Birthe Brandt Kragelund

Birthe Brandt Kragelund

Professor

ORCID: 0000-0002-7454-1761

Publication year:
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  1. 1993
  2. Published

    Threedimensional structure of the complex acyl-coenzyme, A binding protein and palmitoyl-coenzyme A

    Kragelund, Birthe Brandt, Andersen, K. V., Madsen, J. C., Knudsen, J. & Poulsen, F., 1993, In: J. Mol. Biol.. 230, p. 1260-1277

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 1995
  4. Published

    Folding of a four-helix bundle. Studies of acyl-coenzyme A binding protein

    Kragelund, Birthe Brandt, Robinson, C. R., Knudsen, J., Dobson, C. M. & Poulsen, F., 1995, In: Biochemistry. 34, p. 7217-7224

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Local perturbations by ligand binding on hydrogen exchange kinetics in a four-helix bundle protein, acyl-coenzyme A binding protein (ACBP)

    Kragelund, Birthe Brandt, Knudsen, J. & Poulsen, F., 1995, In: J. Mol. Biol.. 250, p. 695-706

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 1996
  7. Published

    Thermodynamics of ligand binding to acyl-coenzyme, A binding protein studied by titration calometry

    Færgeman, N. J., Sigurskjold, B. W., Kragelund, Birthe Brandt, Andersen, K. V. & Knudsen, J., 1996, In: Biochemistry. 35, p. 14118-14126

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Fast and one-step folding of closely and distantly related homologous proteins of a four-helix bundle family

    Kragelund, Birthe Brandt, Højrup, P., Jensen, M. S., Schjerling, C. K., Juul, E., Knudsen, J. & Poulsen, F., 1996, In: J. Mol. Biol.. 256, p. 187-200

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Probing the nature of non-covalent interactions by mass spectrometry. A study of protein-CoA ligand interactions and assembly

    Robinson, C. R., Chung, E. W., Kragelund, Birthe Brandt, Knudsen, J., Aplin, R. T., Poulsen, F. & Dobson, C. M., 1996, In: J. Amer. Chem.. 118, p. 8646-8653

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 1997
  11. Published

    Structure of lipid-transfer protein complexed with palmitoyl-CoA. A hydrophobic binding site expandable to fit both large and small lipid-like ligands

    Lerche, M. H., Kragelund, Birthe Brandt, Bech, L. & Poulsen, F., 1997, In: Structure. 5, p. 291-306

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. 1998

  13. Hydrophobic core substitutions in calbindin D9k: effects on Ca2+ binding and dissociation

    Kragelund, Birthe Brandt, Jönsson, M., Bifulco, G., Chazin, W. J., Nilsson, H., Finn, B. E. & Linse, S., 23 Jun 1998, In: Biochemistry. 37, 25, p. 8926-37 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Mapping the lifetimes of local opening events in a native state protein

    Kragelund, Birthe Brandt, Heinemann, B., Knudsen, J. & Poulsen, F., 1998, In: Protein Sci.. 7, p. 2237-2248

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. 1999

  16. Acyl-coenzyme A binding protein (ACBP)

    Kragelund, Birthe Brandt, Knudsen, J. & Poulsen, F. M., 1999, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1441, 2-3, p. 150-161 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. The formation of a native-like structure containing eight conserved hydrophobic residues is rate limiting in two-state protein folding of ACBP

    Kragelund, Birthe Brandt, Osmark, P., Neergaard, T. B., Schiødt, J., Kristiansen, K., Knudsen, J. & Poulsen, F., 1999, In: Nature Structural and Molecular Biology. 6, 6, p. 594-601

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. 2000
  19. Published

    1H, 13C, and 15N assignments of un-myristoylated Ca2+-frequenin, a synaptic efficacy modulator

    Kragelund, Birthe Brandt, Hauenschild, A., Carlström, G., Pongs, O. & Finn, B. E., Jan 2000, In: Journal of Biomolecular N M R. 16, 1, p. 85-6 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Formation of hydrogen bonds precedes the rate-limiting formation of persistent structure in the folding of ACBP

    Teilum, Kaare, Kragelund, Birthe Brandt, Knudsen, J. & Poulsen, F. M., 2000, In: Journal of Molecular Biology. 301, 5, p. 1307-14 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. 2002
  22. Published

    Early kinetic intermediate in the folding of acyl-CoA binding protein detected by fluorescence labeling and ultrarapid mixing

    Teilum, Kaare, Maki, K., Kragelund, Birthe Brandt, Poulsen, F. M. & Roder, H., 2002, In: Proceedings of the National Academy of Science of the United States of America. 99, 15, p. 9807-12 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Transient structure formation in unfolded acyl-coenzyme A-binding protein observed by site-directed spin labelling

    Teilum, Kaare, Kragelund, Birthe Brandt & Poulsen, F. M., 2002, In: Journal of Molecular Biology. 324, 2, p. 349-57 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Transient intermediary states with high and low folding probabilities in the apparent two-state folding equilibrium of ACBP at low pH

    Thomsen, J. K., Kragelund, Birthe Brandt, Teilum, Kaare, Knudsen, J. & Poulsen, F. M., 2002, In: Journal of Molecular Biology. 318, 3, p. 805-14 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Fluorescently labelled bovine acyl-CoA-binding protein acting as an acyl-CoA sensor: interaction with CoA and acyl-CoA esters and its use in measuring free acyl-CoA esters and non-esterified fatty acids

    Wadum, M. C., Villadsen, J. K., Feddersen, S., Moller, R. S., Neergaard, T. B., Kragelund, Birthe Brandt, Hojrup, P., Faergeman, N. J. & Knudsen, J., 2002, In: Biochemical Journal. 365, p. 165-172 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. 2003
  27. Published

    Universitetsstuderendes tilgang til eksperimentelt udstyr - kønslige og faglige aspekter

    Bruun, G. M., Kragelund, Birthe Brandt & Oddershede, L. B., 2003, In: Center for Naturfagenes Didaktiks Tidsskriftserie. 9, p. .

    Research output: Contribution to journal › Journal article › Research

  28. Published

    Universitetsstuderendes tilgang til eksperimentelt udstyr - faglige og kønslige aspekter

    Bruun, G. M., Kragelund, Birthe Brandt & Oddershede, L. B., 2003, Natureveidenskabs didaktik. Museum Tusculanum, Vol. 9. p. 1-37

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  29. 2004
  30. Published

    Structure and biochemical function of a prototypical Arabidopsis U-box domain

    Andersen, P., Kragelund, Birthe Brandt, Olsen, A. N., Larsen, F. H., Chua, N., Poulsen, F. M. & Skriver, Karen, 2004, In: Journal of Biological Chemistry. 279, 38, p. 40053-40061 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. 2005
  32. Published

    Reversible Dimerization of Acid-Denatured ACBP Controlled by Helix A4

    Fieber, W., Kragelund, Birthe Brandt, Meldal, Morten Peter & Poulsen, F. M., 2005, In: Biochemistry. 44, 5, p. 1375-1384

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Protein folding: Defining a standard set of experimental conditions and a preliminary kinetic data set of two-state proteins

    Maxwell, K. L., Wildes, D., Zarrine-Afsar, A., Rivos, M. A. D. L. R., Brown, A. G., Friel, C. T., Hedberg, L., Horng, J-C., Bona, D., Miller, E. J., Vallée-Bélisle, A., Main, E. R. G., Bemporad, F., Qiu, L., Teilum, K., Vu, N-D., Edwards, A. M., Ruczinski, I., Poulsen, F. M., Kragelund, B. B. & 14 others, Michnick, S. W., Chiti, F., Bai, Y., Hagen, S. J., Serrano, L., Oliveberg, M., Raleigh, D. P., Stafshede, P. W., Radford, S. E., Jackson, S. E., Sosnick, T. R., Margusee, S., Davidson, A. R. & Plaxco, K. W., 2005, In: Protein Science. 14, 3, p. 602-616

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Hydroxylation of the Herbicide Isoproturon by Fungi Isolated from Agricultural soil

    Rønhede, S., Jensen, B., Rosendahl, Søren, Kragelund, Birthe Brandt, Juhler, R. K. & Aamand, J., 2005, In: Applied and Environmental Microbiology. 71, 12, p. 7927-7932

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Application of Hydrogen Exchange Kinetics to Studies of Protein Folding

    Teilum, Kaare, Kragelund, Birthe Brandt & Poulsen, F. M., 2005, Protein Folding Handbook. Buchner, J. & Kiefhaber, T. (eds.). Weinheim: Wiley-VCH, p. 634-672

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  36. Published

    Different secondary structure elements as scaffolds for protein folding transition states of two homologous four-helix bundles

    Teilum, Kaare, Thormann, T., Caterer, N. R., Poulsen, H. I., Jensen, P. H., Knudsen, J., Kragelund, Birthe Brandt & Poulsen, F. M., 2005, In: Proteins - Structure Function and Bioinformatics. 59, 1, p. 80-90

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Solution structure of human prolactin

    Teilum, Kaare, Hoch, J. C., Goffin, V., Kinet, S., Martial, J. A. & Kragelund, Birthe Brandt, 2005, In: Journal of Molecular Biology. 351, 4, p. 810-23 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. 2006
  39. Published

    A loop of coagulation factor VIIa influencing macromolecular substrate specificity.

    Bjelke, J. R., Persson, E., Rasmussen, H. B., Kragelund, Birthe Brandt & Olsen, O. H., 2006, In: FEBS Letters. 581, 1, p. 71-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Binding site structure of one LRP-RAP complex: implications for a common ligand-receptor binding motif.

    Jensen, G. A., Andersen, O. M., Bonvin, A. M. J. J., Bjerrum-Bohr, I., Etzerodt, M., Thøgersen, H. C., O'Shea, Charlotte, Poulsen, F. M. & Kragelund, Birthe Brandt, 2006, In: Journal of Molecular Biology. 362, 4, p. 700-16 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. 2007
  42. Published

    Structure of the human beta-ketoacyl [ACP] synthase from the mitochondrial type II fatty acid synthase

    Christensen, Caspar Elo, Kragelund, Birthe Brandt, Von Wettstein-Knowles, P. & Henriksen, A., Feb 2007, In: Protein Science. 16, 2, p. 261-272

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Acyl-CoA binding proteins; structural and functional conservation over 2000 MYA.

    Faergeman, N. J., Wadum, M., Feddersen, S., Burton, M., Kragelund, Birthe Brandt & Knudsen, J., 2007, In: Molecular and Cellular Biochemistry. 299, 1-2, p. 55-65 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Structural and thermodynamic bases for the design of pure prolactin receptor antagonists: X-ray structure of Del1-9-G129R-hPRL.

    Jomain, J., Tallet, E., Broutin, I., Hoos, S., van Agthoven, J., Ducruix, A., Kelly, P. A., Kragelund, Birthe Brandt, England, P. & Goffin, V., 2007, In: Journal of Biological Chemistry. 282, 45, p. 33118-31 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Engineering the substrate and inhibitor specificities of human coagulation Factor VIIa.

    Larsen, K. S., Østergaard, H., Bjelke, J. R., Olsen, O. H., Rasmussen, H. B., Christensen, L., Kragelund, Birthe Brandt & Stennicke, H. R., 2007, In: Biochemical Journal. 405, 3, p. 429-38 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Structure-activity study of the antibacterial peptide fallaxin

    Søndergaard, S. L., Frimodt-Møller, N., Kragelund, Birthe Brandt & Hansen, Paul Robert, 2007, In: Protein Science. 16, 9, p. 1969-1976 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. 2008
  48. Published

    Mechanism of the Ca2+-induced enhancement of the intrinsic factor VIIa activity

    Bjelke, J. R., Olsen, O. H., Fodje, M., Svensson, L. A., Bang, S., Bolt, G., Kragelund, Birthe Brandt & Persson, E., 2008, In: Journal of Biological Chemistry. 283, 38, p. 25863-70 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    The intrinsically disordered RNR inhibitor Sml1 is a dynamic dimer

    Danielsson, J., Liljedahl, L., Ba´ra´ny-Wallje, E., Sønderby, P., Kristensen, L. H., Martinez-Yamout, M. A., Dyson, H. J., Wright, P. E., Poulsen, F. M., Ma¨ler, L., Gra¨slund, A. & Kragelund, Birthe Brandt, 2008, In: Biochemistry. 47, 50, p. 13428-13437 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Acyl-CoA-binding protein (ACBP) localizes to the endoplasmic reticulum and Golgi in a ligand-dependent manner in mammalian cells.

    Hansen, J. S., Færgeman, N. J., Kragelund, Birthe Brandt & Knudsen, J., 2008, In: Biochemical Journal. 410, 3, p. 463-472 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Phosphate Selective Uranyl Photo-Affinity Cleavage of Proteins. Determination of Phosphorylation Sites.

    Kristensen, L. H., Nielsen, Peter E., Jørgensen, C. I., Kragelund, Birthe Brandt & Møllegaard, Niels Erik, 2008, In: ChemBioChem. 9, 15, p. 2377-81 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. 2009
  53. Published

    Metabolites of the phenylurea herbicides chlorotoluron, diuron, isoproturonand linuron produced by the soil fungus Mortierella sp.

    Badawi, N., Rønhede, S., Olsson, S., Kragelund, Birthe Brandt, Johnsen, A. H., Jacobsen, O. S. & Aamand, J., 2009, In: Environmental Pollution. 157, 10, p. 2806-2812 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Structure of the Mature Streptococcal Cysteine Protease Exotoxin mSpeB in Its Active Dimeric Form

    Olsen, Johan Gotthardt, Dagil, Robert, Niclasen, L. M., Sørensen, O. E. & Kragelund, Birthe Brandt, 2009, In: Journal of Molecular Biology. 393, 3, p. 693-703 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Functional aspects of protein flexibility

    Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2009, In: Cellular and Molecular Life Sciences. 66, 14, p. 2231-47 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. 2010
  57. Published

    Crystal structure of an affinity-matured prolactin complexed to its dimerized receptor reveals the topology of hormone binding site 2.

    Broutin, I., Jomain, J., Tallet, E., Van Agthoven, J., Raynal, B., Hoos, S., Kragelund, Birthe Brandt, Kelly, P., Ducroix, A., England, P. & Goffin, V., 2010, In: Journal of Biological Chemistry. 285, 11, p. 8422-8433 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Temperature-dependent structural changes in intrinsically disordered proteins: formation of alpha-helices or loss of polyproline II?

    Kjærgaard, M., Nørholm, A., Hendus-Altenburger, R., Pedersen, Stine Helene Falsig, Poulsen, F. M. & Kragelund, Birthe Brandt, 1 Aug 2010, In: Protein Science. 19, 8, p. 1555-64 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Regulation of ribonucleotide reductase by Spd1 involves multiple mechanisms

    Nestoras, K., Mohammed, A. H., Schreurs, A., Fleck, O., Watson, A. T., Poitelea, M., O'Shea, Charlotte, Chahwan, C., Holmberg, Christian, Kragelund, Birthe Brandt, Nielsen, Olaf, Osborne, M., Carr, A. M. & Liu, C., 1 Jun 2010, In: Genes & Development. 24, 11, p. 1145-1159 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    A Far UV CD study of de novo designed antimicrobial coiled coils upon interaction with model membranes

    Søndergaard, S. L., Kragelund, Birthe Brandt, Thulstrup, Peter Waaben, Brahm, Jesper, Siegumfeldt, Henrik, Frimodt-Møller, N. & Hansen, Paul Robert, 2010, In: Journal of Peptide Science. S2

    Research output: Contribution to journal › Conference abstract in journal › Research

  61. 2011
  62. Published

    Development of prolactin receptor antagonists with reduced pH-dependence of receptor binding.

    Hansen, M. J. K., Olsen, Johan Gotthardt, Bernichtein, S., O'Shea, Charlotte, Sigurskjold, B. W., Goffin, V. & Kragelund, Birthe Brandt, 2011, In: Journal of Molecular Recognition. 24, 4, p. 533-547 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Senescence-associated barley NAC (NAM, ATAF1,2, CUC) transcription factor interacts with radical-induced cell death 1 through a disordered regulatory domain

    Kjaersgaard, T., Jensen, M. K., Christiansen, M. W., Gregersen, P. L., Kragelund, Birthe Brandt & Skriver, Karen, 2011, In: Journal of Biological Chemistry. 286, 41, p. 35418-29 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Streptococcal pyogenic exotoxin B (SpeB) boosts the contact system via binding of a-1 antitrypsin

    Meinert Niclasen, L., Olsen, Johan Gotthardt, Dagil, Robert, Qing, Z., Sørensen, O. E. & Kragelund, Birthe Brandt, 2011, In: Biochemical Journal. 434, 1, p. 123-32 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    The Intracellular Distal Tail of the Na+/H+ Exchanger NHE1 Is Intrinsically Disordered: Implications for NHE1 Trafficking

    Nørholm, A., Hendus-Altenburger, R., Bjerre, G., Kjærgaard, M., Pedersen, Stine Helene Falsig & Kragelund, Birthe Brandt, 2011, In: Biochemistry. 50, 17, p. 3469-80 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Protein stability, flexibility and function

    Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2011, In: B B A - Proteins and Proteomics. 1814, 8, p. 969-76 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  67. 2012
  68. Published

    The WSXWS motif in cytokine receptors is a molecular switch involved in receptor activation: insight from structures of the prolactin receptor

    Dagil, Robert, Knudsen, M. J., Olsen, Johan Gotthardt, O'Shea, Charlotte, Franzmann, M., Goffin, V., Teilum, Kaare, Breinholt, J. & Kragelund, Birthe Brandt, 2012, In: Structure. 20, 2, p. 270-282 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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