Joshua Mark Brickman

Joshua Mark Brickman

Professor

Member of:

    ORCID: 0000-0003-1580-7491

    Publication year:
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    1 - 50 out of 50Page size: 50
    1. 2024
    2. Published

      Transcription factor co-expression mediates lineage priming for embryonic and extra-embryonic differentiation

      Redó-Riveiro, A., Al-Mousawi, J., Linneberg-Agerholm, Madeleine, Proks, Martin, Perera Pérez, Marta, Salehin, S M Nazmus & Brickman, Joshua Mark, 2024, In: Stem Cell Reports. 19, 2, p. 174-186 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. 2023
    4. Published

      In vitro models of human hypoblast and mouse primitive endoderm

      Perera Pérez, Marta & Brickman, Joshua Mark, 2023, In: Current Opinion in Genetics and Development. 83, 11 p., 102115.

      Research output: Contribution to journal › Review › Research › peer-review

    5. Published

      A bipartite function of ESRRB can integrate signaling over time to balance self-renewal and differentiation

      Knudsen, Teresa Emmilie Toudal, Hamilton, W. B., Proks, Martin, Lykkegaard, M., Linneberg-Agerholm, Madeleine, Nielsen, Alexander Valentin, Perera Pérez, Marta, Malzard, L. L., Trusina, Ala & Brickman, Joshua Mark, 2023, In: Cell Systems. 14, 9, p. 788-805.e8

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Expansion of ventral foregut is linked to changes in the enhancer landscape for organ-specific differentiation

      Wong, Yan Fung, Kumar, Y., Proks, Martin, Herrera, J. A. R., Rothová, M. M., S. Monteiro, Rita, Pozzi, S., Jennings, R. E., Hanley, N. A., Bickmore, W. A. & Brickman, Joshua Mark, 2023, In: Nature Cell Biology. 25, p. 481-492

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Neighbor-specific gene expression revealed from physically interacting cells during mouse embryonic development

      Kim, Junil, Rothová, M. M., Madan, E., Rhee, S., Weng, Guangzheng, Palma, A. M., Liao, Linbu, David, E., Amit, I., Hajkarim, M. C., Vudatha, V., Gutiérrez-García, A., Moreno, E., Winn, R., Trevino, J., Fisher, P. B., Brickman, Joshua Mark, Gogna, R. & Won, K. J., 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 2, 10 p., e2205371120.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Symmetric inheritance of parental histones governs epigenome maintenance and embryonic stem cell identity

      Wenger, Alice, Biran, Alva Ada, Alcaraz, N., Redó-Riveiro, A., Sell, Annika Charlotte, Krautz, Robert, Flury, Valentin, Reveron-Gomez, Nazaret, Solis-Mezarino, V., Völker-Albert, M., Imhof, A., Andersson, Robin, Brickman, Joshua Mark & Groth, Anja, 2023, In: Nature Genetics. 55, 9, p. 1567-1578 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. 2022
    10. Published

      Transcriptional heterogeneity and cell cycle regulation as central determinants of Primitive Endoderm priming

      Perera Pérez, Marta, Nissen, Silas Boye, Proks, Martin, Pozzi, S., S. Monteiro, Rita, Trusina, Ala & Brickman, Joshua Mark, 15 Aug 2022, In: eLife. 11, 23 p., e78967.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Cell-state transitions and collective cell movement generate an endoderm-like region in gastruloids

      Hashmi, A., Tlili, S., Perrin, P., Lowndes, Molly, Peradziryi, H., Brickman, Joshua Mark, Martínez Arias, A. & Lenne, P. F., 2022, In: eLife. 11

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Differentiation and Expansion of Human Extra-Embryonic Endoderm Cell Lines from Naïve Pluripotent Stem Cells

      Linneberg-Agerholm, Madeleine & Brickman, Joshua Mark, 2022, Methods in Molecular Biology. Humana Press, p. 105-116 12 p. (Methods in Molecular Biology, Vol. 2416).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    13. Published

      Evolutionary origin of vertebrate OCT4/POU5 functions in supporting pluripotency

      Sukparangsi, W., Morganti, E., Lowndes, Molly, Mayeur, H., Weisser, Melanie, Hammachi, F., Peradziryi, H., Roske, F., Hölzenspies, J., Livigni, A., Godard, B. G., Sugahara, F., Kuratani, S., Montoya, Guillermo, Frankenberg, S. R., Mazan, S. & Brickman, Joshua Mark, 2022, In: Nature Communications. 13, 1, 21 p., 5537.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Identification of the central intermediate in the extra-embryonic to embryonic endoderm transition through single-cell transcriptomics

      Rothová, M. M., Nielsen, Alexander Valentin, Proks, Martin, Wong, Yan Fung, Riveiro, A. R., Linneberg-Agerholm, Madeleine, David, E., Amit, I., Trusina, Ala & Brickman, Joshua Mark, 2022, In: Nature Cell Biology. 24, 6, p. 833-844 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Long-term feeder-free culture of human pancreatic progenitors on fibronectin or matrix-free polymer potentiates β cell differentiation

      Nakamura, A., Wong, Yan Fung, Venturato, A., Michaut, Magali, Venkateswaran, S., Santra, M., Gonçalves, C., Larsen, M., Leuschner, M., Kim, Y. H., Brickman, Joshua Mark, Bradley, M. & Grapin-Botton, A., 2022, In: Stem Cell Reports. 17, 5, p. 1215-1228 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Neighbor-specific gene expression revealed from physically interacting cells during mouse embryonic development

      Kim, Junil, Rothová, M. M., Liao, Linbu, Rhee, S., Weng, Guangzheng, David, E., Amit, I., Hajkarim, M. C., Brickman, Joshua Mark & Won, K. J., 2022, Cold Spring Harbor Laboratory, 26 p. (bioRxiv).

      Research output: Working paper › Preprint › Research

    17. 2021
    18. Published

      Changes in Cell Morphology and Actin Organization in Embryonic Stem Cells Cultured under Different Conditions

      Farhangibarooji, Younes, Hvid, K. G., Petitjean, I. I., Brickman, Joshua Mark, Oddershede, L. B. & Bendix, Poul Martin, 2021, In: Cells. 10, 11, 16 p., 2859.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Enhancers are activated by p300/CBP activity-dependent PIC assembly, RNAPII recruitment, and pause release

      Narita, Takeo, Ito, S., Higashijima, Y., Chu, W. K., Neumann, K., Walter, Jonas, Satpathy, S., Liebner, Tim, Hamilton, W. B., Maskey, E., Prus, G., Shibata, M., Iesmantavicius, V., Brickman, Joshua Mark, Anastassiadis, K., Koseki, H. & Choudhary, Chunaram, 2021, In: Molecular Cell. 81, 10, p. 2166-2182.e6

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. 2020
    21. Published

      From pluripotency to totipotency: an experimentalist's guide to cellular potency

      Riveiro, A. R. & Brickman, Joshua Mark, Aug 2020, In: Development. 147, 16, 11 p., 189845.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Can a Cell Put Its Arms around a Memory?

      Knudsen, Teresa Emmilie Toudal & Brickman, Joshua Mark, 7 May 2020, In: Cell Stem Cell. 26, 5, p. 609-610 2 p.

      Research output: Contribution to journal › Editorial › Research › peer-review

    23. 2019
    24. Published

      Naïve human pluripotent stem cells respond to Wnt, Nodal and LIF signalling to produce expandable naïve extra-embryonic endoderm

      Linneberg-Agerholm, Madeleine, Wong, Yan Fung, Romero Herrera, J. A., S. Monteiro, Rita, Anderson, K. G. V. & Brickman, Joshua Mark, 16 Dec 2019, In: Development (Cambridge, England). 146, 24, 15 p., 180620.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Genetic Deletion of Hesx1 Promotes Exit from the Pluripotent State and Impairs Developmental Diapause

      Pozzi, S., Bowling, S., Apps, J., Brickman, Joshua Mark, Rodriguez, T. A. & Martinez-Barbera, J. P., 10 Dec 2019, In: Stem Cell Reports. 13, 6, p. 970-979 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      An automated microfluidic device for time-lapse imaging of mouse embryonic stem cells

      Laing, A. F., Tirumala, V., Hegarty, E., Mondal, S., Zhao, P., Hamilton, W. B., Brickman, Joshua Mark & Ben-Yakar, A., Sep 2019, In: Biomicrofluidics. 13, 5, 054102.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Dynamic lineage priming is driven via direct enhancer regulation by ERK

      Hamilton, W. B., Mosesson, Y., S. Monteiro, Rita, Emdal, Kristina Bennet, Knudsen, Teresa Emmilie Toudal, Francavilla, C., Barkai, N., Olsen, Jesper Velgaard & Brickman, Joshua Mark, 2019, In: Nature. 575, p. 355-360

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. 2018
    29. Published

      HHEX is a transcriptional regulator of the VEGFC/FLT4/PROX1 signaling axis during vascular development.

      Gauvrit, S., Villasenor, A., Strilic, B., Kitchen, P., Collins, M. M., Marin-Juez, R., Guenther, S., Maischein, H., Fukuda, N., Canham, M. A., Brickman, Joshua Mark, Bogue, C. W., Jayaraman, P. & Stainier, D. Y. R., 2018, In: Nature Communications. 9, 1, 14 p., 2704.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome

      Weinert, B. T., Narita, Takeo, Satpathy, S., Srinivasan, B., Hansen, B. K., Schölz, C., Hamilton, W. B., Zucconi, B. E., Wang, W. W., Liu, W. R., Brickman, Joshua Mark, Kesicki, E. A., Lai, A., Bromberg, K. D., Cole, P. A. & Choudhary, Chunaram, 2018, In: Cell. 174, 1, p. 231-244.e12 27 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. 2017
    32. Published

      Four simple rules that are sufficient to generate the mammalian blastocyst

      Nissen, Silas Boye, Perera Pérez, Marta, Martin Gonzalez, Javier, Morgani, S. M. C., Jensen, Mogens Høgh, Sneppen, Kim, Brickman, Joshua Mark & Trusina, Ala, 12 Jul 2017, In: PLOS Biology. 15, 7, p. 1-30 e2000737.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Transcriptional Regulation of Hhex in Hematopoiesis and Hematopoietic Stem Cell Ontogeny

      Portero Migueles, R., Shaw, L., Rodrigues, N. P., May, G., Henseleit, K., Anderson, K. G. V., Goker, H., Jones, C. M., de Bruijn, M. F. T. R., Brickman, Joshua Mark & Enver, T., 9 Feb 2017, In: Developmental Biology. 424, 2, p. 236-245 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Properties of embryoid bodies

      Brickman, Joshua Mark & Serup, Palle, Feb 2017, In: Developmental Biology. 6, 2, 11 p., e259.

      Research output: Contribution to journal › Review › Research › peer-review

    35. Published

      Surveillance for Secure Differentiation

      Hamilton, W. B. & Brickman, Joshua Mark, 5 Jan 2017, In: Cell Stem Cell. 20, 1, p. 3-5 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Insulin fine-tunes self-renewal pathways governing naive pluripotency and extra-embryonic endoderm

      Anderson, K. G. V., Hamilton, W. B., Roske, F. V., Azad, A., Knudsen, Teresa Emmilie Toudal, Canham, M., Forrester, L. M. & Brickman, Joshua Mark, 2017, In: Nature Cell Biology. 19, 10, p. 1164-1177

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. 2016
    38. Published

      Polycomb enables primitive endoderm lineage priming in embryonic stem cells

      Illingworth, R. S., Hölzenspies, J. J., Roske, F. V., Bickmore, W. A. & Brickman, Joshua Mark, 10 Oct 2016, In: eLife. 5, 28 p., e14926.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Embryonic Stem Cell Culture Conditions Support Distinct States Associated with Different Developmental Stages and Potency

      Martin Gonzalez, Javier, Morgani, S. M., Bone, Robert Alexander, Bonderup, K., Abelechian, Sahar, Brakebusch, Cord Herbert & Brickman, Joshua Mark, 9 Aug 2016, In: Stem Cell Reports. 7, 2, p. 177-91 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Optical quantification of forces at play during stem cell differentiation

      Ritter, C., Brickman, Joshua Mark & Oddershede, L. B., 4 Mar 2016, In: Proceedings of S P I E - International Society for Optical Engineering. 9764, UNSP 97640J.

      Research output: Contribution to journal › Conference article › Research › peer-review

    41. Published

      Differentiation of Mouse Embryonic Stem Cells into Ventral Foregut Precursors

      Rothová, M., Hölzenspies, J. J., Livigni, A., Villegas, S. N. & Brickman, Joshua Mark, 3 Feb 2016, In: Current Protocols in Stem Cell Biology. 36, p. 1G.3.1-12

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Erratum to: Resolving Heterogeneity: Fluorescence-Activated Cell Sorting of Dynamic Cell Populations from Feeder-Free Mouse Embryonic Stem Cell Culture

      Holzenspies, J., dela Cruz, Gelo & Brickman, Joshua Mark, 2016, In: Methods in Molecular Biology. 1341, p. 445 1 p.

      Research output: Contribution to journal › Comment/debate › Research

    43. Published

      Resolving Heterogeneity: Fluorescence-Activated Cell Sorting of Dynamic Cell Populations from Feeder-Free Mouse Embryonic Stem Cell Culture

      Hölzenspies, J., dela Cruz, Gelo & Brickman, Joshua Mark, 2016, Embryonic Stem Cell Protocols. Turksen, K. (ed.). Springer, Vol. 1341. p. 25-40 16 p. (Methods in Molecular Biology, Vol. 134).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    44. 2015
    45. Published

      LIF supports primitive endoderm expansion during pre-implantation development

      Morgani, S. M. & Brickman, Joshua Mark, 15 Oct 2015, In: Development (Cambridge, England). 142, 20, p. 3488-99 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Gro/TLE enables embryonic stem cell differentiation by repressing pluripotent gene expression

      Laing, A. F., Lowell, S. & Brickman, Joshua Mark, 1 Jan 2015, In: Developmental Biology. 397, 1, p. 56-66 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. 2014
    48. Published

      Erk signaling suppresses embryonic stem cell self-renewal to specify endoderm

      Hamilton, W. B. & Brickman, Joshua Mark, 24 Dec 2014, In: Cell Reports. 9, 6, p. 2056-70 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      The molecular underpinnings of totipotency

      Morgani, S. M. C. & Brickman, Joshua Mark, 27 Oct 2014, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 369, 1657

      Research output: Contribution to journal › Review › Research › peer-review

    50. Published

      The POU-er of gene nomenclature

      Frankenberg, S. R., Frank, D., Harland, R., Johnson, A. D., Nichols, J., Niwa, H., Schöler, H. R., Tanaka, E., Wylie, C. & Brickman, Joshua Mark, Aug 2014, In: Development (Cambridge, England). 141, 15, p. 2921-3 3 p.

      Research output: Contribution to journal › Review › Research › peer-review

    51. 2013
    52. Published

      PI3K/Akt1 signalling specifies foregut precursors by generating regionalized extra-cellular matrix

      Villegas, S. N., Rothová, M., Barrios-Llerena, M. E., Pulina, M., Hadjantonakis, A., Le Bihan, T., Astrof, S. & Brickman, Joshua Mark, 24 Dec 2013, In: eLife. 2, 0, p. e00806 eLife 2013;2:e00806.

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. Published

      Survival of the fattest

      Morgani, S. M. & Brickman, Joshua Mark, 26 Nov 2013, In: eLife. 2, p. e01760

      Research output: Contribution to journal › Review › Research › peer-review

    54. Published

      A conserved Oct4/POUV-dependent network links adhesion and migration to progenitor maintenance

      Livigni, A., Peradziryi, H., Sharov, A. A., Chia, G., Hammachi, F., Migueles, R. P., Sukparangsi, W., Pernagallo, S., Bradley, M., Nichols, J., Ko, M. S. H. & Brickman, Joshua Mark, 18 Nov 2013, In: Current biology : CB. 23, 22, p. 2233-44 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    55. Published

      Oct4: the final frontier, differentiation defining pluripotency

      Livigni, A. & Brickman, Joshua Mark, 24 Jun 2013, In: Developmental Cell. 25, 6, p. 547-8 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    56. Published

      Totipotent Embryonic Stem Cells Arise in Ground-State Culture Conditions

      Morgani, S. M., Canham, M. A., Nichols, J., Sharov, A. A., Migueles, R. P., Ko, M. S. H. & Brickman, Joshua Mark, 4 Jun 2013, In: Cell Reports. p. 1945–1957

      Research output: Contribution to journal › Journal article › Research › peer-review

    57. 2012
    58. Published

      Transcriptional activation by Oct4 is sufficient for the maintenance and induction of pluripotency

      Hammachi, F., Morrison, G. M., Sharov, A. A., Livigni, A., Narayan, S., Papapetrou, E. P., O'Malley, J., Kaji, K., Ko, M. S. H., Ptashne, M. & Brickman, Joshua Mark, 23 Feb 2012, In: Cell Biology International Reports. 1, 2, p. 99-109 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    59. HOXB4 can enhance the differentiation of embryonic stem cells by modulating the hematopoietic niche

      Jackson, M., Axton, R. A., Taylor, A. H., Wilson, J. A., Gordon-Keylock, S. A. M., Kokkaliaris, K. D., Brickman, Joshua Mark, Schulz, H., Hummel, O., Hubner, N. & Forrester, L. M., Feb 2012, In: Stem Cells. 30, 2, p. 150-60 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    60. 2011
    61. Published

      Gene expression heterogeneities in embryonic stem cell populations: origin and function

      Martinez Arias, A. & Brickman, Joshua Mark, Dec 2011, In: Current Opinion in Cell Biology. 23, 6, p. 650-6 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    62. 2003
    63. Published

      Characterizing embryonic gene expression patterns in the mouse using nonredundant sequence-based selection

      Sousa-Nunes, R., Rana, A. A., Kettleborough, R., Brickman, Joshua Mark, Clements, M., Forrest, A., Grimmond, S., Avner, P., Smith, J. C., Dunwoodie, S. L. & Beddington, R. S. P., Dec 2003, In: Genome Research. 13, 12, p. 2609-20 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    64. Published

      A homozygous mutation in HESX1 is associated with evolving hypopituitarism due to impaired repressor-corepressor interaction

      Carvalho, L. R., Woods, K. S., Mendonca, B. B., Marcal, N., Zamparini, A. L., Stifani, S., Brickman, Joshua Mark, Arnhold, I. J. P. & Dattani, M. T., Oct 2003, In: The Journal of Clinical Investigation. 112, 8, p. 1192-201 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    65. 2001
    66. Published

      Molecular effects of novel mutations in Hesx1/HESX1 associated with human pituitary disorders

      Brickman, Joshua Mark, Clements, M., Tyrell, R., McNay, D., Woods, K., Warner, J., Stewart, A., Beddington, R. S. & Dattani, M., Dec 2001, In: Development (Cambridge, England). 128, 24, p. 5189-99 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    ID: 35060713