Hans Bräuner

Hans Bräuner

Prodekan for forskning


  1. Accepted/In press

    Differential G protein activation by the long and short isoforms of the dopamine D2 receptor

    Reiner-Link, David, Madsen, Jakob Sture, Gloriam, David E., Bräuner, Hans & Hauser, Alexander Sebastian, 2024, (Accepted/In press) In: British Journal of Pharmacology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Somatostatin venom analogs evolved by fish-hunting cone snails: From prey capture behavior to identifying drug leads

    Ramiro, Iris Bea L. , Bjørn-Yoshimoto, Walden, Imperial, J. S., Gajewiak, J., Salcedo, P. F., Watkins, M., Taylor, D., Resager, W., Ueberheide, B., Bräuner, Hans, Whitby, F. G., Hill, C. P., Martin, L. F., Patwardhan, A., Concepcion, G. P., Olivera, B. M. & Safavi-Hemami, H., 2022, In: Science Advances. 8, 12, 16 p., eabk1410.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Interactions between calcium and phosphorus in the regulation of the production of fibroblast growth factor 23 in vivo

    Quinn, S. J., Thomsen, A. R. B., Pang, J. L., Kantham, L., Brown, E. M., Bräuner, Hans, Pollak, M. & Goltzman, D., 1 Feb 2013, In: American Journal of Physiology: Endocrinology and Metabolism. 304, 3, p. E310-320

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Synthesis and pharmacological characterization at glutamate receptors of the four enantiopure isomers of tricholomic acid

    Pinto, A., Conti, P., De Amici, M., Tamborini, L., Madsen, Ulf, Nielsen, Birgitte, Christesen, T., Bräuner, Hans & De Micheli, C., 2008, In: Journal of Medicinal Chemistry. 51, 7, p. 2311-2315

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Biased agonism of clinically approved μ-opioid receptor agonists and TRV130 is not controlled by binding and signaling kinetics

    Pedersen, M. F., Wrobel, T. M., Marcher, Emil, Pedersen, D. S., Møller, T. C., Gabriele, F., Pedersen, H., Matosiuk, D., Foster, S. R., Bouvier, M. & Bräuner, Hans, 2020, In: Neuropharmacology. 166, 13 p., 107718.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Synthesis and muscarinic receptor pharmacology of a series of 4,5,6,7-tetrahydroisothiazolo[4,5-c]pyridine bioisosteres of arecoline

    Pedersen, H., Bräuner, Hans, Ball, R. G., Frydenvang, Karla Andrea, Meier, E., Bøgesø, K. P. & Krogsgaard-Larsen, Povl, 1999, In: Bioorganic & Medicinal Chemistry. 7, 5, p. 795-809 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    (1S, 3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a potent gamma-aminobutyric acid aminotransferase inactivator for the treatment of cocaine addiction

    Pan, Y., Gerasimov, M. R., Kvist, T., Wellendorph, Petrine, Madsen, K. K., Pera, E., Lee, H., Schousboe, Arne, Chebib, M., Bräuner, Hans, Craft, C. M., Brodie, J. D., Schiffer, W. K., Dewey, S. L., Miller, S. R. & Silverman, R. B., 1 Jan 2012, In: Journal of Medicinal Chemistry. 55, 1, p. 357-366

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Development of a medium throughput whole-cell microtiter plate Thr286 autophosphorylation assay for CaMKIIα using ELISA

    Palmelund, L. B., van Woerden, G. M., Bräuner, Hans & Wellendorph, Petrine, 2022, In: Journal of Pharmacological and Toxicological Methods. 118, 8 p., 107226.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Pharmacological characterization of novel small molecule agonists and antagonists for the orphan receptor GPR139

    Pallareti, L., Rath, T. F., Trapkov, Boris, Tsonkov, T., Nielsen, A. T., Harpsøe, Kasper, Gentry, P. R., Bräuner, Hans, Gloriam, David E. & Foster, S. R., 2023, In: European Journal of Pharmacology. 943, 175553.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    G protein-coupled receptor signaling analysis using homogenous time-resolved Förster resonance energy transfer (HTRF®) technology.

    Nørskov-Lauritsen, L., Thomsen, A. R. B. & Bräuner, Hans, 2014, In: International Journal of Molecular Sciences (Online). 15, 2, p. 2554-2572

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Role of post-translational modifications on structure, function and pharmacology of class C G protein-coupled receptors

    Nørskov-Lauritsen, L. & Bräuner, Hans, 2015, In: European Journal of Pharmacology. 763, p. 233-240 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    N-glycosylation and disulfide bonding affects GPRC6A receptor expression, function, and dimerization

    Nørskov-Lauritsen, L., Jørgensen, S. & Bräuner, Hans, 21 Jan 2015, In: FEBS Letters. 589, p. 588–597 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Identification of a novel scaffold for a small molecule GPR139 receptor agonist

    Nøhr, A. C., Shehata, M. A., Palmer, D., Pokhrel, R., Vallianou, M., Foster, S. R., Gentry, P. R., Gloriam, David E. & Bräuner, Hans, 7 Mar 2019, In: Scientific Reports. 9, 1, 10 p., 3802.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    A highly selective agonist for the metabotropic glutamate receptor mGluR2

    Nielsen, S. D., Fulco, M., Serpi, M., Nielsen, Birgitte, Hansen, M. B., Hansen, K. L., Thomsen, C., Brodbeck, R., Bräuner, Hans, Pellicciari, R., Norrby, P., Greenwood, J. R. & Clausen, Rasmus Prætorius, 23 Sep 2011, In: MedChemComm. 2, 11, p. 1120-1124

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Characterization of the real-time internalization of nine GPCRs reveals distinct dependence on arrestins and G proteins

    Møller, T. C., Moo, Ee Von, Inoue, A., Pedersen, M. F. & Bräuner, Hans, 2024, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1871, 1, 12 p., 119584.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells

    Møller, T. C., Pedersen, M. F., van Senten, Jeffrey Roy, Seiersen, S. D., Mathiesen, Jesper M., Bouvier, M. & Bräuner, Hans, 2020, In: Scientific Reports. 10, 1, 13 p., 17395.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Pharmacological characterization and modeling of the binding sites of novel 1,3-bis(pyridinylethynyl)benzenes as metabotropic glutamate receptor 5-selective negative allosteric modulators

    Mølck, C., Harpsøe, Kasper, Gloriam, David E., Clausen, Rasmus Prætorius, Madsen, Ulf, Pedersen, L., Jimenez, H. N., Nielsen, S. M., Mathiesen, Jesper M. & Bräuner, Hans, 2012, In: Molecular Pharmacology. 82, 5, p. 929-37 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    mGluR5: Exploration of Orthosteric and Allosteric Ligand Binding Pockets and Their Applications to Drug Discovery

    Mølck, C., Harpsøe, Kasper, Gloriam, David E., Mathiesen, Jesper M., Nielsen, S. M. & Bräuner, Hans, Oct 2014, In: Neurochemical Research. 39, 10, p. 1862-1875 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Quinazolin-4-one derivatives: A novel class of noncompetitive NR2C/D subunit-selective N-methyl-D-aspartate receptor antagonists

    Mosley, C. A., Acker, T. M., Hansen, K. B., Mullasseril, P., Andersen, K. T., Le, P., Vellano, K. M., Bräuner, Hans, Liotta, D. C. & Traynelis, S. F., 2010, In: Journal of Medicinal Chemistry. 53, 15, p. 5476-5490

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Calcium-Sensing Receptor Internalization Is β-Arrestin-Dependent and Modulated by Allosteric Ligands

    Mos, I., Jacobsen, S. E., Foster, S. R. & Bräuner, Hans, Oct 2019, In: Molecular Pharmacology. 96, 4, p. 463-474 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Arrestin-Dependent and -Independent Internalization of G Protein–Coupled Receptors: Methods, Mechanisms, and Implications on Cell Signaling

    Moo, Ee Von, van Senten, Jeffrey Roy, Bräuner, Hans & Møller, T. C., 2021, In: Molecular Pharmacology. 99, 4, p. 242-255

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Binding Mode of a Novel MPEP-Derived Metabotropic Glutamate Receptor Subtype 5 (mGluR5) NAM, 1,3-Bis(pyridin-2-ylethynyl)Benzene

    Molck, C., Harpsøe, Kasper, Gloriam, David E., Kaae, B. H., Jimenez, H. N., Uberti, M. A., Topiol, S., Clausen, Rasmus Prætorius, Madsen, Ulf, Nielsen, S. M., Mathiesen, Jesper M. & Bräuner, Hans, Sep 2011, In: Current Neuropharmacology. 9, p. 43-43

    Research output: Contribution to journalConference abstract in journalResearch

  23. Published

    Rigid nonproteinogenic cyclic amino acids as ligands for glutamate receptors: trans-tris(homoglutamic) acids

    Meyer, U., Bisel, P., Bräuner, Hans, Madsen, Ulf, Höfner, G., Wanner, K. T. & Frahm, A. W., Feb 2005, In: Chirality. 17, 2, p. 99-107

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. High throughput assays of cloned adrenergic, muscarinic, neurokinin, and neurotrophin receptors in living mammalian cells

    Messier, T. L., Dorman, C. M., Bräuner, Hans, Eubanks, D. & Brann, M. R., May 1995, In: Basic & Clinical Pharmacology & Toxicology. 76, 5, p. 308-11

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    cAMP biosensors applied in molecular pharmacological studies of G protein-coupled receptors

    Mathiesen, Jesper M., Vedel, L. & Bräuner, Hans, 2013, In: Methods in Enzymology. 522, p. 191-207 17 p.

    Research output: Contribution to journalJournal articleResearch

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