Oluf Borbye Pedersen

Oluf Borbye Pedersen

Visiting professor, Clinical Professor

Member of:

  • Internal medicine: infection medicine

  • Internal Medicine: Endocrinology

ORCID: 0000-0002-3321-3972

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  1. Published

    A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads

    Rose, C. S., Grarup, Niels, Krarup, N. T., Poulsen, P., Wegner, L., Nielsen, T., Banasik, Karina, Faerch, K., Andersen, G., Albrechtsen, Anders, Borch-Johnsen, K., Clausen, J. O., Jørgensen, T., Vaag, Allan, Pedersen, Oluf Borbye & Hansen, Torben, 2009, In: Diabetologia. 52, 10, p. 2122-2129 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk

    Bouatia-Naji, N., Bonnefond, A., Cavalcanti-Proença, C., Sparsø, T., Holmkvist, J., Marchand, M., Delplanque, J., Lobbens, S., Rocheleau, G., Durand, E., De Graeve, F., Chèvre, J-C., Borch-Johnsen, K., Hartikainen, A-L., Ruokonen, A., Tichet, J., Marre, M., Weill, J., Heude, B., Tauber, M. & 21 others, Lemaire, K., Schuit, F., Elliott, P., Jørgensen, T., Charpentier, G., Hadjadj, S., Cauchi, S., Vaxillaire, M., Sladek, R., Visvikis-Siest, S., Balkau, B., Lévy-Marchal, C., Pattou, F., Meyre, D., Blakemore, A. I. F., Jarvelin, M., Walley, A. J., Hansen, Torben, Dina, C., Pedersen, Oluf Borbye & Froguel, P., 2009, In: Nature Genetics. 41, 1, p. 89-94 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    ADAMTS9 regulates skeletal muscle insulin sensitivity through extracellular matrix alterations

    Graae, A-S., Grarup, N., Ribel-Madsen, R., Lystbæk, S. H., Boesgaard, T., Staiger, H., Fritsche, A., Wellner, N., Sulek, K., Kjølby, M. F., Backe, M. B., Chubanava, S., Prats, C., Serup, A. K. L., Birk, J. B., Dubail, J., Gillberg, L., Vienberg, S. G., Nykjær, A., Kiens, B. & 10 others, Wojtaszewski, Jørgen F P, Larsen, Steen, Apte, S. S., Häring, H., Vaag, A., Zethelius, B., Pedersen, Oluf Borbye, Treebak, Jonas Thue, Hansen, Torben & Holst, Birgitte, 2019, In: Diabetes. 68, 3, p. 502-514

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    AHSG tag single nucleotide polymorphisms associate with type 2 diabetes and dyslipidemia: studies of metabolic traits in 7,683 white Danish subjects

    Andersen, G., Burgdorf, K. S., Sparsø, T., Borch-Johnsen, K., Jørgensen, T., Hansen, T. & Pedersen, Oluf Borbye, 2008, In: Diabetes. 57, 5, p. 1427-32 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Abdominal adiposity and cardiometabolic risk factors in children and adolescents: A Mendelian randomization analysis

    Viitasalo, A., Schnurr, T. M., Pitkänen, N., Hollensted, M., Nielsen, T. R. H., Pahkala, K., Atalay, M., Lind, M. V., Heikkinen, S., Frithioff-Bøjsøe, C., Fonvig, C. E., Grarup, N., Kähönen, M., Carrasquilla, G. D., Larnkjær, A., Pedersen, O., Michaelsen, K. F., Lakka, T. A., Holm, J-C., Lehtimäki, T. & 3 others, Raitakari, O., Hansen, Torben & Kilpeläinen, Tuomas O., 2019, In: American Journal of Clinical Nutrition. 110, 5, p. 1079-1087 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents

    Wang, X., Yang, S., Li, S., Zhao, L., Hao, Y., Qin, J., Zhang, L., Zhang, C., Bian, W., Zuo, L. I., Gao, X., Zhu, B., Lei, X., Gu, Z., Cui, W., Xu, X., Li, Z., Zhu, B., Li, Y., Chen, S. & 24 others, Guo, H., Zhang, H., Sun, Jing, Zhang, M., Hui, Y., Zhang, X., Liu, X., Sun, B., Wang, L., Qiu, Q., Zhang, Y., Li, X., Liu, W., Xue, R., Wu, H., Shao, D., Li, J., Zhou, Y., Li, S., Yang, R., Pedersen, Oluf Borbye, Yu, Z., Ehrlich, S. D. & Ren, F., 2020, In: Gut. 69, 12, p. 2131-2142 319766.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Aberrant intestinal microbiota in individuals with prediabetes

    Allin, K. H., Tremaroli, V., Caesar, R., Jensen, Benjamin Anderschou Holbech, Damgaard, Mads Vargas, Bahl, M. I., Licht, T. R., Hansen, T. H., Nielsen, T., Dantoft, T. M., Linneberg, Allan René, Jørgensen, T., drb459, drb459, Kristiansen, Karsten, Franks, P. W., IMI-DIRECT consortium, I. C., Hansen, Torben, Bäckhed, G. F. & Pedersen, Oluf Borbye, Apr 2018, In: Diabetologia. 61, 4, p. 810-820 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Accurate genotyping across variant classes and lengths using variant graphs

    Sibbesen, Jonas Andreas, Maretty, L., Krogh, Anders, Petersen, Bent, Sibbesen, Jonas Andreas, Liu, S., Have, C. T., Bork-Jensen, J., Guo, X., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Wang, J. & Brunak, Søren, 2018, In: Nature Genetics. 50, p. 1054-1059 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Affective disorders and high familial risk of affective disorders associate with aberrant intestinal microbiota

    Vinberg, Maj, Ottesen, N., Meluken, I., Sørensen, N., Pedersen, Oluf Borbye, Kessing, Lars Vedel & Miskowiak, Kamilla, 2019, In: European Neuropsychopharmacology. 29, Suppl. 1, p. S51 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  10. Published

    Affective disorders impact prevalence of Flavonifractor and abundance of Christensenellaceae in gut microbiota

    Coello, K., Hansen, T. H., Sørensen, N., Ottesen, N. M., Miskowiak, Kamilla, Pedersen, Oluf Borbye, Kessing, Lars Vedel & Vinberg, Maj, 2021, In: Progress in Neuro-Psychopharmacology and Biological Psychiatry. 110, 110300.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Alcohol consumption and its interaction with adiposity-associated genetic variants in relation to subsequent changes in waist circumference and body weight

    Rohde, J. F., Ängquist, Lars, Larsen, S. C., Tolstrup, J. S., Husemoen, L. L. N., Linneberg, Allan René, Toft, Ulla Marie Nørgaard, Overvad, K., Halkjær, J., Tjønneland, A., Hansen, Torben, Pedersen, Oluf Borbye, Sørensen, Thorkild I.A. & Heitmann, Berit, 25 Aug 2017, In: Nutrition Journal. 16, 11 p., 51.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Allelic variants of melanocortin 3 receptor gene (MC3R) and weight loss in obesity: a randomised trial of hypo-energetic high- versus low-fat diets

    L. Santos, J., De la Cruz, R., Holst, C., Grau, K., Naranjo, C., Maiz, A., Astrup, A., Saris, W. H. M., MacDonald, I., Oppert, J., Hansen, T., Pedersen, Oluf Borbye, Sørensen, Thorkild I.A., Martinez, J. A. & NUGENOB Consortium, 2011, In: P L o S One. 6, 6, p. e199934 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Alteration of Gut Microbiome in Patients With Schizophrenia Indicates Links Between Bacterial Tyrosine Biosynthesis and Cognitive Dysfunction

    Thirion, F., Speyer, H., Hansen, T. H., Nielsen, T., Fan, Y., Le Chatelier, E., Fromentin, S., Berland, M., Plaza Oñate, F., Pons, N., Galleron, N., Levenez, F., Markó, L., Birkner, T., Jørgensen, T., Forslund, S. K., Vestergaard, H., Hansen, T., Nordentoft, M., Mors, O. & 3 others, Benros, Michael Eriksen, Pedersen, Oluf Borbye & Ehrlich, S. D., 2023, In: Biological Psychiatry Global Open Science. 3, 2, p. 283-291 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Alterations in fecal microbiota composition by probiotic supplementation in healthy adults: a systematic review of randomized controlled trials

    Kristensen, N. B., Bryrup, T., Allin, K. H., Nielsen, T., Hansen, T. H. & Pedersen, Oluf Borbye, 2016, In: Genome Medicine. 8, 1, 11 p., 52.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Altered Glucagon and GLP-1 Responses to Oral Glucose in Children and Adolescents With Obesity and Insulin Resistance

    Stinson, Sara, Fernández de Retana Alzola, I., Hovendal, Emilie Damgaard Brünner, Lund, Morten Asp Vonsild, Fonvig, Cilius Esmann, Holm, Louise Aas, Jonsson, Anna Elisabet, Frithioff-Bøjsøe, C., Christiansen, Michael, Pedersen, Oluf Borbye, Ängquist, Lars, Sørensen, T. I. A., Holst, Jens Juul, Hartmann, Bolette, Holm, Jens-Christian & Hansen, Torben, 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 6, p. 1590-1600 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Alternative splicing of exon 17 and a missense mutation in exon 20 of the insulin receptor gene in two brothers with a novel syndrome of insulin resistance (congenital fiber-type disproportion myopathy)

    Vorwerk, P., Christoffersen, C. T., Müller, J., drb459, drb459, Pedersen, Oluf Borbye, De Meyts, P. & drb459, drb459, 1999, In: Hormone Research. 52, 5, p. 211-20 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus

    Almind, K., Bjørbaek, C., drb459, drb459, Hansen, Torben, Echwald, S. M. & Pedersen, Oluf Borbye, 2 Oct 1993, In: Lancet. 342, 8875, p. 828-32 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

    Scott, R. A., Scott, L. J., Mägi, R., Marullo, L., Gaulton, K. J., Kaakinen, M., Pervjakova, N., Pers, T. H., Johnson, A. D., Eicher, J. D., Jackson, A. U., Ferreira, T., Lee, Y., Ma, C., Steinthorsdottir, V., Thorleifsson, G., Qi, L., Van Zuydam, N. R., Mahajan, A., Chen, H. & 155 others, Almgren, P., Voight, B. F., Grallert, H., Müller-Nurasyid, M., Ried, J. S., Rayner, W. N., Robertson, N., Karssen, L. C., van Leeuwen, E. M., Willems, S. M., Fuchsberger, C., Kwan, P., Teslovich, T. M., Chanda, P., Li, M., Lu, Y., Dina, C., Thuillier, D., Yengo, L., Jiang, L., Sparso, T., Kestler, H. A., Chheda, H., Eisele, L., Gustafsson, S., Frånberg, M., Strawbridge, R. J., Benediktsson, R., Hreidarsson, A. B., Kong, A., Sigurðsson, G., Kerrison, N. D., Luan, J., Liang, L., Meitinger, T., Roden, M., Thorand, B., Esko, T., Mihailov, E., Fox, C., Liu, C., Rybin, D., Isomaa, B., Lyssenko, V., Tuomi, T., Couper, D. J., Pankow, J. S., Grarup, Niels, Have, C. T., Jørgensen, M. E., Jørgensen, T., Linneberg, Allan René, Cornelis, M. C., van Dam, R. M., Hunter, D. J., Kraft, P., Sun, Q., Edkins, S., Owen, K. R., Perry, J. R., Wood, A. R., Zeggini, E., Tajes-Fernandes, J., Abecasis, G. R., Bonnycastle, L. L., Chines, P. S., Stringham, H. M., Koistinen, H. A., Kinnunen, L., Sennblad, B., Mühleisen, T. W., Nöthen, M. M., Pechlivanis, S., Baldassarre, D., Gertow, K., Humphries, S. E., Tremoli, E., Klopp, N., Meyer, J., Steinbach, G., Wennauer, R., Eriksson, J. G., Mӓnnistö, S., Peltonen, L., Tikkanen, E., Charpentier, G., Eury, E., Lobbens, S., Gigante, B., Leander, K., McLeod, O., Bottinger, E. P., Gottesman, O., Ruderfer, D., Blüher, M., Kovacs, P., Tonjes, A., Maruthur, N. M., Scapoli, C., Erbel, R., Jöckel, K., Moebus, S., de Faire, U., Hamsten, A., Stumvoll, M., Deloukas, P., Donnelly, P. J., Frayling, T. M., Hattersley, A. T., Ripatti, S., Salomaa, V., Pedersen, N. L., Boehm, B. O., Bergman, R. N., Collins, F. S., Mohlke, K. L., Tuomilehto, J., Hansen, Torben, Pedersen, Oluf Borbye, Barroso, I., Lannfelt, L., Ingelsson, E., Lind, L., Lindgren, C. M., Cauchi, S., Froguel, P., Loos, R. J., Balkau, B., Boeing, H., Franks, P. W., Gurrea, A. B., Palli, D., van der Schouw, Y. T., Altshuler, D., Groop, L. C., Langenberg, C., Wareham, N. J., Sijbrands, E., van Duijn, C. M., Florez, J. C., Meigs, J. B., Boerwinkle, E., Gieger, C., Strauch, K., Metspalu, A., Morris, A. D., Palmer, C. N., Hu, F. B., Thorsteinsdottir, U., Stefansson, K., Dupuis, J., Morris, A. P., Boehnke, M., McCarthy, M. I. & Prokopenko, I., 2017, In: Diabetes. 66, 11, p. 2888-2902

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    An Improved Method for High Quality Metagenomics DNA Extraction from Human and Environmental Samples

    Bag, S., Saha, B., Mehta, O., Anbumani, D., Kumar, N., Dayal, M., Pant, A., Kumar, P., Saxena, S., Allin, K. H., Hansen, T., Arumugam, M., Vestergaard, H., Pedersen, O., Pereira, V., Abraham, P., Tripathi, R., Wadhwa, N., Bhatnagar, S., Prakash, V. G. & 7 others, Radha, V., Anjana, R. M., Mohan, V., Takeda, K., Kurakawa, T., Nair, G. B. & Das, B., 2016, In: Scientific Reports. 6, 9 p., 26775.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    An adult-based genetic risk score for hepatic fat associates with liver and lipid traits in Danish children and adolescents

    Huang, Yun, Stinson, Sara, Juel, H. B., Lund, Morten Asp Vonsild, Holm, L. A., Fonvig, Cilius Esmann, Grarup, Niels, Pedersen, Oluf Borbye, Christiansen, Michael, Krag, A., Stender, S., Holm, Jens-Christian & Hansen, Torben, 2022, In: Journal of Hepatology. 77, p. S450-S450 1 p., FRI104.

    Research output: Contribution to journal › Conference abstract in journal › Research

  21. Published

    An adult-based genetic risk score for liver fat associates with liver and plasma lipid traits in children and adolescents

    Huang, Yun, Stinson, Sara, Juel, H. B., Lund, M. A. V., Holm, Louise Aas, Fonvig, Cilius Esmann, Nielsen, T., Grarup, Niels, Pedersen, Oluf Borbye, Christiansen, M., Chabanova, E., Thomsen, Henrik S., Krag, A., Stender, S., Holm, Jens-Christian & Hansen, Torben, 2023, In: Liver International. 43, 8, p. 1772-1782 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    An adult-based insulin resistance genetic risk score associates with insulin resistance, metabolic traits and altered fat distribution in Danish children and adolescents who are overweight or obese

    Graae, A. S., Hollensted, M., Kloppenborg, J. T., Mahendran, Y., Schnurr, T. M., Appel, E. V. R., Rask, J., Nielsen, T. R. H., Johansen, M., Linneberg, Allan René, Jørgensen, M. E., Grarup, Niels, Kadarmideen, H. N., Holst, Birgitte, Pedersen, Oluf Borbye, Holm, Jens-Christian & Hansen, Torben, Aug 2018, In: Diabetologia. 61, 8, p. 1769-1779

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    An integrated catalog of reference genes in the human gut microbiome

    Li, J., Jia, H., Cai, X., Zhong, H., Feng, Q., Sunagawa, S., Arumugam, M., Kultima, J. R., Prifti, E., Nielsen, T., Juncker, A., Manichanh, C., Chen, B., Zhang, W., Levenez, F., Wang, J., Xu, X., Xiao, L., Liang, S., Zhang, D. & 17 others, Zhang, Z., Chen, W., Zhao, H., Al-Aama, J. Y., Edris, S., Yang, H., Wang, J., Hansen, Torben, Nielsen, H. B., Brunak, S., Kristiansen, Karsten, Guarner, F., Pedersen, Oluf Borbye, Doré, J., Ehrlich, S. D., Bork, P. & Wang, J., 2014, In: Nature Biotechnology. 32, 8, p. 834-845 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Analysis of 62 hybrid assembled human Y chromosomes exposes rapid structural changes and high rates of gene conversion

    Skov, L., Schierup, M. H., Danish Pan Genome Consortium, D. P. G. C., Sørensen, L. M., Petersen, Bent, Sibbesen, Jonas Andreas, Liu, S., Belling, K. G., Have, C. T., Bork-Jensen, J., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Rasmussen, Simon, Kristiansen, Karsten & Brunak, Søren, 2017, In: PLOS Genetics. 13, 8, p. e1006834

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism

    Helgadottir, A., Gretarsdottir, S., Thorleifsson, G., Holm, H., Patel, R. S., Gudnason, T., Jones, G. T., van Rij, A. M., Eapen, D. J., Baas, A. F., Tregouet, D-A., Morange, P-E., Emmerich, J., Lindblad, B., Gottsäter, A., Kiemeny, L. A., Lindholt, J. S., Sakalihasan, N., Ferrell, R. E., Carey, D. J. & 63 others, Elmore, J. R., Tsao, P. S., Grarup, Niels, Jørgensen, T., Witte, D. R., Hansen, Torben, Pedersen, Oluf Borbye, Pola, R., Gaetani, E., Magnadottir, H. B., Wijmenga, C., Tromp, G., Ronkainen, A., Ruigrok, Y. M., Blankensteijn, J. D., Mueller, T., Wells, P. S., Corral, J., Soria, J. M., Souto, J. C., Peden, J. F., Jalilzadeh, S., Mayosi, B. M., Keavney, B., Strawbridge, R. J., Sabater-Lleal, M., Gertow, K., Baldassarre, D., Nyyssönen, K., Rauramaa, R., Smit, A. J., Mannarino, E., Giral, P., Tremoli, E., de Faire, U., Humphries, S. E., Hamsten, A., Haraldsdottir, V., Olafsson, I., Magnusson, M. K., Samani, N. J., Levey, A. I., Markus, H. S., Kostulas, K., Dichgans, M., Berger, K., Kuhlenbäumer, G., Ringelstein, E. B., Stoll, M., Seedorf, U., Rothwell, P. M., Powell, J. T., Kuivaniemi, H., Onundarson, P. T., Valdimarsson, E., Matthiasson, S. E., Gudbjartsson, D. F., Thorgeirsson, G., Quyyumi, A. A., Watkins, H., Farrall, M., Thorsteinsdottir, U. & Stefansson, K., 2012, In: Journal of the American College of Cardiology. 60, 8, p. 722-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 919113