Pontus Emanuel Gourdon
Associate Professor
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Dynein regulates Kv7.4 channel trafficking from the cell membrane
van der Horst, Jennifer, Rognant, Salomé, Abbott, G. W., Ozhathil, Lijo Cherian, Hägglund, Per Mårten, Barrese, V., Chuang, Christine, Jespersen, Thomas, Davies, Michael J., Greenwood, I. A., Gourdon, Pontus Emanuel, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2021, In: Journal of General Physiology. 153, 3, 19 p., e202012760.Research output: Contribution to journal › Journal article › Research › peer-review
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Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function
Zhang, L., Simonsen, C., Zimova, L., Wang, Kaituo, Moparthi, L., Gaudet, R., Ekoff, M., Nilsson, G., Hellmich, U. A., Vlachova, V., Gourdon, Pontus Emanuel & Zygmunt, P. M., 2022, In: Nature Communications. 13, 1, 18 p., 7483.Research output: Contribution to journal › Journal article › Research › peer-review
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Isolation and Crystallization of the D156C Form of Optogenetic ChR2
Zhang, L., Wang, Kaituo, Ning, S., Pedersen, Per Amstrup, Duelli, A. S. & Gourdon, Pontus Emanuel, 2022, In: Cells. 11, 5, 11 p., 895.Research output: Contribution to journal › Journal article › Research › peer-review
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Purification of Functional Human TRP Channels Recombinantly Produced in Yeast
Zhang, L., Wang, Kaituo, Klærke, Dan Arne, Callø, Kirstine, Lowrey, L., Pedersen, Per Amstrup, Gourdon, Pontus Emanuel & Gotfryd, K., 2019, In: Cells. 8, 2, p. 1-20 148.Research output: Contribution to journal › Journal article › Research › peer-review
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The two-domain elevator-type mechanism of zinc-transporting ZIP proteins
Wiuf, A., Steffen, Jonas Hyld, Becares, E. R., Gronberg, C., Mahato, D. R., Rasmussen, Søren Gøgsig Faarup, Andersson, M., Croll, T., Gotfryd, K. & Gourdon, Pontus Emanuel, 2022, In: Science Advances. 8, 28, 13 p., 4331.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure and mechanism of Zn2+-transporting P-type ATPases
Wang, Kaituo, Sitsel, O., Meloni, G., Autzen, Henriette Elisabeth, Andersson, M., Klymchuk, T., Nielsen, A. M., Rees, D. C., Nissen, P. & Gourdon, Pontus Emanuel, 23 Oct 2014, In: Nature. 514, 7523, p. 518-22 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding
Wang, Kaituo, Dagil, Robert, Lavstsen, Thomas, Misra, S. K., Spliid, C. B., Wang, Yong, Gustavsson, Tobias, Sandoval, D. R., Vidal-Calvo, E. E., Choudhary, Swati, Agerbæk, Mette Ørskov, Lindorff-Larsen, Kresten, Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sharp, J. S., Clausen, Thomas Mandel, Gourdon, Pontus Emanuel & Salanti, Ali, 2021, In: Nature Communications. 12, 1, 10 p., 2956.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure of the human ClC-1 chloride channel
Wang, Kaituo, Preisler, Sarah Spruce, Zhang, L., Cui, Y., Missel, Julie Winkel, Grønberg, C., Gotfryd, K., Lindahl, E., Andersson, M., Callø, Kirstine, Egea, P. F., Klærke, Dan Arne, Pusch, M., Pedersen, Per Amstrup, Zhou, Z. H. & Gourdon, Pontus Emanuel, 2019, In: PLOS Biology. 17, 4, p. 1-20 e3000218.Research output: Contribution to journal › Journal article › Research › peer-review
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The role of water coordination in the pH-dependent gating of hAQP10
Truelsen, S. F., Missel, Julie Winkel, Gotfryd, K., Pedersen, Per Amstrup, Gourdon, Pontus Emanuel, Lindorff-Larsen, Kresten & Hélix-Nielsen, C., 2022, In: B B A - Biomembranes. 1864, 1, 13 p., 183809.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of bile acid-CoA:amino acid N-acyltransferase as the hepatic N-acyl taurine synthase for polyunsaturated fatty acids
Trammell, Sam, Gamon, Luke Francis, Gotfryd, K., Michler, Katja Thorøe, Alrehaili, B. D., Rix, I., Knop, Filip Krag, Gourdon, Pontus Emanuel, Lee, Y. K., Davies, Michael J., Gillum, M. P. & Grevengoed, Trisha Jean, 2023, In: Journal of Lipid Research. 64, 9, 9 p., 100361.Research output: Contribution to journal › Journal article › Research › peer-review
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Crystal structure of AcrB in complex with a single transmembrane subunit reveals another twist
Toernroth-Horsefield, S., Gourdon, Pontus Emanuel, Horsefield, R., Brive, L., Yamamoto, N., Mori, H., Snijder, A. & Neutze, R., Dec 2007, In: Structure. 15, 12, p. 1663-1673Research output: Contribution to journal › Journal article › Research › peer-review
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Assessing water permeability of aquaporins in a proteoliposome-based stopped-flow setup
Steffen, Jonas Hyld, Missel, Julie Winkel, Al-Jubair, T., Kitchen, P., Salman, M. M., Bill, R. M., Törnroth-Horsefield, S. & Gourdon, Pontus Emanuel, 2022, In: STAR Protocols. 3, 2, 11 p., 101312.Research output: Contribution to journal › Journal article › Research › peer-review
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Identifying Heterozipper β-Sheet in Twisted Amyloid Aggregation
Song, Y., Dai, B., Wang, Yong, Wang, Y., Liu, C., Gourdon, Pontus Emanuel, Liu, L., Wang, Kaituo & Dong, M., 2022, In: Nano Letters. 22, 9, p. 3707–3712Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of ATP7A missense mutants suggests a correlation between intracellular trafficking and severity of Menkes disease
Skjørringe, T., Pedersen, Per Amstrup, Thorborg, S. S., Nissen, P., Gourdon, Pontus Emanuel & Møller, L. B., 7 Apr 2017, In: Scientific Reports. 7, 18 p., 757.Research output: Contribution to journal › Journal article › Research › peer-review
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Crystallization of P-type ATPases by the High Lipid-Detergent (HiLiDe) Method
Sitsel, O., Wang, Kaituo, Liu, X. & Gourdon, Pontus Emanuel, 2016, P-Type ATPases: Methods and Protocols. Bublitz, M. (ed.). Springer, Vol. 1377. p. 413-420 8 p. (Methods in Molecular Biology, Vol. 1377).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Structure and Function of Cu(I)- and Zn(II)-ATPases
Sitsel, O., Grønberg, C., Autzen, Henriette Elisabeth, Wang, Kaituo, Meloni, G., Nissen, P. & Gourdon, Pontus Emanuel, 22 Sep 2015, In: Biochemistry. 54, 37, p. 5673-5683 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structural basis of ion uptake in copper-transporting P1B-type ATPases
Salustros, N., Gronberg, C., Abeyrathna, N. S., Lyu, Pin, Oradd, F., Wang, Kaituo, Andersson, M., Meloni, G. & Gourdon, Pontus Emanuel, 2022, In: Nature Communications. 13, 1, 11 p., 5121.Research output: Contribution to journal › Journal article › Research › peer-review
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Mechanisms of a Mycobacterium tuberculosis Active Peptide
Rao, K. U., Li, P., Welinder, C., Tenland, E., Gourdon, Pontus Emanuel, Sturegård, E., Ho, J. C. S. & Godaly, G., 2023, In: Pharmaceutics. 15, 2, 16 p., 540.Research output: Contribution to journal › Journal article › Research › peer-review
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Endothelial protein C receptor binding induces conformational changes to severe malaria-associated group A PfEMP1
Raghavan, Sai Sundar Rajan, Turner, Louise, Jensen, R. W., Johansen, Nicolai Tidemand, Jensen, D. S., Gourdon, Pontus Emanuel, Zhang, J., Wang, Y., Theander, Thor Grundtvig, Wang, Kaituo & Lavstsen, Thomas, 2023, In: Structure. 31, 10, p. 1174-1183.e4Research output: Contribution to journal › Journal article › Research › peer-review
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Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA
Raghavan, Sai Sundar Rajan, Dagil, Robert, Lopez-Perez, Mary, Conrad, J., Bassi, Maria Rosaria, Quintana Varon, Maria del Pilar, Choudhary, Swati, Gustavsson, Tobias, Wang, Yong, Gourdon, Pontus Emanuel, Ofori, M. F., Christensen, S. B., Minja, D. T. R., Schmiegelow, Christentze, Nielsen, Morten Agertoug, Barfod, Lea Klingenberg, Hviid, Lars, Salanti, Ali, Lavstsen, Thomas & Wang, Kaituo, 2022, In: PLoS Pathogens. 18, 11, e1010924.Research output: Contribution to journal › Journal article › Research › peer-review
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Saccharomyces cerevisiae as a superior host for overproduction of prokaryotic integral membrane proteins
Preisler, Sarah Spruce, Wiuf, A. D., Friis, M., Kjaergaard, L., Hurd, M., Becares, E. R., Nurup, C. N., Bjoerkskov, F. B., Szathmáry, Z., Gourdon, Pontus Emanuel, Callø, Kirstine, Klærke, Dan Arne, Gotfryd, K. & Pedersen, Per Amstrup, 2021, In: Current research in structural biology. 3, p. 51-71 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Initiating Heavy-atom Based Phasing by Multi-Dimensional Molecular Replacement
Pedersen, B. P., Gourdon, Pontus Emanuel, Liu, X., Karlsen, J. L. & Nissen, P., 28 Mar 2014, In: arXiv. p. 1-19 19 p.Research output: Contribution to journal › Journal article › Research
Initiating heavy-atom-based phasing by multi-dimensional molecular replacement
Pedersen, B. P., Gourdon, Pontus Emanuel, Liu, X., Karlsen, J. L. & Nissen, P., 1 Mar 2016, In: Acta crystallographica Section D: Structural biology . 72, 3, p. 440-445 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Copper binding leads to increased dynamics in the regulatory N-terminal domain of full-length human copper transporter ATP7B
Orädd, F., Steffen, Jonas Hyld, Gourdon, Pontus Emanuel & Andersson, M., 2022, In: PLOS Computational Biology. 18, 9 September, 21 p., e1010074.Research output: Contribution to journal › Journal article › Research › peer-review
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Crystal Structure of Na+, K+-ATPase in the Na+-Bound State
Nyblom, M., Poulsen, H., Gourdon, Pontus Emanuel, Reinhard, L., Andersson, M., Lindahl, E., Fedosova, N. & Nissen, P., 4 Oct 2013, In: Science. 342, 6154, p. 123-127Research output: Contribution to journal › Journal article › Research › peer-review
ID: 108586181
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A high-yield co-expression system for the purification of an intact drs2p-cdc50p lipid flippase complex, critically dependent on and stabilized by phosphatidylinositol-4-phosphate
Research output: Contribution to journal › Journal article › Research › peer-review
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534
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Purification and functional comparison of nine human Aquaporins produced in Saccharomyces cerevisiae for the purpose of biophysical characterization
Research output: Contribution to journal › Journal article › Research › peer-review
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186
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Structure of the human ClC-1 chloride channel
Research output: Contribution to journal › Journal article › Research › peer-review
Published