Birgitte Rahbek Kornum

Birgitte Rahbek Kornum

Guest Researcher, Associate Professor - Promotion Programme


  1. Published

    CHARACTERIZATION OF REGULATORY NETWORKS BY MULTI-OMICS COMBINING PROTEOMICS WITH BULK AND SINGLE-CELL RNA SEQUENCING IN A DIET-INDUCED AND BIOPSY-CONFIRMED MOUSE MODEL OF NON-ALCOHOLIC STEATOHEPATITIS

    AEgidius, H., Veidal, S., Feigh, M., Puglia, M., Hallenborg, P., Vrang, N., Jelsing, J., Kornum, Birgitte Rahbek, Blagoev, B. & Rigbolt, K., 2019, In: Hepatology. 70, Supplement 1, p. 1278A-1279A 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  2. Published

    Pre-treatment of blood samples reveal normal blood hypocretin/orexin signal in narcolepsy type I

    Aegidius, H. M., Kruse, L., Christensen, G. L., Lorentzen, M. P., Jørgensen, Niklas Rye, Moresco, M., Pizza, F., Plazzi, G., Jennum, Poul & Kornum, Birgitte Rahbek, 2021, In: Brain Communications. 3, 2, 13 p., 050.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Unge forskere: S-løftebrud er en katastrofe for universiteterne

    Aguirre, V., Andersen, C., Andersen, P. R., Bjørk, R., Clemmensen, C., Dalsgaard, P., Danbolt, M., Dimke, H., Engberg-Pedersen, A., Feliu, E., Jauffred, L., Jønsson, K., Kornum, B. R., Kropp, K., Laustsen, A., Levisen, C., Lock, N., Lomborg, S., Møller, N. M., Niss, K. & 5 others, Pedersen, B. P., Pristed, B. B., Sørensen, Thomas Just, Ulstrup, S. & Vallgårda, Karen Asta Arnfred, 2019

    Research output: Other contributionCommunication

  4. Published

    Predictors of hypocretin (orexin) deficiency in narcolepsy without cataplexy

    Andlauer, O., Moore, H., Hong, S., Dauvilliers, Y., Kanbayashi, T., Nishino, S., Han, F., Silber, M. H., Rico, T., Einen, M., Kornum, Birgitte Rahbek, Jennum, Poul, Knudsen, S., Nevsimalova, S., Poli, F., Plazzi, G. & Mignot, E., 2012, In: Sleep. 35, 9, p. 1247-55F

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The 5-HT1A serotonin receptor is located on calbindin- and parvalbumin-containing neurons in the rat brain

    Aznar, S., Qian, Z., Shah, R., Kornum, Birgitte Rahbek & Knudsen, Gitte Moos, 3 Jan 2003, In: Brain Research. 959, 1, p. 58-67 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Narcolepsy - clinical spectrum, aetiopathophysiology, diagnosis and treatment

    Bassetti, C. L. A., Adamantidis, A., Burdakov, D., Han, F., Gay, S., Kallweit, U., Khatami, R., Koning, F., Kornum, Birgitte Rahbek, Lammers, G. J., Liblau, R. S., Luppi, P. H., Mayer, G., Pollmaecher, T., Sakurai, T., Sallusto, F., Scammell, T. E., Tafti, M. & Dauvilliers, Y., 2019, In: Nature Reviews. Neurology. 15, 9, p. 519-539

    Research output: Contribution to journalReviewResearchpeer-review

  7. Published

    Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission

    Bentsen, M. A., Rausch, D. M., Mirzadeh, Z., Muta, K., Scarlett, J. M., Brown, J. M., Herranz-Pérez, V., Baquero, A. F., Thompson, J., Alonge, K. M., Faber, C. L., Kaiyala, K. J., Bennett, C., Pyke, C., Ratner, C., Egerod, K. L., Holst, B., Meek, T. H., Kutlu, B., Zhang, Y. & 9 others, Sparso, T., Grove, K. L., Morton, G. J., Kornum, Birgitte Rahbek, García-Verdugo, J. M., Secher, A., Jorgensen, R., Schwartz, M. W. & Pers, Tune H, 2020, In: Nature Communications. 11, 1, 4458.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Production of human entorhinal stellate cell-like cells by forward programming shows an important role of Foxp1 in reprogramming

    Bergmann, T., Liu, Y., Skov, J., Mogus, L., Lee, J., Pfisterer, U., Handfield, L. F., Asenjo-Martinez, A., Lisa-Vargas, I., Seemann, S. E., Lee, J. T. H., Patikas, N., Kornum, B. R., Denham, M., Hyttel, P., Witter, M. P., Gorodkin, J., Pers, T. H., Hemberg, M., Khodosevich, K. & 1 others, Hall, Vanessa Jane, 2022, In: Frontiers in Cell and Developmental Biology. 10, 976549.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Cerebrospinal Fluid Hypocretin-1 (Orexin-A) Level Fluctuates with Season and Correlates with Day Length

    Boddum, K., Hansen, M. H., Jennum, Poul & Kornum, Birgitte Rahbek, 2016, In: PloS one. 11, 3, 13 p., e0151288.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Novel method for evaluation of eye movements in patients with narcolepsy

    Christensen, J. A. E., Kempfner, L., Leonthin, H. L., Hvidtfelt, M., Nikolic, M., Kornum, Birgitte Rahbek & Jennum, Poul, May 2017, In: Sleep Medicine. 33, p. 171-180 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Sleep spindle density in narcolepsy

    Christensen, J. A. E., Nikolic, M., Hvidtfelt, M., Kornum, Birgitte Rahbek & Jennum, Poul, Jun 2017, In: Sleep Medicine. 34, p. 40-49 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    CD4+ T cell autoimmunity to hypocretin/orexin and cross-reactivity to a 2009 H1N1 influenza A epitope in narcolepsy

    De la Herrán-Arita, A. K., Kornum, Birgitte Rahbek, Mahlios, J., Jiang, W., Lin, L., Hou, T., Macaubas, C., Einen, M., Plazzi, G., Crowe, C., Newell, E. W., Davis, M. M., Mellins, E. D. & Mignot, E., 18 Dec 2013, In: Science Translational Medicine. 5, 216, p. 216ra176

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Retraction of the research article: "CD4⁺ T cell autoimmunity to hypocretin/orexin and cross-reactivity to a 2009 H1N1 influenza A epitope in narcolepsy"

    De la Herrán-Arita, A. K., Kornum, Birgitte Rahbek, Mahlios, J., Jiang, W., Lin, L., Hou, T., Macaubas, C., Einen, M., Plazzi, G., Crowe, C., Newell, E. W., Davis, M. M., Mellins, E. D. & Mignot, E., 30 Jul 2014, In: Science Translational Medicine. 6, 247, 247rt1.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Rare missense mutations in P2RY11 in narcolepsy with cataplexy

    Degn, M., Dauvilliers, Y., Dreisig, K., Lopez, R., Pfister, C., Pradervand, S., Kornum, Birgitte Rahbek & Tafti, M., 1 Jun 2017, In: Brain. 140, 6, p. 1657-1668 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Type 1 narcolepsy: a CD8+ T cell-mediated disease?

    Degn, M. & Kornum, Birgitte Rahbek, Sep 2015, In: Annals of the New York Academy of Sciences. 1351, p. 80-88 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Altered surface expression of P2Y11 receptor with narcolepsy-associated mutations

    Dommer, M. W., Dreisig, K. & Kornum, Birgitte Rahbek, 2019, In: Pharmacological Reports. 71, 5, p. 926-928 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Validation of antibodies for neuroanatomical localization of the P2Y receptor in macaque brain

    Dreisig, K., Degn, M., Sund, L., Hadaczek, P., Samaranch, L., San Sebastian, W., Bankiewicz, K. & Kornum, Birgitte Rahbek, Dec 2016, In: Journal of Chemical Neuroanatomy. 78, p. 25-33 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Human P2Y11 expression level affects human P2X7 receptor-mediated cell death

    Dreisig, K., Sund, L., Dommer, M. W., Kristensen, N. P., Boddum, K., Viste, R., Fredholm, S., Ødum, Niels, Jäättelä, M., Skov, Søren & Kornum, Birgitte Rahbek, 2018, In: Frontiers in Immunology. 9, JUN, 12 p., 1159.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    A critical look at the function of the P2Y11 receptor

    Dreisig, K. & Kornum, Birgitte Rahbek, Sep 2016, In: Purinergic Signalling. 12, 3, p. 427-37 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  20. N-terminal tagging of human P2X7 receptor disturbs calcium influx and dye uptake

    Dreisig, K., Kristensen, N. P., Dommer, M. W., Jørgensen, N. R. & Kornum, Birgitte Rahbek, 2018, In: Purinergic Signalling. 14, 1, p. 83-90 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    An approach for serotonin depletion in pigs: effects on serotonin receptor binding

    Ettrup, A., Kornum, Birgitte Rahbek, Weikop, P. & Knudsen, Gitte Moos, 2011, In: Synapse. 65, 2, p. 136-45 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Radiosynthesis and evaluation of 11C-CIMBI-5 as a 5-HT2A receptor agonist radioligand for PET

    Ettrup, A., Palner, M., Gillings, N., Santini, M. A., Hansen, M., Kornum, Birgitte Rahbek, Rasmussen, L. K., Någren, K., Madsen, J., Begtrup, M. & Knudsen, Gitte Moos, 1 Nov 2010, In: Journal of Nuclear Medicine. 51, 11, p. 1763-1770

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    ImmunoChip Study Implicates Antigen Presentation to T Cells in Narcolepsy

    Faraco, J., Lin, L., Kornum, B. R., Kenny, E. E., Trynka, G., Einen, M., Rico, T. J., Lichtner, P., Dauvilliers, Y., Arnulf, I., Lecendreux, M., Javidi, S., Geisler, P., Mayer, G., Pizza, F., Poli, F., Plazzi, G., Overeem, S., Lammers, G. J., Kemlink, D. & 28 others, Sonka, K., Nevsimalova, S., Rouleau, G., Desautels, A., Montplaisir, J., Frauscher, B., Ehrmann, L., Högl, B., Jennum, Poul, Bourgin, P., Peraita-Adrados, R., Iranzo, A., Bassetti, C., Chen, W., Concannon, P., Thompson, S. D., Damotte, V., Fontaine, B., Breban, M., Gieger, C., Klopp, N., Deloukas, P., Wijmenga, C., Hallmayer, J., Onengut-Gumuscu, S., Rich, S. S., Winkelmann, J. & Mignot, E., 2013, In: P L o S Genetics (Online). 9, 2, 7 p., e1003270.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published
  25. Published

    Hjernens regulering af søvn

    Gammeltoft, S., Nordvang, A. H. & Kornum, Birgitte Rahbek, 2013, Søvn. Jennum, P. (ed.). 1 ed. København: Munksgaard , p. 39-50 12 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  26. Published

    Neurobasal media facilitates increased specificity of siRNA-mediated knockdown in primary cerebellar cultures

    Gustafsson, J. R., Katsioudi, G., Issazadeh-Navikas, Shohreh & Kornum, Birgitte Rahbek, 1 Dec 2016, In: Journal of Neuroscience Methods. 274, p. 116-124 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    DNMT1 regulates expression of MHC class I in post-mitotic neurons

    Gustafsson, J. R., Katsioudi, G., Degn, M., Ejlerskov, P., Issazadeh-Navikas, Shohreh & Kornum, Birgitte Rahbek, 2018, In: Molecular Brain. 11, 1, p. 1-16 16 p., 36.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Sleep-wake stability in narcolepsy patients with normal, low and unmeasurable hypocretin levels

    Hansen, M. H., Kornum, Birgitte Rahbek & Jennum, Poul, Jun 2017, In: Sleep Medicine. 34, p. 1-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Meningeal Lymphangiogenesis and Enhanced Glymphatic Activity in Mice with Chronically Implanted EEG Electrodes

    Hauglund, Natalie Linea, Kusk, P., Kornum, Birgitte Rahbek & Nedergaard, Maiken, 2020, In: Journal of Neuroscience. 40, 11, p. 2371-2380 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    The evolutionary conserved microrna MIR-137 regulates gene expression and diurnal rhythm of the wake-promoting hypocretin neuropeptides

    Holm, A., Moseholm, Kristine Frøsig, Justinussen, Jessica, Silahtaroglu, Asli, Adamantidis, A. & Kornum, Birgitte Rahbek, 2017, In: Sleep Medicine. 40, Supplement 1, p. E132-E133 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  31. Published

    The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin/orexin and modulates the wake to sleep ratio

    Holm, A., Possovre, M. L., Bandarabadi, M., Moseholm, Kristine Frøsig, Justinussen, Jessica, Bozic, I., Lemcke, René, Arribat, Y., Amati, F., Silahtaroglu, Asli, Juventin, M., Adamantidis, A., Tafti, M. & Kornum, Birgitte Rahbek, 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 17, 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    miRNA profiles in plasma from patients with sleep disorders reveal dysregulation of miRNAs in narcolepsy and other central hypersomnias

    Holm, A., Bang-Berthelsen, C. H., Knudsen, S., Kornum, Birgitte Rahbek, Modvig, S., Jennum, Poul & Gammeltoft, S., Sep 2014, In: Sleep. 37, 9, p. 1525-1533 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    EIF3G is associated with narcolepsy across ethnicities

    Holm, A., Lin, L., Faraco, J., Mostafavi, S., Battle, A., Zhu, X., Levinson, D. F., Han, F., Gammeltoft, S., Jennum, Poul, Mignot, E. & Kornum, Birgitte Rahbek, 2015, In: European Journal of Human Genetics. 23, 11, p. 1573-80 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    miRNA profiles in cerebrospinal fluid from patients with central hypersomnias

    Holm, A., Bang-Berthelsen, C. H., Knudsen, S., Modvig, S., Kornum, Birgitte Rahbek, Gammeltoft, S. & Jennum, Poul, 15 Dec 2014, In: Journal of the Neurological Sciences. 347, 1-2, p. 199-204 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Monozygotic twins discordant for narcolepsy type 1 and multiple sclerosis

    Jennum, Poul, Kornum, Birgitte Rahbek, Issa, N. M., Gammeltoft, S., Tommerup, Niels, Morling, Niels, Tümer, Asuman Zeynep & Knudsen, S., Aug 2016, In: Neurology: Neuroimmunology & Neuroinflammation. 3, 4, 2 p., e249.

    Research output: Contribution to journalLetterResearchpeer-review

  36. Published

    In vivo clonal expansion and phenotypes of hypocretin-specific CD4+ T cells in narcolepsy patients and controls

    Jiang, W., Birtley, J. R., Hung, S. C., Wang, W., Chiou, S. H., Macaubas, C., Kornum, Birgitte Rahbek, Tian, L., Huang, H., Adler, L., Weaver, G., Lu, L., Ilstad-Minnihan, A., Somasundaram, S., Ayyangar, S., Davis, M. M., Stern, L. J. & Mellins, E. D., 2019, In: Nature Communications. 10, 1, 17 p., 5247.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    An optimized method for measuring hypocretin-1 peptide in the mouse brain reveals differential circadian regulation of hypocretin-1 levels rostral and caudal to the hypothalamus

    Justinussen, Jessica, Holm, A. & Kornum, Birgitte Rahbek, 2015, In: Neuroscience. 310, p. 354-361 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    How hypocretin agonists may improve the quality of wake in narcolepsy

    Justinussen, Jessica, Jensen, Christine Egebjerg & Kornum, Birgitte Rahbek, 2023, In: Trends in Molecular Medicine. 29, 1, p. 61-69 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  39. Published

    Cerebrospinal Fluid Biomarkers of Neurodegeneration Are Decreased or Normal in Narcolepsy

    Jennum, Poul, Østergaard Pedersen, L., Czarna Bahl, J. M., Modvig, S., Fog, K., Holm, A., Kornum, Birgitte Rahbek & Gammeltoft, S., 1 Jan 2017, In: Sleep. 40, 1, 9 p., zsw006.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    The European Narcolepsy Network (EU-NN) database

    Khatami, R., Luca, G., Baumann, C. R., Bassetti, C. L., Bruni, O., Canellas, F., Dauvilliers, Y., Del Rio-Villegas, R., Feketeova, E., Ferri, R., Geisler, P., Högl, B., Jennum, P., Kornum, B. R., Lecendreux, M., Martins-da-Silva, A., Mathis, J., Mayer, G., Paiva, T., Partinen, M. & 11 others, Peraita Adrados, R., Plazzi, G., Santamaria, J., Sonka, K., Riha, R., Tafti, M., Wierzbicka, A., Young, P., Lammers, G. J., Overeem, S. & European Narcolepsy Network, E. N. N., Jun 2016, In: Journal of Sleep Research. 25, 3, p. 356-64 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Attenuation and scatter correction in myocardial SPET: improved diagnostic accuracy in patients with suspected coronary artery disease.

    Kjaer, A., Cortsen, A., Kornum, Birgitte Rahbek, Hasseldam, Henrik & Hesse, B., 2002, In: European Journal of Nuclear Medicine and Molecular Imaging. 29, 11, p. 1438-42 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Early IVIg treatment has no effect on post-H1N1 narcolepsy phenotype or hypocretin deficiency

    Knudsen, S., Biering-Sørensen, B., Kornum, Birgitte Rahbek, Petersen, E., Ibsen, J. D., Gammeltoft, S., Mignot, E. & Jennum, Poul, 2012, In: Neurology. 79, 1, p. 102-3 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Experimental sickness reduces hypocretin receptor 1 expression in the lateral hypothalamus and ventral tegmental area of female mice

    Pedersen, Mie Gunni Kolmos, Pérez Arribas, Alba, Kornum, Birgitte Rahbek & Justinussen, Jessica, 2023, In: European Journal of Neuroscience. 58, 9, p. 4002-4010 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Narcolepsy

    Kornum, Birgitte Rahbek, Knudsen, S., Ollila, H. M., Pizza, F., Jennum, Poul, Dauvilliers, Y. & Overeem, S., 2017, In: Nature Reviews. Disease Primers. 3, 19 p., 16100.

    Research output: Contribution to journalReviewResearchpeer-review

  45. Published

    Adeno-associated viral vector serotypes 1 and 5 targeted to the neonatal rat and pig striatum induce widespread transgene expression in the forebrain

    Kornum, Birgitte Rahbek, Stott, S. R. W., Mattsson, B., Wisman, L., Ettrup, A., Hermening, S., Knudsen, Gitte Moos & Kirik, D., 1 Mar 2010, In: Experimental Neurology. 222, 1, p. 70-85 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Serotonin depletion results in a decrease of the neuronal activation caused by rivastigmine in the rat hippocampus

    Kornum, Birgitte Rahbek, Weikop, Pia, Moller, A., Ronn, L. C. B., Knudsen, Gitte Moos & Aznar, S., 16 Feb 2006, In: Brain Research. 1073-1074, p. 262-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Cognitive testing of pigs (Sus scrofa) in translational biobehavioral research

    Kornum, Birgitte Rahbek & Knudsen, Gitte Moos, 2011, In: Neuroscience & Biobehavioral Reviews. 35, 3, p. 437-51 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Evaluation of the novel 5-HT4 receptor PET ligand [11C]SB207145 in the Göttingen minipig

    Kornum, Birgitte Rahbek, Lind, N. M., Gillings, N., Marner, Lisbeth, Andersen, F. & Knudsen, Gitte Moos, 1 Jan 2009, In: Journal of Cerebral Blood Flow and Metabolism. 29, 1, p. 186-96 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Common variants in P2RY11 are associated with narcolepsy

    Kornum, B. R., Kawashima, M., Faraco, J., Lin, L., Rico, T. J., Hesselson, S., Axtell, R. C., Kuipers, H., Weiner, K., Hamacher, A., Kassack, M. U., Han, F., Knudsen, S., Li, J., Dong, X., Winkelmann, J., Plazzi, G., Nevsimalova, S., Hong, S-C., Honda, Y. & 30 others, Honda, M., Högl, B., Ton, T. G. N., Montplaisir, J., Bourgin, P., Kemlink, D., Huang, Y., Warby, S., Einen, M., Eshragh, J. L., Miyagawa, T., Desautels, A., Ruppert, E., Hesla, P. E., Poli, F., Pizza, F., Frauscher, B., Jeong, J., Lee, S., Strohl, K. P., Longstreth, W. T., Kvale, M., Dobrovolna, M., Ohayon, M. M., Nepom, G. T., Wichmann, H., Rouleau, G. A., Gieger, C., Levinson, D. F. & Jennum, Poul, Jan 2011, In: Nature Genetics. 43, 1, p. 66-71 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Narcolepsy type 1: What have we learned from immunology?

    Kornum, Birgitte Rahbek, 2020, In: Sleep. 43, 10, zsaa055.

    Research output: Contribution to journalReviewResearchpeer-review

Previous 1 2 3 Next

ID: 143987587