Yong Wang

Yong Wang

Assistant Professor


Publication year:
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1 - 39 out of 39Page size: 50
  1. 2023
  2. Published

    The effect of linker conformation on performance and stability of a two-domain lytic polysaccharide monooxygenase

    Forsberg, Z., Stepnov, A. A., Tesei, Giulio, Wang, Yong, Buchinger, E., Kristiansen, S. K., Aachmann, F. L., Arleth, Lise, Eijsink, V. G. H., Lindorff-Larsen, Kresten & Courtade, G., 2023, In: Journal of Biological Chemistry. 299, 11, 17 p., 105262.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2022
  4. Published

    Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA

    Raghavan, Sai Sundar Rajan, Dagil, Robert, Lopez-Perez, Mary, Conrad, J., Bassi, Maria Rosaria, Quintana Varon, Maria del Pilar, Choudhary, Swati, Gustavsson, Tobias, Wang, Yong, Gourdon, Pontus Emanuel, Ofori, M. F., Christensen, S. B., Minja, D. T. R., Schmiegelow, Christentze, Nielsen, Morten Agertoug, Barfod, Lea Klingenberg, Hviid, Lars, Salanti, Ali, Lavstsen, Thomas & Wang, Kaituo, 2022, In: PLoS Pathogens. 18, 11, e1010924.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Cryo-EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity

    Neumann, C., Rosenbæk, L. L., Flygaard, R. K., Habeck, M., Karlsen, J. L., Wang, Yong, Lindorff-Larsen, Kresten, Gad, H. H., Hartmann, R., Lyons, J. A., Fenton, R. A. & Nissen, P., 2022, In: EMBO Journal. 41, 23, 15 p., e110169.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Identifying Heterozipper β-Sheet in Twisted Amyloid Aggregation

    Song, Y., Dai, B., Wang, Yong, Wang, Y., Liu, C., Gourdon, Pontus Emanuel, Liu, L., Wang, Kaituo & Dong, M., 2022, In: Nano Letters. 22, 9, p. 3707–3712

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Structures of Atm1 provide insight into [2Fe-2S] cluster export from mitochondria

    Li, P., Hendricks, A. L., Wang, Yong, Villones, R. L. E., Lindkvist-Petersson, K., Meloni, G., Cowan, J. A., Wang, Kaituo & Gourdon, Pontus Emanuel, 2022, In: Nature Communications. 13, 1, 12 p., 4339.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The covalent reactivity of functionalized 5-hydroxy-butyrolactams is the basis for targeting of fatty acid binding protein 5 (FABP5) by the neurotrophic agent MT-21

    Svenningsen, E. B., Ottosen, R. N., Jørgensen, K. H., Nisavic, M., Larsen, C. K., Hansen, B. K., Wang, Yong, Lindorff-Larsen, Kresten, Tørring, T., Hacker, S. M., Palmfeldt, J. & Poulsen, T. B., 2022, In: RSC Chemical Biology. 3, 10, p. 1216-1229 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. 2021
  10. Published

    Architecture and assembly dynamics of the essential mitochondrial chaperone complex TIM9·10·12

    Weinhäupl, K., Wang, Yong, Hessel, A., Brennich, M., Lindorff-Larsen, Kresten & Schanda, P., 2021, In: Structure. 29, 9, p. 1065-1073.e4

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Charge Interactions in a Highly Charge-Depleted Protein

    Hervø-Hansen, S., Højgaard, C., Johansson, Kristoffer Enøe, Wang, Yong, Wahni, K., Young, D., Messens, J., Teilum, Kaare, Lindorff-Larsen, Kresten & Winther, Jakob R., 2021, In: Journal of the American Chemical Society. 143, 6, p. 2500-2508 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding

    Wang, Kaituo, Dagil, Robert, Lavstsen, Thomas, Misra, S. K., Spliid, C. B., Wang, Yong, Gustavsson, Tobias, Sandoval, D. R., Vidal-Calvo, E. E., Choudhary, Swati, Agerbæk, Mette Ørskov, Lindorff-Larsen, Kresten, Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sharp, J. S., Clausen, Thomas Mandel, Gourdon, Pontus Emanuel & Salanti, Ali, 2021, In: Nature Communications. 12, 1, 10 p., 2956.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    DEER-PREdict: Software for efficient calculation of spin-labeling EPR and NMR data from conformational ensembles

    Tesei, Giulio, Martins, J. M., Kunze, M. B. A., Wang, Yong, Crehuet, R. & Lindorff-Larsen, Kresten, 2021, In: PLOS Computational Biology. 17, 1, 18 p., e1008551.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Mapping the degradation pathway of a disease-linked aspartoacylase variant

    Andersen, Sarah Gersing, Wang, Yong, Grønbæk-Thygesen, Martin, Kampmeyer, Caroline, Bjørnkjær, Lene, Willemoës, Martin, Andréasson, C., Stein, Amelie, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 2021, In: PLOS Genetics. 17, 4, 28 p., e1009539.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Order and disorder - An integrative structure of the full-length human growth hormone receptor

    Kassem, N., Araya-Secchi, R., Bugge, K., Barclay, A., Steinocher, H., Khondker, A., Wang, Yong, Lenard, A. J., Bürck, J., Sahin, Cagla, Ulrich, A. S., Landreh, M., Pedersen, Martin Cramer, Rheinstädter, M. C., Pedersen, Per Amstrup, Lindorff-Larsen, Kresten, Arleth, Lise & Kragelund, Birthe Brandt, 2021, In: Science Advances. 7, 27, 20 p., eabh3805.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Properdin oligomers adopt rigid extended conformations supporting function

    Pedersen, D. V., Pedersen, M. N., Mazarakis, S. M. M., Wang, Yong, Lindorff-Larsen, Kresten, Arleth, Lise & Andersen, G. R., 2021, In: eLife. 10, 22 p., e63356.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Structural and functional variation of chitin-binding domains of a lytic polysaccharide monooxygenase from Cellvibrio japonicus

    Madland, E., Forsberg, Z., Wang, Yong, Lindorff-Larsen, Kresten, Niebisch, A., Modregger, J., Eijsink, V. G. H., Aachmann, F. L. & Courtade, G., 2021, In: Journal of Biological Chemistry. 297, 4, 17 p., 101084.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. 2020
  19. Published

    Combining molecular dynamics simulations with small-angle X-ray and neutron scattering data to study multi-domain proteins in solution

    Nørgrd Larsen, Andreas, Wang, Yong, Bottaro, S., Grudinin, S., Arleth, Lise & Lindorff-Larsen, Kresten, 2020, In: P L o S Computational Biology. 16, 4, 29 p., e1007870.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Free Energy Profile and Kinetics of Coupled Folding and Binding of the Intrinsically Disordered Protein p53 with MDM2

    Zou, R., Zhou, Y., Wang, Yong, Kuang, G., Ågren, H., Wu, J. & Tu, Y., 2020, In: Journal of Chemical Information and Modeling. 60, 3, p. 1551-1558 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Structural basis of client specificity in mitochondrial membrane-protein chaperones

    Sučec, I., Wang, Yong, Dakhlaoui, O., Weinhäupl, K., Jores, T., Costa, D., Hessel, A., Brennich, M., Rapaport, D., Lindorff-Larsen, Kresten, Bersch, B. & Schanda, P., 2020, In: Science Advances. 6, 51, 15 p., eabd0263.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. 2019
  23. Published

    PSX, Protein-Solvent Exchange: software for calculation of deuterium-exchange effects in small-angle neutron scattering measurements from protein coordinates

    Pedersen, Martin Cramer, Wang, Yong, Tidemand, Frederik Grønbæk, Martel, A., Lindorff-Larsen, Kresten & Arleth, Lise, 2019, In: Journal of Applied Crystallography. 52, 6, p. 1427-1436 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    A Multi-State Coarse-Grained Simulation Model Captures Conformational Cycling in P-Type ATPases

    Wang, Yong, Saleh, N., Chu, X. & Lindorff-Larsen, Kresten, 2019, In: Biophysical Journal. 116, 3, suppl. 1, p. 300a 1484-Plat.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  25. Published

    Allosteric modulation of the sarcoplasmic reticulum Ca2+ ATPase by thapsigargin via decoupling of functional motions

    Saleh, N., Wang, Yong, Nissen, P. & Lindorff-Larsen, Kresten, 2019, In: Physical Chemistry Chemical Physics. 21, 39, p. 21991-21995

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System

    Pedersen, D. V., Gadeberg, T. A. F., Thomas, C., Wang, Yong, Joram, N., Jensen, R. K., Mazarakis, S. M. M., Revel, M., El Sissy, C., Petersen, S. V., Lindorff-Larsen, Kresten, Thiel, S., Laursen, N. S., Fremeaux-Bacchi, V. & Andersen, G. R., 2019, In: Frontiers in Immunology. 10, 19 p., 2007.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Substrate-induced conformational dynamics of the dopamine transporter

    Nielsen, A. K., Möller, I. R., Wang, Yong, Rasmussen, Søren Gøgsig Faarup, Lindorff-Larsen, Kresten, Rand, Kasper Dyrberg & Loland, Claus Juul, 2019, In: Nature Communications. 10, 14 p., 2714.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. 2018
  29. Published

    Frequency adaptive metadynamics for the calculation of rare-event kinetics

    Wang, Yong, Valsson, O., Tiwary, P., Parrinello, M. & Lindorff-Larsen, Kresten, 2018, In: Journal of Chemical Physics. 149, 7, p. 1-7 072309.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Monte Carlo Sampling of Protein Folding by Combining an All-Atom Physics-Based Model with a Native State Bias

    Wang, Yong, Tian, P., Boomsma, Wouter & Lindorff-Larsen, Kresten, 2018, In: Journal of Physical Chemistry B. 122, 49, p. 11174-11185

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Role of protein dynamics in transmembrane receptor signalling

    Wang, Yong, Bugge, K. Ø., Kragelund, Birthe Brandt & Lindorff-Larsen, Kresten, 2018, In: Current Opinion in Structural Biology. 48, p. 74-82 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  32. Published

    Structural Basis of Membrane Protein Chaperoning through the Mitochondrial Intermembrane Space

    Weinhaupl, K., Lindau, C., Hessel, A., Wang, Yong, Schültze, C., Jores, T., Melchionda, L., Schönfisch, B., Kalbacher, H., Bersch, B., Rapaport, D., Brennich, M., Lindorff-Larsen, Kresten, Wiedemann, N. & Schanda, P., 2018, In: Cell. 175, 5, p. 1365-1379, e25

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. 2017
  34. Published

    Biomolecular conformational changes and ligand binding: from kinetics to thermodynamics

    Wang, Yong, Martins, J. & Lindorff-Larsen, Kresten, Sep 2017, In: Chemical Science. 8, 9, p. 6466-6473 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. 2016
  36. Published

    Hybrid Methods and Atomistic Models to Explore Free Energies, Rates and Pathways of Protein Shape Changes

    Wang, Yong, 2016, Department of Biology, Faculty of Science, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis › Research

  37. Published

    Mapping transiently formed and sparsely populated conformations on a complex energy landscape

    Wang, Yong, Papaleo, E. & Lindorff-Larsen, Kresten, 2016, In: eLife. 5, 35 p., e17505.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. 2015
  39. Published

    Structure of a functional amyloid protein subunit computed using sequence variation

    Tian, P., Boomsma, Wouter, Wang, Yong, Otzen, D., Jensen, Mogens Høgh & Lindorff-Larsen, Kresten, 2015, In: Journal of the American Chemical Society. 137, 1, p. 22–25 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. 2014

  41. Dynamic Conformational Change Regulates the Protein-DNA Recognition: An Investigation on Binding of a Y-Family Polymerase to Its Target DNA

    Chu, X., Liu, F., Maxwell, B. A., Wang, Yong, Suo, Z., Wang, H., Han, W. & Wang, J., 2014, In: P L o S One. 10, 9, 15 p., e1003804.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. PolyUbiquitin Chain Linkage Topology Selects the Functions from the Underlying Binding Landscape

    Wang, Yong, Tang, C., Wang, E. & Wang, J., 2014, In: P L o S Computational Biology (Online). 10, 7, 14 p., e1003691.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Reply to Jensen and Blackledge: dual quantifications of intrinsically disordered proteins by NMR ensembles and molecular dynamics simulations

    Wang, Yong, Longhi, S., Roche, P. & Wang, J., 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 16, p. E1559 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. 2013

  45. Exploring the Dynamic Functional Landscape of Adenylate Kinase Modulated by Substrates

    Wang, Yong, Gan, L., Wang, E. & Wang, J., 2013, In: Journal of Chemical Theory and Computation. 9, 1, p. 84-95 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Multiscaled exploration of coupled folding and binding of an intrinsically disordered molecular recognition element in measles virus nucleoprotein

    Wang, Yong, Chu, X., Longhi, S., Roche, P., Han, W., Wang, E. & Wang, J., 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 40, p. E3743-E3752 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. 2012

  48. Exploration of Multi-State Conformational Dynamics and Underlying Global Functional Landscape of Maltose Binding Protein

    Wang, Yong, Tang, C., Wang, E. & Wang, J., 2012, In: P L o S Computational Biology (Online). 8, 4, 15 p., e1002471.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Importance of Electrostatic Interactions in the Association of Intrinsically Disordered Histone Chaperone Chz1 and Histone H2A.Z-H2B

    Chu, X., Wang, Yong, Gan, L., Bai, Y., Han, W., Wang, E. & Wang, J., 2012, In: P L o S Computational Biology (Online). 8, 7, 11 p., e1002608.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Multidomain Protein Solves the Folding Problem by Multifunnel Combined Landscape: Theoretical Investigation of a Y-Family DNA Polymerase

    Wang, Yong, Chu, X., Suo, Z., Wang, E. & Wang, J., 2012, In: Journal of the American Chemical Society. 134, 33, p. 13755-13764 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. 2011

  52. Multi-scaled explorations of binding-induced folding of intrinsically disordered protein inhibitor IA3 to its target enzyme

    Wang, J., Wang, Yong, Chu, X., Hagen, S. J., Han, W. & Wang, E., 2011, In: P L o S Computational Biology (Online). 7, 4, 12 p., e1001118.

    Research output: Contribution to journal › Journal article › Research › peer-review

ID: 45779122