Bente Frølund

Bente Frølund

Associate Professor


  1. 2020
  2. Published

    Discovery of a new class of orthosteric antagonists with nanomolar potency at extrasynaptic GABAA receptors

    Falk-Petersen, Christina Birkedahl, Tsonkov, T. M., Nielsen, M. S., Harpsøe, Kasper, Bundgaard, C., Frølund, Bente, Kristiansen, Uffe, Gloriam, David E. & Wellendorph, Petrine, 22 Jun 2020, In : Scientific Reports. 10, 1, 12 p., 10078.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Compounds for the treatment of acute brain injury

    Klein, Anders Bue, Leurs, U., Houlton, J., Clausen, Rasmus Prætorius, Frølund, Bente, Clarkson, A. & Wellendorph, Petrine, 2020, Priority No. PCT/DK2019/050041

    Research output: Patent

  4. Published

    Exploring the molecular determinants for subtype-selectivity of 2-amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid analogs as betaine/GABA transporter 1 (BGT1) substrate-inhibitors

    Kickinger, S., Al-Khawaja, A., Haugaard, A. S., Lie, Maria Elena Klibo, Bavo, Francesco, Loeffler, R., Damgaard, M., Ecker, G. F., Frølund, Bente & Wellendorph, Petrine, 2020, In : Scientific Reports. 10, 1, 15 p., 12992.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. E-pub ahead of print

    Radiolabeled HOCPCA as a highly useful tool in drug discovery and pharmacology

    Griem-Krey, Nane, Frølund, Bente, Marek, A. & Wellendorph, Petrine, 2020, In : Journal of Labelled Compounds and Radiopharmaceuticals. 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Sex-specific alterations in GABA receptor-mediated responses in laterodorsal tegmentum (LDT) are associated with prenatal exposure to nicotine

    Eliasen, J. N., Krall, J., Frølund, Bente & Kohlmeier, Kristi Anne, 2020, In : Developmental Neurobiology. 80, 5-6, p. 178-199

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Silencing of spontaneous activity at α4β1/3δ GABAA receptors in hippocampal granule cells reveals different ligand pharmacology

    Dalby, N. O., Falk-Petersen, Christina Birkedahl, Leurs, U., Scholze, P., Krall, J., Frølund, Bente & Wellendorph, Petrine, 2020, In : British Journal of Pharmacology. 177, 17, p. 3975-3990

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Unraveling the Molecular Determinants for GABA Transporter Subtype Selectivity

    Kickinger, S., Al-Khawaja, A., Haugaard, A. S., Lie, Maria Elena Klibo, Bavo, Francesco, Loffler, R., Damgaard, M., Frølund, Bente, Ecker, G. F. & Wellendorph, Petrine, 2020, p. 130A-130A.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  9. 2019
  10. Published

    Five-membered N-heterocyclic Scaffolds as Novel Amino Bioisosteres at gamma-Aminobutyric Acid (GABA) Type A Receptors and GABA Transporters

    Giraudo, A., Krall, J., Bavo, F., Nielsen, Birgitte, Kongstad, Kenneth Thermann, Rolando, B., De Blasio, R., Gloriam, David E., Löffler, R., Thiesen, L., Harpsøe, Kasper, Frydenvang, Karla Andrea, Boschi, D., Wellendorph, Petrine, Lolli, M. L., Jensen, Anders A. & Frølund, Bente, 27 Jun 2019, In : Journal of Medicinal Chemistry. 62, 12, p. 5797-5809

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Synthesis and Pharmacological Evaluation of [C-11]4-Methoxy-N-[2-(thiophen-2-yl) imidazo[1,2-a] pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the delta-Subunit-Containing gamma-Aminobutyric Acid Type A Receptors

    L'Estrade, E. T., Hansen, H. D., Falk-Petersen, Christina Birkedahl, Haugaard, A., Griem-Krey, Nane, Jung, S., Lueddens, H., Schirmeister, T., Erlandsson, M., Ohlsson, T., Knudsen, Gitte Moos, Herth, Matthias Manfred, Wellendorph, Petrine & Frølund, Bente, May 2019, In : ACS Omega. 4, 5, p. 8846-8851

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Lack of evidence for synaptic high-affinity γ-hydroxybutyric acid (GHB) transport in rat brain synaptosomes and 11 Na+ -dependent SLC neurotransmitter transporters

    Thiesen, L., Frølund, Bente & Wellendorph, Petrine, Apr 2019, In : Journal of Neurochemistry. 149, 2, p. 195-210 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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