Ying Liu
Associate Professor - Promotion Programme
Molecular Aging Program
Blegdamsvej 3, 2200 København N.
- 2002
- Published
Physical and transcript map of the region between D6S264 and D6S149 on chromosome 6q27, the minimal region of allele loss in sporadic epithelial ovarian cancer
Liu, Ying, Emilion, G., Mungall, A. J., Dunham, I., Beck, S., Le Meuth-Metzinger, V. G., Shelling, A. N., Charnock, F. M. L. & Ganesan, T. S., 17 Jan 2002, In: Oncogene. 21, 3, p. 387-99 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tumour suppressor genes in sporadic epithelial ovarian cancer
Liu, Ying & Ganesan, T. S., 1 Mar 2002, In: Reproduction. 123, 3, p. 341-53 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The human homologue of unc-93 maps to chromosome 6q27 - characterisation and analysis in sporadic epithelial ovarian cancer
Liu, Ying, Dodds, P., Emilion, G., Mungall, A. J., Dunham, I., Beck, S., Wells, R. S., Charnock, F. M. L. & Ganesan, T. S., 15 Oct 2002, In: B M C Genetics. 3, p. 20Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
Carcinogenesis of Colorectal Cancer. In Cancer De Colon
Liu, Ying & Bodmer, W., 2004, In: Reto E Anus. p. 43-54 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
CDX1 is an important molecular mediator of Barrett's metaplasia
Wong, N. A. C. S., Wilding, J., Bartlett, S., Liu, Ying, Warren, B. F., Piris, J., Maynard, N., Marshall, R. & Bodmer, W. F., 24 May 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 21, p. 7565-70 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines
Liu, Ying & Bodmer, W. F., 24 Jan 2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 4, p. 976-81 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex changes and multiple forms of chromosomal instability in colorectal cancers
Gaasenbeek, M., Howarth, K., Rowan, A. J., Gorman, P. A., Jones, A., Chaplin, T., Liu, Ying, Bicknell, D., Davison, E. J., Fiegler, H., Carter, N. P., Roylance, R. R. & Tomlinson, I. P. M., 1 Apr 2006, In: Cancer Research. 66, 7, p. 3471-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
RPS6KA2, a putative tumour suppressor gene at 6q27 in sporadic epithelial ovarian cancer
Bignone, P. A., Lee, K. Y., Liu, Ying, Emilion, G., Finch, J., Soosay, A. E. R., Charnock, F. M. L., Beck, S., Dunham, I., Mungall, A. J. & Ganesan, T. S., 1 Feb 2007, In: Oncogene. 26, 5, p. 683-700 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Gastrointestinal differentiation marker Cytokeratin 20 is regulated by homeobox gene CDX1
Chan, C. W. M., Wong, N. A., Liu, Ying, Bicknell, D., Turley, H., Hollins, L., Miller, C. J., Wilding, J. L. & Bodmer, W. F., 10 Feb 2009, In: Proceedings of the National Academy of Sciences USA (PNAS). 106, 6, p. 1936-41 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutations in the AXIN1 gene in advanced prostate cancer
Yardy, G. W., Bicknell, D. C., Wilding, J. L., Bartlett, S., Liu, Ying, Winney, B., Turner, G. D. H., Brewster, S. F. & Bodmer, W. F., 1 Sep 2009, In: European Urology Supplements. 56, 3, p. 486-94 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
5-Fluorouracil response in a large panel of colorectal cancer cell lines is associated with mismatch repair deficiency
Bracht, K., Nicholls, A. M., Liu, Ying & Bodmer, W. F., 27 Jul 2010, In: British Journal of Cancer Management. 103, 3, p. 340-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Replication error deficient and proficient colorectal cancer gene expression differences caused by 3'UTR polyT sequence deletions
Wilding, J. L., McGowan, S., Liu, Ying & Bodmer, W. F., 7 Dec 2010, In: PNAS Early Edition. 107, 49, p. 21058-63 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
MUS81 promotes common fragile site expression
Ying, S., Minocherhomji, S., Chan, K. L., Palmai-Pallag, T., Chu, W. K., Wass, T. A., Mankouri, H. W., Liu, Ying & Hickson, Ian David, Aug 2013, In: Nature Cell Biology. 15, 8, p. 1001-1007 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PICH: A DNA Translocase Specially Adapted for Processing Anaphase Bridge DNA
Biebricher, A., Hirano, S., Enzlin, J., Wiechens, N., Streicher, W., Huttner, D., Wang, L., Nigg, E., Owen-Hughes, T., Liu, Ying, Peterman, E., Wuite, G. & Hickson, Ian David, 12 Sep 2013, In: Molecular Cell. 51, 5, p. 691-701 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FBH1 helicase disrupts RAD51 filaments in vitro and modulates homologous recombination in mammalian cells
Simandlova, J., Zagelbaum, J., Payne, M. J., Chu, W. K., Shevelev, I., Hanada, K., Chatterjee, S., Reid, D. A., Liu, Ying, Janscak, P., Rothenberg, E. & Hickson, Ian David, 22 Nov 2013, In: The Journal of Biological Chemistry. 288, 47, p. 34168-80 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
The origins and processing of ultra fine anaphase DNA bridges
Liu, Ying, Nielsen, Christian Friberg, Yao, Q. & Hickson, Ian David, 30 Apr 2014, In: Current Opinion in Genetics & Development. 26C, p. 1-5 5 p.Research output: Contribution to journal › Review › Research › peer-review
- 2015
- Published
Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes
Newman, J. A., Savitsky, P., Allerston, C. K., Bizard, A. H., Özer, Ö., Sarlós, K., Liu, Ying, Pardon, E., Steyaert, J., Hickson, Ian David & Gileadi, O., 2015, In: Nucleic Acids Research. 43, 10, p. 5221-35 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PICH promotes sister chromatid disjunction and co-operates with topoisomerase II in mitosis
Nielsen, Christian Friberg, Huttner, D., Bizard, A. H., Hirano, S., Li, T., Palmai-Pallag, T., Bjerregaard, Victoria Alexandra, Liu, Ying, Nigg, E. A., Wang, L. H. & Hickson, Ian David, 2015, In: Nature Communications. 6, 15 p., 8962.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of SUMO2 Target Proteins by the Proteasome in Human Cells Exposed to Replication Stress
Bursomanno, S., McGouran, J. F., Kessler, B. M., Hickson, Ian David & Liu, Ying, 2015, In: Journal of Proteome Research. 14, 4, p. 1687-99 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells
Bursomanno, S., Beli, P., Khan, A. M., Minocherhomji, S., Wagner, S. A., Bekker-Jensen, Simon Holst, Mailand, Niels, Choudhary, Chunaram, Hickson, Ian David & Liu, Ying, Jan 2015, In: DNA Repair. 25, p. 84-96 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Replication stress activates DNA repair synthesis in mitosis
Minocherhomji, S., Ying, S., Bjerregaard, Victoria Alexandra, Bursomanno, S., Aleliunaite, A., Wu, Wei, Mankouri, H. W., Shen, H., Liu, Ying & Hickson, Ian David, 10 Dec 2015, In: Nature. 528, 7581, p. 286-90 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- 2016
- Published
Rad54 and Mus81 cooperation promotes DNA damage repair and restrains chromosome missegregation
Ghamrasni, S. E., Cardoso, R., Li, L., Guturi, K. K. N., Bjerregaard, Victoria Alexandra, Liu, Ying, Venkatesan, S., Hande, M. P., Henderson, J. T., Sanchez, O., Hickson, Ian David, Hakem, A. & Hakem, R., 15 Sep 2016, In: Oncogene. 35, 37, p. 4836-4845 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Biochemical and Mass Spectrometry-Based Approaches to Profile SUMOylation in Human Cells
Kessler, B. M., Bursomanno, S., McGouran, J. F., Hickson, Ian David & Liu, Ying, 2017, Activity-Based Proteomics: Methods and Protocols. Overkleeft, H. S. & Florea, B. I. (eds.). Humana Press, Vol. 1491. p. 131-144 14 p. (Methods in Molecular Biology, Vol. 1491).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Potential biomarkers of DNA replication stress in cancer
Ren, L., Chen, L., Wu, Wei, Garribba, L., Tian, H., Liu, Z., Vogel, Ivan, Li, C., Hickson, Ian David & Liu, Ying, 2017, In: OncoTarget. 8, 23, p. 36996-37008 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Folate deficiency drives mitotic missegregation of the human FRAXA locus
Bjerregaard, Victoria Alexandra, Garribba, L., McMurray, C. T., Hickson, Ian David & Liu, Ying, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 51, p. 13003-13008 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human cancer cells utilize mitotic DNA synthesis to resist replication stress at telomeres regardless of their telomere maintenance mechanism
Özer, Ö., Bhowmick, Rahul, Liu, Ying & Hickson, Ian David, 2018, In: OncoTarget. 9, 22, p. 15836-15846 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inducing and Detecting Mitotic DNA Synthesis at Difficult-to-Replicate Loci
Garribba, L., Wu, Wei, Özer, Ö., Bhowmick, Rahul, Hickson, Ian David & Liu, Ying, 2018, Methods in Enzymology: Mechanisms of DNA Recombination and Genome Rearrangements: Intersection between Homologous Recombination, DNA Replication and DNA Repair. Spies, M. & Malkova, A. (eds.). Elsevier, Vol. 601. p. 45-58 14 p. (Methods in Enzymology; No. 601).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
The Detection and Analysis of Chromosome Fragile Sites
Bjerregaard, Victoria Alexandra, Özer, Ö., Hickson, Ian David & Liu, Ying, 2018, Genome Instability: Methods and Protocols. Springer, Vol. 1672. p. 471-482 12 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 2019
- Published
Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability
Pladevall Morera, David, Munk, S., Ingham, Andreas, Garribba, L., Albers, E., Liu, Ying, Olsen, Jesper Velgaard & Lopez-Contreras, Andres, 2019, In: Nucleic Acids Research. 47, 15, p. 8004-8018 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The RIF1-PP1 Axis Controls Abscission Timing in Human Cells
Bhowmick, Rahul, Thakur, R. S., Venegas, A. B., Liu, Ying, Nilsson, Jakob, Barisic, Marin & Hickson, Ian David, 2019, In: Current Biology. 29, 7, p. 1232-1242.e5Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Folate stress induces SLX1- and RAD51-dependent mitotic DNA synthesis at the fragile X locus in human cells
Garribba, L., Bjerregaard, Victoria Alexandra, Gonçalves Dinis, M. M., Özer, Ö., Wu, Wei, Sakellariou, D., Pena-Diaz, J., Hickson, Ian David & Liu, Ying, 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 28, p. 16527-16536 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RTEL1 suppresses G-quadruplex-associated R-loops at difficult-to-replicate loci in the human genome
Wu, Wei, Bhowmick, Rahul, Vogel, Ivan, Özer, Ö., Ghisays, F., Thakur, R. S., Sanchez de Leon, E., Richter, P. H., Ren, L., Petrini, J. H., Hickson, Ian David & Liu, Ying, 2020, In: Nature Structural & Molecular Biology. 27, 5, p. 424-437 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Replication Stress Induces ATR/CHK1-Dependent Nonrandom Segregation of Damaged Chromosomes
Xing, M., Zhang, F., Liao, H., Chen, S., Che, L., Wang, X., Bao, Z., Ji, F., Chen, G., Zhang, H., Li, W., Chen, Z., Liu, Ying, Hickson, Ian David, Shen, H. & Ying, S., 2020, In: Molecular Cell. 78, 4, p. 714-724.e5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The prevention and resolution of DNA replication–transcription conflicts in eukaryotic cells
Wu, Wei, Hickson, Ian David & Liu, Ying, 2020, In: Genome Instability & Disease. 1, 3, p. 114–128 15 p.Research output: Contribution to journal › Review › Research › peer-review
- 2021
- Published
Folate Deficiency Triggers the Abnormal Segregation of a Region With Large Cluster of CG-Rich Trinucleotide Repeats on Human Chromosome 2
Garribba, L., Vogel, Ivan, Lerdrup, Mads, Gonçalves Dinis, M. M., Ren, L. & Liu, Ying, 2021, In: Frontiers in Genetics. 12, 695124.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Nonlinear mechanics of human mitotic chromosomes
Meijering, A. E. C., Sarlós, K., Nielsen, Christian Friberg, Witt, H., Harju, J., Kerklingh, E., Haasnoot, G. H., Bizard, A. H., Heller, I., Broedersz, C. P., Liu, Ying, Peterman, E. J. G., Hickson, Ian David & Wuite, G. J. L., 2022, In: Nature. p. 545–550Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RAD51 protects human cells from transcription-replication conflicts
Bhowmick, Rahul, Lerdrup, Mads, Gadi, Sampath Amitash, Rossetti, G. G., Singh, Manika Indrajit, Liu, Ying, Halazonetis, T. D. & Hickson, Ian David, 2022, In: Molecular Cell. 82, 18, p. 3366-3381.e9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SCAI promotes error-free repair of DNA interstrand crosslinks via the Fanconi anemia pathway
Schubert, Lisa, Hendriks, Ivo Alexander, Hertz, Emil Peter Thrane, Wu, Wei, Sellés Baiget, Selene, Hoffmann, Saskia, Bagge, Keerthana Stine Viswalingam, Gallina, I., Pentakota, S., Benedict, Bente, Johansen, Joachim, Apelt, K., Luijsterburg, M. S., Rasmussen, Simon, Lisby, Michael, Liu, Ying, Nielsen, Michael Lund, Mailand, Niels & Duxin, Julien, 2022, In: EMBO Reports. 23, 4, 20 p., e53639.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Completing genome replication outside of S phase
Bhowmick, Rahul, Hickson, Ian David & Liu, Ying, 2023, In: Molecular Cell. 83, 20, p. 3596-3607 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Mitotic DNA synthesis in response to replication stress requires the sequential action of DNA polymerases zeta and delta in human cells
Wu, Wei, Barwacz, Szymon Aleksander, Bhowmick, Rahul, Lundgaard, Katrine, Gonçalves Dinis, M. M., Clausen, Malgorzata, Kanemaki, M. T. & Liu, Ying, 2023, In: Nature Communications. 14, 1, 706.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 22618792
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Potential biomarkers of DNA replication stress in cancer
Research output: Contribution to journal › Journal article › Research › peer-review
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Folate deficiency drives mitotic missegregation of the human FRAXA locus
Research output: Contribution to journal › Journal article › Research › peer-review
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107
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Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability
Research output: Contribution to journal › Journal article › Research › peer-review
Published