Jens Lykkesfeldt

Jens Lykkesfeldt

Professor

Member of:

  • Lifepharm

ORCID: 0000-0002-6514-8407

Publication year:
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101 - 150 out of 276Page size: 50
  1. 2013
  2. Published

    Circadian Variation in the Response to Experimental Endotoxemia and Modulatory Effects of Exogenous Melatonin

    Alamili, M., Klein, M., Lykkesfeldt, Jens, Rosenberg, J. & Gögenur, I., 2013, In: Chronobiology International. 30, 9, p. 1174-1180 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Does vitamin C deficiency increase lifestyle-associated vascular disease progression? evidence based on experimental and clinical studies

    Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Antioxidants & Redox Signaling. 19, 17, p. 2084-2104 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Guinea pig ascorbate status predicts tetrahydrobiopterin plasma concentration and oxidation ratio in vivo

    Mortensen, A., Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Nutrition Research. 33, 10, p. 859-867 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Increased systemic oxidatively generated DNA and RNA damage in schizophrenia

    Jørgensen, A., Brødbæk, K., Fink-Jensen, Anders, Knorr, U., Greisen Søndergaard, M., Henriksen, T., Weimann, A., Jepsen, P., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen & Jørgensen, Martin Balslev, 2013, In: Psychiatry Research. 209, 3, p. 417–423 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Kinetics of acid-induced degradation of tetra- and dihydrobiopterin in relation to their relevance as biomarkers of endothelial function

    Mortensen, A. & Lykkesfeldt, Jens, 2013, In: Biomarkers. 18, 1, p. 55-62 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Nephrectomized and hepatectomized animal models as tools in preclinical pharmacokinetics

    Vestergaard, Bill, Agersø, H. & Lykkesfeldt, Jens, 2013, In: Basic & Clinical Pharmacology & Toxicology Online. 113, 2, p. 75-86 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Prolonged effect of a new O-glycoPEGylated FVIII (N8-GP) in a murine saphenous vein bleeding model

    Pastoft, A. E., Ezban, M., Tranholm, M., Lykkesfeldt, Jens & Lauritzen, B., 2013, In: Haemophilia Online. 19, 6, p. 913-919 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Prolonged maternal vitamin C deficiency overrides preferential fetal ascorbate transport but does not influence perinatal survival in guinea pigs

    Schjoldager, J. G., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: British Journal of Nutrition. 110, 9, p. 1573-1579 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Regulation of vitamin C homeostasis during deficiency

    Lindblad, M. M., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Nutrients. 5, 8, p. 2860-2879 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Translational aspects of rectal evoked potentials: a comparative study in rats and humans

    Nissen, T. D., Brock, C., Graversen, C., J. Coen, S., Hultin, L., Aziz, Q., Lykkesfeldt, Jens & Drewes, A. M., 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 305, p. G119-G128 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Whey protein reduces early life weight gain in mice fed a high-fat diet

    Christensen, B. T., Hellgren, L., Lykkesfeldt, Jens, Sejrsen, K., Jeamet, A., Rune, Ida, Ellekilde, M., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2013, In: PLOS ONE. 8, 8, 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. 2014
  14. Published

    Antioxidant supplementation for lung disease in cystic fibrosis

    Ciofu, Oana & Lykkesfeldt, Jens, 2014, In: The Cochrane library. 2014, 8, 87 p., CD007020.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats

    Knudsen, K. B., Northeved, H., Gjetting, T., Permin, A., Andresen, T. L., Wegener, K. M., Rye Lam, H. & Lykkesfeldt, Jens, 2014, In: Journal of Nanoparticle Research. 16, 1, 11 p., 2221.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Biopterin status in dogs with myxomatous mitral valve disease is associated with disease severity and cardiovascular risk factors

    Reimann, Maria Josefine, Häggström, J., Mortensen, A., Lykkesfeldt, Jens, Møller, J. E., Falk, B. T. & Olsen, Lisbeth Høier, 2014, In: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. 28, 5, p. 1520-1526 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Chronic vitamin C deficiency promotes redox imbalance in the brain but does not alter sodium-dependent vitamin C transporter 2 expression

    Paidi, M. D., Schjoldager, J. G., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Nutrients. 6, 5, p. 1809-1822 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Differential toxicological response to positively and negatively charged nanoparticles in the rat brain

    Knudsen, K. B., Northeved, H., Ek, P. K., Permin, A., Andresen, T. L., Larsen, S., Wegener, K. M., Lam, H. R. & Lykkesfeldt, Jens, 2014, In: Nanotoxicology. 8, 7, p. 764-774 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Does vitamin C deficiency affect cognitive development and function?

    Hansen, S. N., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2014, In: Nutrients. 6, 9, p. 3818-3846 29 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Does vitamin C deficiency promote fatty liver disease development?

    Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2014, In: Nutrients. 6, 12, p. 5473-5499 27 p.

    Research output: Contribution to journal › Review › Research › peer-review

  21. Published

    Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies

    Mortensen, A. & Lykkesfeldt, Jens, 2014, In: Nitric Oxide: Biology and Chemistry. 36, p. 51-57 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  22. Published

    Effect of insulin-induced hypoglycaemia on the central nervous system: evidence from experimental studies

    Jensen, Vivi Flou Hjorth, Bøgh, I. B. & Lykkesfeldt, Jens, 2014, In: Journal of Neuroendocrinology. 26, 3, p. 123-150 28 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Effect of insulin-induced hypoglycaemia on the peripheral nervous system: focus on adaptive mechanisms, pathogenesis and histopathological changes

    Jensen, Vivi Flou Hjorth, Mølck, A., Bøgh, I. B. & Lykkesfeldt, Jens, 2014, In: Journal of Neuroendocrinology. 26, 8, p. 482-496 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Effect of melatonin on human nighttime endotoxaemia: randomized, double-blinded, cross-over study

    Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 2014, In: In Vivo. 28, 6, p. 1057-1063 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Functional network analysis of obese and lean Göttingen minipigs elucidates changes in oxidative and inflammatory networks in obese pigs

    Boonen, H. C. M., Moesgaard, S. G., Birck, M. M., Christoffersen, B. Ø., Cirera, Susanna, Heegaard, P. M. H., Højbøge, T. R., Jensen, Lars Jørn, Mortensen, A., Olsen, Lisbeth Høier, Sheykhzade, Majid, Tang, J. & Lykkesfeldt, Jens, 2014, In: Pflügers ARchiv (European Journal of Physiology). 466, 12, p. 2167-2176 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    High-fat feeding increases hepatic vitamin C synthesis and its circulatory mobilization in mice

    Christensen, B. T., Hansen, Axel Kornerup & Lykkesfeldt, Jens, 2014, In: European Journal of Nutrition. 53, 6, p. 1441-1444 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    In vivo vitamin C deficiency in guinea pigs increases ascorbate transporters in liver but not kidney and brain

    Søgaard, D., Lindblad, M. M., Paidi, M. D., Andersen, S. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Nutrition Research. 34, 7, p. 639-645 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Melatonin does not affect oxidative/inflammatory biomarkers in a closed-chest porcine model of acute myocardial infarction

    Halladin, N. L., Busch, S. V. E., Jensen, S. E., Aarøe, J., Kjærgaard, B., Heegaard, P. M. H., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 2014, In: In Vivo. 28, p. 483-488 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Melatonin suppresses markers of inflammation and oxidative damage in a human daytime endotoxemia model

    Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 2014, In: Journal of Critical Care. 29, 1, p. 184.e9-184.e13 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Non-terminal blood sampling techniques in Guinea pigs

    Birck, M. M., Tveden-Nyborg, Pernille, Lindblad, M. M. & Lykkesfeldt, Jens, 2014, In: Journal of Visualized Experiments. 92, e51982.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Prenatal vitamin C deficiency results in differential levels of oxidative stress during late gestation in foetal guinea pig brains

    Paidi, M. D., Schjoldager, J. G., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Redox Biology. 2, p. 361-367 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Pronounced inflammatory response to endotoxaemia during nighttime: a randomised cross-over trial

    Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, I., 2014, In: PloS one. 9, 1, 7 p., e87413.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    The kidneys play an important role in the clearance of rFVIIa in rats

    Vestergaard, Bill, Appa, R. S., Lykkesfeldt, Jens & Agersø, H., 2014, In: Thrombosis Research. 133, 6, p. 1124-1129 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Vitamin C

    Lykkesfeldt, Jens, Michels, A. J. & Frei, B., 2014, In: Advances in Nutrition. 5, 1, p. 16-18 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Positive charge, negative effect: the impact of cationic nanoparticles in the brain

    Møller, Peter & Lykkesfeldt, Jens, Jul 2014, In: Nanomedicine. 9, 10, p. 1441-3 3 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  36. 2015
  37. Published

    Asymmetric dimethylarginine in somatically healthy schizophrenia patients treated with atypical antipsychotics: a case-control study

    Jørgensen, Anders, Knorr, Ulla Benedichte Søsted, Soendergaard, M. G., Lykkesfeldt, Jens, Fink-Jensen, Anders, Poulsen, Henrik Enghusen, Jørgensen, Martin Balslev, Olsen, N. V. & Staalsø, J. M., 2015, In: B M C Psychiatry. 15, 8 p., 67.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Controlled exposure to particulate matter from urban street air is associated with decreased vasodilation and heart rate variability in overweight and older adults

    Hemmingsen, J. G., Rissler, J., Lykkesfeldt, Jens, Sallsten, G., Kristiansen, J., Møller, Peter & Loft, Steffen, 2015, In: Particle and Fibre Toxicology. 12, 10 p., 6.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Distribution of vitamin C is tissue specific with early saturation of the brain and adrenal glands following differential oral dose regimens in guinea pigs

    Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2015, In: British Journal of Nutrition. 113, 10, p. 1539-1549 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Elimination of ascorbic acid after high-dose infusion in prostate cancer patients: a pharmacokinetic evaluation

    Nielsen, Torben Kjær, Højgaard, M., Andersen, J. T. T., Poulsen, Henrik Enghusen, Lykkesfeldt, Jens & Mikines, K. J., 2015, In: Basic & Clinical Pharmacology & Toxicology. 116, 4, p. 343-348 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Göttingen minipig model of diet-induced atherosclerosis: influence of mild streptozotocin-induced diabetes on lesion severity and markers of inflammation evaluated in obese, obese and diabetic, and lean control animals

    Ludvigsen, Trine Pagh, Kirk, R. K., Christoffersen, B. Ø., Pedersen, H. D., Martinussen, Torben, Kildegaard, J., Heegaard, P. M. H., Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2015, In: Journal of Translational Medicine. 13, 12 p., 312.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Maternal vitamin C deficiency during pregnancy results in transient fetal and placental growth retardation in guinea pigs: [Plus] erratum

    Schjoldager, J. G., Paidi, M. D., Lindblad, M. M., Birck, M. M., Kjærgaard, A. B., Dantzer, V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2015, In: European Journal of Nutrition. 54, 4, p. 667-676 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    In vivo toxicity of cationic micelles and liposomes

    Knudsen, K. B., Northeved, H., Kumar Ek, P., Permin, A., Gjetting, T., Andresen, T. L., Larsen, S., Wegener, K. M., Lykkesfeldt, Jens, Jantzen, K., Loft, Steffen, Møller, Peter & Roursgaard, Martin, 25 Feb 2015, In: Nanomedicine: Nanotechnology, Biology and Medicine. 11, 2, p. 467-477 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection: a pilot study

    Skov, M., Pressler, T., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen, Jensen, Peter Østrup, Johansen, Helle Krogh, Qvist, T., Kræmer, D., Høiby, Niels & Ciofu, Oana, Mar 2015, In: Journal of Cystic Fibrosis. 14, 2, p. 211-218 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Lower limb ischaemia and reperfusion injury in healthy volunteers measured by oxidative and inflammatory biomarkers

    Halladin, N. L., Busch, S. V. E., Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 10 Apr 2015, In: Perfusion. 30, 1, p. 64-70 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Chronic dyslipidemia induces fatty liver disease in Guinea pigs

    Tveden-Nyborg, Pernille, Birck, M. M., Ipsen, David Højland & Lykkesfeldt, Jens, Jul 2015, In: Atherosclerosis. 241, 1, p. e119-e120 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  47. Published

    Thick methacrylate sections devoid of lost caps simplify stereological quantifications based on the optical fractionator design

    Andersen, S. H., Lykkesfeldt, Jens & Larsen, J. O., 15 Sep 2015, In: Anatomical Record. 298, 12, p. 2141-2150 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. 2016
  49. Published

    L-dehydroascorbic acid can substitute L-ascorbic acid as dietary vitamin C source in guinea pigs

    Frikke-Schmidt, H. R., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2016, In: Redox Biology. 7, p. 8-13 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Does Glucagon-like Peptide-1 Ameliorate Oxidative Stress in Diabetes? Evidence Based on Experimental and Clinical Studies

    Petersen, Karen Ekkelund, Rakipovski, G., Raun, K. & Lykkesfeldt, Jens, 2016, In: Current Diabetes Reviews. 12, 4, p. 331-358 28 p.

    Research output: Contribution to journal › Review › Research › peer-review

  51. Published

    High-fat but not sucrose intake is essential for induction of dyslipidemia and non-alcoholic steatohepatitis in guinea pigs

    Ipsen, David Højland, Tveden-Nyborg, Pernille, Rolin, B., Rakipovski, G., Beck, M., Mortensen, L. W., Færk, L., Heegaard, P. M. H., Møller, Peter & Lykkesfeldt, Jens, 2016, In: Nutrition & Metabolism. 13, p. 51

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Modulating the gut microbiota improves glucose tolerance, lipoprotein profile and atherosclerotic plaque development in ApoE-deficient mice

    Rune, Ida, Rolin, B., Larsen, C. S., Nielsen, Dennis Sandris, Kanter, J. E., Bornfeldt, K. E., Lykkesfeldt, Jens, Buschard, K., Kirk, R. K., Christoffersen, B., Fels, J. J., Josefsen, K., Kihl, Pernille & Hansen, Axel Kornerup, 2016, In: P L o S One. 11, 1, 16 p., e0146439.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Simvastatin and oxidative stress in humans: A randomized, double-blinded, placebo-controlled clinical trial

    Rasmussen, S. T., Andersen, Jon Thor Trærup, Nielsen, T. K., Cejvanovic, V., Petersen, K. M., Henriksen, T., Weimann, A., Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2016, In: Redox Biology. 9, p. 32-38

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Vitaminer til hjernen

    Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2016, In: Aktuel Naturvidenskab. 2016, 4, p. 8-11 4 p.

    Research output: Contribution to journal › Journal article › Research

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ID: 4231856