Lars Hviid
Professor
Centre for Medical Parasitology
CMP
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-11-TR4
Member of:
SURFACE team
- Published
Modulation of the cellular immune response during Plasmodium falciparum infections in sickle cell trait individuals
Abu-Zeid, Y. A., Theander, Thor Grundtvig, Abdulhadi, N. H., Hviid, Lars, Saeed, B. O., Jepsen, S., Jensen, J. B. & Bayoumi, R. A., 1992, In: Clinical and Experimental Immunology. 88, 1, p. 112-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Seasonal changes in cell mediated immune responses to soluble Plasmodium falciparum antigens in children with haemoglobin AA and haemoglobin AS
Abu-Zeid, Y. A., Abdulhadi, N. H., Theander, Thor Grundtvig, Hviid, Lars, Saeed, B. O., Jepsen, S., Jensen, J. B. & Bayoumi, R. A., 1992, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 86, 1, p. 20-2 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lymphoproliferative responses to Plasmodium falciparum antigens in children with and without the sickle cell trait
Abu-Zeid, Y. A., Abdulhadi, N. H., Hviid, Lars, Theander, Thor Grundtvig, Saeed, B. O., Jepsen, S., Jensen, J. B. & Bayoumi, R. A., 1991, In: Scandinavian Journal of Immunology. 34, 2, p. 237-42 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Distinct patterns of cytokine regulation in discrete clinical forms of Plasmodium falciparum malaria
Akanmori, B. D., Kurtzhals, Jørgen, Goka, B. Q., Adabayeri, V., Ofori, M. F., Nkrumah, F. K., Behr, C. & Hviid, Lars, 2000, In: European Cytokine Network. 11, 1, p. 113-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Kinetics of B Cell responses to Plasmodium falciparum erythrocyte membrane protein 1 in Ghanaian women naturally exposed to malaria parasites
Ampomah, P., Stevenson, L., Ofori, M. F., Barfod, Lea Klingenberg & Hviid, Lars, 1 Jun 2014, In: Journal of Immunology. 192, 11, p. 5236-44 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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B-cell responses to pregnancy-restricted and -unrestricted Plasmodium falciparum erythrocyte membrane protein 1 antigens in Ghanaian women naturally exposed to malaria parasites
Ampomah, P., Stevenson, L., Ofori, M. F., Barfod, Lea Klingenberg & Hviid, Lars, May 2014, In: Infection and Immunity. 82, 5, p. 1860-71 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The rapid and spontaneous postpartum clearance of Plasmodium falciparum is related to expulsion of the placenta
Anabire, Nsoh Godwin, Quintana Varon, Maria del Pilar, Ofori, M. F. & Hviid, Lars, 2023, In: The Journal of Infectious Diseases. 228, 2, p. 196-201 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High burden of asymptomatic malaria and anaemia despite high adherence to malaria control measures: a cross-sectional study among pregnant women across two seasons in a malaria-endemic setting in Ghana
Anabire, Nsoh Godwin, Aculley, B., Pobee, A., Kyei-Baafour, E., Awandare, G. A., Quintana Varon, Maria del Pilar, Hviid, Lars & Ofori, M. F., 2023, In: Infection. 51, 6, p. 1717-1729Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insecticide-treated bed nets reduce plasma antibody levels and limit the repertoire of antibodies to Plasmodium falciparum variant surface antigens
Askjaer, N., Maxwell, C., Chambo, W., Staalsoe, T., Nielsen, Morten Agertoug, Hviid, Lars, Curtis, C. & Theander, Thor Grundtvig, 2001, In: Clinical and Vaccine Immunology. 8, 6, p. 1289-91 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Modeling malaria infection and immunity against variant surface antigens in Príncipe island, West Africa
Bandeiras, C., Trovoada, M. J., Gonçalves, L. A., Marinho, C. R. F., Turner, Louise, Hviid, Lars, Penha-Gonçalves, C. & Gomes, M. G. M., 2014, In: PloS one. 9, 2, p. e88110Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of α2-macroglobulin, anti-parasite IgM and ABO blood group on rosetting in Plasmodium falciparum clinical isolates and their associations with disease severity in a Ghanaian population
Bandoh, B., Kyei-Baafour, E., Aculley, B., van der Puije, W., Tornyigah, B., Akyea-Mensah, K., Hviid, Lars, Ngala, R. A., Frempong, M. T. & Ofori, M. F., 2022, In: Journal of Blood Medicine. 13, p. 151-164 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA
Barfod, Lea Klingenberg, Bernasconi, N. L., Dahlbäck, M., Jarrossay, D., Andersen, P. H., Salanti, Ali, Ofori, M. F., Turner, Louise, Resende, M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sallusto, F., Lanzavecchia, A. & Hviid, Lars, 2007, In: Molecular Microbiology. 63, 2, p. 335-47 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Chondroitin sulfate A-adhering Plasmodium falciparum-infected erythrocytes express functionally important antibody epitopes shared by multiple variants
Barfod, Lea Klingenberg, Dobrilovic, T., Magistrado, P., Khunrae, P., Viwami, F., Bruun, J., Dahlbäck, M., Bernasconi, N. L., Fried, M., John, D., Duffy, P. E., Salanti, Ali, Lanzavecchia, A., Lim, C. T., Ndam, N. T., Higgins, M. K. & Hviid, Lars, 2010, In: Journal of Immunology. 185, 12, p. 7553-61 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evasion of immunity to Plasmodium falciparum malaria by IgM masking of protective IgG epitopes in infected erythrocyte surface-exposed PfEMP1
Barfod, Lea Klingenberg, Dalgaard, M. B., Pleman, S. T., Ofori, M. F., Pleass, R. J. & Hviid, Lars, 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 30, p. 12485-90 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Baculovirus-expressed constructs induce immunoglobulin G that recognizes VAR2CSA on Plasmodium falciparum-infected erythrocytes
Barfod, Lea Klingenberg, Nielsen, Morten Agertoug, Turner, Louise, Dahlbäck, M., Jensen, Anja Ramstedt, Hviid, Lars, Theander, Thor Grundtvig & Salanti, Ali, 2006, In: Infection and Immunity. 74, 7, p. 4357-60 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell-mediated immune responses to Plasmodium falciparum purified soluble antigens in sickle-cell trait subjects
Bayoumi, R. A., Abu-Zeid, Y. A., Abdulhadi, N. H., Saeed, B. O., Theander, Thor Grundtvig, Hviid, Lars, Ghalib, H. W., Nugud, A. H., Jepsen, S. & Jensen, J. B., 1990, In: Immunology Letters. 25, 1-3, p. 243-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A Novel Domain Cassette Identifies Plasmodium falciparum PfEMP1 Proteins Binding ICAM-1 and Is a Target of Cross-Reactive, Adhesion-Inhibitory Antibodies
Bengtsson, A., Joergensen, L., Rask, T. S., Olsen, R. W., Andersen, M. A., Turner, Louise, Theander, Thor Grundtvig, Hviid, Lars, Higgins, M. K., Craig, A., Brown, A. & Jensen, Anja Ramstedt, 2013, In: Journal of Immunology. 190, 1, p. 240-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transfected HEK293 Cells Expressing Functional Recombinant Intercellular Adhesion Molecule 1 (ICAM-1) - A Receptor Associated with Severe Plasmodium falciparum Malaria
Bengtsson, A., Joergensen, L., Barbati, Z. R., Craig, A., Hviid, Lars & Jensen, Anja Ramstedt, 2013, In: PLOS ONE. 8, 7, p. e69999Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum Expressing Domain Cassette 5 Type PfEMP1 (DC5-PfEMP1) Bind PECAM1
Berger, S. S., Turner, Louise, Wang, Christian William, Petersen, J. E. V., Kraft, M., Lusingu, J. P. A., Mmbando, B., Marquard, A. M., Bengtsson, D. B. A. C., Hviid, Lars, Nielsen, Morten Agertoug, Theander, Thor Grundtvig & Lavstsen, Thomas, 2013, In: PloS one. 8, 7, p. e69117Research output: Contribution to journal › Journal article › Research › peer-review
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Insights into deregulated TNF and IL-10 production in malaria: implications for understanding severe malarial anaemia
Boeuf, P. S., Loizon, S., Awandare, G. A., Tetteh, J. K., Addae, M. M., Adjei, G. O., Goka, B., Kurtzhals, Jørgen, Puijalon, O., Hviid, Lars, Akanmori, B. D. & Behr, C., 2012, In: Malaria Journal. 11, 1, p. 253Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heart failure associated with imported malaria: A nationwide Danish cohort study
Brainin, P., Mohr, G. H., Modin, D., Claggett, B., Silvestre, O. M., Shah, A., Vestergaard, L. S., Jensen , Jens-Ulrik Stæhr , Hviid, Lars, Torp-Pedersen, Christian, Køber, Lars Valeur, Solomon, S., Schou, Morten, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2021, In: ESC heart failure. 8, 5, p. 3521-3529Research output: Contribution to journal › Journal article › Research › peer-review
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Malaria causes long-term effects on markers of iron status in children: a critical assessment of existing clinical and epidemiological tools
Castberg, F. C., Sarbah, E. W., Koram, K. A., Opoku, N., Ofori, M. F., Styrishave, Bjarne, Hviid, Lars & Kurtzhals, Jørgen, 11 Dec 2018, In: Malaria Journal. 17, 1, 464.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased Plasmodium chabaudi malaria mortality in mice with nutritional iron deficiency can be reduced by short-term adjunctive iron supplementation
Castberg, F. C., Maretty, L., Staalsø, Trine, Hempel, C., Clasen-Linde, E., Hviid, Lars & Kurtzhals, Jørgen, 16 Jan 2018, In: Malaria Journal. 17, 1, 12 p., 34.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A longitudinal study of type-specific antibody responses to Plasmodium falciparum merozoite surface protein-1 in an area of unstable malaria in Sudan
Cavanagh, D. R., Elhassan, I. M., Roper, C., Robinson, V. J., Giha, H., Holder, A. A., Hviid, Lars, Theander, Thor Grundtvig, Arnot, D. E. & McBride, J. S., 1998, In: Journal of Immunology. 161, 1, p. 347-59 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential patterns of human immunoglobulin G subclass responses to distinct regions of a single protein, the merozoite surface protein 1 of Plasmodium falciparum
Cavanagh, D. R., Dobaño, C., Elhassan, I. M., Marsh, K., Elhassan, A., Hviid, Lars, Khalil, E. A., Theander, Thor Grundtvig, Arnot, D. E. & McBride, J. S., 2001, In: Infection and Immunity. 69, 2, p. 1207-11 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibodies to the N-terminal block 2 of Plasmodium falciparum merozoite surface protein 1 are associated with protection against clinical malaria
Cavanagh, D. R., Dodoo, D., Hviid, Lars, Kurtzhals, Jørgen, Theander, Thor Grundtvig, Akanmori, B. D., Polley, S., Conway, D. J., Koram, K. & McBride, J. S., 2004, In: Infection and Immunity. 72, 11, p. 6492-502 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian children
Cham, G. K. K., Turner, Louise, Kurtis, J. D., Mutabingwa, T., Fried, M., Jensen, Anja Ramstedt, Lavstsen, Thomas, Hviid, Lars, Duffy, P. E. & Theander, Thor Grundtvig, 2010, In: Infection and Immunity. 78, 11, p. 4653-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Licochalcone A, a new antimalarial agent, inhibits in vitro growth of the human malaria parasite Plasmodium falciparum and protects mice from P. yoelii infection
Chen, M., Theander, Thor Grundtvig, Christensen, Søren Brøgger, Hviid, Lars, Zhai, L. & Kharazmi, A., 1994, In: Antimicrobial Agents and Chemotherapy. 38, 7, p. 1470-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Maternally transmitted antibodies to pregnancy-associated variant antigens on the surface of erythrocytes infected with Plasmodium falciparum: relation to child susceptibility to malaria
Cot, M., Le Hesran, J. Y., Staalsoe, T., Fievet, N., Hviid, Lars & Deloron, P., 2003, In: American Journal of Epidemiology. 157, 3, p. 203-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Maternal vitamin A supplementation and immunity to malaria in pregnancy in Ghanaian primigravids
Cox, S. E., Staalsoe, T., Arthur, P., Bulmer, J. N., Tagbor, H., Hviid, Lars, Frost, C., Riley, E. M. & Kirkwood, B. R., 2005, In: Tropical Medicine & International Health. 10, 12, p. 1286-97 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rapid acquisition of isolate-specific antibodies to chondroitin sulfate A-adherent Plasmodium falciparum isolates in Ghanaian primigravidae
Cox, S. E., Staalsoe, T., Arthur, P., Bulmer, J. N., Hviid, Lars, Yeboah-Antwi, K., Kirkwood, B. R. & Riley, E. M., 2005, In: Infection and Immunity. 73, 5, p. 2841-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Changes in var gene mRNA levels during erythrocytic development in two phenotypically distinct Plasmodium falciparum parasites
Dahlbäck, M., Lavstsen, Thomas, Salanti, Ali, Hviid, Lars, Arnot, D. E., Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2007, In: Malaria Journal. 6, p. 78Research output: Contribution to journal › Journal article › Research › peer-review
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Epitope mapping and topographic analysis of VAR2CSA DBL3X involved in P. falciparum placental sequestration
Dahlbäck, M., Rask, T. S., Andersen, P. H., Nielsen, Morten Agertoug, Ndam, N. T., Resende, M., Turner, Louise, Deloron, P., Hviid, Lars, Lund, O., Pedersen, A. G., Theander, Thor Grundtvig & Salanti, Ali, 2006, In: PLoS Pathogens. 2, 11, p. e124Research output: Contribution to journal › Journal article › Research › peer-review
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Variant surface antigens, virulence genes and the pathogenesis of malaria
Deitsch, K. W. & Hviid, Lars, 2004, In: Trends in Parasitology. 20, 12, p. 562-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Levels of antibody to conserved parts of Plasmodium falciparum merozoite surface protein 1 in Ghanaian children are not associated with protection from clinical malaria
Dodoo, D., Theander, Thor Grundtvig, Kurtzhals, Jørgen, Koram, K., Riley, E., Akanmori, B. D., Nkrumah, F. K. & Hviid, Lars, 1999, In: Infection and Immunity. 67, 5, p. 2131-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Naturally acquired antibodies to the glutamate-rich protein are associated with protection against Plasmodium falciparum malaria
Dodoo, D., Theisen, M., Kurtzhals, Jørgen, Akanmori, B. D., Koram, K. A., Jepsen, S., Nkrumah, F. K., Theander, Thor Grundtvig & Hviid, Lars, 2000, In: Journal of Infectious Diseases. 181, 3, p. 1202-5 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibodies to variant antigens on the surfaces of infected erythrocytes are associated with protection from malaria in Ghanaian children
Dodoo, D., Staalsoe, T., Giha, H., Kurtzhals, Jørgen, Akanmori, B. D., Koram, K., Dunyo, S., Nkrumah, F. K., Hviid, Lars & Theander, Thor Grundtvig, 2001, In: Infection and Immunity. 69, 6, p. 3713-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Functional antibodies against placental malaria parasites are variant dependent and differ by geographic region
Doritchamou, J., Teo, A., Morrison, R., Arora, G., Kwan, J., Manzella-Lapeira, J., Medina-Maldonado, S., Langhorne, J., Hviid, Lars, Narum, D. L., Dicko, A., Fried, M. & Duffy, P. E., 2019, In: Infection and Immunity. 87, 7, 14 p., e00865-18.Research output: Contribution to journal › Journal article › Research › peer-review
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A conformational epitope in placental malaria vaccine antigen VAR2CSA: What does it teach us?
Doritchamou, J. Y. A., Renn, J. P., Hviid, Lars & Duffy, P. E., 2023, In: PLoS Pathogens. 19, 5, e1011370.Research output: Contribution to journal › Journal article › Research › peer-review
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Blood outgrowth endothelial cells (BOECs) as a novel tool for studying adhesion of Plasmodium falciparum-infected erythrocytes
Ecklu-Mensah, G., Olsen, Rebecca Wendelboe, Bengtsson, A., Ofori, M. F., Hviid, Lars, Jensen, Anja Ramstedt & Adams, Yvonne, 2018, In: PLoS ONE. 13, 10, 12 p., e0204177.Research output: Contribution to journal › Journal article › Research › peer-review
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High proportion of subclinical Plasmodium falciparum infections in an area of seasonal and unstable malaria in Sudan
Elhassan, I. M., Hviid, Lars, Jakobsen, P. H., Giha, H., Satti, G. M., Arnot, D. E., Jensen, J. B. & Theander, Thor Grundtvig, 1995, In: American Journal of Tropical Medicine and Hygiene. 53, 1, p. 78-83 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evidence of endothelial inflammation, T cell activation, and T cell reallocation in uncomplicated Plasmodium falciparum malaria
Elhassan, I. M., Hviid, Lars, Satti, G., Akerstrom, B., Jakobsen, P. H., Jensen, J. B. & Theander, Thor Grundtvig, 1994, In: American Journal of Tropical Medicine and Hygiene. 51, 3, p. 372-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Anti-phosphatidylserine antibody levels are low in multigravid pregnant women in a malaria-endemic area in Nigeria, and do not correlate with anti-VAR2CSA antibodies
Fasanya, A., Mohammed, N., Saleh, B. H., Tijani, M. K., Teleka, A., Quintana Varon, Maria del Pilar, Hviid, Lars & Persson, K. E. M., 2023, In: Frontiers in Cellular and Infection Microbiology. 13, 1130186.Research output: Contribution to journal › Journal article › Research › peer-review
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A longitudinal study of human antibody responses to Plasmodium falciparum rhoptry-associated protein 1 in a region of seasonal and unstable malaria transmission
Fonjungo, P. N., Elhassan, I. M., Cavanagh, D. R., Theander, Thor Grundtvig, Hviid, Lars, Roper, C., Arnot, D. E. & McBride, J. S., 1999, In: Infection and Immunity. 67, 6, p. 2975-85 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Selective activation of TCR-G¿ cells in endemic Burkitt's lymphoma
Futagbi, G., Welbeck, J. E., Tetteh, J. K. A., Hviid, Lars & Akanmori, B. D., 2007, In: Malaria Journal. 6, p. 69Research output: Contribution to journal › Journal article › Research › peer-review
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Mannose-binding lectin is a disease modifier in clinical malaria and may function as opsonin for Plasmodium falciparum-infected erythrocytes
Garred, Peter, Nielsen, Morten Agertoug, Kurtzhals, Jørgen, Malhotra, R., Madsen, H. O., Goka, B. Q., Akanmori, B. D., Sim, R. B. & Hviid, Lars, 2003, In: Infection and Immunity. 71, 9, p. 5245-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The epidemiology of febrile malaria episodes in an area of unstable and seasonal transmission
Giha, H. A., Rosthoj, S., Dodoo, D., Hviid, Lars, Satti, G. M., Scheike, Thomas, Arnot, D. E. & Theander, Thor Grundtvig, 2000, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 94, 6, p. 645-51 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Overlapping antigenic repertoires of variant antigens expressed on the surface of erythrocytes infected by Plasmodium falciparum
Giha, H. A., Staalsoe, T., Dodoo, D., Elhassan, I. M., Roper, C., Satti, G. M., Arnot, D. E., Hviid, Lars & Theander, Thor Grundtvig, 1999, In: Parasitology. 119 ( Pt 1), p. 7-17 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Seasonal variation in agglutination of Plasmodium falciparum-infected erythrocytes.
Giha, H. A., Theander, Thor Grundtvig, Staalsø, T., Roper, C., Elhassan, I. M., Babiker, H., Satti, G. M., Arnot, D. E. & Hviid, Lars, 1998, In: American Journal of Tropical Medicine and Hygiene. 58, 4, p. 399-405 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibodies to variable Plasmodium falciparum-infected erythrocyte surface antigens are associated with protection from novel malaria infections
Giha, H. A., Staalsoe, T., Dodoo, D., Roper, C., Satti, G. M., Arnot, D. E., Hviid, Lars & Theander, Thor Grundtvig, 2000, In: Immunology Letters. 71, 2, p. 117-26 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Kinetics of B Cell responses to Plasmodium falciparum erythrocyte membrane protein 1 in Ghanaian women naturally exposed to malaria parasites
Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites
Research output: Contribution to journal › Journal article › Research › peer-review
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B-cell responses to pregnancy-restricted and -unrestricted Plasmodium falciparum erythrocyte membrane protein 1 antigens in Ghanaian women naturally exposed to malaria parasites
Research output: Contribution to journal › Journal article › Research › peer-review
Published