Maiken Nedergaard

Maiken Nedergaard

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    1. Published

      Cerebral Metabolic Changes During Sleep

      Aalling, Nadia, Nedergaard, Maiken & DiNuzzo, M., 1 Sep 2018, In: Current Neurology and Neuroscience Reports. 18, 9, 17 p., 57.

      Research output: Contribution to journal › Review › Research › peer-review

    2. Published

      Current Understanding of the Anatomy, Physiology, and Magnetic Resonance Imaging of Neurofluids: Update From the 2022 “ISMRM Imaging Neurofluids Study group” Workshop in Rome

      Agarwal, N., Lewis, L. D., Hirschler, L., Rivera, L. R., Naganawa, S., Levendovszky, S. R., Ringstad, G., Klarica, M., Wardlaw, J., Iadecola, C., Hawkes, C., Carare, R. O., Wells, J., Bakker, E. N. T. P., Kurtcuoglu, V., Bilston, L., Nedergaard, M., Mori, Y., Stoodley, M., Alperin, N. & 2 others, de Leon, M. & van Osch, M. J. P., 2024, In: Journal of Magnetic Resonance Imaging. 59, 2, 19 p.

      Research output: Contribution to journal › Review › Research › peer-review

    3. Published

      Using Fiber Photometry in Mice to Estimate Fluorescent Biosensor Levels During Sleep

      Andersen, Mie, Tsopanidou, Anastasia, Radovanovic, Tessa, Compere, V. N., Hauglund, Natalie Linea, Nedergaard, Maiken & Kjærby, Celia, 2023, In: Bio-protocol. 13, 15, 17 p., e4734.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Not All Lectins Are Equally Suitable for Labeling Rodent Vasculature

      Battistella, R., Kritsilis, M., Matuskova, H., Haswell, D., Cheng, A. X., Meissner, A., Nedergaard, Maiken & Lundgaard, I., 2021, In: International Journal of Molecular Sciences (Online). 22, 21, 11554.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Blood–brain barrier permeable β-blockers linked to lower risk of Alzheimer’s disease in hypertension

      Beaman, Emily Eufaula, Bonde, A. N., Larsen, S. M. U., Ozenne, Brice Maxime Hugues, Lohela, T. J., Nedergaard, Maiken, Gislason, Gunnar Hilmar, Knudsen, Gitte Moos & Holst, S. C., 2023, In: Brain. 146, 3, p. 1141–1151 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Oxygen imaging of hypoxic pockets in the mouse cerebral cortex

      Beinlich, Felix Ralf Michael, Asiminas, Antonios, Untiet, Verena, Bojarowska, Zuzanna, Pla Requena, Virginia Teresa, Sigurdsson, B., Timmel, V., Gehrig, L., Graber, M. H., Hirase, Hajime & Nedergaard, Maiken, 2024, In: Science (New York, N.Y.). 383, 6690, p. 1471-1478 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Human glia can both induce and rescue aspects of disease phenotype in Huntington disease

      Benraiss, A., Wang, S., Herrlinger, S., Li, X., Chandler-Militello, D., Mauceri, J., Burm, H. B., Toner, M., Osipovitch, M., Jim Xu, Q., Ding, F., Wang, F., Kang, N., Kang, J., Curtin, P. C., Brunner, D., Windrem, M. S., Munoz-Sanjuan, I., Nedergaard, Maiken & Goldman, Steven Alan, 7 Jun 2016, In: Nature Communications. 7, 13 p., 11758.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Cerebral small vessel disease: A glymphopathy?

      Benveniste, H. & Nedergaard, Maiken, 2021, In: Current Opinion in Neurobiology. 72, p. 15-21 7 p.

      Research output: Contribution to journal › Review › Research › peer-review

    9. Published

      Glymphatic system

      Benveniste, H. & Nedergaard, Maiken, 2016, Neuroscience in the 21st Century: From Basic to Clinical. 2 ed. Springer, p. 1945-1962 18 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    10. Published

      Glymphatic system dysfunction in neurodegenerative diseases

      Beschorner, Natalie & Nedergaard, Maiken, 2024, In: Current Opinion in Neurology. 37, 2, p. 182-188 7 p.

      Research output: Contribution to journal › Review › Research › peer-review

    11. Published

      The glymphatic system: Current understanding and modeling

      Bohr, T., Hjorth, P. G., Holst, S. C., Hrabětová, S., Kiviniemi, V., Lilius, T., Lundgaard, I., Mardal, K. A., Martens, E. A., Mori, Yuki, Nägerl, U. V., Nicholson, C., Tannenbaum, A., Thomas, J. H., Tithof, J., Benveniste, H., Iliff, J. J., Kelley, D. H. & Nedergaard, Maiken, 2022, In: iScience. 25, 9, 33 p., 104987.

      Research output: Contribution to journal › Review › Research › peer-review

    12. Published

      Inverse correlation of fluctuations of cerebral blood and water concentrations in humans

      Borchardt, V., Korhonen, V., Helakari, H., Nedergaard, Maiken, Myllylä, T. & Kiviniemi, V., 2021, In: European Physical Journal Plus. 136, 5, 497.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Modeling of brain efflux: Constraints of brain surfaces

      Bork, Peter Aleksander Rousing, Hauglund, Natalie Linea, Mori, Yuki, Møllgård, Kjeld, Hjorth, P. G. & Nedergaard, Maiken, 2024, In: Proceedings of the National Academy of Sciences of the United States of America. 121, 16, 12 p., e2318444121.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Astrocyte endfeet may theoretically act as valves to convert pressure oscillations to glymphatic flow

      Bork, Peter Aleksander Rousing, Ladrón-De-Guevara, A., Christensen, A. H., Jensen, K. H., Nedergaard, Maiken & Bohr, T., 2023, In: Journal of the Royal Society Interface. 20, 204, 5 p., 20230050.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Understanding the role of the perivascular space in cerebral small vessel disease

      Brown, R., Benveniste, H., Black, S. E., Charpak, S., Dichgans, M., Joutel, A., Nedergaard, Maiken, Smith, K. J., Zlokovic, B. V. & Wardlaw, J. M., 2018, In: Cardiovascular Research. 114, 11, p. 1462-1473 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Panoptic imaging of transparent mice reveals whole-body neuronal projections and skull-meninges connections

      Cai, R., Pan, C., Ghasemigharagoz, A., Todorov, M. I., Foerstera, B., Zhao, S., Bhatia, H. S., Parra-Damas, A., Mrowka, L., Theodorou, D., Rempfler, M., Xavier, A. L. R., Kress, B. T., Benakis, C., Steinke, H., Liebscher, S., Bechmann, I., Liesz, A., Menze, B., Kerschensteiner, M. & 2 others, Nedergaard, Maiken & Ertuerk, A., 2019, In: Nature Neuroscience. 22, 2, p. 317-327

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Versatile treadmill system for measuring locomotion and neural activity in head-fixed mice

      Carlsen, Eva Maria Meier, Nedergaard, Maiken & Rasmussen, R. N., 2022, In: STAR Protocols. 3, 4, 14 p., 101701.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      SDREAMER: Self-distilled Mixture-of-Modality-Experts Transformer for Automatic Sleep Staging

      Chen, J., Yao, Y., Anderson, M., Hauglund, Natalie Linea, Kjærby, Celia, Untiet, Verena, Nedergaard, Maiken & Luo, J., 2023, p. 131-142. 12 p.

      Research output: Contribution to conference › Paper › Research › peer-review

    19. Published

      Cerebrospinal fluid clearance in Alzheimer disease measured with dynamic PET

      De Leon, M. J., Li, Y., Okamura, N., Tsui, W. H., Saint-Louis, L. A., Glodzik, L., Osorio, R. S., Fortea, J., Butler, T., Pirraglia, E., Fossati, S., Kim, H. J., Carare, R. O., Nedergaard, Maiken, Benveniste, H. & Rusinek, H., 2017, In: Journal of Nuclear Medicine. 58, 9, p. 1471-1476 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Transient but not chronic hyperglycemia accelerates ocular glymphatic transport

      Delle, Christine, Wang, X., Giannetto, M., Newbold, E., Peng, W., Gomolka, Ryszard Stefan, Ladrón-de-Guevara, A., Cankar, Neza, Nielsen, Elise Schiøler, Kjærby, Celia, Weikop, Pia, Mori, Yuki & Nedergaard, Maiken, 2024, In: Fluids and Barriers of the CNS. 21, 1, 13 p., 26.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Long-term high-fat diet increases glymphatic activity in the hypothalamus in mice

      Delle, Christine, Cankar, Neza, Digebjerg Holgersson, C., Hvorup Knudsen, H., Nielsen, Elise Schiøler, Kjærby, Celia, Mori, Yuki, Nedergaard, Maiken & Weikop, Pia, 2023, In: Scientific Reports. 13, 1, 11 p., 4137.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. E-pub ahead of print

      Chronic sleep fragmentation impairs brain interstitial clearance in young wildtype mice

      Deng, Saiyue, Hu, Y., Chen, S., Xue, Yang, Yao, D., Sun, Q., Nedergaard, Maiken, Wang, W. & Ding, Fengfei, 2024, (E-pub ahead of print) In: Journal of Cerebral Blood Flow and Metabolism.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Brain energetics during the sleep-wake cycle

      DiNuzzo, M. & Nedergaard, Maiken, Dec 2017, In: Current Opinion in Neurobiology. 47, p. 65-72 8 p.

      Research output: Contribution to journal › Review › Research › peer-review

    24. Published

      State-Dependent Changes in Brain Glycogen Metabolism

      DiNuzzo, M., Walls, Anne Byriel, Öz, G., Seaquist, E. R., Waagepetersen, Helle S., Bak, Lasse Kristoffer, Nedergaard, Maiken & Schousboe, Arne, 2019, Brain Glycogen Metabolism. DiNuzzo, M. & Schousboe, A. (eds.). Springer, p. 269-309 41 p. (Advances in Neurobiology, Vol. 23).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    25. Published

      Glial cells in schizophrenia: a unified hypothesis

      Dietz, Andrea Grostøl, Goldman, Steven Alan & Nedergaard, Maiken, 2020, In: Lancet Psychiatry. 7, 3, p. 272-281 10 p.

      Research output: Contribution to journal › Review › Research › peer-review

    26. Published

      Local extracellular K+ in cortex regulates norepinephrine levels, network state, and behavioral output

      Dietz, Andrea Grostøl, Weikop, Pia, Hauglund, Natalie Linea, Andersen, Mie, Petersen, Nicolas Caesar, Rose, Laura, Hirase, Hajime & Nedergaard, Maiken, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 40, 9 p., e2305071120.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Changes in the composition of brain interstitial ions control the sleep-wake cycle

      Ding, F., O'Donnell, J., Xu, Q., Kang, N., Goldman, N. & Nedergaard, Maiken, 29 Apr 2016, In: Science. 352, 6285, p. 550-555 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Cerebrospinal fluid is a significant fluid source for anoxic cerebral oedema

      Du, T., Mestre, H., Kress, B. T., Liu, G., Sweeney, A. M., Samson, A. J., Rasmussen, M. K., Mortensen, K. N., Bork, P. A. R., Peng, W., Olveda, G. E., Bashford, L., Toro, E. R., Tithof, J., Kelley, D. H., Thomas, J. H., Hjorth, P. G., Martens, E. A., Mehta, R. I., Hirase, H. & 2 others, Mori, Yuki & Nedergaard, Maiken, 2022, In: Brain. 145, 2, p. 787–797 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      The glymphatic system and Amyotrophic lateral sclerosis

      Eisen, A., Nedergaard, Maiken, Gray, E. & Kiernan, M. C., 2024, In: Progress in Neurobiology. 234, 10 p., 102571.

      Research output: Contribution to journal › Review › Research › peer-review

    30. Published

      Protocol to study molecule exchange between venous blood and CSF in live mice using transcranial bioluminescence imaging

      Esmail, Tina, Nedergaard, Maiken & Beinlich, Felix Ralf Michael, 2023, In: STAR Protocols. 4, 4, 18 p., 102652.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Perivascular pumping of cerebrospinal fluid in the brain with a valve mechanism

      Gan, Y., Holstein-Rønsbo, Stephanie, Nedergaard, Maiken, Boster, K. A. S., Thomas, J. H. & Kelley, D. H., 2023, In: Journal of the Royal Society, Interface. 20, 206, 17 p., 20230288.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Biological sex does not predict glymphatic influx in healthy young, middle aged or old mice

      Giannetto, M., Xia, M., Stæger, Frederik Filip Vinggaard, Metcalfe, T., Vinitsky, H. S., Dang, J. A. M. L., L R Xavier, Anna , Kress, B. T., Nedergaard, Maiken & Hablitz, L. M., 2020, In: Scientific Reports. 10, 1, 8 p., 16073.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Glymphatic fluid transport is suppressed by the aquaporin-4 inhibitor AER-271

      Giannetto, M. J., Gomolka, Ryszard Stefan, Gahn-Martinez, D., Newbold, E. J., Bork, Peter Aleksander Rousing, Chang, E., Gresser, M., Thompson, T., Mori, Yuki & Nedergaard, Maiken, 2024, In: Glia. 72, 5, p. 982-998 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      The Glymphatic System and Pain

      Goldman, N., Hablitz, L. M., Mori, Yuki & Nedergaard, Maiken, 2020, In: Medical Acupuncture. 32, 6, p. 373-376 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Modeling cognition and disease using human glial chimeric mice

      Goldman, Steven Alan, Nedergaard, Maiken & Windrem, M. S., Aug 2015, In: Glia. 63, 8, p. 1483-1493 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      CSF space volumetry using 3D-CISS in Aqp4-deficient mice – quantitative analysis and technical advances

      Gomolka, Ryszard Stefan, Nedergaard, Maiken & Mori, Yuki, 2021, Book of Abstracts ESMRMB 2021 Online 38th Annual Scientific Meeting 7-9 October 2021. Springer, Vol. 34. p. S95-6 2 p. (Magnetic Resonance Materials in Physics, Biology, and Medicine; No. 34).

      Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

    37. Published

      Loss of aquaporin-4 results in glymphatic system dysfunction via brain-wide interstitial fluid stagnation

      Gomolka, Ryszard Stefan, Hablitz, L. M., Mestre, H., Giannetto, M., Du, Ting, Hauglund, Natalie Linea, Xie, L., Peng, W., Martinez, P. M., Nedergaard, Maiken & Mori, Yuki, 2023, In: eLife. 12, 36 p., e82232.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Cellular Control of Brain Capillary Blood Flow: In Vivo Imaging Veritas

      Grutzendler, J. & Nedergaard, Maiken, 2019, In: Trends in Neurosciences. 42, 8, p. 528-536 9 p.

      Research output: Contribution to journal › Review › Research › peer-review

    39. Published

      Increased glymphatic influx is correlated with high EEG delta power and low heart rate in mice under anesthesia

      Hablitz, L. M., Vinitsky, H. S., Sun, Q., Stæger, Frederik Filip Vinggaard, Sigurdsson, B., Mortensen, K. N., Lilius, T. O. & Nedergaard, Maiken, 2019, In: Science Advances. 5, 2, 9 p., eaav5447.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      The glymphatic system: A novel component of fundamental neurobiology

      Hablitz, L. M. & Nedergaard, Maiken, 2021, In: Journal of Neuroscience. 41, 37, p. 7698-7711 14 p.

      Research output: Contribution to journal › Review › Research › peer-review

    41. Published

      Circadian control of brain glymphatic and lymphatic fluid flow

      Hablitz, L. M., Plá, V., Giannetto, M., Vinitsky, H. S., Stæger, Frederik Filip Vinggaard, Metcalfe, T., Nguyen, R., Benrais, A. & Nedergaard, Maiken, 2020, In: Nature Communications. 11, 1, 4411.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Meningeal Lymphangiogenesis and Enhanced Glymphatic Activity in Mice with Chronically Implanted EEG Electrodes

      Hauglund, Natalie Linea, Kusk, P., Kornum, Birgitte Rahbek & Nedergaard, Maiken, 2020, In: Journal of Neuroscience. 40, 11, p. 2371-2380 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Cleaning the sleeping brain – the potential restorative function of the glymphatic system

      Hauglund, Natalie Linea, Pavan, C. & Nedergaard, Maiken, 1 Jun 2020, In: Current Opinion in Physiology. 15, 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Effect of sleep deprivation and NREM sleep stage on physiological brain pulsations

      Helakari, H., Järvelä, M., Väyrynen, T., Tuunanen, J., Piispala, J., Kallio, M., Ebrahimi, S. M., Poltojainen, V., Kananen, J., Elabasy, A., Huotari, N., Raitamaa, L., Tuovinen, T., Korhonen, V., Nedergaard, Maiken & Kiviniemi, V., 2023, In: Frontiers in Neuroscience. 17, 1275184.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Human NREM Sleep Promotes Brain-Wide Vasomotor and Respiratory Pulsations

      Helakari, H., Korhonen, V., Holst, S. C., Piispala, J., Kallio, M., Väyrynen, T., Huotari, N., Raitamaa, L., Tuunanen, J., Kananen, J., Järvelä, M., Tuovinen, T., Raatikainen, V., Borchardt, V., Kinnunen, H., Nedergaard, Maiken & Kiviniemi, V., 2022, In: Journal of Neuroscience. 42, 12, p. 2503-2515 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Locomotion Induces Fundamentally Different Patterns of Ca2+Signaling in Astrocytes and Neurons

      Hirase, Hajime & Nedergaard, Maiken, 2023, In: Function. 4, 4, 2 p., zqad028.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    47. Published

      Glymphatic influx and clearance are accelerated by neurovascular coupling: [Inkl. Correction]

      Holstein-Rønsbo, Stephanie, Gan, Y., Giannetto, M. J., Rasmussen, Martin Kaag, Sigurdsson, B., Beinlich, Felix Ralf Michael, Rose, Laura, Untiet, Verena, Hablitz, L. M., Kelley, D. H. & Nedergaard, Maiken, 2023, In: Nature Neuroscience. 26, p. 1042–1053

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Air pollution, glymphatic impairment, and Alzheimer's disease

      Hussain, R., Graham, U., Elder, A. & Nedergaard, Maiken, 2023, In: Trends in Neurosciences. 46, 11, p. 901-911 11 p.

      Research output: Contribution to journal › Review › Research › peer-review

    49. Published

      Managing noradrenaline after traumatic brain injury

      Hussain, R. & Nedergaard, Maiken, 2024, In: Clinical and Translational Medicine. 14, 1, 3 p., e1562.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    50. Published

      Potentiating glymphatic drainage minimizes post-traumatic cerebral oedema

      Hussain, R., Tithof, J., Wang, W., Cheetham-West, A., Song, W., Peng, W., Sigurdsson, B., Kim, D., Sun, Q., Peng, S., Pla Requena, Virginia Teresa, Kelley, D. H., Hirase, Hajime, Castorena-Gonzalez, J. A., Weikop, Pia, Goldman, Steven Alan, Davis, M. J. & Nedergaard, Maiken, 2023, In: Nature. 623, p. 992–1000 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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