Lars Hviid

Lars Hviid

Professor

Member of:

  • SURFACE team

ORCID: 0000-0002-1698-4927

Publication year:
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  1. Published

    In vitro selection for adhesion of Plasmodium falciparum-infected erythrocytes to ABO antigens does not affect PfEMP1 and RIFIN expression

    van der Puije, W., Wang, Christian William, Sudharson, S., Hempel, C., Olsen, Rebecca Wendelboe, Dalgaard, Nanna, Ofori, M. F., Hviid, Lars, Kurtzhals, Jørgen & Staalsø, Trine, 2020, In: Scientific Reports. 10, 1, p. 12871 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Immune selection and within-host competition can structure the repertoire of variant surface antigens in Plasmodium falciparum -a mathematical model

    van Noort, S. P., Nunes, M. C., Weedall, G. D., Hviid, Lars & Gomes, M. G. M., 2010, In: PLoS ONE. 5, 3, p. e9778

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    In vitro Plasmodium falciparum drug sensitivity assay: inhibition of parasite growth by incorporation of stomatocytogenic amphiphiles into the erythrocyte membrane

    Ziegler, H. L., Stærk, Dan, Christensen, J., Hviid, Lars, Hägerstrand, H. & Jaroszewski, J. W., 2002, In: Antimicrobial Agents and Chemotherapy. 46, 5, p. 1441-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Prevalence and dynamic changes in lung ultrasound findings among adults with uncomplicated malaria and controls in the Amazon basin, Brazil

    Wegener, A., Holm, A. E., Gomes, L. C., Lima, K. O., Matos, L. O., Vieira, I. V. M., Kaagaard, M. D., de Souza, R. M., Hviid, Lars, Guimarães Lacerda, M. V., Vestergaard, L. S., Farias Marinho, C. R., Platz, E., Biering-Sørensen, Tor, Silvestre, O. M. & Brainin, P., 2022, In: American Journal of Tropical Medicine and Hygiene. 106, 6, p. 1637-1645 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Rifins, rosetting, and red blood cells

    Wang, Christian William & Hviid, Lars, Jul 2015, In: Trends in Parasitology. 31, 7, p. 285-6 2 p.

    Research output: Contribution to journal › Journal article › Commissioned › peer-review

  6. Published

    Acquisition and decay of IgM and IgG responses to merozoite antigens after Plasmodium falciparum malaria in Ghanaian children

    Walker, Melanie Rose, Knudsen, Anne Schlitterlau, Partey, Frederica Dedo, Bassi, Maria Rosaria, Frank, A. M., Castberg, F. C., Sarbah, E. W., Ofori, M. F., Hviid, Lars & Barfod, Lea Klingenberg, 2020, In: PLoS ONE. 15, 12, p. e0243943

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Differences in human antibody reactivity to Plasmodium falciparum variant surface antigens are dependent on age and malaria transmission intensity in northeastern Tanzania

    Vestergaard, L. S., Lusingu, J. P., Nielsen, Morten Agertoug, Mmbando, B. P., Dodoo, D., Akanmori, B. D., Alifrangis, Michael, Bygbjerg, Ib Christian, Lemnge, M. M., Staalsoe, T., Hviid, Lars & Theander, Thor Grundtvig, 2008, In: Infection and Immunity. 76, 6, p. 2706-14 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The concentration of the C-type lectin, mannan-binding protein, in human plasma increases during an acute phase response

    Thiel, S., Holmskov, U., Hviid, Lars, Laursen, S. B. & Jensenius, J. C., 1992, In: Clinical and Experimental Immunology. 90, 1, p. 31-5 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Selection of glutamate-rich protein long synthetic peptides for vaccine development: antigenicity and relationship with clinical protection and immunogenicity

    Theisen, M., Dodoo, D., Toure-Balde, A., Soe, S., Corradin, G., Koram, K. K., Kurtzhals, Jørgen, Hviid, Lars, Theander, Thor Grundtvig, Akanmori, B., Ndiaye, M. & Druilhe, P., 2001, In: Infection and Immunity. 69, 9, p. 5223-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Compounds useful in the diagnosis and treatment of pregnancy-associated malaria

    Theander, Thor Grundtvig, Salanti, Ali, Hviid, Lars, Staalsø, Trine, Jensen, Anja Ramstedt, Lavstsen, Thomas & Dahlbäck, M., 2004, Patent No. WO2004067559 A1, Priority date 27 Jan 2003, Priority No. WO2004067559 A1

    Research output: Patent

  11. Published

    Activation of CD8-positive suppressor cells during the malaria season

    Theander, Thor Grundtvig, Hviid, Lars, Abu-Zeid, Y. A., Abdulhadi, N. H., Saeed, B. O., Jakobsen, P. H., Jepsen, S., Bayoumi, R. A. & Jensen, J. B., 1993, In: Immunology and Infectious Diseases. 3, p. 97-102

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Reduced cellular immune reactivity in healthy individuals during the malaria transmission season

    Theander, Thor Grundtvig, Hviid, Lars, Abu-Zeid, Y. A., Abdulhadi, N. H., Saeed, B. O., Jakobsen, P. H., Reimert, C. M., Jepsen, S., Bayoumi, R. A. & Jensen, J. B., 1990, In: Immunology Letters. 25, 1-3, p. 237-42 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Cell-mediated immunity to Plasmodium falciparum infection: evidence against the involvement of cytotoxic lymphocytes

    Theander, Thor Grundtvig, Andersen, B. J., Pedersen, B. K., Jepsen, S., Bygbjerg, Ib Christian, Hviid, Lars, Larsen, P. B. & Kharazmi, A., 1988, In: Scandinavian Journal of Immunology. 28, 1, p. 105-11 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Human T-cell recognition of synthetic peptides representing conserved and variant sequences from the merozoite surface protein 2 of Plasmodium falciparum

    Theander, Thor Grundtvig, Hviid, Lars, Dodoo, D., Afari, E. A., Jensen, J. B. & Rzepczyk, C. M., 1997, In: Immunology Letters. 58, 1, p. 1-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    ICAM-1-binding Plasmodium falciparum erythrocyte membrane protein 1 variants elicits opsonic-phagocytosis IgG responses in Beninese children

    Suurbaar, Jennifer, Moussiliou, A., Tahar, R., Olsen, Rebecca Wendelboe, Adams, Yvonne, Dalgaard, Nanna, Baafour, E. K., Adukpo, S., Hviid, Lars, Kusi, K. A., Alao, J., Ofori, M. F., Ndam, N. T. & Jensen, Anja Ramstedt, 2022, In: Scientific Reports. 12, 12994.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Plasmodium falciparum-infected erythrocyte knob density is linked to the PfEMP1 variant expressed

    Subramani, R., Quadt, K., Jeppesen, A. E., Hempel, C., Petersen, J. E. V., Hassenkam, Tue, Hviid, Lars & Barfod, Lea Klingenberg, 2015, In: mBio. 6, 5, 7 p., e01456-15.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Investigating the function of Fc -specific binding of IgM to Plasmodium falciparum erythrocyte membrane protein 1 mediating erythrocyte rosetting

    Stevenson, L., Huda, P., Jeppesen, A., Laursen, E. T. F., Rowe, J. A., Craig, A., Streicher, W., Barfod, Lea Klingenberg & Hviid, Lars, Jun 2015, In: Cellular Microbiology. 17, 6, p. 819-31 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    α2-macroglobulin can crosslink multiple Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) molecules and may facilitate adhesion of parasitized erythrocytes

    Stevenson, L., Laursen, E., Cowan, G. J., Bandoh, B., Barfod, Lea Klingenberg, Cavanagh, D. R., Andersen, G. R. & Hviid, Lars, Jul 2015, In: P L o S Pathogens. 11, 7, p. 1-19 19 p., e1005022.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Novel Plasmodium falciparum malaria vaccines: evidence-based searching for variant surface antigens as candidates for vaccination against pregnancy-associated malaria

    Staalsoe, T., Jensen, Anja Ramstedt, Theander, Thor Grundtvig & Hviid, Lars, 2002, In: Immunology Letters. 84, 2, p. 133-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Intermittent preventive sulfadoxine-pyrimethamine treatment of primigravidae reduces levels of plasma immunoglobulin G, which protects against pregnancy-associated Plasmodium falciparum malaria

    Staalsoe, T., Shulman, C. E., Dorman, E. K., Kawuondo, K., Marsh, K. & Hviid, Lars, 2004, In: Infection and Immunity. 72, 9, p. 5027-30 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    In vitro selection of Plasmodium falciparum 3D7 for expression of variant surface antigens associated with severe malaria in African children

    Staalsoe, T., Nielsen, Morten Agertoug, Vestergaard, L. S., Jensen, Anja Ramstedt, Theander, Thor Grundtvig & Hviid, Lars, 2003, In: Parasite Immunology. 25, 8-9, p. 421-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Variant surface antigen-specific IgG and protection against clinical consequences of pregnancy-associated Plasmodium falciparum malaria

    Staalsoe, T., Shulman, C. E., Bulmer, J. N., Kawuondo, K., Marsh, K. & Hviid, Lars, 2004, In: Lancet. 363, 9405, p. 283-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    In vivo switching between variant surface antigens in human Plasmodium falciparum infection

    Staalsoe, T., Hamad, A. A., Hviid, Lars, Elhassan, I. M., Arnot, D. E. & Theander, Thor Grundtvig, 2002, In: Journal of Infectious Diseases. 186, 5, p. 719-22 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    The role of variant-specific immunity in asymptomatic malaria infections: maintaining a fine balance

    Staalsoe, T. & Hviid, Lars, 1998, In: Trends in Parasitology. 14, 5, p. 177-8 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Acquisition and decay of antibodies to pregnancy-associated variant antigens on the surface of Plasmodium falciparum-infected erythrocytes that protect against placental parasitemia

    Staalsoe, T., Megnekou, R., Fievét, N., Ricke, C. H., Zornig, H. D., Leke, R., Taylor, D. W., Deloron, P. & Hviid, Lars, 2001, In: Journal of Infectious Diseases. 184, 5, p. 618-26 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Detection of antibodies to variant antigens on Plasmodium falciparum-infected erythrocytes by flow cytometry

    Staalsoe, T., Giha, H. A., Dodoo, D., Theander, Thor Grundtvig & Hviid, Lars, 1999, In: Cytometry. Part B: Clinical Cytometry. 35, 4, p. 329-36 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Human monoclonal IgG selection of Plasmodium falciparum for the expression of placental malaria-specific variant surface antigens

    Soerli, J., Barfod, Lea Klingenberg, Lavstsen, Thomas, Bernasconi, N. L., Lanzavecchia, A. & Hviid, Lars, 2009, In: Parasite Immunology. 31, 6, p. 341-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Reliable cell and tissue morphology-based diagnosis of endemic Burkitt lymphoma in resource-constrained settings in Ghana

    Smith-Togobo, C., Pedersen, Mette Ølgod, Jensen, S. G., Duduyemi, B., Gyasi, R. K., Ofori, M. F., Paintsil, V., Renner, L., Nørgaard, P. & Hviid, Lars, 2019, In: BMC Cancer. 19, 7 p., 1270.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    High frequencies of tumor-infiltrating and circulating γδ T cells in endemic Burkitt lymphoma patients

    Smith-Togobo, C., Quintana Varon, Maria del Pilar, Ofori, M. F. & Hviid, Lars, 2019, In: American Journal of Tropical Medicine and Hygiene. 101, S5, p. 563-563 1830.

    Research output: Contribution to journal › Conference abstract in journal › Research

  30. Published

    Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites

    Sleebs, B. E., Lopaticki, S., Marapana, D. S., O'Neill, M. T., Rajasekaran, P., Gazdik, M., Günther, S., Whitehead, L. W., Lowes, K. N., Barfod, Lea Klingenberg, Hviid, Lars, Shaw, P. J., Hodder, A. N., Smith, B. J., Cowman, A. F. & Boddey, J. A., 2014, In: P L o S Biology. 12, 7, p. e1001897

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Structure-activity studies: in vitro antileishmanial and antimalarial activities of anthraquinones from Morinda lucida

    Sittie, A. A., Lemmich, E., Olsen, C. E., Hviid, Lars, Kharazmi, A., Nkrumah, F. K. & Christensen, Søren Brøgger, 1999, In: Planta Medica. 65, 3, p. 259-61 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Alkamides from Phyllanthus fraternus

    Sittie, A. A., Lemmich, E., Olsen, C. E., Hviid, Lars & Christensen, Søren Brøgger, 1998, In: Planta Medica. 64, 2, p. 192-3 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Plasmodium falciparum infection and naturally acquired immunity to malaria antigens among Ghanaian children in northern Ghana

    Seidu, Zakaria, Lamptey, H., Lopez-Perez, Mary, Whittle, N. O., Oppong, S. K., Kyei-Baafour, E., Pobee, A. N. A., Adjei, G. O., Hviid, Lars & Ofori, M. F., 2023, In: Parasite Epidemiology and Control. 22, p. e00317

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Clinical and laboratory characteristics of children with sickle cell disease on hydroxyurea treated with artemether-lumefantrine for acute uncomplicated malaria

    Segbefia, C., Amponsah, S. K., Afrane, A. K. A., Nyarko, M. Y., Brew, Y., Salifu, N., Ahorhorlu, S. Y., Sulley, A. M., Hviid, Lars, Ofori, M. F. & Adjei, G. O., 2023, In: Frontiers in Medicine. 10, p. 1291330

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria

    Salanti, Ali, Staalsoe, T., Lavstsen, Thomas, Jensen, Anja Ramstedt, Sowa, M. P. K., Arnot, D. E., Hviid, Lars & Theander, Thor Grundtvig, 2003, In: Molecular Microbiology. 49, 1, p. 179-91 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    A sub-family of common and highly conserved Plasmodium falciparum var genes

    Salanti, Ali, Jensen, Anja Ramstedt, Zornig, H. D., Staalsoe, T., Joergensen, L., Nielsen, Morten Agertoug, Khattab, A., Arnot, D. E., Klinkert, M. Q., Hviid, Lars & Theander, Thor Grundtvig, 2002, In: Molecular and Biochemical Parasitology. 122, 1, p. 111-5 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Evidence for the involvement of VAR2CSA in pregnancy-associated malaria

    Salanti, Ali, Dahlbäck, M., Turner, Louise, Nielsen, Morten Agertoug, Barfod, Lea Klingenberg, Magistrado, P., Jensen, Anja Ramstedt, Lavstsen, Thomas, Ofori, M. F., Marsh, K., Hviid, Lars & Theander, Thor Grundtvig, 2004, In: Journal of Experimental Medicine. 200, 9, p. 1197-203 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Detection of very low level Plasmodium falciparum infections using the nested polymerase chain reaction and a reassessment of the epidemiology of unstable malaria in Sudan

    Roper, C., Elhassan, I. M., Hviid, Lars, Giha, H., Richardson, W., Babiker, H., Satti, G. M., Theander, Thor Grundtvig & Arnot, D. E., 1996, In: American Journal of Tropical Medicine and Hygiene. 54, 4, p. 325-31 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Seasonal changes in the Plasmodium falciparum population in individuals and their relationship to clinical malaria: a longitudinal study in a Sudanese village

    Roper, C., Richardson, W., Elhassan, I. M., Giha, H., Hviid, Lars, Satti, G. M., Theander, Thor Grundtvig & Arnot, D. E., 1998, In: Parasitology. 116 ( Pt 6), p. 501-10 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Malaria in pregnancy: pathogenesis and immunity

    Rogerson, S. J., Hviid, Lars, Duffy, P. E., Leke, R. F. G. & Taylor, D. W., 2007, In: Lancet Infectious Diseases. 7, 2, p. 105-17 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Malaria

    Riley, E. M., Hviid, Lars & Theander, Thor Grundtvig, 1994, Parasitic infections and the immune system. San Diego: Academic Press, p. 119-143

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  42. Published

    Malaria

    Riley, E. M., Hviid, Lars & Theander, Thor Grundtvig, 22 Oct 2013, Parasitic Infections and the Immune System. Elsevier Science Inc., p. 119-143 25 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  43. Published

    Plasma antibodies from malaria-exposed pregnant women recognize variant surface antigens on Plasmodium falciparum-infected erythrocytes in a parity-dependent manner and block parasite adhesion to chondroitin sulfate A

    Ricke, C. H., Staalsoe, T., Koram, K., Akanmori, B. D., Riley, E. M., Theander, Thor Grundtvig & Hviid, Lars, 2000, In: Journal of Immunology. 165, 6, p. 3309-16 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA

    Raghavan, Sai Sundar Rajan, Dagil, Robert, Lopez-Perez, Mary, Conrad, J., Bassi, Maria Rosaria, Quintana Varon, Maria del Pilar, Choudhary, Swati, Gustavsson, Tobias, Wang, Y., Gourdon, Pontus Emanuel, Ofori, M. F., Christensen, S. B., Minja, D. T. R., Schmiegelow, Christentze, Nielsen, Morten Agertoug, Barfod, Lea Klingenberg, Hviid, Lars, Salanti, Ali, Lavstsen, Thomas & Wang, Kaituo, 2022, In: PLoS Pathogens. 18, 11, e1010924.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Measuring naturally acquired phagocytosis-inducing antibodies to Plasmodium falciparum parasites by a flow cytometry-based assay

    Quintana Varon, Maria del Pilar, Anabire, N. G. & Hviid, Lars, 6 Aug 2020, In: Journal of visualized experiments : JoVE. 162, e61538.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Comprehensive analysis of Fc-mediated IgM binding to the Plasmodium falciparum erythrocyte membrane protein 1 family in three parasite clones

    Quintana Varon, Maria del Pilar, Ecklu-Mensah, G., Tcherniuk, S. O., Ditlev, S. B., Oleinikov, A. V., Hviid, Lars & Lopez-Perez, Mary, 2019, In: Scientific Reports. 9, 1, 11 p., 6050.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Endemic Burkitt lymphoma - an aggressive childhood cancer linked to Plasmodium falciparum exposure, but not to exposure to other malaria parasites

    Quintana Varon, Maria del Pilar, Smith-Togobo, C., Moormann, A. & Hviid, Lars, 2020, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 128, 2, p. 129-135

    Research output: Contribution to journal › Review › Research › peer-review

  48. Published

    Haptoglobin 1-1 is associated with susceptibility to severe Plasmodium falciparum malaria

    Quaye, I. K., Ekuban, F. A., Goka, B. Q., Adabayeri, V., Kurtzhals, Jørgen, Gyan, B., Ankrah, N. A., Hviid, Lars & Akanmori, B. D., 2000, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 94, 2, p. 216-9 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    The density of knobs on Plasmodium falciparum-infected erythrocytes depends on developmental age and varies among isolates

    Quadt, K. A., Barfod, Lea Klingenberg, Andersen, D., Bruun, J., Gyan, B., Hassenkam, Tue, Ofori, M. F. & Hviid, Lars, 2012, In: P L o S One. 7, 9, p. e45658

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Immunoglobulin M: restrainer of inflammation and mediator of immune evasion by Plasmodium falciparum malaria

    Pleass, R. J., Moore, S. C., Stevenson, L. & Hviid, Lars, Feb 2016, In: Trends in Parasitology. 32, 2, p. 108-119 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

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