Jens Lykkesfeldt
Professor
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(R)-alfa-lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate
Hagen, T. M., Ingersoll, R. T., Lykkesfeldt, Jens, Liu, J., Wehr, C. M., Vinarsky, V., Bartholomew, J. C. & Ames, B. N., 1999, In: The FASEB Journal. 13, p. 411-4418 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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(R)-α-Lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate
Hagen, T. M., Ingersoll, R. T., Lykkesfeldt, Jens, Liu, J., Wehr, C. M., Vinarsky, V., Bartholomew, J. C. & Ames, B. N., 16 Feb 1999, In: FASEB Journal. 13, 2, p. 411-418 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2-Nitro-3-(p-hydroxyphenyl)propionate and aci-1-nitro-2-(p-hydroxyphenyl)ethane, two intermediates in the biosynthesis of the cyanogenic glucoside dhurrin in Sorghum bicolor (L.) Moench
Halkier, Barbara Ann, Lykkesfeldt, Jens & Møller, Birger Lindberg, 1 Jan 1991, In: Proceedings of the National Academy of Sciences of the United States of America. 88, 2, p. 487-491 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro toxicity of cationic micelles and liposomes in cultured human hepatocyte (HepG2) and lung epithelial (A549) cell lines
Roursgaard, Martin, Knudsen, K. B., Northeved, H., Persson, M., Christensen, T., Kumar, P. E. K., Permin, A., Andresen, T. L., Gjetting, T., Lykkesfeldt, Jens, Vesterdal, L. K., Loft, Steffen & Møller, Peter, Oct 2016, In: Toxicology in Vitro. 36, p. 164-171 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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L-dehydroascorbic acid can substitute L-ascorbic acid as dietary vitamin C source in guinea pigs
Frikke-Schmidt, H. R., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2016, In: Redox Biology. 7, p. 8-13 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A long‐term energy‐rich diet increases prefrontal bdnf in sprague‐dawley rats
Virtuoso, Alessandro, Tveden-Nyborg, Pernille, Schou‐pedersen, A. M. V., Lykkesfeldt, Jens, Müller, H. K., Elfving, B. & Sørensen, Dorte Bratbo, 2022, In: Nutrients. 14, 1, 126.Research output: Contribution to journal › Journal article › Research › peer-review
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A role of peroxisome proliferator-activated receptor gamma in non-alcoholic fatty liver disease
Skat-Rørdam, Josephine, Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, May 2019, In: Basic & Clinical Pharmacology & Toxicology. 124, 5, p. 528-537Research output: Contribution to journal › Review › Research › peer-review
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A sensitive venous bleeding model in haemophilia A mice: effects of two recombinant FVIII products (N8 and Advate®)
Pastoft, A. E., Lykkesfeldt, Jens, Ezban, M., Tranholm, M., Whinna, H. C. & Lauritzen, B., 2012, In: Haemophilia. 18, 5, p. 782-788 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A systematic Cochrane Review of antioxidant supplementation lung disease for cystic fibrosis
Ciofu, Oana, Smith, S. & Lykkesfeldt, Jens, 2020, In: Paediatric Respiratory Reviews. 33, p. 28-29Research output: Contribution to journal › Comment/debate › Research › peer-review
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Accelerated atherosclerosis caused by serum amyloid A response in lungs of ApoE−/− mice
Christophersen, D. V., Møller, Peter, Thomsen, Morten Bækgaard, Lykkesfeldt, Jens, Loft, Steffen, Wallin, H., Vogel, U. & Jacobsen, N. R., 2021, In: FASEB Journal. 35, 3, 14 p., e21307.Research output: Contribution to journal › Journal article › Research › peer-review
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Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity
Hagen, T. M., Ingersoll, R. T., Wehr, C. M., Lykkesfeldt, Jens, Vinarsky, V., Bartholomew, J. C., Song, M. & Ames, B. N., 1998, In: Proceedings of the National Academy of Science of the United States of America. 95, p. 9562-9566 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Age-associated decline in ascorbic acid concentration, recycling, and biosynthesis in rat hepatocytes: reversal with (R)-alfa-lipoic acid supplementation
Lykkesfeldt, Jens, Hagen, T. M., Vinarsky, V. & Ames, B. N., 1998, In: The FASEB Journal. 12, p. 1183-1189 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Age-dependent change in Vitamin C status: a phenomenon of matruration rather than of ageing
Lykkesfeldt, Jens & Moos, T., 2005, In: Mechanisms of Ageing and Development. 126, 8, p. 892-898 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ampicillin-improved glucose tolerance in diet-induced obese C57BL/6NTac mice is age dependent
Rune, Ida, Hansen, Camilla Hartmann Friis, Ellekilde, M., Nielsen, Dennis Sandris, Skovgaard, K., Rolin, B. C., Lykkesfeldt, Jens, Josefsen, K., Christensen, B. T., Kihl, Pernille & Hansen, Axel Kornerup, 2013, In: Experimental Diabetes Research. 2013, 13 p., 319321.Research output: Contribution to journal › Journal article › Research › peer-review
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An ELISA for detection of complement-bound circulating immune complexes in mice
Boysen, L., Lauritzen, B., Viuff, B. M., Lykkesfeldt, Jens & Landsy, L. H., 2019, In: Journal of Immunotoxicology. 16, 1, p. 82-86 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Animal Models of Fibrosis in Nonalcoholic Steatohepatitis: Do They Reflect Human Disease?
Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2020, In: Advances in Nutrition. 11, 6, p. 1696–1711Research output: Contribution to journal › Review › Research › peer-review
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Animal models in pharmacology and toxicology
Meyer, O. A., Svendsen, O. & Lykkesfeldt, Jens, 2011, Handbook of laboratory animal science: volume II: Animal models. Hau, J. & J. Schapiro, S. (eds.). 3. ed. ed. CRC Press, Vol. 2. p. 149-184 36 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Antioxidant supplementation does not alter endurance training adaptation
Yfanti, C., Åkerström, T., Nielsen, S., Nielsen, A. R., Mounier, R., Mortensen, Ole Hartvig, Lykkesfeldt, Jens, Rose, A. J., Fischer, C. P. & Pedersen, Bente Klarlund, 1 Jul 2010, In: Medicine and Science in Sports and Exercise. 42, 7, p. 1388-95 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antioxidant supplementation for lung disease in cystic fibrosis
Ciofu, Oana & Lykkesfeldt, Jens, 2014, In: The Cochrane library. 2014, 8, 87 p., CD007020.Research output: Contribution to journal › Journal article › Research › peer-review
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Antioxidant supplementation for lung disease in cystic fibrosis
Ciofu, Oana, Smith, S. & Lykkesfeldt, Jens, 2019, In: Cochrane Database of Systematic Reviews. 2019, 10, CD007020.Research output: Contribution to journal › Review › Research › peer-review
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Artemisinin induces omeprazole metabolism in human beings
Svensson, U. S. H., Ashton, M., Hai, T. N., Bertilsson, L., Huong, D. X., Van Huong, N., Niêu, N. T., Sy, N. D., Lykkesfeldt, Jens & Công, L. D., 1 Aug 1998, In: Clinical Pharmacology and Therapeutics. 64, 2, p. 160-167 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbate and dehydroascorbic acid as biomarkers of oxidative stress: validity of clinical data depends on vacutainer system used
Lykkesfeldt, Jens, 2012, In: Nutrition Research. 32, 1, p. 66-69 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbate and dehydroascorbic acid as reliable biomarkers of oxidative stress: analytical reproducibility and long-term stability of plasma samples subjected to acidic deproteinization
Lykkesfeldt, Jens, 2007, In: Cancer Epidemiology, Biomarkers & Prevention. 16, 11, p. 2513-2516 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbate deficiency increases progression of shigellosis in guinea pigs and mice infection models
Skerniskyte, J., Mulet, C., André, A. C., Anderson, M. C., Injarabian, L., Buck, A., Prade, V. M., Sansonetti, P. J., Reibel-Foisset, S., Walch, A. K., Lebel, M., Lykkesfeldt, Jens & Marteyn, B. S., 2023, In: Gut Microbes. 15, 2, 18 p., 2271597.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbate is depleted by smoking and repleted by moderate supplementation: a study in male smokers and nonsmokers with matched dietary antioxidant intakes
Lykkesfeldt, Jens, Christen, S., Wallock, L. M., Chang, H. H., Jacob, R. A. & Ames, B. N., 2000, In: American Journal of Clinical Nutrition. 71, p. 530-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbate maintains a low plasma oxygen level
Injarabian, L., Scherlinger, M., Devin, A., Ransac, S., Lykkesfeldt, Jens & Marteyn, B. S., 2020, In: Scientific Reports. 10, 1, 6 p., 10659.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbate status modulates reticuloendothelial iron stores and response to deferasirox iron chelation in ascorbate-deficient rats
Brewer, C., Otto-Duessel, M., Lykkesfeldt, Jens, Nick, H. & Wood, J. C., 2012, In: Experimental Hematology. 40, 10, p. 820-827 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbic acid and dehydroascorbic acid as biomarkers of oxidative stress caused by smoking, 1-3
Lykkesfeldt, Jens, Loft, Steffen, Nielsen, J. B. & Poulsen, Henrik Enghusen, 1997, In: American Journal of Clinical Nutrition. 65, p. 959-963Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbic acid recycling in human erythrocytes is induced by smoking in vivo
Lykkesfeldt, Jens, Viscovich, M. & Poulsen, H. E., 2003, In: Free Radical Biology & Medicine. 11, 11, p. 1439-1447 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbic acid recycling in rat hepatocytes as measurement of antioxidant capacity: decline with age
Lykkesfeldt, Jens & Ames, B. N., 1999, In: Methods in Enzymology. 299, p. 83-88 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbic acid recycling in rat hepatocytes as measurement of antioxidant capacity: Decline with age
Lykkesfeldt, Jens & Ames, B. N., 3 Nov 1998, In: Methods in Enzymology. 299, p. 83-88 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ascorbic acid recycling in rat hepatocytes as measurement of antioxidant capacity: decline with age
Lykkesfeldt, Jens & Ames, B. N., 1999, Oxidants and antioxidants part A. Packer, L. (ed.). San Diego: Academic Press, Vol. 299. p. 83-88 6 p. (Methods in Enzymology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Assessment of implantable infusion pumps for continuous infusion of human insulin in rats: potential for group housing
Jensen, Vivi Flou Hjorth, Molck, A., Martensson, M., Strid, M. A., Chapman, M., Lykkesfeldt, Jens & Bogh, I. B., 2017, In: Laboratory Animals. 51, 3, p. 273-283Research output: Contribution to journal › Journal article › Research › peer-review
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Asymmetric dimethylarginine in somatically healthy schizophrenia patients treated with atypical antipsychotics: a case-control study
Jørgensen, Anders, Knorr, Ulla Benedichte Søsted, Soendergaard, M. G., Lykkesfeldt, Jens, Fink-Jensen, Anders, Poulsen, Henrik Enghusen, Jørgensen, Martin Balslev, Olsen, N. V. & Staalsø, J. M., 2015, In: B M C Psychiatry. 15, 8 p., 67.Research output: Contribution to journal › Journal article › Research › peer-review
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Atorvastatin and vitamin e accelerates NASH resolution by dietary intervention in a preclinical guinea pig model
Klaebel, J. H., Skjødt, M., Skat-Rørdam, Josephine, Rakipovski, G., Ipsen, David Højland, Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Nutrients. 11, 11, 20 p., 2834.Research output: Contribution to journal › Journal article › Research › peer-review
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BCPT 2023 policy for experimental and clinical studies
Tveden-Nyborg, Pernille, Bergmann, T. K., Jessen, N., Simonsen, U. & Lykkesfeldt, Jens, 2023, In: Basic and Clinical Pharmacology and Toxicology. 133, 4, p. 391-396Research output: Contribution to journal › Journal article › Research › peer-review
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BCPT policy for experimental and clinical studies
Tveden-Nyborg, Pernille, Bergmann, T. K., Jessen, N., Simonsen, U. & Lykkesfeldt, Jens, 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 1, p. 4-8Research output: Contribution to journal › Review › Research › peer-review
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Basic & Clinical Pharmacology & Toxicology Policy for Experimental and Clinical studies
Tveden-Nyborg, Pernille, Bergmann, T. K. & Lykkesfeldt, Jens, 2018, In: Basic & Clinical Pharmacology & Toxicology. 123, 3, p. 233-235 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Biochemical and cognitive effects of docosahexaenoic acid differ in a developmental and SorLA dependent manner
Højland, A., Richner, M., Mølgaard, S., Dieu, R. S., Eskelund, A., Nykjær, A., Nyengaard, J. R., Lykkesfeldt, Jens, Glerup, S. & Nielsen, M. S., 2018, In: Behavioural Brain Research. 348, p. 90-100 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biochemical markers as indicators of the efficiency of antibiotic treatment of Actinobacillus pleuropneumoniae infection in pigs
Lauritsen, B., Lykkesfeldt, Jens, Angen, Ø. & Friis, C., 2000. 1 p.Research output: Contribution to conference › Paper › Research
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Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats
Knudsen, K. B., Northeved, H., Gjetting, T., Permin, A., Andresen, T. L., Wegener, K. M., Rye Lam, H. & Lykkesfeldt, Jens, 2014, In: Journal of Nanoparticle Research. 16, 1, 11 p., 2221.Research output: Contribution to journal › Journal article › Research › peer-review
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Biomarkers in evaluation of antibiotic treatment: an experimental model of porcine Actinobacillus pleuropneumoniae infection
Lauritzen, B., Lykkesfeldt, Jens, Angen, Ø., Nielsen, Jens Peter & Friis, C., 2002.Research output: Contribution to conference › Paper › Research
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Biopterin status in dogs with myxomatous mitral valve disease is associated with disease severity and cardiovascular risk factors
Reimann, Maria Josefine, Häggström, J., Mortensen, A., Lykkesfeldt, Jens, Møller, J. E., Falk, B. T. & Olsen, Lisbeth Høier, 2014, In: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. 28, 5, p. 1520-1526 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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C-Vitamin mod åreforkalkning
Frikke-Schmidt, H. R. & Lykkesfeldt, Jens, 2009, In: Aktuel Naturvidenskab. 3, p. 26-29 4 p.Research output: Contribution to journal › Journal article › Communication
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Cardiovascular health effects of oral and pulmonary exposure to multi-walled carbon nanotubes in ApoE-deficient mice
Christophersen, D. V., Raun Jacobsen, N., Guerra Andersen, M. H., Connell, S. P., Barfod, K. K., Thomsen, Morten Bækgaard, Miller, M. R., Duffin, R., Lykkesfeldt, Jens, Vogel, U. B., Wallin, E. H. R., Loft, Steffen, Roursgaard, Martin & Møller, Peter, 14 Sep 2016, In: Toxicology. 371, p. 29-40 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Carotid Artery Intima-Media Thickness and Cutaneous Microvascular Function are Associated With Vitamin C Levels in Young Patients With Type 1 Diabetes
Odermarsky, M., Lykkesfeldt, Jens & Liuba, P., 2008, Scientific Sessions 2008.Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research
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Cerebral vasculature is the major target of oxidative protein alterations in bacterial meningitis
Schaper, M., Gergely, S., Lykkesfeldt, Jens, Zbären, J., Leib, S. L., Täuber, M. G. & Christen, S., 2002, In: Journal of Neuropathology and Experimental Neurology. 61, 7, p. 605-613 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Charting a new course: A vision for the future as editors-in-chief
Simonsen, U. & Lykkesfeldt, Jens, 2023, In: Basic and Clinical Pharmacology and Toxicology. 133, 4, p. 390 1 p.Research output: Contribution to journal › Editorial › Research
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Chronic Hyperinsulinaemic Hypoglycaemia in Rats Is Accompanied by Increased Body Weight, Hyperleptinaemia, and Decreased Neuronal Glucose Transporter Levels in the Brain
Jensen, Vivi Flou Hjorth, Molck, A., Chapman, M., Alifrangis, L., Andersen, L., Lykkesfeldt, Jens & Bogh, I. B., 2017, In: International Journal of Endocrinology. 2017, 14 p., 7861236.Research output: Contribution to journal › Journal article › Research › peer-review
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Chronic dyslipidemia induces fatty liver disease in Guinea pigs
Tveden-Nyborg, Pernille, Birck, M. M., Ipsen, David Højland & Lykkesfeldt, Jens, Jul 2015, In: Atherosclerosis. 241, 1, p. e119-e120 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
ID: 4231856
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Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats
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Increased systemic oxidatively generated DNA and RNA damage in schizophrenia
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Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies
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