[18F]FLT PET for Non-Invasive Assessment of Tumor Sensitivity to Chemotherapy: Studies with Experimental Chemotherapy TP202377 in Human Cancer Xenografts in Mice: studies with experimental chemotherapy TP202377 in human cancer xenografts in mice
Research output: Contribution to journal › Journal article › Research › peer-review
3'-deoxy-3'-[¹⁸F]fluorothymidine ([18F]FLT) is a tracer used to assess cell proliferation in vivo. The aim of the study was to use [18F]FLT positron emission tomography (PET) to study non-invasively early anti-proliferative effects of the experimental chemotherapeutic agent TP202377 in both sensitive and resistant tumors.
|Journal||P L o S One|
|Publication status||Published - 2012|
- Animals, Antineoplastic Agents, Biological Transport, Cell Line, Tumor, Cell Proliferation, Dideoxynucleosides, Female, Gene Expression Regulation, Neoplastic, Humans, Indoles, Ki-67 Antigen, Mice, Ovarian Neoplasms, Positron-Emission Tomography, Thymidine Kinase, Time Factors, Tomography, X-Ray Computed, Treatment Failure, Tumor Burden, Xenograft Model Antitumor Assays