Dorte Frees

Dorte Frees

Associate Professor

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    Publication year:
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    1 - 50 out of 85Page size: 50
    1. 1999
    2. Published

      ClpP participaytes in the degradation of misfolded protein in Lactococcuss lactis

      Frees, Dorte & Ingmer, Hanne, 1999, In: Molecular Microbiology. 31, 1, p. 79 - 87 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. 2001
    4. Published

      Inactivation of a gene that is highly conserved in Gram-positive bacteria stimulates degradation of non-native proteins and concomitantly increases stress tolerance in Lactococcus lactis

      Frees, Dorte, Varmanen, P. & Ingmer, Hanne, 2001, In: Molecular Microbiology. 41, 1, p. 93-103 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. 2003
    6. Published

      Alternative roles of CIpX and CIpP in Staphylococus aureus stress toelrance and virulence.

      Frees, Dorte, Saara, N. A. Q., Philip, J. H. & Ingmer, Hanne, 2003, In: Molecular Microbiology. (2003) 48 (6), p. 1565 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Heat and DNA damage induction of the LexA-like regulator HdiR from Lactococcus lactis is mediated by RecA and ClpP

      Savijoki, K., Ingmer, Hanne, Frees, Dorte, Vogensen, Finn Kvist, Palva, A. & Varmanen, P., 2003, In: Molecular Microbiology. 50, 2, p. s.609-621 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Identification of proteins induced at low pH in Lactococcus lactis

      Frees, Dorte, Vogensen, Finn Kvist & Ingmer, Hanne, 2003, In: International Journal of Food Microbiology. 87, 87, p. 293-300 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Stress toelrance mechanisms influencing virulence and survival of food borne pathogens

      Frees, Dorte, Varmanen, P. ;., SavijokiK.;, Andersen, M. T., Brønsted, L. & Ingmer, Hanne, 2003. 1 p.

      Research output: Contribution to conference › Paper › Research

    10. 2004
    11. Published

      Clp ATPases are required for stress tolerance, intracellular replication and biofilm formation in Staphylococcus aureus

      Frees, Dorte, Chastanet, A., Quzi, S., Sørensen, K., Hill, P., Msadek, T. & Ingmer, Hanne, 2004, In: Molecular Microbiology. 54, 5, p. 1445-1462 18 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. 2005
    13. Published

      Salmonella isolates with different behavior in adhesion to surfaces studied by DNA micro array assisted analysis

      Holmstrøm, K., Olsen, K. N., Meldgaard, H., Bagge-Ravn, D., Frees, Dorte, Lauritsen, D., Gram, L. & Olsen, John Elmerdahl, 2005. 1 p.

      Research output: Contribution to conference › Conference abstract for conference › Research

    14. Published

      Global virulence regulation in Staphylococcus aureus: pinpointing the roles of ClpP and ClpX in the sar/agr regulatory network

      Frees, Dorte, Sørensen, K. & Ingmer, Hanne, 2005, In: Infection and Immunity. 73, 12, p. 8100-8108 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Staphylococcus aureus ClpYQ plays a minor role in stress survival

      Frees, Dorte, Thomsen, Line Elnif & Ingmer, Hanne, 2005, In: Archives of Microbiology. 183, 4, p. 286-291 6 p.

      Research output: Contribution to journal › Journal article › Research

    16. 2006
    17. Published

      Identification of the ClpX Regulon in Staphylococcus aureus

      Jelsbak, L., Thomsen, Line Elnif, Ingmer, Hanne, Donat, S., Ohlsen, K. & Frees, Dorte, 2006. 1 p.

      Research output: Contribution to conference › Poster › Research

    18. Published

      Spx is a global effector impacting stress tolerance and biofilm formation in Staphylococcus aureus

      Pamp, S. J., Frees, Dorte, Engelmann, S., Hecker, M. & Ingmer, Hanne, 2006, In: Journal of Bacteriology. 188, 13, p. 4861-4870 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. 2007
    20. Published

      Clp ATPases and ClpP proteolytic complexes regulate vital biological processes in low GC, Gram-positive bacteria

      Frees, Dorte, Savijoki, K., Varmanen, P. & Ingmer, Hanne, 2007, In: Molecular Microbiology. 63, 5, p. 1285-1295 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      SpxB regulates O-acetylation-dependent resistance of Lactococcus lactis peptidoglycan to hydrolysis

      Veiga, P., Bulbarela-Sampieri, C., Furlan, S., Maisons, A., Chapot-Chartier, M., Erkelenz, M., Mervelet, P., Noirot, P., Frees, Dorte, Kuipers, O. P., Kok, J., Gruss, A., Buist, G. & Kulakauskas, S., 2007, In: Journal of Biological Chemistry. 282, 27, p. 19342-19354 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      The role of ClpX in Staphylococcus aureus stress response and virulence

      Rasmussen, T., Frees, Dorte & Thomsen, Line Elnif, 2007. 1 p.

      Research output: Contribution to conference › Poster › Research

    23. 2008
    24. Published

      Investigation of correlation between gene expressions of 162 selected genes and survival and colonization abilities of Salmonella strains in the food chain

      Olsen, John Elmerdahl, Gram, L., Frees, Dorte & Holmstrøm, K., 2008, The 21st International ICFMH Symposium "Evolving Microbial Food Quality and Safety": Programme and Abstract Book. p. 164 1 p.

      Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research

    25. Published

      Simple plate assay for identification of new compounds used in anti-virulence therapy of Staphylococcus aureus

      Nielsen, A., Nielsen, K. F., Frees, Dorte, Larsen, T. O. & Ingmer, Hanne, 2008. 1 p.

      Research output: Contribution to conference › Paper › Research › peer-review

    26. Published

      Simple plate assay for identification of new compounds used in anti-virulence therapy of Staphylococcus aureus

      Nielsen, A., Nielsen, K. F., Frees, Dorte, Larsen, T. O. & Ingmer, Hanne, 2008.

      Research output: Contribution to conference › Poster › Research

    27. Published

      Simple plate assay for identification of new compounds used in anti-virulence therapy of Staphylococcus aureus

      Nielsen, A., Nielsen, K. F., Frees, Dorte, Larsen, T. O. & Ingmer, Hanne, 2008.

      Research output: Contribution to conference › Poster › Research

    28. 2009
    29. Published

      The role of Spi-6 and a putative type six secretion system in Salmonella serotype Gallinarum virulence

      Olsen, John Elmerdahl, Kristensen, B. M. & Frees, Dorte, 2009, ASM conference on Salmonella: Biology, Pathogenesis & Prevention. p. 50 1 p.

      Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research

    30. 2010
    31. Published

      A hitherto not recognized phenotype of spvA in Salmonella

      Frees, Dorte, Gram, L., Holmstrøm, K. & Olsen, John Elmerdahl, 2010, Proceedings: 13S international symposium salmonella and salmonellosis. p. 33-34 2 p.

      Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research

    32. Published

      Distribution, expression and secretion of the RTX-toxin GtxA among members of the genus Gallibacterium

      Kristensen, B. M., Frees, Dorte & Bojesen, Anders Miki, 2010, Pathogenesis of bacterial diseases in animals. p. 22 1 p.

      Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research

    33. Published

      Growth phase-dependent regulation of the global virulence regulator Rot in clinical isolates of Staphylococcus aureus

      Jelsbak, L., Hemmingsen, L., Donat, S., Ohlsen, K., Boye, K., Westh, H., Ingmer, Hanne & Frees, Dorte, 2010, In: International Journal of Medical Microbiology. 300, 4, p. 229-236 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      GtxA from Gallibacterium anatis, a cytolytic RTX-toxin with a novel domain organisation

      Kristensen, B. M., Frees, Dorte & Bojesen, Anders Miki, 2010, In: Veterinary Research. 41, 25, 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Method for screening compounds that influence virulence gene expression in Staphylococcus aureus

      Nielsen, A., Nielsen, K. F., Frees, Dorte, Larsen, T. O. & Ingmer, Hanne, 2010, In: Antimicrobial Agents and Chemotherapy. 54, 1, p. 509-512 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      PhD course "Infection Microbiology": time schedule for module A, 2010

      Frees, Dorte, Nielsen, M. & Thomsen, Line Elnif, 2010, Department of Veterinary Disease Biology, University of Copenhagen. 72 p.

      Research output: Book/Report › Compendium/lecture notes › Education

    37. Published

      The chaperone ClpX stimulates expression of Staphylococcus aureus protein A by rot dependent and independent pathways

      Jelsbak, L., Ingmer, Hanne, Valihrach, L., Cohn, M. T., Christiansen, M. H. G., Kallipolitis, B. H. & Frees, Dorte, 2010, In: PLoS ONE. 5, 9, 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. 2011
    39. Published

      A porcine model of acute, haematogenous, localized osteomyelitis due to Staphylococcus aureus: a pathomorphological study

      Jensen, Louise Kruse, Frees, Dorte, Aalbæk, Bent, Koch, J., Iburg, T. M., Nielsen, O. L., Leifsson, Páll S. & Jensen, Henrik Elvang, 2011, In: APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. 119, 2, p. 111-118 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Clp-dependent proteolysis of the LexA N-terminal domain in Staphylococcus aureus

      Cohn, M. T., Kjelgaard, P. M., Frees, Dorte, Penadés, J. R. & Ingmer, Hanne, 2011, In: Microbiology. 157, 3, p. 677-684 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Expression and secretion of the RTX-toxin GtxA among members of the genus Gallibacterium

      Kristensen, B. M., Frees, Dorte & Bojesen, Anders Miki, 2011, In: Veterinary Microbiology. 153, 1-2, p. 116-123 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Searching for small sB-regulated genes in Staphylococcus aureus

      Nielsen, J. S., Christiansen, M. H. G., Bonde, M., Gottschalk, S., Frees, Dorte, Thomsen, Line Elnif & Kallipolitis, B. H., 2011, In: Archives of Microbiology. 193, 1, p. 23-34 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. 2012
    44. Published

      A porcine model of heamatogenous osteomyelitis: pathogenesis and pathology

      Jensen, Louise Kruse, Koch, J., Frees, Dorte, Aalbæk, Bent, Nielsen, O. L., Leifsson, Páll S., Buelund, Lene Elisabeth, Svalastoga, Eiliv Lars & Jensen, Henrik Elvang, 2012. 1 p.

      Research output: Contribution to conference › Poster › Research

    45. Published

      Antibiotic-mediated selection of quorum-sensing-negative Staphylococcus aureus

      Paulander, W. E. A., Varming, A. N., Bæk, K. T., Haaber, J. K., Frees, Dorte & Ingmer, Hanne, 2012, In: mBio. 3, 6, p. e00459-12 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Local osteogenic expression of cyclooxygenase-2 and systemic response in porcine models of osteomyelitis

      Jensen, Louise Kruse, Iburg, T. M., Nielsen, O. L., Leifsson, Páll S., Dahl-Pedersen, Kirstin, Koch, J., Frees, Dorte, Aalbæk, Bent, Heegaard, P. M. H. & Jensen, Henrik Elvang, 2012, In: Prostaglandins & Other Lipid Mediators. 97, 3-4, p. 103-108 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      New insights into Staphylococcus aureus stress tolerance and virulence regulation from an analysis of the role of the ClpP protease in the strains Newman, COL, and SA564

      Frees, Dorte, Andersen, J. H., Hemmingsen, L., Koskenniemi, K., Bæk, K. T., Muhammed, Musemma Kedir, Gudeta, D. D., Nyman, T. A., Sukura, A., Varmanen, P. & Savijoki, K., 2012, In: Journal of Proteome Research. 11, 1, p. 95-108 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Norlichexanthone modulate Staphylococcus aureus virulence gene expression possibly via agr and sae

      Nielsen, A., Ifrah, D., Friberg, C., Larsen, T. O., Novick, R. P., Frøkiær, Hanne, Frees, Dorte, Hede, N. G. & Ingmer, Hanne, 2012.

      Research output: Contribution to conference › Poster › Research

    49. Published

      Pathology and biofilm formation in a porcine model of staphylococcal osteomyelitis

      Johansen, L. K., Koch, J., Frees, Dorte, Aalbæk, Bent, Nielsen, O. L., Leifsson, Páll S., Iburg, T. M., Svalastoga, Eiliv Lars, Buelund, Lene Elisabeth, Bjarnsholt, Thomas, Høiby, Niels & Jensen, Henrik Elvang, 2012, In: Journal of Comparative Pathology. 147, 2-3, p. 343-353 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Planktonic aggregates of Staphylococcus aureus protect against common antibiotics

      Haaber, J. K., Cohn, M. T., Frees, Dorte, Andersen, Thorbjørn Joest & Ingmer, Hanne, 2012, In: P L o S One. 7, 7, 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. Published

      The YjbH adaptor protein enhances proteolysis of the transcriptional regulator Spx in Staphylococcus aureus

      Engman, J., Rogstam, A. H., Frees, Dorte, Ingmer, Hanne & Wachenfeldt, C. V., 2012, In: Journal of Bacteriology. 194, 5, p. 1186-1194 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. Published

      Solonamide B Inhibits Quorum Sensing and reduces Staphylococcus aureus mediated killing of Human Neutrophils

      Nielsen, A., Månsson, M., Gram, L., Larsen, T. O., Phipps, R. K., Frees, Dorte, Frøkiær, Hanne & Ingmer, Hanne, Aug 2012.

      Research output: Contribution to conference › Poster › Research

    53. 2013
    54. Published

      Bacterial proteases and virulence

      Frees, Dorte, Brøndsted, Lone & Ingmer, Hanne, 2013, Regulated proteolysis in microorganisms. Dougan, D. A. (ed.). Springer, p. 161-192 32 p. (Subcellular biochemistry, Vol. 66).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    55. Published

      Genetic variation in the Staphylococcus aureus 8325 strain lineage revealed by whole-genome sequencing

      Bæk, K. T., Frees, Dorte, Renzoni, A., Barras, C., Rodriguez, N., Manzano, C. & Kelley, W. L., 2013, In: P L o S One. 8, 9, 16 p., e77122.

      Research output: Contribution to journal › Journal article › Research › peer-review

    56. Published

      Regulation of host hemoglobin binding by the Staphylococcus aureus Clp proteolytic system

      Farrand, A. J., Reniere, M. L., Ingmer, Hanne, Frees, Dorte & Skaar, E. P., 2013, In: Journal of Bacteriology. 195, 22, p. 5041-5050 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    57. Published

      The role of Serpine-1 and Tissue inhibitor of metalloproteinase type-1 in early host responses to Staphylococcus aureus intracutaneous infection of mice

      Harslund, J. L. F., Frees, Dorte, Leifsson, Páll S., Offenberg, H. K., Rømer, M. U. K., Brünner, N. & Olsen, John Elmerdahl, 2013, In: Pathogens and Disease. 68, 3, p. 96-104 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    58. Published

      Therapy of haematogenous osteomyelitis: a comparative study in a porcine model and Angolan children

      Jensen, Louise Kruse, Koch, J., Kirketerp-Møller, K., Wamsler, O. J., Nielsen, O. L., Leifsson, Páll S., Frees, Dorte, Aalbæk, Bent & Jensen, Henrik Elvang, 2013, In: In Vivo. 27, 3, p. 305-312 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    59. Published

      Trapping and proteomic identification of cellular substrates of the ClpP protease in Staphylococcus aureus

      Feng, J., Michalik, S., Varming, A. N., Andersen, J. H., Albrecht, D., Jelsbak, L., Krieger, S., Ohlsen, K., Hecker, M., Gerth, U., Ingmer, Hanne & Frees, Dorte, 2013, In: Journal of Proteome Research. 12, 2, p. 547-558 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    60. 2014
    61. Published

      Clp chaperones and proteases are central in stress survival, virulence and antibiotic resistance of Staphylococcus aureus

      Frees, Dorte, Gerth, U. & Ingmer, Hanne, 2014, In: International Journal of Medical Microbiology. 304, 2, p. 142-149 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    62. Published

      Solonamide B inhibits quorum sensing and reduces Staphylococcus aureus mediated killing of human neutrophils

      Nielsen, A., Månsson, M., Bojer, Martin Saxtorph, Gram, L., Larsen, T. O., Novick, R. P., Frees, Dorte, Frøkiær, Hanne & Ingmer, Hanne, 2014, In: P L o S One. 9, 1, p. e84992 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    63. Published

      β-lactam resistance in methicillin-resistant Staphylococcus aureus USA300 is increased by inactivation of the ClpXP protease

      Bæk, K. T., Gründling, A., Mogensen, R. G., Thøgersen, L., Petersen, A., Paulander, W. E. A. & Frees, Dorte, 2014, In: Antimicrobial Agents and Chemotherapy. 58, 8, p. 4593-4603 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    64. 2015
    65. Published

      Antigen uptake in zebrafish

      Jørgensen, Louise von Gersdorff, Mehrdana, Foojan, Kania, Per, Larsen, M. H., Frees, Dorte & Buchmann, Kurt, 2015.

      Research output: Contribution to conference › Conference abstract for conference › Research

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