Oluf Borbye Pedersen
Visiting professor, Clinical Professor
Pedersen Group
Blegdamsvej 3B, Mærsk Tårnet, 8. sal
2200 København N.
Department of Clinical Medicine
Blegdamsvej 3
2200 København N.
Member of:
Internal medicine: infection medicine
Internal Medicine: Endocrinology
- 2016
- Published
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension
Surendran, P., Drenos, F., Young, R., Warren, H., Cook, J. P., Manning, A. K., Grarup, N., Sim, X., Barnes, D. R., Witkowska, K., Staley, J. R., Tragante, V., Tukiainen, T., Yaghootkar, H., Masca, N., Freitag, D. F., Ferreira, T., Giannakopoulou, O., Tinker, A., Harakalova, M. & 32 others, , 12 Sep 2016, In: Nature Genetics. 48, 10, p. 1151-1161 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic risk scores link body fat distribution with specific cardiometabolic profiles
Svendstrup, M., Sandholt, C. H., Andersson Galijatovic, E. A., Linneberg, Allan René, Jørgensen, T., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Grarup, Niels, Hansen, Torben & drb459, drb459, Aug 2016, In: Obesity. 24, 8, p. 1778-1785 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of a Family-Based Childhood Obesity Treatment Program on Parental Weight Status
Trier, C., Dahl, M., Stjernholm, T., Nielsen, T. R. H., Bøjsøe, C., Fonvig, C. E., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 2016, In: P L o S One. 11, 8, p. 1-11 11 p., e0161921.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional and genetic epidemiological characterisation of the FFAR4 (GPR120) p.R270H variant in the Danish population
Vestmar, M. A., Galijatovic, E. A. A., Christensen, C. R., Pedersen, M. H., Glümer, C., Linneberg, Allan René, Witte, D. R., Jørgensen, M. E., Christensen, C., Brandslund, I., Lauritzen, T., Pedersen, Oluf Borbye, Holst, Birgitte, Grarup, Niels, Schwartz, Thue W. & Hansen, Torben, Sep 2016, In: Journal of Medical Genetics. 53, 9, p. 616-23 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study of the modified Stumvoll Insulin Sensitivity Index identifies BCL2 and FAM19A2 as novel insulin sensitivity loci
Walford, G. A., Gustafsson, S., Rybin, D., Stančáková, A., Chen, H., Liu, C-T., Hong, J., Jensen, R. A., Rice, K., Morris, A. P., Mägi, R., Tönjes, A., Prokopenko, I., Kleber, M. E., Delgado, G., Silbernagel, G., Jackson, A. U., Appel, E. V., Grarup, N., Lewis, J. P. & 59 others, , Oct 2016, In: Diabetes. 65, 10, p. 3200-3211 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Discovery of coding genetic variants influencing diabetes-related serum biomarkers and their impact on risk of type 2 diabetes
Ahluwalia, Tarun Veer Singh, Allin, K. H., Sandholt, C. H., Sparsø, T. H., Jørgensen, M. E., Rowe, M., Christensen, C., Brandslund, I., Lauritzen, T., Linneberg, Allan René, Husemoen, L., Jørgensen, T., Hansen, Torben, Grarup, Niels & Pedersen, Oluf Borbye, Apr 2015, In: The Journal of clinical endocrinology and metabolism. 100, 4, p. E664-71Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MECHANISMS IN ENDOCRINOLOGY: Gut microbiota in patients with type 2 diabetes mellitus
Allin, K. H., Nielsen, T. & Pedersen, Oluf Borbye, 2015, In: European Journal of Endocrinology. 172, 4, p. R167-R177 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The Type 2 Diabetes Risk Allele of TMEM154-rs6813195 Associates with Decreased Beta Cell Function in a Study of 6,486 Danes
Balslev-Harder, M., Appel, E. V. R., Grarup, Niels, Gjesing, A. M. P., Ahluwalia, Tarun Veer Singh, Jørgensen, T., Christensen, C., Brandslund, I., Linneberg, Allan René, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye & Hansen, Torben, 2015, In: PLOS ONE. 10, 3, p. 1-13 13 p., e0120890.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios
Besenbacher, S., Liu, S., Gonzalez-Izarzugaza, J. M., Grove, J., Belling, K. G., Bork-Jensen, J., Huang, S., Als, T. D., Li, S., Yadav, R., Rubio García, A., Lescai, F., Demontis, D., Rao, J., Ye, W., Mailund, T., Møllegaard Friborg, R., Pedersen, C. N. S., Xu, R., Sun, J. & 27 others, , 2015, In: Nature Communications. 6, 9 p., 5969.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fasting serum levels of ferritin are associated with impaired pancreatic beta cell function and decreased insulin sensitivity: a population-based study
Bonfils, L., Ellervik, Christina, Friedrich, N., Linneberg, Allan René, Sandholt, C. H., Jørgensen, M. E., Jørgensen, T., Hansen, Torben, Pedersen, Oluf Borbye & Allin, K. H., 2015, In: Diabetologia. 58, 3, p. 523-533 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary modulation of the gut microbiota - a randomised controlled trial in obese postmenopausal women
Brahe, L. K., Le Chatelier, E., Prifti, E., Pons, N., Kennedy, S., Blædel, T., Håkansson, J., Dalsgaard, T. K., Hansen, Torben, Pedersen, Oluf Borbye, Astrup, A., Ehrlich, S. D. & Larsen, L. H., 2015, In: British Journal of Nutrition. 114, 3, p. 406-417 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Specific gut microbiota features and metabolic markers in postmenopausal women with obesity
Brahe, L. K., Le Chatelier, E., Prifti, E., Pons, N., Kennedy, S., Hansen, Torben, Pedersen, Oluf Borbye, Astrup, A., Ehrlich, S. D. & Larsen, L. H., 15 May 2015, In: Nutrition and Diabetes. 5, 7 p., e159.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants
Dashti, H. S., Follis, J. L., Smith, C. E., Tanaka, T., Cade, B. E., Gottlieb, D. J., Hruby, A., Jacques, P. F., Lamon-Fava, S., Richardson, K., Saxena, R., Scheer, F. A. J. L., Kovanen, L., Bartz, T. M., Perälä, M-M., Jonsson, A. E., Frazier-Wood, A. C., Kalafati, I-P., Mikkilä, V., Partonen, T. & 34 others, , Jan 2015, In: The American Journal of Clinical Nutrition. 101, 1, p. 135-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Response to Comment on Færch et al. GLP-1 Response to Oral Glucose Is Reduced in Prediabetes, Screen-Detected Type 2 Diabetes, and Obesity and Influenced by Sex: The ADDITION-PRO Study. Diabetes 2015;64:2513–2525
Ferch, K., Torekov, Signe Sørensen, Vistisen, D., Johansen, N. B., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Sandbek, A., Holst, Jens Juul & Jørgensen, M. E., 1 Sep 2015, In: Diabetes. 64, 9, p. e30-e31Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
1H-MRS Measured Ectopic Fat in Liver and Muscle in Danish Lean and Obese Children and Adolescents
Fonvig, C. E., Chabanova, E., Andersson, E. A., Ohrt, J. D., Pedersen, Oluf Borbye, Hansen, Torben, Thomsen, Henrik S. & Holm, Jens-Christian, 2015, In: PLOS ONE. 10, 8, 15 p., e0135018.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multidisciplinary care of obese children and adolescents for one year reduces ectopic fat content in liver and skeletal muscle
Fonvig, C. E., Chabanova, E., Ohrt, J. D., Nielsen, L. A., Pedersen, Oluf Borbye, Hansen, Torben, Thomsen, Henrik S. & Holm, Jens-Christian, 2015, In: B M C Pediatrics. 15, p. 1-9 9 p., 196.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota
Forslund, K., Hildebrand, F., Nielsen, T., Falony, G., Le Chatelier, E., Sunagawa, S., Prifti, E., Vieira-Silva, S., Gudmundsdottir, V., Pedersen, H. K., Arumugam, M., Kristiansen, K., Yvonne Voigt, A., Vestergaard, H., Hercog, R., Igor Costea, P., Roat Kultima, J., Li, J., Jørgensen, T., Levenez, F. & 9 others, , 2015, In: Nature. 528, 7581, p. 262-266 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Greenlandic Inuit show genetic signatures of diet and climate adaptation
Fumagalli, M., Moltke, Ida, Grarup, Niels, Racimo, F., Bjerregaard, P., Jørgensen, M. E., Korneliussen, Thorfinn Sand, Gerbault, P., Skotte, L., Linneberg, Allan René, Christensen, C., Brandslund, I., Jørgensen, T., Huerta-Sánchez, E., Schmidt, E. B., Pedersen, Oluf Borbye, Hansen, T., Albrechtsen, Anders & Nielsen, Rasmus, 2015, In: Science (New York, N.Y.). 349, 6254, p. 1343-1347 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-Like Peptide-1 (GLP-1) Response to Oral Glucose is Reduced in Pre-diabetes, Screen-detected Type 2 Diabetes and Obesity, and Influenced by Sex: The ADDITION-PRO Study
Færch, K., Torekov, Signe Sørensen, Vistisen, D., Johansen, N. B., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Sandbæk, A., Holst, Jens Juul & Jørgensen, M. E., Jul 2015, In: Diabetes. 64, p. 2513-25 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
Gaulton, K. J., Ferreira, T., Lee, Y., Raimondo, A., Mägi, R., Reschen, M. E., Mahajan, A., Locke, A., William Rayner, N., Robertson, N., Scott, R. A., Prokopenko, I., Scott, L. J., Green, T., Sparso, T., Thuillier, D., Yengo, L., Grallert, H., Wahl, S., Frånberg, M. & 31 others, , Dec 2015, In: Nature Genetics. 47, 12, p. 1415-25, 3 unpag. pages 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rare genetic variants previously associated with congenital forms of long QT syndrome have little or no effect on the QT interval
Ghouse, Jonas, Have, C. T., Weeke, P., Nielsen, J. B., Ahlberg, G., Balslev-Harder, M., Appel, E. V., Skaaby, T., Olesen, S., Grarup, Niels, Linneberg, Allan René, Pedersen, Oluf Borbye, Haunsø, Stig, Svendsen, Jesper Hastrup, Hansen, Torben, Kanters, Jørgen K. & Salling Olesen, M., 1 Oct 2015, In: European Heart Journal. 36, 37, p. 2523-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic and phenotypic correlations between surrogate measures of insulin release obtained from OGTT data
Gjesing, A. M. P., Ribel-Madsen, R., Harder, M. N., Eiberg, Hans Rudolf Lytchoff, Grarup, Niels, Jørgensen, T., Ekstrøm, Claus Thorn, Pedersen, Oluf Borbye & Hansen, Torben, May 2015, In: Diabetologia. 58, 5, p. 1006-1012 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Splice Region Variant in LDLR Lowers Non-high Density Lipoprotein Cholesterol and Protects against Coronary Artery Disease
Gretarsdottir, S., Helgason, H., Helgadottir, A., Sigurdsson, A., Thorleifsson, G., Magnusdottir, A., Oddsson, A., Steinthorsdottir, V., Rafnar, T., de Graaf, J., Daneshpour, M. S., Hedayati, M., Azizi, F., Grarup, N., Jørgensen, T., Vestergaard, H., Hansen, T., Eyjolfsson, G., Sigurdardottir, O., Olafsson, I. & 8 others, , Sep 2015, In: P L o S Genetics. 11, 9, 20 p., e1005379.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A glycogene mutation map for discovery of diseases of glycosylation
Hansen, Lars, Lind-Thomsen, A., Joshi, Hiren Jitendra, Pedersen, N. B., Have, C. T., Kong, Y., Wang, S., Sparso, T., Grarup, Niels, Vester-Christensen, M. B., Schjoldager, Katrine Ter-Borch Gram, Freeze, H. H., Hansen, Torben, Pedersen, Oluf Borbye, Henrissat, B., Mandel, Ulla, Clausen, Henrik, Wandall, Hans H. & Bennett, Eric Paul, 2015, In: Glycobiology. 25, 2, p. 211-224 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of PTBP1 rs11085226 on glucose-stimulated insulin release in adult Danes
Hansen, T. H., drb459, drb459, Jørgensen, T., Jørgensen, M. E., Lauritzen, T., Brandslund, I., Christensen, C., Pedersen, Oluf Borbye, Hansen, Torben & Gjesing, A. M. P., 20 Mar 2015, In: BMC Medical Genetics. 16, p. 1-9 9 p., 17.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The gut microbiome in cardio-metabolic health
Hansen, T. H., Gøbel, R. J., Hansen, Torben & Pedersen, Oluf Borbye, 2015, In: Genome Medicine. 7, p. 1-16 16 p., 33.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common variants in LEPR, IL6, AMD1, and NAMPT do not associate with risk of juvenile and childhood obesity in Danes: a case-control study
Hollensted, M., Ahluwalia, Tarun Veer Singh, Have, C. T., Grarup, Niels, Fonvig, C. E., Nielsen, T. R. H., Trier, C., Paternoster, L., Pedersen, Oluf Borbye, Holm, Jens-Christian, Sørensen, Thorkild I.A. & Hansen, Torben, 2015, In: BMC Medical Genetics. 16, 9 p., 105.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment with a GLP-1 receptor agonist diminishes the decrease in free plasma leptin during maintenance of weight loss
Iepsen, E. W., Lundgren, J., Dirksen, C., Jensen, J., Pedersen, Oluf Borbye, Hansen, Torben, Madsbad, Sten, Holst, Jens Juul & Torekov, Signe Sørensen, 2015, In: International journal of obesity (2005). 39, 5, p. 834-41 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 receptor agonist treatment increases bone formation and prevents bone loss in weight-reduced obese women
Iepsen, E. P. W., Lundgren, J. R., Hartmann, Bolette, Pedersen, Oluf Borbye, Hansen, Torben, Jørgensen, Niklas Rye, Jensen, J. B., Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2015, In: The Journal of clinical endocrinology and metabolism. 100, 8, p. 2909 –2917 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interactions of Lipid Genetic Risk Scores with Estimates of Metabolic Health in a Danish Population
Justesen, Johanne Marie, Allin, K. H., Sandholt, C. H., Borglykke, A., Krarup, N. T., Grarup, Niels, Linneberg, Allan René, Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 24 Feb 2015, In: Circulation. Cardiovascular genetics. 8, p. 465-72 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation
Kato, N., Loh, M., Takeuchi, F., Verweij, N., Wang, X., Zhang, W., Kelly, T. N., Saleheen, D., Lehne, B., Mateo Leach, I., Drong, A. W., Abbott, J., Wahl, S., Tan, S-T., Scott, W. R., Campanella, G., Chadeau-Hyam, M., Afzal, U., Ahluwalia, T. V. S., Bonder, M. J. & 31 others, , 2015, In: Nature Genetics. 47, 11, p. 1282-93 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intake of macro- and micronutrients in Danish vegans
Kristensen, N. B., Madsen, M. L., Hansen, T. H., Allin, K. H., Hoppe, C., Fagt, S., Lausten, M. S., Gøbel, R. J., drb459, drb459, Hansen, Torben & Pedersen, Oluf Borbye, 30 Oct 2015, In: Nutrition Journal. 14, 1, p. 1-10 10 p., 115.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reference values for serum total adiponectin in healthy non-obese children and adolescents
Lausten-Thomsen, U., Christiansen, M., Fonvig, C. E., Trier, C., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 23 Oct 2015, In: Clinica Chimica Acta. 450, p. 11-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Asthma in patients with psoriasis
Lønnberg, A. S., Skov, L., Skytthe, A., Kyvik, K. O., Pedersen, Oluf Borbye, Meteran, Howraman, Backer, Vibeke & Thomsen, Simon Francis, 2015, In: British Journal of Dermatology. p. 1660-1661Research output: Contribution to journal › Letter › Research › peer-review
- Published
Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus
Mahajan, A., Sim, X., Ng, H. J., Manning, A., Rivas, M. A., Highland, H. M., Locke, A. E., Grarup, N., Im, H. K., Cingolani, P., Flannick, J., Fontanillas, P., Fuchsberger, C., Gaulton, K. J., Teslovich, T. M., Rayner, N. W., Robertson, N. R., Beer, N. L., Rundle, J. K., Bork-Jensen, J. & 31 others, , Jan 2015, In: P L o S Genetics. 11, 1, p. 1-25 25 p., e1004876.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Antibiotics on Gut Microbiota, Gut Hormones and Glucose Metabolism
Mikkelsen, K. H., Frost, M., Bahl, M. I., Licht, T. R., Jensen, U. S., Rosenberg, Jacob, Pedersen, Oluf Borbye, Hansen, Torben, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, 12 Nov 2015, In: PLOS ONE. 10, 11, p. 1-14 e0142352.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Uncovering the genetic history of the present-day greenlandic population
Moltke, Ida, Fumagalli, M., Korneliussen, Thorfinn Sand, Crawford, J. E., Bjerregaard, P., Jørgensen, M. E., Grarup, Niels, Gulløv, H. C., Linneberg, Allan René, Pedersen, Oluf Borbye, Hansen, Torben, Nielsen, Rasmus & Albrechtsen, Anders, 2015, In: American Journal of Human Genetics. 96, 1, p. 54-69 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prenatal exposure to systemic antibacterials and overweight and obesity in Danish schoolchildren: a prevalence study
Mor, A., Antonsen, S., Kahlert, J., Holsteen, V., Jørgensen, S., Holm-Pedersen, J., Sørensen, H. T., Pedersen, Oluf Borbye & Ehrenstein, V., 2015, In: International journal of obesity (2005). 39, 10, p. 1450-1455 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin resistance as a physiological defense against metabolic stress: implications for the management of subsets of type 2 diabetes
Nolan, C. J., Ruderman, N. B., Kahn, S. E., Pedersen, Oluf Borbye & Prentki, M., Mar 2015, In: Diabetes. 64, 3, p. 673-86 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Response to Comments on Nolan et al. Insulin Resistance as a Physiological Defense Against Metabolic Stress: Implications for the Management of Subsets of Type 2 Diabetes. Diabetes 2015;64:673-686
Nolan, C. J., Ruderman, N. B., Kahn, S. E., Pedersen, Oluf Borbye & Prentki, M., 2015, In: Diabetes. 64, 10, p. e38-9 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Comparative analyses of QTLs influencing obesity and metabolic phenotypes in pigs and humans
Pant, S. D., Karlskov-Mortensen, Peter, Jacobsen, M. J., Cirera, Susanna, Kogelman, L., Bruun, Camilla Vibeke Sichlau, Mark, T., Jørgensen, Claus Bøttcher, Grarup, Niels, Appel, E. V. R., Galjatovic, E. A. A., Hansen, T., Pedersen, Oluf Borbye, Guerin, M., Huby, T., Lesnik, P., Meuwissen, T. H. E., Kadarmideen, H. & Fredholm, Merete, 8 Sep 2015, In: PLOS ONE. 10, 9, 22 p., e0137356.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood
Rönn, T., Volkov, P., Gillberg, L., Kokosar, M., Perfilyev, A., Jacobsen, A. L., Jørgensen, S. W., Brøns, C., Jansson, P., Eriksson, K., Pedersen, Oluf Borbye, Hansen, Torben, Groop, L., Stener-Victorin, E., Vaag, Allan, Nilsson, E. & Ling, C., 1 Jul 2015, In: Human Molecular Genetics. 24, 13, p. 3792-813 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association studies of human adiposity: Zooming in on synapses.
Sandholt, C. H., Grarup, Niels, Pedersen, Oluf Borbye & Hansen, Torben, 2015, In: Molecular and Cellular Endocrinology. 418, Part 2, p. 90-100 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Obesity Beige adipocytes-will they beat obesity?.
Sandholt, C. H. & Pedersen, Oluf Borbye, 2015, In: Nature Reviews Endocrinology. 11, 12, p. 694-696 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced CD300LG mRNA tissue expression, increased intramyocellular lipid content and impaired glucose metabolism in healthy male carriers of Arg82Cys in CD300LG: a novel genometabolic cross-link between CD300LG and common metabolic phenotypes
Støy, J., Kampmann, U., Mengel, A., Magnusson, N. E., Jessen, N., Grarup, Niels, Rungby, Jørgen, Stødkilde-Jørgensen, H., Brandslund, I., Christensen, C., Hansen, Torben, Pedersen, Oluf Borbye & Møller, N., 2015, In: BMJ open diabetes research & care. 3, 1, p. 1-12 12 p., e000095.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations of the Inflammatory Marker YKL-40 with Measures of Obesity and Dyslipidaemia in Individuals at High Risk of Type 2 Diabetes
Thomsen, S. B., Gjesing, A. M. P., Rathcke, C. N., Ekstrøm, Claus Thorn, Eiberg, Hans Rudolf Lytchoff, Hansen, T., Pedersen, Oluf Borbye & drb459, drb459, 21 Jul 2015, In: PLOS ONE. 10, 7, p. 1-10 10 p., e0133672.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility
Wessel, J., Chu, A. Y., Willems, S. M., Wang, S., Yaghootkar, H., Brody, J. A., Dauriz, M., Hivert, M-F., Raghavan, S., Lipovich, L., Hidalgo, B., Fox, K., Huffman, J. E., An, P., Lu, Y., Rasmussen-Torvik, L. J., Grarup, N., Ehm, M. G., Li, L., Baldridge, A. S. & 31 others, , 29 Jan 2015, In: Nature Communications. 6, p. 5897Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
Winkler, T. W., Justice, A. E., Graff, M., Barata, L., Feitosa, M. F., Chu, S., Czajkowski, J., Esko, T., Fall, T., Kilpeläinen, T. O., Lu, Y., Mägi, R., Mihailov, E., Pers, T. H., Rüeger, S., Teumer, A., Ehret, G. B., Ferreira, T., Heard-Costa, N. L., Karjalainen, J. & 31 others, , 1 Oct 2015, In: P L o S Genetics. 11, 10, p. 1-42 42 p., e1005378.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association analysis of 29,956 individuals confirms that a low-frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion
Yaghootkar, H., Stancáková, A., Freathy, R. M., Vangipurapu, J., Weedon, M. N., Xie, W., Wood, A. R., Ferrannini, E., Mari, A., Ring, S. M., Lawlor, D. A., Davey Smith, G., Jørgensen, T., Hansen, T., Pedersen, O., Steinthorsdottir, V., Guðbjartsson, D. F., Thorleifsson, G., Thorsteinsdottir, U., Stefansson, K. & 7 others, , Jun 2015, In: Diabetes. 64, 6, p. 2279-85 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial incretin and islet hormone responses and dipeptidyl-peptidase 4 enzymatic activity in patients with maturity onset diabetes of the young
Østoft, S. H., Bagger, J. I., Hansen, Torben, Hartmann, Bolette, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 1 Aug 2015, In: European Journal of Endocrinology. 173, 2, p. 205-215 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Genomet og diabetes
Allin, K. H., Hansen, Torben & Pedersen, Oluf Borbye, 10 Nov 2014, In: Ugeskrift for Laeger. 176, 23, p. 2176-2179 V06140337.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction between genetic predisposition to adiposity and dietary protein in relation to subsequent change in body weight and waist circumference
Ankarfeldt, Mikkel Zöllner, Larsen, S. C., Ängquist, Lars, Husemoen, L. L. N., Roswall, N., Overvad, K., Jakobsen, M. U., Halkjær, J., Tjønneland, A., Linneberg, Allan René, Toft, Ulla Marie Nørgaard, Hansen, Torben, Pedersen, Oluf Borbye, Heitmann, Berit, Astrup, A. & Sørensen, Thorkild I.A., 2014, In: P L o S One. 9, 10, 10 p., e110890.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary intervention modulates the gut microbiota and improves insulin resistance - a randomized controlled trial in obese postmenopausal women
Brahe, L. K., Le Chatelier, E., Prifti, E., Kennedy, S., Blædel, T., Håkansson, J., Pedersen, Oluf Borbye, Astrup, A., Ehrlich, S. & Larsen, L. H., 2014, In: Obesity Reviews. 15, Suppl. 2, p. 41-42 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Lessons from whole-exome sequencing in MODYX families
Dusatkova, P., Fang, M., Pruhova, S., Gjesing, A. P., Cinek, O., Hansen, Torben, Pedersen, Oluf Borbye, Xu, X. & Lebl, J., Jun 2014, In: Diabetes Research and Clinical Practice. 104, 3, p. e72-4 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss-of-function mutations in SLC30A8 protect against type 2 diabetes
Flannick, J., Thorleifsson, G., Beer, N. L., Jacobs, S. B. R., Grarup, N., Burtt, N. P., Mahajan, A., Fuchsberger, C., Atzmon, G., Benediktsson, R., Blangero, J., Bowden, D. W., Brandslund, I., Brosnan, J., Burslem, F., Chambers, J., Cho, Y. S., Christensen, C., Douglas, D. A., Duggirala, R. & 31 others, , Apr 2014, In: Nature Genetics. 46, 4, p. 357-63 7 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Tarmbakterier kan have betydning for overvægt i barnealderen
Fonvig, C. E., Pihl, A. F., Hansen, Torben, Pedersen, Oluf Borbye & Holm, Jens-Christian, 18 Aug 2014, In: Ugeskrift for Laeger. 176, p. 2-6 5 p., V03140171.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of a target region capture sequencing platform using monogenic diabetes as a study-model
Gao, R., Liu, Y., Gjesing, A. M. P., Hollensted, M., Wan, X., He, S., Pedersen, Oluf Borbye, Yi, X., Wang, J. & Hansen, Torben, 2014, In: B M C Genetics. 15, 9 p., 13.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High heritability and genetic correlation of intravenous glucose- and tolbutamide-induced insulin secretion among non-diabetic family members of type 2 diabetic patients
Gjesing, A. M. P., Hornbak, M., Allin, K. H., Ekstrøm, Claus Thorn, Urhammer, Søren Asger, Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye & Hansen, Torben, Jun 2014, In: Diabetologia. 57, 6, p. 1173-1181 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic susceptibility to type 2 diabetes and obesity: from genome-wide association studies to rare variants and beyond
Grarup, Niels, Sandholt, C. H., Hansen, Torben & Pedersen, Oluf Borbye, Aug 2014, In: Diabetologia. 57, 8, p. 1528-41 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and Type 2 diabetes susceptibility
Guigas, B., de Leeuw van Weenen, J. E., van Leeuwen, N., Simonis-Bik, A. M., van Haeften, T. W., Nijpels, G., Houwing-Duistermaat, J. J., Beekman, M., Deelen, J., Havekes, L. M., Penninx, B. W. J. H., Vogelzangs, N., van 't Riet, E., Dehghan, A., Hofman, A., Witteman, J. C., Uitterlinden, A. G., Grarup, N., Jørgensen, T., Witte, D. R. & 15 others, , Aug 2014, In: Diabetic Medicine. 31, 8, p. 1001-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A combined analysis of 48 type 2 diabetes genetic risk variants shows no discriminative value to predict time to first prescription of a glucose lowering drug in Danish patients with screen detected type 2 diabetes.
Hornbak, M., Allin, K. H., Jensen, M. L., Lau, C. J., Witte, D. R., Jørgensen, M. E., Sandbæk, A., Lauritzen, T., Andersson, Åsa, Pedersen, Oluf Borbye & Hansen, Torben, 2014, In: PloS One. 9, 8, 10 p., e104837.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MTHFR C677T genotype and cardiovascular risk in a general population without mandatory folic acid fortification
Husemoen, L. L. N., Skaaby, T., Jørgensen, T., Thuesen, B. H., Fenger, M., Grarup, Niels, Sandholt, C. H., Hansen, Torben, Pedersen, Oluf Borbye & Linneberg, Allan René, 24 Jan 2014, In: European Journal of Nutrition. 53, 7, p. 1549-59 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two randomized cross-over trials assessing the impact of dietary gluten or wholegrain on the gut microbiome and host metabolic health
Ibrügger, S., Gøbel, R. J., drb459, drb459, Licht, T. R., Frøkiær, Hanne, Linneberg, Allan René, Hansen, Torben, Gupta, R., Pedersen, Oluf Borbye, Kristensen, M. B. & Lauritzen, Lotte, 2014, In: Journal of Clinical Trials. 4, 4, 9 p., 1000178.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium: Diabetologia
Koivula, R., Heggie, A., Barnett, A., Cederberg, H., Hansen, T. H., Koopman, A., Ridderstråle, M., Rutters, F., Vestergaard, H., Gupta, R., Herrgård, S., Heymans, M., Perry, M., Rauh, S., Siloaho, M., Teare, H. A., Thorand, B., Bell, J., Brunak, S., Frost, G. & 13 others, , 2014, In: Diabetologia. 57, 6, p. 1-11 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pleiotropic genes for metabolic syndrome and inflammation
Kraja, A. T., Chasman, D. I., North, K. E., Reiner, A. P., Yanek, L. R., Oskari Kilpeläinen, T., Smith, J. A., Dehghan, A., Dupuis, J., Johnson, A. D., Feitosa, M. F., Tekola-Ayele, F., Chu, A. Y., Nolte, I. M., Dastani, Z., Morris, A., Pendergrass, S. A., Sun, Y. V., Ritchie, M. D., Vaez, A. & 31 others, , 2014, In: Molecular Genetics and Metabolism. 112, 4, p. 317-38 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study
Langenberg, C., Sharp, S. J., Franks, P. W., Scott, R. A., Deloukas, P., Forouhi, N. G., Froguel, P., Groop, L. C., Hansen, T., Palla, L., Pedersen, O., Schulze, M. B., Tormo, M-J., Wheeler, E., Agnoli, C., Arriola, L., Barricarte, A., Boeing, H., Clarke, G. M., Clavel-Chapelon, F. & 27 others, , 2014, In: P L o S Medicine (Print). 11, 5, 14 p., e1001647.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary ascorbic acid and subsequent change in body weight and waist circumference: associations may depend on genetic predisposition to obesity - a prospective study of three independent cohorts
Larsen, S. C., Ängquist, Lars, Ahluwalia, Tarun Veer Singh, Skaaby, T., Roswall, N., Tjønneland, A., Halkjær, J., Overvad, K., Pedersen, Oluf Borbye, Hansen, Torben, Linneberg, Allan René, Husemoen, L. L. N., Toft, Ulla Marie Nørgaard, Heitmann, B. L. & Sørensen, Thorkild I.A., 2014, In: Nutrition Journal. 13, p. 1-11 11 p., 43.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction between genetic predisposition to obesity and dietary calcium in relation to subsequent change in body weight and waist circumference
Larsen, S. C., Ängquist, Lars, Ahluwalia, Tarun Veer Singh, Skaaby, T., Roswall, N., Tjønneland, A., Halkjær, J., Overvad, K., Pedersen, Oluf Borbye, Hansen, Torben, Linneberg, Allan René, Husemoen, L. L. N., Toft, Ulla Marie Nørgaard, Heitmann, Berit & Sørensen, Thorkild I.A., Apr 2014, In: The American Journal of Clinical Nutrition. 99, 4Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An integrated catalog of reference genes in the human gut microbiome
Li, J., Jia, H., Cai, X., Zhong, H., Feng, Q., Sunagawa, S., Arumugam, M., Kultima, J. R., Prifti, E., Nielsen, T., Juncker, A., Manichanh, C., Chen, B., Zhang, W., Levenez, F., Wang, J., Xu, X., Xiao, L., Liang, S., Zhang, D. & 17 others, , 2014, In: Nature Biotechnology. 32, 8, p. 834-845 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population
Li, S., Besenbacher, S., Li, Y., Kristiansen, Karsten, Grarup, Niels, Albrechtsen, Anders, Sparsø, T. H., Korneliussen, Thorfinn Sand, Hansen, Torben, Wang, J., Nielsen, Rasmus, Pedersen, Oluf Borbye, Bolund, L. & Schierup, M. H., 2014, In: European Journal of Human Genetics. 22, p. 1040-1045 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes
Moltke, I., Grarup, N., Jørgensen, M. E., Bjerregaard, P., Treebak, J. T., Fumagalli, M., Korneliussen, T. S., Andersen, M. A., Nielsen, T. S., Krarup, N. T., Gjesing, A. M. P., Zierath, J. R., Linneberg, A., Wu, X., Sun, G., Jin, X., Al-Aama, J., Wang, J., Borch-Johnsen, K., Pedersen, O. & 3 others, , 2014, In: Nature. 512, 7513, p. 190-193 4 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes
Nielsen, H. B., Almeida, M., Juncker, A., Rasmussen, S., Li, J., Sunagawa, S., Plichta, D. R., Gautier, L., Pedersen, A. G., Le Chatelier, E., Pelletier, E., Bonde, I., Nielsen, T., Manichanh, C., Arumugam, M., Batto, J-M., dos Santos, M. B. Q., Blom, N., Borruel, N., Burgdorf, K. S. & 31 others, , 2014, In: Nature Biotechnology. 32, 8, p. 822–828 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-Lowering Effects and Low Risk of Hypoglycemia in Patients With Maturity-Onset Diabetes of the Young When Treated With a GLP-1 Receptor Agonist: A Double-Blind, Randomized, Crossover Trial
Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Faber, Jens, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 14 Jun 2014, In: Diabetes Care. 37, 7, p. 1797-1805 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin Effect and Glucagon Responses to Oral and Intravenous Glucose in Patients with Maturity Onset Diabetes of the Young - Type 2 and Type 3
Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 27 Mar 2014, In: Diabetes. 63, 8, p. 2838-44 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals
Qi, Q., Oskari Kilpeläinen, T., Downer, M. K., Tanaka, T., Smith, C. E., Sluijs, I., Sonestedt, E., Chu, A. Y., Renström, F., Lin, X., Angquist, L. H., Huang, J., Liu, Z., Li, Y., Asif Ali, M., Xu, M., Ahluwalia, T. V. S., Boer, J. M. A., Chen, P., Daimon, M. & 89 others, , 7 Aug 2014, In: Human Molecular Genetics. 23, 25, p. 6961-6972 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes
Steinthorsdottir, V., Thorleifsson, G., Sulem, P., Helgason, H., Grarup, N., Sigurdsson, A., Helgadottir, H. T., Johannsdottir, H., Magnusson, O. T., Gudjonsson, S. A., Justesen, J. M., Harder, M. N., Jørgensen, M. E., Christensen, C., Brandslund, I., Sandbæk, A., Lauritzen, T., Vestergaard, H., Linneberg, A., Jørgensen, T. & 14 others, , 26 Jan 2014, In: Nature Genetics. 46, 3, p. 294-300 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Blood pressure levels in male carriers of Arg82Cys in CD300LG
Støy, J., Grarup, Niels, Hørlyck, A., Ibsen, L., Rungby, J., Poulsen, P. L., Brandslund, I., Christensen, C., Hansen, Torben, Pedersen, Oluf Borbye, Møller, N. & Kampmann, U., 2014, In: PLOS ONE. 9, 10, 6 p., e109646.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KCNQ1 Long QT syndrome patients have hyperinsulinemia and symptomatic hypoglycemia
Torekov, Signe Sørensen, Iepsen, E., Christiansen, M., Linneberg, Allan René, Pedersen, Oluf Borbye, Holst, Jens Juul, Kanters, Jørgen K. & Hansen, Torben, Apr 2014, In: Diabetes. 63, 4, p. 1315-1325 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A functional amino acid substitution in the glucose-dependent insulinotropic polypeptide receptor (GIPR) gene is associated with lower bone mineral density and increased fracture risk
Torekov, Signe Sørensen, Harsløf, T., Rejnmark, L., Eiken, P., Jensen, Jens-Erik Beck, Herman, A. P., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul & Langdahl, B. L., Apr 2014, In: The Journal of clinical endocrinology and metabolism. 99, 4, p. E729-33 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway
't Hart, L. M., Fritsche, A., Nijpels, G., van Leeuwen, N., Donnelly, L. A., Dekker, J. M., Alssema, M., Fadista, J., Carlotti, F., Gjesing, A. P., Palmer, C. N. A., van Haeften, T. W., Herzberg-Schäfer, S. A., Simonis-Bik, A. M. C., Houwing-Duistermaat, J. J., Helmer, Q., Deelen, J., Guigas, B., Hansen, T., Machicao, F. & 14 others, , 14 May 2013, In: Diabetes. 62, 9, p. 3275-3281 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene x Physical Activity Interactions in Obesity: Combined Analysis of 111,421 Individuals of European Ancestry
Ahmad, S., Rukh, G., Varga, T. V., Ali, A., Kurbasic, A., Shungin, D., Ericson, U., Koivula, R. W., Chu, A. Y., Rose, L. M., Ganna, A., Qi, Q., Stancakova, A., Sandholt, C. H., Elks, C. E., Curhan, G., Jensen, M. K., Tamimi, R. M., Allin, K. H., Jorgensen, T. & 26 others, , Jul 2013, In: PLOS Genetics. 9, 7Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry
Ahmad, S., Rukh, G., Varga, T. V., Ali, A., Kurbasic, A., Shungin, D., Ericson, U., Koivula, R. W., Chu, A. Y., Rose, L. M., Ganna, A., Qi, Q., Stančáková, A., Sandholt, C. H., Elks, C. E., Curhan, G., Jensen, M. K., Tamimi, R. M., Allin, K. H., Jørgensen, T. & 27 others, , Jul 2013, In: P L o S Genetics (Online). 9, 7, p. e1003607Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes
Albrechtsen, A., Grarup, N., Li, Y., Sparsø, T. H., Tian, G., Cao, H., Jiang, T., Kim, S. Y., Korneliussen, T. S., Li, Q., Nie, C., Wu, R., Skotte, L., Morris, A. P., Ladenvall, C., Cauchi, S., Stancáková, A., Andersen, G., Astrup, A., Banasik, K. & 86 others, , 2013, In: Diabetologia. 56, 2, p. 298-310 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reassessment of the putative role of BLK-p.A71T loss-of-function mutation in MODY and type 2 diabetes
Bonnefond, A., Yengo, L., Philippe, J., Dechaume, A., Ezzidi, I., Vaillant, E., Gjesing, A. P., Andersson, E. A., Czernichow, S., Hercberg, S., Hadjadj, S., Charpentier, G., Lantieri, O., Balkau, B., Marre, M., Pedersen, Oluf Borbye, Hansen, Torben, Froguel, P. & Vaxillaire, M., Mar 2013, In: Diabetologia. 56, 3, p. 492-496 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
What is the contribution of two genetic variants regulating VEGF levels to type 2 diabetes risk and to microvascular complications?
Bonnefond, A., Saulnier, P., Stathopoulou, M. G., Grarup, Niels, Ndiaye, N. C., Roussel, R., Nezhad, M. A., Dechaume, A., Lantieri, O., Hercberg, S., Lauritzen, T., Balkau, B., El-Sayed Moustafa, J. S., Hansen, Torben, Pedersen, Oluf Borbye, Froguel, P., Charpentier, G., Marre, M., Hadjadj, S. & Visvikis-Siest, S., Feb 2013, In: P L o S One. 8, 2, p. e55921Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Correction: Genetic Variant SCL2A2 Is Associated with Risk of Cardiovascular Disease - Assessing the Individual and Cumulative Effect of 46 Type 2 Diabetes Related Genetic Variants
Borglykke, A., Grarup, N., Sparsø, T. H., Linneberg, Allan René, Fenger, M., Jeppesen, J., Hansen, Torben, Pedersen, Oluf Borbye & Jørgensen, T., 2013, In: P L o S One. 8, 5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity
Dimas, A. S., Lagou, V., Barker, A., Knowles, J. W., Mägi, R., Hivert, M-F., Benazzo, A., Rybin, D., Jackson, A. U., Stringham, H. M., Song, C., Fischer-Rosinsky, A., Boesgaard, T. W., Grarup, N., Abbasi, F. A., Assimes, T. L., Hao, K., Yang, X., Lecoeur, C., Barroso, I. & 31 others, , 2 Dec 2013, In: Diabetes. 63, 6, p. 2158-2171 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic risk score of 46 type 2 diabetes risk variants associates with changes in plasma glucose and estimates of pancreatic beta-cell function over 5 years of follow-up
Galijatovic, E. A. A., Allin, K. H., Sandholt, C. H., Borglykke, A., Lau, C. J., Ribel-Madsen, R., Sparsø, T., Justesen, Johanne Marie, Harder, M. N., Jørgensen, M. E., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 8 Jul 2013, In: Diabetes. 62, 10, p. 3610 3617 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does DNA Methylation of PPARGC1A Influence Insulin Action in First Degree Relatives of Patients with Type 2 Diabetes?
Gillberg, L., Jacobsen, S., Ribel-Madsen, R., Gjesing, A. M. P., Boesgaard, T. W., Ling, C., Pedersen, Oluf Borbye, Hansen, Torben & Vaag, Allan, 2013, In: P L o S One. 8, 3, p. e58384Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
Grarup, N., Sulem, P., Sandholt, C. H., Thorleifsson, G., Ahluwalia, T. V. S., Steinthorsdottir, V., Bjarnason, H., Gudbjartsson, D. F., Magnusson, O. T., Sparsø, T., Albrechtsen, A., Kong, A., Masson, G., Tian, G., Cao, H., Nie, C., Kristiansen, K., Husemoen, L. L., Thuesen, B., Li, Y. & 10 others, , 2013, In: P L o S Genetics. 9, 6, 12 p., e1003530.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Type 2 Diabetes Risk Alleles Near BCAR1 and in ANK1 Associate With Decreased ß-Cell Function Whereas Risk Alleles Near ANKRD55 and GRB14 Associate With Decreased Insulin Sensitivity in the Danish Inter99 Cohort
Harder, M. N., Ribel-Madsen, R., Justesen, Johanne Marie, Sparsø, T., Galijatovic, E. A. A., Grarup, Niels, Jørgensen, T., Linneberg, Allan René, Hansen, Torben & Pedersen, Oluf Borbye, 1 Apr 2013, In: Journal of Clinical Endocrinology and Metabolism. 98, 4, p. 801-806Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism
Horikoshi, M., Yaghootkar, H., Mook-Kanamori, D. O., Sovio, U., Taal, H. R., Hennig, B. J., Bradfield, J. P., St Pourcain, B., Evans, D. M., Charoen, P., Kaakinen, M., Cousminer, D. L., Lehtimäki, T., Kreiner-Møller, E., Warrington, N. M., Bustamante, M., Feenstra, B., Berry, D. J., Thiering, E., Pfab, T. & 31 others, , 2013, In: Nature Genetics. 45, 1, p. 76-82 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chronic family stress moderates the association between a TOMM40 variant and triglyceride levels in two independent Caucasian samples
Jiang, R., Brummett, B. H., Hauser, E. R., Babyak, M. A., Siegler, I. C., Singh, A., Astrup, A., Pedersen, Oluf Borbye, Hansen, T., Holst, C., Sørensen, Thorkild I.A. & Williams, R. B., 2013, In: Biological Psychology. 93, 1, p. 184-189 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin Resistance and Impaired Pancreatic β-Cell Function in Adult Offspring of Women With Diabetes in Pregnancy
Kelstrup, L., Damm, Peter, Mathiesen, Elisabeth, Hansen, Torben, Vaag, Allan, Pedersen, Oluf Borbye & Clausen, Tine Dalsgaard, 2013, In: The Journal of clinical endocrinology and metabolism. 98, 9, p. 3793-3801 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin resistance and impaired pancreatic beta-cell function in adult offspring of women with diabetes in pregnancy
Kelstrup, L., Damm, Peter, Mathiesen, Elisabeth, Hansen, Torben, Vaag, Allan, Pedersen, Oluf Borbye & Clausen, Tine Dalsgaard, 24 Jun 2013, In: The Journal of clinical endocrinology and metabolism. 98, 9, p. 3793-3801 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Richness of human gut microbiome correlates with metabolic markers
Le Chatelier, E., Nielsen, T., Qin, J., Prifti, E., Hildebrand, F., Falony, G., Almeida, M., Arumugam, M., Batto, J-M., Kennedy, S., Leonard, P., Li, J., Burgdorf, K. S., Grarup, N., Jørgensen, T., Brandslund, I., Nielsen, H. B., Juncker, A., dos Santos, M. B. Q., Levenez, F. & 62 others, , 2013, In: Nature. 500, 7464, p. 541-546 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes
Lohmueller, K. E., Sparsø, T. H., Li, Q., Galijatovic, E. A. A., Korneliussen, T. S., Albrechtsen, A., Banasik, K., Grarup, N., Hallgrimsdottir, I., Kiil, K., Oskari Kilpeläinen, T., Krarup, N. T., Pers, T. H., Sanchez, G., Hu, Y., DeGiorgio, M., Jørgensen, T., Sandbæk, A., Lauritzen, T., Brunak, S. & 6 others, , 5 Dec 2013, In: American Journal of Human Genetics. 93, 6, p. 1072-1086 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gut microbiota may have influence on glucose and lipid metabolism.
Mikkelsen, K. H., Nielsen, M. F., Tvede, M., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, 11 Nov 2013, In: Ugeskrift for Laeger. 175, 46, p. 2785-2788 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Long-term renal outcome in the Steno 2 study
Ollgaard, J., Persson, F., Rossing, P., Parving, H., Pedersen, Oluf Borbye & Gaede, P. H., 2013, In: Diabetologia. 56, p. S45-S46Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of GWAS identified BMI loci on changes in body weight among middle-aged danes during a five year period
Sandholt, C. H., Allin, K. H., Toft, U., Borglykke, A., Ribel-Madsen, R., Sparsø, T. H., Justesen, Johanne Marie, Harder, M. N., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 26 Jun 2013, In: Obesity. 22, 3, p. 901-908 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 919113
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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5238
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
Research output: Contribution to journal › Journal article › Research › peer-review
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4522
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
Research output: Contribution to journal › Journal article › Research › peer-review
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