Jens Lykkesfeldt

Jens Lykkesfeldt

Professor

Member of:

  • Lifepharm

ORCID: 0000-0002-6514-8407

Publication year:
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1 - 100 out of 276Page size: 100
  1. 1991
  2. Published

    2-Nitro-3-(p-hydroxyphenyl)propionate and aci-1-nitro-2-(p-hydroxyphenyl)ethane, two intermediates in the biosynthesis of the cyanogenic glucoside dhurrin in Sorghum bicolor (L.) Moench

    Halkier, Barbara Ann, Lykkesfeldt, Jens & Møller, Birger Lindberg, 1 Jan 1991, In: Proceedings of the National Academy of Sciences of the United States of America. 88, 2, p. 487-491 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 1993
  4. Published

    Synthesis of benzylglucosinolate in Tropaeolum majus L. Isothiocyanates as potent enzyme inhibitors

    Lykkesfeldt, Jens & Møller, Birger Lindberg, 1 Jan 1993, In: Plant Physiology. 102, 2, p. 609-613 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Nitrosamindannende håndkøbspraeparater?

    Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 13 Dec 1993, In: Ugeskrift for Laeger. 155, 50, p. 4106-4107 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  6. 1994
  7. Published

    Simultaneous determination of urinary free cortisol and 6*Gb-hydroxycortisol by high-performance liquid chromatography to measure human CYP3A activity

    Lykkesfeldt, Jens, Loft, Steffen & Poulsen, Henrik Enghusen, 1994, In: Journal of Chromatography B: Biomedical Sciences and Applications. 660, p. 23-29

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Simultaneous determination of urinary free cortisol and 6β-hydroxycortisol by high-performance liquid chromatography to measure human CYP3A activity

    Lykkesfeldt, Jens, Loft, Steffen & Poulsen, Henrik Enghusen, 3 Oct 1994, In: Journal of Chromatography B: Biomedical Sciences and Applications. 660, 1, p. 23-29 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. 1995
  10. Published

    Determination of Ascorbic Acid and Dehydroascorbic Acid in Plasma by High-Performance Liquid Chromatography with Coulometric Detection - Are They Reliable Biomarkers of Oxidative Stress?

    Lykkesfeldt, Jens, Loft, Steffen & Poulsen, Henrik Enghusen, 1995, In: Analytical Biochemistry. 229, p. 329-335

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Involvment of cytochrome P450 in Oxime production in glucosinolate biosynthesis as demonstrated by an in vitro microsomale enzyme system isolated from jasmonic acid-induced seedlings of Sinapis alba

    Du, L., Lykkesfeldt, Jens, Olsen, C. E. & Halkier, B. A., 1995, In: Proceedings of the National Academy of Science of the United States of America. 92, 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Selective serotonin reuptake inhibitors and theophylline metabolism in human liver microsomes: potent inhibition by fluvoxamine

    Rasmussen, B. B., Mäenpää, J., Pelkonen, O., Loft, Steffen, Poulsen, Henrik Enghusen, Lykkesfeldt, Jens & Brøsen, K., 1995, In: British Journal of Clinical Pharmacology. 39, p. 151-159

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Involvement of cytochrome P450 in oxime production in glucosinolate biosynthesis as demonstrated by an in vitro microsomal enzyme system isolated from jasmonic acid-induced seedlings of Sinapis alba L.

    Du, L., Lykkesfeldt, Jens, Olsen, C. E. & Halkier, Barbara Ann, 19 Dec 1995, In: Proceedings of the National Academy of Sciences of the United States of America. 92, 26, p. 12505-12509 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 1996
  15. Published

    Effect of smoking cessation on plasma ascorbic acid concentration

    Lykkesfeldt, Jens, Priemé, H., Loft, Steffen & Poulsen, Henrik Enghusen, 13 Jul 1996, In: B M J (Clinical Research Edition). 313, 7049, p. 91

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 1997
  17. Published

    Ascorbic acid and dehydroascorbic acid as biomarkers of oxidative stress caused by smoking, 1-3

    Lykkesfeldt, Jens, Loft, Steffen, Nielsen, J. B. & Poulsen, Henrik Enghusen, 1997, In: American Journal of Clinical Nutrition. 65, p. 959-963

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. 1998
  19. Published

    Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity

    Hagen, T. M., Ingersoll, R. T., Wehr, C. M., Lykkesfeldt, Jens, Vinarsky, V., Bartholomew, J. C., Song, M. & Ames, B. N., 1998, In: Proceedings of the National Academy of Science of the United States of America. 95, p. 9562-9566 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Age-associated decline in ascorbic acid concentration, recycling, and biosynthesis in rat hepatocytes: reversal with (R)-alfa-lipoic acid supplementation

    Lykkesfeldt, Jens, Hagen, T. M., Vinarsky, V. & Ames, B. N., 1998, In: The FASEB Journal. 12, p. 1183-1189 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Oxidative DNA damage in vivo: relationship to age, plasma antioxidants, drug metabolism, glutathione-S-transferase activity and urinary creatinine excretion

    Poulsen, H. E., Loft, S., Prieme, H., Vistisen, K., Lykkesfeldt, Jens, Nyyssonen, K. & Salonen, J. T., 1998, In: Free Radical Research. 29, p. 565-571 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Oxidative DNA damage in vivo: Relationship to age, plasma antioxidants, drug metabolism, glutathione-S-transferase activity and urinary creatinine excretion

    Poulsen, Henrik Enghusen, Loft, Steffen, Prieme, H., Vistisen, K. K., Lykkesfeldt, Jens, Nyyssonen, K. & Salonen, J. T., 1998, In: Free Radical Research. 29, p. 565-571

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Artemisinin induces omeprazole metabolism in human beings

    Svensson, U. S. H., Ashton, M., Hai, T. N., Bertilsson, L., Huong, D. X., Van Huong, N., Niêu, N. T., Sy, N. D., Lykkesfeldt, Jens & Công, L. D., 1 Aug 1998, In: Clinical Pharmacology and Therapeutics. 64, 2, p. 160-167 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Ascorbic acid recycling in rat hepatocytes as measurement of antioxidant capacity: Decline with age

    Lykkesfeldt, Jens & Ames, B. N., 3 Nov 1998, In: Methods in Enzymology. 299, p. 83-88 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. 1999
  26. Published

    (R)-alfa-lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate

    Hagen, T. M., Ingersoll, R. T., Lykkesfeldt, Jens, Liu, J., Wehr, C. M., Vinarsky, V., Bartholomew, J. C. & Ames, B. N., 1999, In: The FASEB Journal. 13, p. 411-4418 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Ascorbic acid recycling in rat hepatocytes as measurement of antioxidant capacity: decline with age

    Lykkesfeldt, Jens & Ames, B. N., 1999, In: Methods in Enzymology. 299, p. 83-88 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Ascorbic acid recycling in rat hepatocytes as measurement of antioxidant capacity: decline with age

    Lykkesfeldt, Jens & Ames, B. N., 1999, Oxidants and antioxidants part A. Packer, L. (ed.). San Diego: Academic Press, Vol. 299. p. 83-88 6 p. (Methods in Enzymology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  29. Published

    (R)-α-Lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate

    Hagen, T. M., Ingersoll, R. T., Lykkesfeldt, Jens, Liu, J., Wehr, C. M., Vinarsky, V., Bartholomew, J. C. & Ames, B. N., 16 Feb 1999, In: FASEB Journal. 13, 2, p. 411-418 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. 2000
  31. Published

    Ascorbate is depleted by smoking and repleted by moderate supplementation: a study in male smokers and nonsmokers with matched dietary antioxidant intakes

    Lykkesfeldt, Jens, Christen, S., Wallock, L. M., Chang, H. H., Jacob, R. A. & Ames, B. N., 2000, In: American Journal of Clinical Nutrition. 71, p. 530-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Biochemical markers as indicators of the efficiency of antibiotic treatment of Actinobacillus pleuropneumoniae infection in pigs

    Lauritsen, B., Lykkesfeldt, Jens, Angen, Ø. & Friis, C., 2000. 1 p.

    Research output: Contribution to conference › Paper › Research

  33. Published

    Determination of ascorbic acid and dehydroascorbic acid in biological samples by high-performance liquid chromatography using subtraction methods: reliable reduction with tris[2-carboxyethyl]phosphine hydrochloride

    Lykkesfeldt, Jens, 2000, In: Analytical Biochemistry. 282, p. 89-93 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Morphine concentration in plasma andcerebrospinal fluid in the anaesthetised pig after a single intravenous administration

    Lykkegaard, K., Lykkesfeldt, Jens & Svendsen, O., 2000. 1 p.

    Research output: Contribution to conference › Paper › Research

  35. Published

    On the possible connection between vitamin C, cardiovirus and guinea pig lameness

    Clausen, F. B., Lykkesfeldt, Jens & Hansen, Axel Kornerup, 2000, Ikke angivet. Laboratory Animals Ltd, p. 101-104 4 p.

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research

  36. 2001
  37. Published

    Determination of malondialdehyde as dithiobarbituric acid adduct in biological samples by HPLC with fluorescence detection: comparison with ultraviolet-visible spectrophotometry

    Lykkesfeldt, Jens, 2001, In: Clinical Chemistry. 47, 9, p. 1725-1727 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Determination of the disappearance rate of iodine-125 labelled oils from the injection site after intramuscular and subcutaneous administration to pigs

    Weng Larsen, S., Reinvar, E., Svendsen, O., Lykkesfeldt, Jens, Friis, G. J. & Larsen, C., 2001, In: Internation Journal of Pharmaceutics. 230, p. 67-75 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Oxidative stress in brain during experimental bacterial meningitis: differential effects of alpha-phenyl-tert-butyl nitrone and N-acetylcysteine treatment

    Christen, S., Schaper, M., Lykkesfeldt, Jens, Siegenthaler, C., Bifrare, Y., Banic, S. O., Leib, S. L. & Täuber, M. G., 2001, In: Free Radical Biology & Medicine. 31, 6, p. 754-762 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. 2002
  41. Published

    Biomarkers in evaluation of antibiotic treatment: an experimental model of porcine Actinobacillus pleuropneumoniae infection

    Lauritzen, B., Lykkesfeldt, Jens, Angen, Ø., Nielsen, Jens Peter & Friis, C., 2002.

    Research output: Contribution to conference › Paper › Research

  42. Published

    Cerebral vasculature is the major target of oxidative protein alterations in bacterial meningitis

    Schaper, M., Gergely, S., Lykkesfeldt, Jens, Zbären, J., Leib, S. L., Täuber, M. G. & Christen, S., 2002, In: Journal of Neuropathology and Experimental Neurology. 61, 7, p. 605-613 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Distribution of enrofloxacin in intestinal tissue and contents of healthy pigs after oral and intramuscular administrations

    Wiuff, C., Lykkesfeldt, Jens, Aarestrup, F. M. & Svendsen, O., 2002, In: Journal of Veterinary Pharmacology and Therapeutics. 25, 5, p. 335-342 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Evaluation of a single dose and a split-dose regimen of danofloxacin against Actinobacillus pleuropneumoniae infection in pigs

    Lauritzen, B., Lykkesfeldt, Jens & Friis, C., 2002.

    Research output: Contribution to conference › Paper › Research

  45. Published

    Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress

    Hagen, T. M., Liu, J., Lykkesfeldt, Jens, Wehr, C. M., Ingersoll, R. T., Vinarsky, V., Bartholomew, J. C. & Ames, B. N., 2002, In: Proceedings of the National Academy of Science of the United States of America. 99, 4, p. 1870-1875 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Gamma-tocopherol supplementation inhibits protein nitration and ascorbate oxidation in rats with inflammation

    Jiang, Q., Lykkesfeldt, Jens, Shigenaga, M. K., Shigeno, E. T., Christen, S. & Ames, B. N., 2002, In: Free Radical Biology & Medicine. 33, 11, p. 1534-1542 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Increased oxidative damage in vitamin C deficiency is accompanied by induction of ascorbic acid recycling capacity in young but not mature guinea pigs

    Lykkesfeldt, Jens, 2002, In: Free Radical Research. 36, 5, p. 567-574 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Measurement of ascorbic acid and dehydroascorbic acid in biological samples

    Lykkesfeldt, Jens, 2002, Current protocols in toxicology. Maines, M., Costa, L. G., Hodson, E., Reed, D. J. & Sipes, I. G. (eds.). New York: Wiley, p. 7.6.1-7.6.15 15 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  49. 2003
  50. Published

    Ascorbic acid recycling in human erythrocytes is induced by smoking in vivo

    Lykkesfeldt, Jens, Viscovich, M. & Poulsen, H. E., 2003, In: Free Radical Biology & Medicine. 11, 11, p. 1439-1447 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Effect of smoking on erythorbic acid pharmacokinetics

    Lykkesfeldt, Jens, Bolbjerg, M. L. & Poulsen, H. E., 2003, In: British Journal of Nutrition. 89, 5, p. 667-671 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Evaluation of a single dose versus a divided dose regimen of danofloxacin in treatment of Actinobacillus pleuropneumoniae infection in pigs

    Lauritzen, B., Lykkesfeldt, Jens & Friis, C., 2003, In: Research in Veterinary Science. 74, 3, p. 271-277 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Putative biomarkers for evaluating antibiotic treatment: an experimental model of porcine Actinobacillus pleuropneumoniae infection

    Lauritzen, B., Lykkesfeldt, Jens, Skaanild, M. T., Angen, Ø., Nielsen, Jens Peter & Friis, C., 2003, In: Research in Veterinary Science. 74, 3, p. 261-270 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    The effects of oral and intramuscular administration and dose escalation of enrofloxacin on the selection of quinolone resistance among Salmonella and coliforms in pigs

    Wiuff, C., Lykkesfeldt, Jens, Svendsen, O. & Aarestrup, F. M., 2003, In: Research in Veterinary Science. 75, 3, p. 185-193 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. 2004
  56. Published

    Clindamycin is neuroprotective in experimental Streptococcus pneumoniae meningitis compared with ceftriaxone

    Böttcher, T., Ren, H., Goiny, M., Gerber, J., Lykkesfeldt, Jens, Kuhnt, U., Lotz, M., Bunkowski, S., Werner, C., Schau, I., Spreer, A., Christen, S. & Nau, R., 2004, In: Journal of Neurochemistry. 91, 6, p. 1450-1460 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Long-term high copper intake: effects on indexes of copper status, antioxidant status, and immune function in young men 1-3

    Turnlund, J. R., Jacob, R. A., Keen, C. L., Strain, J. J., Kelly, D. S., Domek, J. M., Keyes, W. R., Ensunsa, J. L., Lykkesfeldt, Jens & Coulter, J., 2004, In: American Journal of Clinical Nutrition. 79, 6, p. 1037-1044 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Optimized treatment regimens for enrofloxacin in pigs limits selection for resistance in salmonella and coliforms

    Wiuff, C., Lykkesfeldt, Jens, Aarestrup, F. M. & Svendsen, O., 2004. 1 p.

    Research output: Contribution to conference › Paper › Research

  59. Published

    Pharmacokinetics of amoxicillin after oral administration in recently weaned piglets with experimentally induced Escherichia coli subtype O149:F4 diarrhea

    Jensen, G. M., Lykkesfeldt, Jens, Frydendahl, K., Møller, K. & Svendsen, O., 2004, In: American Journal of Veterinary Research. 65, p. 992-995 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Plasma malondialdehyde is induced by smoking: a study with balanced antioxidant profiles

    Lykkesfeldt, Jens, Viscovich, M. & Poulsen, H. E., 2004, In: British Journal of Nutrition. 92, 2, p. 203-206 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Vitamin C and oxidative damage to DNA: chapter 11

    Poulsen, Henrik Enghusen, Møller, P., Lykkesfeldt, Jens, Weimann, A. & Loft, S., 2004, Vitamin C. Asard, H., May, J. M. & Smirnoff, N. (eds.). Oxford: BIOS Scientific Publishers, p. 189-202 14 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  62. Published

    Vitamin C pharmacokinetics of plain and slow release formulations in smokers

    Viscovich, M., Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2004, In: Clinical Nutrition. 23, 5, p. 1043-1050 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Vitamin C supplementation decreases oxidative DNA damage in mononuclear bood cells of smokers

    Møller, P., Viscovich, M., Lykkesfeldt, Jens, Loft, S., Jensen, A. & Poulsen, H. E., 2004, In: European Journal of Nutrition. 43, p. 267-274 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. 2005
  65. Published

    Age-dependent change in Vitamin C status: a phenomenon of matruration rather than of ageing

    Lykkesfeldt, Jens & Moos, T., 2005, In: Mechanisms of Ageing and Development. 126, 8, p. 892-898 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Effects of heparin-binding protein (CAP37/azurocidin) in a porcine model of Actinobacillus pleuropneumoniae-induced pneumonia

    Lauritzen, B., Lykkesfeldt, Jens, Djurup, R., Flodgaard, H. & Svendsen, O., 2005, In: Pharmacological Research. 51, 6, p. 509-514 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Electroencephalographic changes after pediatric cardiac surgery with cardiopulmonary bypass: is slow wave activity unfavorable?

    Schmitt, B., Finckh, B., Christen, S., Lykkesfeldt, Jens, Schmid, E. R., Bauersfeld, U., Critelli, H., Hajnal, B. L., Gessler, P. & Molinari, L., 2005, In: Pediatric Research. 58, 4, p. 771-778 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Evaluation of a single dose versus a divided dose regimen of amoxycillin in treatment of Actinobacillus pleuropneumoniae infection in pigs

    Lauritzen, B., Lykkesfeldt, Jens & Friis, C., 2005, In: Research in Veterinary Science. 79, 1, p. 61-67 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Oxidative stress precedes peak systemic inflammatory response in pediatric patients undergoing cardiopulmonary bypass operation

    Christen, S., Finckh, B., Lykkesfeldt, Jens, Gessler, P., Frese-Schaper, M., Nielsen, P., Schmid, E. R. & Schmitt, B., 2005, In: Free Radical Biology & Medicine. 38, 10, p. 1323-1332 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Vitamin C: as biomarker and treatment of oxidative stress caused by smoking : methodological and clinical studies

    Lykkesfeldt, Jens, 2005, Copenhagen: Center for Skov, Landskab og Planlægning/Københavns Universitet. 59 p.

    Research output: Book/Report › Doctoral thesis › Research

  71. 2006
  72. Published

    Pharmacokinetics of amoxicillin administered in drinking water to recently weaned 3- to 4-week-old pigs with diarrhea experimentally induced by Escherichia coli O149:F4

    Jensen, G. M., Lykkesfeldt, Jens, Frydendahl, K., Møller, K. & Svendsen, O., 2006, In: American Journal of Veterinary Research. 67, 4, p. 648-653 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Smoking depletes vitamin C: should smokers be recommended to take supplements?

    Lykkesfeldt, Jens, 2006, Cigarette smoke and oxidative stress. Halliwell, B. B. & Poulsen, H. E. (eds.). Berlin: Kluwer Academic Publishers, p. 236-258 23 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  74. 2007
  75. Published

    Ascorbate and dehydroascorbic acid as reliable biomarkers of oxidative stress: analytical reproducibility and long-term stability of plasma samples subjected to acidic deproteinization

    Lykkesfeldt, Jens, 2007, In: Cancer Epidemiology, Biomarkers & Prevention. 16, 11, p. 2513-2516 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Malondialdehyde as biomarker of oxidative damage to lipids caused by smoking: invited critical review

    Lykkesfeldt, Jens, 2007, In: Clinica Chimica Acta. 380, 1-2, p. 50-58 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Oxidants and antioxidants in disease: oxidative stress in farm animals

    Lykkesfeldt, Jens & Svendsen, O., 2007, In: Veterinary Journal. 173, 3, p. 502-511 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Oxidative stress and damage in liver, but not in brain, of Fischer 344 rats subjected to dietary iron supplementation with lipid-soluble[(3,5,5-Trimethylhexanoyl)ferrocene]

    Lykkesfeldt, Jens, Morgan, E., Christen, S., Skovgaard, L. T. & Moos, T., 2007, In: Journal of Biochemical and Molecular Toxicology (Print Edition). 21, 3, p. 145-155 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Vitamin C deficiency in weanling guinea pigs: differential expression of oxidative stress and DNA repair in liver and brain

    Lykkesfeldt, Jens, Trueba, G. P., Poulsen, H. E. & Christen, S., 2007, In: British Journal of Nutrition. 98, 6, p. 1116-1119 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. 2008
  81. Published

    Carotid Artery Intima-Media Thickness and Cutaneous Microvascular Function are Associated With Vitamin C Levels in Young Patients With Type 1 Diabetes

    Odermarsky, M., Lykkesfeldt, Jens & Liuba, P., 2008, Scientific Sessions 2008.

    Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research

  82. Published

    Does vitamin C matter? A quest for in vivo effects of vitamin C deficiency

    Lykkesfeldt, Jens, 2008, In: Free Radical Research. 42, S1, p. s23 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  83. Published

    Morphine reduces spinal c-fos expression dose-dependently during experimental laparotomy in pigs: a combined pharmacokinetic and surgical study

    Lykkegaard, K., Lykkesfeldt, Jens, Lauritzen, B. & Svendsen, O., 2008, In: Research in Veterinary Science. 84, 3, p. 457-464 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Utility of melatonin to treat surgical stress after major vascular surgery - a safety study

    Kücükakin, B., Lykkesfeldt, Jens, Nielsen, H. J., Reiter, R. J., Rosenberg, Jacob & Gögenur, Ismail, 2008, In: Journal of Pineal Research. 44, 4, p. 426-431 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. 2009
  86. Published

    C-Vitamin mod åreforkalkning

    Frikke-Schmidt, H. R. & Lykkesfeldt, Jens, 2009, In: Aktuel Naturvidenskab. 3, p. 26-29 4 p.

    Research output: Contribution to journal › Journal article › Communication

  87. Published

    Does vitamin C deficiency result in impaired brain development in infants?

    Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2009, In: Redox Report. 14, 1, p. 2-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Poor vitamin C status is associated with increased carotid intima-media thickness, decreased microvascular function, and delayed myocardial repolarization in young patients with type 1 diabetes

    Odermarsky, M., Lykkesfeldt, Jens & Liuba, P., 2009, In: American Journal of Clinical Nutrition. 90, 2, p. 447-452 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Role of marginal vitamin C deficiency in atherogenesis: In vivo models and clinical studies

    Frikke-Schmidt, H. R. & Lykkesfeldt, Jens, 2009, In: Basic & Clinical Pharmacology & Toxicology. 104, 6, p. 419-433 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Vitamin C deficiency in early postnatal life impairs spatial memory and reduces the number of hippocampal neurons in guinea pigs

    Tveden-Nyborg, Pernille, Jensen, Louise Kruse, Raida, Z., Villumsen, C. K., Larsen, J. O. & Lykkesfeldt, Jens, 2009, In: American Journal of Clinical Nutrition. 90, 3, p. 540-546 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. 2010
  92. Published

    Is vitamin C supplementation beneficial? lessons learned from randomised controlled trials

    Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2010, In: British Journal of Nutrition. 103, 9, p. 1251-1259 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Keeping the intracellular vitamin C at a physiologically relevant level in endothelial cell culture

    Frikke-Schmidt, H. R. & Lykkesfeldt, Jens, 2010, In: Analytical Biochemistry. 397, 1, p. 135-137 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    No effect of melatonin on oxidative stress after laparoscopic cholecystectomy: a randomized placebo-controlled trial

    Kücükakin, B., Klein, M., Lykkesfeldt, Jens, Reiter, R. J., Rosenberg, J. & Gögenür, I., 2010, In: Acta Anaesthesiologica Scandinavica. 54, 9, p. 1121-1127 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    No effect of melatonin to modify surgical-stress response after major vascular surgery: a randomised placebo-controlled trial

    Kücükakin, B., Wilhelmsen, M., Lykkesfeldt, Jens, Reiter, R. J., Rosenberg, J. & Gögenur, I., 2010, In: European Journal of Vascular and Endovascular Surgery. 40, 4, p. 461-467 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Obese Prone Rats on high- and low-fat diets gain weight equally

    Christensen, B. T., Hellgren, L., Sejrsen, K., Lykkesfeldt, Jens & Hansen, Axel Kornerup, 2010.

    Research output: Contribution to conference › Poster › Research

  97. Published

    Antioxidant supplementation does not alter endurance training adaptation

    Yfanti, C., Åkerström, T., Nielsen, S., Nielsen, A. R., Mounier, R., Mortensen, Ole Hartvig, Lykkesfeldt, Jens, Rose, A. J., Fischer, C. P. & Pedersen, Bente Klarlund, 1 Jul 2010, In: Medicine and Science in Sports and Exercise. 42, 7, p. 1388-95 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. 2011
  99. Published

    Animal models in pharmacology and toxicology

    Meyer, O. A., Svendsen, O. & Lykkesfeldt, Jens, 2011, Handbook of laboratory animal science: volume II: Animal models. Hau, J. & J. Schapiro, S. (eds.). 3. ed. ed. CRC Press, Vol. 2. p. 149-184 36 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  100. Published

    Effect of antioxidant supplementation on insulin sensitivity in response to endurance exercise training

    Yfanti, C., Nielsen, A. R., Åkerström, T., Nielsen, S., Rose, A. J., Richter, Erik A., Lykkesfeldt, Jens, Fischer, C. P. & Pedersen, Bente Klarlund, 2011, In: American Journal of Physiology: Endocrinology and Metabolism. 300, 5, p. E761-E770 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    Effect of vitamin C and iron chelation on diesel exhaust particle and carbon black induced oxidative damage and cell adhesion molecule expression in human endothelial cells

    Frikke-Schmidt, H. R., Roursgaard, Martin, Lykkesfeldt, Jens, Loft, Steffen, Nøjgaard, J. K. & Møller, Peter, 2011, In: Toxicology Letters. 203, 3, p. 181-189 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  102. Published

    Fluctuating hyperglycaemia increases oxidative stress response in lean rats compared to sustained hyperglycaemia despite lower glycaemic exposure

    Rakipovski, G., Raun, K. & Lykkesfeldt, Jens, 2011, In: Diabetes and Vascular Disease Research. 8, 4, p. 295-298 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  103. Published

    High dietary fat and cholesterol exacerbates chronic vitamin C deficiency in guinea pigs

    Frikke-Schmidt, H. R., Tveden-Nyborg, Pernille, Birck, M. M. & Lykkesfeldt, Jens, 2011, In: British Journal of Nutrition. 105, 1, p. 54-61 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  104. Published

    Reply to Hemilä by Lykkesfeldt and Poulsen

    Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2011, In: British Journal of Nutrition. 105, 3, p. 488 1 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  105. Published

    Storage-induced increase in biomarkers of oxidative stress and inflammation in red blood cell components

    Kücükakin, B., Kocak, V., Lykkesfeldt, Jens, Nielsen, H. J., Magnussen, K., Rosenberg, Jacob & Gögenür, I., 2011, In: Scandinavian Journal of Clinical & Laboratory Investigation. 71, 4, p. 299-303 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  106. Published

    The effect of altered gut flora on glucose intolerance in C57BL/6NTac mice

    Rune, Ida, Ellekilde, M., Hansen, Camilla Hartmann Friis, Nielsen, Dennis Sandris, Rolin, B. C., Lykkesfeldt, Jens & Hansen, Axel Kornerup, 2011. 1 p.

    Research output: Contribution to conference › Poster › Research

  107. Published

    Vitamin C in human nutrition

    Frikke-Schmidt, H. R., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2011, Vitamins in the prevention of human diseases. Herrmann, W. & Obeid, R. (eds.). De Gruyter, p. 323-362 40 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  108. Published

    Vitamin C - ascorbic acid

    Frikke-Schmidt, H., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens, Drake, V. J. & Frei, B., 28 Feb 2011, Vitamins in the Prevention of Human Diseases. Walter de Gruyter GmbH and Co. KG, p. 323-362 40 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  109. Published

    The effect of altered gut flora on glucose intolerance in C57BL/6NTac mice

    Rune, Ida, Nielsen, Dennis Sandris, Hansen, Axel Kornerup, Ellekilde, M., Lykkesfeldt, Jens, Hansen, Camilla Hartmann Friis & Rolin, B., Nov 2011. 1 p.

    Research output: Contribution to conference › Poster › Research

  110. 2012
  111. Published

    A sensitive venous bleeding model in haemophilia A mice: effects of two recombinant FVIII products (N8 and Advate®)

    Pastoft, A. E., Lykkesfeldt, Jens, Ezban, M., Tranholm, M., Whinna, H. C. & Lauritzen, B., 2012, In: Haemophilia. 18, 5, p. 782-788 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  112. Published

    Ascorbate and dehydroascorbic acid as biomarkers of oxidative stress: validity of clinical data depends on vacutainer system used

    Lykkesfeldt, Jens, 2012, In: Nutrition Research. 32, 1, p. 66-69 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  113. Published

    Ascorbate status modulates reticuloendothelial iron stores and response to deferasirox iron chelation in ascorbate-deficient rats

    Brewer, C., Otto-Duessel, M., Lykkesfeldt, Jens, Nick, H. & Wood, J. C., 2012, In: Experimental Hematology. 40, 10, p. 820-827 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  114. Published

    Chronic vitamin C deficiency does not accelerate oxidative stress in ageing brains of guinea pigs

    Tveden-Nyborg, Pernille, Andersen, S. H., Miyashita, N., Moos, T., Poulsen, Henrik Enghusen & Lykkesfeldt, Jens, 2012, In: Basic & Clinical Pharmacology & Toxicology Online. 110, 6, p. 524-529 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  115. Published

    Maternal vitamin C deficiency during pregnancy persistently impairs hippocampal neurogenesis in offspring of guinea pigs

    Tveden-Nyborg, Pernille, Vogt, L., Schjoldager, J. G., Jeannet, N., Andersen, S. H., Paidi, M. D., Christen, S. & Lykkesfeldt, Jens, 2012, In: P L o S One. 7, 10, 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  116. Published

    Oxidative stress response after laparoscopic versus conventional sigmoid resection: a randomized, double-blind clinical trial

    Madsen, M. T., Kücükakin, B., Lykkesfeldt, Jens, Rosenberg, J. & Gögenur, I., 2012, In: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques. 22, 3, p. 215-219 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  117. Published

    Poor antioxidant status exacerbates oxidative stress and inflammatory response to Pseudomonas aeruginosa lung infection in Guinea Pigs

    Jensen, Peter Østrup, Lykkesfeldt, Jens, Bjarnsholt, Thomas, Hougen, H. P., Høiby, Niels & Ciofu, Oana, 2012, In: Basic & Clinical Pharmacology & Toxicology. 110, 4, p. 353-358 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  118. Published

    Role of vitamin C and E supplementation on IL-6 in response to training

    Yfanti, C., Fischer, C. P., Nielsen, S., Åkerström, T., Nielsen, A. R., Veskoukis, A. S., Kouretas, D., Lykkesfeldt, Jens, Pilegaard, Henriette & Pedersen, Bente Klarlund, 2012, In: Journal of Applied Physiology. 112, 6, p. 990-1000 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  119. Published

    Vitamin C and its role in brain development and cognition

    Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2012, Nutrition and mental performance: a develomental perspective. Riby, L., Smith, M. & Foster, J. (eds.). Palgrave Macmillan, p. 29-52 24 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  120. Published

    What is the optimum intake of vitamin C in humans?

    Frei, B., Birlouez-Aragon, I. & Lykkesfeldt, Jens, 2012, In: Critical Reviews in Food Science and Nutrition. 52, 9, p. 815-829 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  121. 2013
  122. Published

    Ampicillin-improved glucose tolerance in diet-induced obese C57BL/6NTac mice is age dependent

    Rune, Ida, Hansen, Camilla Hartmann Friis, Ellekilde, M., Nielsen, Dennis Sandris, Skovgaard, K., Rolin, B. C., Lykkesfeldt, Jens, Josefsen, K., Christensen, B. T., Kihl, Pernille & Hansen, Axel Kornerup, 2013, In: Experimental Diabetes Research. 2013, 13 p., 319321.

    Research output: Contribution to journal › Journal article › Research › peer-review

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