Christoffer Clemmensen
Associate Professor
Clemmensen Group
Blegdamsvej 3B, Mærsk Tårnet, 6. sal
2200 København N.
Metabolic syndrome and extensive adipose tissue inflammation in morbidly obese Göttingen minipigs
Renner, S., Blutke, A., Dobenecker, B., Dhom, G., Müller, TD., Finan, B., Clemmensen, C., Bernau, M., Novak, I., Rathkolb, B., Senf, S., Zöls, S., Roth, M., Götz, A., M. Hofmann, S., Hrabě de Angelis, M., Wanke, R., Kienzl, E., M. Scholz, A., DiMarchi, R. D. & 3 others, , 2018, In: Molecular Metabolism. 16, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity
Quarta, C., Clemmensen, C., Zhu, Z., Yang, B., Joseph, S. S., Lutter, D., Yi, C-X., Graf, E., García-Cáceres, C., Legutko, B., Fischer, K., Brommage, R., Zizzari, P., Franklin, B. S., Krueger, M., Koch, M., Vettorazzi, S., Li, P., Hofmann, S. M., Bakhti, M. & 16 others, , 3 Oct 2017, In: Cell Metabolism. 26, 4, p. 620-632.e6Research output: Contribution to journal › Journal article › Research › peer-review
Monomeric GLP-1/GIP/glucagon triagonism corrects obesity, hepatosteatosis, and dyslipidemia in female mice
Jall, S., Sachs, S., Clemmensen, Christoffer, Finan, B., Neff, F., DiMarchi, R. D., Tschöp, M. H., Müller, T. D. & Hofmann, S. M., May 2017, In: Molecular Metabolism. 6, 5, p. 440-446 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Muscarinic receptors in energy homeostasis: Physiology and pharmacology
Falk, S., Lund, Camilla & Clemmensen, Christoffer, 2020, In: Basic & Clinical Pharmacology & Toxicology. 126, Suppl. 6, p. 66-76 11 p.Research output: Contribution to journal › Review › Research › peer-review
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Neuronal Blockade of Thyroid Hormone Signaling Increases Sensitivity to Diet-Induced Obesity in Adult Male Mice
Rial-Pensado, E., Canaple, L., Guyot, R., Clemmensen, Christoffer, Wiersema, J., Wu, S., Richard, S., Boelen, A., Müller, T. D., López, M., Flamant, F. & Gauthier, K., 2023, In: Endocrinology. 164, 4Research output: Contribution to journal › Journal article › Research › peer-review
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Novel combinatorial therapies involving leptin: Opportunities for mechanistic advances and therapeutic translation in human diseases
Müller, T. D., Clemmensen, Christoffer, Finan, B., Dimarchi, R. D. & Tschöp, M. H., 1 Jan 2015, Leptin: Regulation and Clinical Applications. Springer, p. 267-279 13 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Outrunning obesity with Lac-Phe?
Lund, Jens, Clemmensen, Christoffer & Schwartz, Thue W., 2022, In: Cell Metabolism. 34, 8, p. 1085-1087 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Overlooked confounding in studies of metabolite salts
Lund, Jens, Clemmensen, Christoffer & Gerhart-Hines, Zach, 2023, In: Nature Metabolism. 5, 4, p. 542-543 2 p.Research output: Contribution to journal › Comment/debate › Research
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Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise
Klein, A. B., Nicolaisen, T. S., Ørtenblad, N., Gejl, K. D., Jensen, R., Fritzen, A. M., Larsen, E. L., Karstoft, K., Poulsen, H. E., Morville, T., Sahl, R. E., Helge, J. W., Lund, J., Falk, S., Lyngbæk, M., Ellingsgaard, H., Pedersen, B. K., Lu, W., Finan, B., Jørgensen, S. B. & 5 others, , 2021, In: Nature Communications. 12, 9 p., 1041.Research output: Contribution to journal › Journal article › Research › peer-review
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Pharmacological targeting of α3β4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity
Jall, S., De Angelis, M., Lundsgaard, Anne-Marie, Fritzen, Andreas Mæchel, Nicolaisen, T. S., Klein, A. B., Novikoff, A., Sachs, S., Richter, Erik A., Kiens, Bente, Schramm, K., Tschöp, M. H., Stemmer, K., Clemmensen, Christoffer, Müller, T. D. & Kleinert, Maximilian, 2020, In: Diabetologia. 63, 6, p. 1236-1247 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Physiological protection against weight gain: evidence from overfeeding studies and future directions
Lund, Jens & Clemmensen, Christoffer, 2023, In: Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 378, 1885, 11 p., 2022.0229.Research output: Contribution to journal › Review › Research › peer-review
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Pirt deficiency has subtle female-specific effects on energy and glucose metabolism in mice
Jall, S., Finan, B., Collden, G., Fischer, K., Dong, X., Tschoep, M. H., Mueller, T. D. & Clemmensen, Christoffer, 2019, In: Molecular Metabolism. 23, p. 75-81Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma Metabolome Profiling of Resistance Exercise and Endurance Exercise in Humans
Morville, T., Sahl, Ronni Eg, Moritz, Thomas, Helge, Jørn Wulff & Clemmensen, Christoffer, 2020, In: Cell Reports. 33, 13, 14 p., 108554.Research output: Contribution to journal › Journal article › Research › peer-review
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Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R
Lund, Camilla, Ranea-Robles, Pablo, Falk, S., Belmont-Rausch, Dylan Matthew, Skovbjerg, G., Vibe-Petersen, V. K., Krauth, Nathalie, Skytte, J. L., Vana, V., Roostalu, U., Pers, Tune H, Lund, Jens & Clemmensen, Christoffer, 2024, In: Nature Communications. 15, 1192.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RANKL regulates testicular cancer growth and Denosumab treatment has suppressive effects on GCNIS and advanced seminoma
Andreassen, C. H., Lorenzen, M., Nielsen, J. E., Kafai Yahyavi, S., Toft, Birgitte Grønkær, Ingerslev, L. R., Clemmensen, Christoffer, Rasmussen, Lene Juel, Bokemeyer, C., Juul, Anders, Jørgensen, A. & Jensen, M. B., 2022, In: British Journal of Cancer. 127, p. 408-421Research output: Contribution to journal › Journal article › Research › peer-review
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ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging
Snieckute, G., Ryder, L., Vind, A. C., Wu, Z., Arendrup, F. S., Stoneley, M., Chamois, S., Martinez-Val, A., Leleu, M., Dreos, R., Russell, A., Gay, D. M., Genzor, A. V., Choi, B. S-Y., Basse, A. L., Sass, F., Dall, M., Dollet, L. C. M., Blasius, M., Willis, A. E. & 10 others, , 2023, In: Science (New York, N.Y.). 382, 6675, 14 p., eadf3208.Research output: Contribution to journal › Journal article › Research › peer-review
Reappraisal of GIP Pharmacology for Metabolic Diseases
Finan, B., Müller, T. D., Clemmensen, Christoffer, Perez-Tilve, D., DiMarchi, R. D. & Tschöp, M. H., May 2016, In: Trends in Molecular Medicine. 22, 5, p. 359-76 18 p.Research output: Contribution to journal › Review › Research › peer-review
Renaissance of leptin for obesity therapy
Quarta, C., Sánchez-Garrido, M. A., Tschöp, M. H. & Clemmensen, Christoffer, May 2016, In: Diabetologia. 59, 5, p. 920-7 8 p.Research output: Contribution to journal › Review › Research › peer-review
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Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response
Snieckute, Goda, Genzor Garbayo, Aitana Victoria, Vind, Anna Constance, Jordan, Laura Ryder, Stoneley, M., Chamois, S., Dreos, R., Nordgaard, C., Sass, Frederike, Blasius, Melanie, López, A. R., Brynjólfsdóttir, S. H., Andersen, Kasper Langebjerg, Willis, A. E., Frankel, Lisa, Poulsen, Steen Seier, Gatfield, D., Gerhart-Hines, Zach, Clemmensen, Christoffer & Bekker-Jensen, Simon Holst, 2022, In: Cell Metabolism. 34, 12, p. 2036-2046.e8 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Robust GLP-1 secretion by basic L-amino acids does not require the GPRC6A receptor
Clemmensen, Christoffer, Jørgensen, C. V., Smajilovic, S. & Bräuner, Hans, 2017, In: Diabetes, Obesity and Metabolism. 19, 4, p. 599-603Research output: Contribution to journal › Journal article › Research › peer-review
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Role of Energy Excretion in Human Body Weight Regulation
Lund, Jens, Gerhart-Hines, Zach & Clemmensen, Christoffer, 2020, In: Trends in Endocrinology and Metabolism. 31, 10, p. 705-708 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Role of sociodemographic, clinical, behavioral, and molecular factors in precision prevention of type 2 diabetes: a systematic review
Bodhini, D., Morton, R. W., Santhakumar, V., Nakabuye, Mariam, Pomares-Millan, H., Clemmensen, Christoffer, Fitzpatrick, S. L., Guasch Ferre, Marta, Pankow, J. S., Ried-Larsen, M., Franks, P. W., Tobias, D. K., Merino, Jordi, Mohan, V., Loos, Ruth & ADA/EASD Precision Medicine in Diabetes Initiative, A. P. M. I. D. I., 2023, medRxiv.Research output: Working paper › Preprint › Research
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Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine
Tobias, D. K., Merino, J., Ahmad, A., Aiken, C., Benham, J. L., Bodhini, D., Clark, A. L., Colclough, K., Corcoy, R., Cromer, S. J., Duan, D., Felton, J. L., Francis, E. C., Gillard, P., Gingras, V., Gaillard, R., Haider, E., Hughes, A., Ikle, J. M., Jacobsen, L. M. & 180 others, , 2023, In: Nature Medicine. 29, 10, p. 2438-2457 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
Fadahunsi, N., Petersen, J. O., Metz, S., Jakobsen, A., Mathiesen, C. V., Buch-Rasmussen, A. S., Kurgan, N. K., Larsen, J. K., Andersen, R. C., Topilko, T., Svendsen, C., Apuschkin, M., Skovbjerg, G., Schmidt, J. H., Houser, G. A., Jager, S. E., Bach, A., Deshmukh, A. S., Kilpeläinen, T. O., Strømgaard, K. & 2 others, , 2024, In: Science Advances. 10, 9, 20 p., eadg2636.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The G protein-coupled receptor, class C, group 6, subtype A (GPRC6A) receptor: from cloning to physiological function
Clemmensen, Christoffer, Smajilovic, S., Wellendorph, Petrine & Bräuner, Hans, 2014, In: British Journal of Pharmacology. 171, 5, p. 1129-1141Research output: Contribution to journal › Journal article › Research › peer-review
ID: 16824492
Most downloads
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316
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GLP-1/glucagon receptor co-agonism for treatment of obesity
Research output: Contribution to journal › Review › Research › peer-review
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250
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Exercise increases circulating GDF15 in humans
Research output: Contribution to journal › Letter › Research › peer-review
Published -
173
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Time-resolved hypothalamic open flow micro-perfusion reveals normal leptin transport across the blood–brain barrier in leptin resistant mice
Research output: Contribution to journal › Letter › Research › peer-review
Published