Birgitte Holst

Birgitte Holst

Guest Researcher


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26 - 50 out of 132Page size: 25
  1. 2019
  2. Published

    The Lysine Demethylase KDM5B Regulates Islet Function and Glucose Homeostasis

    Backe, M. B., Jin, C., Andreone, L., Sankar, A., Agger, K., Helin, K., Madsen, A. N., Poulsen, Steen Seier, Bysani, M., Bacos, K., Ling, C., Javier Perone, M., Holst, Birgitte & Mandrup-Poulsen, Thomas, 2019, In: Journal of Diabetes Research. 2019, 15 p., 5451038.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine

    Deshmukh, A. S., Peijs, L., Beaudry, J. L., Jespersen, N. Z., Nielsen, C. H., Ma, T., Brunner, A. D., Larsen, T. J., Bayarri-Olmos, R., Prabhakar, B. S., Helgstrand, C., Severinsen, M. C. K., Holst, B., Kjaer, A., Tang-Christensen, M., Sanfridson, A., Garred, P., Privé, G. G., Pedersen, B. K., Gerhart-Hines, Z. & 4 others, Nielsen, S., Drucker, D. J., Mann, Matthias & Schéele, Camilla Charlotte Nielsen, 2019, In: Cell Metabolism. 30, 5, p. 963-975.e7 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    ADAMTS9 regulates skeletal muscle insulin sensitivity through extracellular matrix alterations

    Graae, A-S., Grarup, N., Ribel-Madsen, R., Lystbæk, S. H., Boesgaard, T., Staiger, H., Fritsche, A., Wellner, N., Sulek, K., Kjølby, M. F., Backe, M. B., Chubanava, S., Prats, C., Serup, A. K. L., Birk, J. B., Dubail, J., Gillberg, L., Vienberg, S. G., Nykjær, A., Kiens, B. & 10 others, Wojtaszewski, Jørgen F P, Larsen, Steen, Apte, S. S., Häring, H., Vaag, A., Zethelius, B., Pedersen, Oluf Borbye, Treebak, Jonas Thue, Hansen, Torben & Holst, Birgitte, 2019, In: Diabetes. 68, 3, p. 502-514

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Impaired glucose metabolism and altered gut microbiome despite calorie restriction of ob/ob mice

    Kashani, A., Brejnrod, A. D., Jin, C., Kern, T., Madsen, A. N., Holm, L. A., Gerber, G. K., Holm, Jens-Christian, Hansen, Torben, Holst, Birgitte & Arumugam, Mani, 2019, In: Animal Microbiome. 1, 1, 16 p., 11.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Long-Acting Neurotensin Synergizes With Liraglutide to Reverse Obesity Through a Melanocortin-Dependent Pathway

    Ratner, C., He, Z., Grunddal, Kaare Villum, Skov, Louise Julie, Hartmann, Bolette, Zhang, F., Feuchtinger, A., Bjerregaard, Anette, Christoffersen, Christina, Tschöp, M. H., Finan, B., DiMarchi, R. D., Leinninger, G. M., Williams, K. W., Clemmensen, Christoffer & Holst, Birgitte, 2019, In: Diabetes. 68, 6, p. 1329-1340

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Ghrelin-mediated improvements in the metabolic phenotype in the R6/2 mouse model of Huntington's disease

    Rudenko, Olga, Springer, C., Skov, Louise Julie, Madsen, A. N., Hasholt, Lis Frydenreich, Nørremølle, Anne & Holst, Birgitte, 2019, In: Journal of Neuroendocrinology. 31, 7 (SI), 14 p., e12699.

    Research output: Contribution to journal › Conference article › Research › peer-review

  8. Published

    RhoA in tyrosine hydroxylase neurons regulates food intake and body weight via altered sensitivity to peripheral hormones

    Skov, Louise Julie, Ratner, C., Hansen, Nikolaj Winther, Thompson, J. J., Egerod, Kristoffer Lihme, Burm, Hayley Beth, Dalbøge, L. S., Hedegaard, M. A., Brakebusch, Cord Herbert, Pers, Tune H, Perrier, Jean-Francois Marie & Holst, Birgitte, 2019, In: Journal of Neuroendocrinology. 31, 7, 13 p., UNSP e12761.

    Research output: Contribution to journal › Conference article › Research › peer-review

  9. 2018
  10. Published

    The Apolipoprotein M/S1P Axis Controls Triglyceride Metabolism and Brown Fat Activity

    Christoffersen, Christina, Federspiel, C. K., Borup, A., Christensen, P. M., Madsen, A. N., Heine, M., Nielsen, C. H., Kjaer, A., Holst, Birgitte, Heeren, J. & Nielsen, L. B., 2 Jan 2018, In: Cell Reports. 22, 1, p. 175-188

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Hepatic NAD+ levels and NAMPT abundance are unaffected during prolonged high-fat diet consumption in C57BL/6JBomTac mice

    Dall, M., Penke, M., Sulek, K., Matz-Soja, M., Holst, Birgitte, Garten, A., Kiess, W. & Treebak, Jonas Thue, 2018, In: Molecular and Cellular Endocrinology. 473, p. 245-256 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Development of potent and proteolytically stable human neuromedin U receptor agonists

    De Prins, A., Martin, C., Van Wanseele, Y., Skov, Louise Julie, Tömböly, C., Tourwé, D., Caveliers, V., Van Eeckhaut, A., Holst, Birgitte, Rosenkilde, Mette, Smolders, I. & Ballet, S., 20 Jan 2018, In: European Journal of Medicinal Chemistry. 144, p. 887-897 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Synthesis and in Vitro Evaluation of Stabilized and Selective Neuromedin U-1 Receptor Agonists

    De Prins, A., Martin, C., Van Wanseele, Y., Tömböly, C., Tourwé, D., Caveliers, V., Holst, Birgitte, Van Eeckhaut, A., Rosenkilde, M. M., Smolders, I. & Ballet, S., 10 May 2018, In: ACS Medicinal Chemistry Letters. 9, 5, p. 496-501 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    An adult-based insulin resistance genetic risk score associates with insulin resistance, metabolic traits and altered fat distribution in Danish children and adolescents who are overweight or obese

    Graae, A. S., Hollensted, M., Kloppenborg, J. T., Mahendran, Y., Schnurr, T. M., Appel, E. V. R., Rask, J., Nielsen, T. R. H., Johansen, M., Linneberg, Allan René, Jørgensen, M. E., Grarup, Niels, Kadarmideen, H. N., Holst, Birgitte, Pedersen, Oluf Borbye, Holm, Jens-Christian & Hansen, Torben, Aug 2018, In: Diabetologia. 61, 8, p. 1769-1779

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Translating biased signaling in the ghrelin receptor system into differential in vivo functions

    Mende, F., Johnsen, Cecilie Hundahl, Plouffe, B., Skov, Louise Julie, Sivertsen, B., Madsen, A. N., Lückmann, Michael, Diep, T. A., Offermanns, S., Frimurer, Thomas Michael, Bouvier, M. & Holst, Birgitte, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 43, p. E10255-E10264 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2017
  17. Published

    Ghrelin-mediated inhibition of the TSH-stimulated function of differentiated human thyrocytes ex vivo

    Barington, M., Brorson, M. M., Hofman-Bang, J., Rasmussen, Å. K., Holst, Birgitte & Feldt-Rasmussen, Ulla, 2017, In: PloS one. 12, 9, 13 p., e0184992.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Pannexin-2-deficiency sensitizes pancreatic beta-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo

    Berchtold, L. A., Miani, M., Diep, T. A., Madsen, A. N., Cigliola, V., Colli, M., Miskovic Krivokapic, Jelena, Pociot, Flemming, Eizirik, D. L., Meda, P., Holst, Birgitte, Billestrup, Nils & Storling, J., 2017, In: Molecular and Cellular Endocrinology. 448, p. 108-121 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Model-Based Discovery of Synthetic Agonists for the Zn2+-Sensing G-Protein-Coupled Receptor 39 (GPR39) Reveals Novel Biological Functions.

    Frimurer, Thomas Michael, Mende, F., Graae, A., Engelstoft, M. S., Egerod, Kristoffer Lihme, Nygaard, R., Gerlach, L., Hansen, J. B., Schwartz, Thue W. & Holst, Birgitte, 2017, In: Journal of Medicinal Chemistry. 60, 3, p. 886-898 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Exploring the Behavioral and Metabolic Phenotype Generated by Re-Introduction of the Ghrelin Receptor in the Ventral Tegmental Area

    Skov, Louise Julie, Jensen, M., Christiansen, S. H., Ratner, C., Woldbye, David Paul Drucker & Holst, Birgitte, 26 Apr 2017, In: International Journal of Molecular Sciences. 18, 5, 17 p., 914.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. 2016
  22. Published

    GPR119 - a major Enteroendocrine Sensor of Dietary Triglyceride Metabolites Co-acting in Synergy with FFA1 (GPR40)

    Ekberg, J. H., Pedersen, M. H., Kristensen, L. V., Madsen, A. N., Engelstoft, M. S., Husted, Anna Sofie, Sichlau, R., Egerod, Kristoffer Lihme, Timshel, P., Kowalski, T. J., Gribble, F. M., Reiman, F., Hansen, Harald S., Howard, A. D., Holst, Birgitte & Schwartz, Thue W., 25 Oct 2016, In: Endocrinology. 157, 12, p. 4561-4569 9 p., en20161334.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Neurotensin Is Co-Expressed, Co-Released And Acts Together With Glp-1 And Pyy In Enteroendocrine Control Of Metabolism

    Grunddal, Kaare Villum, Ratner, C. F., Svendsen, B., Sommer, F., Engelstoft, M. S., Madsen, A. N., Pedersen, Jens, Nøhr, M. K., Egerod, Kristoffer Lihme, Nawrocki, A. R., Kowalski, T., Howard, A. D., Poulsen, Steen Seier, Offermanns, S., Bäckhed, G. F., Holst, Jens Juul, Holst, Birgitte & Schwartz, Thue W., Jan 2016, In: Endocrinology. 157, 1, p. 176-94 19 p., en20151600.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Anxiolytic-Like Effects of Increased Ghrelin Receptor Signaling in the Amygdala

    Jensen, M., Ratner, C., Rudenko, Olga, Christiansen, S. H., Skov, Louise Julie, Johnsen, Cecilie Hundahl, Woldbye, David Paul Drucker & Holst, Birgitte, 1 May 2016, In: International Journal of Neuropsychopharmacology. 19, 5, 12 p., pyv123.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    C4.4A gene ablation is compatible with normal epidermal development and causes modest overt phenotypes

    Kriegbaum, M. C., Jacobsen, B., Fuchtbauer, A., Hansen, Gert Helge, Christensen, I. J., Friis, Carsten, Persson, M., Engelholm, Lars Henning, Madsen, A. N., Di Meo, I., Lund, I. K., Holst, Birgitte, Kjær, Andreas, Laerum, O. D., Fuchtbauer, E. & Ploug, Michael, 12 May 2016, In: Scientific Reports. 6, 25833.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    In Silico Investigation of the Neurotensin Receptor 1 Binding Site: Overlapping Binding Modes for Small Molecule Antagonists and the Endogenous Peptide Agonist

    Lückmann, Michael, Holst, Birgitte, Schwartz, Thue W. & Frimurer, Thomas Michael, 2016, In: Molecular Informatics. 35, p. 19-24 6 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  27. Published

    Immune malfunction in the GPR39 zinc receptor of knockout mice: Its relationship to depressive disorder

    Młyniec, K., Trojan, E., Ślusarczyk, J., Głombik, K., Basta-Kaim, A., Budziszewska, B., Skrzeszewski, J., Siwek, A., Holst, Birgitte & Nowak, G., 15 Feb 2016, In: Journal of Neuroimmunology. 291, p. 11-17 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Short-term effects of dietary advanced glycation end products in rats

    Poulsen, M. W., Andersen, J. M., Hedegaard, R. S. V., Madsen, A. N., Krath, B. N., Monosik, R., Bak, M. J., Nielsen, J., Holst, Birgitte, Skibsted, Leif Horsfelt, Larsen, L. H. & Dragsted, Lars Ove, 2016, In: British Journal of Nutrition. 115, 4, p. 629-636 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Effects of Peripheral Neurotensin on Appetite Regulation and Its Role in Gastric Bypass Surgery

    Ratner, C., Skov, Louise Julie, Raida, Z., Bächler, T., Bellmann-Sickert, K., Le Foll, C., Sivertsen, B., Dalbøge, L. S., Hartmann, Bolette, Beck-Sickinger, A. G., Madsen, A. N., Jelsing, J., Holst, Jens Juul, Lutz, T. A., Andrews, Z. B. & Holst, Birgitte, Sep 2016, In: Endocrinology. 157, 9, p. 3482-92 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 9886