Jørgen Rungby
Clinical Associate Professor, Clinical Professor
Department of Clinical Medicine
Niels Steensens Vej 2-4, 2820 Gentofte
Member of:
Internal Medicine: Endocrinology
- Published
14-fold increased prevalence of rare glucokinase gene variant carriers in unselected Danish patients with newly diagnosed type 2 diabetes
Gjesing, A. P., Engelbrechtsen, L., Cathrine B. Thuesen, A., Have, C. T., Hollensted, M., Grarup, N., Linneberg, A., Steen Nielsen, J., Christensen, L. B., Thomsen, R. W., Johansson, K. E., Cagiada, M., Gersing, S., Hartmann-Petersen, R., Lindorff-Larsen, K., Vaag, A., Sørensen, H. T., Brandslund, I., Beck-Nielsen, H., Pedersen, O. & 2 others, , 2022, In: Diabetes Research and Clinical Practice. 194, 9 p., 110159.Research output: Contribution to journal › Journal article › Research › peer-review
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A single dose of exenatide had no effect on blood flow velocity in the middle cerebral artery in elderly healthy volunteers: Randomized, placebo-controlled, double-blind clinical trial
Ölmestig, J., Marlet, I. R., Vilsbøll, Tina, Rungby, Jørgen, Rostrup, Egill, Lambertsen, K. L. & Kruuse, Christina Rostrup, 2022, In: Frontiers in Aging Neuroscience. 14, 10 p., 899389.Research output: Contribution to journal › Journal article › Research › peer-review
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Acute loading has minor influence on human articular cartilage gene expression and glycosaminoglycan composition in late-stage knee osteoarthritis: a randomised controlled trial
Jørgensen, A. E. M., Schjerling, Peter, DellaValle, B., Rungby, Jørgen & Kjær, Michael, 2023, In: Osteoarthritis and Cartilage. 31, 7, p. 884-893 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antidiabetic medication and risk of dementia in patients with type 2 diabetes: a nested case control study
Wium-Andersen, I. K., Osler, Merete, Jørgensen, Martin Balslev, Rungby, Jørgen & Wium-Andersen, M. K., 2019, In: European Journal of Endocrinology. 181, 5, p. 499-507 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of parental history of type 2 diabetes with age, lifestyle, anthropometric factors, and clinical severity at type 2 diabetes diagnosis: results from the DD2 study
Svensson, E., Berencsi, K., Sander, S., Mor, A., Rungby, Jørgen, Nielsen, J. S., Friborg, S., Brandslund, I., Christiansen, J. S., Vaag, Allan, Beck-Nielsen, H., Sørensen, H. T. & Thomsen, R. W., Mar 2016, In: Diabetes/Metabolism Research and Reviews. 32, 3, p. 308-15 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Blood-Brain Glucose Transfer in Alzheimer's disease: Effect of GLP-1 Analog Treatment
Gejl, M., Brock, Birgitte, Egefjord, L., Vang, K., Rungby, Jørgen & Gjedde, Albert, Dec 2017, In: Scientific Reports. 7, 1, 10 p., 17490.Research output: Contribution to journal › Journal article › Research › peer-review
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Blood-brain barrier pathology in patients with severe mental disorders: a systematic review and meta-analysis of biomarkers in case-control studies
Futtrup, J., Margolinsky, R., Benros, Michael Eriksen, Moos, T., Routhe, L. J., Rungby, Jørgen & Krogh, Jesper, Jul 2020, In: Brain, behavior, & immunity - health. 6, 9 p., 100102.Research output: Contribution to journal › Journal article › Research › peer-review
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Bone resorption is unchanged by liraglutide in type 2 diabetes patients: A randomised controlled trial
Hygum, K., Harsløf, T., Jørgensen, Niklas Rye, Rungby, Jørgen, Pedersen, S. B. & Langdahl, B. L., 2020, In: Bone. 132, 9 p., 115197.Research output: Contribution to journal › Journal article › Research › peer-review
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Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology
Rydbirk, R., Østergaard, O., Folke, J., Hempel, C., DellaValle, B., Andresen, T. L., Løkkegaard, A., Hejl, A-M., Bode, M., Blaabjerg, M., Møller, M., Danielsen, E. H., Salvesen, L., Starhof, C. C., Bech, S., Winge, K., Rungby, J., Pakkenberg, B., Brudek, T., Olsen, J. V. & 1 others, , 2022, In: Cellular and Molecular Life Sciences. 79, 6, 22 p., 336.Research output: Contribution to journal › Journal article › Research › peer-review
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CRP, C-Peptide, and Risk of First-Time Cardiovascular Events and Mortality in Early Type 2 Diabetes: A Danish Cohort Study
Gedebjerg, A., Bjerre, M., Kjaergaard, A. D., Nielsen, J. S., Rungby, Jørgen, Brandslund, I., Maeng, M., Beck-Nielsen, H., Vaag, A., Sørensen, H. T., Hansen, T. K. & Thomsen, R. W., 2023, In: Diabetes Care. 46, 5, p. 1037-1045 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characteristics influencing expected cognitive performance during hypoglycaemia in type 2 diabetes
Petersen, J. Z., Nilsson, M., Rungby, Jørgen & Miskowiak, Kamilla, 2019, In: Psychoneuroendocrinology. 110, 6 p., 104431.Research output: Contribution to journal › Journal article › Research › peer-review
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Cognitive impairments four months after COVID-19 hospital discharge: Pattern, severity and association with illness variables
Miskowiak, Kamilla, Johnsen, Stine, Sattler, Stefan M, Nielsen, S., Kunalan, K., Rungby, Jørgen, Lapperre, T. & Porsberg, C. M., 2021, In: European Neuropsychopharmacology. 46, p. 39-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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DD2: nye veje i behandlingen af type 2-diabetes
Dansk Endokrinologisk Selskab, D. E. S., Nielsen, J. S., Rungby, Jørgen, Christiansen, J. S., Vaag, Allan, Friborg, S., Sørensen, H. T. & Beck-Nielsen, H., 2014, In: Ugeskrift for Laeger. 176, 11A, V66222.Research output: Contribution to journal › Journal article › Research › peer-review
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Danish Centre for Strategic Research in Type 2 Diabetes (DD2) project cohort of newly diagnosed patients with type 2 diabetes: a cohort profile
Christensen, D. H., Nicolaisen, S. K., Berencsi, K., Beck-Nielsen, H., Rungby, Jørgen, Friborg, S., Brandslund, I., Christiansen, J. S., Vaag, Allan, Sørensen, H. T., Nielsen, J. S. & Thomsen, R. W., 2018, In: BMJ Open. 8, 4, p. 1-11 11 p., e017273.Research output: Contribution to journal › Journal article › Research › peer-review
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Detection of glycan shedding in the blood: New class of multiple sclerosis biomarkers?
DellaValle, B., Manresa-Arraut, A., Hasseldam, Henrik, Stensballe, A., Rungby, Jørgen, Larsen, A. & Hempel, C., 2018, In: Frontiers in Immunology. 9, 9 p., 1254.Research output: Contribution to journal › Journal article › Research › peer-review
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Development and evaluation of a glucagon sensitivity test
Kjeldsen, Sasha Alexandra Sampson, Jensen, N. J., Nilsson, M. S. D., Nybing, J. D., Linden, F. H., Hogh-Schmidt, E., Boesen, Mikael Ploug, Madsbad, Sten, Vilstrup, H. V. A., Rashu, E. B., Gluud, Lise Lotte, Haugaard, Steen Bendix, Holst, Jens Juul, Rungby, Jørgen & Albrechtsen, Nicolai Jacob Wewer, 2021, In: Diabetologia. 64, SUPPL 1, p. 189-189 365.Research output: Contribution to journal › Conference abstract in journal › Research
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Development of a glucagon sensitivity test in humans: Pilot data and the GLUSENTIC study protocol
Kjeldsen, S. A. S., Richter, M. M., Jensen, N. J., Nilsson, M. S. D., Heinz, N., Nybing, J. D., Linden, F. H., Høgh-Schmidt, E., Boesen, M. P., Madsbad, S., Vilstrup, H., Schiødt, F. V., Møller, A., Nørgaard, K., Schmidt, S., Rashu, E. B., Gluud, L. L., Haugaard, S. B., Holst, J. J., Rungby, J. & 1 others, , 2023, In: Peptides. 161, 10 p., 170938.Research output: Contribution to journal › Journal article › Research › peer-review
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Diabetes, antidiabetic medications and risk of depression – A population-based cohort and nested case-control study
Wium-Andersen, I. K., Osler, Merete, Jørgensen, Martin Balslev, Rungby, Jørgen & Wium-Andersen, M. K., 2022, In: Psychoneuroendocrinology. 140, 105715.Research output: Contribution to journal › Journal article › Research › peer-review
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Diabetic Ketoacidosis in a Patient with Type 2 Diabetes After Initiation of Sodium-Glucose Cotransporter 2 Inhibitor Treatment
Storgaard, H., Bagger, J. I., Knop, Filip Krag, Vilsbøll, Tina & Rungby, Jørgen, Feb 2016, In: Basic & Clinical Pharmacology & Toxicology. 118, 2, p. 168-170 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Different mechanisms involved in liraglutide and glucagon-like peptide-1 vasodilatation in rat mesenteric small arteries
Bangshaab, M., Gutierrez, A., Huynh, K. D., Knudsen, J. S., Arcanjo, D. D. R., Petersen, A. G., Rungby, Jørgen, Gejl, M. & Simonsen, U., 2019, In: British Journal of Pharmacology. 176, 3, p. 386-399Research output: Contribution to journal › Journal article › Research › peer-review
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Differential regulation of lipid and protein metabolism in obese vs. lean subjects before and after a 72-h fast
Bak, A. M., Møller, A. B., Vendelbo, M. H., Nielsen, Thomas Svava, Viggers, R., Rungby, Jørgen, Pedersen, S. B., Jørgensen, J. O. L., Jessen, N. & Møller, N., 1 Jul 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 311, 1, p. E224-35 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Discontinuation of diabetes medication in the 10 years before death in Denmark: a register-based study
Kosjerina, V., Carstensen, Bendix, Jørgensen, M. E., Brock, Birgitte, Christensen, H. R., Rungby, Jørgen & Andersen, G. S., 1 Sep 2021, In: The Lancet Healthy Longevity. 2, 9, p. e561-e570 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Early-onset type 2 diabetes: Age gradient in clinical and behavioural risk factors in 5115 persons with newly diagnosed type 2 diabetes-Results from the DD2 study
Bo, A., Thomsen, R. W., Nielsen, J. S., Nicolaisen, S. K., Beck-Nielsen, H., Rungby, Jørgen, Sørensen, H. T., Hansen, T. K., Søndergaard, J., Friborg, S., Lauritzen, T. & Maindal, H. T., 2018, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 34, 3, 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of Influenza Vaccination on Risk of Coronavirus Disease 2019: A Prospective Cohort Study of 46 000 Healthcare Workers( )
Kristensen, J. H., Hasselbalch, R. B., Pries-Heje, M., Nielsen, P. B., Knudsen, A. D., Fogh, K., Norsk, J. B., Eiken, A., Andersen, O., Fischer, T. K., Jensen, C. A. J., Torp-Pedersen, C., Rungby, J., Ditlev, S. B., Hageman, I., Mogelvang, R., Gybel-Brask, M., Dessau, R. B., Sørensen, E., Harritshøj, L. & 9 others, , 2022, In: Journal of Infectious Diseases. 226, 1, p. 6-10 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of Ketone Bodies on Brain Metabolism and Function in Neurodegenerative Diseases
Jensen, N. J., Wodschow, H. Z., Nilsson, M. & Rungby, Jørgen, 2020, In: International Journal of Molecular Sciences . 21, 22, 17 p., 8767.Research output: Contribution to journal › Review › Research › peer-review
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Effects of hypoglycaemia on working memory and regional cerebral blood flow in type 1 diabetes: a randomised, crossover trial
Gejl, M., Gjedde, Albert, Brock, Birgitte, Møller, A., van Duinkerken, E., Haahr, H. L., Hansen, C. T., Chu, P. L., Stender-Petersen, K. L. & Rungby, Jørgen, Mar 2018, In: Diabetologia. 61, 3, p. 551–561Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of two- and twelve-weeks sodium-glucose cotransporter 2 inhibition on DNA and RNA oxidation: two randomized, placebo-controlled trials
Larsen, E. L., Andersen, A., Kjær, L. K., Eickhoff, M. K., Frimodt-Møller, M., Persson, F., Rossing, Peter, Lykkesfeldt, Jens, Knop, Filip Krag, Vilsbøll, Tina, Rungby, Jørgen & Poulsen, Henrik Enghusen, 2023, In: Free Radical Research. 57, 2, p. 140-151Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of β-hydroxybutyrate on cognition in patients with type 2 diabetes
Jensen, N. J., Nilsson, M., Ingerslev, J. S., Olsen, D. A., Fenger, M., Svart, M., Møller, N., Zander, M., Miskowiak, Kamilla & Rungby, Jørgen, 2020, In: European Journal of Endocrinology. 182, 2, p. 233-242 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Elevated levels of 8-oxoGuo and 8-oxodG in individuals with severe mental illness – An autopsy-based study
Christensen, M. R., Poulsen, Henrik Enghusen, Henriksen, T., Weimann, A., Ellervik, Christina, Lynnerup, Niels, Rungby, Jørgen & Banner, Jytte, 1 Oct 2018, In: Free Radical Biology and Medicine. 126, p. 372-378Research output: Contribution to journal › Journal article › Research › peer-review
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Establishing post mortem criteria for the metabolic syndrome: an autopsy based cross-sectional study
Christensen, M. R., Bugge, A., Malik, M. E., Thomsen, J. L., Lynnerup, Niels, Rungby, Jørgen & Banner, Jytte, 2018, In: Diabetology & Metabolic Syndrome. 10, 1, 8 p., 36.Research output: Contribution to journal › Journal article › Research › peer-review
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Experimental non-severe hypoglycaemia substantially impairs cognitive function in type 2 diabetes: a randomised crossover trial
Nilsson, M., Jensen, N., Gejl, M., Bergmann, M. L., Storgaard, H., Zander, M., Miskowiak, Kamilla & Rungby, Jørgen, Oct 2019, In: Diabetologia. 62, 10, p. 1948-1958Research output: Contribution to journal › Journal article › Research › peer-review
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Expression Patterns and Correlations with Metabolic Markers of Zinc Transporters ZIP14 and ZNT1 in Obesity and Polycystic Ovary Syndrome
Maxel, T., Svendsen, P. F., Smidt, K., Lauridsen, J. K., Brock, B., Pedersen, S. B., Rungby, Jørgen & Larsen, A., 2017, In: Frontiers in Endocrinology. 8, 11 p., 38.Research output: Contribution to journal › Journal article › Research › peer-review
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GLP-1 Receptor Agonism Preserves Hippocampal Glucose Metabolism in Alzheimer’s Disease
Gejl, M., Brock, B., Egefjord, L., Vang, K., Gjedde, Albert & Rungby, Jørgen, 2017, In: Diabetes. 66, Supplement 1, p. A63 1 p., 241‑OR.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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GLP-1 analog raises glucose transport capacity of blood-brain barrier in Alzheimer's disease
Gejl, M., Brock, B., Egefjord, L., Rungby, Jørgen & Gjedde, Albert, Apr 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 1 suppl, p. 21-22Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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GLP-1 and Amylin in the Treatment of Obesity
Jorsal, T., Rungby, Jørgen, Knop, Filip Krag & Vilsbøll, Tina, Jan 2016, In: Current Diabetes Reports. 16, 1.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon augments the secretion of FGF21 and GDF15 in MASLD by indirect mechanisms
Richter, Michael Martin, Kemp, I. M., Heebøll, S., Winther-Sørensen, Marie, Kjeldsen, Sasha Alexandra Sampson, Jensen, N. J., Nybing, J. D., Linden, F. H., Høgh-Schmidt, E., Boesen, Mikael Ploug, Madsbad, Sten, Schiødt, Frank Vinholt, Nørgaard, Kirsten, Schmidt, S., Gluud, Lise Lotte, Haugaard, Steen Bendix, Holst, Jens Juul, Nielsen, S., Rungby, Jørgen & Albrechtsen, Nicolai Jacob Wewer, 2024, In: Metabolism: Clinical and Experimental. 156, 13 p., 155915.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon does not directly stimulate pituitary secretion of ACTH, GH or copeptin
Stangerup, I., Kjeldsen, Sasha Alexandra Sampson, Richter, Michael Martin, Jensen, N. J., Rungby, Jørgen, Haugaard, Steen Bendix, Georg, B., Hannibal, Jens, Møllgård, Kjeld, Albrechtsen, Nicolai Jacob Wewer & Holst, Camilla Bjørnbak, 2024, In: Peptides. 176, 7 p., 171213.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide-1 analog, Liraglutide, delays onset of experimental autoimmune encephalitis in Lewis rats
Della Valle, B. W., Brix, G. S., Brock, B., Gejl, M., Landau, A. M., Moller, A., Rungby, Jørgen & Larsen, A., 18 Nov 2016, In: Frontiers in Pharmacology. 7, 7 p., 433.Research output: Contribution to journal › Journal article › Research › peer-review
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Hemoglobin A1c-levels and subsequent risk of depression in individuals with and without diabetes
Wium-Andersen, I. K., Hengeveld, E. M., Rungby, Jørgen, Jørgensen, M. B., Osler, Merete & Wium-Andersen, M. K., 2021, In: Journal of Diabetes and its Complications. 35, 8, 8 p., 107946.Research output: Contribution to journal › Journal article › Research › peer-review
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High BMI levels associate with reduced mRNA expression of IL10 and increased mRNA expression of iNOS (NOS2) in human frontal cortex
Lauridsen, J. K., Olesen, R. H., Vendelbo, J., Hyde, T. M., Kleinman, J. E., Bibby, B. M., Brock, B., Rungby, Jørgen & Larsen, A., 2017, In: Translational Psychiatry. 7, 7 p., e1044.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypercortisolism in Newly Diagnosed Type 2 Diabetes: A Prospective Study of 384 Newly Diagnosed Patients
Steffensen, C., Dekkers, O. M., Lyhne, J., Pedersen, B. G., Rasmussen, F., Rungby, Jørgen, Poulsen, P. L. & Jorgensen, J. O. L., 2019, In: Hormone and Metabolic Research. 51, 1, p. 62-68 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypoglycaemia reduces cognitive performance and affects cerebral blood flow in subjects with type 1 diabetes
Gjedde, Albert, Gejl, M., Brock, B., Moller, A., van Duinkerken, E., Stender-Petersen, K., Hansen, C. T., Chu, P. -., Haahr, H. & Rungby, Jørgen, Sep 2015, In: Diabetologia. 58, 1 Supplement, p. S423-S423 1 p., 879.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Identification of pathogenic GCK variants in patients with common type 2 diabetes can lead to discontinuation of pharmacological treatment
Thuesen, Anne Cathrine Baun, Jensen, Rasmus Tanderup, Maagensen, H., Kristiansen, M. R., Sørensen, H. T., Vaag, Allan, Beck-Nielsen, H., Pedersen, Oluf Borbye, Grarup, Niels, Nielsen, J. S., Rungby, Jørgen, Gjesing, A. P., Storgaard, H., Vilsbøll, Tina & Hansen, Torben, 2023, In: Molecular Genetics and Metabolism Reports. 35, 8 p., 100972.Research output: Contribution to journal › Journal article › Research › peer-review
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In Alzheimer's disease, 6-month treatment with GLP-1 analog prevents decline of brain glucose metabolism: Randomized, placebo-controlled, double-blind clinical trial
Gejl, M., Gjedde, Albert, Egefjord, L., Møller, A., Hansen, S. B., Vang, K., Rodell, A., Brændgaard, H., Gottrup, H., Schacht, A. C., Møller, N., Brock, Birgitte & Rungby, Jørgen, 2016, In: Frontiers in Aging Neuroscience. 8, 10 p., 108.Research output: Contribution to journal › Journal article › Research › peer-review
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In Alzheimer's disease, amyloid beta accumulation is a protective mechanism that ultimately fails
Rischel, E. B., Gejl, M., Brock, Birgitte, Rungby, Jørgen & Gjedde, Albert, 2023, In: Alzheimer's and Dementia. 19, 3, p. 771–783 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased frequency of rare missense PPP1R3B variants among Danish patients with type 2 diabetes
Niazi, R. K., Sun, J., Have, C. T., Hollensted, M., Linneberg, Allan René, Pedersen, Oluf Borbye, Nielsen, J. S., Rungby, Jørgen, Grarup, Niels, Hansen, Torben & Gjesing, A. P., 2019, In: PLoS ONE. 14, 1, p. 1-12 e0210114.Research output: Contribution to journal › Journal article › Research › peer-review
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Increasing BMI is associated with reduced expression of P-glycoprotein (ABCB1 gene) in the human brain with a stronger association in African Americans than Caucasians
Vendelbo, J., Olesen, R. H., Lauridsen, J. K., Rungby, Jørgen, Kleinman, J. E., Hyde, T. M. & Larsen, A., 2018, In: Pharmacogenomics Journal. 18, p. 121-126Research output: Contribution to journal › Journal article › Research › peer-review
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Kønshormoners rolle i udviklingen af melasma
Goandal, N. F., Rungby, Jørgen & Karmisholt, Katrine Elisabeth, 7 Feb 2022, In: Ugeskrift for Laeger. 184, 6, 8 p., V10210769.Research output: Contribution to journal › Review › Research › peer-review
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Lipødem
Andersen, M. T., Burian, E. A., Nissen, Christoffer Valdemar S, Rungby, Jørgen & Karlsmark, T., 2022, In: Ugeskrift for Laeger. 184, 51, 9 p., V04220244.Research output: Contribution to journal › Review › Research › peer-review
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Mannose-binding lectin and risk of cardiovascular events and mortality in type 2 diabetes: A Danish cohort study
Gedebjerg, A., Bjerre, M., Kjaergaard, A. D., Steffensen, R., Nielsen, J. S., Rungby, Jørgen, Friborg, S. G., Brandslund, I., Thiel, S., Beck-Nielsen, H., Sørensen, H. T., Hansen, T. K. & Thomsen, R. W., 2020, In: Diabetes Care. 43, 9, p. 2190-2198 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 129470622
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292
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Blood-Brain Glucose Transfer in Alzheimer's disease: Effect of GLP-1 Analog Treatment
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
233
downloads
In Alzheimer's disease, 6-month treatment with GLP-1 analog prevents decline of brain glucose metabolism: Randomized, placebo-controlled, double-blind clinical trial
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
191
downloads
High BMI levels associate with reduced mRNA expression of IL10 and increased mRNA expression of iNOS (NOS2) in human frontal cortex
Research output: Contribution to journal › Journal article › Research › peer-review
Published