Fredrik Björkling

Fredrik Björkling

Emeritus

ORCID: 0000-0001-7018-8334

Publication year:
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1 - 25 out of 35Page size: 25
  1. 2010
  2. Published

    Anticancer agents

    Björkling, Fredrik & Jensen, L. H., 2010, Textbook of drug design and discovery. Krogsgaard-Larsen, P., Strømgaard, K. & Madsen, U. (eds.). 4 ed. Boca Raton: CRC Press, p. 375-392

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

  3. Published

    Early detection of response to experimental chemotherapeutic Top216 with [18F]FLT and [18F]FDG PET in human ovary cancer xenografts in mice

    Wessel, Mette Munk, Erichsen, K. D., Björkling, Fredrik, Madsen, J., Jensen, P. B., Højgaard, Liselotte, Sehested, M. & Kjær, Andreas, 1 Jan 2010, In: P L o S One. 5, 9, p. e12965

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Synthesis and antitumor effect in vitro and in vivo of substituted 1,3-dihydroindole-2-ones

    Christensen, M. K., Erichsen, K. D., Trojel-Hansen, C., Tjørnelund, J., Nielsen, S. J., Frydenvang, Karla Andrea, Johansen, Tommy Nørskov, Nielsen, Birgitte, Sehested, M., Jensen, P. B., Ikaunieks, M., Zaichenko, A., Loza, E., Kalvinsh, I. & Björkling, Fredrik, 14 Oct 2010, In: Journal of Medicinal Chemistry. 53, 19, p. 7140-7145 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase

    Olesen, U. H., Petersen, J. G., Garten, A., Kiess, W., Yoshino, J., Imai, S., Christensen, M. K., Fristrup, P., Thougaard, A. V., Björkling, Fredrik, Jensen, P. B., Nielsen, S. J. & Sehested, M., 10 Dec 2010, In: BMC Cancer. 10, p. 677 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2012
  7. Published

    Inhibitors of human histone deacetylase with potent activity against the African trypanosome Trypanosoma brucei

    Kelly, J., Taylor, M. C., Horn, D., Loza, E., Kalvinsh, I. & Björkling, Fredrik, 2012, In: Bioorganic & Medicinal Chemistry Letters. 22, 5, p. 1886–1890 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Prediction of drug efficacy for cancer treatment based on comparative analysis of chemosensitivity and gene expression data

    Wan, P., Li, Q., Larsen, J. E. P., Eklund, A. C., Parlesak, A., Rigina, O., Nielsen, S. J., Björkling, Fredrik & Jonsdottir, S. O., 2012, In: Bioorganic & Medicinal Chemistry. 20, 1, p. 167-176 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    [18F]FLT PET for Non-Invasive Assessment of Tumor Sensitivity to Chemotherapy: Studies with Experimental Chemotherapy TP202377 in Human Cancer Xenografts in Mice: studies with experimental chemotherapy TP202377 in human cancer xenografts in mice

    Wessel, Mette Munk, Erichsen, K. D., Björkling, Fredrik, Madsen, J., Jensen, P. B., Sehested, M., Højgaard, Liselotte & Kjær, Andreas, 2012, In: P L o S One. 7, 11, p. e50618 e50618.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 2013
  11. Published

    Imaging of treatment response to the combination of carboplatin and paclitaxel in human ovarian cancer xenograft tumors in mice using FDG and FLT PET

    Wessel, Mette Munk, Erichsen, K. D., Björkling, Fredrik, Madsen, J., Jensen, Peter, Sehested, M., Højgaard, Liselotte & Kjær, Andreas, 2013, In: P L o S One. 8, 12, 9 p., e85126.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    [18F]FDG and [18F]FLT positron emission tomography imaging following treatment with belinostat in human ovary cancer xenografts in mice

    Wessel, Mette Munk, Erichsen, K. D., Johnbeck, C. B., Björkling, Fredrik, Madsen, J., Jensen, Peter, Sehested, M., Højgaard, Liselotte & Kjær, Andreas, 2013, In: B M C Cancer. 13, p. 1-9 10 p., 168.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    [18F]FLT and [18F]FDG PET for non-invasive treatment monitoring of the nicotinamide phosphoribosyltransferase inhibitor APO866 in human xenografts

    Erichsen, K. D., Johnbeck, C. B., Björkling, Fredrik, Madsen, J., Bzorek, M., Jensen, Peter, Højgaard, Liselotte, Sehested, M., Kjær, Andreas & Wessel, Mette Munk, 2013, In: P L o S One. 8, 1, p. 1-8 9 p., e53410.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 2015
  15. Published

    Jagten på kongens efterfølger

    Franzyk, Henrik, Björkling, Fredrik, Nielsen, J. & Nielsen, Peter E., 2015, In: Lægemiddelforskning. 2015, p. 24-27 4 p.

    Research output: Contribution to journal › Journal article › Communication

  16. 2016
  17. Published

    Novel Agonist Bioisosteres and Common Structure-Activity Relationships for The Orphan G Protein-Coupled Receptor GPR139

    Shehata, M. A., Jensen, A. C. N., Lissa, D., Bisig, C., Isberg, V., Andersen, K. B., Harpsøe, Kasper, Björkling, Fredrik, Bräuner, Hans & Gloriam, David E., 10 Nov 2016, In: Scientific Reports. 6, p. 1-13 13 p., 36681.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. 2017
  19. Published

    Antisense PNA antibiotics against multiresistant Gram-negative bacteria

    Nielsen, Peter E., Björkling, Fredrik & Franzyk, Henrik, 2017, In: International Journal of Molecular Medicine. 40, Suppl. 1, p. S22 1 p., Abstract 169.

    Research output: Contribution to journal › Conference abstract in journal › Research

  20. 2018
  21. Published

    Non-natural Amino Acid and Peptoid Building Blocks for Optimization of the Cell-Penetrating (R-X-R)n Motif

    Wester, A., Björkling, Fredrik, Nieslen, P. & Franzyk, Henrik, Sep 2018, In: Journal of Peptide Science. 24, p. S94-S94

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  22. 2019
  23. Published

    Microwave-assisted solid-phase synthesis of antisense acpP peptide nucleic acid-peptide conjugates active against colistin- and tigecycline-resistant E. coli and K. pneumoniae

    Hansen, A. M., Bonke, G., Hogendorf, W. F. J., Björkling, Fredrik, Nielsen, J., Kongstad, Kenneth Thermann, Zabicka, D., Tomczak, M., Urbas, M., Nielsen, Peter E. & Franzyk, Henrik, 2019, In: European Journal of Medicinal Chemistry. 168, p. 134-145 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Triphenylcarbenium Tetrafluoroborate as an Efficient Catalyst in the Regioselective Reductive Ring Opening of Benzylidene Acetals of Carbohydrates

    Thota, N., Björkling, Fredrik & Kankala, S., 2019, In: ChemistrySelect. 4, 27, p. 7976-7980

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Silver carbene complexes: An emerging class of anticancer agents

    Kankala, S., Thota, N., Björkling, Fredrik, Taylor, M. K., Vadde, R. & Balusu, R., Mar 2019, In: Drug Development Research. 80, 2, p. 188-199

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Peptide/Peptoid Hybrid Oligomers: The Influence of Hydrophobicity and Relative Side-Chain Length on Antibacterial Activity and Cell Selectivity

    Frederiksen, N., Hansen, Paul Robert, Björkling, Fredrik & Franzyk, Henrik, 4 Dec 2019, In: Molecules (Print Archive Edition). 24, 18 p., 4429.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. 2020
  28. Published

    Alternating Cationic-Hydrophobic Peptide/Peptoid Hybrids: Influence of Hydrophobicity on Antibacterial Activity and Cell Selectivity

    Frederiksen, N., Hansen, Paul Robert, Zabicka, D., Tomczak, M., Urbas, M., Domraceva, I., Björkling, Fredrik & Franzyk, Henrik, 2020, In: ChemMedChem. 15, 24, p. 2544-2561

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Discovery of Novel Non-Steroidal Cytochrome P450 17A1 Inhibitors as Potential Prostate Cancer Agents

    Wróbel, T. M., Rogova, O., Andersen, Kasper Langebjerg, Yadav, R., Brixius-Anderko, S., Scott, E. E., Olsen, L., Jørgensen, Flemming Steen & Björkling, Fredrik, 2020, In: International Journal of Molecular Sciences . 21, 14, p. 1-11 4868.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Synthesis of novel fluorophenylpyrazole-picolinamide derivatives and determination of their anticancer activity

    Kankala, S., Rama, K. R., Kesari, C., Björkling, Fredrik, Nerella, S., Gundepaka, P., Guguloth, H. & Thota, N., 2020, In: Synthetic Communications. 50, 19, p. 2997-3006 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. 2021
  32. Published

    Evaluation of 1H-Triazole-1-[N,N'-Bis(tert-butoxycarbonyl)]carboxamidine in Solution-Phase and On-Resin Guanidinylation

    Wester, A., Björkling, Fredrik & Franzyk, Henrik, 2021, In: The Journal of Organic Chemistry. 86, 21, p. 14371–14380

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Optimized Synthesis of Fmoc/Boc-Protected PNA Monomers and their Assembly into PNA Oligomers.

    Shaikh, Ashif Yasin, Björkling, Fredrik, Nielsen, Peter E. & Franzyk, Henrik, 2021, In: European Journal of Organic Chemistry. 2021, 19, p. 2792-2801 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Peptide/β-Peptoid Hybrids with Ultrashort PEG-Like Moieties: Effects on Hydrophobicity, Antibacterial Activity and Hemolytic Properties

    Frederiksen, N., Louka, S., Mudaliar, C., Domraceva, I., Kreicberga, A., Pugovics, O., Żabicka, D., Tomczak, M., Wygoda, W., Björkling, Fredrik & Franzyk, Henrik, 2021, In: International Journal of Molecular Sciences. 22, 13, 17 p., 7041.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Structural Basis of Metallo-β-lactamase Inhibition by N-Sulfamoylpyrrole-2-carboxylates

    Farley, A. J. M., Ermolovich, Y., Calvopiña, K., Rabe, P., Panduwawala, T., Brem, J., Björkling, Fredrik & Schofield, C. J., 2021, In: ACS Infectious Diseases. 7, 6, p. 1809–1817

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 8863737