Vilhelm Bohr

Vilhelm Bohr

Affiliate professor

Member of:

  • Web: Center for Healthy Aging

  • Web Track 3: Individualized health


  1. Published

    Increased deoxythymidine triphosphate levels is a feature of relative cognitive decline

    Madsen, Claus Desler, Frederiksen, J. H., Olsen, M. N. A., Maynard, S., Keijzers, Guido, Fagerlund, B., Mortensen, Erik Lykke, Osler, Merete, Lauritzen, Martin, Bohr, Vilhelm & Rasmussen, Lene Juel, Nov 2015, In : Mitochondrion. 25, p. 34-7 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Interaction between RECQL4 and OGG1 promotes repair of oxidative base lesion 8-oxoG and is regulated by SIRT1 deacetylase

    Duan, Shunlei, Han, Xuerui, Akbari, Mansour, Croteau, D. L., Rasmussen, Lene Juel & Bohr, Vilhelm, 20 May 2020, In : Nucleic Acids Research. 45, 12, p. 6530–6546

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Lamin A/C promotes DNA base excision repair

    Maynard, S., Keijzers, Guido, Akbari, Mansour, Ben Ezra, Michael, Hall, A., Morevati, M., Scheibye-Knudsen, Morten, Gonzalo, S., Bartek, J. & Bohr, Vilhelm, 2019, In : Nucleic Acids Research. 47, 22, p. 11709–11728

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Loss of NEIL1 causes defects in olfactory function in mice

    Canugovi, C., Misiak, M., Scheibye-Knudsen, Morten, Croteau, D. L., Mattson, M. P. & Bohr, Vilhelm, 1 Feb 2015, In : Neurobiology of Aging. 36, 2, p. 1007-1012 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Metabolism, genomics, and DNA repair in the mouse aging liver

    Lebel, M., de Souza-Pinto, N. C. & Bohr, Vilhelm, 1 Jan 2011, In : Current Gerontology and Geriatrics Research. 2011, p. 859415

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Mitochondria and aging

    Prolla, T. A., Bohr, Vilhelm & de Souza-Pinto, N. C., Jul 2010, In : Mechanisms of Ageing and Development. 131, 7-8, p. 449-50 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Mitochondria in the signaling pathways that control longevity and health span

    Akbari, Mansour, Kirkwood, T. B. L. & Bohr, Vilhelm, 2019, In : Ageing Research Reviews. 54, 100940.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Mitochondrial DNA repair and association with aging--an update

    Diaz, R. G., Bohr, Vilhelm & Stevnsner, T. V., 1 Aug 2010, In : Experimental Gerontology. 45, 7-8, p. 478-88 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  9. Published

    Mitochondrial base excision repair assays

    Maynard, S., de Souza-Pinto, N. C., Scheibye-Knudsen, M. & Bohr, Vilhelm, 1 Aug 2010, In : Methods. 51, 4, p. 416-25 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  10. Published

    Mitochondrial base excision repair in mouse synaptosomes during normal aging and in a model of Alzheimer's disease

    Diaz, R. G., Weissman, L., Yang, J., Bohr, Vilhelm & Stevnsner, T. V., 12 Aug 2010, In : Neurobiology of Aging.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Mitochondrial helicases and mitochondrial genome maintenance

    de Souza-Pinto, N. C., Aamann, M. D., Kulikowicz, T., Stevnsner, T. V. & Bohr, Vilhelm, 2010, In : Mechanisms of Ageing and Development. 131, 7-8, p. 503-10 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Mitophagy and Alzheimer's Disease: Cellular and Molecular Mechanisms

    Kerr, J. S., Adriaanse, B. A., Greig, N. H., Mattson, M. P., Cader, M. Z., Bohr, Vilhelm & Fang, E. F., 2017, In : Trends in Neurosciences. 40, 3, p. 151-166 16 p.

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Mitophagy in neurodegeneration and aging

    Fivenson, E. M., Lautrup, S., Sun, N., Scheibye-Knudsen, Morten, Stevnsner, T., Nilsen, H., Bohr, Vilhelm & Fang, E. F., 2017, In : Neurochemistry International. 109, p. 202-209

    Research output: Contribution to journalReviewResearchpeer-review

  14. Published

    Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease

    Fang, E. F., Hou, Y., Palikaras, K., Adriaanse, B. A., Kerr, J. S., Yang, B., Lautrup, S., Hasan-Olive, M. M., Caponio, D., Dan, X., Rocktäschel, P., Croteau, D. L., Akbari, Mansour, Greig, N. H., Fladby, T., Nilsen, H., Cader, M. Z., Mattson, M. P., Tavernarakis, N. & Bohr, Vilhelm, 2019, In : Nature Neuroscience. 22, p. 401-412

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Modulation of DNA base excision repair during neuronal differentiation

    Sykora, P., Yang, J., Ferrarelli, L. K., Tian, J., Tadokoro, T., Kulkarni, A., Weissman, L., Keijzers, Guido, Wilson, D. M., Mattson, M. P. & Bohr, Vilhelm, Jul 2013, In : Neurobiology of Aging. 34, 7, p. 1717-27 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    NAD(+) Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair

    Fang, E. F., Kassahun, H., Croteau, D. L., Scheibye-Knudsen, Morten, Marosi, K., Lu, H., Shamanna, R. A., Kalyanasundaram, S., Bollineni, R. C., Wilson, M. A., Iser, W. B., Wollman, B. N., Morevati, M., Li, J., Kerr, J. S., Lu, Q., Waltz, T. B., Tian, J., Sinclair, D. A., Mattson, M. P., Nilsen, H. & Bohr, Vilhelm, 11 Oct 2016, In : Cell Metabolism. 24, 4, p. 566-581 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome

    Fang, E. F., Hou, Y., Lautrup, S., Jensen, M. B., Yang, B., SenGupta, T., Caponio, D., Khezri, R., Demarest, T. G., Aman, Y., Figueroa, D., Morevati, M., Lee, H., Kato, H., Kassahun, H., Lee, J., Filippelli, D., Okur, M. N., Mangerich, A., Croteau, D. L., Maezawa, Y., Lyssiotis, C. A., Tao, J., Yokote, K., Rusten, T. E., Mattson, M. P., Jasper, H., Nilsen, H. & Bohr, Vilhelm, 2019, In : Nature Communications. 10, 1, 18 p., 5284.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    NAD+ in Aging: Molecular Mechanisms and Translational Implications

    Fang, E. F., Lautrup, S., Hou, Y., Demarest, T. G., Croteau, D. L., Mattson, M. P. & Bohr, Vilhelm, 2017, In : Trends in Molecular Medicine. 23, 10, p. 899-916 18 p.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published

    NAD+ supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency

    Hou, Y., Lautrup, S., Cordonnier, S., Wang, Y., Croteau, D. L., Zavala, E., Zhang, Y., Moritoh, K., O’Connell, J. F., Baptiste, B. A., Stevnsner, T. V., Mattson, M. P. & Bohr, Vilhelm, 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 8, p. E1876-E1885

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    NEIL1 stimulates neurogenesis and suppresses neuroinflammation after stress

    Yang, B., Figueroa, D. M., Hou, Y., Babbar, M., Baringer, S. L., Croteau, D. L. & Bohr, Vilhelm, 2019, In : Free Radical Biology and Medicine. 141, p. 47-58 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Negative Regulation of STAT3 Protein-mediated Cellular Respiration by SIRT1 Protein

    Bernier, M., Paul, R. K., Martin-Montalvo, A., Scheibye-Knudsen, M., Song, S., He, H., Armour, S. M., Hubbard, B. P., Bohr, Vilhelm, Wang, L., Zong, Y., Sinclair, D. A. & de Cabo, R., 3 Jun 2011, In : The Journal of Biological Chemistry. 286, 22, p. 19270-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Neurons efficiently repair glutamate-induced oxidative DNA damage by a process involving CREB-mediated up-regulation of apurinic endonuclease 1

    Yang, J., Tadokoro, T., Keijzers, Guido, Mattson, M. P. & Bohr, Vilhelm, 2010, In : Journal of Biological Chemistry. 285, 36, p. 28191-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Non-B DNA-forming sequences and WRN deficiency independently increase the frequency of base substitution in human cells

    Bacolla, A., Wang, G., Jain, A., Chuzhanova, N. A., Cer, R. Z., Collins, J. R., Cooper, D. N., Bohr, Vilhelm & Vasquez, K. M., 25 Mar 2011, In : The Journal of Biological Chemistry. 286, 12, p. 10017-26 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Nuclear DNA damage signalling to mitochondria in ageing

    Fang, E. F., Scheibye-Knudsen, Morten, Chua, K. F., Mattson, M. P., Croteau, D. L. & Bohr, Vilhelm, May 2016, In : Nature Reviews. Molecular Cell Biology. 17, 5, p. 308-321 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Nutrition and aging

    Cheng, W., Bohr, Vilhelm & de Cabo, R., 1 Apr 2010, In : Mechanisms of Ageing and Development. 131, 4, p. 223-4 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 4975983