[18F]FLT PET for Non-Invasive Assessment of Tumor Sensitivity to Chemotherapy: Studies with Experimental Chemotherapy TP202377 in Human Cancer Xenografts in Mice: studies with experimental chemotherapy TP202377 in human cancer xenografts in mice

Research output: Contribution to journalJournal articleResearchpeer-review

3'-deoxy-3'-[¹⁸F]fluorothymidine ([18F]FLT) is a tracer used to assess cell proliferation in vivo. The aim of the study was to use [18F]FLT positron emission tomography (PET) to study non-invasively early anti-proliferative effects of the experimental chemotherapeutic agent TP202377 in both sensitive and resistant tumors.
Original languageEnglish
Article numbere50618
JournalP L o S One
Issue number11
Pages (from-to)e50618
Publication statusPublished - 2012

    Research areas

  • Animals, Antineoplastic Agents, Biological Transport, Cell Line, Tumor, Cell Proliferation, Dideoxynucleosides, Female, Gene Expression Regulation, Neoplastic, Humans, Indoles, Ki-67 Antigen, Mice, Ovarian Neoplasms, Positron-Emission Tomography, Thymidine Kinase, Time Factors, Tomography, X-Ray Computed, Treatment Failure, Tumor Burden, Xenograft Model Antitumor Assays

ID: 45864200