David E. Gloriam

David E. Gloriam

Professor

ORCID: 0000-0002-4299-7561

Publication year:
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  1. 2021
  2. E-pub ahead of print

    Targeting the APP-Mint2 Protein-Protein Interaction with a Peptide-Based Inhibitor Reduces Amyloid-β Formation

    Bartling, Christian Reinhard Otto, Jensen, T. M. T., Henry, S. M., Colliander, A. L., Sereikaité, Vita, Wenzler, M., Jain, P., Maric, H. M., Harpsøe, Kasper, Pedersen, S. W., Clemmensen, L. S., Haugaard-Kedström, L. M., Gloriam, David E., Ho, A. & Strømgaard, Kristian, 5 Jan 2021, In : Journal of the American Chemical Society.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    GPCRdb in 2021: integrating GPCR sequence, structure and function

    Kooistra, Albert Jelke, Mordalski, S., Pándy-Szekeres, G., Esguerra Neira, Mauricio, Mamyrbekov, Alibek, Munk, Christian, Keserű, G. M. & Gloriam, David E., 2021, In : Nucleic Acids Research. 49, D1, p. D335-D343

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Structure of the class D GPCR Ste2 dimer coupled to two G proteins

    Velazhahan, V., Ma, N., Pandy-Szekeres, G., Kooistra, Albert Jelke, Lee, Y., Gloriam, David E., Vaidehi, N. & Tate, C. G., 2021, In : Nature. 589, p. 148-153 +app 24 pp

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. 2020
  6. Published

    Discovery of a new class of orthosteric antagonists with nanomolar potency at extrasynaptic GABAA receptors

    Falk-Petersen, C. B., Tsonkov, T. M., Nielsen, M. S., Harpsøe, Kasper, Bundgaard, C., Frølund, Bente, Kristiansen, Uffe, Gloriam, David E. & Wellendorph, Petrine, 22 Jun 2020, In : Scientific Reports. 10, 1, 12 p., 10078.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Novel approaches leading towards peptide GPCR de-orphanisation

    Hauser, Alexander Sebastian, Gloriam, David E., Bräuner-Osborne, Hans & Foster, S. R., 1 Mar 2020, In : British Journal of Pharmacology. 177, 5, p. 961-968 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    Combinatorial expression of GPCR isoforms affects signalling and drug responses

    Marti-Solano, M., Crilly, S. E., Malinverni, D., Munk, Christian, Harris, M., Pearce, A., Quon, T., Mackenzie, A. E., Wang, X., Peng, J., Tobin, A. B., Ladds, G., Milligan, G., Gloriam, David E., Puthenveedu, M. A. & Babu, M. M., 2020, In : Nature. 587, p. 650-656 28 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Delineation of molecular determinants for FR900359 inhibition of Gq/11 unlocks inhibition of Gαs

    Boesgaard, M. W., Harpsøe, Kasper, Malmberg, M., Underwood, C. R., Inoue, A., Mathiesen, Jesper M., König, G. M., Kostenis, E., Gloriam, David E. & Bräuner-Osborne, Hans, 2020, In : The Journal of Biological Chemistry. 295, p. 13850-13861

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists

    Zhang, X., Belousoff, M. J., Zhao, P., Kooistra, Albert Jelke, Truong, T. T., Ang, S. Y., Underwood, C. R., Egebjerg, T., Šenel, P., Stewart, G. D., Liang, Y., Glukhova, A., Venugopal, H., Christopoulos, A., Furness, S. G. B., Miller, L. J., Reedtz-Runge, S., Langmead, C. J., Gloriam, David E., Danev, R., Sexton, P. M. & Wootten, D., 2020, In : Molecular Cell. 80, 3, p. 485-500

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    G protein-coupled receptor pharmacology-The next generation

    Bräuner-Osborne, Hans, Rosenkilde, Mette, Gether, Ulrik & Gloriam, David E., 2020, In : Basic & Clinical Pharmacology & Toxicology. 126, Supplement 6, p. 3-4 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  12. Published

    GPCRmd uncovers the dynamics of the 3D-GPCRome

    Rodríguez-Espigares, I., Torrens-Fontanals, M., Tiemann, J. K. S., Aranda-García, D., Ramírez-Anguita, J. M., Stepniewski, T. M., Worp, N., Varela-Rial, A., Morales-Pastor, A., Medel-Lacruz, B., Pándy-Szekeres, G., Mayol, E., Giorgino, T., Carlsson, J., Deupi, X., Filipek, S., Filizola, M., Gómez-Tamayo, J. C., Gonzalez, A., Gutiérrez-de-Terán, H., Jiménez-Rosés, M., Jespers, W., Kapla, J., Khelashvili, G., Kolb, P., Latek, D., Marti-Solano, M., Matricon, P., Matsoukas, M., Miszta, P., Olivella, M., Perez-Benito, L., Provasi, D., Ríos, S., Torrecillas, I. R., Sallander, J., Sztyler, A., Vasile, S., Weinstein, H., Zachariae, U., Hildebrand, P. W., De Fabritiis, G., Sanz, F., Gloriam, David E., Cordomi, A., Guixà-González, R. & Selent, J., 2020, In : Nature Methods. 17, 8, p. 777-787

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 5953796