Leila Lo Leggio
Professor
Department of Chemistry
Universitetsparken 5
2100 København Ø
- 2024
- Published
A frontier-orbital view of the initial steps of lytic polysaccharide monooxygenase reactions
Wieduwilt, E. K., Lo Leggio, Leila & Hedegård, E. D., 2024, In: Dalton Transactions (Online). 53, 13, p. 5796-5807 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CI:Mor interactions in the lysogeny switches of Lactococcus lactis TP901-1 and Staphylococcus aureus φ13 bacteriophages
Varming, A. K., Huang, Zhiyu, Hamad, G. M., Rasmussen, K. K., Ingmer, Hanne, Kilstrup, M. & Lo Leggio, Leila, 2024, In: Microbiome Research Reports. 3, 2, 16 p., 15.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chemoenzymatic indican for light-driven denim dyeing
Bidart, G. N., Teze, D., Jansen, C. U., Pasutto, E., Putkaradze, N., Sesay, A. M., Fredslund, F., Lo Leggio, Leila, Ögmundarson, O., Sukumara, S., Qvortrup, K. & Welner, D. H., 2024, In: Nature Communications. 15, 1, 11 p., 1489.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polysaccharide utilization loci from Bacteroidota encode CE15 enzymes with possible roles in cleaving pectin-lignin bonds
Seveso, A., Mazurkewich, S., Banerjee, S., Poulsen, Jens-Christian Navarro, Lo Leggio, Leila & Larsbrink, J., 2024, In: Applied and Environmental Microbiology. 90, 1, 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
AA16 Oxidoreductases Boost Cellulose-Active AA9 Lytic Polysaccharide Monooxygenases from Myceliophthora thermophila
Sun, P., Huang, Zhiyu, Banerjee, S., Kadowaki, M. A. S., Veersma, R. J., Magri, S., Hilgers, R., Muderspach, Sebastian Jannick, Laurent, C. V. F. P., Ludwig, R., Cannella, D., Lo Leggio, Leila, van Berkel, W. J. H. & Kabel, M. A., 2023, In: ACS Catalysis. 13, 7, p. 4454-4467 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucuronoyl esterases – enzymes to decouple lignin and carbohydrates and enable better utilization of renewable plant biomass
Larsbrink, J. & Lo Leggio, Leila, 2023, In: Essays in Biochemistry. 67, 3, p. 493-503 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Joint X-ray/neutron structure of Lentinus similis AA9_A at room temperature
Tandrup, T., Lo Leggio, Leila & Meilleur, F., 2023, In: Acta crystallographica. Section F, Structural biology communications. 79, 1, p. 1-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural and functional investigation of a fungal member of carbohydrate esterase family 15 with potential specificity for rare xylans
Mazurkewich, S., Scholzen, K. C., Brusch, R. H., Poulsen, Jens-Christian Navarro, Theibich, Yusuf, Hüttner, S., Olsson, L., Larsbrink, J. & Lo Leggio, Leila, 2023, In: Acta crystallographica. Section D, Structural biology. 79, 6, p. 545-555 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure, function, and protein engineering of GH53 β-1,4-galactanases
Muderspach, Sebastian Jannick, Jensen, K., Krogh, K. B. R. M. & Lo Leggio, Leila, 2023, Glycoside Hydrolases: Biochemistry, Biophysics, and Biotechnology. Elsevier, p. 295-322 28 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 2022
- Published
Mechanism and biomass association of glucuronoyl esterase: an α/β hydrolase with potential in biomass conversion
Zong, Z., Mazurkewich, S., Pereira, C. S., Fu, H., Cai, W., Shao, X., Skaf, M. S., Larsbrink, J. & Lo Leggio, Leila, Dec 2022, In: Nature Communications. 13, 1, 10 p., 1449.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in active-site geometry on X-ray photo-reduction of a lytic polysaccharide monooxygenase active-site copper and saccharide binding
Tandrup, T., Muderspach, Sebastian Jannick, Banerjee, S., Santoni, G., Ipsen, J. O., Hernandez Rollan, Cristina, Norholm, M. H. H., Johansen, Katja Salomon, Meilleur, F. & Lo Leggio, Leila, Sep 2022, In: IUCrJ. 9, 5, p. 666-681 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Flexible linker modulates the binding affinity of the TP901-1 CI phage repressor to DNA
Varming, A. K., Rasmussen, K. K., Zong, Z., Thulstrup, Peter Waaben, Kilstrup, M. & Lo Leggio, Leila, 2022, In: FEBS Journal. 289, 4, p. 1135-1148 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protonation State of an Important Histidine from High Resolution Structures of Lytic Polysaccharide Monooxygenases
Banerjee, S., Muderspach, Sebastian Jannick, Tandrup, T., Frandsen, Kristian Erik Høpfner, Singh, R. K., Ipsen, J. O., Hernandez Rollan, Cristina, Nørholm, M. H. H., Bjerrum, Morten Jannik, Johansen, Katja Salomon & Lo Leggio, Leila, 2022, In: Biomolecules. 12, 2, 15 p., 194.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Engineering the substrate binding site of the hyperthermostable archaeal endo-β-1,4-galactanase from Ignisphaera aggregans
Muderspach, Sebastian Jannick, Fredslund, F., Volf, V., Poulsen, Jens-Christian Navarro, Blicher, T. H., Clausen, M. H., Rasmussen, K. K., Krogh, K. B. R. M., Jensen, K. & Lo Leggio, Leila, 1 Dec 2021, In: Biotechnology for Biofuels. 14, 1, 16 p., 183.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of the genetic switch from phage ɸ13 important for Staphylococcus aureus colonization in humans
Kristensen, C. S., Varming, A. K., Leinweber, H. A. K., Hammer, K., Lo Leggio, Leila, Ingmer, Hanne & Kilstrup, M., 1 Oct 2021, In: MicrobiologyOpen. 10, 5, 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural and Functional Analysis of a Multimodular Hyperthermostable Xylanase-Glucuronoyl Esterase from Caldicellulosiruptor kristjansonii
Krska, D., Mazurkewich, S., Brown, H. A., Theibich, Yusuf, Poulsen, Jens-Christian Navarro, Morris, A. L., Koropatkin, N. M., Lo Leggio, Leila & Larsbrink, J., 13 Jul 2021, In: Biochemistry. 60, 27, p. 2206-2220 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Crystal structures of Val58Ile tryptophan repressor in a domain-swapped array in the presence and absence of L-tryptophan
Sprenger, J., Lawson, C. L., Von Wachenfeldt, C., Lo Leggio, Leila & Carey, J., 1 Jul 2021, In: Acta Crystallographica Section F: Structural Biology Communications. 77, 7, p. 215-225 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probing the determinants of the transglycosylation/hydrolysis partition in a retaining α-L-arabinofuranosidase
Zhao, J., Tandrup, T., Bissaro, B., Barbe, S., Poulsen, Jens-Christian Navarro, André, I., Dumon, C., Lo Leggio, Leila, O'Donohue, M. J. & Fauré, R., 25 May 2021, In: New Biotechnology. 62, p. 68-78 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimating the accuracy of calculated electronparamagnetic resonance hyperfine couplings for alytic polysaccharide monooxygenase
Theibich, Y. A., Sauer, Stephan P. A., Lo Leggio, Leila & Hedegård, E. D., 12 Jan 2021, In: Computational and Structural Biotechnology Journal. 19, p. 555-567 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of the molecular determinants driving the substrate specificity of fungal lytic polysaccharide monooxygenases (LPMOs)
Frandsen, Kristian Erik Høpfner, Haon, M., Grisel, S., Henrissat, B., Lo Leggio, Leila & Berrin, J., 1 Jan 2021, In: Journal of Biological Chemistry. 296, 11 p., 100086.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Calmodulin complexes with brain and muscle creatine kinase peptides
Sprenger, J., Trifan, A., Patel, N., Vanderbeck, A., Bredfelt, J., Tajkhorshid, E., Rowlett, R., Lo Leggio, Leila, Åkerfeldt, K. S. & Linse, S., 2021, In: Current Research in Structural Biology. 3, p. 121-132 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Controlling the fractal dimension in self-assembly of terpyridine modified insulin by Fe2+ and Eu3+ to direct in vivo effects
Mishra, N. K., Østergaard, M., Midtgaard, S. R., Strindberg, S. S., Winkler, S., Wu, S., Sørensen, Thomas Just, Hassenkam, Tue, Poulsen, Jens-Christian Navarro, Lo Leggio, Leila, Nielsen, Hanne Mørck, Arleth, Lise, Christensen, Niels Johan, Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2021, In: Nanoscale. 13, 18, p. 8467–8473 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Copper binding and reactivity at the histidine brace motif: insights from mutational analysis of the Pseudomonas fluorescens copper chaperone CopC
Ipsen, J. Ø., Hernández‐Rollán, C., Muderspach, Sebastian Jannick, Brander, Søren, Bertelsen, A. B., Jensen, Poul Erik, Nørholm, M. H. H., Lo Leggio, Leila, Johansen, Katja Salomon & Ferguson, S. (ed.), 2021, In: FEBS Letters. 595, 12, p. 1708-1720 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Guest-protein incorporation into solvent channels of a protein host crystal (hostal)
Sprenger, J., Carey, J., Schulz, Alexander, Drouard, F., Lawson, C. L., Von Wachenfeldt, C., Linse, S. & Lo Leggio, Leila, 2021, In: Acta crystallographica Section D: Structural biology . 77, p. 471-485 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of lytic polysaccharide monooxygenase by natural plant extracts
Tokin, Radina, Frandsen, Kristian Erik Høpfner, Ipsen, J. Ø., Lo Leggio, Leila, Poojary, Mahesha Manjunatha, Berrin, J., Grisel, S., Brander, Søren, Jensen, Poul Erik & Johansen, Katja Salomon, 2021, In: New Phytologist. 232, 3, p. 1337–1349 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 13810
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2031
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Purification, crystal structure determination and functional characterization of type III antifreeze proteins from the European eelpout Zoarces viviparus
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
1598
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A structural overview of GH61proteins – fungal cellulose degrading polysaccharide monooxygenases
Research output: Contribution to journal › Journal article › Research › peer-review
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500
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Learning from oligosaccharide soaks of crystals of an AA13 lytic polysaccharide monooxygenase: crystal packing, ligand binding and active-site disorder
Research output: Contribution to journal › Journal article › Research › peer-review
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