Jørn Bolstad Christensen

Jørn Bolstad Christensen

Associate Professor

Member of:


    1. 2024
    2. Published

      Macromolecular Pairing On Nanoparticle Surface Modulates Immune Response

      Haroon, H. B., Moghimi, S. M., Maghalaes, P. V., Papini, E., Christensen, Jørn Bolstad, Simberg, D. & Trohopoulos, P. N., 2024. 1 p.

      Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

    3. Accepted/In press

      A Systematic Study on the Physicochemical Interactions Between Polymeric Micelles and Mucin: Toward the Development of Optimal Drug Delivery Nanocarriers

      Tollemeto, M., Badillo-Ramírez, I., Thamdrup, L. H. E., Li, Y., Ghavami, M., Padial, T. P., Christensen, Jørn Bolstad, van Hest, J. & Boisen, A., 2024, (Accepted/In press) In: Advanced Materials Interfaces.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. 2023
    5. Published

      Bio-Oriented Synthesis and Molecular Docking Studies of 1,2,4-Triazole Based Derivatives as Potential Anti-Cancer Agents against HepG2 Cell Line

      Akhter, N., Batool, S., Khan, S. G., Rasool, N., Anjum, F., Rasul, A., Adem, S., Mahmood, S., Rehman, A. U., Nisa, M. U., Razzaq, Z., Christensen, Jørn Bolstad, Abourehab, M. A. S., Shah, S. A. A. & Imran, S., 2023, In: Pharmaceuticals. 16, 2, 18 p., 211.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      A Combined Experimental and Theoretical Study of ESR Hyperfine Coupling Constants for N,N,N’,N’-Tetrasubstituted p-Phenylenediamine Radical Cations

      Gleeson, R., Andersen, C. L., Rapta, P., Machata, P., Christensen, Jørn Bolstad, Hammerich, Ole & Sauer, Stephan P. A., 8 Feb 2023, In: International Journal of Molecular Sciences (Online). 24, 4, 17 p., 3447.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Dendrimers for theranostic applications

      Mejlsøe, S. L. & Christensen, Jørn Bolstad, 1 Jan 2023, Advanced Nanoformulations: Theranostic Nanosystems: Volume 3. Elsevier, p. 151-171 21 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    8. Published

      Dendrimers in drug delivery

      Mejlsøe, S. L. & Christensen, Jørn Bolstad, 2023, Advanced and Modern approaches for Drug Delivery. Elsevier, p. 357-387 31 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    9. Published

      A facile synthesis of 1,3,4-oxadiazole-based carbamothioate molecules: Antiseizure potential, EEG evaluation and in-silico docking studies

      Rasool, N., Razzaq, Z., Gul Khan, S., Javaid, S., Akhtar, N., Mahmood, S., Christensen, Jørn Bolstad, Ali Altaf, A., Muhammad Muneeb Anjum, S., Alqahtani, F., AlAsmari, A. F. & Imran, I., 2023, In: Arabian Journal of Chemistry. 16, 4, 14 p., 104610.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Mucoadhesive Dendrons Conjugated to Mesoporous Silica Nanoparticles as a Drug Delivery Approach for Orally Administered Biopharmaceuticals

      Tollemeto, M., Huang, Z., Christensen, Jørn Bolstad, Nielsen, Hanne Mørck & Rønholt, Stine, 2023, In: ACS Applied Materials and Interfaces. 15, 7, p. 8798–8810

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. 2022
    12. Published

      Interactions of Functionalized PAMAM Dendrimers with Model Cell Membranes Studied via Spin-Labeling Technique

      Carloni, R., Ottaviani, M. F., Ficker, M. & Christensen, Jørn Bolstad, 2022, In: Journal of Physical Chemistry B. 126, 46, p. 9686−9694 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Ultrasound Assisted Synthesis and In Silico Modelling of 1,2,4-Triazole Coupled Acetamide Derivatives of 2-(4-Isobutyl phenyl)propanoic acid as Potential Anticancer Agents

      Mahmood, S., Khan, S. G., Rasul, A., Christensen, Jørn Bolstad & Abourehab, M. A. S., Nov 2022, In: Molecules. 27, 22, 16 p., 7984.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Insight Into the Anti-staphylococcal Activity of JBC 1847 at Sub-Inhibitory Concentration

      Ronco, T., Kappel, L. H., Aragao, M. F., Biagi, N., Svenningsen, Søren Wedel, Christensen, Jørn Bolstad, Permin, A., Saaby, Lasse, Holmstrøm, K., Klitgaard, J. K., Sabat, A. J., Akkerboom, V., Monaco, M., Tinelli, M., Friedrich, A. W., Jana, B. & Olsen, Rikke Heidemann, 2022, In: Frontiers in Microbiology. 12, 786173.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. 2021
    16. Published

      Prediction of the standard potentials for one-electron oxidation of N,N,N',N' tetrasubstituted p-phenylenediamines by calculation

      Andersen, C. L., Lacerda Junior, E. G., Christensen, Jørn Bolstad, Sauer, Stephan P. A. & Hammerich, Ole, 22 Sep 2021, In: Physical Chemistry Chemical Physics. 23, 36, p. 20340–20351 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      A new donor for charge-transfer systems: synthesis and properties of 2,4,7,9-tetramethyl-1,6-dithiapyrene (TMDTP) and structure of (TMDTP)3(PF6)2·2THF and TMDTP–TCNQ

      Bendix, Jesper, Bechgaard, K. & Christensen, Jørn Bolstad, 2021, In: RSC Advances. 11, 24, p. 14607-14614 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      A new phenothiazine derivate is active against Clostridioides difficile and shows low cytotoxicity

      Ronco, T., Aragao, F. M., Saaby, Lasse, Christensen, Jørn Bolstad, Permin, A., Williams, Andrew Richard, Thamsborg, Stig Milan & Olsen, Rikke Heidemann, 2021, In: PLoS ONE. 16, 10, 13 p., e0258207.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Efficacy of a novel antimicrobial hydrogel for eradication of Staphylococcus epidermidis, Staphylococcus aureus and Cutibacterium acnes from preformed biofilm and treatment performance in an in vivo MRSA wound model

      Ronco, T., Aragao, M. F., Svenningsen, Søren Wedel, Christensen, Jørn Bolstad, Permin, A., Saaby, Lasse, Bionda, N., Lantz, E. E. & Olsen, Rikke Heidemann, 2021, In: JAC-Antimicrobial Resistance. 3, 3, 7 p., dlab108.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Dendrimer end-terminal motif-dependent evasion of human complement and complement activation through IgM hitchhiking

      Wu, L. P., Ficker, M., Christensen, Jørn Bolstad, Simberg, D., Trohopoulos, P. N. & Moghimi, S. M., Dec 2021, In: Nature Communications. 12, 1, 13 p., 4858.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. 2020
    22. Published

      Dendrimers for pharmaceutical applications - potential and challenges

      Christensen, Jørn Bolstad, 2020, Delivery of Drugs: Expectations and Realities of Multifunctional Drug Delivery Systems. Shegokar, R. (ed.). 1 ed. Amsterdam: Elsevier, Vol. 2. p. 29-54 24 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    23. Published

      Poly(lysine) Dendrimers and Other Dendritic Molecules From Naturally Occurring Monomers

      Christensen, Jørn Bolstad & Boas, U., 28 May 2020, Dendrimer Chemistry: Synthetic Approaches Towards Complex Architectures . Malkoch, M. & Gallego, S. G. (eds.). 1 ed. Royal Society of Chemistry, p. 58-84 27 p. (Monographs in Supramolecular Chemistry).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    24. Published

      A novel derivative of thioridazine shows low toxicity and efficient activity against gram‐positive pathogens

      Jørgensen, N. S., Saaby, Lasse, Andersson, A. M., Kromann, Sofie, Sheikhsamani, E., Permin, A., Ronco, T., Svenningsen, Søren Wedel, Christensen, Jørn Bolstad & Olsen, Rikke Heidemann, 2020, In: Antibiotics. 9, 6, 11 p., 327.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      A Novel Promazine Derivative Shows High in vitro and in vivo Antimicrobial Activity Against Staphylococcus aureus

      Ronco, T., Jørgensen, N. S., Holmer, I., Kromann, Sofie, Sheikhsamani, E., Permin, A., Svenningsen, Søren Wedel, Christensen, Jørn Bolstad & Olsen, Rikke Heidemann, 2020, In: Frontiers in Microbiology. 11, 12 p., 560798.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      Synthesis and Antimicrobial Properties of a Ciprofloxacin and PAMAM-dendrimer Conjugate

      Svenningsen, Søren Wedel, Frederiksen, R. F., Counil, C., Ficker, M., Leisner, Jørgen & Christensen, Jørn Bolstad, 2020, In: Molecules. 25, 6, p. 1-13 1389.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. 2019
    28. Published

      Pyrrolidone-modified PAMAM dendrimers enhance anti-inflammatory potential of indomethacin in vitro

      Gorzkiewicz, M., Janaszewska, A., Ficker, M., Svenningsen, Søren Wedel, Christensen, Jørn Bolstad & Klajnert-Maculewicz, B., 2019, In: Colloids and Surfaces B: Biointerfaces. 181, p. 959-962

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. 2018
    30. Published

      Bach Goes to Town

      Christensen, Jørn Bolstad, 2018, In: Biomolecules. 8, 3, 6 p., 75.

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. Published

      Dendrimers-based nanoparticles for cancer therapy and bioimaging

      Christensen, Jørn Bolstad, 2018, Nanooncology: Engineering Nanomaterials for Cancer Therapy and Diagnosis. Goncalves, G. & Tobias, G. (eds.). Cham: Springer, p. 281-304 24 p. (Nanomedicine and Nanotoxicology).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    32. Published

      Complexes of Indomethacin with 4-Carbomethoxy-pyrrolidone PAMAM Dendrimers Show Improved Anti-Inflammatory Properties and Temperature Dependent Binding and Release Profile

      Ficker, M., Theeuwen Matthijs, J. M., Janaszewska, A., Gorzkiewicz, M., Svenningsen, Søren Wedel, Klajnert-Maculewicz, B. & Christensen, Jørn Bolstad, 2018, In: Molecular Pharmaceutics. 15, 8, p. 3573-3582 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published

      Inexpensive and rapid hydrogenation catalyst from CuSO4/CoCl2 - Chemoselective reduction of alkenes and alkynes in the presence of benzyl protecting groups

      Ficker, M., Svenningsen, Søren Wedel, Larribeau, T. & Christensen, Jørn Bolstad, 2018, In: Tetrahedron Letters. 59, 12, p. 1125-1129 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. Published

      Pyrrolidone Modification Prevents PAMAM Dendrimers from Activation of Pro-Inflammatory Signaling Pathways in Human Monocytes

      Janaszewska, A., Gorzkiewicz, M., Ficker, M., Petersen, J. F., Paolucci, V., Christensen, Jørn Bolstad & Klajnert-Maculewicz, B., 2018, In: Molecular Pharmaceutics. 15, 1, p. 12-20 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    35. Published

      Comparison of Antibacterial Activity of (–) Thioridazine and Racemic Thioridazine in Staphylococcus aureus

      Poulsen, M. Ø., Klitgaard, J. K., Christensen, Jørn Bolstad, Kallipolitis, B. H., Kaatz, G. W., Plenge, P., Fey, S. J. & Kristiansen, J. E., 2018, In: American Journal of Bioavailability & Bioequivalence. 1, 1, p. 1-9 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. 2017
    37. Published

      Improved large-scale synthesis and characterization of small and medium generation PAMAM dendrimers

      Ficker, M., Paolucci, V. & Christensen, Jørn Bolstad, 2017, In: Canadian Journal of Chemistry. 95, 9, p. 954-964 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    38. Published

      Redemitting BODIPY boronic acid fluorescent sensors for detection of lactate

      Hansen, J. S., Hoeg-Jensen, T. & Christensen, Jørn Bolstad, 2017, In: Tetrahedron. 73, 21, p. 3010-3013 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. Published

      Modified PAMAM dendrimer with 4-carbomethoxypyrrolidone surface groups-its uptake, efflux, and location in a cell

      Janaszewska, A., Studzian, M., Petersen, J. F., Ficker, M., Paolucci, V., Christensen, Jørn Bolstad, Tomalia, D. A. & Klajnert-Maculewicz, B., 2017, In: Colloids and Surfaces B: Biointerfaces. 159, p. 211-216 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    40. Published

      Poly-(amidoamine) dendrimers with a precisely core positioned sulforhodamine B molecule for comparative biological tracing and profiling

      Wu, L., Ficker, M., Mejlsøe, S. L., Hall, A., Paolucci, V., Christensen, Jørn Bolstad, Trohopoulos, P. N. & Moghimi, S. M., 2017, In: Journal of Controlled Release. 246, p. 88-97 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. 2016
    42. Published

      Grundlæggende kemi

      Christensen, Jørn Bolstad, Jensen, F., Thaulov Andersen, J. E. & Hazell, R., 2016, 1. ed. Gyldendal. 482 p.

      Research output: Book/ReportBookEducation

    43. Published

      Photophysical properties of fluorescent core dendrimers controlled by size

      Paolucci, V., Mejlsøe, S. L., Ficker, M., Vosch, Tom & Christensen, Jørn Bolstad, 2016, In: The Journal of Physical Chemistry Part B. 120, 36, p. 9576-9580 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    44. Published

      Two for the price of one: PAMAM-dendrimers with mixed phosphoryl choline and oligomeric poly(caprolactone) surfaces

      Svenningsen, Søren Wedel, Janaszewska, A., Ficker, M., Petersen, J. F., Klajnert-Maculewicz, B. & Christensen, Jørn Bolstad, 2016, In: Bioconjugate Chemistry. 27, 6, p. 1547-1557 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. 2015
    46. Published

      Being two is better than one-catalytic reductions with dendrimer encapsulated copper- and copper-cobalt-subnanoparticles

      Ficker, M., Petersen, J. F., Gschneidtner, T., Rasmussen, A., Purdy, T., Hansen, J. S., Hansen, Thomas Hesselhøj, Husted, Søren, Poulsen, K. M., Olsson, E. & Christensen, Jørn Bolstad, 2015, In: Chemical Communications. 51, 49, p. 9957-9960 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. Published

      Guest-host chemistry with dendrimers—binding of carboxylates in aqueous solution

      Ficker, M., Petersen, J. F., Hansen, J. S. & Christensen, Jørn Bolstad, 2015, In: PloS one. 10, 10, 12 p., e0138706.

      Research output: Contribution to journalJournal articleResearchpeer-review

    48. Published

      PAMAM dendrimer with 4-carbomethoxypyrrolidone - In vitro assessment of neurotoxicity

      Janaszewska, A., Studzian, M., Petersen, J. F., Ficker, M., Christensen, Jørn Bolstad & Klajnert-Maculewicz, B., 2015, In: Nanomedicine: Nanotechnology, Biology and Medicine. 11, 2, p. 409-411 3 p.

      Research output: Contribution to journalLetterResearchpeer-review

    49. Published

      Adaptation of rabbit ventricular cell model to reproduce action potentials in isolated papillary muscle

      Jensen, A. S., Pennisi, C. P., Sevcencu, C., Christensen, Jørn Bolstad, Kristiansen, J. E. & Struijk, J. J., 16 Feb 2015, Computing in Cardiology Conference 2015, CinC 2015. Murray, A. (ed.). IEEE Computer Society Press, p. 429-432 4 p. 7408678. (Computing in Cardiology, Vol. 42).

      Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

    50. Model-based analysis of the effects of thioridazine enantiomers on the rabbit papillary action potential

      Jensen, A. S., Pennisi, C. P., Sevcencu, C., Christensen, Jørn Bolstad, Kristiansen, J. E. & Struijk, J. J., 16 Feb 2015, Computing in Cardiology Conference 2015, CinC 2015. Murray, A. (ed.). IEEE Computer Society Press, p. 1089-1092 4 p. 7411104. (Computing in Cardiology, Vol. 42).

      Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

    51. Published

      Differential effects of thioridazine enantiomers on action potential duration in rabbit papillary muscle

      Jensen, A. S., Pennisi, C. P., Sevcencu, C., Christensen, Jørn Bolstad, Kristiansen, J. E. & Struijk, J. J., 15 Jan 2015, In: European Journal of Pharmacology. 747, p. 7-12 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    52. Published

      Phenothiazines as a solution for multidrug resistant tuberculosis: from the origin to present

      Kristiansen, J. E., Dastidar, S. G., Palchoudhuri, S., Roy, D. S., Das, S., Hendricks, O. & Christensen, Jørn Bolstad, 2015, In: International Microbiology. 18, 1, p. 1-12 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    53. Published

      Synthesis and properties of chiral internally branched PAMAM-dendrimers

      Petersen, J. F., Tortzen, C., Pittelkow, Michael & Christensen, Jørn Bolstad, 2015, In: Tetrahedron. 71, 7, p. 1109-1116 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    54. Published

      Dendrimers in Medicine: therapeutic concepts and pharmaceutical challenges

      Wu, L., Ficker, M., Christensen, Jørn Bolstad, Trohopoulos, P. N. & Moghimi, S. M., 2015, In: Bioconjugate Chemistry. 26, 7, p. 1198-1211 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    55. 2014
    56. Published

      4,8-bisallyl-2,6-dimethylnaphthalene-1,5-diyl diacetate

      Christensen, Jørn Bolstad, Sørensen, J. N., Schaumburg, K. & Bechgaard, K., 2014, In: Molbank. 2014, 1, 4 p., M812.

      Research output: Contribution to journalJournal articleResearchpeer-review

    57. Published

      Hydrogenation of aromatic nitro compounds with an inexpensive and efficient CuSO4/CoCl2 catalyst prepared in situ using NaBH4 as the hydrogen source

      Ficker, M., Petersen, J. F., Hansen, J. S. & Christensen, Jørn Bolstad, 2014, In: Organic Preparations and Procedures International. 46, 2, p. 176-182 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    58. Published

      Synthesis and characterization of geminally dialkylsubstituted Tetraindanotetraoxa[8]circulenes

      Mejlsøe, S. L. & Christensen, Jørn Bolstad, 2014, In: Journal of Heterocyclic Chemistry. 51, 4, p. 1051-1057 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    59. 2013
    60. Published

      A comparative analysis of In vitro and In vivo efficacies of the enantiomers of thioridazine and its racemate

      Christensen, Jørn Bolstad, Hendricks, O., Chaki, S., Mukherjee, S., Das, A., Pal, T. K., Dastidar, S. G. & Kristiansen, J. E., 2013, In: P L o S One. 8, 3, 6 p., e57493.

      Research output: Contribution to journalJournal articleResearchpeer-review

    61. Published

      Dendrimers in biology and nanomedicine

      Christensen, Jørn Bolstad, 25 Oct 2013, Organic Synthesis and Molecular Engineering. Wiley-Interscience, p. 361-392 32 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    62. Published

      Effect of thioridazine stereoisomers on the drug accumulation of mouse lymphoma and human prostate cancer cell lines in vitro

      Csonka, Á., Spengler, G., Martins, A., Ocsovszki, I., Christensen, Jørn Bolstad, Hendricks, O., Kristiansen, J. E., Amaral, L. & Molnar, J., 2013, In: In Vivo. 27, 6, p. 815-20 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

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