Birthe Brandt Kragelund

Birthe Brandt Kragelund

Professor


  1. 2024
  2. Published

    Checkpoint activation by Spd1: a competition-based system relying on tandem disordered PCNA binding motifs

    Olsen, Johan Gotthardt, Prestel, Andreas, Kassem, N., Broendum, S. S., Hossain, Mohammad Shamim, Simonsen, Signe, Grysbæk, M., Mortensen, J., Rytkjær, L. L., Haxholm, G. W., Marabini, R., Holmberg, Christian, Carr, A. M., Crehuet, R., Nielsen, Olaf & Kragelund, Birthe Brandt, 2024, In: Nucleic acids symposium series. 52, 4, p. 2030–2044 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    DNA binding redistributes activation domain ensemble and accessibility in pioneer factor Sox2

    Bjarnason, S., McIvor, J. A. P., Prestel, Andreas, Demény, K. S., Bullerjahn, J. T., Kragelund, Birthe Brandt, Mercadante, D. & Heidarsson, P. O., 2024, In: Nature Communications. 15, 1, 16 p., 1445.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Effects of ethanol or ethylene glycol exposure on PPARγ and aromatase expression in adipose tissue

    Ardenkjær-Skinnerup, J., Saar, Daniel, Christiansen, S., Svingen, T., Hadrup, N., Brown, K. A., Emanuelli, Brice, Kragelund, Birthe Brandt, Ravn-Haren, G. & Vogel, U., 2024, In: Biochemistry and Biophysics Reports. 38, 9 p., 101742.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Molecular switching in transcription through splicing and proline-isomerization regulates stress responses in plants

    Theisen, Frederik Friis, Prestel, Andreas, Elkjær, Steffie Martina H, Leurs, Y. H. A., Morffy, N., Strader, L. C., O'Shea, Charlotte, Teilum, Kaare, Kragelund, Birthe Brandt & Skriver, Karen, 2024, In: Nature Communications. 15, 1, 13 p., 592.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Myotubularin-related-protein-7 inhibits mutant (G12V) K-RAS by direct interaction

    Weidner, P., Saar, D., Söhn, M., Schroeder, T., Yu, Y., Zöllner, F. G., Ponelies, N., Zhou, X., Zwicky, A., Rohrbacher, F. N., Pattabiraman, V. R., Tanriver, M., Bauer, A., Ahmed, H., Ametamey, S. M., Riffel, P., Seger, R., Bode, J. W., Wade, R. C., Ebert, M. P. A. & 2 others, Kragelund, Birthe Brandt & Burgermeister, E., 2024, In: Cancer Letters. 588, 19 p., 216783.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    PPARγ antagonists induce aromatase transcription in adipose tissue cultures

    Ardenkjær-Skinnerup, J., Saar, Daniel, Petersen, Patricia Stephanie S, Pedersen, M., Svingen, T., Kragelund, Birthe Brandt, Hadrup, N., Ravn-Haren, G., Emanuelli, Brice, Brown, K. A. & Vogel, U., 2024, In: Biochemical Pharmacology. 222, 13 p., 116095.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The bacterial DNA sliding clamp, β-clamp: structure, interactions, dynamics and drug discovery

    Simonsen, Signe, Søgaard, C. K., Olsen, Johan Gotthardt, Otterlei, M. & Kragelund, Birthe Brandt, 2024, In: Cellular and Molecular Life Sciences. 81, 1, 25 p., 245.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The molecular basis for cellular function of intrinsically disordered protein regions

    Holehouse, A. S. & Kragelund, Birthe Brandt, 2024, In: Nature Reviews Molecular Cell Biology. 25, p. 187–211 25 p.

    Research output: Contribution to journalReviewResearchpeer-review

  10. 2023
  11. Published

    Modeling of flexible membrane-bound biomolecular complexes for solution small-angle scattering

    Barclay, A., Kragelund, Birthe Brandt, Arleth, Lise & Pedersen, Martin Cramer, Apr 2023, In: Journal of Colloid and Interface Science. 635, p. 611-621 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Assessment of models for calculating the hydrodynamic radius of intrinsically disordered proteins

    Pesce, Francesco, Newcombe, Estella Anne, Seiffert, P., Tranchant, E. E., Olsen, Johan Gotthardt, Grace, C. R., Kragelund, Birthe Brandt & Lindorff-Larsen, Kresten, 2023, In: Biophysical Journal. 122, 2, p. 310-321 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Comment on “Intrinsic protein disorder uncouples affinity from binding specificity

    Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2023, In: Protein Science. 32, 4, 2 p., e4602.

    Research output: Contribution to journalComment/debateResearchpeer-review

  14. Published

    Conformational entropy in molecular recognition of intrinsically disordered proteins

    Skriver, Karen, Theisen, Frederik Friis & Kragelund, Birthe Brandt, 2023, In: Current Opinion in Structural Biology. 83, 8 p., 102697.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    Evolutionary fine-tuning of residual helix structure in disordered proteins manifests in complex structure and lifetime

    Elkjær, Steffie Martina H, Due, Amanda Duncan, Christensen, L. F., Theisen, Frederik Friis, Staby, L., Kragelund, Birthe Brandt & Skriver, Karen, 2023, In: Communications Biology . 6, 11 p., 63.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Intrinsically Disordered Proteins as an Instrument for Research-Integrating Teaching

    Skriver, K., Sjørup, S. A., Langkilde, A. E., Balouka, E., Christensen, C. S., Carbel, K., Decker, J. N. V., Essenbæk, D. N., Gräf, J. F., Jessen, C. H., Kristensen, P., Merrild, C., Mortensen, T. S., Nalepa, I. F., Nordsteen, B. W., Svoren, S. K., van Hall, M., Weicher, J., Wind, M. L., Zhang, D. & 8 others, Saar, Daniel, Blæsild, H., Stahlhut, M., Andersen, K. V., Dagil, Robert, Vestergaard, Bente, Ryberg, Marie L. & Kragelund, Birthe Brandt, 2023, In: The Biophysicist. 4 , 2, p. 1-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Molecular insights into alginate beta-lactoglobulin A multivalencies: The foundation for their amorphous aggregates and coacervation

    Madsen, M., Prestel, Andreas, Madland, E., Westh, P., Tondervik, A., Sletta, H., Peters, G. H. J., Aachmann, F. L. L., Kragelund, Birthe Brandt & Svensson, B., 2023, In: Protein Science. 32, 2, 15 p., 4556.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Monomeric α-synuclein activates the plasma membrane calcium pump

    Kowalski, A., Betzer, C., Larsen, S. T., Gregersen, E., Newcombe, Estella Anne, Bermejo, M. C., Bendtsen, V. W., Diemer, J., Ernstsen, C. V., Jain, S., Bou, A. E., Langkilde, Annette Eva, Nejsum, L. N., Klipp, E., Edwards, R., Kragelund, Birthe Brandt, Jensen, P. H. & Nissen, Poul, 2023, In: EMBO Journal. 42, 23, 21 p., e111122.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Phosphorylation of Schizosaccharomyces pombe Dss1 mediates direct binding to the ubiquitin-ligase Dma1 in vitro

    Jacobsen, Nina Louise, Bloch, Magnus Borup, Millard, P. S., Ruidiaz, Sarah Frederiksen, Elsborg, Jonas Damgaard, Boomsma, Wouter, Hendus-Altenburger, R., Hartmann-Petersen, Rasmus & Kragelund, Birthe Brandt, 2023, In: Protein Science. 32, 9, 16 p., e4733.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published
  21. Published

    Structural characterization of human tryptophan hydroxylase 2 reveals that L-Phe is superior to L-Trp as the regulatory domain ligand

    Vedel, I. M., Prestel, Andreas, Zhang, Z., Skawinska, N. T., Stark, H., Harris, Pernille, Kragelund, Birthe Brandt & Peters, G. H. J., 2023, In: Structure (London, England : 1993). 31, 6, p. 689-699e6 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Targeted imaging of uPAR expression in vivo with cyclic AE105 variants

    Leth, Julie Maja, Newcombe, Estella Anne, Grønnemose, A. L., Jørgensen, Jesper Tranekjær, Qvist, K., Clausen, Anne Skovsbo, Knudsen, Line Bruhn Schneider, Kjær, Andreas, Kragelund, Birthe Brandt, Jørgensen, Thomas Jørgen Dyreborg & Ploug, Michael, 2023, In: Scientific Reports. 13, 17 p., 17248.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The prolactin receptor scaffolds Janus kinase 2 via co-structure formation with phosphoinositide-4,5-bisphosphate

    Araya-Secchi, R., Bugge, K., Seiffert, P., Petry, A., Haxholm, G. W., Lindorff-Larsen, Kresten, Pedersen, Stine Helene Falsig, Arleth, Lise & Kragelund, Birthe Brandt, 2023, In: eLife. 12, 27 p., e84645.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Tyrosine kinases compete for growth hormone receptor binding and regulate receptor mobility and degradation

    Chhabra, Y., Seiffert, P., Gormal, R. S., Vullings, M., Lee, C. M. M., Wallis, T. P., Dehkhoda, F., Indrakumar, S., Jacobsen, Nina Louise, Lindorff-Larsen, Kresten, Durisic, N., Waters, M. J., Meunier, F. A., Kragelund, Birthe Brandt & Brooks, A. J., 2023, In: Cell Reports. 42, 5, 26 p., 112490.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2022
  26. Published

    A context-dependent and disordered ubiquitin-binding motif

    Dreier, Jesper Elmsted, Prestel, Andreas, Martins, J. M., Brøndum, S. S., Nielsen, Olaf, Garbers, Anna Engstrøm, Suga, H., Boomsma, Wouter, Rogers, Joseph Matthew, Hartmann-Petersen, Rasmus & Kragelund, Birthe Brandt, 2022, In: Cellular and molecular life sciences : CMLS. 79, 9, 21 p., 484.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    A glutamine-based single α-helix scaffold to target globular proteins

    Escobedo, A., Piccirillo, J., Aranda, J., Diercks, T., Mateos, B., Garcia-Cabau, C., Sanchez-Navarro, M., Topal, B., Biesaga, M., Staby, L., Kragelund, Birthe Brandt, Garcia, J., Millet, O., Orozco, M., Coles, M., Crehuet, R. & Salvatella, X., 2022, In: Nature Communications. 13, 18 p., 7073.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Deciphering the Alphabet of Disorder-Glu and Asp Act Differently on Local but Not Global Properties

    Roesgaard, M. A., Lundsgaard, J. E., Newcombe, Estella Anne, Jacobsen, Nina Louise, Pesce, Francesco, Tranchant, E. E., Lindemose, Søren, Prestel, Andreas, Hartmann-Petersen, Rasmus, Lindorff-Larsen, Kresten & Kragelund, Birthe Brandt, 2022, In: Biomolecules. 12, 10, 19 p., 1426.

    Research output: Contribution to journalJournal articleResearchpeer-review

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