Kaare Villum Grunddal

Kaare Villum Grunddal

Assistant Professor


  1. 2022
  2. Published

    Actions of glucagon-like peptide-1 receptor ligands in the gut

    Holst, Jens Juul, Andersen, Daniel Bjørklund & Grunddal, Kaare Villum, 2022, In: British Journal of Pharmacology. 179, 4, p. 727-742

    Research output: Contribution to journalReviewResearchpeer-review

  3. Published

    Expression Profile of the GLP-1 Receptor in the Gastrointestinal Tract and Pancreas in Adult Female Mice

    Grunddal, Kaare Villum, Jensen, E. P., Ørskov, Cathrine, Andersen, Daniel Bjørklund, Windeløv, Johanne Agerlin, Poulsen, Steen Seier, Rosenkilde, M. M., Knudsen, L. B., Pyke, C. & Holst, Jens Juul, 2022, In: Endocrinology. 163, 1

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Opposing roles of the entero-pancreatic hormone urocortin-3 in glucose metabolism in rats

    Grunddal, Kaare Villum, Trammell, Sam, Bæch-Laursen, C., Andersen, Daniel Bjørklund, Xu, S. F. S., Andersen, H., Gillum, M. P., Ghiasi, S. M., Novak, Ivana, Tyrberg, B., Li, C., Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul & Kuhre, Rune Ehrenreich, 2022, In: Diabetologia. 65, p. 1018–1031

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2021
  6. Published

    Adhesion receptor ADGRG2/GPR64 is in the GI-tract selectively expressed in mature intestinal tuft cells

    Grunddal, Kaare Villum, Tonack, S., Egerod, Kristoffer Lihme, Thompson, J. J., Petersen, N., Engelstoft, M. S., Vagne, C., Keinse, C., Gradwohl, G., Offermanns, S. & Schwartz, Thue W., 2021, In: Molecular Metabolism. 51, 17 p., 101231.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Decreased number of colonic tuft cells in quiescent ulcerative colitis patients

    Kjærgaard, S., Jensen, Thorbjørn Søren Rønn, Feddersen, U. R., Bindslev, Niels, Grunddal, Kaare Villum, Poulsen, Steen Seier, Rasmussen, Hanne Borger, Budtz-Joergensen, Esben & Berner-Hansen, M., 2021, In: European journal of gastroenterology & hepatology. 33, 6, p. 817-824 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Development of a bispecific immune engager using a recombinant malaria protein

    Nordmaj, Mie Anemone, Roberts, M. E., Sachse, E. S., Dagil, Robert, Andersen, Anne Poder, Skeltved, Nanna, Grunddal, Kaare Villum, Erdogan, Sayit Mahmut, Choudhary, Swati, Gustavsson, Tobias, Ørum-madsen, M. S., Moskalev, I., Tian, W., Yang, Zhang, Clausen, Thomas Mandel, Theander, Thor Grundtvig, Daugaard, M., Nielsen, Morten Agertoug & Salanti, Ali, 2021, In: Cell Death & Disease. 12, 4, 11 p., 353.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Using a Reporter Mouse to Map Known and Novel Sites of GLP-1 Receptor Expression in Peripheral Tissues of Male Mice

    Andersen, Daniel Bjørklund, Grunddal, Kaare Villum, Pedersen, Jens, Kuhre, Rune Ehrenreich, Lund, M. L., Holst, Jens Juul & Ørskov, Cathrine, 2021, In: Endocrinology. 162, 3, bqaa246.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2020
  11. Published

    Next Generation Diabetes Scientists Shape Global Research Culture: A reflective proposal from postdoctoral researchers in diabetes research

    Gonzalez-Franquesa, A., Carrasquilla Lopez, G. D., Mamidi, A., Ghiasi, S. M., Juel, H. B., Falk, S., Isidor, M. S., Gillberg, L. M. E., Huang, L. O., Quist, J. S., Knudsen, J. R., Quaranta, R., Tozzi, M., Mikkelsen, R. B., Dall, M., Drag, M. H., Small, L. B., Altıntaş, A., Osborne, B., Modvig, I. M. & 11 others, Husted, Anna Sofie, Brown, E. L., Bak, Emilie Glad, Bastos Peluso, A. A., Finger, Fabian Michael, Grunddal, Kaare Villum, Rupar, K., Henningsen, J. B., Pedersen, M. H., Plucinska, Kaja & Attendees of the Danish Diabetes Academy Winter School 2019, A. O. T. D. D. A. W. S. 2., 2020, In: Acta Physiologica. 229, 2, 5 p., e13455.

    Research output: Contribution to journalComment/debateResearch

  12. Published

    Secretin release after Roux-en-Y gastric bypass reveals a population of glucose-sensitive S cells in distal small intestine

    Modvig, Ida Marie, Andersen, Daniel Bjørklund, Grunddal, Kaare Villum, Kuhre, Rune Ehrenreich, Martinussen, C., Christiansen, Charlotte Bayer, Ørskov, Cathrine, Larraufie, P., Kay, R. G., Reimann, F., Gribble, F. M., Hartmann, Bolette, Bojsen-Moller, K. N., Madsbad, Sten, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2020, In: International Journal of Obesity. 44, 9, p. 1859-1871

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2019
  14. Published

    Long-Acting Neurotensin Synergizes With Liraglutide to Reverse Obesity Through a Melanocortin-Dependent Pathway

    Ratner, C., He, Z., Grunddal, Kaare Villum, Skov, Louise Julie, Hartmann, Bolette, Zhang, F., Feuchtinger, A., Bjerregaard, Anette, Christoffersen, Christina, Tschöp, M. H., Finan, B., DiMarchi, R. D., Leinninger, G. M., Williams, K. W., Clemmensen, Christoffer & Holst, Birgitte, 2019, In: Diabetes. 68, 6, p. 1329-1340

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Paracrine Crosstalk between Intestinal L- and D-cells Controls Secretion of Glucagon-Like Peptide-1 in mice

    Jepsen, Sara Lind, Grunddal, Kaare Villum, Albrechtsen, Nicolai Jacob Wewer, Engelstoft, M. S., Gabe, M. B. N., Jensen, E. P., Ørskov, Cathrine, Poulsen, Steen Seier, Rosenkilde, M. M., Pedersen, J., Gribble, F. M., Reimann, F., Deacon, Carolyn F., Schwartz, Thue W., Christ, A. D., Martin, R. E. & Holst, Jens Juul, 2019, In: American Journal of Physiology: Endocrinology and Metabolism. 317, 6, p. E1081-E1093

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2016
  17. Published

    Neurotensin Is Co-Expressed, Co-Released And Acts Together With Glp-1 And Pyy In Enteroendocrine Control Of Metabolism

    Grunddal, Kaare Villum, Ratner, C. F., Svendsen, B., Sommer, F., Engelstoft, M. S., Madsen, A. N., Pedersen, Jens, Nøhr, M. K., Egerod, Kristoffer Lihme, Nawrocki, A. R., Kowalski, T., Howard, A. D., Poulsen, Steen Seier, Offermanns, S., Bäckhed, G. F., Holst, Jens Juul, Holst, Birgitte & Schwartz, Thue W., Jan 2016, In: Endocrinology. 157, 1, p. 176-94 19 p., en20151600.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2015
  19. Published

    Research Resource: A Chromogranin A Reporter for Serotonin and Histamine Secreting Enteroendocrine Cells

    Engelstoft, M. S., Lund, M. L., Grunddal, Kaare Villum, Egerod, Kristoffer Lihme, Osborne-Lawrence, S., Poulsen, Steen Seier, Zigman, J. M. & Schwartz, Thue W., Nov 2015, In: Molecular endocrinology (Baltimore, Md.). 29, 11, p. 1658-71 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Transcriptional and Functional Characterization of the G Protein-Coupled Receptor Repertoire of Gastric Somatostatin Cells

    Egerod, Kristoffer Lihme, Engelstoft, M. S., Lund, M. L., Grunddal, Kaare Villum, Zhao, M., Barir-Jensen, D., Nygaard, E. B., Petersen, N., Holst, Jens Juul & Schwartz, Thue W., Nov 2015, In: Endocrinology. 156, 11, p. 3909-23 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The glucagon-like peptide 2 receptor is expressed in enteric neurons and not in the epithelium of the intestine

    Pedersen, Jens, B. Pedersen, N., Brix, S. W., Grunddal, Kaare Villum, Rosenkilde, Mette, Hartmann, Bolette, Ørskov, Cathrine, Poulsen, Steen Seier & Holst, Jens Juul, May 2015, In: Peptides. 67, p. 20-28 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2013
  23. Published

    GPR41/FFAR3 and GPR43/FFAR2 as Cosensors for Short-Chain Fatty Acids in Enteroendocrine Cells vs FFAR3 in Enteric Neurons and FFAR2 in Enteric Leukocytes

    Nøhr, M. K., Pedersen, M. H., Gille, A., Egerod, Kristoffer Lihme, Engelstoft, M. S., Husted, Anna Sofie, Sichlau, R. M., Grunddal, Kaare Villum, Poulsen, Steen Seier, Han, S., Jones, R. M., Offermanns, S. & Schwartz, Thue W., 24 Jul 2013, In: Endocrinology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Glucose metabolism is altered after loss of L cells and α-cells but not influenced by loss of K cells

    Pedersen, J., Ugleholdt, Randi Kjærsgaard, Jørgensen, S. M., Windeløv, Johanne Agerlin, Grunddal, Kaare Villum, Schwartz, Thue W., Füchtbauer, E., Poulsen, Steen Seier, Holst, Peter Johannes & Holst, Jens Juul, 1 Jan 2013, In: American Journal of Physiology: Endocrinology and Metabolism. 304, 1, p. E60-73 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2012
  26. Published

    A Major Lineage of Enteroendocrine Cells Coexpress CCK, Secretin, GIP, GLP-1, PYY, and Neurotensin but Not Somatostatin

    Egerod, Kristoffer Lihme, Engelstoft, M. S., Grunddal, Kaare Villum, Nøhr, M. K., Secher, A., Sakata, I., Pedersen, Jens, Windeløv, Johanne Agerlin, Füchtbauer, E., Olsen, Jørgen, Sundler, F., Christensen, Jan Pravsgaard, Wierup, N., Olsen, Jesper Velgaard, Holst, Jens Juul, Zigman, J. M., Poulsen, Steen Seier & Schwartz, Thue W., 1 Dec 2012, In: Endocrinology. 153, 12, p. 5782-95 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 37722619