Sam Trammell

Sam Trammell

Assistant Professor, Guest Researcher

ORCID: 0000-0002-5941-4094

Publication year:
All
1 - 33 out of 33Page size: 100
  1. 2024
  2. Published

    Control of NAD+ homeostasis by autophagic flux modulates mitochondrial and cardiac function

    Zhang, Q., Li, Z., Li, Q., Trammell, Sam, Schmidt, M. S., Pires, K. M., Cai, J., Zhang, Y., Kenny, H., Boudina, S., Brenner, C. & Abel, E. D., 2024, In: EMBO Journal. 43, 3, p. 362-390

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2023
  4. Published

    Clostridium scindens secretome suppresses virulence gene expression of Clostridioides difficile in a bile acid-independent manner

    Saenz, C., Fang, Q., Gnanasekaran, Thiyagarajan, Trammell, Sam, Buijink, Jesse A., Pisano, P., Wierer, M., Moens, F., Lengger, B., Brejnrod, A. & Arumugam, Mani, 2023, In: Microbiology Spectrum. 11, 5, p. 1-18 e0393322.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Identification of bile acid-CoA:amino acid N-acyltransferase as the hepatic N-acyl taurine synthase for polyunsaturated fatty acids

    Trammell, Sam, Gamon, Luke Francis, Gotfryd, K., Michler, Katja Thorøe, Alrehaili, B. D., Rix, I., Knop, Filip Krag, Gourdon, Pontus Emanuel, Lee, Y. K., Davies, Michael J., Gillum, M. P. & Grevengoed, Trisha Jean, 2023, In: Journal of Lipid Research. 64, 9, 9 p., 100361.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Oral supplementation of nicotinamide riboside alters intestinal microbial composition in rats and mice, but not humans

    Peluso, A. A., Lundgaard, A. T., Babaei, P., Mousovich-Neto, F., Rocha, A. L., Damgaard, M. V., Bak, E. G., Gnanasekaran, T., Dollerup, O. L., Trammell, S. A. J., Nielsen, T. S., Kern, T., Abild, C. B., Sulek, K., Ma, T., Gerhart-Hines, Z., Gillum, M. P., Arumugam, M., Ørskov, C., McCloskey, D. & 4 others, Jessen, N., Herrgård, M. J., Mori, M. A. S. & Treebak, Jonas Thue, 2023, In: npj Aging. 9, 21 p., 7.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. 2022
  8. Published

    Bile acid conjugation deficiency causes hypercholanemia, hyperphagia, islet dysfunction, and gut dysbiosis in mice

    Alrehaili, B. D., Lee, M., Takahashi, S., Novak, R., Rimal, B., Boehme, S., Trammell, Sam, Grevengoed, Trisha Jean, Kumar, D., Alnouti, Y., Chiti, K., Wang, X., Patterson, A. D., Chiang, J. Y. L., Gonzalez, F. J. & Lee, Y., 2022, In: Hepatology Communications. 6, 10, p. 2765-2780 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    FGF21 suppresses alcohol consumption through an amygdalo-striatal circuit

    Flippo, K. H., Trammell, Sam, Gillum, M. P., Aklan, I., Perez, M. B., Yavuz, Y., Smith, N. K., Jensen-Cody, S. O., Zhou, B., Claflin, K. E., Beierschmitt, A., Fink-Jensen, Anders, Knop, Filip Krag, Palmour, R. M., Grueter, B. A., Atasoy, D. & Potthoff, M. J., 2022, In: Cell Metabolism. 34, 2, p. 317-328.e6

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Fibroblast growth factor 21 is the main alcohol responsive peptide hormone in humans and individuals with alcohol use disorder exihibit increased plasma concentrations after alcohol intake

    Lanng, A., Gasbjerg, Lærke Smidt, Sucksdorff, A., Svenningsen, J., Trammell, Sam, Vilsbøll, Tina, Gillum, M. & Knop, Filip Krag, 2022, In: Journal of Hepatology. 77, S1, p. S121-S121 1 p., THU006.

    Research output: Contribution to journal › Conference abstract in journal › Research

  11. Published

    Opposing effects of chronic glucagon receptor agonism and antagonism on amino acids, hepatic gene expression, and alpha cells

    Elmelund, E., Galsgaard, Katrine Douglas, Johansen, C. D., Trammell, Sam, Billeschou, Anna, Winther-Sørensen, Marie, Dal, Jenna Elizabeth Hunt, Sorensen, Charlotte Mehlin, Kruse, Thomas, Lau, J. F., Grevengoed, Trisha Jean, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2022, In: iScience. 25, 11, 20 p., 105296.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Opposing roles of the entero-pancreatic hormone urocortin-3 in glucose metabolism in rats

    Grunddal, Kaare Villum, Trammell, Sam, Bæch-Laursen, C., Andersen, Daniel Bjørklund, Xu, S. F. S., Andersen, H., Gillum, M. P., Ghiasi, S. M., Novak, Ivana, Tyrberg, B., Li, C., Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul & Kuhre, Rune Ehrenreich, 2022, In: Diabetologia. 65, p. 1018–1031

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. 2021
  14. Published

    An abundant biliary fatty acid metabolite derived from dietary omega-3 polyunsaturated fatty acids regulates triglycerides

    Grevengoed, Trisha Jean, Trammell, Sam, Svenningsen, J. S., Makarov, M., Nielsen, Thomas Svava, Jacobsen, Jens Christian Brings, Calder, P. C., Migaud, M. E., Cravatt, B. & Gillum, M. P., 2021, In: Journal of Clinical Investigation. 131, 6, 12 p., e143861.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Hepatocyte-specific perturbation of NAD+ biosynthetic pathways in mice induces reversible nonalcoholic steatohepatitis-like phenotypes

    Dall, M., Hassing, Anna Skab, Niu, Lili, Nielsen, Thomas Svava, Ingerslev, L. R., Sulek, K., Trammell, Sam, Gillum, M. P., Barrès, Romain, Larsen, Steen, Poulsen, Steen Seier, Mann, Matthias, Ørskov, Cathrine & Treebak, Jonas Thue, 2021, In: Journal of Biological Chemistry. 297, 6, 26 p., 101388.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The Biochemical Pathways of Nicotinamide-Derived Pyridones

    Hayat, F., Sonavane, M., Makarov, M. V., Trammell, Sam, McPherson, P., Gassman, N. R. & Migaud, M. E., 2021, In: International Journal of Molecular Sciences. 22, 3, 28 p., 1145.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. 2020
  18. Published

    Bilio-enteric flow and plasma concentrations of bile acids after gastric bypass and sleeve gastrectomy

    Eiken, A., Fuglsang, S., Eiken, M., Svane, M. S., Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Hansen, S. H., Trammell, Sam, Svenningsen, J. S., Rehfeld, Jens Frederik, Bojsen-Møller, K. N., Jørgensen, N. B., Holst, Jens Juul, Madsbad, Sten, Madsen, J. L. & Dirkse, C., 2020, In: International Journal of Obesity. 44, p. 1872-1883

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity

    Heer, C. D., Sanderson, D. J., Voth, L. S., Alhammad, Y. M. O., Schmidt, M. S., Trammell, Sam, Perlman, S., Cohen, M. S., Fehr, A. R. & Brenner, C., 2020, In: Journal of Biological Chemistry. 295, 52, p. 17986-17996 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Fasting- and ghrelin-induced food intake is regulated by NAMPT in the hypothalamus

    de Guia, R. M., Hassing, Anna Skab, Skov, Louise Julie, Ratner, C., Plucinska, Kaja, Madsen, S., Diep, T. A., dela Cruz, Gelo, Trammell, Sam, Sustarsic, E. G., Emanuelli, Brice, Gillum, M. P., Gerhart-Hines, Zach, Holst, Birgitte & Treebak, Jonas Thue, 2020, In: Acta Physiologica. 228, 4

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis

    Winther-Sørensen, M., Galsgaard, K. D., Santos, A., Trammell, S. A. J., Sulek, K., Kuhre, R. E., Pedersen, J., Andersen, D. B., Hassing, A. S., Dall, M., Treebak, J. T., Gillum, M. P., Torekov, S. S., Windeløv, J. A., Hunt, J. E., Kjeldsen, S. A. S., Jepsen, S. L., Vasilopoulou, C. G., Knop, F. K., Ørskov, C. & 7 others, Werge, M. P., Bisgaard, Hanne Cathrine, Eriksen, P. L., Vilstrup, H., Gluud, Lise Lotte, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Molecular Metabolism. 42, 18 p., 101080.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Hepatic Bile Acid Reuptake in the Rat Depends on Bile Acid Conjugation but Not on Agonistic Properties towards FXR and TGR5

    Trammell, Sam, Svenningsen, J. S., Holst, Jens Juul, Gillum, M. P. & Kuhre, Rune Ehrenreich, 2020, In: Molecules. 25, 14 p., 2371.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. 2019
  24. Published

    Effects of Nicotinamide Riboside on Endocrine Pancreatic Function and Incretin Hormones in Nondiabetic Men With Obesity

    Dollerup, O. L., Trammell, Sam, Hartmann, Bolette, Holst, Jens Juul, Christensen, B., Møller, N., Gillum, M. P., Treebak, Jonas Thue & Jessen, N., 1 Nov 2019, In: The Journal of clinical endocrinology and metabolism. 104, 11, p. 5703-5714 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    N-acyl taurines are endogenous lipid messengers that improve glucose homeostasis

    Grevengoed, Trisha Jean, Trammell, Sam, McKinney, M. K., Petersen, N., Cardone, R. L., Svenningsen, J. S., Ogasawara, D., Nexøe-Larsen, C. C., Knop, Filip Krag, Schwartz, Thue W., Kibbey, R. G., Cravatt, B. F. & Gillum, M. P., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 49, p. 24770-24778

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Bile acids drive colonic secretion of glucagon-like-peptide 1 and peptide-YY in rodents

    Christiansen, Charlotte Bayer, Trammell, Sam, Albrechtsen, Nicolai Jacob Wewer, Schoonjans, K., Albrechtsen, Reidar, Gillum, M. P., Kuhre, Rune Ehrenreich & Holst, Jens Juul, 2019, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 316, 5, p. G574-G584 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Mitochondrial function in liver cells is resistant to perturbations in NAD+ salvage capacity

    Dall, M., Trammell, Sam, Asping, M., Hassing, Anna Skab, Agerholm, M., Vienberg, S. G., Gillum, M. P., Larsen, Steen & Treebak, Jonas Thue, 2019, In: The Journal of Biological Chemistry. 294, 36, p. 13304-13326 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    The chemistry of the vitamin B3 metabolome

    Makarov, M. V., Trammell, Sam & Migaud, M. E., 2019, In: Biochemical Society Transactions. 47, 1, p. 131-147

    Research output: Contribution to journal › Review › Research › peer-review

  29. 2018
  30. Published

    Divergent effects of resistance and endurance exercise on plasma bile acids, FGF19, and FGF21 in humans

    Morville, T., Sahl, Ronni Eg, Trammell, Sam, Svenningsen, J. S., Gillum, M. P., Helge, Jørn Wulff & Clemmensen, Christoffer, 2018, In: JCI Insight. 3, 15, p. 1-13 e122737.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    FGF21, a liver hormone that inhibits alcohol intake in mice, increases in human circulation after acute alcohol ingestion and sustained binge drinking at Oktoberfest

    Søberg, S., Andersen, E. S., Dalsgaard, N. B., Jarlhelt, I., Hansen, N. L., Hoffmann, N., Vilsbøll, Tina, Chenchar, A., Jensen, M., Grevengoed, Trisha Jean, Trammell, Sam, Knop, Filip Krag & Gillum, M. P., 2018, In: Molecular Metabolism. 11, p. 96-103 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Nicotinamide riboside preserves cardiac function in a mouse model of dilated cardiomyopathy

    Diguet, N., Trammell, Sam, Tannous, C., Deloux, R., Piquereau, J., Mougenot, N., Gouge, A., Gressette, M., Manoury, B., Blanc, J., Breton, M., Decaux, J. F., Lavery, G. G., Baczkó, I., Zoll, J., Garnier, A., Li, Z., Brenner, C. & Mericskay, M., 2018, In: Circulation. 137, 21, p. 2256-2273 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. 2017

  34. Discovery and characterization of novel nonsubstrate and substrate NAMPT inhibitors

    Wilsbacher, J. L., Cheng, M., Cheng, D., Trammell, S. A. J., Shi, Y., Guo, J., Koeniger, S. L., Kovar, P. J., He, Y., Selvaraju, S., Heyman, H. R., Sorensen, B. K., Clark, R. F., Hansen, T. M., Longenecker, K. L., Raich, D., Korepanova, A. V., Cepa, S., Towne, D. L., Abraham, V. C. & 13 others, Tang, H., Richardson, P. L., McLoughlin, S. M., Badagnani, I., Curtin, M. L., Michaelides, M. R., Maag, D., Buchanan, F. G., Chiang, G. G., Gao, W., Rosenberg, S. H., Brenner, C. & Tse, C., 2017, In: Molecular Cancer Therapeutics. 16, 7, p. 1236-1245 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. 2016
  36. Published

    NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells

    Ratajczak, J., Joffraud, M., Trammell, Sam, Ras, R., Canela, N., Boutant, M., Kulkarni, S. S., Rodrigues, M., Redpath, P., Migaud, M. E., Auwerx, J., Yanes, O., Brenner, C. & Cantó, C., 11 Oct 2016, In: Nature Communications. 7, 13103.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

    Trammell, Sam, Schmidt, M. S., Weidemann, B. J., Redpath, P., Jaksch, F., Dellinger, R. W., Li, Z., Abel, E. D., Migaud, M. E. & Brenner, C., 10 Oct 2016, In: Nature Communications. 7, 12948.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Nicotinamide riboside opposes type 2 diabetes and neuropathy in mice

    Trammell, Sam, Weidemann, B. J., Chadda, A., Yorek, M. S., Holmes, A., Coppey, L. J., Obrosov, A., Kardon, R. H., Yorek, M. A. & Brenner, C., 27 May 2016, In: Scientific Reports. 6, 26933.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Nicotinamide riboside is a major NAD+ precursor vitamin in cow milk

    Trammell, Sam, Y., L., Redpath, P., Migaud, M. E. & Brenner, C., 1 May 2016, In: Journal of Nutrition. 146, 5, p. 957-963 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. 2015
  41. Published

    NNMT: A Bad Actor in Fat Makes Good in Liver

    Trammell, Sam & Brenner, C., 4 Aug 2015, In: Cell Metabolism. 22, 2, p. 200-201 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  42. 2013

  43. Targeted, LCMS-based metabolomics for quantitative measurement of NAD+ metabolites

    Trammell, Sam & Brenner, C., 2013, In: Computational and Structural Biotechnology Journal. 4, 5, e201301012.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. 2012
  45. Published

    Novel synthetic route to the C-nucleoside, 2-deoxy benzamide riboside

    Midtkandal, R. R., Redpath, P., Trammell, Sam, MacDonald, S. J. F., Brenner, C. & Migaud, M. E., 15 Aug 2012, In: Bioorganic and Medicinal Chemistry Letters. 22, 16, p. 5204-5207 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

ID: 138358551