Andres Lopez-Contreras

Andres Lopez-Contreras

Affiliate Associate Professor, Affiliated Associate Professor

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  1. Published

    Supraphysiological protection from replication stress does not extend mammalian lifespan

    Albers, E., Avram, Alexandra Ioana, Sbroggio, M., Fernandez-Capetillo, O. & Lopez-Contreras, Andres, 2020, In: Aging. 12, 7, p. 5612-5624 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    A simple DNA recombination screening method by RT-PCR as an alternative to Southern blot

    Albers, E., Sbroggiò, M., Martin Gonzalez, Javier, Avram, Alexandra Ioana, Munk, S. & Lopez-Contreras, Andres, Jun 2017, In: Transgenic Research. 26, 3, p. 429-434 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Loss of PICH Results in Chromosomal Instability, p53 Activation, and Embryonic Lethality

    Albers, E., Sbroggiò, M., Pladevall Morera, David, Bizard, A. H., Avram, Alexandra Ioana, Gonzalez, P., Martin Gonzalez, Javier, Hickson, Ian David & Lopez-Contreras, Andres, 2018, In: Cell Reports. 24, 12, p. 3274-3284 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality

    Alvarez, S., Díaz, M., Flach, J., Rodriguez-Acebes, S., Lopez-Contreras, Andres, Martínez, D., Cañamero, M., Fernández-Capetillo, O., Isern, J., Passegué, E. & Méndez, J., 12 Oct 2015, In: Nature Communications. 6, p. 8548

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    ATR expands embryonic stem cell fate potential in response to replication stress

    Atashpaz, S., Samadi Shams, S., Martin Gonzalez, Javier, Sebestyén, E., Arghavanifard, N., Gnocchi, A., Albers, E., Minardi, S., Faga, G., Soffientini, P., Allievi, E., Cancila, V., Bachi, A., Fernández-Capetillo, Ó., Tripodo, C., Ferrari, F., Lopez-Contreras, Andres & Costanzo, V., 2020, In: eLife. 9, e54756.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair

    Bunting, S. F., Callén, E., Kozak, M. L., Kim, J. M., Wong, N., Lopez-Contreras, Andres, Ludwig, T., Baer, R., Faryabi, R. B., Malhowski, A., Chen, H., Fernandez-Capetillo, O., D'Andrea, A. & Nussenzweig, A., 27 Apr 2012, In: Molecular Cell. 46, 2, p. 125-35 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    PICH deficiency limits the progression of MYC-induced B-cell lymphoma

    Castejón-Griñán, M., Albers, E., Simón-Carrasco, L., Aguilera, P., Sbroggio, M., Pladevall Morera, David, Ingham, Andreas, Lim, Ernest Wee Kiat, Guillen-Benitez, A., Pietrini, E., Lisby, Michael, Hickson, Ian David & Lopez-Contreras, Andres, 2024, In: Blood Cancer Journal. 14, 1, 15 p., 16.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. A synthetic lethal interaction between APC/C and topoisomerase poisons uncovered by proteomic screens

    Eguren, M., Álvarez-Fernández, M., García, F., Lopez-Contreras, Andres, Fujimitsu, K., Yaguchi, H., Luque-García, J. L., Fernández-Capetillo, O., Muñoz, J., Yamano, H. & Malumbres, M., 27 Feb 2014, In: Cell Reports. 6, 4, p. 670-83 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. PARP-2 sustains erythropoiesis in mice by limiting replicative stress in erythroid progenitors

    Farrés, J., Llacuna, L., Martin-Caballero, J., Martínez, C., Lozano, J. J., Ampurdanés, C., Lopez-Contreras, Andres, Florensa, L., Navarro, J., Ottina, E., Dantzer, F., Schreiber, V., Villunger, A., Fernández-Capetillo, O. & Yélamos, J., 2015, In: Cell Death and Differentiation. 22, p. 1144-157 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Interventions for age-related diseases: Shifting the paradigm

    Figueira, I., Fernandes, A., Mladenovic Djordjevic, A., Lopez-Contreras, Andres, Henriques, C. M., Selman, C., Ferreiro, E., Gonos, E. S., Trejo, J. L., Misra, J., Rasmussen, Lene Juel, Xapelli, S., Ellam, T. & Bellantuono, I., Dec 2016, In: Mechanisms of Ageing and Development. 160, p. 69-92 24 p.

    Research output: Contribution to journal › Review › Research › peer-review

  11. Published

    DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas

    Herrtwich, L., Nanda, I., Evangelou, K., Nikolova, T., Horn, V., Sagar, Erny, D., Stefanowski, J., Rogell, L., Klein, C., Gharun, K., Follo, M., Seidl, M., Kremer, B., Muenke, N., Senges, J., Fliegauf, M., Aschman, T., Pfeifer, D., Sarrazin, S. & 18 others, Sieweke, M. H., Wagner, D., Dierks, C., Haaf, T., Ness, T., Zaiss, M. M., Voll, R. E., Deshmukh, S. D., Prinz, M., Goldmann, T., Hoelscher, C., Hauser, A. E., Lopez-Contreras, Andres, Gruen, D., Gorgoulis, V., Diefenbach, A., Henneke, P. & Triantafyllopoulou, A., 17 Nov 2016, In: Cell. 167, 5, p. 1264–1280.e18

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    TIAR marks nuclear G2/M transition granules and restricts CDK1 activity under replication stress

    Lafarga, V., Sung, H., Haneke, K., Roessig, L., Pauleau, A., Bruer, M., Rodriguez-Acebes, S., Lopez-Contreras, Andres, Gruss, O. J., Erhardt, S., Mendez, J., Fernandez-Capetillo, O. & Stoecklin, G., Jan 2019, In: EMBO Reports. 20, 1, e46224.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. New insights of polyamine metabolism in testicular physiology: A role of ornithine decarboxylase antizyme inhibitor 2 (AZIN2) in the modulation of testosterone levels and sperm motility

    Lambertos, A., Ramos-Molina, B., Lopez-Contreras, Andres, Cremades, A. & Peñafiel, R., 2018, In: PLoS ONE. 13, 12, 22 p., e0209202.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. The mouse Gm853 gene encodes a novel enzyme: Leucine decarboxylase

    Lambertos, A., Ramos-Molina, B., Cerezo, D., Lopez-Contreras, Andres & Peñafiel, R., Mar 2018, In: Biochimica et Biophysica Acta - General Subjects. 1862, 3, p. 365-376 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    USP7 is a SUMO deubiquitinase essential for DNA replication

    Lecona, E., Rodriguez-Acebes, S., Specks, J., Lopez-Contreras, Andres, Ruppen, I., Murga, M., Muñoz, J., Mendez, J. & Fernandez-Capetillo, O., 23 Apr 2016, In: Nature Structural and Molecular Biology. 23, 4, p. 270-277 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. A proteomic characterization of factors enriched at nascent DNA molecules

    Lopez-Contreras, Andres, Ruppen, I., Nieto-Soler, M., Murga, M., Rodriguez-Acebes, S., Remeseiro, S., Rodrigo-Perez, S., Rojas, A. M., Mendez, J., Muñoz, J. & Fernandez-Capetillo, O., 25 Apr 2013, In: Cell Reports. 3, 4, p. 1105-16 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice

    Lopez-Contreras, Andres, Specks, J., Barlow, J. H., Ambrogio, C., Desler, Claus, Vikingsson, S., Rodrigo-Perez, S., Green, H., Rasmussen, Lene Juel, Murga, M., Nussenzweig, A. & Fernandez-Capetillo, O., 1 Apr 2015, In: Genes & Development. 29, 7, p. 690-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. An extra allele of Chk1 limits oncogene-induced replicative stress and promotes transformation

    Lopez-Contreras, Andres, Gutierrez-Martinez, P., Specks, J., Rodrigo-Perez, S. & Fernandez-Capetillo, O., 12 Mar 2012, In: The Journal of Experimental Medicine. 209, 3, p. 455-61 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. The induction of cardiac ornithine decarboxylase by β2 -adrenergic agents is associated with calcium channels and phosphorylation of ERK1/2

    Lopez-Contreras, Andres, de la Morena, M. E., Ramos-Molina, B., Lambertos, A., Cremades, A. & Peñafiel, R., Sep 2013, In: Journal of Cellular Biochemistry. Supplement. 114, 9, p. 1978-86 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. The ATR barrier to replication-born DNA damage

    Lopez-Contreras, Andres & Fernandez-Capetillo, O., 10 Dec 2010, In: DNA Repair. 9, 12, p. 1249-55 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Antizyme inhibitor 2 hypomorphic mice. New patterns of expression in pancreas and adrenal glands suggest a role in secretory processes

    López-Garcia, C., Ramos-Molina, B., Lambertos, A., Lopez-Contreras, Andres, Cremades, A. & Peñafiel, R., 2013, In: PLOS ONE. 8, 7, p. e69188

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Cyclin-dependent kinase inhibitor p21 controls adult neural stem cell expansion by regulating Sox2 gene expression

    Marqués-Torrejón, M. Á., Porlan, E., Banito, A., Gómez-Ibarlucea, E., Lopez-Contreras, Andres, Fernández-Capetillo, O., Vidal, A., Gil, J., Torres, J. & Fariñas, I., 3 Jan 2013, In: Cell Stem Cell. 12, 1, p. 88-100 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. INK4a/ARF limits the expansion of cells suffering from replication stress

    Monasor, A., Murga, M., Lopez-Contreras, Andres, Navas, C., Gomez, G., Pisano, D. G. & Fernandez-Capetillo, O., 15 Jun 2013, In: Cell Cycle. 12, 12, p. 1948-54 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Proteomics Reveals Global Regulation of Protein SUMOylation by ATM and ATR Kinases during Replication Stress

    Munk, S., Sigurðsson, J. O., Xiao, Z., Batth, Tanveer Singh, Franciosa, Giulia, von Stechow, L., Lopez-Contreras, Andres, Vertegaal, A. C. O. & Olsen, Jesper Velgaard, 2017, In: Cell Reports. 21, 2, p. 546-558 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors

    Murga, M., Campaner, S., Lopez-Contreras, Andres, Toledo, L. I., Soria, R., Montaña, M. F., D'Artista, L., Schleker, T., Guerra, C., Garcia, E., Barbacid, M., Hidalgo, M., Amati, B. & Fernandez-Capetillo, O., Dec 2011, In: Nature Structural and Molecular Biology. 18, 12, p. 1331-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 122743856