Jens Lykkesfeldt

Jens Lykkesfeldt

Professor

Member of:

  • Lifepharm

ORCID: 0000-0002-6514-8407

Publication year:
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151 - 200 out of 270Page size: 50
  1. 2014
  2. Published

    Functional network analysis of obese and lean Göttingen minipigs elucidates changes in oxidative and inflammatory networks in obese pigs

    Boonen, H. C. M., Moesgaard, S. G., Birck, M. M., Christoffersen, B. Ø., Cirera, Susanna, Heegaard, P. M. H., Højbøge, T. R., Jensen, Lars Jørn, Mortensen, A., Olsen, Lisbeth Høier, Sheykhzade, Majid, Tang, J. & Lykkesfeldt, Jens, 2014, In: Pflügers ARchiv (European Journal of Physiology). 466, 12, p. 2167-2176 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    High-fat feeding increases hepatic vitamin C synthesis and its circulatory mobilization in mice

    Christensen, B. T., Hansen, Axel Kornerup & Lykkesfeldt, Jens, 2014, In: European Journal of Nutrition. 53, 6, p. 1441-1444 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    In vivo vitamin C deficiency in guinea pigs increases ascorbate transporters in liver but not kidney and brain

    Søgaard, D., Lindblad, M. M., Paidi, M. D., Andersen, S. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Nutrition Research. 34, 7, p. 639-645 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Melatonin does not affect oxidative/inflammatory biomarkers in a closed-chest porcine model of acute myocardial infarction

    Halladin, N. L., Busch, S. V. E., Jensen, S. E., Aarøe, J., Kjærgaard, B., Heegaard, P. M. H., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 2014, In: In Vivo. 28, p. 483-488 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Melatonin suppresses markers of inflammation and oxidative damage in a human daytime endotoxemia model

    Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 2014, In: Journal of Critical Care. 29, 1, p. 184.e9-184.e13 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Non-terminal blood sampling techniques in Guinea pigs

    Birck, M. M., Tveden-Nyborg, Pernille, Lindblad, M. M. & Lykkesfeldt, Jens, 2014, In: Journal of Visualized Experiments. 92, e51982.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Prenatal vitamin C deficiency results in differential levels of oxidative stress during late gestation in foetal guinea pig brains

    Paidi, M. D., Schjoldager, J. G., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Redox Biology. 2, p. 361-367 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Pronounced inflammatory response to endotoxaemia during nighttime: a randomised cross-over trial

    Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, I., 2014, In: PloS one. 9, 1, 7 p., e87413.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The kidneys play an important role in the clearance of rFVIIa in rats

    Vestergaard, Bill, Appa, R. S., Lykkesfeldt, Jens & Agersø, H., 2014, In: Thrombosis Research. 133, 6, p. 1124-1129 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Vitamin C

    Lykkesfeldt, Jens, Michels, A. J. & Frei, B., 2014, In: Advances in Nutrition. 5, 1, p. 16-18 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. 2013
  13. Published

    Ampicillin-improved glucose tolerance in diet-induced obese C57BL/6NTac mice is age dependent

    Rune, Ida, Hansen, Camilla Hartmann Friis, Ellekilde, M., Nielsen, Dennis Sandris, Skovgaard, K., Rolin, B. C., Lykkesfeldt, Jens, Josefsen, K., Christensen, B. T., Kihl, Pernille & Hansen, Axel Kornerup, 2013, In: Experimental Diabetes Research. 2013, 13 p., 319321.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Circadian Variation in the Response to Experimental Endotoxemia and Modulatory Effects of Exogenous Melatonin

    Alamili, M., Klein, M., Lykkesfeldt, Jens, Rosenberg, J. & Gögenur, I., 2013, In: Chronobiology International. 30, 9, p. 1174-1180 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Does vitamin C deficiency increase lifestyle-associated vascular disease progression? evidence based on experimental and clinical studies

    Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Antioxidants & Redox Signaling. 19, 17, p. 2084-2104 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Guinea pig ascorbate status predicts tetrahydrobiopterin plasma concentration and oxidation ratio in vivo

    Mortensen, A., Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Nutrition Research. 33, 10, p. 859-867 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Increased systemic oxidatively generated DNA and RNA damage in schizophrenia

    Jørgensen, A., Brødbæk, K., Fink-Jensen, Anders, Knorr, U., Greisen Søndergaard, M., Henriksen, T., Weimann, A., Jepsen, P., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen & Jørgensen, Martin Balslev, 2013, In: Psychiatry Research. 209, 3, p. 417–423 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Kinetics of acid-induced degradation of tetra- and dihydrobiopterin in relation to their relevance as biomarkers of endothelial function

    Mortensen, A. & Lykkesfeldt, Jens, 2013, In: Biomarkers. 18, 1, p. 55-62 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Nephrectomized and hepatectomized animal models as tools in preclinical pharmacokinetics

    Vestergaard, Bill, Agersø, H. & Lykkesfeldt, Jens, 2013, In: Basic & Clinical Pharmacology & Toxicology Online. 113, 2, p. 75-86 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Prolonged effect of a new O-glycoPEGylated FVIII (N8-GP) in a murine saphenous vein bleeding model

    Pastoft, A. E., Ezban, M., Tranholm, M., Lykkesfeldt, Jens & Lauritzen, B., 2013, In: Haemophilia Online. 19, 6, p. 913-919 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Prolonged maternal vitamin C deficiency overrides preferential fetal ascorbate transport but does not influence perinatal survival in guinea pigs

    Schjoldager, J. G., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: British Journal of Nutrition. 110, 9, p. 1573-1579 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Regulation of vitamin C homeostasis during deficiency

    Lindblad, M. M., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Nutrients. 5, 8, p. 2860-2879 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Translational aspects of rectal evoked potentials: a comparative study in rats and humans

    Nissen, T. D., Brock, C., Graversen, C., J. Coen, S., Hultin, L., Aziz, Q., Lykkesfeldt, Jens & Drewes, A. M., 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 305, p. G119-G128 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Whey protein reduces early life weight gain in mice fed a high-fat diet

    Christensen, B. T., Hellgren, L., Lykkesfeldt, Jens, Sejrsen, K., Jeamet, A., Rune, Ida, Ellekilde, M., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2013, In: PLOS ONE. 8, 8, 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. 2012
  26. Published

    A sensitive venous bleeding model in haemophilia A mice: effects of two recombinant FVIII products (N8 and Advate®)

    Pastoft, A. E., Lykkesfeldt, Jens, Ezban, M., Tranholm, M., Whinna, H. C. & Lauritzen, B., 2012, In: Haemophilia. 18, 5, p. 782-788 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Ascorbate and dehydroascorbic acid as biomarkers of oxidative stress: validity of clinical data depends on vacutainer system used

    Lykkesfeldt, Jens, 2012, In: Nutrition Research. 32, 1, p. 66-69 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Ascorbate status modulates reticuloendothelial iron stores and response to deferasirox iron chelation in ascorbate-deficient rats

    Brewer, C., Otto-Duessel, M., Lykkesfeldt, Jens, Nick, H. & Wood, J. C., 2012, In: Experimental Hematology. 40, 10, p. 820-827 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Chronic vitamin C deficiency does not accelerate oxidative stress in ageing brains of guinea pigs

    Tveden-Nyborg, Pernille, Andersen, S. H., Miyashita, N., Moos, T., Poulsen, Henrik Enghusen & Lykkesfeldt, Jens, 2012, In: Basic & Clinical Pharmacology & Toxicology Online. 110, 6, p. 524-529 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Maternal vitamin C deficiency during pregnancy persistently impairs hippocampal neurogenesis in offspring of guinea pigs

    Tveden-Nyborg, Pernille, Vogt, L., Schjoldager, J. G., Jeannet, N., Andersen, S. H., Paidi, M. D., Christen, S. & Lykkesfeldt, Jens, 2012, In: P L o S One. 7, 10, 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Oxidative stress response after laparoscopic versus conventional sigmoid resection: a randomized, double-blind clinical trial

    Madsen, M. T., Kücükakin, B., Lykkesfeldt, Jens, Rosenberg, J. & Gögenur, I., 2012, In: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques. 22, 3, p. 215-219 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Poor antioxidant status exacerbates oxidative stress and inflammatory response to Pseudomonas aeruginosa lung infection in Guinea Pigs

    Jensen, Peter Østrup, Lykkesfeldt, Jens, Bjarnsholt, Thomas, Hougen, H. P., Høiby, Niels & Ciofu, Oana, 2012, In: Basic & Clinical Pharmacology & Toxicology. 110, 4, p. 353-358 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Role of vitamin C and E supplementation on IL-6 in response to training

    Yfanti, C., Fischer, C. P., Nielsen, S., Åkerström, T., Nielsen, A. R., Veskoukis, A. S., Kouretas, D., Lykkesfeldt, Jens, Pilegaard, Henriette & Pedersen, Bente Klarlund, 2012, In: Journal of Applied Physiology. 112, 6, p. 990-1000 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Vitamin C and its role in brain development and cognition

    Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2012, Nutrition and mental performance: a develomental perspective. Riby, L., Smith, M. & Foster, J. (eds.). Palgrave Macmillan, p. 29-52 24 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  35. Published

    What is the optimum intake of vitamin C in humans?

    Frei, B., Birlouez-Aragon, I. & Lykkesfeldt, Jens, 2012, In: Critical Reviews in Food Science and Nutrition. 52, 9, p. 815-829 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. 2011
  37. Published

    The effect of altered gut flora on glucose intolerance in C57BL/6NTac mice

    Rune, Ida, Nielsen, Dennis Sandris, Hansen, Axel Kornerup, Ellekilde, M., Lykkesfeldt, Jens, Hansen, Camilla Hartmann Friis & Rolin, B., Nov 2011. 1 p.

    Research output: Contribution to conference › Poster › Research

  38. Published

    Animal models in pharmacology and toxicology

    Meyer, O. A., Svendsen, O. & Lykkesfeldt, Jens, 2011, Handbook of laboratory animal science: volume II: Animal models. Hau, J. & J. Schapiro, S. (eds.). 3. ed. ed. CRC Press, Vol. 2. p. 149-184 36 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  39. Published

    Effect of antioxidant supplementation on insulin sensitivity in response to endurance exercise training

    Yfanti, C., Nielsen, A. R., Åkerström, T., Nielsen, S., Rose, A. J., Richter, Erik A., Lykkesfeldt, Jens, Fischer, C. P. & Pedersen, Bente Klarlund, 2011, In: American Journal of Physiology: Endocrinology and Metabolism. 300, 5, p. E761-E770 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Effect of vitamin C and iron chelation on diesel exhaust particle and carbon black induced oxidative damage and cell adhesion molecule expression in human endothelial cells

    Frikke-Schmidt, H. R., Roursgaard, Martin, Lykkesfeldt, Jens, Loft, Steffen, Nøjgaard, J. K. & Møller, Peter, 2011, In: Toxicology Letters. 203, 3, p. 181-189 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Fluctuating hyperglycaemia increases oxidative stress response in lean rats compared to sustained hyperglycaemia despite lower glycaemic exposure

    Rakipovski, G., Raun, K. & Lykkesfeldt, Jens, 2011, In: Diabetes and Vascular Disease Research. 8, 4, p. 295-298 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    High dietary fat and cholesterol exacerbates chronic vitamin C deficiency in guinea pigs

    Frikke-Schmidt, H. R., Tveden-Nyborg, Pernille, Birck, M. M. & Lykkesfeldt, Jens, 2011, In: British Journal of Nutrition. 105, 1, p. 54-61 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Reply to Hemilä by Lykkesfeldt and Poulsen

    Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2011, In: British Journal of Nutrition. 105, 3, p. 488 1 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  44. Published

    Storage-induced increase in biomarkers of oxidative stress and inflammation in red blood cell components

    Kücükakin, B., Kocak, V., Lykkesfeldt, Jens, Nielsen, H. J., Magnussen, K., Rosenberg, Jacob & Gögenür, I., 2011, In: Scandinavian Journal of Clinical & Laboratory Investigation. 71, 4, p. 299-303 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    The effect of altered gut flora on glucose intolerance in C57BL/6NTac mice

    Rune, Ida, Ellekilde, M., Hansen, Camilla Hartmann Friis, Nielsen, Dennis Sandris, Rolin, B. C., Lykkesfeldt, Jens & Hansen, Axel Kornerup, 2011. 1 p.

    Research output: Contribution to conference › Poster › Research

  46. Published

    Vitamin C in human nutrition

    Frikke-Schmidt, H. R., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2011, Vitamins in the prevention of human diseases. Herrmann, W. & Obeid, R. (eds.). De Gruyter, p. 323-362 40 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  47. 2010
  48. Published

    Antioxidant supplementation does not alter endurance training adaptation

    Yfanti, C., Åkerström, T., Nielsen, S., Nielsen, A. R., Mounier, R., Mortensen, Ole Hartvig, Lykkesfeldt, Jens, Rose, A. J., Fischer, C. P. & Pedersen, Bente Klarlund, 1 Jul 2010, In: Medicine and Science in Sports and Exercise. 42, 7, p. 1388-95 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Is vitamin C supplementation beneficial? lessons learned from randomised controlled trials

    Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2010, In: British Journal of Nutrition. 103, 9, p. 1251-1259 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Keeping the intracellular vitamin C at a physiologically relevant level in endothelial cell culture

    Frikke-Schmidt, H. R. & Lykkesfeldt, Jens, 2010, In: Analytical Biochemistry. 397, 1, p. 135-137 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    No effect of melatonin on oxidative stress after laparoscopic cholecystectomy: a randomized placebo-controlled trial

    Kücükakin, B., Klein, M., Lykkesfeldt, Jens, Reiter, R. J., Rosenberg, J. & Gögenür, I., 2010, In: Acta Anaesthesiologica Scandinavica. 54, 9, p. 1121-1127 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    No effect of melatonin to modify surgical-stress response after major vascular surgery: a randomised placebo-controlled trial

    Kücükakin, B., Wilhelmsen, M., Lykkesfeldt, Jens, Reiter, R. J., Rosenberg, J. & Gögenur, I., 2010, In: European Journal of Vascular and Endovascular Surgery. 40, 4, p. 461-467 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Obese Prone Rats on high- and low-fat diets gain weight equally

    Christensen, B. T., Hellgren, L., Sejrsen, K., Lykkesfeldt, Jens & Hansen, Axel Kornerup, 2010.

    Research output: Contribution to conference › Poster › Research

  54. 2009
  55. Published

    C-Vitamin mod åreforkalkning

    Frikke-Schmidt, H. R. & Lykkesfeldt, Jens, 2009, In: Aktuel Naturvidenskab. 3, p. 26-29 4 p.

    Research output: Contribution to journal › Journal article › Communication

  56. Published

    Does vitamin C deficiency result in impaired brain development in infants?

    Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2009, In: Redox Report. 14, 1, p. 2-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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