Lene Jørgensen
Associate Professor
- 2021
- Published
Screening of novel excipients for freeze-dried protein formulations
Holm, T. P., Meng-Lund, H., Rantanen, Jukka, Jørgensen, Lene & Grohganz, Holger, 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 160, p. 55-64 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Protein adsorption to poly(tetrafluoroethylene) membranes modified with grafted poly(acrylic acid) chains
Mohd Hidzir, N., Anitha, A., Kepa, K., Hill, D. J. T., Jørgensen, Lene & Grondahl, L., 2020, In: Biointerphases. 15, 3, 11 p., 031011.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Exploring the chemical space for freeze-drying excipients
Meng-Lund, H., Holm, T. P., Poso, A., Jørgensen, Lene, Rantanen, Jukka & Grohganz, Holger, 2019, In: International Journal of Pharmaceutics. 566, p. 254-263 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Investigation on Secondary Structure Perturbations of Proteins Embedded in Solid Lipid Matrices as a Novel Indicator of their Biological Activity upon In Vitro Release
Zeeshan, F., Tabbassum, M., Jørgensen, Lene & Medlicott, N. J., 1 Feb 2018, In: AAPS PharmSciTech. 19, 2, p. 769–782Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Attenuated Total Reflection Fourier Transform Infrared (ATR FT-IR) Spectroscopy as an Analytical Method to Investigate the Secondary Structure of a Model Protein Embedded in Solid Lipid Matrices
Zeeshan, F., Tabbassum, M., Jørgensen, Lene & Medlicott, N. J., 2018, In: Applied Spectroscopy. 72, 2, p. 268-279 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fluorophore labeling of a cell-penetrating peptide significantly alters the mode and degree of biomembrane interaction
Hedegaard, S. F., Derbas, M. S., Lind, T. K., Kasimova, M. R., Christensen, M. V., Michaelsen, M. H., Campbell, R. A., Jørgensen, Lene, Franzyk, Henrik, Cárdenas, M. & Nielsen, Hanne Mørck, 2018, In: Scientific Reports. 8, 1, 14 p., 6327.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Correlation between calculated molecular descriptors of excipient amino acids and experimentally observed thermal stability of lysozyme
Meng-Lund, H., Friis, N., van de Weert, Marco, Rantanen, Jukka, Poso, A., Grohganz, Holger & Jørgensen, Lene, 15 May 2017, In: International Journal of Pharmaceutics. 523, 1, p. 238-245 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Surface area, volume and shape descriptors as a novel tool for polymer lead design and discovery
Christensen, J. R., Meng-Lund, H., Grohganz, Holger, Poso, A., Laitinen, T., Korhonen, O., Jørgensen, Lene & Pajander, J., 1 May 2017, In: European Journal of Pharmaceutical Sciences. 102, p. 188-195 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Screening of plants used in the European traditional medicine to treat memory disorders for acetylcholinesterase inhibitory activity and anti amyloidogenic activity
Lobbens, E. S. B., Vissing, K. J., Jørgensen, Lene, van de Weert, Marco & Jäger, A. K., 22 Mar 2017, In: Journal of Ethnopharmacology. 200, p. 66-73 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Screening of formulation parameters for stabilizing recombinant human serum albumin (rHSA) in liquid formulations
Baldursdottir, S., Tauhaybeche, M., Pekka Pajander, J., Bukrinski, J. T. & Jørgensen, Lene, Aug 2016, In: Journal of Drug Delivery Science and Technology. 34, p. 1-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanistic study of the inhibitory activity of Geum urbanum extract against α-Synuclein fibrillation
Lobbens, E. S., Breydo, L., Pedersen, T. S., Vestergaard, Bente, Jäger, A. K., Jørgensen, Lene, Uversky, V. & van de Weert, Marco, 21 Jun 2016, In: B B A - Proteins and Proteomics. 1864, 9, p. 1160-1169 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Inhibitory Effect of Natural Products on Protein Fibrillation May Be Caused by Degradation Products – A Study Using Aloin and Insulin
Lobbens, E. S., Foderà, Vito, Nyberg, N., Andersen, K., Jäger, A. K., Jørgensen, Lene & van de Weert, Marco, 16 Feb 2016, In: PloS one. 11, 2, p. 1-16 16 p., e0149148.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipidation effect on surface adsorption and associated fibrillation of the model protein insulin
Hedegaard, S. C. F., Cardenas Gomez, M., Barker, R., Jørgensen, Lene & van de Weert, Marco, 2016, In: Langmuir. 32, 28, p. 7241–7249 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Simple measurements for prediction of drug release from polymer matrices - Solubility parameters and intrinsic viscosity
Madsen, C. G., Skov, A., Baldursdottir, S., Rades, Thomas, Jørgensen, Lene & Medlicott, N. J., 7 Feb 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 92, p. 1-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Competitive adsorption of monoclonal antibodies and nonionic surfactants at solid hydrophobic surfaces
Kapp, S. J., Larsson, I., van de Weert, Marco, Cardenas Gomez, M. & Jørgensen, Lene, 2015, In: Journal of Pharmaceutical Sciences. 104, 2, p. 593-601 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Erratum: Kapp SJ, Larsson I, Van De Weert M, Ćardenas M, Jorgensen L. 2015. Competitive Adsorption of Monoclonal Antibodies and Nonionic Surfactants at Solid Hydrophobic Surfaces. 2015. J Pharm Sci 104:593-601
Kapp, S. J., Larsson, I., van de Weert, Marco, Ćardenas, M. & Jørgensen, Lene, 2015, In: Journal of Pharmaceutical Sciences. 104, 10, p. 3587 1 p.Research output: Contribution to journal › Comment/debate › Research
- 2014
- Published
Design and processing of nanogels as delivery systems for peptides and proteins: Therapeutic Delivery
Arnfast, L., Madsen, C. G., Jørgensen, Lene & Baldursdottir, S., 1 Jun 2014, In: Therapeutic Delivery. 5, 6, p. 691-708 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elucidating the mechanisms of protein antigen adsorption to the CAF/NAF liposomal vaccine adjuvant systems: Effect of charge, fluidity and antigen-to-lipid ratio
Hamborg, M., Rose, F., Jørgensen, Lene, Bjorklund, K., Pedersen, H., Christensen, D. & Foged, Camilla, 25 Apr 2014, In: BBA General Subjects. 1838, 8, p. 2001-2010 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complex coacervates of hyaluronic acid and lysozyme: Effect on protein structure and physical stability
Water, J. J., Schack, M. M., Velazquez-Campoy, A., Maltesen, M. J., van de Weert, Marco & Jørgensen, Lene, 1 Jan 2014, In: European Journal of Pharmaceutics and Biopharmaceutics. 88, 2, p. 325-331 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Responsive gelation of hydrophobized linear polymer
Madsen, C. G., Toeth, J., Jørgensen, Lene, Hietala, S., Baldursdottir, S. G. & Hietala, S., 2014. 4 p.Research output: Contribution to conference › Paper › Research
- 2013
- Published
The physical stability of the recombinant tuberculosis fusion antigens h1 and h56
Hamborg, M., Kramer, R., Schanté, C. E., Agger, E. M., Christensen, D., Jørgensen, Lene, Foged, Camilla & Middaugh, C. R., Oct 2013, In: Journal of Pharmaceutical Sciences. 102, 10, p. 3567-78 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design and characterization of core-shell mPEG-PLGA composite microparticles for development of cell-scaffold constructs
Wen, Y., Gallego, M. R., Nielsen, L. F., Jørgensen, Lene, Møller, E. H. & Nielsen, Hanne Mørck, Sep 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 1, p. 87-98 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The challenges in and importance of analysing protein structure and physical stability in complex formulations
Jørgensen, Lene, Jensen, M. G., Roest, N., Pinholt, C. & van de Weert, Marco, 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 347-353 7 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Biologiske lægemidler - fra molekyle til medicin
Nielsen, Hanne Mørck, Foged, Camilla, Jørgensen, Lene & Frøkjær, Sven, 2013, In: Lægemiddelforskning. p. 12-14Research output: Contribution to journal › Journal article › Research
- Published
Effect of mixed solvents on polymer conformation –correlation between the Hildebrand/Hansen solubility parameters and the intrinsic viscosity of polymer solutions
Madsen, C. G., Skov, A., Jørgensen, Lene, Baldursdottir, S. G. & Medlicott, N., 2013, In: Nordic Rheology Society Annual Transactions. 21, p. 354-352Research output: Contribution to journal › Conference article › Research
- Published
Influence of acylation on the adsorption of GLP-2 to hydrophobic surfaces
Pinholt, C., Kapp, S. J., Bukrinsky, J. T., Hostrup, S., Frøkjær, Sven, Norde, W. & Jørgensen, Lene, 2013, In: International Journal of Pharmaceutics. 440, 1, p. 63-71 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein antigen adsorption to the DDA/TDB liposomal adjuvant: effect on protein structure, stability, and liposome physicochemical characteristics
Hamborg, M., Jørgensen, Lene, Bojsen, A. R., Christensen, D. & Foged, Camilla, 2013, In: Pharmaceutical Research. 30, 1, p. 140-55 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein nanopharmaceuticals - concepts and safety considerations
Møller, E. H., Jørgensen, Lene & Medlicott, N. J., 2013, Nanopharmaceutics: the potential application of nanomaterials. Liang, X-J. (ed.). Singapore: World Scientific, p. 49-Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Towards the understanding of complex fluids in pharmaceutical sciences
Pedersen, P. B., Pekka Pajander, J., Mullertz, Anette , Vilmann, Peter, Jørgensen, Lene & Baldursdottir, S. G., 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 393 401 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
pH dependent polymer surfactants for hindering BSA adsorption to oil-water interface
Colak, S., Guzman, P., Medlicott, N., Tehnu, H., Niskanen , J., Alhoranta, A., Jørgensen, Lene & Baldursdottir, S. G., 2013, In: Nordic Rheology Society Annual Transactions. 21, p. 329-334Research output: Contribution to journal › Conference article › Research
- 2012
- Published
Calcipotriol delivery into the skin with PEGylated liposomes
Knudsen, N. Ø., Rønholt, Stine, Salte, R. D., Jørgensen, Lene, Thormann, T., Basse, L. H., Hansen, J., Frøkjær, Sven & Foged, Camilla, 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 81, 3, p. 532-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of two methods detecting lysozyme adsorption to oil-water interface in the presence of surfactants
Baldursdottir, S. G. & Jørgensen, Lene, 2012. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Correlation between enzyme activity an stability of a protease, an alpha-amaylase and a lipase in a simplified liquid laundry detergent system, determined by differential scanning calorimetry
Lund, H., Kaasgaard, S. G., Skagerlind, P., Jørgensen, Lene, Jørgensen, C. I. & van de Weert, Marco, 2012, In: Journal of Surfactants and Detergents. 15, p. 9-21Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Delivery of dermatan sulfate from polyelectrolyte complex-containing alginate composite microspheres for tissue regeneration
Wen, Y., Grøndahl, L., Gallego, M. R., Jørgensen, Lene, Møller, E. H. & Nielsen, Hanne Mørck, 2012, In: Biomacromolecules. 13, p. 905-917Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design of cyclic RKKH peptide-conjugated PEG liposomes targeting the integrin a2ß1 receptor
Knudsen, N. Ø., Schiffelers, R. M., Jørgensen, Lene, Hansen, J., Frøkjær, Sven & Foged, Camilla, 2012, In: International Journal of Pharmaceutics. 428, 1-2, p. 171-177Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formation of dielectric layers and charge regulation in protein adsorption at biomimetic interfaces
Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, H., 2012, In: Langmuir. 28, 3, p. 1804-1815Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formulation technologies to overcome unfavorable properties of peptides and proteins for pulmonary delivery
Wan, F., Møller, E. H., Yang, Mingshi & Jørgensen, Lene, 2012, In: Drug Discovery Today: Technologies. 9, 2, p. e141-e146Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Infrared spectroscopy to characterize protein aggregates
van de Weert, Marco & Jørgensen, Lene, 2012, Analysis of aggregates and particles in protein pharmaceuticals. Mahler, H-C. & Jiskoot, W. (eds.). Hoboken: Wiley, p. 227-248Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Interaction of peptidomimetics with bilayer membranes: biophysical characterization and cellular uptake
Jing, X., Kasimova, M. R., Simonsen, A. H., Jørgensen, Lene, Malmsten, M., Franzyk, Henrik & Foged, Camilla, 2012, In: Langmuir. 28, 11, p. 5167-5175Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Membrane adsorption and binding, cellular uptake and cytotoxicity of cell-penetrating peptidomimetics with α-peptide/β-peptoid backbone: effects of hydrogen bonding and α-chirality in the β-peptoid residues
Jing, X., Yang, M., Kasimova, M. R., Malmsten, M., Franzyk, Henrik, Jørgensen, Lene, Foged, Camilla & Nielsen, Hanne Mørck, 2012, In: BBA General Subjects. 1818, 11, p. 2660-2668 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protease and amylase stability in the presence of chelators used in laundry detergent applications: correlation between chelator properties and enzyme stability in liquid detergents
Lund, H., Kaasgaard, S. G., Skagerlind, P., Jørgensen, Lene, Jørgensen, C. I. & van de Weert, Marco, 2012, In: Journal of Surfactants and Detergents. 15, 3, p. 265-276Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rheological Characterization of Lysozyme Adsorption to Oil-Water Interface Using Double Wall Ring Geometry
Baldursdottir, S. G. & Jørgensen, Lene, 2012.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- 2011
- Published
Protein adsorption at charged surfaces: the role of electrostatic interactions and interfacial charge regulation
Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, Henrik Elvang, 15 Mar 2011, In: Langmuir. 27, 6, p. 2634-2643 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of biodegradable nanocomposite scaffolds for autologous cell therapy
Wen, Y., Gallego, M. R., Nielsen, L. F., Jørgensen, Lene, Everland, H., Møller, E. H. & Nielsen, Hanne Mørck, 1 Jan 2011, In: European Cells and Materials. 21, SUPPL.1, 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adsorption of insulin with varying self-association profiles to a solid Teflon surface-Influence on protein structures, fibrillation tendency and thermal stability
Jørgensen, Lene, Bennedsen, P., Hoffmann, S. V., Pinholt, C., Krogh, R. L., Jensen, M. G., Hostrup, S. & Burkinksky, J. T., 2011, In: European Journal of Pharmaceutical Sciences. 42, 5, p. 509-516Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biodegradable nanocomposite microparticles as drug delivering injectable cell scaffolds
Wen, Y., Gallego, M. R., Nielsen, L. F., Jørgensen, Lene, Everland, H., Møller, E. H. & Nielsen, Hanne Mørck, 2011, In: Journal of Controlled Release. 156, 1, p. 11-20Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incorporation of a synthetic mycobacterial monomycoloyl glycerol analogue stabilizes dimethyldioctadecylammonium liposomes and potentiates their adjuvant effect in vivo
Nordly, P. J., Korsholm, K. S., Pedersen, E. A., Khilji, T. S., Franzyk, Henrik, Jørgensen, Lene, Nielsen, Hanne Mørck, Agger, E. M. & Foged, Camilla, 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 77, 1, p. 89-98Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of PEGylation with linear and branched PEG chains on the adsorption of glucagon to hydrophobic surfaces
Pinholt, C., Bukrinsky, J. T., Hostrup, S., Frøkjær, Sven, Norde, W. & Jørgensen, Lene, 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 77, 1, p. 139-147Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of acylation on the adsorption of insulin to hydrophobic surfaces
Pinholt, C., Hostrup, S., Bukrinsky, J. T., Frøkjær, Sven & Jørgensen, Lene, 2011, In: Pharmaceutical Research. 28, p. 1031-1040Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein adsorption at charged surfaces: The role of electrostatic interactions and interacial charge regulation
Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, H., 2011, In: Langmuir. 27, p. 2634-2643Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting of liposome-associated calcipotriol to the skin: effect of liposomal membrane fluidity and skin barrier integrity
Knudsen, N. Ø., Jørgensen, Lene, Hansen, J., Vermehren, C., Frøkjær, Sven & Foged, Camilla, 2011, In: International Journal of Pharmaceutics. 416, p. 478-485Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The importance of interfaces in protein drug delivery - why is protein adsorption of interest in pharmaceutical formulations ?
Pinholt, C., Hartvig, R. A., Medlicott, N. J. & Jørgensen, Lene, 2011, In: Expert Opinion on Drug Delivery. 8, 7, p. 949-964Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of size, structure and hydrophilicity of model surfactants on the adsorption of lysozyme to oil-water interface-Interacial shear measurements
Baldursdóttir, S. G. & Jørgensen, Lene, 2011, In: Colloids and Surfaces B: Biointerfaces. 87, p. 96-102Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
A synthetic mycobacterial monomycoloyl glycerol analogue stabilizes DDA liposomes
Nordly, P. J., Pedersen, E. A., Khiljii, T. S., Agger, E. M., Jørgensen, Lene, Nielsen, Hanne Mørck, Korsholm, K. S., Franzyk, Henrik & Foged, Camilla, 2010, In: CRS Newsletter. 27, 2, p. 12 14 p.Research output: Contribution to journal › Journal article › Research
- Published
Influence of glycosylation on the adsorption of Thermomyces lannuginosus lipase to hydrophobic and hydrophilic surfaces
Pinholt, C., Fanø, M., Wiberg, C., Hostrup, S., Bukrinsky, J. T., Frøkjær, Sven, Norde, W. & Jørgensen, Lene, 2010, In: European Journal of Pharmaceutical Sciences. 40, 4, p. 273-281Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interfacial complexes between a protein and lipophilic ions at an oil - water interface
Hartvig, R. A., Méndez, M. A., van de Weert, Marco, Jørgensen, Lene, Østergaard, Jesper, Girault, H. H. & Jensen, H., 2010, In: Analytical Chemistry. 82, 18, p. 7699-7705Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Issues in Development of Biodrug Delivery Systems
Jørgensen, Lene, Frøkjær, Sven & Nielsen, Hanne Mørck, 2010, Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development. Morishita, M. & Park, K. (eds.). 1 ed. Informa Healthcare, p. 13-25Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Issues in development of biodrug delivery systems
Jørgensen, Lene, Frøkjær, Sven & Nielsen, Hanne Mørck, 2010, Biodrug delivery systems: fundamentals, applications and clinical development. Morishita, M. & Park, K. (eds.). New York: Informa Healthcare, p. 13-25Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Multivariate analysis of protein physical stability
Guzman, P., Jørgensen, Lene, Strachan, C., Rades, T. & Medlicott, N., 2010.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Penetration of gel and liquid state liposomes into barrier-impaired skin
Knudsen, N. Ø., Frøkjær, Sven, Hansen, J., Jørgensen, Lene & Foged, Camilla, 2010, In: Journal of Pharmacy and Pharmacology. p. 793Research output: Contribution to journal › Conference article › Research › peer-review
- Published
Proteiner i lægemidler - de sætter sig alle de forkerte steder
Baldursdóttir, S. G., Nielsen, S. H., Fullerton, M. & Jørgensen, Lene, 2010, In: Lægemiddelforskning. 2010, p. 43-45Research output: Contribution to journal › Journal article › Research
- Published
Adsorption of proteins at the oil/water inerface - observation of protein adsorption by interfacial shear stress measurements
Baldursdóttir, S. G., Fullerton, M. S., Nielsen, S. H. & Jørgensen, Lene, 2010, In: Colloids and Surfaces B: Biointerfaces. 79, p. 41-46Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Challenges in Delivery of Biopharmaceuticals; the Need for Advanced Delivery Systems
Nielsen, Hanne Mørck & Jørgensen, Lene, 11 Dec 2009, Delivery Technologies for Biopharmaceuticals: Peptides, Proteins, Nucleic Acids and Vaccines. John Wiley & Sons, Ltd, p. 1-8 8 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Analysis of protein physical stability in lipid based delivery systems: the challenges of lipid drug delivery systems
Jørgensen, Lene, Martins, S. & van de Weert, Marco, 2009, In: Journal of Biomedical Nanotechnology. 5, 4, p. 401-408Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biotechnology-based pharmaceuticals
Jørgensen, Lene, Nielsen, Hanne Mørck & Frøkjær, Sven, 2009, Modern pharmaceutics: applications and advances. Florence, A. T. & Siepmann, J. (eds.). 5 ed. New York: Informa Healthcare, Vol. 2. p. 259-293 (Drugs and the Pharmaceutical Sciences, Vol. 188).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Delivery technologies for biopharmaceuticals: Peptides, proteins, nucleic acids and vaccines
Jørgensen, Lene & Nielsen, Hanne Mørck, 2009, Wiley. 413 p.Research output: Book/Report › Book › Research › peer-review
- Published
Determination of liposome-buffer distribution coefficients of charged drugs by capillary electrophoresis frontal analysis
Franzen, U., Jørgensen, Lene, Larsen, C. S., Heegaard, N. H. H. & Østergaard, Jesper, 2009, In: Electrophoresis. 30, 15, p. 2711-2719Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Infrared spectroscopy of protein pharmaceuticals
van de Weert, Marco & Jørgensen, Lene, 2009, Advances in Biomedical Spectroscopy: Biological and Biomedical Infrared Spectrocopy. Barth, A. & Haris, P. I. (eds.). Amsterdam: IOS Press, Vol. 2. p. 168-177Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- Published
Lipid based drug delivery systems for proteins: Physical stability of proteins at the oil-water interface
Jørgensen, Lene, 2009, VDM Verlag Dr. Müller Aktiengesellschaft & C o. KG.Research output: Book/Report › Book › Research › peer-review
- Published
Protein adsorption and displacement at lipid layers determined by total internal reflection fluorescence (TIRF)
Jørgensen, Lene, Krøyer Wood, G., Rosenkrands, I., Petersen, C. & Christensen, D., 2009, In: Journal of Liposome Research. 19, 2, p. 99-104Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recent trends in stabilising peptides and proteins in pharmaceutical formulation - considerations in the choice of excipients
Jørgensen, Lene, Hostrup, S., Møller, E. H. & Grohganz, Holger, 2009, In: Expert Opinion on Drug Delivery. 6, 11, p. 1219-1230Research output: Contribution to journal › Review › Research
- 2008
- Published
Alternative routes of administration for systemic delivery of protein pharmaceuticals
Møller, E. H. & Jørgensen, Lene, 2008, In: Drug Discovery Today: Technologies. 5, 2-3, p. 89-94Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Drug - liposome distribution phenomena studied by capillary electrophoresis-frontal analysis
Østergaard, Jesper, Jørgensen, Lene, Thomsen, A. E., Larsen, Susan Weng, Larsen, C. S. & Jensen, H., 2008, In: Electrophoresis. 29, 16, p. 3320 - 3324Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Karakterisering af lægemiddelstof-liposom-vekselvirkninger i et kapillar
Østergaard, Jesper, Franzen, U., Møller, E. H., Jørgensen, Lene, Larsen, C. S. & Jensen, H., 2008, In: Dansk Kemi. 89, 8, p. 27-29Research output: Contribution to journal › Journal article › Research
- Published
Metode til screening af modificerede proteinlægemidler under opbevaring
Petersen, C., Jørgensen, Lene, Hostrup, S., Bukrinsky, J. T. & Frøkjær, Sven, 2008, In: Lægemiddelforskning. p. 16-18Research output: Contribution to journal › Journal article › Communication
- Published
Studies on human insulin adsorption kinetics at an organic-aqueous interface determined using a label-free electroanalytical approach
Thomsen, A. E., Jensen, H., Jørgensen, Lene, van de Weert, Marco & Østergaard, Jesper, 2008, In: Colloids and Surfaces B: Biointerfaces. 63, 2, p. 243-248Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Liposomer i lægemiddelforskning
Franzen, U., Jørgensen, Lene, Larsen, C. S., Jensen, H. & Østergaard, Jesper, 2007, In: Lægemiddelforskning. p. 14-15Research output: Contribution to journal › Journal article › Communication
- Published
Probing insulin's secondary structure after entrapment into alginate/chitosan nanoparticles
Sarmento, B., Ferreira, D. C., Jørgensen, Lene & van de Weert, Marco, 2007, In: European Journal of Pharmaceutics and Biopharmaceutics. 65, 1, p. 10-17Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Kinetics of insulin adsorption at the oil-water interface and diffusion properties of adsorbed layers monitored using fluorescence correlation spectroscopy
Donsmark, J., Jørgensen, Lene, Mollmann, S., Frøkjær, Sven & Rischel, C., 1 Jan 2006, In: Pharmaceutical Research. 23, 1, p. 148-155 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interfacial adsorption of insulin - conformational changes and reversibility of adsorption
Mollmann, S. H., Jørgensen, Lene, Bukrinsky, J. T., Elofsson, U., Norde, W. & Frøkjær, Sven, 2006, In: European Journal of Pharmaceutical Sciences. 27, 2-3, p. 194-204Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinetics of insulin adsorption and gelation at the oil-water interface monitored using fluorescence correlation spectroscopy
Donsmark, J., Jørgensen, Lene, Mollmann, S. H., Frøkjær, Sven & Rischel, C., 2006, In: Pharmaceutical Research. 23, 1, p. 148-155Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Factors of importance for a successful delivery system for proteins
van de Weert, Marco, Jørgensen, Lene, Horn Moeller, E. & Frøkjær, Sven, Nov 2005, In: Expert Opinion on Drug Delivery. 2, 6, p. 1029-37 9 p.Research output: Contribution to journal › Review › Research › peer-review
- 2004
- Published
Probing structural changes of proteins incorporated into water-in-oil emulsions
Jørgensen, Lene, van de Weert, Marco, Vermehren, C., Bjerregaard, S. & Frøkjær, Sven, Jul 2004, In: Journal of Pharmaceutical Sciences. 93, 7, p. 1847-59 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro release of insulin aspart incorporated into water-in-oil emulsions
Jørgensen, Lene, Vermehren, Charlotte, Bjerregaard, S. & Frøkjær, Sven, 2004, In: Journal of Drug Delivery Science and Technology. 14, 6, p. 455-459Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Micropipette manipulation a technique to evaluate the stability of water-in-oil emulsions containing proteins
Jørgensen, Lene, Kim, D. H., Vermehren, Charlotte, Bjerregaard, S. & Frøkjær, Sven, 2004, In: Journal of Pharmaceutical Sciences. 93, 12, p. 2994-3003Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
Secondary structure alteration in insulin and growth hormone water-in-oil emulsions
Jørgensen, Lene, Vermehren, Charlotte, Bjerregaard, S. & Frøkjær, Sven, 2003, In: Internation Journal of Pharmaceutics. 254, 1, p. 7-10Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1299770
Most downloads
-
1796
downloads
Proteiner i lægemidler - de sætter sig alle de forkerte steder
Research output: Contribution to journal › Journal article › Research
Published -
157
downloads
Fluorophore labeling of a cell-penetrating peptide significantly alters the mode and degree of biomembrane interaction
Research output: Contribution to journal › Journal article › Research › peer-review
Published