Katrine Ter-Borch Gram Schjoldager
Associate Professor - Promotion Programme
Glycomics Program
Blegdamsvej 3, 2200 København N.
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A Bump-and-Hole Approach to Dissect Regulation of Protein O-Glycosylation
Schjoldager, Katrine Ter-Borch Gram, Clausen, Henrik & Hurtado-Guerrero, R., 2020, In: Molecular Cell. 78, 5, p. 803-805 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A glycogene mutation map for discovery of diseases of glycosylation
Hansen, Lars, Lind-Thomsen, A., Joshi, Hiren Jitendra, Pedersen, N. B., Have, C. T., Kong, Y., Wang, S., Sparso, T., Grarup, Niels, Vester-Christensen, M. B., Schjoldager, Katrine Ter-Borch Gram, Freeze, H. H., Hansen, Torben, Pedersen, Oluf Borbye, Henrissat, B., Mandel, Ulla, Clausen, Henrik, Wandall, Hans H. & Bennett, Eric Paul, 2015, In: Glycobiology. 25, 2, p. 211-224 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A systematic study of modulation of ADAM-mediated ectodomain shedding by site-specific O-glycosylation
Goth, C. K., Halim, Adnan, Khetarpal, S. A., Rader, D. J., Clausen, Henrik & Schjoldager, Katrine Ter-Borch Gram, 24 Nov 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 47, p. 14623-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A systematic study of site-specific GalNAc-type O-glycosylation modulating proprotein convertase processing
Schjoldager, Katrine Ter-Borch Gram, Vester-Christensen, M. B., Goth, C. K., Petersen, T. N., Brunak, Søren, Bennett, Eric Paul, Levery, S. B. & Clausen, Henrik, 18 Nov 2011, In: Journal of Biological Chemistry. 286, 46, p. 40122-32 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A validated collection of mouse monoclonal antibodies to human glycosyltransferases functioning in mucin-type O-glycosylation.
Steentoft, C., Yang, Zhang, Wang, S., Ju, T., Vester-Christensen, M. B., Festari, M. F., King-Smith, S. L., Moremen, K., Larsen, I. S. B., Goth, C. K., Schjoldager, Katrine Ter-Borch Gram, Hansen, Lars, Bennett, Eric Paul, Mandel, Ulla & Narimatsu, Yoshiki, 2019, In: Glycobiology. 29, 9, p. 645–656 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A validated gRNA library for CRISPR/Cas9 targeting of the human glycosyltransferase genome
Narimatsu, Yoshiki, Joshi, Hiren Jitendra, Zhang, Y., Gomes, C., Chen, Yen-Hsi, Lorenzetti, F., Furukawa, S., Schjoldager, Katrine Ter-Borch Gram, Hansen, Lars, Clausen, Henrik, Bennett, Eric Paul & Wandall, Hans H., 2018, In: Glycobiology. 28, 5, p. 295–305Research output: Contribution to journal › Journal article › Research › peer-review
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An Atlas of Human Glycosylation Pathways Enables Display of the Human Glycome by Gene Engineered Cells
Narimatsu, Y., Joshi, H. J., Nason, R., Van Coillie, J., Karlsson, R., Sun, L., Ye, Z., Chen, Y-H., Schjoldager, K. T., Steentoft, C., Furukawa, S., Bensing, B. A., Sullam, P. M., Thompson, A. J., Paulson, J. C., Büll, C., Adema, G. J., Mandel, U., Hansen, L., Bennett, E. P. & 4 others, , 2019, In: Molecular Cell. 75, 2, p. 394-407, e1-e5Research output: Contribution to journal › Journal article › Research › peer-review
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An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles
Madsen, Thomas Daugbjerg, Hansen, L. H., Hintze, John, Ye, Z., Jebari, S., Andersen, Daniel Bjørklund, Joshi, Hiren Jitendra, Ju, T., Goetze, Jens P. , Martin, C., Rosenkilde, Mette, Holst, Jens Juul, Kuhre, Rune Ehrenreich, Goth, C. K., Vakhrushev, Sergey & Schjoldager, Katrine Ter-Borch Gram, 2020, In: Nature Communications. 11, 1, 13 p., 4033.Research output: Contribution to journal › Journal article › Research › peer-review
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Cellular cross talk in the small intestinal mucosa: postnatal lymphocytic immigration elicits a specific epithelial transcriptional response
Schjoldager, Katrine Ter-Borch Gram, Maltesen, H. R., Balmer, S., Lund, L. R., Claesson, Mogens Helweg, Sjöström, H., Troelsen, J. T. & Olsen, Jørgen, 2008, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 294, 6, p. G1335-43Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of an immunodominant cancer-specific O-glycopeptide epitope in murine podoplanin (OTS8)
Steentoft, C., Schjoldager, Katrine Ter-Borch Gram, Cló, E., Mandel, Ulla, Levery, S. B., Pedersen, J. W., Jensen, Knud Jørgen, Blixt, O. & Clausen, Henrik, 2010, In: Glycoconjugate Journal. 27, 6, p. 571-82 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterizing the O-glycosylation landscape of human plasma, platelets, and endothelial cells
King-Smith, S. L., Joshi, Hiren Jitendra, Schjoldager, Katrine Ter-Borch Gram, Halim, Adnan, Madsen, Thomas Daugbjerg, Dziegiel, Morten Hanefeld, Woetmann, Anders , Vakhrushev, Sergey & Wandall, Hans H., 2017, In: Blood advances. 1, 7, p. 429-442 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Chromogranin A in the mammalian heart: Expression without secretion
Hansen, L. H., Darkner, S., Svendsen, Jesper Hastrup, Henningsen, K., Pehrson, S., Chen, X., Vakhrushev, Sergey, Schjoldager, Katrine Ter-Borch Gram & Goetze, Jens P. , Jul 2017, In: Biomarkers in Medicine. 11, 7, p. 541-545 5 p.Research output: Contribution to journal › Letter › Research › peer-review
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Deconstruction of O-glycosylation-GalNAc-T isoforms direct distinct subsets of the O-glycoproteome
Schjoldager, Katrine Ter-Borch Gram, Joshi, Hiren Jitendra, Kong, Y., Goth, C. K., King-Smith, S. L., Wandall, Hans H., Bennett, Eric Paul, Vakhrushev, Sergey & Clausen, Henrik, Dec 2015, In: E M B O Reports. 16, 12, p. 1713-22 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Development of isoform-specific sensors of polypeptide GalNAc-transferase activity
Song, L., Bachert, C., Schjoldager, Katrine Ter-Borch Gram, Clausen, Henrik & Linstedt, A. D., 31 Oct 2014, In: The Journal of Biological Chemistry. 289, 44, p. 30556-66 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Discovery of O-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor
Hansen, L. H., Madsen, Thomas Daugbjerg, Goth, C. K., Clausen, Henrik, Chen, Y., Dzhoyashvili, N., Iyer, S. R., Sangaralingham, S. J., Burnett, J. C., Rehfeld, Jens Frederik, Vakhrushev, Sergey, Schjoldager, Katrine Ter-Borch Gram & Goetze, Jens P. , 2019, In: Journal of Biological Chemistry. 294, 34, p. 12567-12578 12 p.Research output: Contribution to journal › Review › Research › peer-review
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Exploring Regulation of Protein O-Glycosylation in Isogenic Human HEK293 Cells by Differential O-Glycoproteomics
Narimatsu, Yoshiki, Joshi, Hiren Jitendra, Schjoldager, Katrine Ter-Borch Gram, Hintze, John, Halim, Adnan, Steentoft, C., Nason, R., Mandel, Ulla, Bennett, Eric Paul, Clausen, Henrik & Vakhrushev, Sergey, 2019, In: Molecular and Cellular Proteomics. 18, 7, p. 1396-1409Research output: Contribution to journal › Journal article › Research › peer-review
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Fine-Tuning Limited Proteolysis: A Major Role for Regulated Site-Specific O-Glycosylation
Goth, C. K., Vakhrushev, Sergey, Joshi, Hiren Jitendra, Clausen, Henrik & Schjoldager, Katrine Ter-Borch Gram, 2018, In: Trends in Biochemical Sciences. 43, 4, p. 269-284 16 p.Research output: Contribution to journal › Review › Research › peer-review
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Fine-tuning limited proteolysis - A novel role for regulated site-specific O-glycosylation in beta 1-Adrenergic Receptor cleavage and function
Goth, C. K., Tuhkanen, H. E., Khan, H., Wang, S., Narimatsu, Yoshiki, Hansen, L. H., Overall, C., Clausen, Henrik, Schjoldager, Katrine Ter-Borch Gram & Petaja-Repo, U., Dec 2017, In: Glycobiology. 27, 12, p. 1204-1204 84.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Galnt11 regulates kidney function by glycosylating the endocytosis receptor megalin to modulate ligand binding
Tian, E., Wang, S., Zhang, L., Zhang, Y., Malicdan, M. C., Mao, Y., Christoffersen, Christina, Tabak, L. A., Schjoldager, Katrine Ter-Borch Gram & Ten Hagen, K. G., 10 Dec 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 50, p. 25196-25202Research output: Contribution to journal › Journal article › Research › peer-review
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Global view of human protein glycosylation pathways and functions
Schjoldager, Katrine Ter-Borch Gram, Narimatsu, Yoshiki, Joshi, Hiren Jitendra & Clausen, Henrik, 2020, In: Nature Reviews Molecular Cell Biology. 21, p. 729–749Research output: Contribution to journal › Review › Research › peer-review
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GlycoDomainViewer: A bioinformatics tool for contextual exploration of glycoproteomes
Joshi, Hiren Jitendra, Jørgensen, A., Schjoldager, Katrine Ter-Borch Gram, Halim, Adnan, Dworkin, L. A., Steentoft, C., Wandall, Hans H., Clausen, Henrik & Vakhrushev, Sergey, 1 Mar 2018, In: Glycobiology. 28, 3, p. 131-136 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glycoproteomics
Bagdonaite, Ieva , Malaker, S. A., Polasky, D. A., Riley, N. M., Schjoldager, Katrine Ter-Borch Gram, Vakhrushev, Sergey, Halim, Adnan, Aoki-Kinoshita, K. F., Nesvizhskii, A. I., Bertozzi, C. R., Wandall, Hans H., Parker, B. L., Thaysen-Andersen, M. & Scott, N. E., 2022, In: Nature Reviews Methods Primers. 2, 1, 29 p., 48.Research output: Contribution to journal › Review › Research › peer-review
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Glycosyltransferase genes that cause monogenic congenital disorders of glycosylation are distinct from glycosyltransferase genes associated with complex diseases
Joshi, Hiren Jitendra, Hansen, Lars, Narimatsu, Yoshiki, Freeze, H. H., Henrissat, B., Bennett, Eric Paul, Wandall, Hans H., Clausen, Henrik & Schjoldager, Katrine Ter-Borch Gram, 2018, In: Glycobiology. 28, 5, p. 284-294Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of distinct glycoforms of IgA1 in plasma from patients with IgA nephropathy and healthy individuals
Lehoux, S., Mi, R., Aryal, R. P., Wang, Y., Schjoldager, Katrine Ter-Borch Gram, Clausen, Henrik, Van Die, I., Han, Y., Chapman, A. B., Cummings, R. D. & Ju, T., Nov 2014, In: Molecular & Cellular Proteomics. 13, 11, p. 3097-113 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of global inhibitors of cellular glycosylation
Sørensen, D. M., Büll, C., Madsen, T. D., Lira-Navarrete, E., Clausen, T. M., Clark, A. E., Garretson, A. F., Karlsson, R., Pijnenborg, J. F. A., Yin, X., Miller, R. L., Chanda, S. K., Boltje, T. J., Schjoldager, K. T., Vakhrushev, S. Y., Halim, A., Esko, J. D., Carlin, A. F., Hurtado-Guerrero, R., Weigert, R. & 2 others, , 2023, In: Nature Communications. 14, 1, 19 p., 948.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 920646
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Discovery of O-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor
Research output: Contribution to journal › Review › Research › peer-review
Published -
102
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An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
34
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The SHDRA syndrome-associated gene TMEM260 encodes a protein-specific O-mannosyltransferase
Research output: Contribution to journal › Journal article › Research › peer-review
Published