Jakob Benedict Seidelin

Jakob Benedict Seidelin

Clinical Professor

Member of:

  • Internal Medicine: Gastroenterology and Hepatology

ORCID: 0000-0003-3230-7966

Publication year:
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1 - 100 out of 116Page size: 100
  1. 2024
  2. E-pub ahead of print

    Predicting treatment response in ASUC: do we measure systemic severity, organ response or both?

    Ovesen, P. D., Ilvemark, J. F. K. F., Wilkens, R., Steenholdt, Casper & Seidelin, Jakob Benedict, 1 Apr 2024, (E-pub ahead of print) In: Gut. 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  3. Published

    Intestinal ultrasound in inflammatory bowel disease

    Bjerrum, Jakob Tveiten , Ilvemark, J., Seidelin, Jakob Benedict & Wilkens, R., 5 Feb 2024, In: Ugeskrift for Laeger. 186, 6

    Research output: Contribution to journal › Review › Research › peer-review

  4. Published

    Editorial: Time to address quality of life in our IBD treatment — IBD nurse intervention as a key part of multimodal IBD management

    Seidelin, Jakob Benedict, 2024, In: Alimentary Pharmacology and Therapeutics. 59, 9, p. 1152-1153

    Research output: Contribution to journal › Editorial › Research › peer-review

  5. Published

    IAPs and RIPK1 mediate LPS-induced cytokine production in healthy subjects and Crohn's disease

    Seidelin, Jakob Benedict, Jensen, Simone, Hansen, M., Bronze, M. R. D. C., Cuchet-Lourenҫo, D., Nejentsev, S., LaCasse, E. C. & Nielsen, Ole Haagen, 2024, In: Clinical and Experimental Immunology. 215, 3, p. 291–301 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Accepted/In press

    Infant Ustekinumab Clearance, Risk of Infection, and Development After Exposure During Pregnancy

    Julsgaard, M., Wieringa, J. W., Baunwall, S. M. D., Bibby, B. M., Driessen, G. J. A., Kievit, L., Brodersen, J. B., Poulsen, A., Kjeldsen, J., Hansen, M. M., Tang, H. Q., Balmer, C. L., Glerup, H., Seidelin, J. B., Haderslev, K. V., Svenningsen, L., Wildt, S., Juel, M. A., Neumann, A., Fuglsang, J. & 31 others, Jess, T., Haase, A. M., Hvas, C. L., Kelsen, J., Janneke van der Woude, C., Korgaard, J., Vestergaard, T., Lystbæk, U. L., Berg, A., Mikkelsen, A. T., Holm, A. M., Hansen, A. B., Mathiesen, O., Jensen, J. K., Neumann, L., Boris, J., Lemming, M., Rahbek, M., Westergaard, H. B., Friis-Hansen, L. J., Møller, L. A., Søeby, K., Hilsted, L., Christiansen, L., Sharif, H., Langholz, Ebbe, Kamstrup, P. R., Jochumsen, A., Huusom, Lene Drasbek, Wilken-Jensen, C. & NEXUS Collaborator Group, N. C. G., 2024, (Accepted/In press) In: Clinical Gastroenterology and Hepatology. 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. E-pub ahead of print

    Peripheral joint and enthesis involvement in patients with newly diagnosed inflammatory bowel disease: symptoms, clinical and ultrasound findings - a population-based cohort study

    Vladimirova, N., Terslev, Lene, Attauabi, M., Madsen, G., Fana, V., Wiell, C., Døhn, U. M., Bendtsen, Flemming, Seidelin, Jakob Benedict, Burisch, J. & Østergaard, Mikkel, 2024, (E-pub ahead of print) In: Journal of Crohn's & colitis.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 2023
  9. Published

    Editorial: safety and efficacy of infliximab and corticosteroids in checkpoint inhibitor-induced colitis—authors' reply

    Dahl, E. K., Abed, O. K., Kjeldsen, J., dqp123, dqp123, Svane, Inge Marie, Dige, A., Agnholt, J. S., Bjerrum, Jakob Tveiten & Seidelin, Jakob Benedict, Jan 2023, In: Alimentary Pharmacology and Therapeutics. 57, 1, p. 152-153 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  10. Published

    Comparative onset of effect of biologics and small molecules in moderate-to-severe ulcerative colitis: a systematic review and network meta-analysis

    Attauabi, M., Dahl, E. K., Burisch, J., Gubatan, J., Nielsen, Ole Haagen & Seidelin, Jakob Benedict, 2023, In: EClinicalMedicine. 57, 3, 101866.

    Research output: Contribution to journal › Review › Research › peer-review

  11. Published

    Disease Activity Patterns of Inflammatory Bowel Disease - A Danish Nationwide Cohort Study 1995-2018

    Wewer, M. D., Langholz, Ebbe, Munkholm, Pia, Bendtsen, Flemming, Seidelin, Jakob Benedict & Burisch, J., 2023, In: Journal of Crohn's & colitis. 17, 3, p. 329–337

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Distinct immune cell trigger responses in Ulcerative Colitis – Results from an in vivo human intestinal injury model

    Bronze, M., Johansen, Jens Vilstrup, Attauabi, M., Bjerrum, Jakob Tveiten , Ramírez Galera, Marina, Woetmann, Anders & Seidelin, Jakob Benedict, 2023, In: Journal of Crohn's and Colitis. 17, Supplement_1, p. i199-i200

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  13. Published

    Letter: be careful of gastrointestinal CMV infection in adverse event from ICIs therapy in solid tumours — Authors' reply

    Dahl, E., Abed, O., Agnholt, J., Bjerrum, Jakob Tveiten , Dige, A., Kjeldsen, J., Svane, Inge Marie, Donia, M. & Seidelin, Jakob Benedict, 2023, In: Alimentary Pharmacology and Therapeutics. 57, 8, p. 918-919

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  14. Published

    Optimizing Screening for Colorectal Cancer: An Algorithm Combining Fecal Immunochemical Test, Blood-Based Cancer-Associated Proteins and Demographics to Reduce Colonoscopy Burden

    Petersen, M. M., Kleif, Jakob, Jørgensen, Lars Nannestad, Hendel, J. W., Seidelin, Jakob Benedict, Madsen, M. R., Vilandt, J., Brandsborg, S., Rasmussen, J. S., Andersen, L. M., Khalid, A., Ferm, L., Gawel, S. H., Martens, F., Andersen, B., Rasmussen, Morten, Davis, G. J., Christensen, I. J. & Therkildsen, C., 2023, In: Clinical Colorectal Cancer. 22, 2, p. 199-210 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Reply to comment on: "Vedolizumab as the first line of biologic therapy for ulcerative colitis and Crohn's disease - a systematic review with meta-analysis"

    Attauabi, M., Seidelin, Jakob Benedict & Burisch, J., 2023, In: Rendiconti di Gastro-Enterologia. 55, 2, p. 300-301

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  16. Published

    Systematic Review with Meta-analysis: The Impact of Cancer Treatments on the Disease Activity of Inflammatory Bowel Diseases

    Grimsdottir, S., Attauabi, M., Kristine Dahl, E., Burisch, J. & Seidelin, Jakob Benedict, 2023, In: Journal of Crohn's and Colitis. 17, 7, p. 1139-1153 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  17. Published

    Tofacitinib for acute severe ulcerative colitis: a systematic review

    Steenholdt, Casper, Ovesen, P. D., Brynskov, J. & Seidelin, Jakob Benedict, 2023, In: Journal of Crohn's and Colitis. 17, 8, p. 1354-1363

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    Unraveling the Place of Small Molecules in theTreatment of Fistulizing Crohn’s Disease—A Systematic Review and Network Meta-Analysis

    Attauabi, M., Rasmussen, D. N., Bergenheim, F. O., Burisch, J. & Seidelin, Jakob Benedict, 2023, In: Crohn's and Colitis 360. 5, 4, 2 p., otad074.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  19. 2022
  20. Published

    Association Between the Clinical, Biochemical, and Endoscopic Activity of Inflammatory Bowel Diseases and Severity and Long-term Outcomes of Coronavirus Disease 2019 - A Population-based Study

    Attauabi, M., Dahlerup, J. F., Poulsen, A., Hansen, M. R., Vester-Andersen, Marianne Kajbæk, Prahm, A. P., Pedersen, N., Larsen, L., Jess, T., Neumann, A., Haderslev, K. V., Molazahi, A., Lødrup, A. B., Glerup, H., Oppfeldt, A. M., Jensen, M. D., Theede, K., Kiszka-Kanowitz, M., Seidelin, Jakob Benedict & Burisch, J., 2022, In: Inflammatory Bowel Diseases. 28, 10, p. 1618-1622

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Defining transabdominal Intestinal Ultrasound treatment response and remission in Inflammatory Bowel Disease: Systematic review and expert consensus statement

    Ilvemark, J. F. K. F., Hansen, T., Goodsall, T. M., Seidelin, J. B., Al-Farhan, H., Allocca, M., Begun, J., Bryant, R. V., Carter, D., Christensen, B., Dubinsky, M. C., Gecse, K. B., Kucharzik, T., Lu, C., Maaser, C., Maconi, G., Nylund, K., Palmela, C., Wilson, S. R., Novak, K. & 1 others, Wilkens, R., 2022, In: Journal of Crohn's and Colitis. 16, 4, p. 554–580

    Research output: Contribution to journal › Review › Research › peer-review

  22. Published

    Early intestinal ultrasound predicts intravenous corticosteroid response in hospitalized patients with severe ulcerative colitis

    Ilvemark, J. F. K. F., Wilkens, R., Thielsen, P., Dige, A., Boysen, T., Brynskov, J., Bjerrum, Jakob Tveiten & Seidelin, Jakob Benedict, 2022, In: Journal of Crohn's & colitis. 16, 11, p. 1725–1734

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Etrolizumab as induction and maintenance therapy for ulcerative colitis in patients previously treated with tumour necrosis factor inhibitors (HICKORY): a phase 3, randomised, controlled trial

    Peyrin-Biroulet, L., Hart, A., Bossuyt, P., Long, M., Allez, M., Juillerat, P., Armuzzi, A., Loftus, E. V., Ostad-Saffari, E., Scalori, A., Oh, Y. S., Tole, S., Chai, A., Pulley, J., Lacey, S., Sandborn, W. J., Aguilar, H., Ahmad, T., Akriviadis, E., Aldeguer Mante, X. & 31 others, Altorjay, I., Ananthakrishnan, A., Andersen, V., Andreu Garcia, M., Aumais, G., Avni-Biron, I., Axler, J., Ayub, K., Baert, F., Bafutto, M., Bamias, G., Bassan, I., Baum, C., Beaugerie, L., Behm, B., Bekal, P., Bennett, M., Bermejo San Jose, F., Bernstein, C., Bettenworth, D., Bhaskar, S., Biancone, L., Bilir, B., Blaeker, M., Bloom, S., Bohman, V., Bosques Padilla, F. J., Bouhnik, Y., Seidelin, Jakob Benedict, Staun, Michael & HICKORY Study Group, H. S. G., 2022, In: The Lancet Gastroenterology and Hepatology. 7, 2, p. 128-140 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Etrolizumab for maintenance therapy in patients with moderately to severely active ulcerative colitis (LAUREL): a randomised, placebo-controlled, double-blind, phase 3 study

    Vermeire, S. & LAUREL Study Group, L. S. G., 2022, In: The Lancet Gastroenterology and Hepatology. 7, 1, p. 28-37 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Inflammatory Bowel Diseases Affect the Phenotype and Disease Course of Coexisting Immune-Mediated Inflammatory Diseases: A Systematic Review With Meta-Analysis

    Attauabi, M., Wewer, M. D., Bendtsen, Flemming, Seidelin, Jakob Benedict & Burisch, J., 2022, In: Inflammatory Bowel Diseases. 28, 11, p. 1756–1765

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Influence of Genetics, Immunity and the Microbiome on the Prognosis of Inflammatory Bowel Disease (IBD Prognosis Study): the protocol for a Copenhagen IBD Inception Cohort Study

    Attauabi, M., Madsen, G. R., Bendtsen, F., Wewer, A. V., Wilkens, R., Ilvemark, J., Vladimirova, N., Jensen, A. B., Jensen, F. K., Hansen, S. B., Siebner, H. R., Nielsen, Y. J. W., Møller, J. M., Thomsen, H. S., Thomsen, S. F., Ingels, H. A. S., Theede, K., Boysen, T., Bjerrum, J. T., Jakobsen, C. & 13 others, Dorn-Rasmussen, M., Jansson, S., Yao, Y., Burian, E. A., Møller, F. T., Fana, V., Wiell, C., Terslev, Lene, Østergaard, Mikkel, Bertl, K., Stavropoulos, A., Seidelin, Jakob Benedict & Burisch, J., 2022, In: BMJ Open. 12, 6, e055779.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Lipidomic Trajectories Characterize Delayed Mucosal Wound Healing in Quiescent Ulcerative Colitis and Identify Potential Novel Therapeutic Targets

    Bjerrum, Jakob Tveiten , Wang, Y., Zhang, J., Riis, Lene Buhl, Nielsen, Ole Haagen & Seidelin, Jakob Benedict, 2022, In: International Journal of Biological Sciences. 18, 5, p. 1813-1828 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Outcomes and long-term effects of COVID-19 in patients with inflammatory bowel diseases - a Danish prospective population-based cohort study with individual-level data

    Attauabi, M., Dahlerup, J. F., Poulsen, A., Hansen, M. R., Verner-Andersen, M. K., Eraslan, S., Prahm, A. P., Pedersen, N., Larsen, L., Jess, T., Neumann, A., Haderslev, K. V., Molazahi, A., Lødrup, A. B., Glerup, H., Oppfeldt, A. M., Jensen, M. D., Theede, K., Kiszka-Kanowitz, M., Seidelin, J. B. & 1 others, Burisch, J., 2022, In: Journal of Crohn's and Colitis. 16, 5, p. 757–767 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Praktisk anvendelse af thiopuriner hos patienter med kronisk inflammatoriske tarmsygdomme

    Zhao, M., Wewer, M. D., Bjerrum, Jakob Tveiten , Steenholdt, Casper, Schiødt, Frank Vinholt, Haderslev, K., Kiszka-Kanowitz, M., Munkholm, Pia, Seidelin, Jakob Benedict & Burisch, J., 2022, In: Ugeskrift for Laeger. 184, 11, V09210706.

    Research output: Contribution to journal › Review › Research › peer-review

  30. Published

    Prediction of Relapse After Anti–Tumor Necrosis Factor Cessation in Crohn's Disease: Individual Participant Data Meta-analysis of 1317 Patients From 14 Studies

    Pauwels, R. W. M., van der Woude, C. J., Nieboer, D., Steyerberg, E. W., Casanova, M. J., Gisbert, J. P., Kennedy, N. A., Lees, C. W., Louis, E., Molnár, T., Szántó, K., Leo, E., Bots, S., Downey, R., Lukas, M., Lin, W. C., Amiot, A., Lu, C., Roblin, X., Farkas, K. & 15 others, Seidelin, Jakob Benedict, Duijvestein, M., D'Haens, G. R., de Vries, A. C., Janneke van der Woude, C., Sleutjes, J. A. M., García-Ortiz, J. M., Brooks, A. J., Hamlin, P. J., Sebastian, S., Lobo, A. J., Dieleman, L. (. A., Ben-Horin, S., Steenholdt, Casper & CEASE Study Group, C. S. G., 2022, In: Clinical Gastroenterology and Hepatology. 20, 8, p. 1671-1686.e16

    Research output: Contribution to journal › Review › Research › peer-review

  31. Published

    Safety and efficacy of infliximab and corticosteroid therapy in checkpoint inhibitor-induced colitis

    Dahl, E. K., Abed, O. K., Kjeldsen, J., dqp123, dqp123, Svane, Inge Marie, Dige, A., Agnholt, J. S., Bjerrum, Jakob Tveiten & Seidelin, Jakob Benedict, 2022, In: Alimentary Pharmacology and Therapeutics. 56, 9, p. 1370-1382 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    The effect of induced hyperammonaemia on sleep and melanopsin-mediated pupillary light response in patients with liver cirrhosis: A single-blinded randomized crossover trial

    Kann, A. E., Ba-Ali, S., Seidelin, Jakob Benedict, Larsen, F. S., Hamann, Steffen & Bjerring, Peter Nissen, 2022, In: PLoS ONE. 17, 9 , e0275067.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Tofacitinib and faecal microbiota transplantation in treating checkpoint inhibitor-induced enterocolitis: case report

    Holmstroem, R. B., Dahl, E. K., Helms, Morten, Nielsen, H. V., Andersen, J. B., Bjerrum, Jakob Tveiten , Svane, Inge Marie, Ellebaek, E. & Seidelin, Jakob Benedict, 2022, In: BMJ Open Gastroenterology. 9, 1, 4 p., e000989.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Ulcerative Colitis and Acute Severe Ulcerative Colitis Patients Are Overlooked in Infliximab Population Pharmacokinetic Models: Results from a Comprehensive Review

    Démaris, A., Widigson, E. S. K., Ilvemark, J. F. K. F., Steenholdt, Casper, Seidelin, Jakob Benedict, Huisinga, W., Michelet, R., Aulin, L. B. S. & Kloft, C., 2022, In: Pharmaceutics. 14, 10, 2095.

    Research output: Contribution to journal › Review › Research › peer-review

  35. Published

    Vedolizumab as the first line of biologic therapy for ulcerative colitis and Crohn's disease – a systematic review with meta-analysis

    Attauabi, M., Madsen, G. R., Bendtsen, Flemming, Seidelin, Jakob Benedict & Burisch, J., 2022, In: Digestive and Liver Disease. 54, 9, p. 1168-1178

    Research output: Contribution to journal › Review › Research › peer-review

  36. 2021
  37. Published

    Authors' Reply to: 'COVID-19 in the IBD Population: The Need for Correct Nomenclature'

    Attauabi, M., Seidelin, Jakob Benedict & Burisch, J., 22 Jun 2021, In: Journal of Crohn's & colitis. 15, 6, p. 1080 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  38. Published

    Coronavirus disease 2019, immune-mediated inflammatory diseases and immunosuppressive therapies – A Danish population-based cohort study

    Attauabi, M., Seidelin, Jakob Benedict, Felding, O. K., Wewer, M. D., Vinther Arp, L. K., Sarikaya, M. Z., Egeberg, A., Vladimirova, N., Bendtsen, Flemming & Burisch, J., Mar 2021, In: Journal of Autoimmunity. 118, 102613.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Acute Experimental Barrier Injury Triggers Ulcerative Colitis–Specific Innate Hyperresponsiveness and Ulcerative Colitis–Type Microbiome Changes in Humans

    Seidelin, Jakob Benedict, Bahl, M. I., Licht, T. R., Mead, B. E., Karp, J. M., Johansen, Jens Vilstrup, Riis, Lene Buhl, Ramírez Galera, Marina, Woetmann, Anders & Bjerrum, Jakob Tveiten , 2021, In: Cellular and Molecular Gastroenterology and Hepatology. 12, 4, p. 1281-1296

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Association between 5-aminosalicylates in patients with IBD and risk of severe COVID-19: an artefactual result of research methodology?

    Attauabi, M. & Danish COVID-IBD Study Group, D. C. S. G., 2021, In: Gut. 70, 10, p. 2020-2022

    Research output: Contribution to journal › Letter › Research › peer-review

  41. Published

    CDX2 regulates interleukin-33 gene expression in intestinal epithelial cells (LS174T)

    Larsen, S., Seidelin, Jakob Benedict, Davidsen, J., Dahlgaard, K., Nielsen, Claus Henrik, Bennett, Eric Paul, Pedersen, O. B., Coskun, M. & Troelsen, J. T., 2021, In: FEBS Open Bio. 11, 6, p. 1638-1644

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Effectiveness of third-class biologic treatment in crohn’s disease: A multi-center retrospective cohort study

    Albshesh, A., Taylor, J., Savarino, E. V., Truyens, M., Armuzzi, A., Ribaldone, D. G., Shitrit, A. B. G., Fibelman, M., Molander, P., Liefferinckx, C., Nancey, S., Korani, M., Rutka, M., Acosta, M. B. D., Domislovic, V., Suris, G., Eriksson, C., Alves, C., Mpitouli, A., Di Jiang, C. & 26 others, Tepeš, K., Coletta, M., Foteinogiannopoulou, K., Gisbert, J. P., Amir-Barak, H., Attauabi, M., Seidelin, Jakob Benedict, Afif, W., Marinelli, C., Lobaton, T., Pugliese, D., Maharshak, N., Cremer, A., Limdi, J. K., Molnár, T., Otero-Alvarin, B., Krznaric, Z., Magro, F., Karmiris, K., Raine, T., Drobne, D., Koutroubakis, I., Chaparro, M., Yanai, H., Burisch, J. & Kopylov, U., 2021, In: Journal of Clinical Medicine. 10, 13, 2914.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Efficacy of Ustekinumab for Active Perianal Fistulizing Crohn Disease: A Double-Center Cohort Study

    Attauabi, M., Burisch, J. & Seidelin, Jakob Benedict, 2021, In: Inflammatory Bowel Diseases. 27, 3, p. e37-e38

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  44. Published

    Efficacy of ustekinumab for active perianal fistulizing Crohn’s disease: a systematic review and meta-analysis of the current literature

    Attauabi, M., Burisch, J. & Seidelin, Jakob Benedict, 2021, In: Scandinavian Journal of Gastroenterology. 56, 1, p. 53-58 6 p.

    Research output: Contribution to journal › Review › Research › peer-review

  45. Published

    IBD metabonomics predicts phenotype, disease course, and treatment response

    Bjerrum, Jakob Tveiten , Wang, Y. L., Seidelin, Jakob Benedict & Nielsen, Ole Haagen, 2021, In: EBioMedicine. 71, 103551.

    Research output: Contribution to journal › Review › Research › peer-review

  46. Published

    Prevalence and outcomes of COVID-19 among patients with inflammatory bowel disease: A Danish prospective population-based cohort study

    Attauabi, M., Poulsen, A., Theede, K., Pedersen, N., Larsen, L., Jess, T., Rosager Hansen, M., Kajbæk Verner-Andersen, M., V Haderslev, K., Berg Lødrup, A., Molazahi, A., Neumann, A., Wase, A., Seidelin, Jakob Benedict & Burisch, J., 2021, In: Journal of Crohn's and Colitis. 15, 4, p. 540–550

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Short and long-term effectiveness and safety of vedolizumab in treatment-refractory patients with ulcerative colitis and Crohn's disease - a real-world two-center cohort study

    Attauabi, M., Vind, Ida, Pedersen, G., Bendtsen, Flemming, Seidelin, Jakob Benedict & Burisch, J., 2021, In: European journal of gastroenterology & hepatology. 33, 15, p. 709-718

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    The Incidence and Disease Course of Perianal Crohn's Disease: A Danish Nationwide Cohort Study, 1997-2015

    Wewer, M. D., Zhao, M., Nordholm-Carstensen, A., Weimers, P., Seidelin, Jakob Benedict & Burisch, J., 2021, In: Journal of Crohn's and Colitis (JCC). 15, 1, p. 5-13

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Vedolizumab as first-line biological therapy in elderly patients and those with contraindications for anti-TNF therapy: a real-world, nationwide cohort of patients with inflammatory bowel diseases

    Attauabi, M., Höglund, C., Fassov, J., Pedersen, K. B., Hansen, H. B., Wildt, S., Jensen, M. D., Neumann, A., Lind, C., Jacobsen, H. A., Popa, A. M., Kjeldsen, J., Pedersen, N., Molazahi, A., Haderslev, K., Aalykke, C., Knudsen, T., Cebula, W., Munkholm, P., Bendtsen, F. & 2 others, Seidelin, Jakob Benedict & Burisch, J., 2021, In: Scandinavian Journal of Gastroenterology. 56, 9, p. 1040-1048

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. 2020
  51. Published

    A fully defined 3D matrix for ex vivo expansion of human colonic organoids from biopsy tissue

    Bergenheim, F., Fregni, G., Buchanan, C. F., Riis, Lene Buhl, Heulot, M., Touati, J., Seidelin, Jakob Benedict, Rizzi, S. C. & Nielsen, Ole Haagen, 2020, In: Biomaterials. 262, 11 p., 120248.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Crohn's disease with progressive renal impairment

    Seidelin, Jakob Benedict, Riis, Lene Buhl & Butt, Rizwan Ahmed, 2020, In: Gastroenterology. 158, 1, p. 58-59 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  53. Published

    Predictors of response and disease course in patients with inflammatory bowel disease treated with biological therapy - The Danish IBD Biobank Project: protocol for a multicentre prospective cohort study

    Zhao, M., Bendtsen, Flemming, Petersen, Andreas Munk, Larsen, L., Dige, A., Hvas, C., Seidelin, Jakob Benedict & Burisch, J., 2020, In: BMJ Open. 10, 2, 7 p., e035756.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    SMAC mimetics and RIPK inhibitors as therapeutics for chronic inflammatory diseases

    Jensen, S., Seidelin, Jakob Benedict, LaCasse, E. C. & Nielsen, Ole Haagen, 2020, In: Science Signaling. 13, 619, 18 p., eaax8295.

    Research output: Contribution to journal › Review › Research › peer-review

  55. 2019
  56. Published

    Exposome and Diet

    Seidelin, Jakob Benedict & Burisch, J., 2019, Biomarkers in Inflammatory Bowel Diseases. Sheng Ding, N. & De Cruz, P. (eds.). Springer, p. 281-291 Chapter 23

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  57. Published

    Fluorescence-based tracing of transplanted intestinal epithelial cells using confocal laser endomicroscopy

    Bergenheim, F., Seidelin, Jakob Benedict, Pedersen, M. T., Mead, B. E., Jensen, Kim Bak, Karp, J. M. & Nielsen, Ole Haagen, 2019, In: Stem Cell Research & Therapy. 10, 1, p. 1-12 12 p., 148.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. 2018
  59. Published

    COX-2-PGE2 Signaling Impairs Intestinal Epithelial Regeneration and Associates with TNF Inhibitor Responsiveness in Ulcerative Colitis

    Li, Yuan, Soendergaard, C., Bergenheim, F. H., Aronoff, D. M., Milne, G., Riis, Lene Buhl, Seidelin, Jakob Benedict, Jensen, Kim Bak & Nielsen, Ole Haagen, 2018, In: EBioMedicine. 36, p. 497-507

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies

    Boyd, M., Thodberg, M., Vitezic, M., Lange, J. B., Vitting-Seerup, K., Chen, Y., Coskun, M., Li, Y., Lo, B. Z. S., Klausen, P., Schweiger, P., Pedersen, A. G., Rapin, N. P. J-P., Skovgaard, K., Dahlgaard, K., Andersson, R., Terkelsen, T. B., Lilje, B., Troelsen, J. T., Petersen, A. M. & 7 others, Jensen, Kim Bak, Gögenur, Ismail, Thielsen, P., Seidelin, Jakob Benedict, Nielsen, Ole Haagen, Bjerrum, Jakob Tveiten & Sandelin, Albin Gustav, 2018, In: Nature Communications. 9, 19 p., 1661.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Putative biomarkers of vedolizumab resistance and underlying inflammatory pathways involved in IBD

    Soendergaard, C., Seidelin, Jakob Benedict, Steenholdt, C. & Nielsen, Ole Haagen, 2018, In: B M J Open Gastroenterology. 5, 1, e000208.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. 2017
  63. Published

    Primary monocytes derived from ulcerative colitis show no difference in the TNF-alpha-induced immune response among responders and primary non-responders to infliximab

    Li, Y., Jensen, Kim Bak, Seidelin, Jakob Benedict & Nielsen, O. H., Sep 2017, In: Journal of Gastroenterology and Hepatology. 32, S3, p. 138-138 P-0750.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  64. Published

    Asymptomatic carriers contribute to nosocomial Clostridium difficile infection: a cohort study of 4508 patients

    Blixt, T., Gradel, K. O., Homann, C., Seidelin, Jakob Benedict, Schønning, Kristian, Lester, A., Houlind, J., Stangerup, M., Gottlieb, M. & Knudsen, J. D., 2017, In: Gastroenterology. 152, 5, p. 1031-1041.e2

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Culturing human intestinal stem cells for regenerative applications in the treatment of inflammatory bowel disease

    Holmberg, F. E., Seidelin, Jakob Benedict, Yin, X., Mead, B. E., Tong, Z., Li, Yuan, Karp, J. M. & Nielsen, Ole Haagen, 2017, In: EMBO Molecular Medicine. 9, 5, p. 558-570 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  66. Published

    Relation between NOD2 genotype and changes in innate signaling in Crohn's disease on mRNA and miRNA levels

    Chen, Y., Salem, M., Boyd, M., Lange, Jette Bornholdt, Li, Yuan, Coskun, M., Seidelin, Jakob Benedict, Sandelin, Albin Gustav & Nielsen, Ole Haagen, 2017, In: npj Genomic Medicine. 2, 11 p., 3.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. 2016
  68. Published

    Systemic and intestinal levels of factor XIII-A: the impact of inflammation on expression in macrophage subtypes

    Søndergaard, C., Kvist, P. H., Seidelin, Jakob Benedict, Pelzer, H. & Nielsen, Ole Haagen, Aug 2016, In: Journal of Gastroenterology. 51, 8, p. 796-807 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Will novel oral formulations change the management of inflammatory bowel disease?

    Nielsen, Ole Haagen, Seidelin, Jakob Benedict, Ainsworth, M. A. & Coskun, M., 2016, In: Expert Opinion on Investigational Drugs. 25, 6, p. 709-718 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  70. 2015
  71. Published

    GM6001 Increases Anastomotic Leakage following Colonic Obstruction Possibly by Impeding Epithelialization

    Rehn, M., Krarup, P., Christensen, L. H., Seidelin, Jakob Benedict, Ågren, Magnus & Syk, I., Nov 2015, In: Surgical Infections. 16, 6, p. 702-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Impact of T300A Variant of ATG16L1 on Antibacterial Response, Risk of Culture Positive Infections, and Clinical Course of Crohn's Disease

    Salem, M., Nielsen, Ole Haagen, Nys, K., Yazdanyar, S. & Seidelin, Jakob Benedict, Nov 2015, In: Clinical and Translational Gastroenterology. 6, 9 p., e122.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Alpha-1 antitrypsin and granulocyte colony-stimulating factor as serum biomarkers of disease severity in ulcerative colitis

    Soendergaard, C., Nielsen, Ole Haagen, Seidelin, Jakob Benedict, Kvist, P. H. & Bjerrum, J. T., May 2015, In: Inflammatory Bowel Diseases. 21, 5, p. 1077-88 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    ATG16L1: A multifunctional susceptibility factor in Crohn disease

    Salem, M., Ammitzboell, M., Nys, K., Seidelin, Jakob Benedict & Nielsen, Ole Haagen, 3 Apr 2015, In: Autophagy. 11, 4, p. 585-94 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Species-specific engagement of human nucleotide oligomerization domain 2 (NOD)2 and Toll-like receptor (TLR) signalling upon intracellular bacterial infection: role of Crohn's associated NOD2 gene variants

    Salem, M., Seidelin, Jakob Benedict, Eickhardt-Dalbøge, S. R., Alhede, M., Rogler, G. & Nielsen, Ole Haagen, Mar 2015, In: Clinical and Experimental Immunology. 179, 3, p. 426-34 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    IL-33 promotes GATA-3 polarization of gut-derived T cells in experimental and ulcerative colitis

    Seidelin, Jakob Benedict, Coskun, M., Kvist, P. H., Holm, T. L., Holgersen, Kristine & Nielsen, Ole Haagen, Feb 2015, In: Journal of Gastroenterology. 50, 2, p. 180-190 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Cellular inhibitor of apoptosis protein 2 controls human colonic epithelial restitution, migration, and Rac1 activation

    Seidelin, Jakob Benedict, Larsen, S., Linnemann, D., Vainer, B., Coskun, M., Troelsen, J. T. & Nielsen, Ole Haagen, Jan 2015, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 308, 2, p. G92-G99 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Objective Quantification of Immune Cell Infiltrates and Epidermal Proliferation in Psoriatic Skin: A Comparison of Digital Image Analysis and Manual Counting

    Soendergaard, C., Nielsen, Ole Haagen, Skak, K., Røpke, M. A., Seidelin, Jakob Benedict & Kvist, P. H., 2015, In: Applied Immunohistochemistry & Molecular Morphology. p. 1-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Regulation of antiapoptotic and cytoprotective pathways in colonic epithelial cells in ulcerative colitis

    Seidelin, Jakob Benedict, 2015, In: Scandinavian Journal of Gastroenterology. 50 , Suppl 1, p. 1-29 29 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. 2014
  81. Published

    Inhibitors of apoptosis (IAPs) regulate intestinal immunity and inflammatory bowel disease (IBD) inflammation

    Pedersen, J., LaCasse, E. C., Seidelin, Jakob Benedict, Coskun, M. & Nielsen, Ole Haagen, Nov 2014, In: Trends in Molecular Medicine. 20, 11, p. 652-65 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Identification of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2

    Boyd, M., Coskun, M., Lilje, B., Andersson, Robin, Hoof, I., Lange, Jette Bornholdt, Dahlgaard, K., Olsen, Jørgen, Vitezic, M., Bjerrum, Jakob Tveiten , Seidelin, Jakob Benedict, Nielsen, Ole Haagen, Troelsen, J. & Sandelin, Albin Gustav, 2014, In: D N A Research. 21, 6, p. 569-583 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. 2013
  84. Published

    miR-20b, miR-98, miR-125b-1*, and let-7e* as new potential diagnostic biomarkers in ulcerative colitis

    Coskun, M., Bjerrum, Jakob Tveiten , Seidelin, Jakob Benedict, Troelsen, J., Olsen, Jørgen & Nielsen, Ole Haagen, 21 Jul 2013, In: World Journal of Gastroenterology. 19, 27, p. 4289-99 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    ERK controls epithelial cell death receptor signalling and cellular FLICE-like inhibitory protein (c-FLIP) in ulcerative colitis

    Seidelin, Jakob Benedict, Coskun, M., Vainer, B., Riis, Lene Buhl, Soendergaard, C. & Nielsen, Ole Haagen, Jul 2013, In: Journal of Molecular Medicine. 91, 7, p. 839-49 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Noninfectious & noninflammatory bowel disease colitis

    Nielsen, Ole Haagen, Bjerrum, Jakob Tveiten & Seidelin, Jakob Benedict, 1 Mar 2013, Advances in the Management of Inflammatory Bowel Disease. Future Medicine Ltd., p. 33-49 17 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  87. Published

    Caspase 14 does not influence intestinal epithelial cell differentiation

    Seidelin, Jakob Benedict, Sträter, J. & Nielsen, Ole Haagen, Mar 2013, In: Cell Death and Differentiation. 20, 3, p. 524

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Colitis ulcerosa

    Nielsen, Ole Haagen, Jess, T., Bjerrum, Jakob Tveiten & Seidelin, Jakob Benedict, 2013, In: Ugeskrift for Laeger. 175, 20, p. 1412-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Expression profiling of apoptosis-related genes in enterocytes isolated from patients with ulcerative colitis

    Seidelin, Jakob Benedict & Nielsen, Ole Haagen, 2013, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 114, 7-8, p. 508-17 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Mucosal healing in ulcerative colitis: pathophysiology and pharmacology

    Seidelin, Jakob Benedict, Coskun, M. & Nielsen, Ole Haagen, 2013, In: Advances in Clinical Chemistry. 59, p. 101-23 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Muramyl dipeptide responsive pathways in Crohn's disease: from NOD2 and beyond

    Salem, M., Seidelin, Jakob Benedict, Rogler, G. & Nielsen, Ole Haagen, 2013, In: Cellular and Molecular Life Sciences. 70, p. 3391-3404

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Tissue regenerating functions of coagulation factor XIII

    Soendergaard, C., Kvist, P. H., Seidelin, Jakob Benedict & Nielsen, Ole Haagen, 2013, In: Journal of Thrombosis and Haemostasis.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. 2012
  94. Published

    Biological treatment of Crohn's disease

    Nielsen, Ole Haagen, Bjerrum, J. T., Seidelin, Jakob Benedict, Nyberg, C. & Ainsworth, M., 2012, In: Digestive Diseases. 30 Suppl 3, p. 121-33 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    MicroRNAs in inflammatory bowel disease--pathogenesis, diagnostics and therapeutics

    Coskun, M., Bjerrum, J. T., Seidelin, Jakob Benedict & Nielsen, Ole Haagen, 2012, In: World Journal of Gastroenterology. 18, 34, p. 4629-34 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Outcome after discontinuation of infliximab in patients with inflammatory bowel disease in clinical remission: an observational Danish single center study

    Steenholdt, C., Molazahi, A., Ainsworth, M. A., Brynskov, J., Thomsen, O. Ø. & Seidelin, Jakob Benedict, 2012, In: Scandinavian Journal of Gastroenterology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    pcaGoPromoter--an R package for biological and regulatory interpretation of principal components in genome-wide gene expression data

    Hansen, M., Gerds, Thomas Alexander, Nielsen, Ole Haagen, Seidelin, Jakob Benedict, Troelsen, J. T. & Olsen, Jørgen, 2012, In: P L o S One. 7, 2, p. e32394

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. 2011
  99. Published

    A role for interleukin-33 in T(H)2-polarized intestinal inflammation?

    Seidelin, Jakob Benedict, Rogler, G. & Nielsen, Ole Haagen, Sep 2011, In: Mucosal Immunology. 4, 5, p. 496-502 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  100. Published

    Use of biological molecules in the treatment of inflammatory bowel disease

    Nielsen, Ole Haagen, Seidelin, Jakob Benedict, Munck, Lars Kristian & Rogler, G., Jul 2011, In: Journal of Internal Medicine. 270, 1, p. 15-28 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    Pathogenesis and biomarkers of carcinogenesis in ulcerative colitis

    Thorsteinsdottir, S., Gudjónsson, Thorkell, Nielsen, Ole Haagen, Vainer, B. & Seidelin, Jakob Benedict, 7 Jun 2011, In: Nature Reviews. Gastroenterology & Hepatology. 8, 7, p. 395-404 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  102. Published

    A role for interleukin-33 in T(H)2-polarized intestinal inflammation?

    Seidelin, Jakob Benedict, Rogler, G. & Nielsen, Ole Haagen, 2011, In: Mucosal Immunology. 4, 5, p. 496-502 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  103. Published

    MAP kinases in inflammatory bowel disease

    Coskun, M., Olsen, Jørgen, Seidelin, Jakob Benedict & Nielsen, Ole Haagen, 2011, In: Clinica Chimica Acta. 412, 7-8, p. 513-20 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  104. 2010
  105. Published

    IL-33 is upregulated in colonocytes of ulcerative colitis

    Seidelin, Jakob Benedict, Bjerrum, Jakob Tveiten , Coskun, M., Widjaya, B., Vainer, B., Nielsen, Ole Haagen, Seidelin, J. B., Bjerrum, J. T., Coskun, M., Widjaya, B., Vainer, B. & Nielsen, Ole Haagen, 2010, In: Immunology Letters. 128, 1, p. 80-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  106. 2009
  107. Published

    Betydningen af mikroribonukleinsyre for sygdomsudvikling

    Widjaya, B., Seidelin, Jakob Benedict, Olsen, Jørgen & Nielsen, Ole Haagen, 16 Nov 2009, In: Ugeskrift for Laeger. 171, 47, p. 3441-4 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  108. Published

    Samtidig leptospirose og salmonellainfektion

    Rönsholt, F. F., Seidelin, Jakob Benedict & Villumsen, S., 4 May 2009, In: Ugeskrift for Laeger. 171, 19, p. 1607-9 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  109. Published

    Aeromedical transport after acute myocardial infarction

    Seidelin, Jakob Benedict, Bruun, Niels Eske & Nielsen, H., 2009, In: Journal of Travel Medicine. 16, 2, p. 96-100 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  110. Published

    Diagnosis of ulcerative colitis before onset of inflammation by multivariate modeling of genome-wide gene expression data

    Olsen, Jørgen, Gerds, Thomas Alexander, Seidelin, Jakob Benedict, Csillag, C., Bjerrum, Jakob Tveiten , Troelsen, J. T. & Nielsen, Ole Haagen, 2009, In: Inflammatory Bowel Diseases. 15, 7, p. 1032-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  111. Published

    Epithelial apoptosis: cause or consequence of ulcerative colitis?

    Seidelin, Jakob Benedict & Nielsen, Ole Haagen, 2009, In: Scandinavian Journal of Gastroenterology. 44, 12, p. 1429-34 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  112. Published

    Evidence for impaired CARD15 signalling in Crohn's disease without disease linked variants

    Seidelin, Jakob Benedict, Broom, O. J., Olsen, Jørgen & Nielsen, Ole Haagen, 2009, In: PLoS ONE. 4, 11, p. e7794

    Research output: Contribution to journal › Journal article › Research › peer-review

  113. 2008
  114. Published

    Attenuated apoptosis response to Fas-ligand in active ulcerative colitis

    Seidelin, Jakob Benedict & Nielsen, Ole Haagen, Dec 2008, In: Inflammatory Bowel Diseases. 14, 12, p. 1623-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  115. 2007
  116. Published

    Upregulation of cIAP2 in regenerating colonocytes in ulcerative colitis

    Seidelin, Jakob Benedict, Vainer, B., Andresen, Lars & Nielsen, Ole Haagen, 2007, In: Virchows Archiv. 451, 6, p. 1031-1038 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  117. 2006
  118. Published

    Regulering af cytokindannelse ved inflammatoriske tarmsygdomme

    Ferrero-Miliani, L., Seidelin, Jakob Benedict & Nielsen, Ole Haagen, 8 May 2006, In: Ugeskrift for Laeger. 168, 19, p. 1847-50 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  119. Published

    Transdermal nikotinbehandling af colitis ulcerosa: gennemgang af et Cochrane-review

    Seidelin, Jakob Benedict & Nielsen, Ole Haagen, 13 Feb 2006, In: Ugeskrift for Laeger. 168, 7, p. 674-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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