Hans Bräuner
Prodekan for forskning
Faculty Service
Blegdamsvej 3
2200 København N.
- 2024
- Published
Characterization of the real-time internalization of nine GPCRs reveals distinct dependence on arrestins and G proteins
Møller, T. C., Moo, Ee Von, Inoue, A., Pedersen, M. F. & Bräuner, Hans, 2024, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1871, 1, 12 p., 119584.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-Activity Relationship Studies and Optimization of 4-Hydroxypyridones as GPR84 Agonists
Ieremias, L., Kaspersen, M. H., Manandhar, Asmita, Schultz-Knudsen, Katrine, Vrettou, C. I., Pokhrel, R., Heidtmann, C. V., Jenkins, L., Kanellou, C., Marsango, S., Li, Y., Bräuner, Hans, Ulven, Elisabeth Rexen, Milligan, G. & Ulven, Trond, 2024, In: Journal of Medicinal Chemistry. 67, 5, p. 3542-3570Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors
Alexander, S. P. H., Christopoulos, A., Davenport, A. P., Kelly, E., Mathie, A. A., Peters, J. A., Veale, E. L., Armstrong, J. F., Faccenda, E., Harding, S. D., Davies, J. A., Abbracchio, M. P., Abraham, G., Agoulnik, A., Alexander, W., Al-Hosaini, K., Bäck, M., Baker, J. G., Barnes, N. M., Bathgate, R. & 146 others, , Oct 2023, In: British Journal of Pharmacology. 180 Suppl 2, p. S23-S144Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endocytic proteins mediating GPR15 receptor internalization provide insight into the underlying mechanisms
Deng, Y., Moo, Ee Von, Inoue, A. & Bräuner, Hans, 2023, In: FEBS Letters. 597, 11, p. 1528-1540Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacological characterization of novel small molecule agonists and antagonists for the orphan receptor GPR139
Pallareti, L., Rath, T. F., Trapkov, Boris, Tsonkov, T., Nielsen, A. T., Harpsøe, Kasper, Gentry, P. R., Bräuner, Hans, Gloriam, David E. & Foster, S. R., 2023, In: European Journal of Pharmacology. 943, 175553.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure–activity relationship of GPR15L peptide analogues and investigation of their interaction with the GPR15 receptor
Deng, Y., Perez Almeria, C. V., van Gijzel, L., Schaller, Kay, Vedel, L., Gloriam, David E., Ulven, Trond & Bräuner, Hans, 2023, In: Basic and Clinical Pharmacology and Toxicology. 132, 6, p. 459-471Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Delineation of the GPR15 receptor-mediated Gα protein signalling profile in recombinant mammalian cells
Deng, Y., Moo, Ee Von, Almería, C. V. P., Gentry, P. R., Vedel, L., Mathiesen, Jesper M. & Bräuner, Hans, 2022, In: Basic and Clinical Pharmacology and Toxicology. 131, 2, p. 104-113Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of a medium throughput whole-cell microtiter plate Thr286 autophosphorylation assay for CaMKIIα using ELISA
Palmelund, L. B., van Woerden, G. M., Bräuner, Hans & Wellendorph, Petrine, 2022, In: Journal of Pharmacological and Toxicological Methods. 118, 8 p., 107226.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ligand-directed bias of G protein signaling at the dopamine D2 receptor
Moo, Ee Von, Harpsøe, Kasper, Hauser, Alexander Sebastian, Masuho, I., Bräuner, Hans, Gloriam, David E. & Martemyanov, K. A., 2022, In: Cell Chemical Biology. 29, 2, p. 226-238Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular insights into ligand recognition and G protein coupling of the neuromodulatory orphan receptor GPR139
Zhou, Y., Daver, H., Trapkov, B., Wu, L., Wu, M., Harpsøe, Kasper, Gentry, P. R., Liu, K., Larionova, M., Liu, J., Chen, N., Bräuner, Hans, Gloriam, David E., Hua, T. & Liu, Z. J., 2022, In: Cell Research. 32, 2, p. 210-213Research output: Contribution to journal › Letter › Research › peer-review
- Published
Somatostatin venom analogs evolved by fish-hunting cone snails: From prey capture behavior to identifying drug leads
Ramiro, Iris Bea L. , Bjørn-Yoshimoto, Walden, Imperial, J. S., Gajewiak, J., Salcedo, P. F., Watkins, M., Taylor, D., Resager, W., Ueberheide, B., Bräuner, Hans, Whitby, F. G., Hill, C. P., Martin, L. F., Patwardhan, A., Concepcion, G. P., Olivera, B. M. & Safavi-Hemami, H., 2022, In: Science Advances. 8, 12, 16 p., eabk1410.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of CRISPR/Cas9-edited HEK293 cells reveals that both conventional and novel protein kinase C isozymes are involved in mGlu5a receptor internalization
van Senten, Jeffrey Roy, Møller, T. C., Moo, Ee Von, Seiersen, S. D. & Bräuner, Hans, 2022, In: Journal of Biological Chemistry. 298, 10, 16 p., 102466.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Positive allosteric modulators of metabotropic glutamate receptor 5 as tool compounds to study signaling bias
Arsova, A., Møller, T. C., Hellyer, S. D., Vedel, L., Foster, S. R., Hansen, J. L., Bräuner, Hans & Gregory, K. J., 1 May 2021, In: Molecular Pharmacology. 99, 5, p. 328-241Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Arrestin-Dependent and -Independent Internalization of G Protein–Coupled Receptors: Methods, Mechanisms, and Implications on Cell Signaling
Moo, Ee Von, van Senten, Jeffrey Roy, Bräuner, Hans & Møller, T. C., 2021, In: Molecular Pharmacology. 99, 4, p. 242-255Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Asymmetric activation of the calcium-sensing receptor homodimer
Gao, Y., Robertson, M. J., Rahman, Sabrina Nalini, Seven, A. B., Zhang, C., Meyerowitz, J. G., Panova, O., Hannan, F. M., Thakker, R. V., Bräuner, Hans, Mathiesen, Jesper M. & Skiniotis, G., 2021, In: Nature. 595, p. 455-459Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 Val8: A Biased GLP-1R Agonist with Altered Binding Kinetics and Impaired Release of Pancreatic Hormones in Rats
van der Velden, W. J. C., Smit, F. X., Christiansen, Charlotte Bayer, Møller, T. C., Hjortø, Gertrud Malene, Larsen, Olav, Schiellerup, S. P., Bräuner, Hans, Holst, Jens Juul, Hartmann, Bolette, Frimurer, Thomas Michael & Rosenkilde, Mette, 2021, In: ACS Pharmacology & Translational Science. 4, 1, p. 296-313 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
- Published
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors
Alexander, S. P., Christopoulos, A., Davenport, A. P., Kelly, E., Mathie, A., Peters, J. A., Veale, E. L., Armstrong, J. F., Faccenda, E., Harding, S. D., Pawson, A. J., Southan, C., Davies, J. A., Abbracchio, M. P., Alexander, W., Al-Hosaini, K., Bäck, M., Barnes, N. M., Bathgate, R., Beaulieu, J-M. & 135 others, , 2021, In: British Journal of Pharmacology. 178 , S1, p. S27-S156Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Calcium-Sensing Receptor Is Essential for Calcium and Bicarbonate Sensitivity in Human Spermatozoa
Boisen, I. M., Rehfeld, Anders Aagaard, Mos, I., Poulsen, N. N., Nielsen, J. E., Schwarz, Peter, Rejnmark, L., Dissing, Steen, Bach-Mortensen, P., Juul, Anders, Bräuner, Hans, Lanske, B. & Blomberg Jensen, M., 2021, In: The Journal of clinical endocrinology and metabolism. 106, 4, p. e1775-e1792Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
International Union of Basic and Clinical Pharmacology. CVIII. Calcium-Sensing Receptor Nomenclature, Pharmacology, and Function
Leach, K., Hannan, F. M., Josephs, T. M., Keller, A. N., Møller, T. C., Ward, D. T., Kallay, E., Mason, R. S., Thakker, R. V., Riccardi, D., Conigrave, A. D. & Bräuner, Hans, Jul 2020, In: Pharmacological Reviews. 72, 3, p. 558-604 47 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Heterozygous Mutation (Q459R) in the Calcium-Sensing Receptor Gene Causes Familial Hypocalciuric Hypercalcemia 1 (FHH1)
Boisen, I. M., Mos, I., Lerche-Black, E. M., Juul, Anders, Bräuner, Hans & Blomberg Jensen, M., 1 Apr 2020, In: The Journal of clinical endocrinology and metabolism. 105, 4, p. e1322-e1330Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel approaches leading towards peptide GPCR de-orphanisation
Hauser, Alexander Sebastian, Gloriam, David E., Bräuner, Hans & Foster, S. R., 1 Mar 2020, In: British Journal of Pharmacology. 177, 5, p. 961-968 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Biased agonism of clinically approved μ-opioid receptor agonists and TRV130 is not controlled by binding and signaling kinetics
Pedersen, M. F., Wrobel, T. M., Marcher, Emil, Pedersen, D. S., Møller, T. C., Gabriele, F., Pedersen, H., Matosiuk, D., Foster, S. R., Bouvier, M. & Bräuner, Hans, 2020, In: Neuropharmacology. 166, 13 p., 107718.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Delineation of molecular determinants for FR900359 inhibition of Gq/11 unlocks inhibition of Gαs
Boesgaard, M. W., Harpsøe, Kasper, Malmberg, M., Underwood, C. R., Inoue, A., Mathiesen, Jesper M., König, G. M., Kostenis, E., Gloriam, David E. & Bräuner, Hans, 2020, In: Journal of Biological Chemistry. 295, 40, p. 13850-13861Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detailed in vitro pharmacological characterization of clinically tested negative allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5)
Arsova, A., Møller, T. C., Vedel, L., Hansen, J. L., Foster, S. R., Gregory, K. J. & Bräuner, Hans, 2020, In: Molecular Pharmacology. 98, 1, p. 49-60Research output: Contribution to journal › Journal article › Research › peer-review
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Kemogenomik: Receptoren set fra lægemiddelstoffets synspunkt
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