., Lykkesfeldt, Jens & Agerso, H., 30 Apr 2016, In: European Journal of Pharmaceutical Sciences. 86, p. 29-33Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Normal Weight Dyslipidemia: Is It All About the Liver?
Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, Mar 2016, In: Obesity. 24, 3, p. 556-567 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Diet-induced dyslipidemia leads to nonalcoholic fatty liver disease and oxidative stress in guinea pigs
Tveden-Nyborg, Pernille, Birck, M. M., Ipsen, David Højland, Thiessen, T. S., Feldmann, L. D. B., Lindblad, M. M., Jensen, Henrik Elvang & Lykkesfeldt, Jens, 1 Feb 2016, In: Translational Research. 168, p. 146-160 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pulsatile Hyperglycaemia Induces Vascular Oxidative Stress and GLUT 1 Expression More Potently than Sustained Hyperglycaemia in Rats on High Fat Diet
Rakipovski, G., Lykkesfeldt, Jens & Raun, K., 20 Jan 2016, In: P L o S One. 11, 1, e0147412.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Histopathological nerve and skeletal muscle changes in rats subjected to persistent insulin-induced hypoglycemia
Jensen, Vivi Flou Hjorth, Mølck, A., Heydenreich, A., Jensen, K. J., Bertelsen, L. O., Alifrangis, L., Andersen, L., Søeborg, H., Chapman, M., Lykkesfeldt, Jens & Bøgh, I. B., Jan 2016, In: Toxicologic Pathology. 29, 1, p. 17-30 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
L-dehydroascorbic acid can substitute L-ascorbic acid as dietary vitamin C source in guinea pigs
Frikke-Schmidt, H. R., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2016, In: Redox Biology. 7, p. 8-13 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does Glucagon-like Peptide-1 Ameliorate Oxidative Stress in Diabetes? Evidence Based on Experimental and Clinical Studies
Petersen, Karen Ekkelund, Rakipovski, G., Raun, K. & Lykkesfeldt, Jens, 2016, In: Current Diabetes Reviews. 12, 4, p. 331-358 28 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
High-fat but not sucrose intake is essential for induction of dyslipidemia and non-alcoholic steatohepatitis in guinea pigs
Ipsen, David Højland, Tveden-Nyborg, Pernille, Rolin, B., Rakipovski, G., Beck, M., Mortensen, L. W., Færk, L., Heegaard, P. M. H., Møller, Peter & Lykkesfeldt, Jens, 2016, In: Nutrition & Metabolism. 13, p. 51Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modulating the gut microbiota improves glucose tolerance, lipoprotein profile and atherosclerotic plaque development in ApoE-deficient mice
Rune, Ida, Rolin, B., Larsen, C. S., Nielsen, Dennis Sandris, Kanter, J. E., Bornfeldt, K. E., Lykkesfeldt, Jens, Buschard, K., Kirk, R. K., Christoffersen, B., Fels, J. J., Josefsen, K., Kihl, Pernille & Hansen, Axel Kornerup, 2016, In: P L o S One. 11, 1, 16 p., e0146439.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simvastatin and oxidative stress in humans: A randomized, double-blinded, placebo-controlled clinical trial
Rasmussen, S. T., Andersen, Jon Thor Trærup, Nielsen, T. K., Cejvanovic, V., Petersen, K. M., Henriksen, T., Weimann, A., Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2016, In: Redox Biology. 9, p. 32-38Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vitaminer til hjernen
Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2016, In: Aktuel Naturvidenskab. 2016, 4, p. 8-11 4 p.Research output: Contribution to journal › Journal article › Research
- 2015
- Published
Thick methacrylate sections devoid of lost caps simplify stereological quantifications based on the optical fractionator design
Andersen, S. H., Lykkesfeldt, Jens & Larsen, J. O., 15 Sep 2015, In: Anatomical Record. 298, 12, p. 2141-2150 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chronic dyslipidemia induces fatty liver disease in Guinea pigs
Tveden-Nyborg, Pernille, Birck, M. M., Ipsen, David Højland & Lykkesfeldt, Jens, Jul 2015, In: Atherosclerosis. 241, 1, p. e119-e120 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Lower limb ischaemia and reperfusion injury in healthy volunteers measured by oxidative and inflammatory biomarkers
Halladin, N. L., Busch, S. V. E., Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 10 Apr 2015, In: Perfusion. 30, 1, p. 64-70 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection: a pilot study
Skov, M., Pressler, T., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen, Jensen, Peter Østrup, Johansen, Helle Krogh, Qvist, T., Kræmer, D., Høiby, Niels & Ciofu, Oana, Mar 2015, In: Journal of Cystic Fibrosis. 14, 2, p. 211-218 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo toxicity of cationic micelles and liposomes
Knudsen, K. B., Northeved, H., Kumar Ek, P., Permin, A., Gjetting, T., Andresen, T. L., Larsen, S., Wegener, K. M., Lykkesfeldt, Jens, Jantzen, K., Loft, Steffen, Møller, Peter & Roursgaard, Martin, 25 Feb 2015, In: Nanomedicine: Nanotechnology, Biology and Medicine. 11, 2, p. 467-477 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Asymmetric dimethylarginine in somatically healthy schizophrenia patients treated with atypical antipsychotics: a case-control study
Jørgensen, Anders, Knorr, Ulla Benedichte Søsted, Soendergaard, M. G., Lykkesfeldt, Jens, Fink-Jensen, Anders, Poulsen, Henrik Enghusen, Jørgensen, Martin Balslev, Olsen, N. V. & Staalsø, J. M., 2015, In: B M C Psychiatry. 15, 8 p., 67.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Controlled exposure to particulate matter from urban street air is associated with decreased vasodilation and heart rate variability in overweight and older adults
Hemmingsen, J. G., Rissler, J., Lykkesfeldt, Jens, Sallsten, G., Kristiansen, J., Møller, Peter & Loft, Steffen, 2015, In: Particle and Fibre Toxicology. 12, 10 p., 6.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distribution of vitamin C is tissue specific with early saturation of the brain and adrenal glands following differential oral dose regimens in guinea pigs
Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2015, In: British Journal of Nutrition. 113, 10, p. 1539-1549 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elimination of ascorbic acid after high-dose infusion in prostate cancer patients: a pharmacokinetic evaluation
Nielsen, Torben Kjær, Højgaard, M., Andersen, J. T. T., Poulsen, Henrik Enghusen, Lykkesfeldt, Jens & Mikines, K. J., 2015, In: Basic & Clinical Pharmacology & Toxicology. 116, 4, p. 343-348 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Göttingen minipig model of diet-induced atherosclerosis: influence of mild streptozotocin-induced diabetes on lesion severity and markers of inflammation evaluated in obese, obese and diabetic, and lean control animals
Ludvigsen, Trine Pagh, Kirk, R. K., Christoffersen, B. Ø., Pedersen, H. D., Martinussen, Torben, Kildegaard, J., Heegaard, P. M. H., Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2015, In: Journal of Translational Medicine. 13, 12 p., 312.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal vitamin C deficiency during pregnancy results in transient fetal and placental growth retardation in guinea pigs: [Plus] erratum
Schjoldager, J. G., Paidi, M. D., Lindblad, M. M., Birck, M. M., Kjærgaard, A. B., Dantzer, V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2015, In: European Journal of Nutrition. 54, 4, p. 667-676 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Positive charge, negative effect: the impact of cationic nanoparticles in the brain
Møller, Peter & Lykkesfeldt, Jens, Jul 2014, In: Nanomedicine. 9, 10, p. 1441-3 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Antioxidant supplementation for lung disease in cystic fibrosis
Ciofu, Oana & Lykkesfeldt, Jens, 2014, In: The Cochrane library. 2014, 8, 87 p., CD007020.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats
Knudsen, K. B., Northeved, H., Gjetting, T., Permin, A., Andresen, T. L., Wegener, K. M., Rye Lam, H. & Lykkesfeldt, Jens, 2014, In: Journal of Nanoparticle Research. 16, 1, 11 p., 2221.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biopterin status in dogs with myxomatous mitral valve disease is associated with disease severity and cardiovascular risk factors
Reimann, Maria Josefine, Häggström, J., Mortensen, A., Lykkesfeldt, Jens, Møller, J. E., Falk, B. T. & Olsen, Lisbeth Høier, 2014, In: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. 28, 5, p. 1520-1526 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chronic vitamin C deficiency promotes redox imbalance in the brain but does not alter sodium-dependent vitamin C transporter 2 expression
Paidi, M. D., Schjoldager, J. G., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Nutrients. 6, 5, p. 1809-1822 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential toxicological response to positively and negatively charged nanoparticles in the rat brain
Knudsen, K. B., Northeved, H., Ek, P. K., Permin, A., Andresen, T. L., Larsen, S., Wegener, K. M., Lam, H. R. & Lykkesfeldt, Jens, 2014, In: Nanotoxicology. 8, 7, p. 764-774 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does vitamin C deficiency affect cognitive development and function?
Hansen, S. N., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2014, In: Nutrients. 6, 9, p. 3818-3846 29 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does vitamin C deficiency promote fatty liver disease development?
Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2014, In: Nutrients. 6, 12, p. 5473-5499 27 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies
Mortensen, A. & Lykkesfeldt, Jens, 2014, In: Nitric Oxide: Biology and Chemistry. 36, p. 51-57 7 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Effect of insulin-induced hypoglycaemia on the central nervous system: evidence from experimental studies
Jensen, Vivi Flou Hjorth, Bøgh, I. B. & Lykkesfeldt, Jens, 2014, In: Journal of Neuroendocrinology. 26, 3, p. 123-150 28 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of insulin-induced hypoglycaemia on the peripheral nervous system: focus on adaptive mechanisms, pathogenesis and histopathological changes
Jensen, Vivi Flou Hjorth, Mølck, A., Bøgh, I. B. & Lykkesfeldt, Jens, 2014, In: Journal of Neuroendocrinology. 26, 8, p. 482-496 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of melatonin on human nighttime endotoxaemia: randomized, double-blinded, cross-over study
Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 2014, In: In Vivo. 28, 6, p. 1057-1063 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4231856
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Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats
Research output: Contribution to journal › Journal article › Research › peer-review
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Increased systemic oxidatively generated DNA and RNA damage in schizophrenia
Research output: Contribution to journal › Journal article › Research › peer-review
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4595
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Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies
Research output: Contribution to journal › Review › Research › peer-review
Published