Thomas Werge
Clinical Professor
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Genetic disposition towards educational attainment and intelligence test performance predict voter turnout
Aaroe, L., Appadurai, V., Hansen, Kasper Møller, Schork, A. J., Werge, Thomas, Mors, O., Borglum, A. D., Hougaard, D. M., Nordentoft, Merete, Mortensen, P. B., Thompson, W. K., Buil, A., Agerbo, E. & Petersen, M. B., 2021, In: Nature Human Behavior. 5, 2, p. 281-291 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A comprehensive family-based replication study of schizophrenia genes
Aberg, K. A., Liu, Y., Bukszár, J., McClay, J. L., Khachane, A. N., Andreassen, O. A., Blackwood, D., Corvin, A., Djurovic, S., Gurling, H., Ophoff, R., Pato, C. N., Pato, M. T., Riley, B., Webb, T., Kendler, K., O'Donovan, M., Craddock, N., Kirov, G., Owen, M. & 7 others, , 1 Feb 2013, In: JAMA psychiatry (Chicago, Ill.). 70, 2, p. 1-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Risk of Early-Onset Depression Associated With Polygenic Liability, Parental Psychiatric History, and Socioeconomic Status
Agerbo, E., Trabjerg, B. B., Børglum, A. D., Schork, A. J., Vilhjálmsson, B. J., Pedersen, C. B., Hakulinen, C., Albiñana, C., Hougaard, D. M., Grove, J., McGrath, J. J., Bybjerg-Grauholm, J., Mors, O., Plana-Ripoll, O., Werge, Thomas, Wray, N. R., Mortensen, P. B. & Musliner, K. L., 2021, In: JAMA Psychiatry. 78, 4, p. 387-397 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses
Ahluwalia, T. S., Eliasen, A. U., Sevelsted, A., Pedersen, C-E. T., Stokholm, J., Chawes, B., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Sharma, A., Weiss, S. T., Evans, M. D., Jackson, D. J., Morin, A., Krogfelt, K. A., Schjørring, S., Mortensen, P. B., Hougaard, D. M. & 13 others, , 2020, In: Nature Communications. 11, 12 p., 6398.Research output: Contribution to journal › Journal article › Research › peer-review
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Multi-PGS enhances polygenic prediction by combining 937 polygenic scores
Albiñana, C., Zhu, Z., Schork, A. J., Ingason, A., Aschard, H., Brikell, I., Bulik, C. M., Petersen, L. V., Agerbo, E., Grove, J., Nordentoft, Merete, Hougaard, D. M., Werge, Thomas, Børglum, A. D., Mortensen, P. B., McGrath, J. J., Neale, B. M., Privé, F. & Vilhjálmsson, B. J., 2023, In: Nature Communications. 14, 11 p., 4702.Research output: Contribution to journal › Journal article › Research › peer-review
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Leveraging both individual-level genetic data and GWAS summary statistics increases polygenic prediction
Albiñana, C., Grove, J., McGrath, J. J., Agerbo, E., Wray, N. R., Bulik, C. M., Nordentoft, Merete, Hougaard, D. M., Werge, Thomas, Børglum, A. D., Mortensen, P. B., Privé, F. & Vilhjálmsson, B. J., 2021, In: American Journal of Human Genetics. 108, 6, p. 1001-1011 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic correlates of vitamin D-binding protein and 25-hydroxyvitamin D in neonatal dried blood spots
Albiñana, C., Zhu, Z., Borbye-Lorenzen, N., Boelt, S. G., Cohen, A. S., Skogstrand, K., Wray, N. R., Revez, J. A., Privé, F., Petersen, L. V., Bulik, C. M., Plana-Ripoll, O., Musliner, K. L., Agerbo, E., Børglum, A. D., Hougaard, D. M., Nordentoft, M., Werge, T., Mortensen, P. B., Vilhjálmsson, B. J. & 1 others, , 2023, In: Nature Communications. 14, 16 p., 852.Research output: Contribution to journal › Journal article › Research › peer-review
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Population Genomics of Stone Age Eurasia
Allentoft, M. E., Sikora, M., Refoyo-Martínez, A., Irving-Pease, E. K., Fischer, A., Barrie, W., Ingason, A., Stenderup, J., Sjögren, K-G., Pearson, A., Mota, B., Paulsson, B. S., Halgren, A., Macleod, R., Schjellerup Jørkov, M. L., Demeter, F., Novosolov, M., Sørensen, L., Nielsen, P-O., Henriksen, R. H. A. & 143 others, , 2022, p. 1-71, (bioRxiv).Research output: Working paper › Preprint › Research
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100 ancient genomes show repeated population turnovers in Neolithic Denmark
Allentoft, M. E., Sikora, M., Fischer, A., Sjögren, K-G., Ingason, A., Macleod, R., Rosengren, A., Schulz Paulsson, B., Jørkov, M. L. S., Novosolov, M., Stenderup, J., Price, T. D., Mortensen, M. F., Nielsen, A. B., Hede, M. U., Sørensen, L., Nielsen, P. O., Rasmussen, P., Jensen, T. Z. T., Refoyo-Martínez, A. & 48 others, , 2024, In: Nature. 625, 7994, p. 329-337 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Population genomics of post-glacial western Eurasia
Allentoft, M. E., Sikora, M., Refoyo-Martínez, A., Irving-Pease, E. K., Fischer, A., Barrie, W., Ingason, A., Stenderup, J., Sjögren, K-G., Pearson, A., da Mota, B. S., Paulsson, B. S., Halgren, A., Macleod, R., Jørkov, M. L. S., Demeter, F., Sørensen, L., Nielsen, P. O., Henriksen, R. A., Vimala, T. & 144 others, , 2024, In: Nature. 625, 7994, p. 301-311Research output: Contribution to journal › Journal article › Research › peer-review
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Deep Learning for Cross-Diagnostic Prediction of Mental Disorder Diagnosis and Prognosis Using Danish Nationwide Register and Genetic Data
Allesøe, R. L., Thompson, W. K., Bybjerg-Grauholm, J., Hougaard, D. M., Nordentoft, Merete, Werge, Thomas, Rasmussen, Simon & Benros, Michael Eriksen, 2023, In: JAMA Psychiatry. 80, 2, p. 146-155 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Deep learning-based integration of genetics with registry data for stratification of schizophrenia and depression
Allesøe, R. L., Nudel, R., Thompson, W. K., Wang, Y., Nordentoft, Merete, Børglum, A. D., Hougaard, D. M., Werge, Thomas, Rasmussen, Simon & Benros, Michael Eriksen, 2022, In: Science Advances. 8, 26, eabi7293.Research output: Contribution to journal › Journal article › Research › peer-review
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Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses
Als, T. D., Kurki, M. I., Grove, J., Voloudakis, G., Therrien, K., Tasanko, E., Nielsen, T. T., Naamanka, J., Veerapen, K., Levey, D. F., Bendl, J., Bybjerg-Grauholm, J., Zeng, B., Demontis, D., Rosengren, A., Athanasiadis, G., Bækved-Hansen, M., Qvist, P., Bragi Walters, G., Thorgeirsson, T. & 23 others, , 2023, In: Nature Medicine. 29, 7, p. 1832-1844 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of polygenic score for major depression with response to lithium in patients with bipolar disorder
Amare, A. T., Schubert, K. O., Hou, L., Clark, S. R., Papiol, S., Cearns, M., Heilbronner, U., Degenhardt, F., Tekola-Ayele, F., Hsu, Y. H., Shekhtman, T., Adli, M., Akula, N., Akiyama, K., Ardau, R., Arias, B., Aubry, J. M., Backlund, L., Bhattacharjee, A. K., Bellivier, F. & 46 others, , 2021, In: Molecular Psychiatry. 26, p. 2457–2470 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The adenosine A2A receptor agonist CGS 21680 exhibits antipsychotic-like activity in Cebus apella monkeys
Andersen, M. B., Fuxe, K., Werge, Thomas & Gerlach, J., 2002, In: Behavioural Pharmacology. 13, 8, p. 639-44 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The muscarinic M1/M4 receptor agonist xanomeline exhibits antipsychotic-like activity in Cebus apella monkeys
Andersen, M. B., Fink-Jensen, Anders, Peacock, L., Gerlach, J., Bymaster, F., Lundbaek, J. A. & Werge, Thomas, 2003, In: Neuropsychopharmacology. 28, 6, p. 1168-75 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antipsychotic-like effect of the muscarinic acetylcholine receptor agonist BuTAC in non-human primates
Andersen, M. B., Croy, C. H., Dencker, D., Werge, Thomas, Bymaster, F. P., Felder, C. C. & Fink-Jensen, Anders, 2015, In: PLOS ONE. 10, 4, p. 1-13 13 p., e0122722.Research output: Contribution to journal › Journal article › Research › peer-review
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Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders
Andlauer, T. F. M., Guzman-Parra, J., Streit, F., Strohmaier, J., González, M. J., Gil Flores, S., Cabaleiro Fabeiro, F. J., del Río Noriega, F., Perez, F. P., Haro González, J., Orozco Diaz, G., de Diego-Otero, Y., Moreno-Küstner, B., Auburger, G., Degenhardt, F., Heilmann-Heimbach, S., Herms, S., Hoffmann, P., Frank, J., Foo, J. C. & 26 others, , 2021, In: Molecular Psychiatry. 26, 4, p. 1286-1298 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate
Andreassen, O. A., Thompson, W. K., Schork, A. J., Ripke, S., Mattingsdal, M., Kelsoe, J. R., Kendler, K. S., O'Donovan, M. C., Rujescu, D., Werge, Thomas, Sklar, P., Roddey, J. C., Chen, C., McEvoy, L., Desikan, R. S., Djurovic, S., Dale, A. M. & Psychiatric Genomics Consortium (PGC), P. G. C. (., Apr 2013, In: P L o S Genetics (Online). 9, 4, p. e1003455Research output: Contribution to journal › Journal article › Research › peer-review
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Improved Detection of Common Variants Associated with Schizophrenia by Leveraging Pleiotropy with Cardiovascular-Disease Risk Factors
Andreassen, O. A., Djurovic, S., Thompson, W. K., Schork, A. J., Kendler, K. S., O'Donovan, M. C., Rujescu, D., Werge, Thomas, van de Bunt, M., Morris, A. P., McCarthy, M. I., Roddey, J. C., McEvoy, L. K., Desikan, R. S., Dale, A. M. & International Consortium for Blood Pressure GWAS, I. C. F. B. P. G., Feb 2013, In: American Journal of Human Genetics. 92, 2, p. 197-209 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dystrobrevin-binding protein 1 gene (DTNBP1) variants associated with cerebrospinal fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in healthy volunteers
Andreou, D., Saetre, P., Kähler, A. K., Werge, Thomas, Andreassen, O. A., Agartz, I., Sedvall, G. C., Hall, H., Terenius, L. & Jönsson, E. G., Sep 2011, In: European Neuropsychopharmacology. 21, 9, p. 700-4 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Tyrosine hydroxylase Val81Met polymorphism: lack of association with schizophrenia
Andreou, D., Saetre, P., Lundmark, P., Hansen, T., Timm, S., Melle, I., Djurovic, S., Andreassen, O. A., Werge, T., Hall, H., Agartz, I., Terenius, L., Jönsson, E. G., Andreou, D., Saetre, P., Lundmark, P., Hansen, T., Timm, S., Melle, I., Djurovic, S. & 6 others, , 2009, In: Psychiatric Genetics. 19, 5, p. 273-4 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Tryptophan hydroxylase gene 1 (TPH1) variants associated with cerebrospinal fluid 5-hydroxyindole acetic acid and homovanillic acid concentrations in healthy volunteers
Andreou, D., Saetre, P., Werge, Thomas, Andreassen, O. A., Agartz, I., Sedvall, G. C., Hall, H., Terenius, L. & Jönsson, E. G., 30 Dec 2010, In: Psychiatry Research. 180, 2-3, p. 63-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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D-amino acid oxidase activator gene (DAOA) variation affects cerebrospinal fluid homovanillic acid concentrations in healthy Caucasians
Andreou, D., Saetre, P., Werge, Thomas, Andreassen, O. A., Agartz, I., Sedvall, G. C., Hall, H., Terenius, L. & Jönsson, E. G., 2012, In: European Archives of Psychiatry and Clinical Neuroscience. 262, 7, p. 549-56 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
Anney, R. J. L., Ripke, S., Anttila, V., Grove, J., Holmans, P., Huang, H., Klei, L., Lee, P. H., Medland, S. E., Neale, B., Robinson, E., Weiss, L. A., Zwaigenbaum, L., Yu, T. W., Wittemeyer, K., Willsey, A. J., Wijsman, E. M., Werge, T., Wassink, T. H., Waltes, R. & 143 others, , 22 May 2017, In: Molecular Autism. 8, 17 p., 21.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1
Anttila, V., Stefansson, H., Kallela, M., Todt, U., Terwindt, G. M., Calafato, M. S., Nyholt, D. R., Dimas, A. S., Freilinger, T., Müller-Myhsok, B., Artto, V., Inouye, M., Alakurtti, K., Kaunisto, M. A., Hämäläinen, E., de Vries, B., Stam, A. H., Weller, C. M., Heinze, A., Heinze-Kuhn, K. & 31 others, , 1 Oct 2010, In: Nature Genetics. 42, 10, p. 869-73 5 p.Research output: Contribution to journal › Letter › Research › peer-review
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Analysis of shared heritability in common disorders of the brain
Anttila, V., Bulik-Sullivan, B., Finucane, H. K., Walters, R. K., Bras, J., Duncan, L., Escott-Price, V., Falcone, G. J., Gormley, P., Malik, R., Patsopoulos, N. A., Ripke, S., Wei, Z., Yu, D., Lee, P. H., Turley, P., Grenier-Boley, B., Chouraki, V., Kamatani, Y., Berr, C. & 557 others, , 2018, In: Science. 360, 6395, 40 p., eaap8757.Research output: Contribution to journal › Journal article › Research › peer-review
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Accuracy of haplotype estimation and whole genome imputation affects complex trait analyses in complex biobanks
Appadurai, V., Bybjerg-Grauholm, J., Krebs, M. D., Rosengren, A., Buil, A., Ingason, A., Mors, O., Børglum, A. D., Hougaard, D. M., Nordentoft, Merete, Mortensen, P. B., Delaneau, O., Werge, Thomas & Schork, A. J., 2023, In: Communications Biology . 6, 101.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder
Arnau-Soler, A., Adams, M. J., Generation Scotland, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Hayward, C., Thomson, P. A., Porteous, D., Campbell, A., Smith, B. H., Black, C., Padmanabhan, S., McIntosh, A. M., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Agerbo, E., Air, T. M. & 32 others, , 2018, In: PLOS ONE. 13, 12, p. 1-29 e0209160.Research output: Contribution to journal › Journal article › Research › peer-review
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A comprehensive map of genetic relationships among diagnostic categories based on 48.6 million relative pairs from the Danish genealogy
Athanasiadis, G., Meijsen, J. J., Helenius, D., Schork, A. J., Ingason, A., Thompson, W. K., Geschwind, D. H., Werge, Thomas & Buil, A., 2022, In: PNAS. 119, 6, 9 p., e2118688119.Research output: Contribution to journal › Journal article › Research › peer-review
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Links between cardiovascular disease and osteoporosis in postmenopausal women: serum lipids or atherosclerosis per se?
Bagger, Y. Z., Rasmussen, H. B., Alexandersen, P., Werge, Thomas, Christiansen, C., Tankó, L. B. & PERF study group, P. S. G., 2007, In: Osteoporosis International. 18, 4, p. 505-12 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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DanMAC5: a browser of aggregated sequence variants from 8,671 whole genome sequenced Danish individuals
Banasik, K., Møller, P. L., Techlo, T. R., Holm, P. C., Walters, G. B., Ingason, A., Rosengren, A., Rohde, P. D., Kogelman, L. J. A., Westergaard, D., Siggaard, T., Chmura, P. J., Chalmer, M. A., Magnússon, Ó., Þórisson, G., Stefánsson, H., Guðbjartsson, D. F., Stefánsson, K., Olesen, J., Winther, S. & 5 others, , 2023, In: BMC Genomic Data. 24, 1, 4 p., 30.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Genetic liability to posttraumatic stress disorder and its association with postpartum depression
Bang Madsen, K., Liu, X., Albiñana, C., Jóhann Vilhjálmsson, B., Agerbo, E., Mortensen, P. B., Hougaard, D. M., Nordentoft, Merete, Werge, Thomas, Mors, O., Børglum, A. D. & Munk-Olsen, T., 2023, In: Psychological Medicine. 53, 11, p. 1-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank
Barbu, M. C., Zeng, Y., Shen, X., Cox, S. R., Clarke, T., Gibson, J., Adams, M. J., Johnstone, M., Haley, C. S., Lawrie, S. M., Deary, I. J., Mcintosh, A. M., Whalley, H. C., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J. & 216 others, , 2019, In: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 4, 1, p. 91-100 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic risk scores for major psychiatric disorders and the risk of postpartum psychiatric disorders
Bauer, A. E., Liu, X., Byrne, E. M., Sullivan, P. F., Wray, N. R., Agerbo, E., Nyegaard, M., Grove, J., Musliner, K. L., Ingstrup, K. G., Johannsen, B. M. W., Mægbæk, M. L., Wang, Y., Nordentoft, M., Mors, O., Børglum, A. D., Werge, T., Hougaard, D. M., Mortensen, P. B., Munk-Olsen, T. & 1 others, , 11 Nov 2019, In: Translational Psychiatry. 9, 1, 13 p., 288.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth
Beaumont, R. N., Flatley, C., Vaudel, M., Wu, X., Chen, J., Moen, G. H., Skotte, L., Helgeland, Ø., Solé-Navais, P., Banasik, K., Albiñana, C., Ronkainen, J., Fadista, J., Stinson, S. E., Trajanoska, K., Wang, C. A., Westergaard, D., Srinivasan, S., Sánchez-Soriano, C., Bilbao, J. R. & 68 others, , 2023, In: Nature Genetics. 55, 11, p. 1807-1819 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis
Bell, S., Rigas, A. S., Magnusson, M. K., Ferkingstad, E., Allara, E., Bjornsdottir, G., Ramond, A., Sørensen, E., Halldorsson, G. H., Paul, D. S., Burgdorf, K. S., Eggertsson, H. P., Howson, J. M. M., Thørner, L. W., Kristmundsdottir, S., Astle, W. J., Erikstrup, C., Sigurdsson, J. K., Vuckovic, D., Dinh, K. M. & 31 others, , 2021, In: Communications Biology . 4, 1, 14 p., 156.Research output: Contribution to journal › Journal article › Research › peer-review
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GENOME-WIDE ASSOCIATION STUDY, HERITABILITY ESTIMATION AND POLYGENIC RISK ANALYSIS OF SUSCEPTIBILITY TO INFECTIONS IN 65,534 INDIVIDUALS WITH SEVERE MENTAL DISORDERS AND POPULATION CONTROLS. O4.6.
Benros, Michael Eriksen, Nudel, R., Wang, Y., Appadurai, V., Schork, A., Agerbo, E., Werge, Thomas, Nordentoft, Merete, Mortensen, P., Buil, A. & Thompson, W., 2018, In: Schizophrenia Bulletin. 44, Suppl. 1, p. S85 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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Genetic susceptibility factors for multiple chemical sensitivity revisited
Berg, N. D., Rasmussen, Henrik Berg, Linneberg, Allan René, Andersen, C. B., Fenger, M., Dirksen, A., Vesterhauge, S., Werge, Thomas, Elberling, J. & Berg, N. D., 1 Mar 2010, In: International Journal of Hygiene and Environmental Health. 213, 2, p. 131-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of AADAC Deletion and Gilles de la Tourette Syndrome in a Large European Cohort
Bertelsen, B., Stefánsson, H., Riff Jensen, L., Melchior, L., Debes, N. M., Groth, C., Skov, L., Werge, T., Karagiannidis, I., Tarnok, Z., Barta, C., Nagy, P., Farkas, L., Brøndum-Nielsen, K., Rizzo, R., Gulisano, M., Rujescu, D., Kiemeney, L. A., Tosato, S., Nawaz, M. S. & 14 others, , 1 Mar 2016, In: Biological Psychiatry. 79, 5, p. 383–391 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association Study of CHRNA7 Promoter Variants with Sensory and Sensorimotor Gating in Schizophrenia Patients and Healthy Controls: A Danish Case-Control Study
Bertelsen, B., Oranje, B., Melchior, L., Fagerlund, Birgitte, Werge, Thomas, Mikkelsen, Jens D., Tümer, Asuman Zeynep & Glenthøj, Birte Yding, Dec 2015, In: NeuroMolecular Medicine. 17, 4, p. 423-30 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness
Bigdeli, T. B., Ripke, S., Bacanu, S-A., Lee, S. H., Wray, N. R., Gejman, P. V., Rietschel, M., Cichon, S., St Clair, D., Corvin, A., Kirov, G., McQuillin, A., Gurling, H., Rujescu, D., Andreassen, O. A., Werge, T., Blackwood, D. H. R., Pato, C. N., Pato, M. T., Malhotra, A. K. & 4 others, , 2016, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 171, 2, p. 276-289 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology
Bjornsdottir, G., Stefansdottir, L., Thorleifsson, G., Sulem, P., Norland, K., Ferkingstad, E., Oddsson, A., Zink, F., Lund, S. H., Nawaz, M. S., Bragi Walters, G., Skuladottir, A. T., Gudjonsson, S. A., Einarsson, G., Halldorsson, G. H., Bjarnadottir, V., Sveinbjornsson, G., Helgadottir, A., Styrkarsdottir, U., Gudmundsson, L. J. & 26 others, , 2022, In: Nature Communications. 13, 13 p., 634.Research output: Contribution to journal › Journal article › Research › peer-review
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Rare variants with large effects provide functional insights into the pathology of migraine subtypes, with and without aura
Bjornsdottir, G., Chalmer, M. A., Stefansdottir, L., Skuladottir, A. T., Einarsson, G., Andresdottir, M., Beyter, D., Ferkingstad, E., Gretarsdottir, S., Halldorsson, B. V., Halldorsson, G. H., Helgadottir, A., Helgason, H., Hjorleifsson Eldjarn, G., Jonasdottir, A., Jonasdottir, A., Jonsdottir, I., Knowlton, K. U., Nadauld, L. D., Lund, S. H. & 30 others, , 2023, In: Nature Genetics. 55, 11, p. 1843-1853Research output: Contribution to journal › Journal article › Research › peer-review
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Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders
Blokland, G. A. M., Grove, J., Chen, C. Y., Cotsapas, C., Tobet, S., Handa, R., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M. & 35 others, , 2022, In: Biological Psychiatry. 91, 1, p. 107-117Research output: Contribution to journal › Journal article › Research › peer-review
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The correlates of neonatal complement component 3 and 4 protein concentrations with a focus on psychiatric and autoimmune disorders
Borbye-Lorenzen, N., Zhu, Z., Agerbo, E., Albiñana, C., Benros, M. E., Bian, B., Børglum, A. D., Bulik, C. M., Debost, J-C. P. G., Grove, J., Hougaard, D. M., McRae, A. F., Mors, O., Mortensen, P. B., Musliner, K. L., Nordentoft, M., Petersen, L. V., Privé, F., Sidorenko, J., Skogstrand, K. & 4 others, , 2023, In: Cell Genomics. 3, 12, 23 p., 100457.Research output: Contribution to journal › Journal article › Research › peer-review
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Cross-trait assortative mating is widespread and inflates genetic correlation estimates
Border, R., Athanasiadis, G., Buil Demur, Alfonso Alberto, Schork, A. J., Cai, N., Young, A. I., Werge, Thomas, Flint, J., Kendler, K. S., Sankararaman, S., Dahl, A. W. & Zaitlen, N. A., 2022, In: Science. 378, 6621, p. 754-761 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The substituted (S)-3-phenylpiperidine (-)-OSU6162 reduces apomorphine- and amphetamine-induced behaviour in Cebus apella monkeys
Brandt-Christensen, M., Andersen, M. B., Fink-Jensen, Anders, Werge, Thomas & Gerlach, J., 2006, In: Journal of Neural Transmission. 113, 1, p. 11-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic, Clinical, and Sociodemographic Factors Associated With Stimulant Treatment Outcomes in ADHD
Brikell, I., Wimberley, T., Albinana, C., Pedersen, E. M., Vilhjalmsson, B. J., Agerbo, E., Demontis, D., Borglum, A. D., Schork, A. J., LaBianca, S., Werge, Thomas, Mors, O., Hougaard, D. M., Thapar, A., Mortensen, P. B. & Dalsgaard, S., 2021, In: American Journal of Psychiatry. 178, 9, p. 854-864 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interplay of ADHD Polygenic Liability With Birth-Related, Somatic, and Psychosocial Factors in ADHD: A Nationwide Study
Brikell, I., Wimberley, T., Albiñana, C., Vilhjálmsson, B. J., Agerbo, E., Børglum, A. D., Demontis, D., Schork, A. J., LaBianca, S., Werge, Thomas, Hougaard, D. M., Nordentoft, Merete, Mors, O., Mortensen, P. B., Petersen, L. V. & Dalsgaard, S., 2023, In: The American Journal of Psychiatry. 180, 1, p. 73-88 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease
Bryois, J., Skene, N. G., Hansen, T. F., Kogelman, L. J. A., Watson, H. J., Liu, Z., Eating Disorders Working Group of the Psychiatric Genomics Consortium, Adan, R., Alfredsson, L., Ando, T., Andreassen, O., Baker, J., Bergen, A., Berrettini, W., Birgegård, A., Boden, J., Boehm, I., Boni, C., Boraska Perica, V., Brandt, H. & 44 others, , May 2020, In: Nature Genetics. 52, p. 482-493Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction between genetic polymorphisms and stressful life events in first episode depression
Bukh, Jens Otto Drachmann, Bock, C., Vinberg, Maj, Werge, Thomas, Gether, Ulrik, Kessing, Lars Vedel, Bukh, J. D., Bock, C., Vinberg, Maj, Werge, Thomas, Gether, U. & Kessing, Lars Vedel, 2009, In: Journal of Affective Disorders. 119, 1-3, p. 107-15 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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No interactions between genetic polymorphisms and stressful life events on outcome of antidepressant treatment
Bukh, Jens Otto Drachmann, Bock, C., Vinberg, Maj, Werge, Thomas, Gether, Ulrik, Kessing, Lars Vedel, Bukh, J. D., Bock, C., Vinberg, Maj, Werge, Thomas, Gether, U. & Kessing, Lars Vedel, 2009, In: European Neuropsychopharmacology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Digital questionnaire platform in the Danish Blood Donor Study
Burgdorf, K. S., Felsted, N., Mikkelsen, S., Nielsen, Maria Haahr, Thørner, L. W., Pedersen, Oluf Borbye, Sørensen, E., Nielsen, K. R., Bruun, M. T., Werge, Thomas, Erikstrup, C., Hansen, T. & Ullum, H., 12 Jul 2016, In: Computer Methods and Programs in Biomedicine. 135, p. 101-104 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
Burgdorf, K. S., Trabjerg, B., Giørtz Pedersen, M., Nissen, J., Banasik, K., Birger Pedersen, O., Sørensen, E., René Nielsen, K., Hørup Larsen, M., Erikstrup, C., Bruun-Rasmussen, P., Westergaard, D., Wegner Thørner, L., Hjalgrim, H., Martina Paarup, H., Brunak, S., Pedersen, C. B., Fuller Torrey, E., Werge, T., Bo Mortensen, P. & 2 others, , 2019, In: Brain, Behavior, and Immunity. 79, p. 152-158Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutation screening of the glutamate cysteine ligase modifier (GCLM) gene in patients with schizophrenia
Butticaz, C., Werge, Thomas, Beckmann, J. S., Cuénod, M., Do, K. Q., Rivolta, C., Butticaz, C., Werge, Thomas, Beckmann, J. S., Cuénod, M., Do, K. Q. & Rivolta, C., 2009, In: Psychiatric Genetics. 19, 4, p. 201-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Complex spatio-temporal distribution and genomic ancestry of mitochondrial DNA haplogroups in 24,216 Danes
Bybjerg-Grauholm, J., Hagen, C. M., Gonçalves, V. F., Bækvad-Hansen, M., Hansen, C. S., Hedley, P. L., Kanters, Jørgen K., Nielsen, J., Theisen, M., Mors, O., Kennedy, J., Als, T. D., Demur, A. B., Nordentoft, Merete, Børglum, A., Mortensen, P. B., Werge, Thomas, Hougaard, D. M. & Christiansen, M., 13 Dec 2018, In: PLoS ONE. 13, 12, 26 p., e0208829.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparing Copy Number Variations in a Danish Case Cohort of Individuals with Psychiatric Disorders
Calle Sánchez, X., Helenius, D., Bybjerg-Grauholm, J., Pedersen, C., Hougaard, D. M., Børglum, A. D., Nordentoft, Merete, Mors, O., Mortensen, P. B., Geschwind, D. H., Montalbano, S., Raznahan, A., Thompson, W. K., Ingason, A. & Werge, Thomas, 2022, In: JAMA Psychiatry. 79, 1, p. 59-69Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lack of association between two dopamine D2 receptor gene polymorphisms and schizophrenia
Caprini, S., Saetre, P., Melle, I., Djurovic, S., Andreassen, O. A., Skjødt, C., Doung, L., Werge, Thomas, Hall, H., Agartz, I., Terenius, L. & Jönsson, E. G., 1 Aug 2011, In: Psychiatric Genetics. 21, 4, p. 214-5 2 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
DNA-methylation and immunological response in medication overuse headache
Carlsen, L. N., Hansen, C. S., Kogelman, L. J. A., Werge, Thomas, Ullum, H., Bybjerg-Grauholm, J., Hansen, Thomas Folkmann & Jensen, Rigmor Højland, 2023, In: Cephalalgia. 43, 3, p. 1-11Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association study of nonsynonymous single nucleotide polymorphisms in schizophrenia
Carrera, N., Arrojo, M., Sanjuán, J., Ramos-Ríos, R., Paz, E., Suárez-Rama, J. J., Páramo, M., Agra, S., Brenlla, J., Martínez, S., Rivero, O., Collier, D. A., Palotie, A., Cichon, S., Nöthen, M. M., Rietschel, M., Rujescu, D., Stefansson, H., Steinberg, S., Sigurdsson, E. & 12 others, , 2012, In: Biological Psychiatry. 71, 2, p. 169-77 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia
Chen, X., Lee, G., Maher, B. S., Fanous, A. H., Chen, J., Zhao, Z., Guo, A., van den Oord, E., Sullivan, P. F., Shi, J., Levinson, D. F., Gejman, P. V., Sanders, A., Duan, J., Owen, M. J., Craddock, N. J., O'Donovan, M. C., Blackman, J., Lewis, D., Kirov, G. K. & 42 others, , 2011, In: Molecular Psychiatry. 16, 11, p. 1117-29 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assessment of bidirectional relationships between physical activity and depression among adults a 2-sample Mendelian randomization study
Choi, K. W., Chen, C. Y., Stein, M. B., Klimentidis, Y. C., Wang, M. J., Koenen, K. C., Smoller, J. W., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. T. F. & 31 others, , 2019, In: JAMA Psychiatry. 76, 4, p. 399-408 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of genetic constitution on migraine drug responses
Christensen, A. F., Esserlind, A., Werge, Thomas, Stefánsson, H., Stefánsson, K. & Olesen, Jes, Jun 2016, In: Cephalalgia : an international journal of headache. 36, 7, p. 624-39 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Experience of loneliness during the COVID-19 pandemic: a cross-sectional study of 50 968 adult Danes
Christoffersen, L. A. N., Helenius, D., Schwinn, M., Erikstrup, C., Hjalgrim, Henrik, Nissen, J., Banasik, Karina, Nielsen, K., Kaspersen, K. A., Dinh, K. M., Bruun, M. T., Ostrowski, Sisse Rye, Sækmose, S., Hansen, Thomas Folkmann, Werge, Thomas, Didriksen, M. & Pedersen, Ole Birger Vesterager, 2023, In: BMJ Open. 13, 4, 9 p., e064033.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls
Coleman, J. R. I., Gaspar, H. A., Bryois, J., Byrne, E. M., Forstner, A. J., Holmans, P. A., de Leeuw, C. A., Mattheisen, M., McQuillin, A., Whitehead Pavlides, J. M., Pers, T. H., Ripke, S., Stahl, E. A., Steinberg, S., Trubetskoy, V., Trzaskowski, M., Wang, Y., Abbott, L., Abdellaoui, A., Adams, M. J. & 32 others, , 2020, In: Biological Psychiatry. 88, 2, p. 169-184 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank
Coleman, J. R. I., Peyrot, W. J., Purves, K. L., Davis, K. A. S., Rayner, C., Choi, S. W., Hübel, C., Gaspar, H. A., Kan, C., Van der Auwera, S., Adams, M. J., Lyall, D. M., Choi, K. W., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J. & 31 others, , May 2020, In: Molecular Psychiatry. 25, p. 1430-1446Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic signature of the pathogenic 22q11.2 deletion identifies carriers and provides insight into systemic dysregulation
Courraud, J., Russo, F., Themudo, G. E., Laursen, S. S., Ingason, A., Hougaard, D. M., Cohen, A. S., Werge, Thomas & Ernst, M., 2023, In: Translational Psychiatry. 13, 7 p., 391.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study identifies 48 common genetic variants associated with handedness
Cuellar-Partida, G., Tung, J. Y., Eriksson, N., Albrecht, E., Aliev, F., Andreassen, O. A., Barroso, I., Beckmann, J. S., Boks, M. P., Boomsma, D. I., Boyd, H. A., Breteler, M. M. B., Campbell, H., Chasman, D. I., Cherkas, L. F., Davies, G., de Geus, E. J. C., Deary, I. J., Deloukas, P., Dick, D. M. & 98 others, , 2021, In: Nature Human Behaviour. 5, p. 59-70Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2019, In: Nature Communications. 10, 1, 18 p., 2548.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phenotype integration improves power and preserves specificity in biobank-based genetic studies of major depressive disorder
Dahl, A., Thompson, M., An, U., Krebs, M., Appadurai, V., Border, R., Bacanu, S., Werge, Thomas, Flint, J., Schork, A. J., Sankararaman, S., Kendler, K. S. & Cai, N., 2023, In: Nature Genetics. 55, 12, p. 2082-2093Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical association to FKBP5 rs1360780 in patients with depression
Dam, H., Buch, J. O. D., Nielsen, A. B., Weikop, Pia, Werge, Thomas & Jørgensen, M. B., 2019, In: Psychiatric Genetics. 29, 6, p. 220-225 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic and psychosocial influence on the association between early childhood infections and later psychiatric disorders
Debost, J. P. G., Thorsteinsson, E., Trabjerg, B., Benros, Michael Eriksen, Albiñana, C., Vilhjalmsson, B. J., Børglum, A., Mors, O., Werge, Thomas, Mortensen, P. B., Agerbo, E. & Vogdrup, L., 2022, In: Acta Psychiatrica Scandinavica. 146, 5, p. 406-419 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enhanced Maternal Origin of the 22q11.2 Deletion in Velocardiofacial and DiGeorge Syndromes
Delio, M., Guo, T., McDonald-McGinn, D. M., Zackai, E., Herman, S., Kaminetzky, M., Higgins, A. M., Coleman, K., Chow, C., Jalbrzikowski, M., Jarlbrzkowski, M., Bearden, C. E., Bailey, A., Vangkilde, A., Olsen, L., Olesen, C., Skovby, F., Werge, T. M., Templin, L., Busa, T. & 38 others, , 7 Mar 2013, In: American Journal of Human Genetics. 92, 3, p. 439-47 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder
ADHD Working Group of the Psychiatric Genomics Consortium (PGC), A. W. G. O. T. P. G. C. (., Jan 2019, In: Nature Genetics. 51, 1, p. 63-75 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of GRIN1 and GRIN2A-D With schizophrenia and genetic interaction with maternal herpes simplex virus-2 infection affecting disease risk
Demontis, D., Nyegaard, M., Buttenschøn, H. N., Hedemand, A., Pedersen, C. B., Grove, J., Zacharov, T. F., Nordentoft, Merete, Werge, Thomas, Hougaard, D. M., Sørensen, K. M., Yolken, R. H., Mors, O., Børglum, A. & Mortensen, P. B., 1 Dec 2011, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 156, 8, p. 913-22 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder
Demontis, D., Walters, R. K., Rajagopal, V. M., Waldman, I. D., Grove, J., Als, T. D., Dalsgaard, S., Ribasas, M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Werge, T., Nordentoft, M., Mors, O., Mortensen, P. B., Andreassen, O. A., Arranz, M. J., Banaschewski, T., Bau, C., Bellgrove, M., Biederman, J. & 31 others, , 2021, In: Nature Communications. 12, 576.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The gene encoding the melanin-concentrating hormone receptor 1 is associated with schizophrenia in a Danish case-control sample
Demontis, D., Nyegaard, M., Christensen, J. H., Severinsen, J. E., Hedemand, A., Hansen, T., Werge, Thomas, Mors, O. & Børglum, A., Apr 2012, In: Psychiatric Genetics. 22, 2, p. 62-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains: [Inkl. Correction]
Demontis, D., Walters, G. B., Athanasiadis, G., Walters, R., Therrien, K., Nielsen, T. T., Farajzadeh, L., Voloudakis, G., Bendl, J., Zeng, B., Zhang, W., Grove, J., Als, T. D., Duan, J., Satterstrom, F. K., Bybjerg-Grauholm, J., Bækved-Hansen, M., Gudmundsson, O. O., Magnusson, S. H., Baldursson, G. & 32 others, , 2023, In: Nature Genetics. 55, p. 198–208 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study implicates CHRNA2 in cannabis use disorder
Demontis, D., Rajagopal, V. M., Thorgeirsson, T. E., Als, T. D., Grove, J., Leppälä, K., Gudbjartsson, D. F., Pallesen, J., Hjorthøj, C., Reginsson, G. W., Tyrfingsson, T., Runarsdottir, V., Qvist, P., Christensen, J. H., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Huckins, L. M., Stahl, E. A., Timmermann, A., Agerbo, E. & 10 others, , 2019, In: Nature Neuroscience. 22, 7, p. 1066-1074Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: a polygenic risk score analysis
Derks, E. M., Vorstman, J. A. S., Ripke, S., Kahn, R. S., Ophoff, R. A., Schizophrenia Psychiatric Genomic Consortium, S. P. G. C., Hansen, T., Olsen, L., Jakobsen, K. D., Schmock, H., Skjødt, C., Rosengren, A., Høffding, L. K. E., Thygesen, J. H. & Werge, Thomas, 2012, In: P L o S One. 7, 6, p. e37852Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comorbidities to restless legs syndrome – results from the Danish blood donor study
Didriksen, Maria, Hansen, T., Rigas, A., Allen, R., Burchell, B., Thørner, L., Nielsen, K., Di Angelantonio, E., Nielsen, M., Jennum, Poul, Werge, Thomas, Erikstrup, C., Pedersen, O., Paarup, H., Hjalgrim, H., Bruun, M., Burgdorf, K., Sørensen, E. & Ullum, H., 2017, In: Sleep Medicine. 40, Supplement 1, p. E79 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Restless legs syndrome is associated with major comorbidities in a population of Danish blood donors
Didriksen, Maria, Allen, R. P., Burchell, B. J., Thørner, L. W., Rigas, A. S., Di Angelantonio, E., Nielsen, Maria Haahr, Jennum, Poul, Werge, Thomas, Erikstrup, C., Pedersen, Ole Birger Vesterager, Nielsen, K., Bruun, M. T., Burgdorf, K. S., Sørensen, E. & Ullum, H., May 2018, In: Sleep Medicine. 45, p. 124-131 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prevalence of restless legs syndrome and associated factors in an otherwise healthy population: results from the Danish Blood Donor Study
Didriksen, M., Rigas, A. S., Allen, R. P., Burchell, B. J., Di Angelantonio, E., Nielsen, Maria Haahr, Jennum, Poul, Werge, Thomas, Erikstrup, C., Pedersen, Ole Birger Vesterager, Bruun, M. T., Burgdorf, K. S., Sørensen, E. & Ullum, H., Aug 2017, In: Sleep Medicine. 36, p. 55-61 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of COVID-19 Pandemic on Sleep Quality, Stress Level and Health-Related Quality of Life - A Large Prospective Cohort Study on Adult Danes
Didriksen, Maria, Werge, Thomas, Nissen, J., Schwinn, M., Sørensen, E., Nielsen, K. R., Bruun, M. T., Banasik, Karina, Hansen, T. F., Erikstrup, C., Ostrowski, Sisse Rye, Jennum, Poul, Hjalgrim, Henrik, Ullum, H. & Pedersen, Ole Birger Vesterager, 2021, In: International Journal of Environmental Research and Public Health. 18, 14, 14 p., 7610.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Persistent gating deficit and increased sensitivity to NMDA receptor antagonism after puberty in a new mouse model of the human 22q11.2 microdeletion syndrome: A study in male mice
Didriksen, M., Fejgin, K., Nilsson, S. R. O., Birknow, M. R., Grayton, H. M., Larsen, P. H., Lauridsen, J. B., Nielsen, V., Celada, P., Santana, N., Kallunki, P., Christensen, K. V., Werge, Thomas, Stensbøl, T. B., Egebjerg, J., Gastambide, F., Artigas, F., Bastlund, J. F. & Nielsen, J., 2017, In: Journal of Psychiatry and Neuroscience. 42, 1, p. 48-58 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A possible association between schizophrenia and GRIK3 polymorphisms in a multicenter sample of Scandinavian origin (SCOPE)
Djurovic, S., Kähler, A. K., Kulle, B., Jönsson, E. G., Agartz, I., Le Hellard, S., Hall, H., Jakobsen, K. D., Hansen, T., Melle, I., Werge, T., Steen, V. M., Andreassen, O. A., Djurovic, S., Kähler, A. K., Kulle, B., Jönsson, E. G., Agartz, I., Le Hellard, S., Hall, H. & 6 others, , 2009, In: Schizophrenia Research. 107, 2-3, p. 242-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE)
Djurovic, S., Le Hellard, S., Kähler, A. K., Jönsson, E. G., Agartz, I., Steen, V. M., Hall, H., Wang, A. G., Rasmussen, H. B., Melle, I., Werge, T., Andreassen, O. A., Djurovic, S., Le Hellard, S., Kähler, A. K., Jönsson, E. G., Agartz, I., Steen, V. M., Hall, H., Wang, A. G. & 4 others, , 2009, In: Psychiatry Research. 168, 3, p. 256-8 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors
Docherty, A. R., Mullins, N., Ashley-Koch, A. E., Qin, X., Coleman, J. R. I., Shabalin, A., Kang, J. E., Murnyak, B., Wendt, F., Adams, M., Campos, A. I., DiBlasi, E., Fullerton, J. M., Kranzler, H. R., Bakian, A. V., Monson, E. T., Rentería, M. E., Walss-Bass, C., Andreassen, O. A., Behera, C. & 228 others, , 2023, In: American Journal of Psychiatry. 180, 10, p. 723-738 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Current advancements of modelling schizophrenia using patient-derived induced pluripotent stem cells
Dubonyte, Ugne, Asenjo-Martinez, A., Werge, Thomas, Lage, K. & Kirkeby, Agnete, 2022, In: Acta Neuropathologica Communications. 10, 1, 20 p., 183.Research output: Contribution to journal › Review › Research › peer-review
- Published
Mutations in NRXN1 in a family multiply affected with brain disorders: NRXN1 mutations and brain disorders
Duong, L., Klitten, L. L., Møller, R. S., Ingason, A., Jakobsen, K. D., Skjødt, C., Didriksen, M., Hjalgrim, H., Werge, Thomas & Tommerup, Niels, Apr 2012, In: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 159B, 3, p. 354-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two rare deletions upstream of the NRXN1 gene (2p16.3) affecting the non-coding mRNA AK127244 segregate with diverse psychopathological phenotypes in a family
Duong, L. T. T., Hoeffding, L. K., Petersen, K. B., Knudsen, C. D., Thygesen, J. H., Klitten, L. L., Tommerup, Niels, Ingason, A. & Werge, Thomas, Dec 2015, In: European Journal of Medical Genetics. 58, 12, p. 650-653 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altered limbic microstructure in antipsychotic-naïve first-episode schizophrenia patients and associations with the schizophrenia susceptibility gene ZNF804A
Ebdrup, B., Baare, W., Hansen, T., Rasmussen, H., Aggernæs, B., Werge, Thomas, Glenthøj, Birte Yding & Skimminge, A., 2011. 0 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Ancient genomes from Iceland reveal the making of a human population
Ebenesersdóttir, S. S., Sandoval Velasco, M., Gunnarsdóttir, E. D., Jagadeesan, A., Guðmundsdóttir, V. B., Thordardóttir, E. L., Einarsdóttir, M. S., Moore, K. H. S., Sigurðsson, Á., Magnusdóttir, D. N., Jonsson, H., Snorradóttir, S., Hovig, E., Møller, P., Kockum, I., Olsson, T., Alfredsson, L., Hansen, T. F., Werge, T., Cavalleri, G. L. & 10 others, , 2018, In: Science. 360, 6392, p. 1028-1032 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB
Eliasen, A. U., Pedersen, C. E. T., Rasmussen, M. A., Wang, N., Soverini, M., Fritz, A., Stokholm, J., Chawes, B. L., Morin, A., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Mortensen, P. B., Hougaard, D. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Mors, O., Nordentoft, M. & 14 others, , 2022, In: Journal of Allergy and Clinical Immunology. 150, 3, p. 622-630Research output: Contribution to journal › Journal article › Research › peer-review
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Association Between Childhood Green Space, Genetic Liability, and the Incidence of Schizophrenia
Engemann, K., Pedersen, C. B., Agerbo, E., Arge, L., Børglum, A. D., Erikstrup, C., Hertel, O., Hougaard, D. M., McGrath, J. J., Mors, O., Mortensen, P. B., Nordentoft, Merete, Sabel, C. E., Sigsgaard, T., Tsirogiannis, C., Vilhjálmsson, B. J., Werge, Thomas, Svenning, J. C. & Horsdal, H. T., 2020, In: Schizophrenia Bulletin. 46, 6, p. 1629-1637 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cohort Profile: The Danish Blood Donor Study
Erikstrup, C., Sørensen, E., Nielsen, K. R., Bruun, M. T., Petersen, M. S., Rostgaard, K., Thørner, L. W., Larsen, M., Mikkelsen, S., Dinh, K. M., Schwinn, M., Rigas, A. S., Didriksen, M., Dowsett, J., von Stemann, J. H., Brodersen, T., Paulsen, I. W., Hindhede, L., Sækmose, S. G., Kaspersen, K. A. & 10 others, , 2023, In: International Journal of Epidemiology. 52, 3, p. e162-e171 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study
Erlangsen, A., Appadurai, V., Wang, Y., Turecki, G., Mors, O., Werge, Thomas, Mortensen, P. B., Starnawska, A., Børglum, A. D., Schork, A., Nudel, R., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Hougaard, D. M., Thompson, W. K., Nordentoft, Merete & Agerbo, E., 2020, In: Molecular Psychiatry. 25, p. 2410–2421Research output: Contribution to journal › Journal article › Research › peer-review
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Gestational age-dependent development of the neonatal metabolome
Ernst, M., Rogers, S., Lausten-Thomsen, U., Björkbom, A., Laursen, S. S., Courraud, J., Borglum, A., Nordentoft, Merete, Werge, Thomas, Mortensen, P. B., Hougaard, D. M. & Cohen, A. S., 2021, In: Pediatric Research. 89, p. 1396–1404 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Gene-Based Analysis of Regionally Enriched Cortical Genes in GWAS Data Sets of Cognitive Traits and Psychiatric Disorders
Ersland, K. M., Christoforou, A., Stansberg, C., Espeseth, T., Mattheisen, M., Mattingsdal, M., Hardarson, G. A., Hansen, T., Fernandes, C. P. D., Giddaluru, S., Breuer, R., Strohmaier, J., Djurovic, S., Nöthen, M. M., Rietschel, M., Lundervold, A. J., Werge, T., Cichon, S., Andreassen, O. A., Reinvang, I. & 2 others, , 2012, In: P L o S One. 7, 2, p. e31687Research output: Contribution to journal › Journal article › Research › peer-review
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Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
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Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
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