David Paul Drucker Woldbye

David Paul Drucker Woldbye

Associate Professor

ORCID: 0000-0002-6321-3850

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  1. Published

    α-Synuclein Overexpression Increases Dopamine D2/3 Receptor Binding and Immune Activation in a Model of Early Parkinson's Disease

    Stokholm, K., Thomsen, M. B., Phan, J., Moller, L. K., Bay-Richter, C., Christiansen, S. H., Woldbye, David Paul Drucker, Romero-Ramos, M. & Landau, A. M., 2021, In: Biomedicines. 9, 12, 16 p., 1876.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Y5 neuropeptide Y receptor overexpression in mice neither affects anxiety- and depression-like behaviours nor seizures but confers moderate hyperactivity.

    Olesen, M. V., Christiansen, S. H. O., Gøtzsche, C. R., Holst, Birgitte, Kokaia, M. & Woldbye, David Paul Drucker, 2012, In: Neuropeptides (Sheffield). 46, 2, p. 71-9

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Visualization of Functional Neuropeptide Y Receptors in the Mouse Hippocampus and Neocortex Using [35S]GTPγS Binding

    Elbrønd-Bek, H., Gøtzsche, C. R., Skinbjerg, M., Christensen, D. Z., Plenge, P. K. & Woldbye, David Paul Drucker, 2015, In: International Journal of Peptide Research and Therapeutics. 21, 3, p. 269-278 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Unaltered neuropeptide Y (NPY)-stimulated [35S]GTPgamma-S binding suggests a net increase in NPY signalling after repeated electroconvulsive seizures in mice

    Christensen, D. Z., Olesen, M. V., Kristiansen, H., Mikkelsen, J. D. & Woldbye, David Paul Drucker, 2006, In: Journal of Neuroscience Research. 84, 6, p. 1282-1291 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Translational approach for gene therapy in epilepsy: Model system and unilateral overexpression of neuropeptide Y and Y2 receptors

    Ledri, L. N., Melin, E., Christiansen, S. H., Gøtzsche, C. R., Cifra, A., Woldbye, David Paul Drucker & Kokaia, M., Feb 2016, In: Neurobiology of Disease. 86, p. 52-61 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Transcriptome analysis in patients with temporal lobe epilepsy

    Kjær, C., Barzaghi, G., Bak, Lasse Kristoffer, Goetze, Jens P. , Yde, C. W., Woldbye, David Paul Drucker, Pinborg, Lars Hageman & Jensen, Lars Juhl, 2019, In: Brain. 142, 10, p. 49-64 16 p., e55.

    Research output: Contribution to journal › Letter › Research › peer-review

  7. Published

    Towards automatic glaucoma assessment: An Encoder-decoder CNN for Retinal Layer Segmentation in Rodent OCT images

    Del Amor, R., Morales, S., Colomer, A., Mossi, J. M., Woldbye, David Paul Drucker, Klemp, Kristian, Larsen, M. & Naranjo, V., Sep 2019, EUSIPCO 2019 - 27th European Signal Processing Conference. European Signal Processing Conference, EUSIPCO, (European Signal Processing Conference, Vol. 2019-September).

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

  8. Published

    Theory of Visual Attention (TVA) applied to mice in the 5-choice serial reaction time task

    Fitzpatrick, C. M., Caballero-Puntiverio, M., Gether, Ulrik, Habekost, Thomas, Bundesen, C., Vangkilde, Signe, Woldbye, David Paul Drucker, Andreasen T., Jesper & Petersen, Anders, 2017, In: Psychopharmacology. 234, 5, p. 845-855

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The short/long polymorphism in the serotonin transporter gene promoter is not associated with panic disorder in a Scandinavian sample

    Olesen, O. F., Bennike, B. G., Steno-Hansen, E., Koefoed, P., Woldbye, David Paul Drucker, Bolwig, T. G. & Mellerup, Erling Thyge, 2005, In: Psychiatric Genetics. Vol. 15, p. 159

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The role of NPY in learning and memory

    Gøtzsche, C. R. & Woldbye, David Paul Drucker, 1 Feb 2016, In: Neuropeptides. 55, p. 79-89 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  11. Published

    The norepinephrine transporter gene is a candidate gene for panic disorder

    Buttenschøn, H. N., Kristensen, A. S., Buch, H. N., Andersen, J. H., Bonde, Jens Peter, Grynderup, M. B., Hansen, Åse Marie, Kolstad, H., Kaergaard, A., Kaerlev, L., Mikkelsen, S., Thomsen, Jane Frølund, Koefoed, P., Erhardt, A., Woldbye, David Paul Drucker, Børglum, A. & Mors, O., 1 Jun 2011, In: Journal of Neural Transmission. 118, 6, p. 969-76 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The neuropeptide galanin promotes neuronal differentiation in murine subventricular zone cultures

    Agasse, F., Christiansen, S. H. O., Malva, J. & Woldbye, David Paul Drucker, 2013, In: Stem Cells and Development. 22, 11, p. 1693-1708 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The how and Y of eating

    Woldbye, David Paul Drucker & Larsen, P. J., 1998, In: Nature Medicine. Vol 4, No 6, p. 671-672

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The dorsomedial hypothalamus and nucleus of the solitary tract as key regulators in a rat model of chronic obesity

    Zhang, C., Barkholt, P., Nielsen, J. C., Thorbek, D. D., Rigbolt, K., Vrang, N., Woldbye, David Paul Drucker & Jelsing, J., 2020, In: Brain Research. 1727, 146538.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The C-terminal flanking peptide of neuropeptide Y (NPY) is not essential for seizure-suppressant actions of prepro-NPY overexpression in male rats

    Soud, K., Jørgensen, Søren Heide, Woldbye, David Paul Drucker & Sørensen, Andreas Toft, 2019, In: Journal of Neuroscience Research. 97, 3, p. 362-372 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Temporal gene expression profile after acute electroconvulsive stimulation in the rat.

    Dyrvig, M., Christiansen, S. H. O., Woldbye, David Paul Drucker & Lichota, J., 2014, In: Gene. 539, 1, p. 8-14 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Synaptic degeneration and remodelling after fast kindling of the olfactory bulb.

    Woldbye, David Paul Drucker, Bolwig, T. G., Kragh, J. & Jørgensen, O. S., 1996, In: Neurochemical Research. 21, 5, p. 585-93 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Sustained overexpression of neuropeptide S in the amygdala reduces anxiety-like behavior in rats

    Tillmann, S., Skibdal, H. E., Christiansen, S. H., Gøtzsche, C. R., Hassan, M., Mathe, A. A., Wegener, G. & Woldbye, David Paul Drucker, 2019, In: Behavioural Brain Research. 367, p. 28-34 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Short erythropoietin-derived peptide enhances memory, improves long-term potentiation, and counteracts amyloid beta-induced pathology

    Dmytriyeva, O., Belmeguenai, A., Bezin, L., Soud, K., Woldbye, David Paul Drucker, Gotzsche, C. R. & Pankratova, Stanislava, 2019, In: Neurobiology of Aging. 81, p. 88-101 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Role for M5 muscarinic acetylcholine receptors in cocaine addiction

    Fink-Jensen, A., Fedorova, I., Wörtwein, Gitta, Woldbye, David Paul Drucker, Rasmussen, T., Thomsen, M., Bolwig, T. G., Knitowski, K. M., McKinzie, D. L., Yamada, M., Wess, J. & Basile, A., 2003, In: Journal of Neuroscience Research. 74, 1, p. 91-6

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Retinal layer segmentation in rodent OCT images: Local intensity profiles & fully convolutional neural networks

    Morales, S., Colomer, A., Mossi, J. M., del Amor, R., Woldbye, David Paul Drucker, Klemp, Kristian, Larsen, M. & Naranjo, V., 2021, In: Computer Methods and Programs in Biomedicine. 198, 105788.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Replication and meta-analysis of TMEM132D gene variants in panic disorder.

    Erhardt, A., Akula, N., Schumacher, J., Czamara, D., Karabalai, N., Müller-Myhsok, B., Mors, O., Borglum, A., Kristensen, AS., Woldbye, D. P. D., Koefoed, P., Eriksson, E., Maron, E., Metspalu, A., Nurnberger, J., Philibert, RA., Kennedy, J., Domschke, K., Reif, A., Deckert, J. & 10 others, Otowa, T., Kawamura, Y., Kaiya, H., Okazaki, Y., Tanil, H., Tokunaga, K., Sasaki, T., Ioannidis, J., McMahon, F. & Binder, E., 2012, In: Translational Psychiatry. 2:e156

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Repeated inhibitory effects of NPY on hippocampal CA3 seizures and wet dog shakes

    Klemp, K. & Woldbye, David Paul Drucker, 2001, In: Peptides. 22, 3, p. 523-527

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Regulation of the galanin system by repeated electroconvulsive seizures in mice

    Christiansen, S. H. & Woldbye, David Paul Drucker, 1 Dec 2010, In: Journal of Neuroscience Research. 88, 16, p. 3635-43 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Regulation of activity-regulated cytoskeleton protein (Arc) mRNA after acute and chronic electroconvulsive stimulation in the rat.

    Larsen, M. H., Olesen, M., Woldbye, David Paul Drucker, Hay-Schmidt, Anders, Hansen, H. H., Rønn, L. C. B. & Mikkelsen, J. D., 2005, In: Brain Research. 1064, 1-2, p. 161-5 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Reduced cocaine self-administration in muscarinic M5 acetylcholine receptor-deficient mice

    Thomsen, M. M., Woldbye, David Paul Drucker, Wörtwein, Gitta, Fink-Jensen, A., Wess, J. & Caine, S. B., 2005, In: Journal of Neuroscience. Vol. 25, p. 8141-49

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Rapid activation of the extracellular signal-regulated kinase 1/2 (ERK1/2) signaling pathway by electroconvulsive shock in the rat prefrontal cortex is not associated with TrkB neurotrophin receptor activation

    Hansen, H. H., Rantamaki, T. P. J., Larsen, M. H., Woldbye, David Paul Drucker, Mikkelsen, J. D. & Castren, E. H., 2007, In: Cellular and Molecular Neurobiology. 27, 5, p. 585-594 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Protein kinase C activity blocks neuropeptide Y-mediated inhibition of glutamate release and contributes to excitability of the hippocampus in status epilepticus

    Silva, A. P., Lourenco, J., Xapelli, S., Ferreira, R., Kristiansen, H., Woldbye, David Paul Drucker, Oliveira, C. R. & Malva, J. O., 2007, In: The FASEB Journal. 21, 3, p. 671-681 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Prolonged life of human acute hippocampal slices from temporal lobe epilepsy surgery

    Wickham, J., Brödjegård, N. G., Vighagen, R., Pinborg, Lars Hageman, Bengzon, J., Woldbye, David Paul Drucker, Kokaia, M. & Andersson, M., 2018, In: Scientific Reports. 8, 13 p., 4158.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Prolonged induction of c-fos in neuropeptide Y- and somatostatin-immunoreactive neurons of the rat dentate gyrus after electroconvulsive stimulation.

    Woldbye, David Paul Drucker, Greisen, M. H., Bolwig, T. G., Larsen, Jacob & Mikkelsen, J. D., 1996, In: Brain Research. 720, 1-2, p. 111-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Powerful inhibition of kainic acid seizures by neuropeptide Y via Y5-like receptors

    Woldbye, David Paul Drucker, Larsen, P. J., Mikkelsen, J. D., Klemp, K., Madsen, T. M. & Bolwig, T. G., 1997, In: Nature Medicine. 3, 7, p. 761-764

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    PICK1 deficiency impairs secretory vesicle biogenesis and leads to growth retardation and decreased glucose tolerance

    Holst, Birgitte, Madsen, Kenneth Lindegaard, Jansen, A. M., Jin, C., Rickhag, Karl Mattias, Lund, Viktor Karlovich, Jensen, M., Bhatia, V., Sørensen, G., Madsen, A. N., Xue, Z., Møller, S. K., Woldbye, David Paul Drucker, Qvortrup, Klaus, Huganir, R., Stamou, Dimitrios, Kjærulff, Ole & Gether, Ulrik, Apr 2013, In: P L o S Biology (Online). 11, 4, p. 1-25 25 p., e1001542.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Optogenetik bringer neurale mekanismer frem i lyset og kan blive en ny terapiform

    Axelsen, T. M., Navntoft, C. A. E., Christiansen, S. H., Dreyer, J. K., Sørensen, Jakob Balslev, Gether, Ulrik & Woldbye, David Paul Drucker, 17 Aug 2015, In: Ugeskrift for Laeger. 177, 34, p. 2-5 4 p., V06150501.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Optogenetic control of human neurons in organotypic brain cultures

    Andersson, M., Avaliani, N., Svensson, A., Wickham, J., Pinborg, Lars Hageman, Jespersen, B., Christiansen, S. H., Bengzon, J., Woldbye, David Paul Drucker & Kokaia, M., 21 Apr 2016, In: Scientific Reports. 6, 5 p., 24818.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    No loss of hippocampal hilar somatostatinergic neurons after repeated electroconvulsive shock: a combined stereological and in situ hybridization study

    Dalby, N. O., Tonder, N., Woldbye, David Paul Drucker, West, M., Finsen, B. & Bolwig, T. G., 1996, In: Biological Psychiatry. 40 (1), p. 54-60

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    No association between the -399 C > T polymorphism of the neuropeptide Y gene and schizophrenia, unipolar depression or panic disorder in a Danish population

    Lindberg, C., Koefoed, P., Hansen, E. S., Bolwig, T. G., Rehfeld, J. F., Mellerup, E., Jorgensen, O. S., Kessing, L. V., Werge, T., Haugbol, S., Wang, A. G. & Woldbye, David Paul Drucker, 2006, In: Acta Psychiatrica Scandinavica. 113, 1, p. 54-58 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    No Loss of somatostatin-immunoreactive neurons in the hippocampal dentate hilus of alcohol-withdrawal kindled rats

    Ulrichsen, J., Woldbye, David Paul Drucker, Olsen, C. H., Haugbøl, S., Bolwig, T. G. & Hemmingsen, R., 1996, In: Alcohol & Alcoholism. 31, 4, p. 411-419

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Neurotrophic effects of vascular endothelial growth factor B and novel mimetic peptides on neurons from the central nervous system

    Dmytriyeva, O., de Diego Ajenjo, A., Jørgensen, Kathrine Lundø, Hertz, H., Rasmussen, K. K., Christiansen, A. T., Klingelhofer, J., Nielsen, A. L., Hoeber, J., Kozlova, E. N., Woldbye, David Paul Drucker & Pankratova, Stanislava, 2020, In: ACS Chemical Neuroscience. 11, 9, p. 1270–1282 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Neuropeptide y promotes neurogenesis in murine subventricular zone

    Agasse, F., Bernardino, L., Kristiansen, H., Christiansen, S. H., Ferreira, R., Silva, B., Grade, S., Woldbye, David Paul Drucker, Malva, J. O. & Kristiansen, H., 2008, In: Stem Cells. 26, 6, p. 1636-45 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Neuropeptide Y-stimulated [(35) S]GTPγs functional binding is reduced in the hippocampus after kainate-induced seizures in mice

    Elbrønd-Bek, H., Olling, J. D., Gøtzsche, C. R., Waterfield, A., Wörtwein, Gitta & Woldbye, David Paul Drucker, 9 Jul 2014, In: Synapse. 68, 10, p. 427-36 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Neuropeptide Y treatment induces retinal vasoconstriction and causes functional and histological retinal damage in a porcine ischaemia model

    Christiansen, A. T., Sørensen, N. B., Haanes, K. A., Blixt, F. W., la Cour, Morten, Warfvinge, K., Klemp, Kristian, Woldbye, David Paul Drucker & Kiilgaard, Jens Folke, 2018, In: Acta Ophthalmologica. 96, 8, p. 812-820 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Neuropeptide Y system mRNA expression changes in the hippocampus of a type I diabetes rat model

    Campos, E. J., Martins, J., Brudzewsky, D., Woldbye, David Paul Drucker & Ambrósio, A. F., 2020, In: Annals of Anatomy. 227, 8 p., 151419.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Neuropeptide Y is Up-regulated and Induces Antinociception in Cancer-induced Bone Pain.

    Diaz del Castillo, M., Christiansen, S. H., Appel, C., Falk, S., Woldbye, David Paul Drucker & Heegaard, Anne-Marie, 29 May 2018, In: Neuroscience. 384, p. 111-119

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Neuropeptide Y inhibits hippocampal seizures and wet dog shakes.

    Woldbye, David Paul Drucker, Madsen, T. M., Larsen, Jacob, Mikkelsen, J. D. & Bolwig, T. G., 1996, In: Brain Research. 737, 1-2, p. 162-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Neuropeptide Y inhibits in vitro epileptiform activity in the entorhinal cortex of mice

    Woldbye, David Paul Drucker, Nanobashvili, A., Husum, H., Bolwig, T. G. & Kokaia, M., 2002, In: Neurosc. Lett.. 333, 2, p. 127-30

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Neuropeptide Y infusion into the shell region of the rat nucleus accumbens increases extracellular levels of dopamine

    Sørensen, G., Wegener, G., Hasselstrøm, J., Hansen, T. V. O., Wörtwein, Gitta, Fink-Jensen, Anders & Woldbye, David Paul Drucker, 2009, In: NeuroReport. 20, 11, p. 1023-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Neuropeptide Y genes and suicidal behaviour among schizophrenic patients

    Wang, August Gabriel, Koefoed, P., Jacoby, A. S., Woldbye, David Paul Drucker, Rasmussen, Henrik Berg, Timm, S., Dam, H., Jakobsen, K. D., Nordentoft, Merete, Jürgens, Gesche, Sorensen, H. J., Garsdal, O., Hvid, M. & Werge, Thomas, Jun 2013, In: Psychiatric Genetics. 23, 3, p. 139-40 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Neuropeptide Y and seizures: effects of exogenously applied ligands

    Woldbye, David Paul Drucker & Kokaia, M., 2004, In: Neuropeptides. Vol. 38, no.4, p. 253-60

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Neuropeptide Y and its involvement in chronic pain

    Diaz-delCastillo, M., Woldbye, David Paul Drucker & Heegaard, Anne-Marie, 1 Sep 2018, In: Neuroscience. 387, p. 162-169 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  50. Published

    Neuropeptide Y Y5 receptors suppress in vitro spontaneous epileptiform in the rat hippocampus

    Nanobashvili, A., Woldbye, David Paul Drucker, Husum, H., Bolwig, T. G. & Kokaia, M., 2004, In: NeuroReport. 15, 2, p. 339-43

    Research output: Contribution to journal › Journal article › Research › peer-review

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