Kirsten Grønbæk

Blood sampling patterns in primary care change several years before a cancer diagnosis

Christensen, M. E., Grand, Mia Klinten, Kriegbaum, Margit, Lind, B. S., Grønbæk, Kirsten, Persson, F., Johansen, Christoffer & Andersen, C. L., 2024, In: Acta oncologica (Stockholm, Sweden). 63, p. 17-22 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Cardiovascular diseases after high-dose chemotherapy and autologous stem cell transplant for lymphoma: A Danish population-based study

Baech, J., Husby, S., Trab, Trine, Kragholm, K., Brown, Peter de Nully, Gørløv, J. S., Jørgensen, J. M., Gudbrandsdottir, S., Severinsen, M. T., Grønbæk, Kirsten, Larsen, T. S., Wästerlid, T., Eloranta, S., Smeland, K. B., Jakobsen, L. H. & El-Galaly, T. C., 2024, In: British Journal of Haematology. 204, 3, p. 967-975

Research output: Contribution to journal › Journal article › Research › peer-review

Clonal hematopoiesis and COVID-19 hospitalization in Danish adults

Burgos Sequeros, C., Tulstrup, M., Bliddal, S., Sørensen, K. M., Nissen, I., Rezahosseini, O., Brooks, P. T., Feenstra, B., Gang, A. O., Geller, F., Hald, A., Harboe, Z. B., Helleberg, M., Jespersen, J. S., Lebech, A. M., Lindegaard, B., Mogensen, T. H., Møller, M. E. E., Nielsen, C. H., Niemann, C. U. & 13 others, Podlekareva, D., Sejdic, A., Sørensen, E., Teglgaard, R. S., Tommerup, Niels, Weis, Nina, Brunak, Søren, Pedersen, Ole Birger Vesterager, Banasik, Karina, Feldt-Rasmussen, Ulla, Nielsen, Susanne Dam, Ostrowski, Sisse Rye & Grønbæk, Kirsten, 2024, In: HemaSphere. 8, 3, 5 p., e58.

Research output: Contribution to journal › Letter › Research › peer-review

Clonal hematopoiesis of indeterminate potential in persons with HIV

Knudsen, A. D., Eskelund, C. W., Benfield, Thomas, Zhao, Y., Gelpi, M., Køber, Lars Valeur, Trøseid, M., Kofoed, Klaus Fuglsang, Ostrowski, Sisse Rye, Reilly, C., Borges, Á. H., Grønbæk, Kirsten & Nielsen, S. D., 2024, In: AIDS. 38, 4, p. 487-495 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Expanding the understanding of telomere biology disorder with reports from two families harboring variants in ZCCHC8 and TERC

Nitschke, N. J., Jelsig, A. M., Lautrup, C., Lundsgaard, M., Severinsen, M. T., Cowland, J. B., Maroun, L. L., Andersen, M. K. & Grønbæk, Kirsten, 2024, (E-pub ahead of print) In: Clinical Genetics.

Research output: Contribution to journal › Journal article › Research › peer-review

Family caregiver quality of life and symptom burden in patients with hematological cancer: A Danish nationwide cross-sectional study

Nielsen, I. H., Tolver, Anders, Piil, K., Kjeldsen, L., Grønbæk, Kirsten & Jarden, Mary Ellen, 2024, In: European Journal of Oncology Nursing. 69, 9 p., 102538.

Research output: Contribution to journal › Journal article › Research › peer-review

Humoral Immune Responses after an Omicron-Adapted Booster BNT162b2 Vaccination in Patients with Lymphoid Malignancies

Heftdal, Line Dam, Hansen, Cecilie Bo, Hamm, S. R., Pérez-Alós, L., Fogh, K., Pries-Heje, M., Hasselbalch, R. B., Møller, D. L., Gang, Anne Ortved, Ostrowski, Sisse Rye, Frikke-Schmidt, Ruth, Sørensen, E., Hilsted, Linda, Bundgård, Henning, Garred, Peter, Iversen, Kasper, Sabin, C., Nielsen, Susanne Dam & Grønbæk, Kirsten, 2024, In: Viruses. 16, 1, 15 p., 11.

Research output: Contribution to journal › Journal article › Research › peer-review

Low mortality from COVID-19 infection in patients with B-cell lymphoma after bispecific CD20xCD3 therapy

Kyvsgaard, Emil Ramsø, Riley, C., Clausen, M. R., Harsløf, Mads, Heftdal, Line Dam, Niemann, Carsten, Grønbæk, Kirsten, Hutchings, M. & Husby, Simon, 2024, In: British Journal of Haematology. 204, 1, p. 356-360 5 p.

Research output: Contribution to journal › Letter › Research › peer-review

MYC protein is a high-risk factor in mantle cell lymphoma and identifies cases beyond morphology, proliferation and TP53/p53 - a Nordic Lymphoma Group study

Rodrigues, J. M., Hollander, P., Schmidt, L., Gkika, E., Razmara, M., Kumar, D., Geisler, C., Grønbæk, Kirsten, Eskelund, C. W., Räty, R., Kolstad, A., Sundström, C., Glimelius, I., Porwit, A., Jerkeman, M. & Ek, S., 2024, In: Haematologica. 109, 4, p. 1171-1183 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Precision hematology: Navigating the evolution of diagnostic classifications in the era of globalized medicine

Macintyre, E., Döhner, K., Grønbæk, Kirsten, Dreyling, M., Huntly, B., Almeida, A. & Gribben, J., 2024, In: HemaSphere. 8, 4, 3 p., e65.

Research output: Contribution to journal › Editorial › Research › peer-review

Risk of cancer in relatives of patients with myelodysplastic neoplasia and acute leukemias

Nitschke, N. J., Rostgaard, K., Andersen, M. K., Hjalgrim, Henrik & Grønbæk, Kirsten, 2024, In: Cancer Epidemiology. 88, 6 p., 102523.

Research output: Contribution to journal › Journal article › Research › peer-review

CD3xCD20 Bispecific Antibodies Yields Long-Term Survival in Relapsed/Refractory B Cell Lymphoma: A Follow-up Study of Patients Treated in Pivotal Phase 1/2 Trials

Kyvsgaard, Emil Ramsø, Clausen, M. R., Hasselbalch Riley, A. C., Niemann, Carsten, Grønbæk, Kirsten, Hutchings, M. & Husby, Simon, 28 Nov 2023, In: Blood. 142, Supplement 1, p. 618-618

Research output: Contribution to journal › Journal article › Research › peer-review

Endogenous Retroviral Elements Constitute a Promising Vaccine Antigen Source for Haematological Malignancies

Thygesen, Christian Bahne, Klausen, M. S., Thuesen, N., Garde, C., Jespersen, A., Grønbæk, Kirsten, Kringelum, J. & Bundgård Sørensen, A. B., 28 Nov 2023, In: Blood. 142, Supplement 1, p. 243-243

Research output: Contribution to journal › Journal article › Research › peer-review

Immunohistochemical Tumor Expression Predicts Response to CD3xCD20 Bispecific Antibodies in Patients with Relapsed/Refractory B Cell Lymphoma

Kyvsgaard, Emil Ramsø, Clausen, M. R., Hasselbalch Riley, A. C., Niemann, Carsten, Sjö, Lene Dissing, Grønbæk, Kirsten, Hutchings, M. & Husby, Simon, 28 Nov 2023, In: Blood. 142, Supplement 1, p. 6113-6113

Research output: Contribution to journal › Journal article › Research › peer-review

Overall Survival in Patients with Ccus Depends on Presence of Anemia

Træden, D., Tulstrup, Morten Rytter, Johansen, Morten Munk, mxz703, mxz703, Marcher, C., Raaschou-jensen, K., Stidsholt Roug, A., Severinsen, M. T., Porse, Bo Torben, Theilgaard-Mønch, Kim, Jespersen, J., Cowland, J. B., Sjö, Lene Dissing, Andersen, M. K., Grønbæk, Kirsten & Hansen, Jakob Werner, 28 Nov 2023, In: Blood. 142, Supplement 1, p. 1864-1864

Research output: Contribution to journal › Journal article › Research › peer-review

10-year nationwide trends in incidence, treatment patterns, and mortality of patients with myelodysplastic syndromes in Denmark

Lauritsen, T. B., Nørgaard, J. M., Dalton, Susanne Oksbjerg, Grønbæk, Kirsten, El-Galaly, T. C. & Østgård, L. S. G., 2023, In: Leukemia Research. 128, 10 p., 107056.

Research output: Contribution to journal › Journal article › Research › peer-review

A Lack of Diversity, Equity, and Inclusion in Clinical Research Has Direct Impact on Patient Care

El-Galaly, T. C., Gaidzik, V. I., Gaman, M. A., Antic, D., Okosun, J., Copland, M., Sexl, V., Fielding, A. K., Doeswijk, R., Parker, H., Dreyling, M., Döhner, K., Almeida, A. M., Macintyre, E., Gribben, J. G. & Grønbæk, Kirsten, 2023, In: HemaSphere. 7, 3, 4 p., e842.

Research output: Contribution to journal › Editorial › Research

A second update on mapping the human genetic architecture of COVID-19

Kanai, M., Andrews, S., Cordioli, M., Stevens, C., Neale, B. M., Daly, M., Ganna, A., Pathak, G. A., Ellinghaus, D., Banasik, K., Brunak, S., Pedersen, O. B., Westergaard, D., Sequeros, C. B., Nissen, J., Feldt-Rasmussen, U., Grønbæk, K., Ostrowski, S. R., Guindo-Martinez, M., Garcia, S. M. & 70 others, Hjalgrim, Henrik, Admin team lead, A. T. L., Admin team member, A. T. M., Analysis team lead, A. T. L., Analysis team member, A. T. M., Data collection lead, D. C. L., Data collection member, D. C. M., Manuscript analysis team lead, M. A. T. L., Manuscript analysis team members: Mendelian randomization, M. A. T. M. M. R., Manuscript analysis team members: methods development, M. A. T. M. M. D., Manuscript analysis team members: phenome-wide association study, M. A. T. M. P. A. S., Manuscript analysis team members: principal component projection, gene prioritization, M. A. T. M. P. C. P. G. P., Project management lead, P. M. L., Scientific communication lead, S. C. L., Scientific communication member, S. C. M., Writing group lead, W. G. L., Writing group member, W. G. M., 23andMe, 2., Adolescent brain and cognitive development study, A. B. A. C. D. S., Analysis group, A. G., Armenia_Covid-19hg, A., Assessment of the influence of clinical, functional, immunological and genetic factors on the severity of the course of coronavirus infection with SARS-CoV-2 and post-COVID syndrome, A. O. T. I. O. C. F. I. A. G. F. O. T. S. O. T. C. O. C. I. W. S. A. P. S., Avon Longitudinal Study of Parents and Children (ALSPAC), A. L. S. O. P. A. C. (., BelCovid, B., Biobanque Quebec COVID19, B. Q. C., BioVU, B., Bonn Study of COVID-19 Genetics, B. S. O. C. G., CGEn HostSeq—Canadian COVID-19 Human Host Genome Sequencing Databank, C. H. C. H. H. G. S. D., Colorado Center for Personalized Medicine—CCPM, C. C. F. P. M., COMRI/Virology Study, C. S., Covid19 Ioannina Biobank, C. I. B., COVID19-Host(a)ge, C., Covid19hg-CL, C., Danish COVID-19 Genomic Consortium, D. C. G. C., Egypt hgCOVID hub, E. H. H., EraCORE, E., FinnGen, F., French hgCOVID, F. H., GCAT. Genomes For Life, G. G. F. L., Genes & Health, G. &. H., Genetic influences on severity of COVID-19 illness in Korea, G. I. O. S. O. C. I. I. K., GenOMICC, G., Genotek COVID-19 study, G. C. S., Helix Exome+ COVID-19 Phenotypes, H. E. C. P., Host Genetic Factors for COVID-19 Severity and Outcome in Western Indian Population, H. G. F. F. C. S. A. O. I. W. I. P., Host Genetics in COVID Cohorts of Mixed ancestry from Mexico, H. G. I. C. C. O. M. A. F. M., Japan Coronavirus Taskforce, J. C. T., Japan NCGM-COVID19, J. N., Jordan COVID-19 Host Genomics Initiative (JCHGI), J. C. H. G. I. (., Leadership, L., Lung eQTL Consortium, L. E. C., Mass General Brigham—Host Vulnerability to COVID-19, M. G. B. V. T. C., MexGen-COVID, M., Pa-COVID-19, P., Project management group, P. M. G., Project management support, P. M. S., Qatar Genome Program, Q. G. P., SARS-CoV-2 and Host Genome sequencing, S. A. H. G. S., Scientific communication group, S. C. G., Search for Genomic Markers Predicting the Severity of the response to COVID-19, S. F. G. M. P. T. S. O. T. R. T. C., Spanish COalition to Unlock Research on host GEnetics on COVID-19 (SCOURGE), S. C. T. U. R. O. H. G. O. C. (., The Danish Blood Donor Study, T. D. B. D. S., The Genetic Predisposition to severe COVID-19, T. G. P. T. S. C., Tirschenreuth Study (TiKoco), T. S. (., UCLA Precision Health COVID-19 Host Genomics Biobank, U. P. H. C. H. G. B., UK Biobank, U. B., Variability in Immune Response Genes and Severity of SARS-CoV-2 Infection (INMUNGEN-CoV2 study), V. I. I. R. G. A. S. O. S. I. (. S., Website development, W. D., Writing Group, W. G. & The COVID-19 Host Genetics Initiative, T. C. H. G. I., 2023, In: Nature. 621, 7977, p. E7-E26 23 p.

Research output: Contribution to journal › Comment/debate › Research › peer-review

Concurrent Inhibition of Akt and ERK Using TIC-10 Can Overcome Venetoclax Resistance in Mantle Cell Lymphoma

Granau, Agnete Marie, Andersen, P. A., Jakobsen, T., Taouxi, K., Dalila, N., Mogensen, J. B., Kristensen, L. S., Grønbæk, Kirsten & Dimopoulos, K., 2023, In: Cancers. 15, 2, 15 p., 510.

Research output: Contribution to journal › Journal article › Research › peer-review

Exploring new prognostic biomarkers in Mantle Cell Lymphoma: a comparison of the circSCORE and the MCL35 score

Salim, Ruth, Husby, Simon, Winther Eskelund, C., Scott, D. W., Holte, H., Kolstad, A., Räty, R., Ek, S., Jerkeman, M., Geisler, C., Sommer Kristensen, L., Dahl, M. & Grønbæk, Kirsten, 2023, In: Leukemia and Lymphoma. 64, 8, p. 1414-1423

Research output: Contribution to journal › Journal article › Research › peer-review

Frequency and Functional Characterization of RUNX1 Germline Variants in Myeloid Neoplasms

Nitschke, N. J., Almosailleakh, M., Niu, Yiyuan, Hansen, Jakob Werner, Raaschou-Jensen, K., Jespersen, Jakob Schmidt, Severinsen, M. T., Roug, A. S., Frödin, Morten, Weischenfeldt, Joachim Lütken, Andersen, M. K. & Grønbæk, Kirsten, 2023, In: Human Mutation. 2023, 11 p., 4738660.

Research output: Contribution to journal › Journal article › Research › peer-review

Germline Variant in ZCCHC8 Is Associated with Pulmonary Fibrosis, Bone Marrow Failure, Liver Inflammation, Early Grey Hair and Short Telomer Length

Nitschke, N. J., Jelsig, A. M., Andersen, M. K. & Grønbæk, Kirsten, 2023, In: Blood. 142, Supplement 1, p. 5668 1 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Humoral and cellular immune responses after three or four doses of BNT162b2 in patients with hematological malignancies

Heftdal, L. D., Hamm, S. R., Pérez-Alós, L., Madsen, J. R., Armenteros, J. J. A., Fogh, K., Kronborg, C. C., Vallentin, A. P., Hasselbalch, R. B., Møller, D. L., Hansen, C. B., Pries-Heje, M., Gang, A. O., Ostrowski, S. R., Frikke-Schmidt, R., Sørensen, E., Hilsted, L., Bundgaard, H., Iversen, K., Garred, P. & 2 others, Nielsen, S. D. & Grønbæk, Kirsten, 2023, In: European Journal of Haematology. 111, 2, p. 229-239 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Humoral and cellular immune responses eleven months after the third dose of BNT162b2 an mRNA-based COVID-19 vaccine in people with HIV – a prospective observational cohort study

Heftdal, Line Dam, Pérez-Alós, L., Hasselbalch, R. B., Hansen, Cecilie Bo, Hamm, S. R., Møller, D. L., Pries-Heje, M., Fogh, K., Gerstoft, Jan, Grønbæk, Kirsten, Ostrowski, Sisse Rye, Frikke-Schmidt, Ruth, Sørensen, E., Hilsted, L., Bundgård, Henning, Garred, Peter, Iversen, Kasper, Sabin, C. & Nielsen, S. D., 2023, In: EBioMedicine. 93, 9 p., 104661.

Research output: Contribution to journal › Journal article › Research › peer-review

Impact of U2AF1 mutations on circular RNA expression in myelodysplastic neoplasms

Wedge, E., Ahmadov, U., Hansen, T. B., Gao, Z., Tulstrup, Morten Rytter, Côme, Christophe Roger Michel, Nonavinkere Srivatsan, S., Ahmed, T., Jespersen, Jakob Schmidt, Schlotmann, Balthasar Clemens, Schöllkopf, C., Raaschou-Jensen, K., Ødum, Niels, Kjems, J., Bak, R. O., Walter, M. J., Grønbæk, Kirsten & Kristensen, L. S., 2023, In: Leukemia. 37, p. 1113-1125

Research output: Contribution to journal › Journal article › Research › peer-review

LEP promoter methylation in the initiation and progression of clonal cytopenia of undetermined significance and myelodysplastic syndrome

Kaastrup, K., Gillberg, Linn, Mikkelsen, Stine Ulrik, mxz703, mxz703, Schöllkopf, C., Mortensen, B. K., Porse, Bo Torben, Hansen, Jakob Werner & Grønbæk, Kirsten, 2023, In: Clinical Epigenetics. 15, 13 p., 91.

Research output: Contribution to journal › Journal article › Research › peer-review

Lenalidomide Maintenance in Multiple Myeloma: A Retrospective, Nationwide, Real-World Study

Harsløf, Mads, Chanchiri, I., Silkjær, T., Frølund, U. C., Teodorescu, E. M., Nielsen, K. B., Nielsen, P. I., Pedersen, P. T., Iversen, K. F., Grønbæk, Kirsten, Vangsted, Annette Juul, Thorsteinsdottir, S. & Szabo, A. G., 2023, In: Blood. 142, Supplement 1, p. 1979 1 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Loss of the KN Motif and AnKyrin Repeat Domain 1 (KANK1) Leads to Lymphoid Compartment Dysregulation in Murine Model

Almosailleakh, M., Bentivegna, Sofia, Narcisi, S., Benquet, Sébastien Jean, Gillberg, Linn, Montaño-Almendras, C. P., Savickas, S., Schoof, E. M., Wegener, A., Luche, H., Jensen, Henrik Elvang, Côme, Christophe Roger Michel & Grønbæk, Kirsten, 2023, In: Genes. 14, 10, 1947.

Research output: Contribution to journal › Journal article › Research › peer-review

Monocytosis in primary care and risk of haematological malignancies

Christensen, M. E., Siersma, Volkert Dirk, Kriegbaum, Margit, Lind, B. S., Samuelsson, J., Østgård, L. S. G., Grønbæk, Kirsten & Andersen, Christen Bertel L, 2023, In: European Journal of Haematology. 110, 4, p. 362-370 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Overexpression of the key metabolic protein CPT1A defines mantle cell lymphoma patients with poor response to standard high-dose chemotherapy independent of MIPI and complement established high-risk factors

Gerdtsson, A. S., de Matos Rodrigues, J., Eskelund, C. W., Husby, Simon, Grønbæk, Kirsten, Räty, R., Kolstad, A., Geisler, C., Porwit, A., Jerkeman, M. & Ek, S., 2023, In: Haematologica. 108, 4, p. 1092-1104 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

ProGraME: A novel flow cytometry algorithm for the diagnosis of low-risk myelodysplastic syndromes in patients with cytopenia

Therkelsen, J., Træden, D. W., Schjødt, I., Andersen, M. K., Sjö, Lene Dissing, Hansen, Jakob Werner, Grønbæk, Kirsten & Dimopoulos, K., 2023, In: European Journal of Haematology. 111, 6, 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Second primary malignancies in patients with lymphoma in Denmark after high-dose chemotherapy and autologous haematopoietic stem-cell transplantation: a population-based, retrospective cohort study

Trab, Trine, Baech, J., Jakobsen, L. H., Husby, S., Severinsen, M. T., Eloranta, S., Gørløv, J. S., Jørgensen, J. M., Gudbrandsdottir, S., Larsen, T. S., Brown, Peter de Nully, Grønbæk, Kirsten, Smedby, K. E. & El-Galaly, T. C., 2023, In: The Lancet Haematology. 10, 10, p. e838-e848 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes

Trempenau, M. L., Schuster, Mikkel Bruhn, Pundhir, Sachin, Araújo Pereira, Mafalda, Kalvisa, A., Tapia, Marta Cecylia, Su, Jinyu, Ge, Y., de Boer, Bauke, Balhuizen, Alexander, Bagger, F. O., Shliaha, P., Sroczynska, P., Walfridsson, J., Grønbæk, Kirsten, Theilgaard-Mønch, Kim, Jensen, O. N., Helin, K. & Porse, Bo Torben, 2023, In: Leukemia. 37, 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

"Randomized phase II study of azacitidine ± lenalidomide in higher-risk myelodysplastic syndromes and acute myeloid leukemia with a karyotype including Del(5q)"

Rasmussen, B., Gohring, G., Bernard, E., Nilsson, L., Tobiasson, M., Jadersten, M., Garelius, H., Dybedal, I., Gronbaek, K., Ejerblad, E., Lorenz, F., Flogegard, M., Marcher, C. W., oster Fernstrom, A., Cavelier, L., Papaemmanuil, E., Ebeling, F., Kittang, A. O., Norgaard, J. M., Saft, L. & 2 others, Mollgard, L. & Hellstrom-Lindberg, E., May 2022, In: Leukemia. 36, 5, p. 1436-1439 4 p.

Research output: Contribution to journal › Letter › Research › peer-review

A predictive model for bone marrow disease in cytopenia based on noninvasive procedures

Træden, D., Tulstrup, M., Cowland, J. B., Sjö, Lene Dissing, Bøgsted, M., Grønbæk, Kirsten, Andersen, M. K. & Hansen, J. W., 2022, In: Blood advances. 6, 11, p. 3541-3550

Research output: Contribution to journal › Journal article › Research › peer-review

Clonal Hematopoiesis and Epigenetic Age Acceleration in Elderly Danish Twins

Sørensen, M., Tulstrup, Morten Rytter, Hansen, Jakob Werner, Weischenfeldt, Joachim Lütken, Grønbæk, Kirsten & Christensen, K., 2022, In: HemaSphere. 6, 9, 6 p., 768.

Research output: Contribution to journal › Journal article › Research › peer-review

Clonal hematopoiesis is associated with hematological toxicity during lenalidomide-based therapy for MCL

Husby, Simon, Bæch-Laursen, C., Eskelund, C. W., Favero, Francesco, Jespersen, Jakob Schmidt, Hutchings, M., Pedersen, L. B., Niemann, Carsten, Weischenfeldt, Joachim Lütken, Räty, R., Larsen, T. S., Kolstad, A., Jerkeman, M. & Grønbæk, Kirsten, 2022, In: Leukemia. 36, p. 2912-2916

Research output: Contribution to journal › Journal article › Research › peer-review

Comprehensive and unbiased multiparameter high-throughput screening by compaRe finds effective and subtle drug responses in AML models

Chalabi Hajkarim, M., Karjalainen, E., Osipovitch, M., Dimopoulos, K., Gordon, Sandra, Ambri, F., Rasmussen, K. D., Grønbæk, Kirsten, Helin, K., Wennerberg, Krister & Won, K., 2022, In: eLife. 11, e73760.

Research output: Contribution to journal › Journal article › Research › peer-review

Epigenetic therapy in combination with a multi-epitope cancer vaccine targeting shared tumor antigens for high-risk myelodysplastic syndrome - a phase I clinical trial

Holmberg-Thydén, S., Dufva, I. H., Gang, Anne Ortved, Breinholt, M. F., Schejbel, L., Andersen, M. K., Kadivar, M., Svane, Inge Marie, Grønbæk, Kirsten, Hadrup, S. R. & El Fassi, D., 2022, In: Cancer Immunology, Immunotherapy. 71, p. 433-444

Research output: Contribution to journal › Journal article › Research › peer-review

Experiences and Needs of Caregivers of Adult Patients With Hematologic Malignancies During Treatment: A Qualitative Longitudinal Study

Husted Nielsen, I., Piil, K., Grønbæk, Kirsten, Kjeldsen, L. & Jarden, Mary Ellen, 2022, In: Cancer Nursing. 45, 5, p. E801-E809

Research output: Contribution to journal › Journal article › Research › peer-review

Family caregiver ambassador support for caregivers of patients with newly diagnosed hematological cancer: a feasibility study

Husted Nielsen, I., Piil, K., Tolver, Anders, Grønbæk, Kirsten, Kjeldsen, L. & Jarden, Mary Ellen, 2022, In: Supportive Care in Cancer. 30, 8, p. 6923-6935 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

How a Medical Association Can Make a Difference in a Crisis Situation

van Havre, N., Orsini, E., Almeida, A., Gribben, J., Bolanos, N., Doeswijk, R., Gaidano, G., Mouhssine, S., Doehner, K., Grønbæk, Kirsten, Porkka, K. & Macintyre, E., 2022, In: HemaSphere. 6, 9, 3 p., 765.

Research output: Contribution to journal › Editorial › Research › peer-review

Humoral response to two doses of BNT162b2 vaccination in people with HIV

Heftdal, Line Dam, Knudsen, A. D., Hamm, S. R., Hansen, Cecilie Bo, Møller, D. L., Pries-Heje, M., Fogh, K., Hasselbalch, R. B., Jarlhelt, I., Pérez-Alós, L., Hilsted, Linda, Ostrowski, Sisse Rye, Gerstoft, Jan, Grønbæk, Kirsten, Bundgård, Henning, Iversen, Kasper, Garred, Peter & Nielsen, Susanne Dam, 2022, In: Journal of Internal Medicine. 291, 4, p. 513-518

Research output: Contribution to journal › Journal article › Research › peer-review

Incidence of Positive Severe Acute Respiratory Syndrome Coronavirus Polymerase Chain Reaction After Coronavirus Disease 2019 Vaccination With up to 8 Months of Follow-up: Real-life Data From the Capital Region of Denmark

Heftdal, Line Dam, Schultz, M., Lange, Theis, Knudsen, A. D., Fogh, K., Hasselbalch, R. B., Linander, C. B., Kallemose, T., Bundgård, Henning, Grønbæk, Kirsten, Valentiner-Branth, P., Iversen, Kasper & Nielsen, Susanne Dam, 2022, In: Clinical Infectious Diseases. 75, 1, p. e675–e682 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Inflammatory Cytokine Profiles Do Not Differ Between Patients With Idiopathic Cytopenias of Undetermined Significance and Myelodysplastic Syndromes

Nielsen, A. B., Hansen, Jakob Werner, mxz703, mxz703, Dimopoulos, K., Salem, M., Grigorian, M., Bruunsgaard, Helle & Grønbæk, Kirsten, 2022, In: HemaSphere. 6, 5, 10 p., e0713.

Research output: Contribution to journal › Journal article › Research › peer-review

Level of unique T cell clonotypes is associated with clonal hematopoiesis and survival in patients with lymphoma undergoing ASCT

Husby, Simon, Jørgensen, G. Ø., Favero, Francesco, Jespersen, Jakob Schmidt, Rodriguez Gonzalez, Francisco G, Nielsen, C., Sorensen, B., Ebbesen, L. H., Bæch, J., Haastrup, E. K., Josefsson, P., Thorsgaard, M., Brown, Peter de Nully, El-Galaly, T. C., Larsen, T. S., Weischenfeldt, Joachim Lütken & Grønbæk, Kirsten, 2022, In: Bone Marrow Transplantation. 57, p. 674-677

Research output: Contribution to journal › Letter › Research › peer-review

Neoantigen reactive T cells correlate with the low mutational burden in hematological malignancies

Saini, S. K., Holmberg-Thydén, S., Bjerregaard, A. M., Unnikrishnan, A., Dorfmüller, S., Platzbecker, U., Tirado-Gonzalez, I., Bönig, H., Fassi, Daniel El , Grønbæk, Kirsten, Pimanda, J., Medyouf, H. & Hadrup, S. R., 2022, In: Leukemia. 36, 11, p. 2734-2738 5 p.

Research output: Contribution to journal › Letter › Research › peer-review

Pre-treatment health-related quality of life parameters have prognostic impact in patients >65 years with newly diagnosed mantle cell lymphoma: The Nordic Lymphoma Group MCL4 (LENA-BERIT) experience

Lindberg, Å., Eskelund, C. W., Albertsson-Lindblad, A., Kolstad, A., Laurell, A., Räty, R., Grønbæk, Kirsten, Geisler, C. H. & Jerkeman, M., 2022, In: Hematological Oncology. 40, 1, p. 23-31

Research output: Contribution to journal › Journal article › Research › peer-review

Safety, Outcomes, and T-Cell Characteristics in Patients with Relapsed or Refractory MDS or CMML Treated with Atezolizumab in Combination with Guadecitabine

O'Connell, C. L., Baer, M. R., Ørskov, A. D., Saini, S. K., Duong, V. H., Kropf, P., Hansen, J. W., Tsao-Wei, D., Jang, H. S., Emadi, A., Holmberg-Thyden, S., Cowland, J., Brinker, B. T., Horwood, K., Burgos, R., Hostetter, G., Youngblood, B. A., Hadrup, S. R., Issa, J. P., Jones, P. & 3 others, Baylin, S. B., Siddiqi, I. & Grønbæk, Kirsten, 2022, In: Clinical cancer research : an official journal of the American Association for Cancer Research. 28, 24, p. 5306-5316 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Serum proteome modulations upon treatment provides biological insight on response to treatment in relapsed mantle cell lymphoma

Lokhande, L., Kuci Emruli, V., Eskelund, C. W., Kolstad, A., Hutchings, M., Räty, R., Niemann, Carsten, Grønbæk, Kirsten, Jerkeman, M. & Ek, S., 2022, In: Cancer Reports. 5, 8 p., e1524.

Research output: Contribution to journal › Journal article › Research › peer-review

Socioeconomic position and clinical outcomes in patients with myelodysplastic syndromes: A population-based cohort study

Lauritsen, T. B., Østgård, L. S. G., Grønbæk, Kirsten, Dalton, Susanne Oksbjerg & Nørgaard, J. M., 2022, In: Hematological Oncology. 40, 5, p. 1056-1066

Research output: Contribution to journal › Journal article › Research › peer-review

The EHA Research Roadmap: Malignant Lymphoid Diseases

Dreyling, M., André, M., Gökbuget, N., Tilly, H., Jerkeman, M., Gribben, J., Ferreri, A., Morel, P., Stilgenbauer, S., Fox, C., Maria Ribera, J., Zweegman, S., Aurer, I., Bödör, C., Burkhardt, B., Buske, C., Dollores Caballero, M., Campo, E., Chapuy, B., Davies, A. & 34 others, De Leval, L., Doorduijn, J., Federico, M., Gaulard, P., Gay, F., Ghia, P., Grønbæk, Kirsten, Goldschmidt, H., Kersten, M. J., Kiesewetter, B., Landman-Parker, J., Le Gouill, S., Lenz, G., Leppä, S., Lopez-Guillermo, A., Macintyre, E., Mantega, M. V. M., Moreau, P., Moreno, C., Nadel, B., Okosun, J., Owen, R., Pospisilova, S., Pott, C., Robak, T., Spina, M., Stamatopoulos, K., Stary, J., Tarte, K., Tedeschi, A., Thieblemont, C., Trappe, R. U., Trümper, L. H. & Salles, G., 2022, In: HemaSphere. 6, 6, p. E726

Research output: Contribution to journal › Review › Research › peer-review

Therapeutic Potential of an Immune-Modulatory Vaccination Targeting Myeloid-Derived Suppressor Cells in Myelodysplastic Syndrome

Bentivegna, Sofia, Holmstrøm, M., Balhuizen, Alexander, Almosailleakh, M., Perez Penco, Maria, Porse, Bo Torben, Andersen, Mads Hald & Grønbæk, Kirsten, 2022, In: Blood. 140, Suppl. 1, p. 4007-4008 2 p.

Research output: Contribution to journal › Conference abstract in journal › Research

A user's guide to multicolor flow cytometry panels for comprehensive immune profiling

Holmberg-Thyden, S., Grønbæk, Kirsten, Gang, Anne Ortved, Fassi, Daniel El & Hadrup, S. R., 2021, In: Analytical Biochemistry. 627, 114210.

Research output: Contribution to journal › Journal article › Research › peer-review

Acute and persistent symptoms in non-hospitalized PCR-confirmed COVID-19 patients

Bliddal, S., Banasik, Karina, Pedersen, Ole Birger Vesterager, Nissen, J., Cantwell, Lisa, Schwinn, M., Tulstrup, Morten Rytter, Westergaard, David, Ullum, H., Brunak, Søren, Tommerup, Niels, Feenstra, B., Geller, F., Ostrowski, Sisse Rye, Grønbæk, Kirsten, Nielsen, Claus Henrik, Nielsen, Susanne Dam & Feldt-Rasmussen, Ulla, 2021, In: Scientific Reports. 11, 13153.

Research output: Contribution to journal › Journal article › Research › peer-review

Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Myelomonocytic Leukemia: Clinical and Molecular Genetic Prognostic Factors in a Nordic Population

Wedge, E., Hansen, J. W., Dybedal, I., Creignou, M., Ejerblad, E., Lorenz, F., Werlenius, O., Ungerstedt, J., Holm, M. S., Nilsson, L., Kittang, A. O., Antunovic, P., Rohon, P., Andersen, M. K., Papaemmanuil, E., Bernard, E., Jädersten, M., Hellström-Lindberg, E., Grønbæk, K., Ljungman, P. & 1 others, Friis, L. S., 2021, In: Transplantation and Cellular Therapy. 27, 12, p. 991.e1-991.e9

Research output: Contribution to journal › Journal article › Research › peer-review

Arvelig prædisposition til myeloid neoplasi hos voksne

Nitschke, N. J., Andersen, M. K. & Grønbæk, Kirsten, 2021, In: Ugeskrift for Laeger. 183, 42, V04210346.

Research output: Contribution to journal › Journal article › Research › peer-review

Detailed Long-Term Follow-Up of Patients Who Relapsed After the Nordic Mantle Cell Lymphoma Trials: MCL2 and MCL3

Eskelund, C. W., Dimopoulos, K., Kolstad, A., Glimelius, I., Räty, R., Gjerdrum, Lise Mette Rahbek, Sonnevi, K., Josefsson, P., Nilsson-ehle, H., Bentzen, H. H. N., Fagerli, U. M., Kuittinen, O., Haaber, J., Niemann, Carsten, Pedersen, L. B., Larsen, M. T., Geisler, C. H., Hutchings, M., Jerkeman, M. & Grønbæk, Kirsten, 2021, In: HemaSphere. 5, 1, p. 1-9 e510.

Research output: Contribution to journal › Journal article › Research › peer-review

Expression patterns and prognostic potential of circular RNAs in mantle cell lymphoma: a study of younger patients from the MCL2 and MCL3 clinical trials

Dahl, M., Husby, Simon, Eskelund, C. W., Besenbacher, S., Fjelstrup, S., Côme, Christophe Roger Michel, Ek, S., Kolstad, A., Räty, R., Jerkeman, M., Geisler, C. H., Kjems, J., Kristensen, L. S. & Grønbæk, Kirsten, 2021, In: Leukemia. 36, p. 177-188

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide circular rna expression patterns reflect resistance to immunomodulatory drugs in multiple myeloma cells

Jakobsen, T., Dahl, M., Dimopoulos, K., Grønbæk, Kirsten, Kjems, J. & Kristensen, L. S., 2021, In: Cancers. 13, 3, p. 1-19 19 p., 365.

Research output: Contribution to journal › Journal article › Research › peer-review

Mutations known from B-cell lymphoid malignancies are not found in CD34⁺ stem cells from patients with lymphoma

Husby, Simon, Favero, Francesco, Rodriguez Gonzalez, Francisco G, Sutton, L. A., Haastrup, E. K., mxz703, mxz703, Hansen, Jakob Werner, Arboe, B., Aslan, D., Clasen-Linde, E., Gjerdrum, Lise Mette Rahbek, Gørlev, J. S., Brown, Peter de Nully, Fischer-Nielsen, A., Rosenquist, R., Weischenfeldt, Joachim Lütken & Grønbæk, Kirsten, 2021, In: Leukemia and Lymphoma. 62, 11, p. 2808-2811

Research output: Contribution to journal › Journal article › Research › peer-review

Protein phosphatase, Mg2+/Mn2+-dependent 1D (PPM1D) mutations in haematological cancer

Husby, Simon, Justesen, E. H. & Grønbæk, Kirsten, 2021, In: British Journal of Haematology. 192, 4, p. 697-705 9 p.

Research output: Contribution to journal › Review › Research › peer-review

Risk of new malignancies among patients with CLL treated with chemotherapy: results of a Danish population-based study

da Cunha-Bang, C., Rostgaard, K., Andersen, M. A., Rotbain, E. C., Grønbæk, Kirsten, Frederiksen, H., Niemann, Carsten & Hjalgrim, Henrik, 2021, In: British Journal of Haematology. 193, 2, p. 339-345

Research output: Contribution to journal › Journal article › Research › peer-review

Socioeconomic Position and Risk of Disease Progression and Death in Patients with Myelodysplastic Syndromes: A Danish Nation-Wide Population-Based Cohort Study

Lauritsen, T. B., Oestgaard, L. S. G., Grønbæk, Kirsten, Dalton, Susanne Oksbjerg & Norgaard, J. M., 2021, In: Blood. 138, 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Structural aberrations are associated with poor survival in patients with clonal cytopenia of undetermined significance

Mikkelsen, Stine Ulrik, Safavi, S., Dimopoulos, K., O'Rourke, Colm, Andersen, M. K., Holm, M. S., Marcher, C. W., Andersen, Jesper Bøje, Hansen, Jakob Werner & Grønbæk, Kirsten, 2021, In: Haematologica. 106, 6

Research output: Contribution to journal › Comment/debate › Research › peer-review

TET2 mutations are associated with hypermethylation at key regulatory enhancers in normal and malignant hematopoiesis

Tulstrup, Morten Rytter, Soerensen, M., Hansen, Jakob Werner, Gillberg, Linn, Needhamsen, M., Kaastrup, K., Helin, K., Christensen, K., Weischenfeldt, Joachim Lütken & Grønbæk, Kirsten, 2021, In: Nature Communications. 12, 1, 10 p., 6061.

Research output: Contribution to journal › Journal article › Research › peer-review

The Danish Myelodysplastic Syndromes Database: Patient Characteristics and Validity of Data Records

Lauritsen, T. B., Nørgaard, J. M., Grønbæk, Kirsten, Vallentin, A. P., Ahmad, S. A., Hannig, L. H., Severinsen, M. T., Adelborg, K. & Østgård, L. S. G., 2021, In: Clinical Epidemiology. 13, p. 439-451 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Impact of Sedentary Lifestyle, High-fat Diet, Tobacco Smoke, and Alcohol Intake on the Hematopoietic Stem Cell Niches

Kaastrup, K. & Grønbæk, Kirsten, 2021, In: HemaSphere. 5, 8, p. 1-10 e615.

Research output: Contribution to journal › Review › Research › peer-review

The Thioredoxin-Interacting Protein TXNIP Is a Putative Tumour Suppressor in Cutaneous T-Cell Lymphoma

Stolearenco, V., Levring, T. B., Nielsen, H. M., Lindahl, L., Fredholm, S., Kongsbak-Wismann, Martin, Willerslev-Olsen, A., Buus, Terkild Brink, Nastasi, C., Hu, T., Gluud, Maria, Côme, Christophe Roger Michel, Krejsgaard, T., Iversen, L., Bonefeld, Charlotte Menne, Grønbæk, Kirsten, Met, Özcan, Woetmann, Anders , Ødum, Niels & Geisler, Carsten, 2021, In: Dermatology. 237, 2, p. 283-290 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The role of vitamin C in epigenetic cancer therapy

Mikkelsen, Stine Ulrik, Gillberg, Linn, Lykkesfeldt, Jens & Grønbæk, Kirsten, 2021, In: Free Radical Biology and Medicine. 170, p. 179-193 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Profiling of ribose methylations in ribosomal RNA from diffuse large B-cell lymphoma patients for evaluation of ribosomes as drug targets

Krogh, Nicolai, Asmar, F., Côme, Christophe Roger Michel, Fibiger Munch-Petersen, H., Grønbæk, Kirsten & Nielsen, Henrik, 4 Dec 2020, In: NAR Cancer. 2, 4, 11 p., zcaa035.

Research output: Contribution to journal › Journal article › Research › peer-review

Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers with low mutational burden

Saini, S. K., mxz703, mxz703, Bjerregaard, A., Unnikrishnam, A., Holmberg-Thyden, S., Borch, A., Anande, G., Bentzen, A., Marquard, A., Tamhane, T., Gang, Anne Ortved, Defva, I., Szallasi, Z., Eklund, A., Pimanda, J., Grønbæk, Kirsten & Hadrup, S., 1 May 2020, In: Journal of Immunology. 204, 1 supplement, 2 p., 242.14.

Research output: Contribution to journal › Conference abstract in journal › Research

Activation of a subset of evolutionarily young transposable elements and innate immunity are linked to clinical responses to 5-azacytidine

Ohtani, H., mxz703, mxz703, Helbo, A. S., Gillberg, Linn, Liu, M., Zhou, W., Ungerstedt, J., Hellström-Lindberg, E., Sun, W., Liang, G., Jones, P. A. & Grønbæk, Kirsten, 2020, In: Cancer Research. 80, 12, p. 2441-2450 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Angiotensinogen promoter methylation predicts bevacizumab treatment response of patients with recurrent glioblastoma

Urup, T., Gillberg, Linn, Kaastrup, K., Lü, M. J. S., Michaelsen, Signe Regner, Andrée Larsen, V., Christensen, I. J., Broholm, H., Lassen, Ulrik Niels, Grønbæk, Kirsten & Poulsen, H. S., 2020, In: Molecular Oncology. 14, 5, p. 964-973

Research output: Contribution to journal › Journal article › Research › peer-review

Cell‐of‐origin determined by both gene expression profiling and immunohistochemistry is the strongest predictor of survival in patients with diffuse large B‐cell lymphoma

Abdulla, M., Hollander, P., Pandzic, T., Mansouri, L., Ednersson, S. B., Andersson, P., Hultdin, M., Fors, M., Erlanson, M., Degerman, S., Petersen, H. M., Asmar, F., Grønbæk, Kirsten, Enblad, G., Cavelier, L., Rosenquist, R. & Amini, R., 2020, In: American Journal of Hematology. 95, 1, p. 57-67

Research output: Contribution to journal › Journal article › Research › peer-review

Clinical impact of clonal hematopoiesis in patients with lymphoma undergoing ASCT: a national population-based cohort study

Husby, S., Favero, F., Nielsen, C., Sørensen, B. S., Bæch, J., Grell, K., Hansen, J. W., Rodriguez-Gonzalez, F. G., Haastrup, E. K., Fischer-Nielsen, A., Andersen, P., Arboe, B., Sækmose, S. G., Hansen, P. B., Christiansen, I., Clasen-Linde, E., Meldgaard, L., Ebbesen, L. H., Segel, E. K., Josefsson, P. & 6 others, Thorsgaard, M., El-Galaly, T. C., Brown, Peter de Nully, Weischenfeldt, Joachim Lütken, Larsen, T. S. & Grønbæk, Kirsten, 2020, In: Leukemia. 34, p. 3256-3268 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Clonal hematopoiesis evolves from pretreatment clones and stabilizes after end of chemotherapy in patients with MCL

Eskelund, C. W., Husby, Simon, Favero, Francesco, Klausen, T. W., Rodriguez Gonzalez, Francisco G, Kolstad, A., Pedersen, L. B., Räty, R. K., Geisler, C. H., Jerkeman, M., Weischenfeldt, Joachim Lütken & Grønbæk, Kirsten, 2020, In: Blood. 135, 22, p. 2000-2004

Research output: Contribution to journal › Comment/debate › Research › peer-review

Clonal hematopoiesis in elderly twins: concordance, discordance, and mortality

Hansen, Jakob Werner, Pedersen, D. A., Larsen, L. A., Husby, Simon, Clemmensen, S. B., Hjelmborg, J., Favero, Francesco, Weischenfeldt, Joachim Lütken, Christensen, K. & Grønbæk, Kirsten, 2020, In: Blood. 135, 4, p. 261-268

Research output: Contribution to journal › Journal article › Research › peer-review

Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers

Saini, S. K., Ørskov, A. D., Bjerregaard, A. M., Unnikrishnan, A., Holmberg-Thydén, S., Borch, A., Jensen, K. V., Anande, G., Bentzen, A. K., Marquard, A. M., Tamhane, T., Treppendahl, M. B., Gang, A. O., Dufva, I. H., Szallasi, Z., Ternette, N., Pedersen, A. G., Eklund, A. C., Pimanda, J., Grønbæk, K. & 1 others, Hadrup, S. R., 2020, In: Nature Communications. 11, 1, 5660.

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of unique and shared mitochondrial DNA mutations in neurodegeneration and cancer by single-cell mitochondrial DNA structural variation sequencing (MitoSV-seq)

Jaberi, E., Tresse-Gommeaux, Emilie, Grønbæk, Kirsten, Weischenfeldt, Joachim Lütken & Issazadeh-Navikas, Shohreh, 2020, In: EBioMedicine. 57, p. 1-17 102868.

Research output: Contribution to journal › Journal article › Research › peer-review

Improved Outcomes after Allogenic Hematopoietic Stem Cell Transplantation with Fludarabine/Treosulfan for Patients with Myelodysplastic Syndromes

Wedge, E., Sengeløv, Henrik, Hansen, Jakob Werner, Andersen, N. S., Schjødt, I., Petersen, S. L., Kornblit, B., Grønbæk, Kirsten & Friis, L. S., 2020, In: Biology of Blood and Marrow Transplantation. 26, 6, p. 1091-1098

Research output: Contribution to journal › Journal article › Research › peer-review

KMT2D mutations and TP53 disruptions are poor prognostic biomarkers in mantle cell lymphoma receiving high-dose therapy: a FIL study

Ferrero, S., Rossi, D., Rinaldi, A., Bruscaggin, A., Spina, V., Eskelund, C. W., Evangelista, A., Moia, R., Kwee, I., Dahl, C., Di Rocco, A., Stefoni, V., Diop, F., Favini, C., Ghione, P., Mahmoud, A. M., Schipani, M., Kolstad, A., Barbero, D., Novero, D. & 13 others, Paulli, M., Zamò, A., Jerkeman, M., Gomez Da Silva, M., Santoro, A., Molinari, A., Ferreri, A., Grønbæk, Kirsten, Piccin, A., Cortelazzo, S., Bertoni, F., Ladetto, M. & Gaidano, G., 2020, In: Haematologica. 105, 6, p. 1604-1612

Research output: Contribution to journal › Journal article › Research › peer-review

The diagnostic and prognostic role of flow cytometry in idiopathic and clonal cytopenia of undetermined significance (ICUS/CCUS): A single-center analysis of 79 patients

Dimopoulos, K., Hansen, O. K., Sjö, Lene Dissing, Saft, L., Schjødt, I. M., Hansen, Jakob Werner & Grønbæk, Kirsten, 2020, In: Cytometry. Part B: Clinical Cytometry. 98, 3, p. 250-258

Research output: Contribution to journal › Journal article › Research › peer-review

The value of circulating microRNAs for early diagnosis of B-cell lymphoma: A case-control study on historical samples

Jørgensen, S., Paulsen, I. W., Hansen, Jakob Werner, Tholstrup, Dorte Maegaard, Hother, C., Sørensen, E., Petersen, M. S., Nielsen, K. R., Rostgaard, K., Larsen, M. A. H., Brown, Peter de Nully, Ralfkiær, E., Homburg, K. M., Hjalgrim, Henrik, Erikstrup, C., Ullum, H., Troelsen, J., Grønbæk, Kirsten & Pedersen, Ole Birger Vesterager, 2020, In: Scientific Reports. 10, 1, 9637.

Research output: Contribution to journal › Journal article › Research › peer-review

p53 is associated with high-risk and pinpoints TP53 missense mutations in mantle cell lymphoma

Rodrigues, J. M., Hassan, M., Freiburghaus, C., Eskelund, C. W., Geisler, C., Räty, R., Kolstad, A., Sundström, C., Glimelius, I., Grønbæk, Kirsten, Kwiecinska, A., Porwit, A., Jerkeman, M. & Ek, S., 2020, In: British Journal of Haematology. 191, 5, p. 796-805

Research output: Contribution to journal › Journal article › Research › peer-review

Increased neonatal level of arginase 2 in cases of childhood acute lymphoblastic leukemia implicates immunosuppression in the etiology

Nielsen, A. B., Zhou, M., de Smith, A. J., Wang, R., McCoy, L., Hansen, H., Morimoto, L., Grønbæk, Kirsten, Johansen, Christoffer, Kogan, S. C., Metayer, C., Bracci, P. M., Ma, X. & Wiemels, J. L., Nov 2019, In: Haematologica. 104, 11, p. e514-e516 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Oral vitamin C supplementation to patients with myeloid cancer on azacitidine treatment: Normalization of plasma vitamin C induces epigenetic changes

Gillberg, Linn, mxz703, mxz703, Nasif, A., Ohtani, H., Madaj, Z., Hansen, Jakob Werner, Rapin, N., Mogensen, J. B., Liu, M., Dufva, I. H., Lykkesfeldt, Jens, Hajkova, P., Jones, P. A. & Grønbæk, Kirsten, 17 Oct 2019, In: Clinical Epigenetics. 11, 1, p. 143-153 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Angiotensinogen promoter methylation to predict bevacizumab response in recurrent glioblastoma patients

Urup, T., Gillberg, Linn, Kaastrup, K., Lu, M. S., Michaelsen, Signe Regner, Larsen, V. A., Christensen, I. J., Broholm, H., Lassen, Ulrik Niels, Grønbæk, Kirsten & Poulsen, H. S., 2019, In: Neuro-Oncology. 21, Supplement 6, p. vi149

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Epigenetic therapy in hematological cancers

Dimopoulos, K. & Grønbæk, Kirsten, 2019, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 127, 5, p. 316-328 13 p.

Research output: Contribution to journal › Review › Research › peer-review

Expression of CRBN, IKZF1, and IKZF3 does not predict lenalidomide sensitivity and mutations in the cereblon pathway are infrequent in multiple myeloma

Dimopoulos, K., Fibiger Munch-Petersen, H., Winther Eskelund, C., Sjö, Lene Dissing, Ralfkiær, E., Gimsing, P. & Grønbæk, Kirsten, 2019, In: Leukemia and Lymphoma. 60, 1, p. 180-188

Research output: Contribution to journal › Journal article › Research › peer-review

Nordic Guidelines for Germline Predisposition to Myeloid Neoplasms in Adults: Recommendations for Genetic Diagnosis, Clinical Management and Follow-up

Baliakas, P., Tesi, B., Wartiovaara-kautto, U., Stray-pedersen, A., Friis, L. S., Dybedal, I., Hovland, R., Jahnukainen, K., Raaschou-Jensen, K., Ljungman, P., Rustad, C. F., Lautrup, C. K., Kilpivaara, O., Kittang, A. O., Grønbæk, Kirsten, Cammenga, J., Hellström-lindberg, E. & Andersen, M. K., 2019, In: HemaSphere. 3, 6, p. 1-10 e321.

Research output: Contribution to journal › Journal article › Research › peer-review

Enzyme-free digital counting of endogenous circular RNA molecules in B-cell malignancies

Dahl, M., Daugaard, I., Andersen, M. S., Hansen, T. B., Grønbæk, Kirsten, Kjems, J. & Kristensen, L. S., 1 Dec 2018, In: Laboratory Investigation. 98, 12, p. 1657-1669 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Vitamin C - A new player in regulation of the cancer epigenome

Gillberg, Linn, mxz703, mxz703, Liu, M., Harsløf, L. B. S., Jones, P. A. & Grønbæk, Kirsten, Aug 2018, In: Seminars in Cancer Biology. 51, p. 59-67

Research output: Contribution to journal › Review › Research › peer-review

Dual inhibition of DNMTs and EZH2 can overcome both intrinsic and acquired resistance of myeloma cells to IMiDs in a cereblon-independent manner

Dimopoulos, K., Søgaard Helbo, A., Fibiger Munch-Petersen, H., Sjö, Lene Dissing, Christensen, J., Sommer Kristensen, L., Asmar, F., Hermansen, N. E. U., O'Connel, C., Gimsing, P., Liang, G. & Grønbæk, Kirsten, Feb 2018, In: Molecular Oncology. 12, 2, p. 180-195

Research output: Contribution to journal › Journal article › Research › peer-review

Autoimmune Processes as an Important Parameter for the Pathogenesis of Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria

Kaastrup, K., Grønbæk, Kirsten, Hadrup, S. R. & Glenthoj, A., 2018, In: Journal of Blood & Lymph. 08, 02

Research output: Contribution to journal › Journal article › Research › peer-review

Bortezomib prevents cytarabine resistance in MCL, which is characterized by down-regulation of dCK and up-regulation of SPIB resulting in high NF-κB activity

Freiburghaus, C., Emruli, V. K., Johansson, A., Eskelund, C. W., Grønbæk, Kirsten, Olsson, R., Ek, F., Jerkeman, M. & Ek, S., 2018, In: BMC Cancer. 18, 1, 17 p., 466.

Research output: Contribution to journal › Journal article › Research › peer-review

Clinical Impact of Clonal Hematopoiesis after Autologous Stem Cell Transplantation for Lymphoma: A National Population-Based Cohort Study

Husby, S., Francesco, F., Nielsen, C., Sorensen, B., Baech, J., Hansen, J. W., Gonzalez, G. G. R., Arboe, B., Andersen, L. P., Hastrup, E. K., Fischer-Nielsen, A., Saekmose, S. G., Hansen, P. B., Christiansen, I., Clasen-Linde, E., Knudsen, L. M., Grell, K., Segel, E. K., Ebbesen, L. H., Thorsgaard, M. & 6 others, Josefsson, P. L., El-Galaly, T. C., Brown, Peter de Nully, Weisenfeldt, J., Larsen, T. S. & Grønbæk, Kirsten, 2018, In: Blood. 132, Suppl 1, p. 607 1 p.

Research output: Contribution to journal › Conference abstract in journal › Research

DNA methylation levels of the ELMO gene promoter CpG islands in human glioblastomas

Michaelsen, Signe Regner, Aslan, D., Urup, T., Poulsen, H. S., Grønbæk, Kirsten, Broholm, H. & Kristensen, L. S., 2018, In: International Journal of Molecular Sciences . 19, 3, 13 p., 679.

Research output: Contribution to journal › Journal article › Research › peer-review

Epidemiology of chronic red-cell transfusion recipients in Sweden and Denmark-a 10 year follow-up study

Didriksen, Maria, Rostgaard, K., Grønbæk, Kirsten, Pedersen, Ole Birger Vesterager, Titlestad, K., Erikstrup, C., Nielsen, K. R., Edgren, G., Ullum, H. & Hjalgrim, H., 2018, In: Vox Sanguinis. 113, 8, p. 770-778 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucin

Reckzeh, K., Kizilkaya, Hüsün Sheyma, Helbo, A. S., Estruch Alrich, Montserrat, Deslauriers, A. G., Grover, A., Rapin, N., Asmar, F., Grønbæk, Kirsten, Porse, Bo Torben, Borregaard, N., Vestweber, D., Nerlov, C. & Theilgaard-Mønch, Kim, 2018, In: Blood advances. 2, 13, p. 1628-1632 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Human endogenous retroviruses and their implication for immunotherapeutics of cancer

Attermann, A. S., Bjerregaard, A., Saini, S. K., Grønbæk, Kirsten & Hadrup, S. R., 2018, In: Annals of Oncology. 29, 11, p. 2183-2191 9 p.

Research output: Contribution to journal › Review › Research › peer-review

Ibrutinib, lenalidomide, and rituximab in relapsed or refractory mantle cell lymphoma (PHILEMON): a multicentre, open-label, single-arm, phase 2 trial

Jerkeman, M., Eskelund, C. W., Hutchings, M., Räty, R., Wader, K. F., Laurell, A., Toldbod, H., Pedersen, L. B., Niemann, Carsten, Dahl, C., Kuitunen, H., Geisler, C. H., Grønbæk, Kirsten & Kolstad, A., 2018, In: The Lancet Haematology. 5, 3, p. e109-e116 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Lenalidomide plus bendamustine-rituximab does not overcome the adverse impact of TP53 mutations in mantle cell lymphoma

Eskelund, C. W., Albertsson-Lindblad, A., Kolstad, A., Laurell, A., Räty, R., Pedersen, L. B., Geisler, C. H., Jerkeman, M. & Grønbæk, Kirsten, 2018, In: Haematologica. 103, 11, p. e541-e543 3 p.

Research output: Contribution to journal › Letter › Research › peer-review

Long Non-Coding RNAs Guide the Fine-Tuning of Gene Regulation in B-Cell Development and Malignancy

Dahl, M., Kristensen, L. S. & Grønbæk, Kirsten, 2018, In: International Journal of Molecular Sciences. 19, 9, 26 p., 2475.

Research output: Contribution to journal › Review › Research › peer-review

Long-term clinical outcomes of patients with hematologically unexplained cytopenia after routine assessment: A single center study

Johansen, M. M., Andersen, M. A., Grønbæk, Kirsten & Hansen, Jakob Werner, 2018, In: European Journal of Haematology. 101, 5, p. 595–603 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Mother–child transmission of epigenetic information by tunable polymorphic imprinting

Carpenter, B. L., Zhou, W., Madaj, Z., DeWitt, A. K., Ross, J. P., Grønbæk, Kirsten, Liang, G., Clark, S. J., Molloy, P. L. & Jones, P. A., 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 51, p. E11970-E11977 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Specific Lipid and Metabolic Profiles of R-CHOP-Resistant Diffuse Large B-Cell Lymphoma Elucidated by Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging and in Vivo Imaging

Barré, F. P. Y., Claes, B. S. R., Dewez, F., Peutz-Kootstra, C., Munch-Petersen, H. F., Grønbæk, Kirsten, Lund, Anders H., Heeren, R. M. A., Côme, Christophe Roger Michel & Cillero-Pastor, B., 2018, In: Analytical Chemistry. 90, 24, p. 14198-14206 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Twin DNA Methylation Profiling Reveals Flare-Dependent Interferon Signature and B Cell Promoter Hypermethylation in Systemic Lupus Erythematosus

Ulff-Møller, C. J., Asmar, F., Liu, Y., Svendsen, A. J., Busato, F., Grønbæk, Kirsten, Tost, J. & Jacobsen, Søren, 2018, In: Arthritis & rheumatology (Hoboken, N.J.). 70, 6, p. 878-890 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Mature lymphoid malignancies: origin, stem cells, and chronicity

Husby, Simon & Grønbæk, Kirsten, Nov 2017, In: Blood advances. 1, 25, p. 2444-2455 12 p.

Research output: Contribution to journal › Review › Research › peer-review

DNA Methyltransferase Inhibitors in Myeloid Cancer: Clonal Eradication or Clonal Differentiation?

mxz703, mxz703 & Grønbæk, Kirsten, Sep 2017, In: Cancer journal (Sudbury, Mass.). 23, 5, p. 277-285 9 p.

Research output: Contribution to journal › Review › Research › peer-review

Anemia is present years before myelodysplastic syndrome diagnosis: Results from the pre-diagnostic period

Hansen, Jakob Werner, Sandholdt, H., Siersma, Volkert Dirk, mxz703, mxz703, Holmberg, S., Bjerrum, O. W., Hasselbalch, Hans Carl, Olivarius, Niels de Fine, Grønbæk, Kirsten & Andersen, Christen Bertel L, Jul 2017, In: American Journal of Hematology. 92, 7, p. E130-E132 3 p.

Research output: Contribution to journal › Comment/debate › Research › peer-review

Global hypomethylation is an independent prognostic factor in diffuse large B cell lymphoma

Wedge, E., Hansen, Jakob Werner, Garde, C., Asmar, F., Tholstrup, Dorte Maegaard, Kristensen, S. S., Munch-Petersen, H. D., Ralfkiaer, E., Brown, Peter de Nully, Grønbæk, Kirsten & Kristensen, L. S., Jul 2017, In: American Journal of Hematology. 92, 7, p. 689-694 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

MicroRNA-210, MicroRNA-331, and MicroRNA-7 Are Differentially Regulated in Treated HIV-1–Infected Individuals and Are Associated With Markers of Systemic Inflammation

Ballegaard, V., Ralfkiaer, U., Pedersen, K. K., Hove, M., Koplev, S., Brændstrup, P., Ryder, L. P., Madsen, H. O., Gerstoft, Jan, Grønbæk, Kirsten & Nielsen, S. D., 1 Apr 2017, In: Journal of Acquired Immune Deficiency Syndromes. 74, 4, p. e104-e113

Research output: Contribution to journal › Journal article › Research › peer-review

Molecular Monitoring after Autologous Stem Cell Transplantation and Preemptive Rituximab Treatment of Molecular Relapse; Results from the Nordic Mantle Cell Lymphoma Studies (MCL2 and MCL3) with Median Follow-Up of 8.5 Years

Kolstad, A., Pedersen, L. B., Eskelund, C. W., Husby, S., Grønbæk, K., Jerkeman, M., Laurell, A., Räty, R., Elonen, E., Andersen, N. S., Brown, P. D. N., Kimby, E., Bentzen, H., Sundström, C., Ehinger, M., Karjalainen-Lindsberg, M. L., Delabie, J., Ralfkiær, E., Fagerli, U. M., Nilsson-Ehle, H. & 5 others, Lauritzsen, G. F., Kuittinen, O., Niemann, Carsten, Geisler, C. H. & the Nordic Lymphoma Group, T. N. L. G., Mar 2017, In: Biology of Blood and Marrow Transplantation. 23, 3, p. 428-435 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

TP53 mutations identify younger mantle cell lymphoma patients who do not benefit from intensive chemoimmunotherapy

Eskelund, C. W., Dahl, C., Hansen, Jakob Werner, Westman, M., Kolstad, A., Pedersen, L. B., Montano-Almendras, C. P., Husby, Simon, Freiburghaus, C., Ek, S., Vestergaard, Anja Holm, Niemann, Carsten, Raty, R., Brown, Peter de Nully, Geisler, C. H., Andersen, M. K., Guldberg, P., Jerkeman, M. & Grønbæk, Kirsten, 2017, In: Blood. 130, 17, p. 1903-1910 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Epigenetic changes in myelofibrosis: Distinct methylation changes in the myeloid compartments and in cases with ASXL1 mutations

Myrtue Nielsen, H., Andersen, Christen Bertel L, Westman, M., Sommer Kristensen, L., Asmar, F., Arvid Kruse, T., Thomassen, M., Stauffer Larsen, T., Skov, V., Lotte Hansen, L., Weis Bjerrum, O., Hasselbalch, Hans Carl, Punj, V. & Grønbæk, Kirsten, 2017, In: Scientific Reports. 7, 11 p., 6774.

Research output: Contribution to journal › Journal article › Research › peer-review

Nucleosome Positioning and NDR Structure at RNA Polymerase III Promoters

Helbo, A. S., Lay, F. D., Jones, P. A., Liang, G. & Grønbæk, Kirsten, 2017, In: Scientific Reports. 7, 11 p., 41947.

Research output: Contribution to journal › Journal article › Research › peer-review

Årsagen til uforklaret cytopeni kan ofte findes med fokuseret DNA-sekventering

Hansen, J. W., Husby, S. & Grønbæk, Kirsten, 2017, In: Ugeskrift for Laeger. 179, 25, 4 p., V03170179.

Research output: Contribution to journal › Journal article › Research › peer-review

Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma

Mansouri, L., Noerenberg, D., Young, E., Mylonas, E., Abdulla, M., Frick, M., Asmar, F., Ljungström, V., Schneider, M., Yoshida, K., Skaftason, A., Pandzic, T., Gonzalez, B., Tasidou, A., Waldhueter, N., Rivas-Delgado, A., Angelopoulou, M., Ziepert, M., Arends, C. M., Couronné, L. & 35 others, Lenze, D., Baldus, C. D., Bastard, C., Okosun, J., Fitzgibbon, J., Dörken, B., Drexler, H. G., Roos-Weil, D., Schmitt, C. A., Munch-Petersen, H. D., Zenz, T., Hansmann, M., Strefford, J. C., Enblad, G., Bernard, O. A., Ralfkiaer, E., Erlanson, M., Korkolopoulou, P., Hultdin, M., Papadaki, T., Grønbæk, Kirsten, Lopez-Guillermo, A., Ogawa, S., Küppers, R., Stamatopoulos, K., Stavroyianni, N., Kanellis, G., Rosenwald, A., Campo, E., Amini, R., Ott, G., Vassilakopoulos, T. P., Hummel, M., Rosenquist, R. & Damm, F., 8 Dec 2016, In: Blood. 128, 23, p. 2666-2670 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Mutations in idiopathic cytopenia of undetermined significance assist diagnostics and correlate to dysplastic changes

Hansen, Jakob Werner, Westman, M. K., Sjö, Lene Dissing, Saft, L., Sommer Kristensen, L., mxz703, mxz703, Treppendahl, M., Andersen, M. K. & Grønbæk, Kirsten, Dec 2016, In: American Journal of Hematology. 91, 12, p. 1234-1238 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

15-year follow-up of the Second Nordic Mantle Cell Lymphoma trial (MCL2): prolonged remissions without survival plateau

Eskelund, C. W., Kolstad, A., Jerkeman, M., Räty, R., Laurell, A., Eloranta, S., Smedby, K. E., Husby, S., Pedersen, L. B., Andersen, N. S., Eriksson, M., Kimby, E., Bentzen, H., Kuittinen, O., Lauritzsen, G. F., Nilsson-Ehle, H., Ralfkiaer, E., Ehinger, M., Sundström, C., Delabie, J. & 7 others, Karjalainen-Lindsberg, M., Workman, C. T., Garde, C., Elonen, E., Brown, Peter de Nully, Grønbæk, Kirsten & Geisler, C. H., Nov 2016, In: British Journal of Haematology. 175, 3, p. 410-418 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Vitamin C increases viral mimicry induced by 5-aza-2'-deoxycytidine

Liu, M., Ohtani, H., Zhou, W., mxz703, mxz703, Charlet, J., Zhang, Y. W., Shen, H., Baylin, S. B., Liang, G., Grønbæk, Kirsten & Jones, P. A., 13 Sep 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 37, 7 p., 10238-44.

Research output: Contribution to journal › Journal article › Research › peer-review

Immune Mechanisms in Myelodysplastic Syndrome

Glenthøj, A., mxz703, mxz703, Hansen, Jakob Werner, Hadrup, S. R., O'Connell, C. & Grønbæk, Kirsten, 15 Jun 2016, In: International Journal of Molecular Sciences (Online). 17, 6, 13 p., 944.

Research output: Contribution to journal › Review › Research › peer-review

TP53 hotspot mutations are predictive of survival in primary central nervous system lymphoma patients treated with combination chemotherapy

Munch-Petersen, H. D., Asmar, F., Dimopoulos, K., Areškevičiūtė, A., Brown, Peter de Nully, Girkov, M. S., Pedersen, A., Sjö, Lene Dissing, Heegaard, Steffen, Broholm, H., Kristensen, L. S., Ralfkiaer, E. & Grønbæk, Kirsten, 22 Apr 2016, In: Acta Neuropathologica Communications. 4, 13 p., 40.

Research output: Contribution to journal › Journal article › Research

Assessment of Quantitative and Allelic MGMT Methylation Patterns as a Prognostic Marker in Glioblastoma

Kristensen, L. S., Michaelsen, Signe Regner, Dyrbye, H., Aslan, D., Grunnet, K., Christensen, I. J., Poulsen, H. S., Grønbæk, Kirsten & Broholm, H., Mar 2016, In: Journal of Neuropathology and Experimental Neurology. 75, 3, p. 246-55 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Aberrant methylation of cell-free circulating DNA in plasma predicts poor outcome in diffuse large B cell lymphoma

Sommer Kristensen, L., Hansen, Jakob Werner, Kristensen, S. S., Tholstrup, D., Harsløf, L. B. S., Pedersen, Ole Birger Vesterager, Brown, Peter de Nully & Grønbæk, Kirsten, 2016, In: Clinical Epigenetics. 8, 11 p., 95.

Research output: Contribution to journal › Journal article › Research › peer-review

Lenalidomide-bendamustine-rituximab in untreated mantle cell lymphoma > 65 years with untreated mantle cell lymphoma

Albertsson-Lindblad, A., Kolstad, A., Laurell, A., Räty, R., Grønbæk, Kirsten, Sundberg, J., Pedersen, L. B., Ralfkiær, E., Karjalainen-Lindsberg, M., Sundström, C., Ehinger, M., Geisler, C. & Jerkeman, M., 2016, In: Blood. 128, 14, p. 1814-1820

Research output: Contribution to journal › Journal article › Research › peer-review

Tumor suppressor microRNAs are downregulated in myelodysplastic syndrome with spliceosome mutations

Aslan, D., Garde, C., Nygaard, M. K., Helbo, A. S., Dimopoulos, K., Hansen, Jakob Werner, Severinsen, M. T., Treppendahl, M. B., Sjö, Lene Dissing, Grønbæk, Kirsten & Sommer Kristensen, L., 2016, In: OncoTarget. 7, 9, p. 9951-63 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

MICRORNA 203 CONTROLS T-CELL LYMPHOMAGENESIS BY TARGETING IL-2 RECEPTOR SIGNALING

Ralfkiaer, U., Jansson, Martin David, Kopp, K., Willerslev-Olsen, A., Asmar, F., Krejsgaard, T., Brown, P., Gniadecki, R., Woetmann, Anders , Lund, Anders H., Ødum, Niels & Grønbæk, Kirsten, 22 Jun 2015, In: Haematologica. 100, supplement 1, p. 104-105 2 p., P317.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

miR-18b overexpression identifies mantle cell lymphoma patients with poor outcome and improves the MIPI-B prognosticator

Husby, S., Ralfkiaer, U., Garde, C., Zandi, R., Ek, S., Kolstad, A., Jerkeman, M., Laurell, A., Räty, R., Pedersen, L. B., Pedersen, A., Ehinger, M., Sundström, C., Karjalainen-Lindsberg, M-L., Delabie, J., Clasen-Linde, E., Brown, P. D. N., Cowland, J. B., Workman, C. T., Geisler, C. H. & 1 others, Grønbæk, Kirsten, 23 Apr 2015, In: Blood. 125, 17, p. 2669-77 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Differential Expression of miR-155 and miR-21 in Tumor and Stroma Cells in Diffuse Large B-Cell Lymphoma

Munch-Petersen, H. D., Ralfkiaer, U., Sjö, Lene Dissing, Hother, C., Asmar, F., Nielsen, B. S., Brown, P., Ralfkiaer, E. & Grønbæk, Kirsten, Mar 2015, In: Applied Immunohistochemistry & Molecular Morphology. 23, 3, p. 188-195 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Loss of PRDM11 promotes MYC-driven lymphomagenesis

Fog-Tonnesen, C. K., Asmar, F., Côme, Christophe Roger Michel, Jensen, K. T., Johansen, Jens Vilstrup, Bou Kheir, T., Jacobsen, L., Friis, C., Louw, A., Rosgaard, L., Øbro, N. F., Marquart, Hanne Vibeke Hansen, Anthonsen, K., Braat, A. K., van Lohuizen, M., Ralfkiaer, E., Grønbæk, Kirsten & Lund, Anders H., 19 Feb 2015, In: Blood. 125, 8, p. 1272-81 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Development and blind clinical validation of a microRNA based predictor of response to treatment with R-CHO(E)P in DLBCL

Knudsen, S., Hother, C., Grønbæk, Kirsten, Jensen, T., Hansen, A., Mazin, W., Dahlgaard, J., Møller, M. B., Ralfkiær, E. & Brown, P. D. N., 2015, In: P L o S One. 10, 2, 15 p., e0115538.

Research output: Contribution to journal › Journal article › Research › peer-review

Hypermethylation of the VTRNA1-3 Promoter is Associated with Poor Outcome in Lower Risk Myelodysplastic Syndrome Patients

Helbo, A. S., Treppendahl, M. B., Aslan, D., Dimopoulos, K., Nandrup-Bus, C., Holm, M. S., Andersen, M. K., Liang, G., Sommer Kristensen, L. & Grønbæk, Kirsten, 2015, In: Genes. 6, 4, p. 977-90 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Hypomethylation and up-regulation of PD-1 in T cells by azacytidine in MDS/AML patients: A rationale for combined targeting of PD-1 and DNA methylation

mxz703, mxz703, Treppendahl, M. B., Skovbo, A., Holm, M. S., Friis, L. S., Hokland, M. & Grønbæk, Kirsten, 2015, In: OncoTarget. 6, 11, p. 9612-26 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Whole-exome sequencing and genome-wide methylation analyses identify novel disease associated mutations and methylation patterns in idiopathic hypereosinophilic syndrome

Andersen, Christen Bertel L, Nielsen, H. M., Sommer Kristensen, L., Helbo, A. S., Vikeså, J., Jønson, L., Nielsen, Finn Cilius, Hasselbalch, Hans Carl, Bjerrum, O. W., Punj, V. & Grønbæk, Kirsten, 2015, In: OncoTarget. 6, 38, p. 40588-97 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

MicroRNA expression in early mycosis fungoides is distinctly different from atopic dermatitis and advanced cutaneous T-cell lymphoma

Ralfkiaer, U., Lindahl, L. M., Litman, Thomas, Gjerdrum, Lise Mette Rahbek, Ahler, C. B., Gniadecki, R., Marstrand, T., Fredholm, S., Iversen, L., Wasik, M. A., Bonefeld, Charlotte Menne, Geisler, Carsten, Krejsgaard, T., Glue, C., Røpke, M. A., Woetmann, A., Skov, Lone, Grønbæk, Kirsten & Ødum, Niels, Dec 2014, In: Anticancer Research. 34, 12, p. 7207-17 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A Dual Program for Translation Regulation in Cellular Proliferation and Differentiation

Gingold, H., Tehler, D., Christoffersen, N. R., Nielsen, M. M., Asmar, F., Kooistra, S. M., Christophersen, N. S., Christensen, L. L., Borre, M., Sørensen, K. D., Andersen, L. D., Andersen, C. L., Hulleman, E., Wurdinger, T., Ralfkiær, E., Helin, K., Grønbæk, K., Orntoft, T., Waszak, S. M., Dahan, O. & 3 others, Pedersen, J. S., Lund, Anders H. & Pilpel, Y., 11 Sep 2014, In: Cell. 158, 6, p. 1281-92 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Circulating YKL-40 in patients with essential thrombocythemia and polycythemia vera treated with the novel histone deacetylase inhibitor vorinostat

Andersen, C. L., Bjørn, M. E., McMullin, M. F., Harrison, C., Samuelsson, J., Ejerblad, E., Zweegman, S., Fernandes, S., Bareford, D., Knapper, S., Löfvenberg, E., Linder, O., Andreasson, B., Ahlstrand, E., Jensen, M. K., Bjerrum, O. W., Vestergaard, H., Larsen, H., Klausen, T. W., Mourits-Andersen, T. & 5 others, Skov, V., Thomassen, M., Kruse, T., Grønbæk, Kirsten & Hasselbalch, H. C., Jul 2014, In: Leukemia Research. 38, 7, p. 816-821 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

SOX11 and TP53 add prognostic information to MIPI in a homogenously treated cohort of mantle cell lymphoma – a Nordic Lymphoma Group study

Nordström, L., Sernbo, S., Eden, P., Grønbæk, Kirsten, Kolstad, A., Räty, R., Karjalainen, M., Geisler, C., Ralfkiaer, E., Sundström, C., Laurell, A., Delabie, J., Ehinger, M., Jerkeman, M. & Ek, S., Jul 2014, In: British Journal of Haematology. 166, 1, p. 98-108 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Diffuse large B-cell lymphoma with combined TP53 mutation and MIR34A methylation: Another “double hit” lymphoma with very poor outcome?

Asmar, F., Hother, C., Kulosman, G., Treppendahl, M. B., Nielsen, H. M., Ralfkiaer, U., Pedersen, A., Møller, M. B., Ralfkiaer, E., de Nully Brown, P. & Grønbæk, Kirsten, 15 Apr 2014, In: OncoTarget. 5, 7, p. 1912-25 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Predicting response to epigenetic therapy

Treppendahl, M. B., Sommer Kristensen, L. & Grønbæk, Kirsten, Jan 2014, In: The Journal of Clinical Investigation. 124, 1, p. 47-55 9 p.

Research output: Contribution to journal › Review › Research › peer-review

5-Azacytidine treatment sensitizes tumor cells to T-cell mediated cytotoxicity and modulates NK cells in patients with myeloid malignancies

Gang, A. O., Frøsig, T. M., Brimnes, M. K., Lyngaa, R., Treppendahl, M. B., Grønbæk, Kirsten, Dufva, I. H., Straten, P. T. & Hadrup, S. R., 2014, In: Blood Cancer Journal. 4, 3, p. 1-9 9 p., e197.

Research output: Contribution to journal › Journal article › Research › peer-review

A novel del(8)(q23.2q24.11) contributing to disease progression in a case of JAK2/TET2 double mutated chronic myelomonocytic leukemia

Toft-Petersen, M., Kjeldsen, E., Nederby, L., Grønbæk, Kirsten, Hokland, P. & Roug, A. S., 2014, In: Leukemia Research Reports. 3, 2, p. 94-97 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Hypermethylation of DAPK1 is an independent prognostic factor predicting survival in diffuse large B-cell lymphoma

Kristensen, L. S., Asmar, F., Dimopoulos, K., Nygaard, M. K., Aslan, D., Hansen, Jakob Werner, Ralfkiaer, E. & Grønbæk, Kirsten, 2014, In: OncoTarget. 5, 20, p. 9798-810 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Limited clinical efficacy of azacitidine in transfusion-dependent, growth factor-resistant, low- and Int-1-risk MDS: Results from the nordic NMDSG08A phase II trial

Holm, M., Dybedahl, I., Holm, M., Karimi, M., Brandefors, L., Garelius, H., Grövdal, M., Dufva, I. H., Grønbæk, Kirsten, Jansson, M., Marcher, C., Nilsson, L., Kittang, A. O., Porwit, A., Saft, L., Möllgård, L. & Hellström-Lindberg, E., 2014, In: Pediatric Blood & Cancer. 4, 3, p. 1-7 7 p., e189.

Research output: Contribution to journal › Journal article › Research › peer-review

Nordic MCL3 study: ⁹⁰Y-ibritumomab-tiuxetan added to BEAM/C in non-CR patients before transplant in mantle cell lymphoma

Kolstad, A., Laurell, A., Jerkeman, M., Grønbæk, K., Elonen, E., Räty, R., Pedersen, L. B., Loft, A., Bogsrud, T. V., Kimby, E., Hansen, P. B., Fagerli, U-M., Nilsson-Ehle, H., Lauritzsen, G. F., Lehmann, A. K., Sundstrom, C., Karjalainen-Lindsberg, M-L., Ralfkiaer, E., Ehinger, M., Delabie, J. & 7 others, Bentzen, H., Schildt, J., Kostova-Aherdan, K., Frederiksen, H., Brown, P. D. N., Geisler, C. H. & Nordic Lymphoma Group, N. L. G., 2014, In: Blood. 123, 19, p. 2953 - 2959 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Paraneoplastisk pancytopeni hos en patient med uerkendt lungecancer

Hansen, J. W., Sjö, L. & Grønbæk, Kirsten, 2014, In: Ugeskrift for Laeger. 176, 19, p. 2-3 2 p., V11130675.

Research output: Contribution to journal › Journal article › Research › peer-review