Shohreh Issazadeh-Navikas
Professor
Issazadeh-Navikas Group
Ole Maaløes Vej 5
2200 København N.
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. Immunosuppressive FoxA1-expressing T cells.
Issazadeh-Navikas, Shohreh, 2015, Patent No. PA 2013 70820, WO 2015 097210Research output: Patent
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A loss-of-function screen for phosphatases that regulate neurite outgrowth identifies PTPN12 as a negative regulator of TrkB tyrosine phosphorylation
Ambjørn, M., Dubreuil, V., Miozzo, F., Nigon, F., Møller, B., Issazadeh-Navikas, Shohreh, Berg, J., Lees, M. & Sap, J., 2013, In: PloS one. 8, 6, p. e65371Research output: Contribution to journal › Journal article › Research › peer-review
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A mutation in DOP1B identified as a probable cause for autosomal recessive Peters anomaly in a consanguineous family
Darbari, E., Zare-Abdollahi, D., Alavi, A., Rezaei Kanavi, M., Feizi, S., Hosseini, S. B., Baradaran-Rafii, A., Ahmadieh, H., Issazadeh-Navikas, Shohreh & Elahi, E., 2020, In: Molecular Vision. 26, p. 757-765 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ADAM12 is a costimulatory molecule that determines Th1 cell fate and mediates tissue inflammation
Liu, Yawei, Bockermann, R., Hadi, M., Safari, Iman, Carrion, B., Kveiborg, Marie & Issazadeh-Navikas, Shohreh, 2021, In: Cellular & Molecular Immunology. 18, p. 1904-1919Research output: Contribution to journal › Journal article › Research › peer-review
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Acquired thymic tolerance: role of CTLA4 in the initiation and maintenance of tolerance in a clinically relevant autoimmune disease model.
Issazadeh-Navikas, Shohreh, Zhang, M., Sayegh, M. H. & Khoury, S. J., 1999, In: Journal of Immunology. 162, 2, p. 761-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Alerting the immune system via stromal cells is central to the prevention of tumor growth
Issazadeh-Navikas, Shohreh, 1 Dec 2013, In: OncoImmunology. 2, 12, p. e27091Research output: Contribution to journal › Journal article › Research › peer-review
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Angiotensinogen and HLA class II predict bevacizumab response in recurrent glioblastoma patients
Urup, T., Michaelsen, Signe Regner, Olsen, L. R., Toft, A., Christensen, I. J., Grunnet, K., Winther, Ole, Broholm, H., Kosteljanetz, M., Issazadeh-Navikas, Shohreh, Poulsen, H. S. & Lassen, Ulrik Niels, Oct 2016, In: Molecular Oncology. 10, 8, p. 1160-1168Research output: Contribution to journal › Journal article › Research › peer-review
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Antiinflammatory properties of a peptide derived from interleukin-4
Klementiev, B., Enevoldsen, M. N., Li, S., Carlsson, R., Liu, Yawei, Issazadeh-Navikas, Shohreh, Bock, E. & Berezin, V., Oct 2013, In: Cytokine. 64, 1, p. 112-21 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antiviral, Immunomodulatory and Antiproliferative Activities of Recombinant Soluble IFNAR2 without IFN-ß Mediation
Hurtado Guerrero, Isaac, Hernáez, B., Pinto-medel, M. J., Calonge, E., Rodriguez-bada, J. L., Urbaneja, P., Alonso, A., Mena-vázquez, N., Aliaga, P., Issazadeh-Navikas, Shohreh, Pavia, J., Leyva, L., Alcamí, J., Alcamí, A., Fernández, Ó. & Oliver-martos, B., 2020, In: Journal of Clinical Medicine. 9, 4, p. 959Research output: Contribution to journal › Journal article › Research › peer-review
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CD1-dependent regulation of chronic central nervous system inflammation in experimental autoimmune encephalomyelitis.
Teige, A., Teige, I., Lavasani, S., Bockermann, R., Mondoc, E., Holmdahl, R. & Issazadeh-Navikas, Shohreh, 2004, In: Journal of Immunology. 172, 1, p. 186-94 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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CD1d knockout mice exhibit aggravated contact hypersensitivity responses due to reduced interleukin-10 production predominantly by regulatory B cells
Fjelbye, J., Antvorskov, J. C., Buschard, K., Issazadeh-Navikas, Shohreh & Engkilde, K., Nov 2015, In: Experimental Dermatology Online. 24, 11, p. 853-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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CD1d-dependent NKT cells play a protective role in acute and chronic arthritis models by ameliorating antigen-specific Th1 responses
Teige, A., Bockermann, R., Hasan, M., Olofsson, K. E., Liu, Yawei & Issazadeh-Navikas, Shohreh, 2010, In: Journal of Immunology. 185, 1, p. 345-56 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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CHST6 mutations identified in Iranian MCD patients and CHST6 mutations reported worldwide identify targets for gene editing approaches including the CRISPR/Cas system
Safari, Iman, Baradaran-Rafii, A., Issazadeh-Navikas, Shohreh & Elahi, E., 2020, In: International Ophthalmology. 40, p. 2223-2235Research output: Contribution to journal › Journal article › Research › peer-review
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CSF SERPINA3 Levels Are Elevated in Patients With Progressive MS
Fissolo, N., Matute-Blanch, C., Osman, Mudi, Costa, C., Pinteac, R., Miró, B., Sanchez, A., Brito, V., Dujmovic, I., Voortman, M., Khalil, M., Borràs, E., Sabidó, E., Issazadeh-Navikas, Shohreh, Montalban, X. & Comabella Lopez, M., 2021, In: Neurology: Neuroimmunology & Neuroinflammation. 8, 2, 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Corrigendum: Neuronal IFN-beta-induced PI3K/Akt-FoxA1 signalling is essential for generation of FoxA1+Treg cells
Liu, Yawei, Marin, Andrea, Ejlerskov, P., Rasmussen, L. M., Prinz, M. & Issazadeh-Navikas, Shohreh, 2017, In: Nature Communications. 8, p. 15792 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Costimulatory signal blockade in murine relapsing experimental autoimmune encephalomyelitis.
Schaub, M., Issazadeh-Navikas, Shohreh, Stadlbauer, T. H., Peach, R., Sayegh, M. H. & Khoury, S. J., 1999, In: Journal of Neuroimmunology. 96, 2, p. 158-66 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cytokine production in the central nervous system of Lewis rats with experimental autoimmune encephalomyelitis: dynamics of mRNA expression for interleukin-10, interleukin-12, cytolysin, tumor necrosis factor alpha and tumor necrosis factor beta.
Issazadeh-Navikas, Shohreh, Ljungdahl, A., Höjeberg, B., Mustafa, M. & Olsson, T., 1995, In: Journal of Neuroimmunology. 61, 2, p. 205-12 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cytokines in relapsing experimental autoimmune encephalomyelitis in DA rats: persistent mRNA expression of proinflammatory cytokines and absent expression of interleukin-10 and transforming growth factor-beta.
Issazadeh-Navikas, Shohreh, Lorentzen, J. C., Mustafa, M. I., Höjeberg, B., Müssener, A. & Olsson, T., 1996, In: Journal of Neuroimmunology. 69, 1-2, p. 103-15 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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DNMT1 regulates expression of MHC class I in post-mitotic neurons
Gustafsson, J. R., Katsioudi, G., Degn, M., Ejlerskov, P., Issazadeh-Navikas, Shohreh & Kornum, Birgitte Rahbek, 2018, In: Molecular Brain. 11, 1, p. 1-16 16 p., 36.Research output: Contribution to journal › Journal article › Research › peer-review
Decreased severity of myelin oligodendrocyte glycoprotein peptide 33 - 35-induced experimental autoimmune encephalomyelitis in mice with a disrupted TCR delta chain gene
Spahn, T. W., Issazadeh-Navikas, Shohreh, Salvin, A. J. & Weiner, H. L., 1999, In: European Journal of Immunology. 29, 12, p. 4060-71 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Deficient Fas expression by CD4+ CCR5+ T cells in multiple sclerosis.
Julià, E., Montalban, X., Al-Zayat, H., Issazadeh-Navikas, Shohreh, Goertsches, R., Martin, R. & Comabella, M., 2006, In: Journal of Neuroimmunology. 180, 1-2, p. 147-58 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential Impact of Interferon Regulatory Factor 7 in Initiation of the Type I Interferon Response in the Lymphocytic Choriomeningitis Virus-Infected Central Nervous System versus the Periphery
Christensen, J. E., Fenger, C., Issazadeh-Navikas, Shohreh, Krug, A., Liljestrøm, P., Goriely, S., Paludan, S. R., Finsen, Bente, Christensen, Jan Pravsgaard & Thomsen, Allan Randrup, Jul 2012, In: Journal of Virology. 86, 13, p. 7384-7392 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential effects of B7-1 blockade in the rat experimental autoimmune encephalomyelitis model.
Gallon, L., Chandraker, A., Issazadeh-Navikas, Shohreh, Peach, R., Linsley, P. S., Turka, L. A., Sayegh, M. H. & Khoury, S. J., 1997, In: Journal of Immunology. 159, 9, p. 4212-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dual effects of vitamin D-induced alteration of TH1/TH2 cytokine expression: enhancing IgE production and decreasing airway eosinophilia in murine allergic airway disease.
Matheu, V., Bäck, O., Mondoc, E. & Issazadeh-Navikas, Shohreh, 2003, In: Journal of Allergy and Clinical Immunology. 112, 3, p. 585-92 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of a single dose of psilocybin on behaviour, brain 5-HT2A receptor occupancy and gene expression in the pig
Donovan, L. L., Johansen, Jens Vilstrup, Ros, N. F., Jaberi, E., Linnet, Kristian, Johansen, Sys Stybe, Ozenne, Brice Maxime Hugues, Issazadeh-Navikas, Shohreh, Hansen, H. D. & Knudsen, Gitte Moos, 2021, In: European Neuropsychopharmacology. 42, p. 1-11Research output: Contribution to journal › Journal article › Research › peer-review
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Elevated interleukin-12 in progressive multiple sclerosis correlates with disease activity and is normalized by pulse cyclophosphamide therapy.
Comabella, M., Balashov, K., Issazadeh-Navikas, Shohreh, Smith, D., Weiner, H. L. & Khoury, S. J., 1998, In: Journal of Clinical Investigation. 102, 4, p. 671-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Endogenous IFN-β signaling exerts anti-inflammatory actions in experimentally induced focal cerebral ischemia
Inácio, A. R., Liu, Yawei, Clausen, B. H., Svensson, M., Kucharz, Krzysztof, Yang, Y., Stankovich, T., Khorooshi, R., Lambertsen, K. L., Issazadeh-Navikas, Shohreh & Deierborg, T., 2015, In: Journal of Neuroinflammation. 12, p. 1-18 211.Research output: Contribution to journal › Journal article › Research › peer-review
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Endogenous collagen peptide activation of CD1d-restricted NKT cells ameliorates tissue-specific inflammation in mice
Liu, Yawei, Teige, A., Mondoc, E., Ibrahim, S., Holmdahl, R. & Issazadeh-Navikas, Shohreh, 4 Jan 2011, In: Journal of Clinical Investigation. 121, 1, p. 249-64 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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FoxA1 directs the lineage and immunosuppressive properties of a novel regulatory T cell population in EAE and MS
Liu, Yawei, Carlsson, R., Comabella, M., Wang, J., Kosicki, M. K., Carrion, B., Hasan, M., Wu, X., Montalban, X., Dziegiel, Morten Hanefeld, Sellebjerg, Finn Thorup, Sørensen, Per Soelberg, Helin, K. & Issazadeh-Navikas, Shohreh, 16 Feb 2014, In: Nature Medicine.Research output: Contribution to journal › Journal article › Research › peer-review
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FoxA1 in synergy with IFNβ controls PDL1 expression in anti-inflammatory T cells via binding to a 60-nucleotide region in the Pdl1 promoter
Hadi, M., Rasmussen, L. M., Kosicki, M., Carlsson, R. & Issazadeh-Navikas, Shohreh, Oct 2018, p. 596-597.Research output: Contribution to conference › Conference abstract for conference › Research
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FoxA1+ T regulatory cells as a predictive biomarker.
Issazadeh-Navikas, Shohreh, 2014, Patent No. PA 2015 70429Research output: Patent
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FoxA1+ T regulatory cells as biomarkers.
Issazadeh-Navikas, Shohreh, 2014, Patent No. PA 2015 70430Research output: Patent
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GABA, a natural immunomodulator of T lymphocytes
Bjurstöm, H., Wang, J., Ericsson, I., Bengtsson, M., Liu, Yawei, Kumar-Mendu, S., Issazadeh-Navikas, Shohreh & Birnir, B., 2008, In: Journal of Neuroimmunology. 205, 1-2, p. 44-50 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic analysis of inflammation, cytokine mRNA expression and disease course of relapsing experimental autoimmune encephalomyelitis in DA rats.
Lorentzen, J. C., Andersson, M., Issazadeh-Navikas, Shohreh, Dahlman, I., Luthman, H., Weissert, R. & Olsson, T., 1997, In: Journal of Neuroimmunology. 80, 1-2, p. 31-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic influence on disease course and cytokine response in relapsing experimental allergic encephalomyelitis.
Kjellén, P., Issazadeh-Navikas, Shohreh, Olsson, T. & Holmdahl, R., 1998, In: International Immunology. 10, 3, p. 333-40 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glycosylation of type II collagen is of major importance for T cell tolerance and pathology in collagen-induced arthritis.
Bäcklund, J., Treschow, A., Bockermann, R., Holm, B., Holm, L., Issazadeh-Navikas, Shohreh, Kihlberg, J. & Holmdahl, R., 2002, In: European Journal of Immunology. 32, 12, p. 3776-84 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Guidelines for the use and interpretation of assays for monitoring autophagy: 3rd edition
Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., Adhihetty, P. J., Adler, S. G., Agam, G., Agarwal, R., Aghi, M. K., Agnello, M., Agostinis, P., Aguilar, P. V., Aguirre-Ghiso, J., Airoldi, E. M. & 2,447 others, , 2016, In: Autophagy. 12, 1, p. 1-222 222 p.Research output: Contribution to journal › Review › Research › peer-review
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., Adamopoulos, I. E., Adeli, K., Adolph, T. E., Adornetto, A., Aflaki, E., Agam, G., Agarwal, A., Aggarwal, B. B., Agnello, M., Agostinis, P. & 2,908 others, , 2021, In: Autophagy. 17, p. 1-382 382 p.Research output: Contribution to journal › Review › Research › peer-review
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IFN-beta gene deletion leads to augmented and chronic demyelinating experimental autoimmune encephalomyelitis.
Teige, I., Treschow, A., Teige, A., Mattsson, R., Navikas, V., Leanderson, T., Holmdahl, R. & Issazadeh-Navikas, Shohreh, 2003, In: Journal of Immunology. 170, 9, p. 4776-84 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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IFN-beta inhibits T cell activation capacity of central nervous system APCs.
Teige, I., Liu, Yawei & Issazadeh-Navikas, Shohreh, 2006, In: Journal of Immunology. 177, 6, p. 3542-53 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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IFN-β rescues neurodegeneration by regulating mitochondrial fission via STAT5, PGAM5, and Drp1
Tresse-Gommeaux, Emilie, Riera Ponsati, Lluis, Jaberi, E., Sew, W. Q. G., Ruscher, K. & Issazadeh-Navikas, Shohreh, 2021, In: E M B O Journal. 40, 11, e106868.Research output: Contribution to journal › Journal article › Research › peer-review
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IFNB1/interferon-ß-induced autophagy in MCF-7 breast cancer cells counteracts its proapoptotic function
Ambjørn, M., Ejlerskov, P., Liu, Yawei, Lees, M., Jäättelä, M. & Issazadeh-Navikas, Shohreh, Mar 2013, In: Autophagy. 9 , 3, p. 287-302Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of unique and shared mitochondrial DNA mutations in neurodegeneration and cancer by single-cell mitochondrial DNA structural variation sequencing (MitoSV-seq)
Jaberi, E., Tresse-Gommeaux, Emilie, Grønbæk, Kirsten, Weischenfeldt, Joachim Lütken & Issazadeh-Navikas, Shohreh, 2020, In: EBioMedicine. 57, p. 1-17 102868.Research output: Contribution to journal › Journal article › Research › peer-review
Immunoregulation and immunogenetics of monophasic and relapsing EAE with emphasis on cytokines: (KI, ISBN 91-628-2002-8)
Issazadeh-Navikas, Shohreh, May 1996Research output: Book/Report › Book › Research › peer-review
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Impact on allergic immune response after treatment with vitamin A
Matheu, V., Berggård, K., Barrios, Y., Barrios, Y., Arnau, M., Zubeldia, J. M., Baeza, M. L., Back, O. & Issazadeh-Navikas, Shohreh, 2009, In: Nutrition & Metabolism. 6, p. 44Research output: Contribution to journal › Journal article › Research › peer-review
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In vivo mechanisms of acquired thymic tolerance.
Chen, W., Issazadeh-Navikas, Shohreh, Sayegh, M. H. & Khoury, S. J., 1997, In: Cellular Immunology. 179, 2, p. 165-73 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Induction of endogenous Type I interferon within the central nervous system plays a protective role in experimental autoimmune encephalomyelitis
Khorooshi, R., Mørch, M. T., Holm, T. H., Berg, C. T., Dieu, R. T., Dræby, D., Issazadeh-Navikas, Shohreh, Weiss, S., Lienenklaus, S. & Owens, T., 14 Apr 2015, In: Acta Neuropathologica.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of dietary components on regulatory T cells
Issazadeh-Navikas, Shohreh, Teimer, R. & Bockermann, R., 2011, In: Molecular medicine (Cambridge, Mass.).Research output: Contribution to journal › Review › Research › peer-review
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Inhibition of CXCL12 signaling attenuates the postischemic immune response and improves functional recovery after stroke
Ruscher, K., Kuric, E., Liu, Yawei, Walter, H. L., Issazadeh-Navikas, Shohreh, Englund, E. & Wieloch, T., 1 May 2013, In: Journal of Cerebral Blood Flow and Metabolism.Research output: Contribution to journal › Journal article › Research › peer-review
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Innate and adaptive stimulation of murine diverse NKT cells result in distinct cellular responses
Tripathi, P., Sedimbi, S. K., Singh, A. K., Löfbom, L., Issazadeh-Navikas, Shohreh, Weiss, S., Förster, I., Karlsson, M. C. I., Yrlid, U., Kadri, N. & Cardell, S. L., 2019, In: European Journal of Immunology. 49, 3, p. 443-453 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 3998988
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Neuronal IFN-beta-induced PI3K/Akt-FoxA1 signalling is essential for generation of FoxA1(+)Treg cells
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Angiotensinogen and HLA class II predict bevacizumab response in recurrent glioblastoma patients
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RhoA Drives T-Cell Activation and Encephalitogenic Potential in an Animal Model of Multiple Sclerosis
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