Eric Paul Bennett
Associate Professor
Section 03 - Radiology
Nørre Allé 20
2200 København N
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Control of O-glycan branch formation: Molecular cloning of human cDNA encoding a novel ¿1,6-N-acetylglycosaminyltransferase forming core 2 and core 4
Schwientek, T., Nomoto, M., Levery, S. B., Merkx, G., van Kessel, A. G., Bennett, Eric Paul, Hollingsworth, M. A. & Clausen, Henrik, 1999, In: Journal of Biological Chemistry. 274, p. 4504-4512Research output: Contribution to journal › Journal article › Research › peer-review
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Glycan bioengineering in immunogen design for tumor T antigen immunotargeting
Sendra, V. G., Zlocowski, N., Ditamo, Y., Copioli, S., Tarp, M. P., Bennett, Eric Paul, Clausen, Henrik, Roth, G. A., Nores, G. A. & Irazoqui, F. J., 2009, In: Molecular Immunology. 46, 16, p. 3445-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology
Steentoft, C., Vakhrushev, Sergey, Joshi, Hiren Jitendra, Kong, Y., Vester-Christensen, M. B., Schjoldager, Katrine Ter-Borch Gram, Lavrsen, K., Dabelsteen, Sally, Pedersen, N. B., da Silva, L. P. M., Gupta, R., Bennett, Eric Paul, Mandel, Ulla, Brunak, Søren, Wandall, Hans H., Levery, S. B. & Clausen, Henrik, 15 May 2013, In: E M B O Journal. 32, 10, p. 1478-1488 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glycoengineering of Human Cell Lines Using Zinc Finger Nuclease Gene Targeting: SimpleCells with Homogeneous GalNAc O-glycosylation Allow Isolation of the O-glycoproteome by One-Step Lectin Affinity Chromatography
Steentoft, C., Bennett, Eric Paul & Clausen, Henrik, 2013, Glycosyltransferases: Methods and Protocols. Brockhausen, I. (ed.). Humana Press, Vol. 1022. p. 387-402 16 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
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Precision genome editing: A small revolution for glycobiology
Steentoft, C., Bennett, Eric Paul, Schjoldager, Katrine Ter-Borch Gram, Vakhrushev, Sergey, Wandall, Hans H. & Clausen, Henrik, Aug 2014, In: Glycobiology. 24, 8, p. 663-80 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A validated collection of mouse monoclonal antibodies to human glycosyltransferases functioning in mucin-type O-glycosylation.
Steentoft, C., Yang, Zhang, Wang, S., Ju, T., Vester-Christensen, M. B., Festari, M. F., King-Smith, S. L., Moremen, K., Larsen, I. S. B., Goth, C. K., Schjoldager, Katrine Ter-Borch Gram, Hansen, Lars, Bennett, Eric Paul, Mandel, Ulla & Narimatsu, Yoshiki, 2019, In: Glycobiology. 29, 9, p. 645–656 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mining the O-glycoproteome using zinc-finger nuclease-glycoengineered SimpleCell lines
Steentoft, C., Vakhrushev, Sergey, Vester-Christensen, M. B., Schjoldager, Katrine Ter-Borch Gram, Kong, Y., Bennett, Eric Paul, Mandel, Ulla, Wandall, Hans H., Levery, S. B. & Clausen, Henrik, Oct 2011, In: Nature Methods. 8, 11, p. 977-82 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cloning and expression of the histo-blood group PkUDP-galactose: al¿1-4Glc¿l-Cer ßl,4-Galactosyltransferase
Steffensen, R., Carlier, K., Wiels, J., Levery, S. B., Stroud, M., Cedergren, B., Sojka Nilsson, B., Bennett, Eric Paul, Jersild, C. & Clausen, Henrik, 2000, In: Journal of Biological Chemistry. 275, p. 16723-16729Research output: Contribution to journal › Journal article › Research › peer-review
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A novel α-N-acetylgalactosaminidase family with an NAD +-dependent catalytic mechanism suitable for enzymatic removal of blood group A antigens
Sulzenbacher, G., Liu, Q. P., Bennett, Eric Paul, Levery, S. B., Bourne, Y., Ponchel, G., Clausen, Henrik & Henrissat, B., 1 Jan 2010, In: Biocatalysis and Biotransformation. 28, 1, p. 22-32 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Expression of three UDP-N- og a-D-galactosamine: Polypeptide Ga1NAc N-acetygalactosaminyltransferases in adenocarcinoma cell lines
Sutherlin, M. E., Nishimori, I., Caffrey, T., Bennett, Eric Paul, Hassan, H. S., Mandal, U., Mack, D., Iwamura, T., Clausen, Henrik & Hollingsworth, M. A., 1997, In: Cancer Research. 57, p. 4744Research output: Contribution to journal › Journal article › Research › peer-review
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The glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells
Tian, W., Ye, Z., Wang, S., Schulz, M. A., Van Coillie, Julie, Sun, L., Chen, Yen-Hsi, Narimatsu, Yoshiki, Hansen, Lars, Kristensen, C., Mandel, Ulla, Bennett, Eric Paul, Jabbarzadeh-Tabrizi, S., Schiffmann, R., Shen, J., Vakhrushev, Sergey, Clausen, Henrik & Yang, Zhang, 2019, In: Nature Communications. 10, 13 p., 1785.Research output: Contribution to journal › Journal article › Research › peer-review
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Enhanced mass spectrometric mapping of the human GalNAc-type O-glycoproteome with SimpleCells
Vakhrushev, Sergey, Steentoft, C., Vester-Christensen, M. B., Bennett, Eric Paul, Clausen, Henrik & Levery, S. B., Apr 2013, In: Molecular and Cellular Proteomics. 12, 4, p. 932-44 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Flow cytometry-based assay to evaluate human serum MUC1-Tn antibodies
Van Elssen, C. H. M. J., Clausen, Henrik, Germeraad, W. T. V., Bennett, Eric Paul, Menheere, P. P., Bos, G. M. J. & Vanderlocht, J., 28 Feb 2011, In: Journal of Immunological Methods. 365, 1-2, p. 87-94 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mining the O-mannose glycoproteome reveals cadherins as major O-mannosylated glycoproteins
Vester-Christensen, M. B., Halim, Adnan, Joshi, Hiren Jitendra, Steentoft, C., Bennett, Eric Paul, Levery, S. B., Vakhrushev, Sergey & Clausen, Henrik, 24 Dec 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 52, p. 21018-23 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Generation of monoclonal antibodies to native active human glycosyltransferases
Vester-Christensen, M. B., Bennett, Eric Paul, Clausen, Henrik & Mandel, Ulla, 2013, Glycosyltransferases: Methods and Protocols. Brockhausen, I. (ed.). Humana Press, p. 403-420 18 p. (Methods in Molecular Biology, Vol. 1022).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
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Substrate specificities of three members of the human UDP-N-acetyl-alpha-D-galactosamine:Polypeptide N-acetylgalactosaminyltransferase family, GalNAc-T1, -T2, and -T3.
Wandall, Hans H., Hassan, H., Mirgorodskaya, E., Kristensen, A. K., Roepstorff, P., Bennett, Eric Paul, Nielsen, P. A., Hollingsworth, M. A., Burchell, J., Taylor-Papadimitriou, J. & Clausen, Henrik, 1997, In: Journal of Biological Chemistry. 272, 38, p. 23503-14 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The origin and function of platelet glycosyltransferases
Wandall, Hans H., Rumjantseva, V., Sørensen, A. L. T., Patel-Hett, S., Josefsson, E. C., Bennett, Eric Paul, Italiano, J. E., Clausen, Henrik, Hartwig, J. H. & Hoffmeister, K. M., 19 Jul 2012, In: Blood. 120, 3, p. 626-635 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cancer biomarkers defined by autoantibody signatures to aberrant O-glycopeptide epitopes
Wandall, Hans H., Blixt, O., Tarp, M. A., Pedersen, J. W., Bennett, Eric Paul, Mandel, Ulla, Ragupathi, G., Livingston, P. O., Hollingsworth, M. A., Taylor-Papadimitriou, J., Burchell, J. & Clausen, Henrik, 2010, In: Cancer Research. 70, 4, p. 1306-13 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The lectin domains of polypeptide GalNAc-transferases exhibit carbohydrate-binding specificity for GalNAc: lectin binding to GalNAc-glycopeptide substrates is required for high density GalNAc-O-glycosylation
Wandall, Hans H., Irazoqui, F., Tarp, M. A., Bennett, Eric Paul, Mandel, Ulla, Takeuchi, H., Kato, K., Irimura, T., Suryanarayanan, G., Hollingsworth, M. A. & Clausen, Henrik, 2007, In: Glycobiology. 17, 4, p. 374-87 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions
Wang, S., Mao, Y., Narimatsu, Y., Ye, Z., Tian, W., Goth, C. K., Lira-Navarrete, E., Pedersen, N. B., Benito-Vicente, A., Martin, C., Uribe, K. B., Hurtado-Guerrero, R., Christoffersen, C., Seidah, N. G., Nielsen, R., Christensen, E. I., Hansen, L., Bennett, E. P., Vakhrushev, S. Y., Schjoldager, K. T. & 1 others, , 2018, In: The Journal of Biological Chemistry. 293, 19, p. 7408 –7422Research output: Contribution to journal › Journal article › Research › peer-review
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Purification and cDNA cloning of a human UDP-N-acetyl-a-D-galactosamine: Polypeptide N-Acetylgalctosaminyltransferase
White, T., Bennett, Eric Paul, Takio, K., Sørensen, T., Bonding, N. & Clausen, H., 1995, In: Journal of Biological Chemistry. 270, p. 24156-24165Research output: Contribution to journal › Journal article › Research › peer-review
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Toward stable genetic engineering of human o-glycosylation in plants
Yang, Z., Bennett, Eric Paul, Jørgensen, Bodil, Drew, D. P., Arigi, E. A., Mandel, Ulla, Ulvskov, Peter, Levery, S. B., Clausen, Henrik & Petersen, Bent L, 2012, In: Plant Physiology. 160, 1, p. 450-463 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The GalNAc-type O-glycoproteome of CHO cells characterized by the SimpleCell strategy
Yang, Zhang, Halim, Adnan, Narimatsu, Yoshiki, Joshi, Hiren Jitendra, Steentoft, C., Schjoldager, Katrine Ter-Borch Gram, Schulz, M. A., Sealover, N. R., Kayser, K. J., Bennett, Eric Paul, Levery, S. B., Vakhrushev, Sergey & Clausen, Henrik, Dec 2014, In: Molecular & Cellular Proteomics. 13, 12, p. 3224-3235 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Engineered CHO cells for production of diverse, homogeneous glycoproteins
Yang, Zhang, Wang, S., Halim, Adnan, Schulz, M. A., Frödin, Morten, Rahman, S. H., Vester-Christensen, M. B., Behrens, C., Kristensen, C., Vakhrushev, Sergey, Bennett, Eric Paul, Wandall, Hans H. & Clausen, Henrik, 20 Jul 2015, In: Nature Biotechnology. 33, 8, p. 842-844 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Engineering Mammalian Mucin-type O-Glycosylation in Plants
Yang, Zhang, Drew, D. P., Jørgensen, Bodil, Mandel, Ulla, Bach, S. S., Ulvskov, Peter, Levery, S. B., Bennett, Eric Paul, Clausen, Henrik & Petersen, Bent L, 14 Feb 2012, In: Journal of Biological Chemistry. 287, 15, p. 11911-23 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 11788
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Improved CRISPR/Cas9 gene editing by fluorescence activated cell sorting of green fluorescence protein tagged protoplasts
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Precise integration of inducible transcriptional elements (PrIITE) enables absolute control of gene expression
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The glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells
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