Hans Bräuner

Hans Bräuner

Prodekan for forskning


  1. Published

    Design, synthesis, and pharmacological characterization of novel, potent NMDA receptor antagonists

    Conti, P., De Amici, M., Grazioso, G., Roda, G., Barberis Negra, F. F., Nielsen, Birgitte, Stensbøl, T. B., Madsen, Ulf, Bräuner, Hans, Frydenvang, Karla Andrea, De Sarro, G., Toma, L. & De Micheli, C., 30 Dec 2004, In: Journal of Medicinal Chemistry. 47, 27, p. 6740-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Design, synthesis, and pharmacology of a highly subtype-selective GluR1/2 agonist, (RS)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid (Cl-HIBO)

    Bjerrum, E. J., Kristensen, Anders Skov, Pickering, D. S., Greenwood, J. R., Nielsen, Birgitte, Liljefors, T., Schousboe, Arne, Bräuner, Hans, Madsen, Ulf & Pickering, Darryl S, 2003, In: Journal of Medicinal Chemistry. 46, 11, p. 2246-9 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Detailed characterization of the in vitro pharmacological and pharmacokinetic properties of N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine (25CN-NBOH), a highly selective and brain-penetrant 5-HT2A receptor agonist

    Jensen, Anders A., McCorvy, J. D., Petersen, S. L., Bundgaard, C., Liebscher, G., Kenakin, T. P., Bräuner, Hans, Kehler, J. & Kristensen, Jesper Langgaard, 2017, In: Journal of Pharmacology and Experimental Therapeutics. 361, 3, p. 441-453

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Detailed in vitro pharmacological characterization of clinically tested negative allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5)

    Arsova, A., Møller, T. C., Vedel, L., Hansen, J. L., Foster, S. R., Gregory, K. J. & Bräuner, Hans, 2020, In: Molecular Pharmacology. 98, 1, p. 49-60

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Development of a medium throughput whole-cell microtiter plate Thr286 autophosphorylation assay for CaMKIIα using ELISA

    Palmelund, L. B., van Woerden, G. M., Bräuner, Hans & Wellendorph, Petrine, 2022, In: Journal of Pharmacological and Toxicological Methods. 118, 8 p., 107226.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Different domains of the glucagon and glucagon-like peptide-1 receptors provide the critical determinants of ligand selectivity

    Runge, S., Wulff, B. S., Madsen, K., Bräuner, Hans & Knudsen, L. B., Mar 2003, In: British Journal of Pharmacology. 138, 5, p. 787-94

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Accepted/In press

    Differential G protein activation by the long and short isoforms of the dopamine D2 receptor

    Reiner-Link, David, Madsen, Jakob Sture, Gloriam, David E., Bräuner, Hans & Hauser, Alexander Sebastian, 2024, (Accepted/In press) In: British Journal of Pharmacology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Differential compartmentalization and distinct functions of GABAB receptor variants

    Vigot, R., Barbieri, S., Bräuner, Hans, Turecek, R., Shigemoto, R., Zhang, Y., Luján, R., Jacobson, L. H., Biermann, B., Fritschy, J., Vacher, C., Müller, M., Sansig, G., Guetg, N., Cryan, J. F., Kaupmann, K., Gassmann, M., Oertner, T. G. & Bettler, B., 18 May 2006, In: Neuron. 50, 4, p. 589-601

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors

    Foster, S. R., Hauser, Alexander Sebastian, Vedel, L., Strachan, R. T., Huang, X., Gavin, A. C., Shah, S. D., Nayak, A. P., Haugaard-Kedström, L. M., Penn, R. B., Roth, B. L., Bräuner, Hans & Gloriam, David E., 31 Oct 2019, In: Cell. 179, 4, p. 895-908

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Discovery of a subtype-selective of the human betaine/GABA transporter 1 (BGT-1) with a non-competitive pharmacological profile

    Kragholm, B., Kvist, T., Madsen, K. K., Jørgensen, L., Vogensen, S. B., Schousboe, Arne, Clausen, Rasmus Prætorius, Jensen, Anders A. & Bräuner, Hans, 2013, In: Biochemical Pharmacology. 86, p. 521-528

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells

    Møller, T. C., Pedersen, M. F., van Senten, Jeffrey Roy, Seiersen, S. D., Mathiesen, Jesper M., Bouvier, M. & Bräuner, Hans, 2020, In: Scientific Reports. 10, 1, 13 p., 17395.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    En genetisk variation i en serotonin-receptor: et muligt link til depression?

    Krzywkowski, K. M., Davies, P. A., Feinberg-Zadek, P. L., Jensen, Anders A. & Bräuner, Hans, 2007, In: Lægemiddelforskning. p. 30-31

    Research output: Contribution to journalJournal articleCommunication

  13. Published

    En genetisk variation i en serotonin–receptor – et muligt link til depression?

    Krzywkowski, K. M., Feinberg-Zadek, P., Davies, P. A., Jensen, Anders A. & Bräuner, Hans, 2008, In: Dansk Kemi 83. 89, 6/7

    Research output: Contribution to journalJournal articleCommunication

  14. Published

    Endocytic proteins mediating GPR15 receptor internalization provide insight into the underlying mechanisms

    Deng, Y., Moo, Ee Von, Inoue, A. & Bräuner, Hans, 2023, In: FEBS Letters. 597, 11, p. 1528-1540

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Enhanced agonist residence time, internalization rate and signalling of the GIP receptor variant [E354Q] facilitate receptor desensitization and long-term impairment of the GIP system

    Gabe, M. B. N., van der Velden, W. J. C., Gadgaard, S., Smit, F. X., Hartmann, Bolette, Bräuner, Hans & Rosenkilde, Mette, 2020, In: Basic & Clinical Pharmacology & Toxicology. 126, p. 122-132

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Enhanced voluntary wheel running in GPRC6A receptor knockout mice

    Clemmensen, Christoffer, Pehmøller, C., Klein, A. B., Ratner, C., Wojtaszewski, Jørgen F P & Bräuner, Hans, 2013, In: Physiology & Behavior. 118, p. 144-151 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Erratum: Synthesis and pharmacology of glutamate receptor ligands: New isothiazole analogues of ibotenic acid (Organic and Biomolecular Chemistry (2007) 5 DOI:10.1039/b615162k)

    Jørgensen, Charlotte Grube, Clausen, Rasmus Prætorius, Hansen, K. B., Bräuner, Hans, Nielsen, Birgitte, Metzler, B., Kehler, J., Krogsgaard-Larsen, Povl & Madsen, Ulf, 2007, In: Organic and Biomolecular Chemistry. 5, 5, p. 848 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  18. Published

    Excitatory amino acid receptor ligands: resolution, absolute stereochemistry, and enantiopharmacology of 2-amino-3-(4-butyl-3-hydroxyisoxazol-5-yl)propionic acid

    Johansen, Tommy Nørskov, Ebert, B., Bräuner, Hans, Didriksen, M., Christensen, I. T., Søby, K. K., Madsen, Ulf, Krogsgaard-Larsen, Povl & Brehm, L., 12 Mar 1998, In: Journal of Medicinal Chemistry. 41, 6, p. 930-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors

    Rossol, M., Pierer, M., Raulien, N., Quandt, D., Meusch, U., Rothe, K., Schubert, K., Schöneberg, T., Schaefer, M., Krügel, U., Smajilovic, S., Bräuner, Hans, Baerwald, C. & Wagner, U., 2012, In: Nature Communications. 3, p. 1329

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    FLIPR assays of intracellular calcium in GPCR drug discovery

    Hansen, K. B. & Bräuner, Hans, 2009, G protein-coupled receptors in drug discovery. Leifert, W. R. (ed.). United States: Humana Press, Vol. 552. p. 269-278 (Methods in Molecular Biology, Vol. 552).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  21. Published

    Fluorescensbaseret farmakologi

    Jensen, Anders A., Strange, M. & Bräuner, Hans, 2004, In: Dansk Kemi 83. p. 29 31 p.

    Research output: Contribution to journalJournal articleCommunication

  22. Published

    Functional Consequences of Glucagon-like Peptide-1 Receptor Cross-talk and Trafficking

    Roed, S. N., Nøhr, A. C., Wismann, P., Iversen, H., Bräuner, Hans, Knudsen, S. M. & Waldhoer, M., 9 Jan 2015, In: The Journal of Biological Chemistry. 290, 2, p. 1233-1243 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Functional characterisation of homomeric ionotropic glutamate receptors GluR1-GluR6 in a fluorescence-based high throughput screening assay

    Strange, M., Bräuner, Hans & Jensen, Anders A., 2006, In: Combinatorial Chemistry & High Throughput Screening. 9, 2, p. 147-58 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Functional characterization of Tet-AMPA [tetrazolyl-2-amino-3-(3-hydroxy-5-methyl- 4-isoxazolyl)propionic acid] analogues at ionotropic glutamate receptors GluR1-GluR4. The molecular basis for the functional selectivity profile of 2-Bn-Tet-AMPA

    Jensen, Anders A., Christesen, T., Bølcho, U., Greenwood, J. R., Postorino, G., Vogensen, S. B., Johansen, Tommy Nørskov, Egebjerg, J., Bräuner, Hans & Clausen, Rasmus Prætorius, 2007, In: Journal of Medicinal Chemistry. 50, 17, p. 4177-4185 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Functional importance of the Ala(116)-Pro(136) region in the calcium-sensing receptor. Constitutive activity and inverse agonism in a family C G-protein-coupled receptor

    Jensen, Anders A., Spalding, T. A., Burstein, E. S., Sheppard, P. O., O'Hara, P. J., Brann, M. R., Krogsgaard-Larsen, Povl & Bräuner, Hans, 2000, In: Journal of Biological Chemistry. 275, 38, p. 29547-55 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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